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João O. Malva is a neuroscientist with research experience in fundamental mechanisms of neuromodulation, neuroprotection, neuroinflammation and neural stem cell-based repair. In the last decade, he strongly invested in neuroscience aspects of ageing and its implications to societal impact. He is the founder of Ageing@Coimbra consortium, a Reference Site of the Innovation Partnership on Active and Healthy Ageing. This strong network activity at regional and european level launched the basis for the negotiation of the admission of the University of Coimbra as a Core Partner of EIT Health. João Malva acted as President of the Portuguese Society for Neuroscience (2007-2011), has acted as a member of the University Senate, Assembly and Scientific Council of the Faculty of Medicine and Institute of Interdisciplinary Research of the University of Coimbra. He is currently elected member of the Parliament of the Municipality of Coimbra.
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Identification

Personal identification

Full name
João Malva

Citation names

  • Malva, João
  • Malva JO
  • João O. Malva

Author identifiers

Ciência ID
ED13-3899-FF98
ORCID iD
0000-0002-5438-4447

Telephones

Telephone
  • 239480029 (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
French Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2009/12/06
Concluded
 Biomedicina (Título de Agregado)
Major in Biomedicina
Universidade de Coimbra Faculdade de Medicina, Portugal
1997
Concluded
 Biologia (Doutoramento)
Major in Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Acção Moduladora do Glutamato Nos Terminais Nervosos do Hipocampo de Rato - Identificação de um Receptor de Cainato na Subregião Ca3" (THESIS/DISSERTATION)
1983/09/01 - 1987/07/31
Concluded
 Biologia (Licenciatura)
Universidade de Coimbra, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2016/01 - Current Coordinating Researcher (Research) Universidade de Coimbra, Portugal
2015 - 2018 Visiting Researcher (Research) Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil
Faculdade de Medicina da Universidade Federal do Ceara, Brazil
2002/03 - 2016/01 Principal Investigator (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
1999/06 - 2002/03 Auxiliary Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
1997/06 - 1999/03 Assistant Professor (University Teacher) Universidade do Minho, Portugal
1989/10 - 1997/06 Assistant (University Teacher) Universidade do Minho, Portugal

Positions / Appointments

Category
Host institution 		Employer
2016 - Current Coordenação ou direção de centro de investigação, departamento ou equivalente Universidade de Coimbra, Portugal
2021/09/01 - 2022/08/31 Member Scientific Council Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2013 - 2015 Organic Unit Sub-director Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

Others

Category
Host institution 		Employer
2020/07/01 - Current Membro de Conselho Científico Universidade de Coimbra, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015 - 2017 Membro de Conselho Científico Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2014 Membra de Assembleia de Faculdade (secretário) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
1997/06/01 - 1997/11/30 Não disponível
PRAXIS XXI/BPD/11786/97
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2019/01/01 - Current Ageing@EITHealth PhD School
20588
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Ongoing
2023/01/01 - 2026/12/31 CHAngeing: Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function
HORIZON-WIDERA-2022-ACCESS-04-01
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
Ongoing
2023/03/12 - 2026/03/11 Desigualdades sócio-espaciais na demência
2022.04684.PTDC
Universidade de Coimbra, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
10.54499/LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 EIT Health Ageing PhD School
...
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
 EIT Health
Ongoing
2020/11/01 - 2022/12/31 Healthy loneliness - Development of a training program for improving QoL of seniors living in loneliness through educational activities
2020-1-ES01-KA204-083167
Principal investigator
Universidade de Coimbra, Portugal
Ongoing
2021/01/01 - 2021/12/31 URBHEALTH: Urbanisation and Health Summer Course and MOOC
210801
Centro de Estudos em Geografia e Ordenamento do Território, Portugal
 EIT Health
Ongoing
2018/07/26 - 2021/07/25 Neurotoxicidade do metilmercúrio nos nichos neurogénicos do cérebro adulto: neurogeneração crónica e declínio cognitivo.
PTDC/MED-TOX/31699/2017
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Neurotoxicity of methylmercury in the neurogenic niches of the adult brain (MercuMemory)
FCT-POCI-01-0145-FEDER-031699
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2020/12/31 Healthy Loneliness
20515
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Ongoing
2020/01/01 - 2020/12/31 MercuMemory: Methylmercury neurotoxicity in adult brain neurogenic niches: chronic neurogeneration and cognitive decline.
POCI-01-0145-FEDER-031699
Concluded
2015/07 - 2020/06 Enhancing Research in Ageing at the University of Coimbra
grant.669088
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
 European Commission
Ongoing
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/01/31 - 2019/12/31 Caregiving and Ageing Reimagined for Europe (CARE)
18256
19156
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Concluded
2018/01/01 - 2019/12/31 Healthy Life Style Quarters for Cities and Citizens (HeaLIQs4Cities)
18036
19142
Researcher
Universidade de Coimbra Faculdade de Medicina, Portugal
 Comissão Europeia
Concluded
2015/06 - 2017/05 Stimulating Innovative Polypharmacy Management in the Elderly (SIMPATHY)
663082
 EU Framework Programme for Research and Innovation Health Demographic Change and Wellbeing
2015/06 - 2016/05 Multidisciplinary Institute for Ageing
grant.664629
Principal investigator
Universidade de Coimbra Faculdade de Medicina, Portugal
 European Commission
2014/04/01 - 2015/09/30 A sabedoria do faminto: modulação por ghrelina da neurogénese e da sua relação com a memória
EXPL/NEU-SCC/1193/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/03/01 - 2015/09/30 Ageing@Coimbra: Um Centro de Co-localização na Rede Europeia de Conhecimento e Inovação para o Envelhecimento Saudável e Ativo
EIT-KIC/IVE/0043/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Administração Regional de Saúde do Centro IP, Portugal

Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2014/04 - 2015/09 Hunger wisdom: ghrelin modulation of adult neurogenesis and its relationship with memory
Provided by PTCRIS: 134218
 Fundação para a Ciência e a Tecnologia, I.P.
2014/03 - 2015/09 Ageing@Coimbra: A Co-location Centre in the European Knowledge and Innovation Network for Active and Healthy Ageing
Provided by PTCRIS: 135805
 Fundação para a Ciência e a Tecnologia, I.P.
2010/05/01 - 2013/12/31 Alimentos Fucncionais para Neuroprotecção: um papel para o Hypericum perforatum
PTDC/AGR-ALI/105169/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Minho, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Universidade Católica Portuguesa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/05 - 2013/12 Functional foods for neuroprotection: a role to Hypericum perforatum (Hyperi-Food)
Provided by PTCRIS: 105169
 Fundação para a Ciência e a Tecnologia, I.P.
2010/02 - 2013/07 NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair
Provided by PTCRIS: 101469
PTDC/SAU-OSM/101469/2008
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Garvan Institute of Medical Research, Australia

Centre Hospitalier Universitaire Vaudois Service de pharmacologie clinique, Switzerland

