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I hold a degree in Chemical engineer from NOVA School of Science and Technology, Portugal (2003), and I pursued my Ph.D. in Technological Chemistry with Dr João Paulo Leal at the University of Lisbon, Portugal (2012). Part of my PhD was undertaken between the Isotope Institute in Hungary (2008) and the University of California, Irvine, USA in 2011. In 2013, I joined ITQB NOVA, Portugal, where I was a postdoctoral fellow under Claudio Soares Lab. Between 2014 and 2018, I worked as post-doctoral researcher at IST and, since 2018, I was appointed Researcher. From an academic standpoint, since 2021 I have been a visiting assistant professor on the master's programme in Computational Biology at the University of Coimbra, and in 2022 I was a visiting professor at the School of Health Technology, IPL in Lisbon. I was awarded a 1 FCT-funded project as Principal Investigator (PTDC/QUI-OUT/32243/2017) and 1 FCT-funded under National Network for Advanced Computing (2022.15874.CPCA.A2) as co-PI. The PTDC/QUI-OUT/32243/2017 project is focused on the study of protein-protein interactions as G protein-coupled receptors, addressing their importance as targets/biomarkers for novel drug design. Following a multidisciplinary approach, I enriched my expertise upon exploring the interface between computational tools and experimental work (in vitro and in vivo studies). Within this topic, in 2021 I was part of the winning team of the "Pick yoUR bRain" - Born from Knowledge 2021 award from the Innovation Agency. Also, I am involved in the retargeting of virus-like particles aiming at the specific delivery of drugs and/or imaging agents to cancer cells. While working on these two main research topics, I have fostered several other research collaborations as Irina S. Moreira (CIBB/UC), Z.H. Gümüs (Icahn School of Medicine, USA), A. Schiedel (Bonn University) and A. Bonvin (Utrecht University) where theoretical studies gain relevance for a better understanding of the experimental results. In summary, I have published 40 articles in journals and (co)author of 9 book chapters. I am actively involved in mentoring young researchers: 3 ongoing PhD students, 14 MSc (2 ongoing), and 7 undergraduate students (4 of them abroad). I have organized 3 workshops/conferences. My project management skills are evident in my involvement in several projects. In fact, 8 projects funded by FCT (1 as PI and 1 as co-PI), 4 international projects of the International Atomic Energy Agency (IAEA) and 2 COST actions. Owing to my skills in computational biophysics, I am team member of the High-Performance Computing task force at IST. I was recently invited to be Guest Editor of a Special Issue on " Retargeting of Virus-Like Particles “at “Frontiers in Cellular and Infection Microbiology” (IF 5.882, Q1).
Identification

Personal identification

Full name
Rita Lourenço Paiva de Melo

Citation names

  • Melo, Rita
  • Melo, Rita P.

Author identifiers

Ciência ID
ED1A-5FE8-8E69
ORCID iD
0000-0003-1056-1007
Google Scholar ID
https://scholar.google.pt/citations?user=wzrT-8gAAAAJ&hl=pt-PT
Researcher Id
http://www.webofscience.com/wos/author/record/K-1650-2013
Scopus Author Id
22938248300

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Advanced (C1) Proficiency (C2) Advanced (C1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Upper intermediate (B2) Proficiency (C2) Intermediate (B1)
Education
Degree Classification
2008/12/12
Concluded
Química (Doutoramento)
Major in Especialidade: Química Tecnológica
Universidade de Lisboa, Portugal
"Application of Ionizing Radiation to Persistent Organic Pollutants Decomposition" (THESIS/DISSERTATION)
Louvor e Distinção
2005/02/28
Concluded
Mestrado em Gestão e Consevação da Natureza (Mestrado)
Universidade dos Açores - Campus de Angra do Heroísmo, Portugal
"Estudo da Radiação Ionizante no Tratamento de Águas Residuais: "Aspectos Tecnológicos e Sócio-Económicos"" (THESIS/DISSERTATION)
muito bom
2002/08/02
Concluded
Engenharia Química (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
14
Affiliation

Science

Category
Host institution
Employer
2018/11/15 - Current Contracted Researcher (Research) Centro de Ciências e Tecnologias Nucleares, Portugal
Associação para o Desenvolvimento do Instituto Superior Técnico, Portugal
2014/10 - 2018/11 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Centro de Ciências e Tecnologias Nucleares, Portugal
2013/11 - 2014/09 Postdoc (Research) Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
Centro de Ciências e Tecnologias Nucleares, Portugal
2013/04 - 2013/10 Postdoc (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2001 - 2002 Research Trainee (Research) NATO, Belgium
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2022/10/15 - Current Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2022/02/14 - Current Visiting Professor (University Teacher) Universidade de Coimbra, Portugal
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2011 - 2013 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Setúbal, Portugal
Instituto Politécnico de Setúbal, Portugal

Others

Category
Host institution
Employer
2014/09/01 - Current Colaboradora externa CNC.IBILI, Portugal
Universidade de Coimbra, Portugal
2011/07 - 2011/12 IAEA fellowship POR/11002 International Atomic Energy Agency, Austria
University of California at Irvine Department of Chemical Engineering and Material Sciences, United States
2008/04 - 2008/12 IAEA fellowship POR/07005 International Atomic Energy Agency, Austria
Izotóp Intézet Kft, Hungary
2005/07 - 2005/12 IAEA fellowship POR/05003 International Atomic Energy Agency, Austria
Instituto de Pesquisas Energeticas e Nucleares, Brazil
Projects

Grant

Designation Funders
2014/09/04 - 2018/10/31 Target-specific delivery of radioactivity to cancer cells by virus-like particles: a computational chemistry and bioengineering approach
SFRH/BPD/97650/2013
Post-doc
Centro de Ciências e Tecnologias Nucleares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/10 - 2014/08 Application of Ionizing Radiation for a Sustainable Environment
RECI/AAG-TEC/0400/2012
Post-doc
Centro de Ciências e Tecnologias Nucleares, Portugal
Universidade de Lisboa Instituto Superior Técnico
2013/04 - 2013/09 Proton transfer and proton pumping in haem-copper oxidases. Methodological developments and their application to unravel the molecular mechanism
PTDC/QUIBIQ/113446/2009
Post-doc
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/05/08 - 2012/12/12 Application of ionising radiation on the degradation of persistent organic compounds
SFRH / BD / 41996 / 2007
PhD Student Fellow
Centro de Ciências e Tecnologias Nucleares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/05/01 - 2012/08/31 APLICAÇÃO DA RADIAÇÃO IONIZANTE À DECOMPOSIÇÃO DE POLUENTES ORGÂNICOS PERSISTENTES
SFRH/BD/41996/2007
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/07 - 2011/10 Radiation Processing Facilities and Applications
IAEA POR11002
Invited Scientist Fellow
University of California at Irvine Department of Chemical Engineering and Material Sciences, United States
International Atomic Energy Agency
Concluded
2008/04 - 2008/07 Implementation of wastewater treatment using radiation
IAEA POR07005
Invited Scientist Fellow
Izotóp Intézet Kft, Hungary
International Atomic Energy Agency
Concluded
2005/08 - 2005/12 Radiation Processing – Detoxification of wastewater using electron beam and gamma source
IAEA POR05003
Invited Scientist Fellow
Instituto de Pesquisas Energeticas e Nucleares, Brazil
International Atomic Energy Agency
Concluded
2003 - 2005 Impact of Electron beam and Gamma Radiation on wastewater treatment: comparative studies
IAEA 302-F2-POR-12017
Research Fellow
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
International Atomic Energy Agency
Concluded

