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Maria Teresa Tenório Figueiredo Carvalho Gonçalves. Concluiu o(a) Doutoramento em Licenciatura em Medicina em 2001 pelo(a) Universidade de Lisboa Faculdade de Medicina. É Professor Auxiliar no(a) Universidade de Lisboa Faculdade de Medicina e Investigador no(a) Instituto de Medicina Molecular. Participa e/ou participou como Investigador em 22 projeto(s). No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Biological Sciences - Molecular and Structural Biology; Health Sciences - Molecular Medicine; Biology and Medicine; Basic Biological Research; .
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Identification

Personal identification

Full name
Maria Teresa Tenório Figueiredo Carvalho Gonçalves

Citation names

  • Carvalho, Teresa

Author identifiers

Ciência ID
EC1A-86D9-0436
ORCID iD
0000-0001-7061-8904

Languages

Language Speaking Reading Writing Listening Peer-review
French Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2001
Concluded
 Licenciatura em Medicina (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
 Distinçao e Louvor com 19 valores
1995
Concluded
 Provas de Aptidão Pedagógica e Capacidade Científica (Mestrado)
Major in Biologia Celular e Molecular
Universidade de Lisboa Faculdade de Medicina, Portugal
 Muito Bom
1988
Concluded
 Medicina (Licenciatura)
Universidade de Lisboa Faculdade de Medicina, Portugal
 16,2
Affiliation

Science

Category
Host institution 		Employer
1989 - Current Researcher (Research) Instituto de Medicina Molecular, Portugal
2017 - 2018 Researcher (Research) Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2001/07/07 - Current Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Medicina, Portugal

Others

Category
Host institution 		Employer
1996/01/01 - 2001/06/06 Assistente de Biologia Molecular da Célula Universidade de Lisboa Faculdade de Medicina, Portugal
Projects