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/06/30 Regeneração cardíaca com células vasculares embrionárias e uma matriz biomimética
PTDC/SAU-BEB/098468/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/06/30 Papel da comunicação intercelular entre células endoteliais e celulas estaminais neurais na "stemness" e a neurogénese: novos alvos terapeuticos para a reparação cerebral
PTDC/SAU-NEU/101783/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/06 Heart regeneration by embryonic vascular cells and a biomimetic scaffold
Provided by PTCRIS: 98468
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04 - 2013/06 Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies.
Provided by PTCRIS: 101783
 Fundação para a Ciência e a Tecnologia, I.P.
2010/04/01 - 2013/03/31 Histamina versus anti-histamínicos: novos moduladores da neurogénese?
PTDC/SAU-NEU/104415/2008
Provided by PTCRIS: 104415
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/11 - 2010/10 Search for the molecular basis of transthyretin involvement in the biology of the nervous system.
Provided by PTCRIS: 64437
 Fundação para a Ciência e a Tecnologia, I.P.
2007/05/01 - 2010/09/30 Alterações na Microglia e Neurónios do Hipocampo Induzidas por Metanfetamina: Papel das Citocinas Pró-inflamatórias e do Neuropeptídeo Y
PTDC/SAU-FCF/67053/2006
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/05 - 2010/09 Microglial and Neuronal Changes in the Hippocampus Induced by Methamphetamine: Role of Pro-inflammatory Cytokines and Neuropeptide Y
Provided by PTCRIS: 67053
 Fundação para a Ciência e a Tecnologia, I.P.
2007/05/01 - 2010/04/30 Células estaminais da região subventricular na reparação cerebral em epilepsia do lobo temporal
PTDC/SAU-NEU/68465/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/05 - 2010/04 Subventricular zone stem cells as a tool for brain repair in temporal lobe epilepsy
Provided by PTCRIS: 68465
 Fundação para a Ciência e a Tecnologia, I.P.
2005/09 - 2008/08 Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons
Provided by PTCRIS: 58492
POCI/SAU-NEU/58492/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. João O. Malva; Ricardo Moreira; Corte Real Martins, Beatriz; Ramon Raposo; Frederico Pereira; Reinaldo Oriá; Carlos Fontes Ribeiro. "Neuroinflammation and ageing". In Assessments, Treatments and Modelling in Aging and Neurological Disease: The Neuroscience of Aging, edited by Elsevier, 139-151. Academic Press - Elsevier, 2021.
    Published
  2. João O. Malva; Beatriz Martins; Ricardo Moreira; Novo, João Pedro; Frederico C. Pereira; Ramon Raposo; Reinaldo oriá; Fontes Ribeiro CA. "Neuroinflammation in the elderly". In Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging, edited by Colin Martin; Victor Preedy; Rajkumar Rajendram, 139-148. Londres, United Kingdom: Academic Press - Elsevier, 2021.
    Published
  3. Pinto, A; Veríssimo, M.; Malva, João. Corresponding author: Pinto, A. "Patologia Cardíaca Crónica no Idoso". In Manual do Cuidador - Envelhecimento Ativo e Saudável. Coimbra, Portugal: Imprensa da Universidade de Coimbra, 2019.
    Published
  4. Malva JO. "Neurogénese e Terapia Celular do Cérebro". In Neurociências, edited by Rego AC; Duarte CB; Oliveira CR, 641-662. Portugal: Lidel, 2017.
    Published
  5. Valero, Jorge; Eiriz, Maria Francisca; Santos, Tiago; Neiva, Ismael; Ferreira, Raquel; Malva, João O.. "Microglia: The Bodyguard and the Hunter of the Adult Neurogenic Niche". In Advances in Stem Cell Research, 245-279. Humana Press, 2012.
    Published • 10.1007/978-1-61779-940-2_14
  6. Grade, Sofia; Agasse, Fabienne; Bernardino, Liliana; Malva, João O.. "Functional Identification of Neural Stem Cell-Derived Oligodendrocytes". In Methods in Molecular Biology, 165-178. Humana Press, 2012.
    10.1007/978-1-61779-815-3_11
  7. Malva JO. "Inflammation and neurogenesis". In Encyclopedia of Neuroscience, 2676-2680. Heidelberg, Germany: Springer, 2008.
    Published
  8. Malva, João O.; Bernardino, Liliana. "Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death". In Interaction Between Neurons and Glia in Aging and Disease, 3-35. Springer US, 2007.
    10.1007/978-0-387-70830-0_1
  9. Agasse, Fabienne; Bernardino, Liliana; Malva, João O.. "Subventricular Zone Cells as a Tool for Brain Repair". In Interaction Between Neurons and Glia in Aging and Disease, edited by Malva JO, 81-108. Springer US, 2007.
    10.1007/978-0-387-70830-0_4
Conference abstract
  1. Fonseca, Élisa; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Pereira, Frederico; Oriá, Reinaldo B.; Fontes Ribeiro C; João O. Malva. "Necrotic-like BV-2 Microglial cell death induced by acute exposure to Methylmercury". Paper presented in FENS Forum 2022, Paris, 2022.
    Submitted
  2. Fonseca, Élisa; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Sardão, Vilma; Oliveira, Paulo; Pereira, Frederico; et al. "BV-2 Microglial cell death induced by acute exposure to Methylmercury". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI 2022), Bari, 2022.
    Submitted
  3. Fernandez-Llimos, Fernando; Figueiredo, Isabel V.; Castel-Branco, Margarida; Cardoso, Filipa L.; Veríssimo, Manuel; Ribeiro, Carlos F.; Malva, João. "SIMPATHY Consortium. Polypharmacy and Adherence: Key Components of Integrated Care: The case of Portugal". Paper presented in 16th International Conference on Integrated Care (ICIC16), Barcelona, 2016.
    Published
  4. Castel-Branco, Margarida; Caramona, M. Margarida; Malva, João; Veríssimo, Manuel; Fernandez-Llimos, Fernando; Figueiredo, Isabel V.; Caramona, Margarida; et al. "Contribution to creating a Good Practice Guideline for home visits to isolated polypharmacy elderly". Paper presented in 9th PCNE Working Conference, Mechelen, 2015.
    Published
  5. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann AS; Ferro ES; et al. "Hemopressin promotes oligodendrogenesis in murine subventricular zone cell cultures". Paper presented in 24th Biennial Meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, Cancún, 2013.
    Published • 10.1111/jnc.12186
  6. Xapelli S; Agasse F; Bernardino L; Schitine CS; Heimann AS; Ferro ES; De Melo Reis RA; Malva JO. "Hemopressin promotes neurogenesis and oligodendrogenesis in murine subventricular zone cell cultures". Paper presented in Neuroscience 2012 (SfN Meeting), New Orleans, 2012.
    Published
  7. Xapelli S; Sardà-Arroyo L; Bernardino L; Santos T.; Schitine CS; Agasse F; Malva JO. "(R)-(+)-Methanandamide stimulates neurogenesis in neural stem/progenitor cell cultures derived from postnatal rodent subventricular zone". Paper presented in FENS Forum 2012, Barcelona, 2012.
    Published
  8. Xapelli S; Sarda L; Bernardino L; Santos T.; Agasse F; Malva JO. "Activation of the cannabinoid CB1 receptor promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures". Paper presented in 10th European Meeting on Glial Cells in Health and Disease, Prague, 2011.
    Published • 10.1002/glia.21210
  9. Xapelli S; Bernardino L; Cortes L; Schitine CS; Ferro ES; De Melo Reis RA; Agasse F; Malva JO. "Type 1 Cannabinoid Receptor Activation Induces Neuronal Differentiation of Subventricular Zone Stem/Progenitor Cell Cultures". Paper presented in 18th Biennial Meeting of the International Society for Developmental Neuroscience, Estoril, 2010.
    Published • 10.1016/j.ijdevneu.2010.07.075