Contract

Designation Funders
2023/06/01 - Current The influence of a known mutation into the stargazin/Kv7.2 dynamics and function
2022.15874.CPCA.A2
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia, Portugal
Ongoing
2019/09/16 - Current Targeting the transporters of cationic amino acids for cancer radiotheranostics: experimental and computacional chemistry approach
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/09/01 - Current Alvejamento de transportadores de aminoácidos catiónicos para radioteranóstica do cancro: uma abordagem experimental e de química computacional
PTDC/QUI-NUC/30147/2017
Researcher
Associação para o Desenvolvimento do Instituto Superior Técnico, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06 - Current Development of a novel class of antibody-drug conjugates molecules for cancer treatment
PTDC/BTM-SAL/32085/2017
Researcher
Centro de Ciências e Tecnologias Nucleares, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06 - Current COST ACTION CA 18133 ERNEST-European Research Network on Signal Transduction
CA18133
Researcher
European Cooperation in Science and Technology, Belgium
Ongoing
2022/01/01 - 2024/12/31 A molecular and nano approach to target the RANK-TRAF6 interface for bone metastases treatment
PTDC/QUI-OUT/3854/2021
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Centro de Ciências e Tecnologias Nucleares, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/11/15 - 2024/11/14 Not Available
DL 57/2016/CP1384/CT0086
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/02/01 - 2024/01/31 Cutting-Edge Virus-Host Interactome Discovery: A Multi-Omics AI Driven Approach
DSAIPA/DS/0118/2020
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/09/04 - 2022/06/04 Membrane proteins - development of new computational approaches and its application to G-Protein Coupled Receptors
PTDC/QUI-OUT/32243/2017
Principal investigator
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Centre for Nuclear Sciences and Technologies
UID/Multi/04349/2019
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Centro de Ciências e Tecnologias Nucleares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2017 Electrical discharges with liquids for future applications
COST TD1208
Researcher
Instituto Superior Técnico Departamento de Física, Portugal
European Cooperation in Science and Technology
Concluded
2014/04/01 - 2015/07/31 Padrões de inactivação de vírus entéricos por radiação ionizante
EXPL/DTP-SAP/2338/2013
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Kinetic study of biorecalcitrant compounds degradation by pulse radiolysis
PTDC/QUI-QUI/104229/2008
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2013 Kinetic study of biorecalcitrant compounds degradation by pulse radiolysis
Technical development
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2001 - 2002 New approach to waste recovery into selective adsorbents of heavy metals
OTAN nº 977984
Research Fellow
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
NATO

Other

Designation Funders
2022/01/01 - Current A molecular and nano approach to target the RANK-TRAF6 interface for bone metastases treatment
PTDC/QUI-OUT/3854/2021
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Ongoing
2011 - 2016 Radiation treatment of wastewater for reuse with particular focus on wastewaters containing organic pollutants
IAEA-CRP no. 1539
Researcher
International Atomic Energy Agency, Austria
Concluded
Outputs