Contract

Designation Funders
2024 - 2029 Optimized Oligo Escape and Control of Disease
#0081287
Researcher
Instituto de Medicina Molecular, Portugal
Ongoing
2022 - 2026 Cardiac Splicing as a Therapeutic Target.
21CVD02 – (CASTT)
Researcher
Instituto de Medicina Molecular, Portugal
Ongoing
2022 - 2024 Mutação BRCA2 fundadora Portuguesa: impacto na transcrição e identidade de células estaminais.
PTDC/MED-ONC/3921/2021
Researcher
Instituto de Medicina Molecular, Portugal
Ongoing
2017 - 2024 The Discoveries Centre for Regenerative and Precision Medicine
(H2020-WIDESPREAD-01-2016-2017-TeamingPhase2
Researcher
Instituto de Medicina Molecular, Portugal
2020 - 2023 Investigating the causes of mutation-negative hypertrophic cardiomyopathy: Role of Cryptic RNA mis-splicing in myosin binding protein C (MYBPC3)
BHF PG/20/10170
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2020 - 2023 RNA mis-splicing in hypertrophic cardiomyopathy: opportunities for diagnosis and therapy
HR20-00322
Researcher
Ongoing
2018 - 2022 CardioRNA COST Action.
CA17129
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2018 - 2021 Gene-edited organoids to study the functional impact of BRCA1 and BRCA2 mutations
PTDC/MED-ONC/29469/2017
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2016 - 2019 Making sense of antisense transcription
FCT-PTDC/BEX-BCM/5899/2014
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2016 - 2019 Accelerating progress toward the new area of Precision medicine
Precise
Researcher
Ongoing
2013 - 2016 Determining the effect of CLK inhibitors on cancer associated alternative splicing
Servier
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2014 - 2015 Exploring new therapeutic approaches for Hypertrophic Cardiomyopathy
EXPL/BIM-MEC/0201/2013
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2011 - 2015 RNPnet: RNP structure, function and mechanism of action (Marie Curie Initial Training Network)
RNPnet
Researcher
Instituto de Medicina Molecular, Portugal
2012 - 2014 Identification and manipulation of molecular pathways relevant for age-dependent tissue regeneration
AXA Research Fund
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2012 - 2014 Splicing and stochasticity in programmed cell death decisions
FCT-PTDC/SAU-GMG/ 118180/2010
Researcher
Instituto de Medicina Molecular, Portugal
2010 - 2013 The role of RNA polymerase II in splicing regulation
FCT-PTDC/SAU-GMG/ 113440/2009
Researcher
2011 - 2012 EXPLORING RNA-TARGETED GENE THERAPY APPROACHES FOR HYPERTROPHIC CARDIOMYOPATHY
Fundação Amadeu Dias
Co-Principal Investigator (Co-PI)
Concluded
2009 - 2012 Transcription-coupled mechanisms of gene regulation.
FCT-PTDC/ BIABCM/ 101575/ 2008
Instituto de Medicina Molecular, Portugal
Concluded
2006 - 2010 EURASNET: European Alternative Splicing Network
FP6-LSHG-CT-2005-518238
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2007 - 2009 Mechanisms of splicing regulation by U2AF proteins
FCT-PTDC/SAU-GMG/69739/2006
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2006 - 2009 Chromatin Plasticity
FP6- Marie Curie Training Network
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2004 - 2009 MOLECULAR IMAGING-Integrated technologies for in vivo molecular imaging
FP6-2002-CT-503259
Researcher
Concluded
2004/01/01 - 2008 Regulation of mRNA processing and transport within the nucleus
info:eu-repo/grantAgreement/FCT/3599-PPCDT/82325/PT
 Fundação para a Ciência e a Tecnologia
Concluded
2005/02/01 - 2007 EURODYNA 2007-05: Cell biology of messenger RNA biogenesis
info:eu-repo/grantAgreement/SNSF/Project funding/31DY30-108704/CH
 Fundação para a Ciência e a Tecnologia
2001/01/31 - 2004 Macromolecules in Motion Inside the Living Cell
info:eu-repo/grantAgreement/FCT/POCI/36511/PT
Universidade de Lisboa Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001 - 2004 Genetic Dieseases and RNA Processing. Projecto financiado pela Ciência e Tecnologia.
SAPIENS 36547/99
Researcher
Instituto de Medicina Molecular, Portugal
Concluded
2001 - 2004 RNOMICS-An integrated analysis of links between pathways of RNA metabolism in post genomic era.
QLRT-2000-01554
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
2000 - 2002 Gene expression in 4 dimensions
PRAXIS BIO/12085/98
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
