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Identification

Personal identification

Full name
Maria Leonor Matos Resina

Citation names

  • Resina, Leonor

Author identifiers

Ciência ID
EB15-D477-6CDC
ORCID iD
0000-0003-4216-8349

Email addresses

  • maria.leonor.matos@upc.edu (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Medical Engineering
  • Engineering and Technology - Materials Engineering
  • Engineering and Technology - Nano-technology - Nano-materials
  • Engineering and Technology - Chemical Engineering
  • Engineering and Technology - Industrial Biotechnology
  • Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2020/01/31 - 2024/01
Ongoing
Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universitat Politècnica de Catalunya Department d´Enginyeria Química, Spain
2014/09/15 - 2017/06/23
Concluded
Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"The Role of Tauroursodeoxycholic Acid for the Expansion and Neural Differentiation of Human Induced Pluripotent Stem Cells under Chemically-defined Conditions" (THESIS/DISSERTATION)
17
2010/09/13 - 2015/07/01
Concluded
Engenharia Biológica (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
15
Affiliation

Science

Category
Host institution
Employer
2024/03/01 - Current Research Assistant (Research) Universitat Politècnica de Catalunya, Spain
Universitat Politècnica de Catalunya, Spain

Others

Category
Host institution
Employer
2018/11/26 - 2019/10/31 Bolseiro de Investigação Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2016/09/19 - 2017/06/23 Estagiário de Investigação Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2011/07/01 - 2011/07/31 Estagiário de Investigação Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Centro de Química Estrutural, Portugal
Projects

Grant

Designation Funders
2018/11/26 - 2019/10/31 Bioorganic novel approaches for food processing waste water treatment and valorisation: Lupanine case study
WaterWorks2014, ID 278
WaterJPI/0002/2014
Research Fellow
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2022/01/17 - 2025/01/16 Modelos in silico que orientam a estimulação biofísica in vitro de scaffolds hierárquicos biomiméticos: uma abordagem de modelação computacional visando a regeneração osteocondral funcional
PTDC/EME-SIS/0838/2021
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Instituto Politécnico de Leiria, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2025 Hydrogel-based multifunctional conductive and interactive platforms for biomedical applications: cardiac, skin and nervous tissue restoration
PID2021-125767OB-I00
PhD Student Fellow
Universitat Politècnica de Catalunya, Spain
Agencia Estatal de Investigación
Ongoing
2023/03/01 - 2024/08/31 Nanobioeletrónica multifuncional ativada sem fios para novas terapias oncológicas
2022.07252.PTDC
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/03/29 - 2024/03/28 OptiBioScaffold: Optimização de estímulos em scaffolds bi-tecido: da modelação matemática e computacional à validação experimental
PTDC/EME-SIS/4446/2020
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal

Instituto Politécnico de Leiria, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 New electro-responsive materials platforms for cancer treatment: Smart self-growing nanoparticles and transdermal devices
SFRH/BD/145057/2019
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2022/09/30 Suportes celulares magneto-sensíveis 3D para estudos de vascularização
PTDC/EMD-EMD/30828/2017
Associação para a Inovação e Desenvolvimento da FCT, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/10/01 - 2022/06/30 Plataformas condutoras elétricas para cultura e diferenciação de células estaminais neurais
PTDC/CTM-CTM/30237/2017
Instituto de Telecomunicações Lisboa, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Resina, Leonor. "Dendritic self-assembled structures from anticancer pentapeptides". Paper presented in ACS Fall 2023, 2023.
  2. Resina, Leonor. "Electro-Responsive and pH-Sensitive Hydrogel as Carrier for Controlled Drug Release". Paper presented in 3rd iBB Workshop, 2023.
  3. Miguel, Filipe. "Biomimetic conductive hydrogel loaded with Kartogenin-PEDOT nanoparticles for cartilage tissue engineering". Paper presented in European Orthopaedic Research Society EORS 2023, 2023.
  4. Resina, Leonor. "Multiresponsive hydrogel as carrier for controlled chloramphenicol release". Paper presented in ACS Fall 2023, 2023.
  5. Resina, Leonor. "Wireless electrostimulation for cancer treatment: an integrated nanoparticle/coaxial fiber mesh platform". Paper presented in Ciência 2023, 2023.
  6. Resina, Leonor. "Nanomaterial-based wireless electrostimulation platform for cancer treatment". Paper presented in Advanced Functional Polymers for Medicine 2023, 2023.
  7. Resina, Leonor. "Electro-Responsive and pH-Sensitive Hydrogel as Carrier for Controlled Drug Release". Paper presented in Advanced Functional Polymers for Medicine 2023, 2023.
  8. Ramirez, Maria Dolores. "Multifunctional hydrogels and biopolymer blend scaffolds for skin tissue regeneration". Paper presented in Advanced Functional Polymers for Medicine 2023, 2023.
  9. Miguel, Filipe. "Electrically conductive hydrogel loaded with PEDOT-Kartogenin nanoparticles for articular cartilage regeneration". Paper presented in TERMIS-EU Chapter Meeting 2023, 2023.
  10. Fábio F. F. Garrudo. "Development of electroactive composites for the electrical stimulation of stem cells". Paper presented in TERMIS-EU Chapter Meeting 2023, 2023.
  11. Barbosa, Frederico. "Novel piezoelectric and osteoinductive electrospun nanofibers for bone tissue engineering". Paper presented in TERMIS-EU Chapter Meeting 2023, 2023.
  12. Resina, Leonor. "Wireless electrostimulation for cancer treatment using an integrated nanoparticle/coaxial fiber mesh platform". Paper presented in 2nd iBB Workshop, 2022.
  13. Gomes, AR; Fernandes, TG; Resina, L; Pinho, J; Ribeiro, MF; Rodrigues, CMP; Cabral, JMS; Solá, S; Diogo, MM. "Tauroursodeoxycholic Acid Increases Neural Rosette Number upon Neural Induction of Human Induced Pluripotent Stem Cells". Paper presented in 10th International Meeting of The Portuguese Society for Stem Cells and Cell Therapies, 2017.
Journal article
  1. Resina, Leonor; Alemán, Carlos; Ferreira, Frederico Castelo; Esteves, Teresa. Corresponding author: Esteves, Teresa. "Protein-imprinted polymers: How far have “plastic antibodies” come?". Biotechnology Advances 68 (2023): 108220. http://dx.doi.org/10.1016/j.biotechadv.2023.108220.
    Open access • Published • 10.1016/j.biotechadv.2023.108220
  2. Barbosa, Frederico; Garrudo, Fábio F. F.; Alberte, Paola S.; Resina, Leonor; Carvalho, Marta S.; Jain, Akhil; Marques, Ana C.; et al. "Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering". Science and Technology of Advanced Materials 24 1 (2023): http://dx.doi.org/10.1080/14686996.2023.2242242.
    Published • 10.1080/14686996.2023.2242242
  3. Garrudo, Fábio F. F.; Filippone, Giulia; Resina, Leonor; Silva, João C.; Barbosa, Frederico; Ferreira, Luís F. V.; Esteves, Teresa; et al. "Production of Blended Poly(acrylonitrile): Poly(ethylenedioxythiophene):Poly(styrene sulfonate) Electrospun Fibers for Neural Applications". Polymers 15 13 (2023): 2760. http://dx.doi.org/10.3390/polym15132760.
    Open access • Published • 10.3390/polym15132760
  4. Resina, Leonor; El Hauadi, Karima; Sans, Jordi; Esteves, Teresa; Ferreira, Frederico Castelo; Pérez-Madrigal, Maria M.; Alemán, Carlos. Corresponding author: Pérez-Madrigal, Maria M.. "Electroresponsive and pH-Sensitive Hydrogel as Carrier for Controlled Chloramphenicol Release". Biomacromolecules 24 3 (2023): 1432-1444. http://dx.doi.org/10.1021/acs.biomac.2c01442.
    Published • 10.1021/acs.biomac.2c01442
  5. El Hauadi, Karima; Resina, Leonor; Zanuy, David; Esteves, Teresa; Ferreira, Frederico Castelo; Pérez-Madrigal, Maria M.; Alemán, Carlos. Corresponding author: Alemán, Carlos. "Dendritic Self-assembled Structures from Therapeutic Charged Pentapeptides". Langmuir 38 42 (2022): 12905-12914. http://dx.doi.org/10.1021/acs.langmuir.2c02010.
    Published • 10.1021/acs.langmuir.2c02010
  6. Ferreira, Flávio; Resina, Leonor; Esteves, Teresa; Ferreira, Frederico Castelo. "Comparison and Combination of Organic Solvent Nanofiltration and Adsorption Processes: A Mathematical Approach for Mitigation of Active Pharmaceutical Ingredient Losses during Genotoxin Removal". Membranes 10 4 (2020): 73. http://dx.doi.org/10.3390/membranes10040073.
    Open access • 10.3390/membranes10040073
Thesis / Dissertation
  1. Resina, Leonor. "The Role of Tauroursodeoxycholic Acid for the Expansion and Neural Differentiation of Human Induced Pluripotent Stem Cells under Chemically-defined Conditions". Master, Universidade de Lisboa Instituto Superior Técnico, 2017. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=2ahUKEwir_6W88PrgAhUPyYUKHaimDXMQFjAAegQIABAC&url=https%3A%2F%2Ffenix.tecnico.ulisboa.pt%2FdownloadFile%2F1126295043835181%2FMScThesis%2520M%2520Leonor%2520Resina%252070161.pdf&usg=AOvVaw.