Publications

Book chapter
  1. Melo R.. "Arrestin and G Protein Interactions with GPCRs: A Structural Perspective". 109-179. Wiley, 2022.
    10.1002/9781119564782.ch5
  2. Preto, A.J.; Marques-Pereira, C; Baptista, Salete J.; Bueschbell, B.; Barreto, Carlos A.V.; Gaspar, A.T.; Pinheiro, I.; et al. "Targeting GPCRs Via Multi-Platforms Arrays and AI". In Reference Module in Biomedical Sciences. Elsevier, 2021.
    10.1016/b978-0-12-820472-6.00048-7
  3. Barreto, Carlos A.V.; Baptista, Salete J.; Preto, António José; Matos-Filipe, Pedro; Mourão, Joana; Melo, Rita; Moreira, Irina. "Prediction and targeting of GPCR oligomer interfaces". In Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, 105-149. Elsevier, 2020.
    Published • 10.1016/bs.pmbts.2019.11.007
  4. Lemos, Agostinho; Melo, Rita; Moreira, Irina S.; Cordeiro, M. Natália D. S.. "Computer-Aided Drug Design Approaches to Study Key Therapeutic Targets in Alzheimer’s Disease". In Computational Modeling of Drugs Against Alzheimer’s Disease, 61-106. Springer New York, 2017.
    Published • 10.1007/978-1-4939-7404-7_3
  5. Cabo Verde, Sandra; Guerreiro, D.; Silva, T.; Madureira, J.; Santos, P.; Melo, Rita; Margaça, F.. "Applications of radiation technologies for developing green processes for treatment of biological hazards". In Radiation Technology for Cleaner Products and Processes, 151-161. Austria, 2016.
    Published
  6. Cabo Verde, Sandra; Melo, Rita; Marcos, H; Nunes, I.; Dores, V.; Reis, J.; Teubig, Pamela; Santos, .P; Botelho, M.L.. "Radiation Technology: Processes and Products - Concepts and Applications, in Radiation Processing Technology Applications". In Radiation processing tecnology applications, 4-20. India, 2010.
    Published
  7. Cabo Verde, Sandra; Melo, Rita; Marcos, Helena; Nunes, Inês; Dores, Vânia; Antonio, Amilcar L.; Reis, Joana; et al. "Radiation Technology: Processes and Products - Concepts and Applications". In Radiation Processing Technology Applications. Dehli, India: Shriram Institute for Industrial Research, 2010.
    Published
  8. M.L.Botelho; Branco, J.; Freitas, C.; P. Ferreira ; A. Belchior; A. Costa; Í. De Sousa; et al. "Implementation of ionising radiation on wastewater treatment: The Portuguese study case". In Radiation Treatment of Polluted Water and Wastewater, 141-159. Austria, 2008.
    Published
  9. Lyubchik, S. B.; Melo, R.; Palma, C.; Fonseca, I. M.. "Adsorption Equilibrium in the System “Cr (III) — Activated Carbon”". In Role of Interfaces in Environmental Protection, 355-377. Springer Netherlands, 2003.
    Published • 10.1007/978-94-010-0183-0_22
Conference abstract
  1. Madureira, Joana; Pimenta, Andreia I; Melo, Rita; Cabo Verde, Sandra; Margaça, Fernanda M. A.. "Application of ionizing radiation to the cork wastewater treatment and valorization". Paper presented in 1st International Conference on Sustainable Water Processing, 2016.
  2. Madureira, Joana; Melo, Rita; Cabo Verde, Sandra; Matos, Inês; Bernardo, Maria; Noronha, João P.; Fonseca, Isabel M; Margaça, Fernanda. "Synthesized activated carbon for adsorption/desorption of antioxidant compounds". Paper presented in 10º Encontro Nacional de Catálise e Materiais Porosos, 2016.
  3. Madureira, Joana; Barros, Lillian; Melo, Rita; Santos, Pedro M.P.; Falcão, António N.; Cabo Verde, Sandra; Ferreira, Isabel C.F.R.; Margaça, Fernanda M.A.. "Degradation of compounds present in cork boiling water by gamma radiation". Paper presented in XVI Latin-American Congress on Chromatography & 9th National Meeting on Chromatography., Lisboa, 2016.
  4. Madureira, Joana; Pimenta, Andreia I.; Ribeiro, Joana; Popescu, Larisa; Besleaga, Alexandra; Melo, Rita; Santos, Pedro MP; et al. "Effects of gamma radiation on cork wastewater toxicity". Paper presented in 6th Congress of Microbiology and Biotechnology, 2015.
  5. Madureira, Joana; Melo, Rita; Ceriani, Elisa; Silva, Telma; Santos, Pedro MP; Marotta, Ester; Pinhão, Nuno; Margaça, F.M.A.; Paradisi, Cristina. "Oxidation of clofibric acid in water by electrical discharge and gamma radiation". Paper presented in 2nd Annual Meeting of COST Action "Electrical Discharges with Liquids for Future Applications", 2015.
  6. Guerreiro, Duarte; Silva, Telma; Meneses, Márcia; Madureira, Joana; Melo, Rita; Cabo Verde, Sandra; Margaça, F.M.A.. "Gamma Radiation Effects On Microbial Inactivation And Antioxidant Activity Of Cherry Tomatoes". Paper presented in International Symposium on Food Safety and Quality: Applications of Nuclear and Related Techniques - IAEA CN-222, 2014.
  7. Meneses, Márcia; Madureira, Joana; Melo, Rita; Antonio, Amilcar L.; Cabo Verde, Sandra. "Gamma irradiation effects on microbial inactivation and antioxidant activity of Melissa officinalis". Paper presented in ICEH 2014 ¿ 3rd International Congress on Environmental Health, 2014.
  8. Melo, Rita; Madureira, Joana; Neves, José; Pinhão, Nuno; Margaça, F.M.A.. "Degradation of hemoglobin on slaughterhouses wastewater using a DBD system". Paper presented in 1st Annual Meeting of COST Action "Electrical Discharges with Liquids for Future Applications", 2014.
Conference paper
  1. Moreira, Irina; Almeida, José; Preto, António; Melo, Rita; Gümüs, Zeynep; Costa, Joaquim; Bonvin, Alexandre. "Co-evolution importance on binding Hot-Spot prediction methods". 2017.
    Published • 10.3390/mol2net-02-03889
  2. Rita Melo; Jose Almeida; Sandra Cabo Verde; Zeynep Gumus; I. Moreira; J. Correia. "Structural mechanism of HER2-antibodies complexes by molecular dynamics studies". 2017.
    Published • 10.3390/mol2net-03-05084
  3. Melo, Rita; Maria Pinto; Carlos Vale; H. Burrows; William J. Cooper; G. Sontag. "Degradation of tetracyclines by gamma irradiation advanced oxidation processes (AOPs): Influence of the different radical species and the absorbed dose". Paper presented in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, São Francisco, 2014.
    Published
  4. Madureira, Joana; Melo, Rita; Cabo Verde, Sandra; Matos, Inês; Noronha, João P.; Fonseca, IM; Margaça, F.M.A.. "Desorption of phenolic compounds on activated carbons". Paper presented in 2nd International Congress on Water, Waste and Energy Management, 2014.
  5. Lima, Célia; Madureira, Joana; Melo, Rita; Cabo Verde, Sandra; Carolino, MM; Margaça, FMA. "A biodegradation bench study of cork wastewater using ioinizing radiation". Paper presented in 2nd International Conference WASTES: Solutions, Treatments and Opportunities, 2013.