  10. Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine is a Proneurogenic Factor on Subventricular Zone Stem/Progenitor Cells: A New Approach for Brain Repair Therapies". Paper presented in 18th Biennial Meeting of the International Society for Developmental Neuroscience, Estoril, 2010.
    Published • 10.1016/j.ijdevneu.2010.07.074
  11. Xapelli S; De Melo Reis RA; Schitine CS; Cortes L; Heimann AS; Ferro ES; Agasse F; Bernardino L; Malva JO. "Cannabinoid type 1 receptor-mediated modulation of murine subventricular zone neurogenesis". Paper presented in Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Published
  12. Xapelli S; Bernardino L; Cortes L; Schitine CS; De Melo Reis RA; Agasse F; Malva JO. "Type 1 cannabinoid receptor (CB1R) activation promotes neuronal differentiation in murine subventricular zone cell cultures". Paper presented in FENS Forum 2010, Amsterdão, 2010.
    Published
  13. Malva JO; Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.. "Histamine-releasing PLGA microparticles promote neuronal differentiation from neural stem cell cultures". Paper presented in Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Published
  14. Schitine CS; Agasse F; Xapelli S; Silva AP; Reis RAM; De Mello FG; Malva JO. "Ampakines as proneurogenic modulators in murine subventricular zone cell cultures". Paper presented in Neuroscience 2010 (SfN Meeting), San Diego, 2010.
    Published
  15. Bernardino L; Eiriz MF; Xapelli S; Grade S; Rosa A.; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine promotes neurogenesis in subventricular zone cell cultures: a new approach for brain repair therapies". Paper presented in FENS Forum 2010, Amsterdão, 2010.
    Published
  16. Bernardino L; Eiriz MF; Xapelli S; Grade S; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine released from biocompatible microparticles induce neurogenesis in the murine subventricular zone". Paper presented in Neuroscience 2009 (SfN Meeting), Chicago, 2009.
    Published
  17. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Salgado JR; Cavadas C; et al. "Neuroprotective interactions between neuropeptide Y and brain-derived neurotrophic factor: a role for microglia". Paper presented in FENS Forum 2008, Génova, 2008.
    Published
  18. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Cavadas C; Grouzmann E; et al. "Interaction between neurons and microglia in NPY and BDNF-mediated neuroprotection against excitotoxicity". Paper presented in Neuroscience 2007 (SfN Meeting), San Diego, 2007.
    Published
  19. Xapelli S; Bernardino L; Silva AP; Cavadas C; Grouzmann E; Poulsen FR; Jakobsen B; et al. "NPY triggers neuroprotection mechanisms following excitotoxic insults in mouse organotypic hippocampal slice cultures". Paper presented in Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Published
  20. Silva AP; Xapelli S; Ferreira R.; Bernardino L; Pinheiro PS; Zimmer J; Oliveira CR; Malva JO. "Activation of neuropeptide Y1 or Y2 receptors can prevent the excitotoxicity induced by kainate in rat organotypic hippocampal slice cultures". Paper presented in Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Published
  21. Vezzani A; Bernardino L; Xapelli S; Silva AP; Poulsen FR; Jakobsen B; Oliveira CR; Zimmer J; Malva JO. "Distinct tumor necrosis factor-alpha (TNF-a) receptor subtypes modulate neuronal survival to excitotoxic injury in mouse organotypic hippocampal slice cultures". Paper presented in Neuroscience 2005 (SfN Meeting), Washington, 2005.
    Published
  22. Xapelli S; Silva AP; Pinheiro PS; Cavadas C; Jakobsen B; Zimmer J; Grouzmann E; Oliveira CR; Malva JO. "Up-regulation of neuropeptide Y2 receptors and Neuropetide Y levels following kainate injection in rats". Paper presented in FENS Forum 2004, Lisboa, 2004.
    Published
  23. Silva AP; Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Oliveira CR; Malva JO; Zimmer J. "Neuroprotection and decreased of brain derived neurotrophic factor expression mediated by neuropeptide Y2 receptor activation in mouse organotypic hippocampal slice cultures". Paper presented in Neuroscience 2004 (SfN Meeting), San Diego, 2004.
    Published
  24. Malva JO; Bernardino L; Xapelli S; Silva AP; Jakobsen B; Poulsen FR; Oliveira CR; Zimmer J. "Activation of microglia in excitotoxic lesions in organotypic slice cultures of the mouse hippocampus". Paper presented in Neuroscience 2004 (SfN Meeting), San Diego, 2004.
    Published
  25. Bernardino L; Xapelli S; Poulsen FR; Jakobsen B; Zimmer J; Duarte EP; Malva JO. "Effect of Tumor necrosis factor-alpha and Interleukin-1 beta in AMPA-mediated neuronal death in mouse organotypic hippocampal slice cultures". Paper presented in FENS Forum 2004, Lisboa, 2004.
    Published
  26. Silva AP; Xapelli S; Cavadas C; Ffrench-Mullen JM; Oliveira CR; Malva JO. "Modulation of glutamate release and expression of neuropeptide Y receptors in epileptic rats". Paper presented in Neuroscience 2003 (SfN Meeting), New Orleans, 2003.
    Published
Conference poster
  1. Élisa Fonseca; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Frederico C. Pereira; Reinaldo B. Oriá; Carlos Fontes-Ribeiro; João O. Malva. "Neurotoxicity and molecular effects of acute Methylmercury exposure in Microglial Cells". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  2. Élisa Fonseca; Novo, João Pedro; Corte Real Martins, Beatriz; Raposo, Ramon; Frederico C. Pereira; Reinaldo B. Oriá; Fontes Ribeiro C; João O. Malva. "Acute Methylmercury exposure induces Neurotoxicity and Microglial Cell Death". Paper presented in V Symposium Portuguese Glial Network 2021, 2021.
  3. Novo, João Pedro; Beatriz Martins; Ramon Raposo; Frederico C. Pereira; Reinaldo Oriá; João O. Malva; Fontes Ribeiro CA. "The Effect Of Methylmercury On Microglia Inflammatory Responses". Paper presented in SPF Meeting 2021, 2021.
  4. Beatriz Martins; Novo, João Pedro; Ricardo Moreira; Ramon Raposo; Frederico C. Pereira; Reinaldo Oriá; João O. Malva; Fontes Ribeiro CA. "The Impact Of Methylmercury On Microglia-Derived Neuroinflammation And Neurogenesis". Paper presented in I International CAPES Print Symposium in Neurosciences and III Simpósio Luso-Brasileiro de Neurociências, 2020.
  5. Beatriz Martins; Novo, João Pedro; João O. Malva; Fontes Ribeiro CA; Ana Paula Pereira da Silva Martins; Frederico Pereira; Reinaldo oriá. "Mercumemory: the effect of methylmercury exposure in microglia-mediated neuroinflammation". Paper presented in XIV European Meeting on Glial Cells in Health and Disease, 2019.
  6. Beatriz Martins; Novo, João Pedro; Ana Paula Pereira da Silva Martins; Frederico Pereira; Reinaldo oriá; Fontes Ribeiro CA; João O. Malva. "Unraveling the effect of methylmercury exposure in neuroinflammation and neurogenesis". Paper presented in Sociedade Portuguesa de Neurociências Meeting, 2019.
  7. Martins, Beatriz; João O. Malva; Fontes Ribeiro CA; Pereira, Frederico. "UNRAVELING THE EFFECT OF METHYLMERCURYEXPOSURE IN NEUROINFLAMMATION". Paper presented in XIV European Meeting on Glial Cells in Health and Disease., 2018.
  8. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann A; Ferro ES; et al. "Induction of oligodendrogenesis by hemopressin in subventricular zone neural stem cell cultures". Paper presented in ISN/ FENS School 2013, Kolymbari, Creta, Grécia, 2013.