Intellectual property

Provisional application for patent
  1. 2023. "Hidrogel Eletrocondutor Autoregenerável, Suas Composições, Usos E Métodos De Obtenção".
    Protected
  2. 2023. "SELF-HEALING ELECTROCONDUCTIVE HYDROGELS, THEIR COMPOSITION, USES, AND METHODS OF PRODUCTION".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/08 Using nanomaterials for cancer treatment: a wireless electrostimulation platform ACS Fall 2023
American Chemical Society (San Francisco, United States)
2023/08 Highly electroconductive PEDOT:PSS platforms for electrical stimulation studies of neural-differentiating iPSCs ACS Fall 2023
American Chemical Society (United States)
2023/08 Development of electroconductive PAN/PEDOT electrospun fibers for tissue engineering applications ACS Fall 2023
American Chemical Society (United States)
2023/04 Wireless electrostimulation for cancer treatment: an integrated nanoparticle/coaxial fiber mesh platform TERMIS-EU Chapter Meeting 2023
Tissue Engineering and Regenerative Medicine International Society (TERMIS) (Manchester, United Kingdom)
2023/04 Electrical stimulation positively interferes on induced pluripotent stem cell neural differentiation at different stages TERMIS-EU Chapter Meeting 2023
Tissue Engineering and Regenerative Medicine International Society (TERMIS) (Manchester, United Kingdom)
2023 Controlled therapeutic peptide release using nanoparticles and hydrogels Peptide Materials 2023
(Sorrento, Italy)
2023 Wireless electrostimulation nanomaterials platform for cancer treatment NanoSpain 2023
(Tarragona, Spain)
2019/04/08 Membrane process for water recycle and lupanine recovery on lupin bean processing Engineering with Membranes Conference 2019
(Bastad, Sweden)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/03/01 - 2024/06 Conductive systems based on limonene membranes for skin regeneration / Sistemas conductores basados en membranas de limoneno para regeneración de la piel
Co-supervisor of Pau Caballero
Chemical Engineering (Degree)
Universitat Politècnica de Catalunya, Spain

Event participation

Activity description
Type of event
Event name
Institution / Organization
2018/09/01 - 2018/09/10 Massive Open Online Course on Markov Matrices lectured by Prof. Ana Moura Santos. The concepts that were addressed were Markov chains, transition matrices, (i.e. Markov matrices), stationary vectors integrated in linear models, which allow predicting future states (or times of average occupation) of the chain, that is, to predict the long-term statistical behaviour of the chain. Final grade: 90%.
Other
MOOC Técnico - Matrizes de Markov
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/02/02 - 2015/02/06 Monitora nos Laboratórios Abertos 2015 do Departamento de Engenharia Química do IST. Responsável por apresentar experiências de laboratório na temática da química a estudantes do ensino básico e secundário. Responsável por supervisionar outros monitores menos experientes.
Other
Laboratórios Abertos 2015
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/02/03 - 2014/02/07 Monitora nos Laboratórios Abertos 2014 do Departamento de Engenharia Química do IST. Responsável por apresentar experiências de laboratório na temática da química a estudantes do ensino básico e secundário. Responsável por supervisionar outros monitores menos experientes.
Other
Laboratórios Abertos 2014
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011/02/07 - 2011/02/11 Monitora nos Laboratórios Abertos 2011 do Departamento de Engenharia Química do IST. Responsável por apresentar experiências de laboratório na temática da química a estudantes do ensino básico e secundário.
Other
Laboratórios Abertos 2011
Universidade de Lisboa Instituto Superior Técnico, Portugal

Mentoring / Tutoring

Topic Student name
2023/10/01 - 2024/01 LIMONENE-BASED 3D CONDUCTIVE PLATFORMS FOR SKIN CARE APPLICATIONS / PLATAFORMAS CONDUCTORAS 3D BASADAS EN LIMONENO PARA APLICACIONES DE CUIDADO DE LA PIEL Pilar Casale