  6. Madureira, Joana; Melo, Rita; Cabo Verde, Sandra; Lima, Célia; Matos, Inês; Noronha, João P.; Fonseca, IM; Margaça, F.M.A.. "Extraction of phenolic compounds from cork wastewater by adsorption onto activated carbon". Paper presented in 2nd International Conference WASTES: Solutions, Treatments and Opportunities, 2013.
  7. Botelho, M. Luísa; Cabo Verde, Sandra; Melo, Rita; Marcos, H; Silva, T; Nunes, I; Dores, V.; et al. "The implementation of radiation technology program in Portugal". Paper presented in NAARRI International Conference (NIC2010), Mumbai, 2010.
Conference poster
  1. Martins, Sofia A. ; 5C10-BAAC-7FD8; Marco Calvinho Cavaco; Melo, Rita; Vera Neves; Miguel Castanho; João Domingos Galamba Correia. "Bone-Seeking Peptides Targeting the RANK-TRAF6 Interface for Bone Metastases Theranostics". Paper presented in XVIII Iberian Peptide Meeting, 2023.
  2. Rosa, Cátia; Rúben Silva; Irina S. Moreira; João D. G. Correia; Melo, Rita. "Design of novel peptides to target the intracellular G protein-dopamine receptor type 2 (D2R) interface". Paper presented in Iberian Peptide Meeting 2023, 2023.
  3. Martins, Sofia A.; Cabo Verde, Sandra; Correia, João D. G.; Melo, Rita. "HIV-Based Virus-Like Particles: The Next Step in Targeted Therapy". Paper presented in 2nd Chem & Biochem Students Meeting, 2022.
  4. Pinho, Tiffany S.; Silva, Deolinda; Ribeiro, Jorge Cibrão; Marote, Ana; Lima Rui; Batista, Salete J; Melo, Rita; et al. "Dynamic Piezoelectric Stimulation Promotes Neuronal Differentiation". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Braga, Portugal, 2022.
  5. Gouveia, R. P.; Barreto, Carlos A.V.; Baptista, Salete J.; Preto, A.J.; Caldeira, Gladys Lima; Carvalho, Ana Luisa; Melo, Rita; Irina de Sousa Moreira. "The study of AMPAR: Stargazin interface through molecular dynamics". Paper presented in Encontro de Jovens Investigadores de Biologia Computacional Estrutural, 2021.
  6. Pinho, Tiffany; Silva, Deolinda; Ribeiro, Jorge Cibrão; Marote, Ana; Gomes, Eduardo D; Lima, Rui; Batista, Salete J; et al. "Neuronal Differentiation on Electroactive PVDF Films Dynamically Stimulated". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  7. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "NS1 dimer behavior through a Molecular Dynamics lens". Paper presented in Coimbra Chemistry Centre Day, 2021.
  8. Gouveia, Raquel; Barreto, Carlos A.V.; Baptista, Salete J.; Caldeira, Gladys Lima; Preto, A.J.; Melo, Rita; Carvalho, Ana Luisa; Moreira, Irina S. "The Structural and Functional Role of a CACNG2 Mutation in Psychiatric Disorders". Paper presented in Bioinformatics Open Days, 2021.
  9. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "A molecular Dynamics study of non-structural protein1 (NS1)". Paper presented in Advances in Computational Biology Conference ¿ Fostering Collaboration Among Women Scientists, 2019.
  10. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "Understanding the role of the non-structural protein I in the pathogenicity of influenza virus using a computational approach". Paper presented in Structural Bioinformatics Course, 2019.
  11. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "An integrative approach to understand protein plasticity ¿ The case of non-structural protein 1 from the influenza virus". Paper presented in PTNMR Satellite Meeting, 2019.
  12. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "A Molecular Dynamics Insight to Non-Structural Protein 1 (NS1) ¿ A Hub Protein Essential for Influenza Infection.". Paper presented in 4th Instruct Biennial Structural Biology Conference, 2019.
  13. Barreto, Carlos A.V.; Melo, Rita; Magalhães, Pedro R.; Renault, Pedro; Machuqueiro, Miguel; Moreira, Irina S.. "Understanding Structural and Dynamic Differences of GHSR-Gq nad GHSr-Arr Complexes". Paper presented in Encontro Jovens Investigadores de Biologia Estrutural e Computacional, 2018.
  14. Rosário-Ferreira, Nicia; Melo, Rita; Moreira, Irina S; Rui M M Brito. "Outline of a Molecular Dynamics Approach to Non- Structural Protein 1 (NS1) ¿ A Hub Protein essential for Influenza Infection". Paper presented in Encontro de Jovens Investigadores de Biologia Computacional Estrutural, 2018.
  15. Madureira, Joana; Pimenta, Andreia I.; Melo, Rita; Cabo Verde, Sandra; Margaça, F.M.A. "Application of ionizing radiation for treatment and valorization of cork wastewater". Paper presented in International Conference on Applications of Radiation Science and Technology - ICARST 2017, 2017.
  16. Pimenta, Andreia I.; Madureira, Joana; Ribeiro, J; Popescu, L.; Besleaga, A; Melo, Rita; Santos, P. M.P.; Falcão, A. N.; Margaça, F.M.A. "Evaluation of gamma radiation effects on cork wastewater toxicity.". Paper presented in 7th Congress of Microbiology and Biotechnology, Microbiotec 15, 2015.
  17. Madureira, Joana; Pimenta, Andreia I.; Dias, Maria Inês; Melo, Rita; Santos, Pedro M.P.; Falcão, António N.; Cabo Verde, Sandra; Ferreira, Isabel C.F.R.; Margaça, Fernanda M.A.. "Assessment of gamma radiation effects on antioxidant activity of cork wastewater". Paper presented in 2nd EUCheMS Congresso n Green and Sustainable Chemistry, 2015.
  18. Pimenta, Andreia I.; Madureira, Joana; Popescu, Larisa; Besleaga, Alexandra; Melo, Rita; Santos, P.M.P.; Falcão, A.; Cabo Verde, Sandra; Margaça, F.M.A. "Evaluation of the gamma radiation effects on cork wastewater toxicity". Paper presented in 2nd EuCheMS Congress on Green and sustainable, 2015.
Journal article
  1. Rafael Travassos; Sofia A. Martins; Ana Fernandes; João D. G. Correia; Rita Melo. "Tailored Viral-like Particles as Drivers of Medical Breakthroughs". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25126699.
    10.3390/ijms25126699
  2. Travassos, Rafael; Martins, Sofia A.; Fernandes, Ana; Correia, Joao D. G.; Melo, Rita. "Tailored Viral-like Particles as Drivers of Medical Breakthroughs". Preprints.org (2024): https://publons.com/wos-op/publon/66547698/.
    10.20944/PREPRINTS202404.0840.V1
  3. Beatriz Bueschbell; Pedro R. Magalhães; Carlos A.V. Barreto; Rita Melo; Anke C. Schiedel; Miguel Machuqueiro; Irina S. Moreira. "The World of GPCR dimers - mapping Dopamine Receptor D2 Homodimers in Different Activation States and Configuration Arrangements". Computational and Structural Biotechnology Journal (2023): https://doi.org/10.1016/j.csbj.2023.08.032.
    10.1016/j.csbj.2023.08.032
  4. Pinho, Tiffany S.; Silva, Deolinda; Ribeiro, Jorge Cibrao; Marote, Ana; Batista, Salete J.; Melo, Rita; Ribeiro, Clarisse; et al. "NEURONAL DIFFERENTIATION BY DYNAMIC PIEZOELECTRIC STIMULATION". Tissue Engineering Part A (2023): https://publons.com/wos-op/publon/62651930/.