  9. Xapelli S; Agasse F; Ribeiro FF; Bernardino L; Schitine CS; Heimann A; Ferro ES; et al. "Hemopressin as a regulator of oligodendrogenesis in neural stem cell cultures from the subventricular zone". Paper presented in EMBO Young Scientists¿ Forum, Lisboa, Portugal, 2013.
  10. Xapelli S; Sardà L; Bernardino L; Santos T.; Schitine CS; Cortes L; De Melo Reis RA; et al. "The endocannabinoid system promotes proliferation and neuronal differentiation in murine subventricular zone cell cultures". Paper presented in 8th World congress of IBRO, Florença, Itália, 2011.
  11. Xapelli S; De Melo Reis RA; Bernardino L; Agasse F; Schitine CS; Cortes L; Heimann A; Ferro ES; Malva JO. "Endocannabinoids mediate neurogenesis in murine subventricular zone Stem/Progenitor Cell Cultures". Paper presented in 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (SPCE-TC), Biocant-Cantanhede, Portugal, 2011.
  12. Bernardino L; Eiriz MF; Santos T.; Xapelli S; Grade S; Rosa A; Cortes L; et al. "Histamine as a promising proneurogenic factor on subventricular zone stem cells: a new approach for brain repair". Paper presented in 8th World congress of IBRO, Florença, Itália, 2011.
  13. Santos T.; Ferreira R.; Maia J; Xapelli S; Cortes L; Agasse F; Bragança J; et al. "Neuronal differentiation of neural stem cells by a novel retinoic acid-loaded nanoparticles delivery system". Paper presented in 8th World congress of IBRO, Florença, Itália, 2011.
  14. Santos T.; Ferreira R.; Maia J; Xapelli S; Cortes L; Agasse F; Bragança J; et al. "Retinoic Acid-Loaded Nanoparticles Induce Neuronal Differentiation of Neural Stem cells". Paper presented in 12th Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, Portugal, 2011.
  15. Bernardino L; Eiriz MF; Santos T.; Xapelli S; Grade S; Rosa A; Cortes L; et al. "Histamine as a proneurogenic factor on subventricular zone: a new approach for brain repair therapies". Paper presented in 12th Meeting of the Portuguese Society for Neuroscience (SPN), Lisboa, Portugal, 2011.
  16. Xapelli S; Bernardino L; Cortes L; Schitine CS; Ferro ES; De Melo Reis RA; Agasse F; Malva JO. "Activation of type 1 cannabinoid receptor (CB1R) induce neurogenesis in the murine subventricular zone". Paper presented in International Symposium: Stem Cells in Biology and Disease (Estools), Lisboa, Portugal, 2010.
  17. Eiriz MF; Bernardino L; Xapelli S; Grade S; Rosa A; Cortes L; Agasse F; Ferreira L.; Malva JO. "Histamine-releasing PLGA microparticles as a tool to impel brain repair". Paper presented in International Symposium: Stem Cells in Biology and Disease (Estools), Lisboa, Portugal, 2010.
  18. Schitine CS; Agasse F; Xapelli S; Silva AP; De Melo Reis RA; De Mello FG; Malva JO. "AMPA and ampakines as proneurogenic modulators of progenitors derived from subventricular zone". Paper presented in FeSBE 2009, XXIV Annual Meeting, São Paulo, Brasil, 2009.
  19. Xapelli S; Bernardino L; Ferreira R.; Grade S; Silva AP; Cavadas C; Grouzmann E; et al. "Interactions between NPY and BDNF in neuroprotection against excitotoxicity: a role for neuron-microglia crosstalk?". Paper presented in 10th Meeting of the Portuguese Society for Neuroscience (SPN), Ofir, Portugal, 2007.
  20. Cristóvão AJ; Xapelli S; Ferreira R.; Silva B; Grade S; Pinheiro PS; Malva JO. "Zinc in excitotoxic injury in rat hippocampus: role of AMPA and kainate receptors in zinc-induced neuronal and glial cell death". Paper presented in International Society for Zinc Biology Meeting, Siena, Itália, 2006.
  21. Xapelli S; Hamilton T; Malva JO; Colmers WF. "NPY modulation of Backpropagation-Activated Calcium Currents (BAC) of neocortical layer 5 pyramidal cells". Paper presented in Bordeaux PENS Training Center, European Synapse Summer School, Bordeaux, França, 2006.
  22. Xapelli S; Bernardino L; Silva AP; Salgado JR; Cavadas C; Grouzmann E; Poulsen FR; et al. "Implication of BDNF in the neuroprotective effect of NPY in mouse hippocampal slice cultures exposed to excitotoxic insults". Paper presented in 8th International NPY meeting, St. Petersburg, Estados Unidos, 2006.
  23. Pinheiro PS; Xapelli S; Ferreira R.; Cristóvão AJ; Malva JO. "Zinc in excitotoxic injury of CA3 pyramidal neurons of the rat hippocampus: effect on AMPA and kainate receptors at postsynaptic and presynaptic sites". Paper presented in 9th International Symposium on Metal Ions in Biology and Medicine, Lisboa, Portugal, 2006.
  24. Silva AP; Lourenço J; Xapelli S; Ferreira R.; Oliveira CR; Kristiansen H; Woldbye DP; Malva JO. "Cross-talk between neuropeptide Y and PKC in the modulation of glutamate release in the hippocampus of kainate-induced epileptic rats". Paper presented in 8th International NPY meeting, St. Petersburg, Estados Unidos, 2006.
  25. Álvaro, Ana Rita ; Raquel Santiago; Pereira, Ana Paula da Silva; Joao O. Malva; Eric Grouzmann; Ana Luísa Carvalho; António F. Ambrósio; et al. "Neuropeptide Y Receptors Modulate [Ca2+]i Changes In Retinal Neural Cells". Paper presented in The Association for Research in Vision and Ophthalmology¿ (ARVO), 2005.
  26. Xapelli S; Silva AP; Ferreira R.; Bernardino L; Pinheiro P; Zimmer J; Oliveira CR; Malva JO. "NPY Y1 and Y2 receptors activation can rescue neurons following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures". Paper presented in Neuro-glia Interaction in Aging and Disease (FENS/Blackwell Summer School), Ofir, Portugal, 2005.
  27. Lourenço J; Xapelli S; Oliveira CR; Malva JO; Silva AP. "Involvement of Protein Kinase C in the modulation of glutamate release mediated by neuropeptide Y2 receptors in the hippocampus of epileptic rats". Paper presented in Neuro-glia Interaction in Aging and Disease (FENS/Blackwell Summer School), Ofir, Portugal, 2005.
  28. Silva AP; Lourenço J; Xapelli S; Oliveira CR; Malva JO. "Protein kinase C signalling is involved in the modulation of glutamate release mediated by neuropeptide Y2 receptors in the hippocampus of epileptic rats". Paper presented in 9th Annual meeting of The Portuguese Society for Neuroscience, Luso, Portugal, 2005.
  29. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "A activação do receptor Y2 do NPY protege culturas organotípicas de hipocampo de murganho contra agressões excitotóxicas". Paper presented in IV Congress of Research in Medicine, Coimbra, Portugal, 2004.
  30. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "Neuropeptide Y2 receptor activation protect mouse organotypic hippocampal slice cultures against excitotoxic insults". Paper presented in 3rd INMED/TINS Conference (The multiple facets of Gabaregic synapses), La Ciotat, França, 2004.
  31. Xapelli S; Bernardino L; Poulsen FR; Jakobsen B; Zimmer J; Malva JO. "Effect of neuropeptide Y2 receptor activation in AMPA-mediated neuronal death and Brain Derived Neurotrophic Factor expression in mouse organotypic hippocampal slice cultures". Paper presented in New molecular stratagies to treat neurodegenerative diseases (FEBS advanced course), Ofir, Portugal, 2004.
  32. Xapelli S; Silva AP; Bernardino L; Jakobsen B; Zimmer J; Oliveira CR; Malva JO. "Neuroprotection by neuropeptide Y activation in excitotoxicity and epilepsy". Paper presented in Brain Damage Repair, Lisboa, Portugal, 2004.