1995 - 1998 Cellular and animal models for the investigation of gene regulation in the native environment of the living cell nucleus.
BMH4-98-3147
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
1995 - 1998 Functional organization of the cell nucleus:implications for viral pathogenesis and oncogenesis.
PRAXIS SAU/1310/95
Researcher
1994 - 1996 Nuclear Organization during interphase and mitosis.
PRAXIS SAU/06/94
Researcher
1990 - 1994 Molecular and Cell Biology of RNA processing. European Union, Human Capital and Mobility Program.
Angus Lamond -CT930251
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
1990 - 1992 Characterization of a novel calcium binding protein localized in the nucleus.
STRADA/SAU/256/92
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Carmo-Fonseca, Maria; Bohmann, Kerstin; Carvalho, Teresa; Lamond, Angus I.. "P80 coilin". In Manual of Biological Markers of Disease, 1-11. Springer Netherlands, 1994.
    10.1007/978-94-011-1670-1_36
Conference poster
  1. Carvalho, Teresa; Martins, Sandra; Ribeiro Marta; Furtado Marta; Carmo-Fonseca, M; Lopes Luís; Tavares, Joana; Petros Syrris P; Mohammed Akhtar. "Ribeiro M., Furtado M., Carvalho T., Martins S., Tavares J., Lopes L., Syrris P P., Akhtar M., Elliot P., Carmo-Fonseca M. (2019) An improved tissue engineering protocol to generate cardiomyocytes from patient iPSCs. Annual Meeting of the ESC Working Group on Myocardial & Pericardial Diseases. Coruña, Spain, 4-5 October 2019.". Paper presented in Annual Meeting of the ESC Working Group on Myocardial & Pericardial Diseases, 2019.
  2. Carvalho, Teresa; Gonçalves Rodrigo; Ribeiro Marta; Martins, Sandra; Carmo-Fonseca, M. "Gonçalves Rodrigo, Ribeiro M., Martins S., Carvalho T., Carmo-Fonseca (2017). Analysis of alternative splicing in hiPSC derived cardiomyocytes. 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Covilhã, Portugal, 12-14 Oct, 2017". Paper presented in 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2017.
  3. Carvalho, Teresa; Martins, Sandra Bento; Mendes de Almeida, Rita; Carmo-Fonseca, M; Santos, C.. ".Martins S., Carvalho, T., Mendes de Almeida, R., Santos, C. and Carmo-Fonseca M. (2015). Using the CRISPR technology to develop cellular models of Hypertrophic Cardiomyopathy. CRISPR 2015 Oxford Symposia, St Hilda´s College, Oxford, U . 23th March 2015.". Paper presented in Oxford Symposia, St Hilda´s College, 2015.
  4. Carvalho, Teresa; Mendes de Almeida, Rita; Martins, Sandra Bento; Carmo-Fonseca, M. "Mendes de Almeida R., Carvalho T., Martins S. B. and Carmo-Fonseca M. (2014) Exploring New Therapeutic Approaches for Hypertrophic Cardiomyopathy. HEART WITH/OUT BORDERS– cardiovascular development, disease & repair, International Conference, Porto, Portugal. 28-29th November 2014.". Paper presented in HEART WITH/OUT BORDERS– cardiovascular development, disease & repair, International Conference, Porto, Portu, 2014.
  5. Carvalho, Teresa. "Mendes de Almeida R., Carvalho T., Martins S., Carmo-Fonseca M. (2013). Exploring New Therapeutic Approaches for Hypertrophic Cardiomyopathy".7th PhD Student Meeting, IMM, Lisbon, Portugal. 5-6th December 2013.". 2013.
  6. Carvalho, Teresa. "Carvalho T., Martins S. B. and Carmo-Fonseca M. Poster presentation entitled: “Non productive.(2012). Spliceosome assembly is sufficient to export unspliced RNA to the cytoplasm”. EMBL/EMBO Symposium "The complex life of mRNA", EMBL, Heidelberg, Germany. 7-10 October 2012.". 2012.
  7. Carvalho, Teresa. "Mendes de Almeida R., Freitas, A.C., Carvalho T., Martins S. B. and Carmo-Fonseca M. (2012). A novel RNA based therapy to Hypertrophic Cardiomyopathy. FEBS RNA Workshop, Tavira, Portugal. 1-4 September 2012.". 2012.
  8. Carvalho, Teresa. "Marinho S., Carvalho T., Martins S. B. and Carmo-Fonseca M. (2012). Comparative analysis of cDNA synthesis kits. FEBS RNA Workshop, Tavira, Portugal. 1-4 September 2012.". 2012.
  9. Carvalho, Teresa. "Carvalho T., Martins S. B. and Carmo-Fonseca M. Portugal. (2012). Non productive spliceosome assembly is sufficient to export unspliced RNA to the cytoplasm. FEBS RNA Workshop, Tavira, Portugal. 1-4 September 2012.". 2012.