  5. Martins, Sofia A.; Santos, Joana; Cabo Verde, Sandra Cabo; Correia, João D. G.; Melo, Rita. Corresponding author: Melo, Rita. "Construction of HER2-Specific HIV-1-Based VLPs". Bioengineering 9 11 (2022): 713. http://dx.doi.org/10.3390/bioengineering9110713.
    10.3390/bioengineering9110713
  6. Martins, Sofia A.; Santos, Joana; Silva, Rúben D. M.; Rosa, Cátia; Cabo Verde, Sandra; Correia, João D. G.; Melo, Rita. "How promising are HIV-1-based virus-like particles for medical applications". Frontiers in Cellular and Infection Microbiology 12 (2022): http://dx.doi.org/10.3389/fcimb.2022.997875.
    10.3389/fcimb.2022.997875
  7. Madureira, Joana; Melo, Rita; Margaça, Fernanda M.A.; Cabo Verde, Sandra. "Ionizing radiation for treatment of pharmaceutical compounds: A review". Journal of Water Process Engineering 49 (2022): 103179. http://dx.doi.org/10.1016/j.jwpe.2022.103179.
    Open access • 10.1016/j.jwpe.2022.103179
  8. Pinho, Tiffany S.; Silva, Deolinda; Ribeiro, Jorge Cibrão; Marote, Ana; Lima, Rui; Batista, Salete J.; Melo, Rita; et al. "Enhanced neuronal differentiation by dynamic piezoelectric stimulation". Journal of Biomedical Materials Research Part A (2022): http://dx.doi.org/10.1002/jbm.a.37443.
    Published • 10.1002/jbm.a.37443
  9. Rúben D. M. Silva; João Franco Machado; Kyle Gonçalves; Francisco M. Lucas; Salete Batista; Rita Melo; Tânia S. Morais; João D. G. Correia. "Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6". Molecules (2021): https://doi.org/10.3390/molecules26237349.
    10.3390/molecules26237349
  10. Nícia Rosário-Ferreira; Salete J. Baptista; Carlos A. V. Barreto; Filipe E. P. Rodrigues; Tomás F. D. Silva; Sara G. F. Ferreira; João N. M. Vitorino; et al. "In Silico End-to-End Protein–Ligand Interaction Characterization Pipeline: The Case of SARS-CoV-2". ACS Synthetic Biology (2021): https://doi.org/10.1021/acssynbio.1c00368.
    10.1021/acssynbio.1c00368
  11. Barreto, Carlos A. V.; Baptista, Salete J.; Preto, António J.; Silvério, Daniel; Melo, Rita; Moreira, Irina S.. "Decoding Partner Specificity of Opioid Receptor Family". Frontiers in Molecular Biosciences 8 (2021): http://dx.doi.org/10.3389/fmolb.2021.715215.
    10.3389/fmolb.2021.715215
  12. Joana Santos; Miguel Cardoso; Irina S. Moreira; João Gonçalves; João D. G. Correia; Sandra Cabo Verde; Rita Melo. "Integrated in Silico and Experimental Approach towards the Design of a Novel Recombinant Protein Containing an Anti-HER2 scFv". International Journal of Molecular Sciences 22 7 (2021): 3547-3547. https://doi.org/10.3390/ijms22073547.
    10.3390/ijms22073547
  13. D'Onofrio, Alice; Gano, Lurdes; Melo, Rita; Mendes, Filipa; Oliveira, Maria Cristina; Denoël, Thibaut; Schaefer, Niklaus; et al. "Biological evaluation of new TEM1 targeting recombinant antibodies for radioimmunotherapy: In vitro, in vivo and in silico studies". European Journal of Pharmaceutics and Biopharmaceutics 158 (2021): 233-244. http://dx.doi.org/10.1016/j.ejpb.2020.11.015.
    10.1016/j.ejpb.2020.11.015
  14. Preto, A. J.; Barreto, Carlos A. V.; Baptista, Salete J.; Almeida, José Guilherme de; Lemos, Agostinho; Melo, André; Cordeiro, M. Nátalia D. S.; et al. "Understanding the Binding Specificity of G-Protein Coupled Receptors toward G-Proteins and Arrestins: Application to the Dopamine Receptor Family". Journal of Chemical Information and Modeling 60 8 (2020): 3969-3984. http://dx.doi.org/10.1021/acs.jcim.0c00371.
    10.1021/acs.jcim.0c00371
  15. Melo, Rita; joana dos santos madureira; João Paulo Arriegas Estevão Correia Leal; Maria Luisa Botelho; William J. Cooper. "Aqueous degradation of esculetin (6,7-dihydroxycoumarin) using gamma radiation". Desalination and Water Treatment 181 (2020): 385-390. https://www.deswater.com/DWT_articles/vol_181_papers/181_2020_385.pdf.
    Published • 10.5004/dwt.2020.25110
  16. Rosário-Ferreira, Nícia; Preto, António J.; Melo, Rita; Moreira, Irina S.; Brito, Rui M. M.. Corresponding author: Rosário-Ferreira, Nícia. "The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection". International Journal of Molecular Sciences 21 4 (2020): 1511. http://dx.doi.org/10.3390/ijms21041511.
    10.3390/ijms21041511
  17. Madureira, J.; Leal, J.P.; Botelho, M.L.; Cooper, William J.; Melo, R.. "Radiolytic degradation mechanism of acetovanillone". Chemical Engineering Journal 382 (2020): 122917. http://dx.doi.org/10.1016/j.cej.2019.122917.
    10.1016/j.cej.2019.122917
  18. Magalhães; Machuqueiro; Almeida; Melo; D. S. Cordeiro; Verde; Gümüs; Moreira; D. G. Correia. "Dynamical Rearrangement of Human Epidermal Growth Factor Receptor 2 upon Antibody Binding: Effects on the Dimerization". Biomolecules 9 11 (2019): 706. http://dx.doi.org/10.3390/biom9110706.
    10.3390/biom9110706
  19. João Franco Machado; Rúben D. Silva; Melo R.; João D. G. Correia. "Less Exploited GPCRs in Precision Medicine: Targets for Molecular Imaging and Theranostics". Molecules (2018): http://www.mdpi.com/1420-3049/24/1/49.
    10.3390/molecules24010049
  20. Melo R; Lemos A; Preto AJ; Bueschell B; Matos-Filipe P; Barreto C; Almeida JG; et al. "An overview of antiretroviral agents for treating HIV infection in paediatric population.". Current medicinal chemistry (2018): http://europepmc.org/abstract/med/30182840.
    Published • 10.2174/0929867325666180904123549
  21. Rita Melo; Agostinho Lemos; Antonio J. Preto; Jose G. Almeida; Joao D. G. Correia; Ozge Sensoy; Irina S. Moreira. "Computational Approaches in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapy". Current Topics in Medicinal Chemistry 18 (2018): https://doi.org/10.2174%2F1568026618666180731165222.
    Published • 10.2174/1568026618666180731165222
  22. Agostinho Lemos; Rita Meloc; Antonio J. Preto; Jose G. Almeida; Irina S. Moreira; M. Natalia D. S. Cordeiro. "In silico studies targeting G-protein coupled receptors for drug research against Parkinson’s disease". Current Neuropharmacology 16 (2018): https://doi.org/10.2174%2F1570159x16666180308161642.
    10.2174/1570159x16666180308161642
  23. J. Madureira; L. Barros; R. Melo; S. Cabo Verde; Isabel C.F.R. Ferreira; F.M.A. Margaça. "Degradation of phenolic acids by gamma radiation as model compounds of cork wastewaters". Chemical Engineering Journal (2018): https://doi.org/10.1016%2Fj.cej.2018.02.036.
    10.1016/j.cej.2018.02.036
  24. Madureira, Joana; Melo, Rita; Verde, Sandra Cabo; Matos, Ines; Bernardo, Maria; Noronha, Joao P.; Margaca, Fernanda M. A.; Fonseca, Isabel M.. "Recovery of phenolic compounds from multi-component solution by a synthesized activated carbon using resorcinol and formaldehyde". Water Science and Technology (2018): https://publons.com/wos-op/publon/2081078/.