  33. Xapelli S; Bernardino L; Silva AP; Jakobsen B; Zimmer J; Malva JO. "Activation of neuropeptide Y2 and Y5 receptor is neuroprotective against excitotoxicity induced by AMPA in mouse organotypic hippocampal slice cultures". Paper presented in 7th International NPY meeting, Coimbra, Portugal, 2004.
  34. Malva JO; Silva AP; Xapelli S; Pinheiro PS; Cavadas C; Oliveira CR. "Modulation of presynaptic excitability by kainate and NPY receptors in the rat hippocampus: relevance for epileptogenesis and neuroprotection". Paper presented in 1st Neuroscience Symposium, Natal, Brasil, 2004.
  35. Silva AP; Xapelli S; Oliveira CR; Malva JO. "Functional interaction between NPY receptors and modulation of glutamate release in control and epileptic rat hippocampus". Paper presented in 1st Neuroscience Symposium, Natal, Brasil, 2004.
  36. Xapelli S; Bernardino L; Silva AP; Poulsen FR; Jakobsen B; Oliveira CR; Malva JO; Zimmer J. "Involvement of neuropeptide Y2 receptor in neuroprotection and decrease of Brain Derived Neurotrophic Factor expression under excitotoxicity in mouse organotypic hippocampal slice cultures". Paper presented in XIV Meeting of Portuguese Biochemical Society, Vilamoura, Portugal, 2004.
  37. Xapelli S; Silva AP; Pinheiro PS; Cavadas C; Oliveira CR; Malva JO. "Sub-cellular synaptic distribution of NPY Y2 and Y5 receptor subtypes and NPY levels in rat hippocampal subregions". Paper presented in 8th Annual meeting of The Portuguese Society for Neuroscience, Curia, Portugal, 2003.
  38. Silva AP; Xapelli S; Oliveira CR; Malva JO. "Modulation of glutamate release by neuropeptide Y receptors activation in hippocampal nerve terminals of control and epileptic rats". Paper presented in 8th Annual meeting of The Portuguese Society for Neuroscience, Curia, Portugal, 2003.
Edited book
  1. Aging. Aging: from Fundamental Biology to Societal Impact. Elsevier. 2023.
    10.1016/c2020-0-00576-1 • Editor
  2. Pinto, Anabela Mota; Veríssimo, Manuel; Malva, João. Manual do Cuidador. Imprensa da Universidade de Coimbra. 2019.
    10.14195/978-989-26-1851-7
  3. Santana, Paula (ed.). Atlas of population health in European Union regions. Imprensa da Universidade de Coimbra. 2017.
    10.14195/978-989-26-1463-2
  4. Malva JO. Polypharmacy Management by 2030: a patient safety challenge. Coimbra, Portugal. 2017.
    Published • Editor
  5. Malva JO. Interaction Between Neurons and Glia in Aging and Disease. Springer US. 2007.
    10.1007/978-0-387-70830-0
Journal article
  1. Reinaldo B. Oriá; Raul S. Freitas; Cássia R. Roque; José Carlos R. Nascimento; Ana Paula Silva; João O. Malva; Richard L. Guerrant; Michael P. Vitek. "ApoE Mimetic Peptides to Improve the Vicious Cycle of Malnutrition and Enteric Infections by Targeting the Intestinal and Blood-Brain Barriers". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15041086.
    10.3390/pharmaceutics15041086
  2. Tyciane S. Nascimento; Daniel V. Pinto; Ronaldo pereira dias; Ramon S. Raposo; Paulo Iury Gomes Nunes; Cássia R. Roque; Flavia Santos; et al. "Chronic Methylmercury Intoxication Induces Systemic Inflammation, Behavioral, and Hippocampal Amino Acid Changes in C57BL6J Adult Mice". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/22/13837.
    10.3390/ijms232213837
  3. Azul, Anabela Marisa; Almendra, Ricardo; Quatorze, Marta; Loureiro, Adriana; Reis, Flávio; Tavares, Rui; Mota-Pinto, Anabela; et al. "Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study". BMC Public Health 21 1 (2021): http://dx.doi.org/10.1186/s12889-021-11661-4.
    10.1186/s12889-021-11661-4
  4. Leocádio, Paola Caroline L.; Lopes, Synara C.; Dias, Ronaldo P.; Alvarez-Leite, Jacqueline I.; Guerrant, Richard L.; Malva, João O.; Oriá, Reinaldo B.. "The Transition From Undernutrition to Overnutrition Under Adverse Environments and Poverty: The Risk for Chronic Diseases". Frontiers in Nutrition 8 (2021): http://dx.doi.org/10.3389/fnut.2021.676044.
    10.3389/fnut.2021.676044
  5. Novo, João P.; Martins, Beatriz; Raposo, Ramon S.; Pereira, Frederico C.; Oriá, Reinaldo B.; Malva, João O.; Fontes-Ribeiro, Carlos. "Cellular and Molecular Mechanisms Mediating Methylmercury Neurotoxicity and Neuroinflammation". International Journal of Molecular Sciences 22 6 (2021): 3101. http://dx.doi.org/10.3390/ijms22063101.
    10.3390/ijms22063101
  6. Raposo RDS; Pinto DV; Moreira R; Dias RP; Fontes Ribeiro CA; Oriá RB; Malva JO. "Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?". Frontiers in aging neuroscience (2020): http://europepmc.org/abstract/med/33328968.
    10.3389/fnagi.2020.591601
  7. Pinto DV; Raposo RS; Matos GA; Alvarez-Leite JI; Malva JO; Oriá RB. "Methylmercury Interactions With Gut Microbiota and Potential Modulation of Neurogenic Niches in the Brain.". Frontiers in neuroscience (2020): http://europepmc.org/abstract/med/33224022.
    10.3389/fnins.2020.576543
  8. Bousquet J; Anto JM; Bachert C; Haahtela T; Zuberbier T; Czarlewski W; Bedbrook A; et al. "ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.". Allergy (2020): http://europepmc.org/abstract/med/32512619.
    10.1111/all.14422
  9. Oriá RB; Empadinhas N; Malva JO. "Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System.". Frontiers in immunology (2020): http://europepmc.org/abstract/med/32849628.
    10.3389/fimmu.2020.01758
  10. Cortes L; Malva J; Rego AC; Pereira CF. "Calcium Signaling in Aging and Neurodegenerative Diseases 2019.". International journal of molecular sciences (2020): http://europepmc.org/abstract/med/32046230.
    10.3390/ijms21031125
  11. Santana P; Freitas Â; Stefanik I; Costa C; Oliveira M; Rodrigues TC; Vieira A; et al. "Advancing tools to promote health equity across European Union regions: the EURO-HEALTHY project.". Health research policy and systems (2020): http://europepmc.org/abstract/med/32054540.
    10.1186/s12961-020-0526-y
  12. Bédard A; Antó JM; Fonseca JA; Arnavielhe S; Bachert C; Bedbrook A; Bindslev-Jensen C; et al. "Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App.". Allergy (2020): http://europepmc.org/abstract/med/31995656.
    10.1111/all.14204
  13. Marcus Oliveira; Gabriela Arrifano; Amanda Lopes-Araújo; Leticia Santos-Sacramento; Priscila Y. Takeda; Anthony DC; João O. Malva; Maria Elena Crespo-Lopez. "What Do Microglia Really Do in Healthy Adult Brain?". Cells (2019): https://www.mdpi.com/2073-4409/8/10/1293.
    10.3390/cells8101293
  14. Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al. "Development of a Healthy Lifestyle Assessment Toolkit for the General Public.". Frontiers in medicine (2019): http://europepmc.org/abstract/med/31316985.
    10.3389/fmed.2019.00134
  15. Bédard A; Basagaña X; Anto JM; Garcia-Aymerich J; Devillier P; Arnavielhe S; Bedbrook A; et al. "Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.". The Journal of allergy and clinical immunology (2019): http://europepmc.org/abstract/med/30951790.
    10.1016/j.jaci.2019.01.053
  16. Bousquet J; Bedbrook A; Czarlewski W; Onorato GL; Arnavielhe S; Laune D; Mathieu-Dupas E; et al. "Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.". Clinical and translational allergy (2019): http://europepmc.org/abstract/med/30911372.
    10.1186/s13601-019-0252-0
  17. Menditto E; Costa E; Midão L; Bosnic-Anticevich S; Novellino E; Bialek S; Briedis V; et al. "Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.". Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019): http://europepmc.org/abstract/med/30597673.
    10.1111/cea.13333