  10. Carvalho, Teresa. "Mendes de Almeida, R., Carvalho, T., Martins, S. and Carmo-Fonseca M. (2012). A novel RNA based Therapy to Hypertrophic Cardiomyopathy. Portuguese RNA Meeting, Lisbon, Portugal. 26-27th January 2012,". 2012.
  11. Carvalho, Teresa. "Marinho, S., Carvalho,T., Martins,S. and Carmo-Fonseca M. (2012). cDNA Synthesis Kits: Which, When and Why. Portuguese RNA Meeting, Lisbon, Portugal. 26-27th January 2012, Lisbon, Portugal.". 2012.
  12. Carvalho, Teresa. "Martins S., Carvalho T., Carvalho C. and Carmo-Fonseca M. (2010). The splicing inhibitor Spliceostatin A induces accumulation of unspliced transcripts in nuclear speckles. Nuclear Organization and Function, Cold Spring Harbor Symposium. 2-7 June 2010, CSH, NY, USA.". 2010.
  13. Carvalho, Teresa. "Carvalho T., Martins S., Rino J., Carvalho C., Braga J. and Carmo-Fonseca M. (2010). Imaging spliceosome assembly dynamics in live cells. Nuclear Organization and Function, Cold Spring Harbor Symposium. 2-7 June 2010, CSH, NY, USA.". 2010.
  14. Carvalho, Teresa. "Carvalho T., Martins S., Rino J., Carvalho C., Braga J., Almeida S. and Carmo-Fonseca M. Splicing affects in vivo dynamics of pre mRNA transcription.(2009) EMBO Conference, Nuclear Structure and Dynamics.September 30-October 4 2009, L´Isle sur la Sorgue, France.". 2009.
  15. Carvalho, Teresa. ". J. E. Fonseca, J. Cavaleiro, J. Teles, E. Sousa, V. L. Andreozzi, M. Antunes, M. A. Turkman, H. Canhao, A. F. Mourao, J. Lopes, J. Caetano-Lopes, P.Weinmann, M. Sobral, P. Nero, M. J.Saavedra, A. Malcata, M. Cruz, R. Melo, A. Brana, L. Miranda, J. V. Patto, A. Barcelos, J. Canas da Silva, L. Santos, G.Figueiredo, M. Rodrigues, H. Jesus, A. Quintal, T. Carvalho, J. A.Pereira da Silva, J. Branco,". 2007.
  16. Carvalho, Teresa. "Carvalho T, Rino J, Braga J, Luhrmann R, Carmo-Fonseca M. (2006). Intranuclear Trafficking of Splicing snRNPs. Dynamic Organization of Nuclear Function. Cold Spring Harbor NY, September 27-October 1, 2006.". 2006.
  17. Carvalho, Teresa. "Engenheiro EL, Carvalho T, Marques Ramos L, Kalscheuer V, Tummer Z, Carmo-Fonseca M, Tommeruf N. (2005). Reduced Cajal body number in a patient haploinsufficient for coilin. European Society of Human Genetics ESHG, May, 7-10 2005.". 2005.
  18. Carvalho, Teresa. "Sobral M, Fonseca JE, Mourão AF, Cruz M, Nero P, Cavaleiro J, Carvalho T, Canhão H, Costa MM, Castelão W, Macieira C, Miranda L, Santos SA, Laudim E, Costa RP, Vaz Patto J, Canas da Silva J, Pereira da Silva JA, Viana Queiroz M, Branco JC, Carmo Fonseca M (2004). Polimorfismo -308 do Gene do Factor de Necrose Tumoral Alfa e Artrite Reumatóide: Potencial Relação com Actividade da Doença - Análise P". 2004.
  19. Carvalho, Teresa. ". Cavaleiro J, Fonseca JE, Mourão AF, Sobral M, Cruz M, Carvalho T, Canhão H, Costa MM, Castelão W, Macieira C, Santos SA, Laudim E, Costa RP, Canas da Silva J, Pereira da Silva JA, Viana Queiroz M, Branco JC, Carmo Fonseca M (2004). Polymorphism at position -238 of the tumor necrosis factor alpha and rheumatoid arthritis: prognosis and pharmacogenetics- interim analysis. 5th Annual EULAR Congress". 2004.
  20. Carvalho, Teresa. "Gama-Carvalho M, Custódio N, Carvalho C, Carvalho T e Ferreira J. (2002). Teaching molecular biology to medical students – simulating a biomedical research Project. Poster apresentado no Encontro anual da AMEE, Lisboa 29 de agosto a 1 de setembro de 2002.". 2002.
Journal article
  1. Ribeiro, Marta; Martins, Sandra; Carvalho, Teresa; Furtado, Marta; Sampaio Cabral, Joaquim; Brito, Dulce; Carmo-Fonseca, Maria; da Rocha, Simão Teixeira. "Generation of induced pluripotent stem cell lines from two unrelated individuals with familial hypertrophic cardiomyopathy carrying the MYBPC3 missense c.1484G>A mutation". Stem Cell Research 74 (2024): 103282. http://dx.doi.org/10.1016/j.scr.2023.103282.
    10.1016/j.scr.2023.103282
  2. Ribeiro, Marta; Furtado, Marta; Martins, Sandra; Carvalho, Teresa; Carmo-Fonseca, Maria. "RNA Splicing Defects in Hypertrophic Cardiomyopathy: Implications for Diagnosis and Therapy". International Journal of Molecular Sciences 21 4 (2020): 1329. http://dx.doi.org/10.3390/ijms21041329.
    10.3390/ijms21041329
  3. Carvalho, Teresa; Martins, Sandra; Rino, José; Marinho, Sérgio; Carmo-Fonseca, Maria. "Pharmacological inhibition of the spliceosome subunit SF3b triggers exon junction complex-independent nonsense-mediated decay". Journal of Cell Science 130 9 (2017): 1519-1531. http://dx.doi.org/10.1242/jcs.202200.