    10.2166/WST.2017.555
  25. Madureira, Joana; Ceriani, Elisa; Pinhão, Nuno; Marotta, Ester; Melo, Rita; Cabo Verde, Sandra; Paradisi, Cristina; Margaça, Fernanda M.A.. "Oxidation of clofibric acid in aqueous solution using a non-thermal plasma discharge or gamma radiation". Chemosphere 187 (2017): 395-403. http://dx.doi.org/10.1016/j.chemosphere.2017.08.109.
    10.1016/j.chemosphere.2017.08.109
  26. Moreira, Irina S.; Koukos, Panagiotis I.; Melo, Rita; Almeida, Jose G.; Preto, Antonio J.; Schaarschmidt, Joerg; Trellet, Mikael; et al. "SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots". Scientific Reports 7 1 (2017): http://dx.doi.org/10.1038/s41598-017-08321-2.
    Published • 10.1038/s41598-017-08321-2
  27. Madureira, Joana; Melo, Rita; Pimenta, Andreia I.; Verde, Sandra Cabo; Borrely, Sueli I.. Corresponding author: Melo, Rita. "Evaluation of e-beam irradiation effects on the toxicity of slaughterhouse wastewaters". Environmental Technology 39 7 (2017): 873-877. http://dx.doi.org/10.1080/09593330.2017.1313887.
    10.1080/09593330.2017.1313887
  28. Madureira, Joana; Pimenta, Andreia I.; Popescu, Larisa; Besleaga, Alexandra; Dias, Maria Inês; Santos, Pedro M.P.; Melo, Rita; et al. "Effects of gamma radiation on cork wastewater: Antioxidant activity and toxicity". Chemosphere 169 (2017): 139-145. http://dx.doi.org/10.1016/j.chemosphere.2016.11.064.
    10.1016/j.chemosphere.2016.11.064
  29. Moreira, Irina S.; Koukos, Panos; Melo, Rita; Almeida, Jose G.; Preto, Antonio J.; Schaarschmidt, Jorg; Trellet, Mikael; et al. "Spoton: A Machine-Learning Approach for Hot-Spot Determination". Biophysical Journal (2017): https://publons.com/wos-op/publon/3344073/.
    10.1016/J.BPJ.2016.11.284
  30. Madureira, Joana; Ceriani, Elisa; Pinhão, Nuno; Marotta, Ester; Melo, Rita; Verde, Sandra Cabo; Paradisi, Cristina; Margaça, Fernanda M.A.. "Oxidation of clofibric acid in aqueous solution using a non-thermal plasma discharge or gamma radiation". ArXiv (2017): https://publons.com/wos-op/publon/57418470/.
  31. Guerreiro, Duarte; Madureira, Joana; Silva, Telma; Melo, Rita; Santos, Pedro M.P.; Ferreira, Armando; Trigo, Maria João; et al. "Post-harvest treatment of cherry tomatoes by gamma radiation: Microbial and physicochemical parameters evaluation". Innovative Food Science & Emerging Technologies 36 (2016): 1-9. http://dx.doi.org/10.1016/j.ifset.2016.05.008.
    Published • 10.1016/j.ifset.2016.05.008
  32. Melo, Rita; Fieldhouse, Robert; Melo, André; Correia, João; Cordeiro, Maria; Gümüs, Zeynep; Costa, Joaquim; Bonvin, Alexandre; Moreira, Irina. "A Machine Learning Approach for Hot-Spot Detection at Protein-Protein Interfaces". International Journal of Molecular Sciences 17 8 (2016): 1215. http://dx.doi.org/10.3390/ijms17081215.
    10.3390/ijms17081215
  33. Lima, Célia; Madureira, Joana; Carolino, Maria M.; Noronha, João P.; Margaça, Fernanda M. A.; Cabo Verde, Sandra; Melo, Rita. "A Biodegradation Bench Study of Cork Wastewater using Gamma Radiation". Journal of Advanced Oxidation Technologies 19 1 (2016): http://dx.doi.org/10.1515/jaots-2016-0109.
    10.1515/jaots-2016-0109
  34. Lima, Celia; Madureira, Joana; Melo, Rita; Carolino, Maria M.; Noronha, Joao P.; Margaca, Fernanda M. A.; Verde, Sandra Cabo. "Biodegradation Bench Study of Cork Wastewater using Gamma Radiation". Journal of Advanced Oxidation Technologies (2016): https://publons.com/wos-op/publon/7282983/.
  35. Verde, S.C.; Trigo, M.J.; Sousa, M.B.; Ferreira, A.; Ramos, A.C.; Nunes, I.; Junqueira, C.; et al. "Effects of gamma radiation on raspberries: Safety and quality issues". Journal of Toxicology and Environmental Health - Part A: Current Issues 76 4-5 (2013): 291-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876154162&partnerID=MN8TOARS.
    10.1080/15287394.2013.757256
  36. Madureira, J.; Melo, R.; Botelho, M.L.; Leal, J.P.; Fonseca, I.M.; Botelho, M. L.; Leal, J. P.; Fonseca, I. M.. "Effect of ionizing radiation on antioxidant compounds present in cork wastewater". Water Science and Technology 67 2 (2013): 374-379. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874050318&partnerID=MN8TOARS.
    10.2166/wst.2012.544
  37. Oliveira, M.; Pereira, J.; Cabo Verde, S.; Lima, M.G.; Pinto, P.; De Oliveira, P.B.; Junqueira, C.; et al. "Evaluation of potential of gamma radiation as a conservation treatment for blackberry fruits". Journal of Berry Research 3 2 (2013): 93-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888579793&partnerID=MN8TOARS.
    Published • 10.3233/JBR-130050
  38. Melo, R.P.; Leal, J.P.; Botelho, M.L.. "Radiolytic degradation mechanism of gallic acid and its end-products". Rapid Communications in Mass Spectrometry 25 1 (2011): 218-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650081813&partnerID=MN8TOARS.
    Published • 10.1002/rcm.4803
  39. Melo, R.; Leal, J.P.; Takács, E.; Wojnárovits, L.. "Radiolytic degradation of gallic acid and its derivatives in aqueous solution". Journal of Hazardous Materials 172 2-3 (2009): 1185-1192. http://www.scopus.com/inward/record.url?eid=2-s2.0-71749113962&partnerID=MN8TOARS.
    10.1016/j.jhazmat.2009.07.122
  40. Duarte, C.L.; Andrade, D.C.; Melo, R.P.; Nagatomi, H.R.; Mori, M.N.. "Decontamination of Ametryne HDPE packaging using electron beam accelerator". Radiation Physics and Chemistry 78 7-8 (2009): 725-728. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349126547&partnerID=MN8TOARS.
    Published • 10.1016/j.radphyschem.2009.03.067
  41. Melo, R.; Cabo Verde, S.; Branco, J.; Botelho, M.L.. "Gamma radiation induced effects on slaughterhouse wastewater treatment". Radiation Physics and Chemistry 77 1 (2008): 98-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-35448982777&partnerID=MN8TOARS.
    Published • 10.1016/j.radphyschem.2007.03.006
  42. Ruivo, A.; Gomes, C.; Lima, A.; Botelho, M.L.; Melo, R.; Belchior, A.; Pires de Matos, A.. "Gold nanoparticles in ancient and contemporary ruby glass". Journal of Cultural Heritage 9 SUPPL. (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-56849102425&partnerID=MN8TOARS.
    Published • 10.1016/j.culher.2008.08.003
Thesis / Dissertation
  1. Galvão, Rita Lourenço Paiva de Melo, 1979-. "Application of ionizing radiation to persistent organic pollutants decomposition". PhD, 2012. http://hdl.handle.net/10451/7722.
  2. Madureira, Joana Filipa de Paiva dos Santos; Fonseca, Isabel; Melo, Rita. "Estudo do efeito da radiação ionizante na capacidade antioxidante dos compostos presentes na água de processo da indústria corticeira". Master, 2011. http://hdl.handle.net/10362/7098.