  18. Augusto-Oliveira M; Arrifano GPF; Malva JO; Crespo-Lopez ME. "Adult Hippocampal Neurogenesis in Different Taxonomic Groups: Possible Functional Similarities and Striking Controversies.". Cells (2019): http://europepmc.org/abstract/med/30764477.
    10.3390/cells8020125
  19. Bousquet J; Illario M; Farrell J; Batey N; Carriazo AM; Malva J; Hajjam J; et al. "The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.". Translational medicine @ UniSa (2019): http://europepmc.org/abstract/med/31360670.
  20. Bosnic-Anticevich, Sinthia; Costa, Elisio; Menditto, Enrica; Lourenço, Olga; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; et al. "ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy". (2019): http://hdl.handle.net/10400.6/9359.
    10.1111/all.13701
  21. Bousquet, J Jean; Schünemann, Holger J; Togias, Alkis; Erhola, Marina; Hellings, Peter W; Zuberbier, Torsten; Agache, Ioana; et al. "Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases". (2019): http://hdl.handle.net/10400.6/9365.
    10.1186/s13601-019-0279-2
  22. Bousquet, Jean; Pham-Thi, Nhân; Bedbrook, Anna; Agache, Ioana; Annesi-Maesano, Isabella; Ansotegui, Ignacio; Anto, Josep M; et al. "Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1)". (2019): http://hdl.handle.net/10400.6/9366.
    10.21037/jtd.2019.08.64
  23. Bousquet J; Arnavielhe S; Bedbrook A; Bewick M; Laune D; Mathieu-Dupas E; Murray R; et al. "MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.". Clinical and translational allergy (2018): http://europepmc.org/abstract/med/30386555.
    10.1186/s13601-018-0227-6
  24. Oriá RB; Malva JO; Foley PL; Freitas RS; Bolick DT; Guerrant RL. "Revisiting Inbred Mouse Models to Study the Developing Brain: The Potential Role of Intestinal Microbiota.". Frontiers in Human Neuroscience (2018): http://europepmc.org/abstract/med/30283311.
    10.3389/fnhum.2018.00358
  25. Bousquet J; Hellings PW; Agache I; Amat F; Annesi-Maesano I; Ansotegui IJ; Anto JM; et al. "Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.". The Journal of allergy and clinical immunology (2018): http://europepmc.org/abstract/med/30273709.
    10.1016/j.jaci.2018.08.049
  26. Samreth D; Arnavielhe S; Ingenrieth F; Bedbrook A; Onorato GL; Murray R; Almeida R; et al. "Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study.". The World Allergy Organization Journal (2018): http://europepmc.org/abstract/med/30061979.
    10.1186/s40413-018-0194-3
  27. Malva JO; Amado A; Rodrigues A; Mota-Pinto A; Cardoso AF; Teixeira AM; Todo-Bom A; et al. "The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study.". Frontiers in medicine (2018): http://europepmc.org/abstract/med/29868588.
    10.3389/fmed.2018.00132
  28. McIntosh J; Alonso A; MacLure K; Stewart D; Kempen T; Mair A; Castel-Branco M; et al. "A case study of polypharmacy management in nine European countries: Implications for change management and implementation.". PloS one (2018): http://europepmc.org/abstract/med/29668763.
    10.1371/journal.pone.0195232
  29. Bousquet J; Agache I; Aliberti MR; Angles R; Annesi-Maesano I; Anto JM; Arnavielhe S; et al. "Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).". Allergy (2018): http://europepmc.org/abstract/med/28600902.
    10.1111/all.13218
  30. de Aquino CC; Leitão RA; Oliveira Alves LA; Coelho-Santos V; Guerrant RL; Ribeiro CF; Malva JO; Silva AP; Oriá RB. "Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress.". Frontiers in nutrition (2018): http://europepmc.org/abstract/med/30687711.
    10.3389/fnut.2018.00131
  31. Amorim RP; Araújo MGL; Valero J; Lopes-Cendes I; Pascoal VDB; Malva JO; da Silva Fernandes MJ. "Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy.". Purinergic Signalling (2017): http://europepmc.org/abstract/med/28707031.
    10.1007/s11302-017-9573-4
  32. Caimmi D; Baiz N; Tanno LK; Demoly P; Arnavielhe S; Murray R; Bedbrook A; et al. "Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control.". Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017): http://europepmc.org/abstract/med/28886234.
    10.1111/cea.13025
  33. Hellings PW; Fokkens WJ; Bachert C; Akdis CA; Bieber T; Agache I; Bernal-Sprekelsen M; et al. "Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement.". Allergy (2017): http://europepmc.org/abstract/med/28306159.
    10.1111/all.13162
  34. Bousquet J; Onorato GL; Bachert C; Barbolini M; Bedbrook A; Bjermer L; de Sousa JC; et al. "CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report.". Clinical and translational allergy (2017): http://europepmc.org/abstract/med/29075437.
    10.1186/s13601-017-0173-8
  35. Stewart D; Gibson-Smith K; MacLure K; Mair A; Alonso A; Codina C; Cittadini A; et al. "A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people.". PloS one (2017): http://europepmc.org/abstract/med/29155870.
    10.1371/journal.pone.0188348
  36. Valero J; Bernardino L; Cardoso FL; Silva AP; Fontes-Ribeiro C; Ambrósio AF; Malva JO. "Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease.". Journal of Alzheimer's disease : JAD (2017): http://europepmc.org/abstract/med/28671124.
    10.3233/jad-170239
  37. Bousquet J; Bewick M; Cano A; Eklund P; Fico G; Goswami N; Guldemond NA; et al. "Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.". (2017): http://europepmc.org/abstract/med/27999855.
    10.1007/s12603-016-0803-1
  38. Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al. "Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).". (2017): http://europepmc.org/abstract/med/28239450.
    10.1186/s13601-016-0135-6
  39. Zussy C; Loustalot F; Junyent F; Gardoni F; Bories C; Valero J; Desarménien MG; et al. "Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.". (2016): http://europepmc.org/abstract/med/27629708.
    10.1523/jneurosci.0132-16.2016
  40. Bousquet J; Dinh-Xuan AT; Similowski T; Malva J; Ankri J; Barbagallo M; Fabbri L; et al. "Should we use gait speed in COPD, FEV1 in frailty and dyspnoea in both?". (2016): http://europepmc.org/abstract/med/27478189.
    10.1183/13993003.00633-2016
  41. Malva JO; Bousquet J. "Operational definition of active and healthy ageing: Roadmap from concept to change of management.". (2016): http://europepmc.org/abstract/med/26704254.
    10.1016/j.maturitas.2015.11.004
  42. Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al. "Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).". (2016): http://europepmc.org/abstract/med/27478588.
    10.1186/s13601-016-0116-9
  43. Bousquet J; Hellings PW; Agache I; Bedbrook A; Bachert C; Bergmann KC; Bewick M; et al. "ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.". (2016): http://europepmc.org/abstract/med/28050247.
    10.1186/s13601-016-0137-4
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  117. Ambrósio, A.F.; Silva, A.P.; Araújo, I.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M.. "Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024". European Journal of Pharmacology 406 2 (2000): 191-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034644868&partnerID=MN8TOARS.
    10.1016/S0014-2999(00)00659-2
  118. A. Cunha, R.; Malva, J.O.; Ribeiro, J.A.. "Pertussis toxin prevents presynaptic inhibition by kainate receptors of rat hippocampal [3H]GABA release". FEBS Letters 469 2-3 (2000): 159-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034629239&partnerID=MN8TOARS.