    10.1242/jcs.202200
  4. Mendes de Almeida, Rita; Tavares,J; Martins, Sandra Bento; Carvalho, Teresa; Enguita, Francisco J.; Brito, Dulce; Carmo-Fonseca, M; Lopes Luis R. "Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy". PloS One, 12 8 (2017):
    Published
  5. Mendes de Almeida R; Tavares J; Martins S; Carvalho T; Enguita FJ; Brito D; Carmo-Fonseca M; Lopes LR. "Whole gene sequencing identifies deep-intronic variants with potential functional impact in patients with hypertrophic cardiomyopathy.". PloS one (2017): http://europepmc.org/abstract/med/28797094.
    10.1371/journal.pone.0182946
  6. Rino, José; Martin, Robert M.; Carvalho, Teresa; Carmo-Fonseca, Maria. "Imaging dynamic interactions between spliceosomal proteins and pre-mRNA in living cells". Methods 65 3 (2014): 359-366. http://dx.doi.org/10.1016/j.ymeth.2013.08.010.
    10.1016/j.ymeth.2013.08.010
  7. Martins, Sandra Bento; Rino, José; Carvalho, Teresa (EC1A-86D9-0436); Carvalho, Célia; Yoshida, Minoru; Klose, Jasmim Mona; de Almeida, Sérgio Fernandes; Carmo-Fonseca, Maria. "Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes". Nature Structural & Molecular Biology 18 10 (2011): 1115-1123. http://dx.doi.org/10.1038/nsmb.2124.
    10.1038/nsmb.2124
  8. Rino, José; Braga, José; Desterro, Joana M.P.; Lührmann, Reinhard; Carmo-Fonseca, Maria. "A Stochastic View of Spliceosome Assembly and Recycling in the Nucleus". PLoS Computational Biology preprint 2007 (2007): e201. http://dx.doi.org/10.1371/journal.pcbi.0030201.eor.
    10.1371/journal.pcbi.0030201.eor
  9. Fonseca, João; Cavaleiro, João; Teles, José; Sousa, Elsa; Andreozzi, Valeska L; Antunes, Marília; Amaral-Turkman, Maria A; et al. "Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter". Arthritis Research & Therapy 9 2 (2007): R37. http://dx.doi.org/10.1186/ar2173.
    10.1186/ar2173
  10. Gama-carvalho Margarida; Joana Desterro; Carvalho, Teresa (EC1A-86D9-0436); Carvalho, Célia; Calado Patrícia; Custódio Noélia. "Invisible Rays:our extraterrestrial enemies? Detecting UV radiation in our environment". Bioscience explained 3 2 (2007):
  11. Rino, J.; Carvalho, T.; Braga, J.; Desterro, J.M.P.; Lührmann, R.; Carmo-Fonseca, M.. "A stochastic view of spliceosome assembly and recycling in the nucleus". PLoS Computational Biology 3 10 (2007): 2019-2031. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748935227&partnerID=MN8TOARS.
    10.1371/journal.pcbi.0030201
  12. Fonseca, J E; Carvalho, Teresa; Cruz, M.; Nero P; Sobral M; Mourao AF; Cavaleiro J,; et al. "Polymorphism at position -308 of the tumour necrosis factor   gene and rheumatoid arthritis pharmacogenetics". Annals of the Rheumatic Diseases 64 5 (2005): 793-794. http://dx.doi.org/10.1136/ard.2004.028167.
    10.1136/ard.2004.028167
  13. Carvalho, Teresa; Almeida, Fátima; Calapez, Alexandre; Lafarga, Miguel; Berciano, Maria T.; Carmo-Fonseca, Maria. "The Spinal Muscular Atrophy Disease Gene Product, Smn". The Journal of Cell Biology 147 4 (1999): 715-728. http://dx.doi.org/10.1083/jcb.147.4.715.
    10.1083/jcb.147.4.715
  14. DING, HAO; DESCHEEMAEKER, KOEN; MARYNEN, PETER; NELLES, LUC; Carvalho, Teresa; CARMO-FONSECA, MARIA; COLLEN, DÉSIRÉ; BELAYEW, ALEXANDRA. "Characterization of a Helicase-Like Transcription Factor Involved in the Expression of the Human Plasminogen Activator Inhibitor-1 Gene". DNA and Cell Biology 15 6 (1996): 429-442. http://dx.doi.org/10.1089/dna.1996.15.429.
    10.1089/dna.1996.15.429
  15. Ding, H.; Descheemaeker, K.; Maryncn, P.; Nellcs, L.; Carvalho, T.; Carmo-Fonseca, M.; Collen, D.; Belayew, A.. "A helicase-Like transcription factor is involved in the basal expression of the human pai-1 gene. II 214". Fibrinolysis 10 SUPPL. 3 (1996): http://www.scopus.com/inward/record.url?eid=2-s2.0-33846666039&partnerID=MN8TOARS.
  16. Carvalho, Teresa; Seeler, J S; Ohman, K; Jordan, P; Pettersson, U; Akusjärvi, G; Carmo-Fonseca, M; Dejean, A. "Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.". The Journal of Cell Biology 131 1 (1995): 45-56. http://dx.doi.org/10.1083/jcb.131.1.45.
    10.1083/jcb.131.1.45