Other

Other output
  1. Sterilization of an Electronic Medical Device. Radiosterilization was applied to a medical device with a ¿programmable memory¿ to allow in vivo implantation. Irradiation on a Cobalt-60 facility at 25 kGy at a dose rate of 2kGy/h corrupted the memory. Therefore an alternative sterilization method using UV was developed and validated based on ISO 11737-1 and ISO 14937. These procedures may be useful and effective for research purposes when only. 2010. Reis, Joana; Cabo Verde, Sandra; Capela Silva, Fernando; Frias, Clara; Potes, José; Melo, Rita; Nunes, Inês; et al. http://hdl.handle.net/10174/2761.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/11/28 In silico approach for the design of peptides targeting the RANK-TRAF6 interaction EPI 2023 - XVIII Iberian Peptide Meeting
iMM IST ITQB NOVA (Sesimbra, Portugal)
2017 Contribution of molecular modelling to the development of virus-like particles for breast cancer theranostics Workshop “Inorganic Chemistry meets Medicine”
Technical University of Munich, Institute of Advanced Science (Munique, Germany)
2015 Valorization of cork wastewater: portuguese case study Radiation Treatment of Wastewater for Reuse with Particular Focus on Wastewaters Containing Organic Pollutants
International Atomic Energy Agency (China)
2013 Valorization of industrial wastes using radiation technologies: The Portuguese case studies IAEA technical meeting “Radiation Treatment of Pollutants, Wastewater and Sludges”
International Atomic Energy Agency (Austria)
2012 Application of ionizing radiation on the cork wastewater treatment “Radiation Treatment of Wastewater for Reuse with Particular Focus on Wastewaters Containing Organic Pollutants
International Atomic Energy Agency (South Korea)
2010 Dégradation radiolytique d’acetovanillone dans les solutions aqueuses Journées d’Etudes de la Chimie sous Rayonnement
(France)
2005 Slaughterhouse Sewage Treatment Using Gamma Radiation-Economical Feasibility Study International Nuclear Atlantic Conference
(Santos, Brazil)
2004 Impact of Ionizing Radiation on Slaughterhouse Wastewater Remediation of Polluted Waters and Wastewaters by Radiation Processing project meeting
International Atomic Energy Agency (Varsóvia, Poland)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/02/04 - Current Chemo-radiotherapy versus standard radiotherapy in breast cancer – a computational and biological perspective
Supervisor
Engenharia Biomédica (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/11/01 - Current Radiation and targeted therapy combined approach in metastatic breast and prostate cancers – computational and biological evaluation
Supervisor
ProtoTera PhD programme (PhD)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2023/09/01 - Current Virus like particles as vehicle for the delivery of anticancer therapeutic deep eutectic systems
Supervisor
Biotecnologia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/04/01 - Current Targeting the RANK-TRAF6 interface for bone metastases theranostics
Co-supervisor
Biotecnology doctoral programme (PhD)
Centro de Ciências e Tecnologias Nucleares, Portugal
2023/01/04 - Current In silico evaluation of HER2-virus-like particles
Supervisor
Engenharia Farmacêutica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/11/01 - Current Inhibition of protein-protein interactions in G-Protein Coupled Receptors with novel peptides towards pharmacological activity
Supervisor
Bioorganic Chemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/09/14 - Current HIV-based virus-like particles design and evaluation as a targeted therapy tool
Supervisor of Rafael Cartaxo Travassos
Bioquímica (Master)
Universidade Nova de Lisboa, Portugal
2022/09/04 - Current Virus like particles as vehicle for the delivery of anticancer therapeutic deep eutectic systems
Supervisor
Biotecnologia (Master)
Centro de Ciências e Tecnologias Nucleares, Portugal
2022/07/01 - Current IAESTE PT 2022-28 - "In silico evaluation of HER2-virus-like particles for treating breast cancer in the era of precision medicine"
Supervisor
Chemical engineer (Specialization course)
Universidad Mayor de San Simón, Bolivia
2021/12/01 - 2022/12/13 Design of novel peptides that interact with G-protein coupled receptors
Supervisor
Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/10/01 - 2022/11/23 HIV-based virus-like particles: the next step in targeted therapy
Supervisor
Biotecnologia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/03/02 - 2022/07/15 In silico evaluation of HER2-virus-like particles for treating breast cancer in the era of precision medicine
Supervisor
Engenharia Biológica (Degree)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2021/11/26 Inhibition of protein-protein interactions in G-Protein Coupled Receptors with novel peptides towards pharmacological activity
Supervisor
Mestrado Bolonha em Engenharia Farmacêutica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/01 - 2021/11/19 In silico design of novel peptides for treating cancer through inhibition of the RANK-TRAF6 interaction
Supervisor
Mestrado Bolonha em Engenharia Farmacêutica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/04 - 2021/09/21 Desenvolvimento de particulas do tipo viral para a optimização de novas terapêuticas para o cancro da mama
Supervisor
Engenharia Biomédica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/01 - 2021/06/30 Avaliação In Silico de Partículas Virais Anti-HER2 para o Tratamento do Cancro da Mama na Era da Medicina de Precisão
Supervisor
Engenharia Biomédica (Degree)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021 - 2021 Design of novel peptides that interact with G-protein coupled receptors
Supervisor
Engenharia Farmacêutica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/03/01 - 2020/07/06 Partículas do tipo viral como vetores de fármacos antitumorais para tratamento do cancro da mama
Supervisor
Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/01/21 - 2020/07/02 Design of peptides to interfering with the RANK-TRAF6 axis: an integrated approach
Supervisor
Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/03 - 2018/12 Design of peptides to interfering with the RANK-TRAF6 axis: an integrated approach
Co-supervisor
Ciências de Engenharia Química e Bioquímica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013 - 2013 Radiation Technologies as environmental tools
Supervisor
Erasmus (Other)
Universitatea Alexandru Ioan Cuza, Romania
2013 - 2013 Cork wastewater valorisation: antioxidants extraction by activated carbon
Supervisor
Erasmus (Other)
Politechnika Warszawska, Poland
2011 - 2012 Valorização das águas corticeiras: extracção de antioxidantes
Supervisor
Ciências de Engenharia Química e Bioquímica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010/12 - 2011/12 Estudo do efeito da radiação ionizante na capacidade antioxidante dos compostos presentes na água de processo da indústria corticeira
Supervisor
Ciências de Engenharia Química e Bioquímica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010 - 2011 Avaliação dos antioxidantes presentes nas águas de processo da indústria corticeira
Supervisor
Tecnologia e Segurança Alimentar (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2005 - 2006 Estudo do impacto da radiação ionizante em águas residuais : suiniculturas e indústria de lacticínios
Co-supervisor
Engenharia Agro-Alimentar (Degree)
Instituto Politécnico de Santarém Escola Superior Agrária, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2017 - 2017 Organizing committee of EJIBCE – “Encounter of Young investigators in Computational and Structural Biology”, Portugal (2017 - 2017)
Meeting (Member of the Organising Committee)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013 - 2013 Organization member of Regional Training Course on Regional Training Course on Microbiological Aspects of Sterilization Validation Process, Lisbon, Portugal. (2013 - 2013)
Other (Member of the Organising Committee)
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2012 - 2012 Organization member XVI Journées d´Études de la Chimie sous Rayonnement - JECR 2012, Sines, Portugal. (2012 - 2012)
Meeting (Member of the Organising Committee)
REQUIMTE, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/12/06 In silico evaluation of HER2-virus-like particles for treating breast cancer in the era of precision medicine
Supervisor
Ana Fernandes (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/11/20 HIV-BASED VIRUS-LIKE PARTICLES: DESIGN AND EVALUATION AS A TARGETED THERAPY TOOL
Supervisor
Rafael Cartaxo Travassos (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/11/20 Synthesis of cell-penetrating peptides based on G¿ for the Dopamine-D2R pathway assessment
Supervisor
Inês Teodósio Vicente (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/10/11 Large-scale analysis of genotype-phenotype in relationships of aminomethyltransferase mutations in Nonketotic Hyperglycinemia disease
(Thesis) Main arguer
Mónica Martins Tavares (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022/11/24 Design of novel peptides that interact with G-protein coupled receptors
Supervisor
Francisco Lucas (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/11/23 HIV-based virus-like particles: the next step in targeted therapy
Supervisor
Sofia Alexandra de Albuquerque Martins (Master)
Universidade Nova de Lisboa, Portugal
2022/06/29 Design de novos péptidos dirigidos ao recetor de androgénio no cancro da mama triplo negativo: uma abordagem in silico
(Thesis) Main arguer
Ana Catarina Ramos Pires Pedrosa (Master)
Instituto Superior Técnico Departamento de Engenharia e Gestão, Portugal
2021/11/26 Design of novel peptides that interact with G- protein-coupled receptors
Supervisor
Cátia Filipa Gouveia Rosa (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/11/19 In Silico design of novel peptides for treating cancer through inhibition of the RANK-TRAF6 interaction
Supervisor
Sara Batalha Galhofo Celestino Perdigão (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/09/18 Design of HER2-specific virus-like particles: the next step in targeted therapy
Supervisor
Joana Pinto dos Santos (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/07/07 Transportadores catiónicos de aminoácidos como alvo para radioteranóstica do cancro
(Thesis) Main arguer
Rita Isabel Carvalho Teixeira (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Committee member