    10.1016/S0014-5793(00)01272-2
  119. Cunha, R.A.; Malva, J.O.; Ribeiro, J.A.. "Kainate receptors coupled to G(i)/G(o) proteins in the rat hippocampus". Molecular Pharmacology 56 2 (1999): 429-433. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032793961&partnerID=MN8TOARS.
  120. Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-Da-Silva, P.; Carvalho, A.P.; Carvalho, C.M.. "Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists". Neuropharmacology 38 9 (1999): 1349-1359. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244425608&partnerID=MN8TOARS.
    10.1016/S0028-3908(99)00058-1
  121. Malva, João O.; Ambrósio, António F.; Carvalho, Arsélio P.; Carvalho, Caetana M.. "Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels". (1998): http://hdl.handle.net/10316/5472.
  122. Malva, João O.; Carvalho, Arsélio P.; Carvalho, Caetana M.. "Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release". (1998): http://hdl.handle.net/10316/5471.
  123. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Commentary: Kainate receptors in hippocampal CA3 subregion: Evidence for a role in regulating neurotransmitter release". Neurochemistry International 32 1 (1998): 1-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031606083&partnerID=MN8TOARS.
    10.1016/S0197-0186(97)00046-6
  124. Malva, J.O.; Ambrsio, A.F.; Carvalho, A.P.; Carvalho, C.M.. "Commentary: Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: Characterization of the activated voltage sensitive Ca2+ channels". Neurochemistry International 32 1 (1998): 7-16. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031594364&partnerID=MN8TOARS.
    10.1016/S0197-0186(97)00048-X
  125. Sequeira, S.M.; Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide". Nitric Oxide - Biology and Chemistry 1 4 (1997): 315-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345451156&partnerID=MN8TOARS.
    10.1006/niox.1997.0144
  126. Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Inhibition of N-, P/Q- and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor". European Journal of Pharmacology 340 2-3 (1997): 301-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344813710&partnerID=MN8TOARS.
    10.1016/S0014-2999(97)01451-9
  127. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Domoic acid induces the release of glutamate in the rat hippocampal CA3 sub-region". NeuroReport 7 7 (1996): 1330-1334. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029679826&partnerID=MN8TOARS.
  128. Malva, J.; Carvalho, A.; Çarvalho, C.. "Identification of a presynaptic kainate receptor which modules the exocytotic release of glutamate in rat hippocampal CA3 synaptosomes". FASEB Journal 10 3 (1996): http://www.scopus.com/inward/record.url?eid=2-s2.0-33748975701&partnerID=MN8TOARS.
  129. Carvalho, C.; Ambrócio, A.; Malva, J.; Carvlho, A.. "Modulation oh intracellular ca2+ and exocytotic glulamate release by adhnosinh a1 rhchptor activation in the hippocampus". FASEB Journal 10 3 (1996): http://www.scopus.com/inward/record.url?eid=2-s2.0-25744431605&partnerID=MN8TOARS.
  130. Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of Ca2+ channels by activation of adenosine A1 receptors in rat striatal glutamatergic nerve terminals". Neuroscience Letters 220 3 (1996): 163-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030595814&partnerID=MN8TOARS.
    10.1016/S0304-3940(96)13252-3
  131. Carvalho, C.M.; Ferreira, I.L.; Duarte, C.B.; Malva, J.O.; Tretter, L.; Adam-Vizi, V.; Carvalho, A.P.. "Relation of [Ca2+]i to dopamine release in striatal synaptosomes: role of Ca2+ channels". Brain Research 669 2 (1995): 234-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028839020&partnerID=MN8TOARS.
  132. Malva, J.O.; Ambrósio, A.F.; Cunha, R.A.; Ribeiro, J.A.; Carvalho, A.P.; Carvalho, C.M.. "A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion". Neuroscience Letters 185 2 (1995): 83-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028912732&partnerID=MN8TOARS.
  133. Carvalho, C.M.; Malva, J.O.; Duarte, C.B.; Carvalho, A.P.. "Characterization of voltage-sensitive Ca2+ channels activated by presynaptic glutamate receptor stimulation in hippocampus". Annals of the New York Academy of Sciences 757 (1995): 457-459. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029129986&partnerID=MN8TOARS.
    10.1111/j.1749-6632.1995.tb17505.x
  134. Malva, J.O.; Carvalho, A.P.; Carvalho, C.M.. "Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus". British Journal of Pharmacology 113 4 (1994): 1439-1447. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027968075&partnerID=MN8TOARS.
  135. Malva, J.O.; Lopes, M.C.F.; Vale, M.G.P.; Carvalho, A.P.. "Action of antiestrogens on the (Ca2+ + Mg2+)-ATPase and Na+/Ca2+ exchange of brain cortex membranes". Biochemical Pharmacology 40 8 (1990): 1877-1884. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025196039&partnerID=MN8TOARS.
Magazine article
  1. Malva J. "Necrotic-like BV-2 microglial cell death due to methylmercury exposure", Front Pharmacol . , 2022
    10.3389/fphar.2022.1003663
Report
  1. Pardal, António; Peixoto, E.; Quatorze, Marta; Azul, AM; Ramalho-Santos, José; João O. Malva; Santana, Paula; Almendra, Ricardo; Loureiro, Adriana. 2019. DEL09 - Final 2019 Activity report. HeaLIQs4Cities Technical Report.
Thesis / Dissertation
  1. Barbosa, Joana Santos. "In vivo single cell analysis reveals distinct behavior of neural stem and progenitor cells in homeostasis and regeneration in the adult brain". PhD, 2015. http://hdl.handle.net/10316/26444.
  2. Grade, Sofia Cristina de Morais. "Strategies for the use of neural stem cells in brain repair". PhD, 2012. http://hdl.handle.net/10316/21224.
  3. Neiva, Ismael. "Modulatory effects of the chemokine Fractalkine in a model of endotoxin-induced microglial activation". Master, 2012. http://hdl.handle.net/10316/25150.
  4. Rosa, Alexandra Isabel Freitas. "Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis : focus on the soluble factor angiopoietin-1 and direct contact via lamimim-1/a6ß1 integrin and connexin 43 as new targets for brain repair". PhD, 2011. http://hdl.handle.net/10316/17778.
  5. Ferreira, Raquel Margarida da Silva. "Contribution of microglia to neural inflammation : neuropeptide y modulates interleukin-1ß-induced microglia activation". PhD, 2010. http://hdl.handle.net/10316/18175.
  6. Domingues, Helena Sofia de Azevedo. "Role of TH1 and TH17 CD4+ T cell subsets in the pathogenesis of experimental autoimmune encephalomyelitis". PhD, 2010. http://hdl.handle.net/10316/13895.
  7. Silva, Bruno Alexandre Cordeiro. "Potencial neuroprotector de extractos e compostos isolados de Hypericum perforatum". PhD, 2008. http://hdl.handle.net/1822/7605.
  8. Pinheiro, Paulo César da Silva. "Presynaptic kainate receptors in the hippocampus : a critical role for GluR7 at the mossy fiber synapse". PhD, 2006. http://hdl.handle.net/10316/10149.
  9. Silva, Ana Paula Pereira da. "Neurotoxicidade e neuroprotecção no hipocampo : papel dos receptores do neuropeptídeo Y". PhD, 2003. http://hdl.handle.net/10316/10158.
  10. Malva, João José Oliveira. "Acção moduladora do glutamato nos terminais nervosos do hipocampo de rato : identificação de um receptor de cainato na sub-região CA3". PhD, 1997. http://hdl.handle.net/10316/10186.