  17. Carvalho, T.; Seeler, J.-S.; Öhman, K.; Jordan, P.; Pettersson, U.; Akusjärvi, G.; Carmo-Fonseca, M.; Dejean, A.. "Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies". Journal of Cell Biology 131 1 (1995): 45-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029100611&partnerID=MN8TOARS.
  18. Weis, Karsten; Rambaud, Sophie; Lavau, Catherine; Jansen, Joop; Carvalho, Teresa; Carmo-Fonseca, Maria; Lamond, Angus; Dejean, Anne. "Retinoic acid regulates aberrant nuclear localization of PML-RARa in acute promyelocytic leukemia cells". Cell 76 2 (1994): 345-356. http://dx.doi.org/10.1016/0092-8674(94)90341-7.
    10.1016/0092-8674(94)90341-7
  19. Carmo-Fonseca, M; Pepperkok, R; Carvalho, Teresa; Lamond, AI. "Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies". The Journal of Cell Biology 117 1 (1992): 1-14. http://dx.doi.org/10.1083/jcb.117.1.1.
    10.1083/jcb.117.1.1
Thesis / Dissertation
  1. Carvalho, Teresa. "Corpos Nucleares: Uma abordagem morfo-funcional". PhD, Universidade de Lisboa Faculdade de Medicina, 2001.
  2. Carvalho, Teresa. "O cancro no estudo da organização morfofuncional do núcleo: A Leucémia aguda Promielocítica como modelo biológico". Master, Universidade de Lisboa Faculdade de Medicina, 1995.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2016/04 Martins, S. and Carvalho, T. (2016) Oral communication entitled: Exploring new therapeutic approaches for hypertrophic cardiomyopathy. Ludwig Maximilian University of Munich PhD. Program. Institute of Molecular Medicine, Lisbon, Portugal. April 2016. Ludwig Maximilian University of Munich PhD. Program
nstitute of Molecular Medicine, Lisbon, Portugal (Lisboa, Portugal)
2009 Martins S., Rino J., Carvalho C., Carvalho T., Braga J., Almeida S. and Carmo-Fonseca, M. (2009). Live-cell imaging reveals cross-talk between spliceosome assembly and RNA Polymerase II dynamics. RNA Meeting 2009, 14th Annual Meeting of the RNA Society, Madison, Wisconsin, USA. 25 May- 1 June 2009. RNA Meeting,
4th Annual Meeting of the RNA Society, Madison, Wisconsin, USA (Wisconsin, United States)
2006 Cavaleiro J, Teles J, Sousa E, Canhão H, Mourão AF, Sobral, M Nero P, Saavedra MJ, Malcata A, Cruz M, Melo R, Braña A, Miranda L, Patto JV, Barcelos A, Silva JC, Santos LM, Figueiredo G, Rodrigues M, Jesus H, Quintal A, Carvalho T, Amaral-Turkman MA, Andreozzi VL, Antunes MJ, Pereira da Silva JA, Branco J, Viana Queiroz M, Fonseca JE (2006). Sequencing of the Tumour Necrosis Factor Alpha gene promoter: contribution for new genetic markers of rheumatoid arthritis activity and severity EULAR 2006, Amsterdam. Annual meeting
EULAR 2006, Amsterdam.
2006 Cavaleiro J, Teles J, Sousa E, Canhão H, Mourão AF, Sobral M, Nero P, Saavedra MJ, Malcata A, Cruz M, Melo R, Braña A, Miranda L, Patto JV, Barcelos A, Canas da Silva J, Santos LM, Figueiredo G, Rodrigues M, Jesus H, Quintal A, Carvalho T, A Amaral-TurkmanM, Andreozzi VL, Antunes MJ, Pereira da Silva JA, Carmo-Fonseca M, Branco J, Viana Queiroz M, Fonseca JE (2006). Sequenciação da região do promotor do Factor de Necrose Tumoral alfa – contribuição para novos marcadores genéticos de actividade e gravidade da artrite reumatóide. reunião Anual-Congresso português de reumatologia
sociedade portuguesa de Reumatologia, (São Miguel, Portugal)
2005 Cavaleiro J, Fonseca JE, Mourão A, Sobral M, Canhão H, Nero P, Cruz M, Miranda L, Vaz Patto J, Canas da Silva J, Santos LM, Figueiredo G, Jesus H, Rodrigues M, Quintal A, Teles J, Carvalho T, Pereira da Silva JA, Branco JC, Viana Queiroz M, Carmo Fonseca M (2005). Are clinical measures of RA activity and severity influenced by the TNFa -238 GG genotype? EULAR 2005, Vienna. Annual meeting-EULAR
EULAR (Viena, Germany)
2004 Mourão AF, Fonseca JE, Sobral M, Cruz M, Nero P, Cavaleiro J, Carvalho T, Canhão H, Costa MM, Castelão W, Macieira C, Miranda L, Santos SA, Laudim E, Costa RP, Vaz Patto J, Canas da Silva J, Pereira da Silva JA, Viana Queiroz M, Branco JC, Carmo Fonseca M (2004). Polimorfismo -238 do Gene do Factor de Necrose Tumoral Alfa e Artrite Reumatóide: Potencial Relevância Prognóstica - Análise Preliminar. XII Congresso Português de Reumatologia, Lisboa, 31 de março a 3 de abril de 2004.