Activity description
Role
Institution / Organization
2021/12/20 - Current Member of the 3D-BioInfo Community from BioData.pt. BioData.pt is the Portuguese distributed infrastructure for biological data and the Portuguese ELIXIR node
Member
Universidade de Coimbra, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/07 - Current Molecular dynamics simulation for proteins Summer School in Computational Biology (Outros) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/09/15 - Current Molecular dynamics for lipid membranes and proteins (Outros) Universidade de Coimbra, Portugal
2023/10/20 - 2023/10/20 Molecular Viz Marvels: Dive into the tiny world of molecules (Outros) Universidade de Coimbra, Portugal
2022/12/19 - 2022/12/20 3D-BIOINFO-PT: Intermediate Workshop (Outros) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/09/22 - 2022/09/23 3D-BIOINFO-PT: Introductory Workshop (Outros) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022/09/05 - 2022/09/07 From structure and dynamics to new therapeutic approaches: a computational strategy (Outros) Centro de Ciências e Tecnologias Nucleares, Portugal
2020/09/08 - 2020/09/10 1st C2TN Summer School – “CARISMA 2020” summer school Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2016/05 - 2019/05 Aplicações das tecnologias de radiação RaBBIT doctoral training programme (Curso de doutoramento (conclusão de unidades curriculares)) Universidade Nova de Lisboa Departamento de Física, Portugal
2011 - 2012 assistant professor of analytical chemistry (Curso médio) Instituto Politécnico de Setúbal, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2017 - 2017 Scientific Committee of MOL2NET, International Conference of Multidisciplinary Sciences
Member

Journal scientific committee

Journal title (ISSN) Publisher
2022/05/24 - Current Frontiers in cellular and infection microbiology
2020 - Current Cell (0092-8674) Elsevier
2017 - Current Journal of Hazardous Materials (0304-3894) Elsevier
2017 - Current MOL2NET, International Conference of Multidisciplinary Sciences.

Mentoring / Tutoring

Topic Student name
2022/04/01 - 2022/06/20 Projeto de Investigação MARIA TERESA DUARTE FERREIRA BERTRAND
2022/04/01 - 2022/06/20 Projeto de Investigação BÁRBARA DE CARVALHO LOPES
Distinctions

Award

2021 "Pick yoUR bRain" - Born from Knowledge 2021
Agência Nacional de Inovação SA, Portugal