Intellectual property

Patent
  1. Xapelli S; Reis R; Malva JO. 2013. "Oligodendrocyte differentiation". Portugal.
    Expired
  2. Malva JO; Schitine C; Agasse F; Xapelli S; Silva AP; Reis R. 2010. "Process for treating neural stem cells based on ampakines and/or other modulators of ionotropic glutamate receptors, compositions thereof and their use in CNS conditions". Portugal.
    Expired
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2012 - 2015 In vivo single cell analysis reveals distinct behavior of neural stem and progenitor cells in homeostasis and regeneration in the adult brain
Co-supervisor of Joana Santos Barbosa
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2014 Migration and differentiation of neuronal precursors in the postnatal brain: insights from the subventricular zone and cerebellum
Supervisor of Maria Francisca Santos Eiriz
Universidade Nova de Lisboa, Portugal
2010 - 2013 Methamphetamine-induced hippocampal dysfunction: the role of pro-inflammatory cytokines and neuropeptide Y
Co-supervisor of Joana Teresa Ferreira Gonçalves
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013 Strategies for the use of neural stem cells in brain repair
Supervisor of Sofia Cristina Soares de Morais Grade
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2011 Role of intercelular communication between endotelial and stem cells in stemness and neurogenesis
Co-supervisor of Alexandra Isabel Freitas Rosa
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011 Neuropeptide Y modulates interleukin-1beta-induced microglia activation
Supervisor of Raquel Margarida da Silva Ferreira
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2010 Role of TH1 and TH17 CD4+ T cells subsets in the pathogenesis of experimental autoimmune encephalomyelitis
Co-supervisor of Helena Sofia de Azevedo Domingues
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2008 Inflammation in excitotoxic neuronal death and survival: onvolvement of tumor necrosis factor-alpha and interleukin-1beta
Supervisor of Liliana Inácio Bernardino
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2008 Neuroprotective and antiepileptic role of neuropeptide Y
Supervisor of Sara Alves Xapelli
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2003 - 2007 Neuroprotective potential of extracts and compounds isolated from Hypericum perforatum
Co-supervisor of Bruno Alexandre Cordeiro Silva
Universidade do Minho Escola de Ciências, Portugal
2002 - 2006 Presynaptic kainate receptors in the hippocampus: a critical role for GluR7 at the mossy fiber synapse
Supervisor of Paulo César da Silva Pinheiro
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2000 - 2003 Neurotoxicity and neuroprotection in the hippocampus: role of neuropeptide Y receptors
Co-supervisor of Ana Paula Pereira da Silva
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2019 Christiane Costa Aquino
(Thesis) Arguer
 Christiane Costa Aquino (PhD)
Universidade Federal do Ceará, Brazil
2018 António José Braga Gomes Osório Gomes Salgado
(Thesis) Arguer
 António José Braga Gomes Osório Gomes Salgado (Aggregation)
Universidade do Minho Escola de Medicina, Portugal
2018 Raúl de Sousa Freitas
(Thesis) Arguer
 Raúl de Sousa Freitas (PhD)
2017 Andreia de Faria Martins Rosa
President of the jury
 Andreia de Faria Martins Rosa (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 Ana Sofia Simões Bento Baptista
Thesis Member
 Ana Sofia Simões Bento Baptista (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 Rita Isabel Pedro Aroeira
(Thesis) Arguer
 Rita Isabel Pedro Aroeira (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 Casper Gotzche
(Thesis) Arguer
 Casper Gotzche (PhD)
Københavns Universitet Afdeling for Almen Medicin, Denmark
2014 Filipa Solange Parreira Lourenço Cardoso
(Thesis) Arguer
 Filipa Solange Parreira Lourenço Cardoso (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 António Pinto-Duarte
(Thesis) Arguer
 António Pinto-Duarte (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2013 Clara Maria Pires Costa de Bastos Monteiro
(Thesis) Arguer
 Clara Maria Pires Costa de Bastos Monteiro (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Helder Rui Cardoso da Cruz
(Thesis) Arguer
 Helder Rui Cardoso da Cruz (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Catarina Sofia Oliveira Miranda
(Thesis) Arguer
 Catarina Sofia Oliveira Miranda (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 Armando Cardoso
(Thesis) Arguer
 Armando Cardoso (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2010 Joana Catarina Cravo Lourenço
Thesis Member
 Joana Catarina Cravo Lourenço (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 Márcia Maria de Almeida Aranha
(Thesis) Arguer
 Márcia Maria de Almeida Aranha (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010 Hamad Ali
(Thesis) Arguer
 Hamad Ali (PhD)
Newcastle University, United Kingdom
2009 Paula Margarida Gomes Canas
Thesis Member
 Paula Margarida Gomes Canas (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 Robert Nunan
(Thesis) Arguer
 Robert Nunan (PhD)
Solent University, United Kingdom
2009 Michael Decressac
(Thesis) Arguer
 Michael Decressac (PhD)
Université de Poitiers, France
2008 Marta Sofia Carvalho Teixeira Pinto
(Thesis) Arguer
 Marta Sofia Carvalho Teixeira Pinto (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2007 Ana Filipa Duarte Nunes
(Thesis) Arguer
 Ana Filipa Duarte Nunes (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 Diana Lina Jerónimo da Cunha Reis
(Thesis) Arguer
 Diana Lina Jerónimo da Cunha Reis (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2006 Adelaide Maria Afonso Fernandes
(Thesis) Arguer
 Adelaide Maria Afonso Fernandes (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2005 Henrique Manuel Paixão dos Santos Girão
Thesis Member
 Henrique Manuel Paixão dos Santos Girão (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2000 António Francisco Rosa Gomes Ambrósio
Thesis Member
 António Francisco Rosa Gomes Ambrósio (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Association member

Society Organization name Role
2013/01/17 - Current Ageing@Coimbra Coordenador
2016 - 2019 Reference Site Collaborative Network Treasurer and member of the Executive Committee
2015/03 - 2015/12 InnoStars, EIT Health Deputy Director
2007/05 - 2011/05 Sociedade Portuguesa de Neurociências (SPN) Presidente de Direção

Consulting

Activity description Institution / Organization
2022/01/01 - Current Consultor da Fundação La Caixa, em Portugal, para a área do Envelhecimento Obra Social La Caixa, Spain

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020 - Current Millenium Science Initiative
Evaluator
 Millenium Science Initiative, Chile
2020 - Current National Science Center
Evaluator
 National Science Center, Poland National Science Center
2017 - Current Bolsas D. Manuel de Mello
Evaluator
 José de Mello Saúde
2015 - Current Dutch Diabetes Foundation
Evaluator
 Dutch Diabetes Foundation
2015 - Current Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Evaluator
 Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil Conselho Nacional de Desenvolvimento Científico e Tecnológico
2014 - Current Multisclerosis Research Australia
Evaluator
 Multisclerosis Research Australia, Australia Multisclerosis Research Australia
2012 - Current La Comisión Nacional de Investigación Científica y Tecnológica
Evaluator
 La Comisión Nacional de Investigación Científica y Tecnológica (CONICYT), Chile La Comisión Nacional de Investigación Científica y Tecnológica (CONICYT)
2007 - Current Agency for Science, Technology and Research (A*STAR)
Evaluator
 Agency for Science, Technology and Research (A*STAR) , Singapore Agency for Science, Technology and Research (A*STAR)
2021/01/01 - 2021/01/31 Roteiro Nacional de Infraestruturas _ FCT Aviso 04/SAICT/2020 (PO Norte) Universidade de Coimbra, Portugal
2016/09 - 2016/12 Presidente de Comissão de Avaliação de Unidade de Investigação Científica, HARC, Lodz, Polónia
Evaluator
 Comissão Europeia, Belgium
2016/09 - 2016/12 Comissão de Avaliação de Unidade de Investigação, ITRIBiS, Sevilha, Espanha; REGPOT
Evaluator
 Comissão Europeia, Belgium
2013 - 2015 FISM, Italian Multiple Sclerosis Foundation
Evaluator
 Associazione Italiana Sclerosi Multipla, Italy Associazione Italiana Sclerosi Multipla
2014/06 - 2014/09 ERA-Net Neuron
Evaluator
 Comissão Europeia, Belgium
2012 - 2013 Alzheimer’s Association
Evaluator
 Alzheimer's Association, United States Alzheimer's Association
2006 - 2009 Health Research Board
Evaluator
 Health Research Board, Ireland Health Research Board
Distinctions

Other distinction

2019 Ageing@Coimbra, Reference Site 4 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Belgium
2016 Ageing@Coimbra, Reference Site 3 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Belgium
2013 Ageing@Coimbra, Reference Site 2 estrelas
European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Belgium