2004 Nero P, Fonseca JE, Cruz M, Sobral M, Mourão AF, Cavaleiro J, Carvalho T, Santos SA, Laudim E, Costa RP, Branco JC, Carmo Fonseca M (2004). Polimorfismo -308 do Gene do Factor de Necrose Tumoral Alfa e Terapêutica com Infliximab na Artrite Reumatóide: Potencial Relação Com Resposta Clínica - Análise Preliminar. XII Congresso Português de Reumatologia, Lisboa, 31 de março a 3 de abril de 2004.
2004 Cavaleiro J, Fonseca JE, Teles J, Mourão AF, Sobral M, Cruz M, Carvalho T, Canhão H, Costa MM, Castelão W, Macieira C, Santos SA, Laudim E, Costa RP, Canas da Silva J, Vaz Patto J, Pereira da Silva JA, Viana Queiroz M, Branco JC, Carmo Fonseca M (2004). Polymorphism at position -238 of the Tumor Necrosis Factor alpha and Rheumatoid Arthritis: Prognosis and pharmacogenetics. SPI XXX Annual Meeting 2004, Oeiras.
2004 Teles J, Fonseca JE, Cavaleiro J, Mourão AF, Sobral M, Cruz M, Carvalho T, Canhão H, Costa MM, Castelão W, Macieira C, Santos SA, Laudim E, Costa RP, Canas da Silva J, Vaz Patto J, Pereira da Silva JA, Viana Queiroz M, Branco JC, Carmo Fonseca M (2004). Polymorphism at position -308 of the Tumor Necrosis Factor alpha and Rheumatoid Arthritis: Prognosis and pharmacogenetics. SPI XXX Annual Meeting 2004, Oeiras.
2004 Fonseca JE, Carvalho T, Cruz M, Nero P, Sobral M, Mourão AF, Cavaleiro J, Carmo Fonseca M, Branco JC (2004). Polymorphism at position -308 of the promoter of the Tumor Necrosis Factor a gene and infliximab therapy in rheumatoid arthritis. ACR/ARHP 68th Annual Scientific Meeting 2004, San António.
1999 Carmo-Fonseca, Carvalho T, Almeida F, Lafarga M, Berciano MT (1999). The Spinal Muscular Atrophy Disease Gene Product (SMN) and the coiled Body. 31st Annual Meeting of the European Society of Human Genetics, Geneva, Switzerland, June 1999.
1998 Carvalho T, Almeida F, Carmo-Fonseca M (1998). The SMN protein is localised in coiled bodies. Meeting on Dynamic Organization of Nuclear Function, Cold Spring Harbor, October 1998.
1994 Carvalho T, Carmo-Fonseca M (1995). Os Corpos ncleares PML e a apoptose. XXX Reunião da Sociedade Portuguesa de Microscopia Electrónica e Biologia Celular, Porto,1995.
1994 Carvalho T, Seeler J, Jordan P, Bridge E, Ohman K, Akusjarvi G, Carmo-Fonseca M, Dejean A (1994). Os Corpos PML são alvo de virus oncogénicos. XXIX Reunião da Sociedade Portuguesa de Microscopia Electrónica e Biologia Celular, Coimbra, 1994.
1993 ICarvalho T, Lamond A, Carmo-Fonseca M (1993). Identificação de um novo compartimento nuclear associado ao Corpo espiralado. XXVIII Reunião da Sociedade Portuguesa de Microscopia Electrónica e Biologia Celular, Oeiras, 1993.
1993 Carvalho T, Dejean A, Lamond A, Carmo-Fonseca M (1993). O oncogene PML codifica uma proteína localizada em corpos nucleares. XXVIII Reunião da Sociedade Portuguesa de Microscopia Electrónica e Biologia Celular, Oeiras, 1993.
1992 Carmo-Fonseca M, Weis K, Carvalho T, Lamond A (1992). Calnucleína uma nova proteína de ligação ao Cálcio localizada em compartimentos discretos do núcleo. XXVII Reunião da Sociedade Portuguesa de Microscopia Electrónica, Oeiras, 1992. XXVII Reunião da Sociedade Portuguesa de Microscopia Electrónica
Sociedade Portuguesa de Microscopia Electrónica (Oeiras, Portugal)
1990 Carvalho T, Abreu F, Carmo-Fonseca M (1990). Imunolocalização do Ag La durante a mitose. XXV Reunião da Sociedade Portuguesa de Microscopia Electrónica, Porto, 1990. XXIV Reunião da Sociedade Portuguesa de Microscopia Electrónica, Coimbra, 1989.
Sociedade Portuguesa de Microscopia Electrónica (Coimbra, Portugal)
1990 Cidadão AJ, Ferreira JA, Carvalho T, David-Ferreira JF (1990). Anticorpos Específicos para pequenos proteoglicanos de Condroitina/ Dermatan Sulfato reconhecem epitopos nucleares em tecidos e células em cultura: Resultados preliminares. XXV Reunião da Sociedade Portuguesa de Microscopia Electrónica, Porto, 1990. XXV Reunião da Sociedade Portuguesa de Microscopia Electrónica, Porto, 1990.
Sociedade Portuguesa de Microscopia Electrónica (Porto, Portugal)
1989 Carmo-Fonseca M, Jarasch ED, Backmann M, Carvalho T, Bentes C, Abreu F (1989). Associação de partículas Ribonucleoproteicas Citoplasmáticas (Ro) com os Filamentos Intermédios. XXIV Reunião da Sociedade Portuguesa de Microscopia Electrónica, Coimbra, 1989. XXIV Reunião da Sociedade Portuguesa de Microscopia Electrónica,
Sociedade Portuguesa de Microscopia Electrónica (Coimbra, Portugal)

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Licenciatura em Ciencias da Nutrição-Biologia Molecular e Celular Licenciatura em Ciencias da Nutrição (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2017 - Current Mestrado em Biologia Evolutiva e do Desenvolvimento-Módulo de Biologia e Tecnologia de Células Estaminais Mestrado em Biologia Evolutiva e do Desenvolvimento (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2009 - Current Mestrado integrado em medicina-Tronco Comum V. a) Oncobiologia Mestrado integrado em medicina (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2007/10 - Current Mestrado integrado em medicina-Módulo I.I - Biologia Molecular, Celular e do Desenvolvimento Humano e Genética Mestrado Integrado em medicina (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2005 - 2009 Licenciatura em microbiologia-Cultura de células Licenciatura em microbiologia (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2006 - 2008 Programa de doutoramento GABBA- módulo RNOMICS Programa Graduado em áreas da Biologia Básica e Aplicada Universidade do Porto, Portugal
2001 - 2006 Licenciatura em Engenharia Biomédica-Anatomia e Histologia Licenciatura em Engenharia Biomédica (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
1996 - 2006 Licenciatura em medicina-Biologia Molecular da Célula Licenciatura em Medicina Universidade de Lisboa Faculdade de Medicina, Portugal
2002 - 2005 Mestrado em Doenças Infecciosas Emergentes- Módulo de Biologia Molecular Mestrado em Doenças Infecciosas Emergentes (Mestrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2002 - 2004 Licenciatura em Biotecnologia International First Level Degree-Job Creation Oriented Biotechnology (Bachelor) Universidade de Lisboa Faculdade de Medicina, Portugal
2002 - 2003 Programa Doutoramento GABBA- Módulo Biologia Celular Programa Graduado em áreas da Biologia Básica e Aplicada (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto, Portugal
2002 - 2003 Mestrado em Biofísica-Módulo de Biologia Celular e Molecular Mestrado em Biofísica (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
1988 - 1996 Licenciatura em Medicina- Biologia Celular Licenciatura em medicina (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal