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Elisabete Silva (ES) graduated in Biology, in 1999 from the Faculty of Sciences of the University of Porto, and obtained her PhD in Biomedicine, in 2011, from the Faculty of Medicine of University of Porto. Her PhD thesis aimed to study the expression and regulation of Na,K-ATPase in aged renal cells. In 2011, she joined the Ageing & Stress group from Institute for Molecular and Cell Biology (IBMC) - University of Porto to proceed as postdoctoral researcher where she studied the role of age-dependent alterations in redox-balance on female fertility. Currently, she is a Researcher in the Ageing & Stress group, at i3S (Porto, Portugal) and an Assistant Professor at COFAC (Faculty of Veterinary Medicine, Lusófona University and IPLuso). ES is also an Adjunct Professor at Health School, Porto Polytechnic Institute. Her research interests are reproductive ageing, oxidative stress, senescence and infertility. Between September 2020 and September 2023 ES was an invited Assistant Physiology Professor at ICBAS/UP. Elisabete Silva has an H index of 14 and a total of 862 citations, according to the system of international reference Scopus. Her scientific career in the field of Physiology and Pharmacology is illustrated by the publication of 32 articles in indexed journals with an impact factor, 15 of which as first or last author, 4 reviews and 2 book chapters; for presenting her work in national and international congresses of reference in her research area; through the participation in 14 research projects, being principal investigator in a funded project and already completed; for the supervision / co-supervision of 8 undergraduate, 7 master and 2 PhD students, in the area of Physiology and Pharmacology - female reproductive system; for the participation in several academic juries; through the peer review of articles submitter to indexed journals with an impact factor; and for the distinction with several prizes.
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Identification

Personal identification

Full name
Elisabete Silva

Citation names

  • Silva, Elisabete

Author identifiers

Ciência ID
EE18-4F58-A7D1
ORCID iD
0000-0002-6736-3469

Addresses

  • Rua Doutor Plácido da Costa, 4200-450, Paranhos, Porto, Portugal (Professional)
  • I3S/IBMC. R. Alfredo Allen, 4200-135, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences
  • Medical and Health Sciences - Basic Medicine - Physiology
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Agrarian Sciences - Veterinary Sciences
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2011/05/01 - 2017/03/31
Concluded
 Age-dependent alterations in redox-balance: role in female reproduction (Pós-doutoramento)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2011
Concluded
 Biomedicina/Biomedicine (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"Expression and regulation of Na,K-ATPase in aged renal cells" (THESIS/DISSERTATION)
 Aprovada com distinção, por unanimidade/Approved w
1999
Concluded
 Biologia, ramo científico-tecnológico, Biologia Animal Aplicada/Biology-Applied Animal Biology (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Estudo da capacidade de transposição de obstáculos pela toupeira-de-água (Galemys Pyrenaicus)" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2017/04/01 - 2023/03/31 Contracted Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2011/07/01 - 2017/03/31 Postdoc (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2003/03/01 - 2005/12/31 Research Trainee (Research) Universidade do Porto Faculdade de Medicina, Portugal
2000/09/01 - 2002/12/31 Research Trainee (Research) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2024/02/24 - Current Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2023/04/01 - Current Invited Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2020/09/22 - 2023/09/21 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Others

Category
Host institution 		Employer
2006/01/01 - 2010/12/31 PhD student with a Fellowship from FCT Universidade do Porto Faculdade de Medicina, Portugal
2000/01/03 - 2000/09/02 Trainee Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Projects

Grant

Designation Funders
2011/07/01 - 2017/03/31 AGE-DEPENDENT ALTERATIONS IN REDOX BALANCE: ROLE IN FEMALE REPRODUCTION
SFRH/BPD/72536/2010
 Fundação para a Ciência e a Tecnologia
Concluded
2011/06/01 - 2017/03/31 Age-dependent alterations in redox-balance: role in female reproduction
SFRH/BPD/72536/2010
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2009/01 - 2012/01 Oxidative stress and genetic markers of cardiovascular risk in hypertension
grant.Provided by PTCRIS: 83204
 Fundação para a Ciência e a Tecnologia
2006/01/01 - 2010/06/30 EXPRESSION AND REGULATION OF NA+,K+-ATPASE IN AGED RENAL CELLS
SFRH / BD / 22876 / 2005
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2006/01/01 - 2010/04/30 EXPRESSION AND REGULATION OF NA+,K+-ATPASE IN AGED RENAL CELLS
SFRH/BD/22876/2005
 Fundação para a Ciência e a Tecnologia
Concluded
2004 - 2004 Renal tubular vectorial sodium transport and regulatory mechanisms
POCTI/CBO/45767/2002
Research Technician Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2003/02/01 - 2003/12 Dopamine and sodium handling in immortalised renal tubular epithelial cells from Spontaneous Hypertensive Rats (SHR) and Wistar Kyoto (WKY) rats
info:eu-repo/grantAgreement/FCT/POCI/35747/PT
Research Technician Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/04 - 2002/12 Fucosiltransferases humanas: organização na membrana e regulação da actividade in vivo
PRAXIS/P/BIO/12072/98
PRAXIS/P/BIO/12072/98
Research Fellow
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
 N/A
Concluded
2000 - 2001 Characyerization of glycosyltransferases involved in mucin O-glycosilation of human gastric mucosa, intestinal metaplasia, gastric carcinoma and cancer cell lines
PRAXIS/P/SAU/14111/1998
Research Fellow
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
1999/01/01 - 1999/12/31 Estudo da capacidade de transposição de obstáculos do rio Ardena pela Toupeira-de-água (Galemys pyrenaicus)
NA
Trainee

Contract

Designation Funders
2021/01/01 - 2025/12/31 Institute for Research and Innovation in Health
LA/P/0070/2020
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/01 - 2024/08/31 Keep fertility at advanced maternal age: on the track of uterine senescent cells
2022.04368.PTDC
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017/04/01 - 2023/03/31 Deficient placentation and development of pregnancy complications - Unveiling the role of protein oxidative modifications
DL57/2016/CP1327/CT0006
Junior Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Ongoing
2017/04/01 - 2023/03/31 Title not available
DL 57/2016/CP1327/CT0006
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/01/02 - 2012/01/01 Oxidative stress and genetic markers of cardiovascular risk in hypertension
PIC/IC/83204/2007
Universidade do Porto Faculdade de Medicina, Portugal

Universidade do Porto Centro de Farmacologia e Biopatologia Química, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Hospital de São João, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2014/01/01 - 2014/12/31 Alterações oxidativas no sangue materno na gravidez normal, associada a ameaça e parto pré-termo
Bebé Vida Project
Other
Concluded
2012/01/01 - 2014/12/01 Redox balance in placental bed as modulator of older women pregnancies
Prize crioestaminal 2011
Post-doc
Concluded
2012/01/01 - 2014/06/30 Aged female diet anti-oxidant supplementation: effect on placental bed and reproductive outcome
PP_IJUP_2011_86
Principal Investigator
Universidade do Porto, Portugal
 Universidade do Porto
2012/01/01 - 2012/12/31 Doença de Parkinson e modulação noradrenérgica: estudo fisiopatológico sobre os efeitos metabólicos induzidos pela estimulação subtalâmica bilateral num modelo animal de Parkinson
NA
Other
Concluded
1998/01/01 - 1998/12/31 Comunidade de Vertebrados Aquáticos e Ribeirinhos do Rio Paiva na Zona de Implantação de uma Barragem
NA
Trainee
Outputs

Publications

Book
  1. Guerreiro, Adriana C; Montenegro, Luís; Pinto, Anabela; Matos, Liliana; Rodrigues, Adriana R; Martins-Bessa, Ana; Almeida, Henrique,; Silva, Elisabete. New highlights into mammalian ovarian aging. 2022.
  2. Silva, E.; Soares-da-Silva, P.. New Insights into the Regulation of Na + ,K + -ATPase by Ouabain. 2012.
    10.1016/B978-0-12-394305-7.00002-1
Book chapter
  1. Silva, Elisabete; Soares-da-Silva, Patrcio. "Renal Redox Balance and Na+, K+-ATPase Regulation: Role in Physiology and Pathophysiology". In Oxidative Stress - Molecular Mechanisms and Biological Effects. InTech, 2012.
    10.5772/34727
Conference abstract
  1. Silva, Nádia; Salazar, Maria; Silva, Elisabete; Neves, Delminda; Almeida, Henrique; Gouveia, Alexandra; Rodrigues, Adriana Raquel. "Melanocortins act as stress-response modulators in adipose tissue of obese mice". Paper presented in IJUP 2020, Porto, 2020.
    Published
Conference paper
  1. "Redox imbalance and cellular senescence: contribution to age- related loss of ovarian fertility". Paper presented in 16th YES (Young European Scientist) Meeting,, Porto, 2021.
    In press
  2. Moreira, Mafalda; Silva, André M.N.; Guedes-Martins, Luís; Saraiva, Joaquim; Almeira, Henrique; Silva, Elisabete; Matos, Liliana. "Using decellularized human uterine samples to assess the influence of the extracellular matrix on the age-related decay on uterine function". 2021.
  3. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Maternal uterine ageing and placentation". Paper presented in 11th Symposium on Metabolism– Ageing & Metabolism, Porto, 2019.
    In press
  4. Timóteo-Ferreira, Filipa; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, Adriana R.; Almeida, Henrique; Silva, Elisabete. "Specific antioxidant effect on ovarian ageing.". Paper presented in 11th Symposium on Metabolism – Ageing & Metabolism, Porto, 2019.
    In press
  5. Nádia Silva; Maria J. Salazar; Elisabete Silva; Delminda Neves; Henrique Almeida; Alexandra M. Gouveia. "Beneficial effects of melanocortins on obesity-related metabolic dysfunction: a focus on the adipose tissue features of premature ageing". Paper presented in 11th Symposium on Metabolism - Ageing & Metabolism, Porto, 2019.
    In press
  6. Timóteo-Ferreira, Filipa; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, Adriana R.; Almeida, Henrique; Silva, Elisabete. "Improvement of age-related ovarian involution by the use of a NADPH-oxidase inhibitor.". Paper presented in 14th Young European Scientist (YES) Meeting, Porto, 2019.
    Published
  7. Timóteo-Ferreira, Filipa; Mendes, Sara; Rocha, AN; Matos, Liliana; Rodrigues, Adriana Raquel; Almeida, H; Silva, Elisabete. "Improvement of the age-related ovarian involution by the use of a NADPH-oxidase inhibitor". Paper presented in 14th YES Meeting, Porto, 2019.
    Published • 10.1097/j.pbj.0000000000000054
  8. Silva, N.; Maria J. Salazar; Silva, Elisabete; Neves, Delminda; Almeida H; Gouveia, Alexandra; Adriana Raquel Rodrigues. "Beneficial effects of melanocortins on obesity-related metabolic dysfunction: a focus on the adipose tissue 10 features of premature ageing". Paper presented in 11th Symposium on Metabolism - Ageing & Metabolism, Porto, 2019.
    Published
  9. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contribute to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published
  10. Timóteo-Ferreira, Filipa; Rocha, N.A.; Mendes, Sara; Rodrigues, Adriana R.; Matos, Liliana; Almeida, Henrique; Silva, Elisabete. "Female reproductive aging: exploring the effects of antioxidant treatment.". Paper presented in 13th Young European Scientist (YES) Meeting, Porto, 2018.
    Published
  11. Silva, Elisabete. "Maternal age and placenta redox changes". 2016.
  12. Silva, Elisabete. "Isolated Systolic Hypertension in Old WKY Rats is Associated With Oxidative Stress and Metabolic Derangements: Effect of Dietary Restriction". 2011.
  13. Silva, Elisabete. "Characterization of the DOPA transporter in an in vitro cellular model of dopaminergic neurons.". 2011.
  14. Silva, Elisabete. "Differential Regulation of Aldosterone Levels by Adiponectin in WKY and SHR". 2011.
  15. Silva, Elisabete. "DIFFERENTIAL EFFECT OF ALPHA2C-ADRENOCEPTORS ON DOPA HANDLING IN NEURONS AND KIDNEY CELLS MAY UNVEIL A POTENTIAL ROLE IN PARKINSON'S DISEASE". 2011.
  16. Silva, Elisabete. "INCREASED OXIDATIVE STRESS AND ALDOSTERONE LEVELS IN AGED WISTAR KYOTO AND SPONTANEOUSLY HYPERTENSIVE RATS: EFFECT OF FOOD RESTRICTION". 2010.
  17. Silva, Elisabete. "OXIDATIVE STRESS AND RENAL MINERALOCORTICOID RECEPTOR EXPRESSION IN AGED WISTAR KYOTO (WKY) AND SPONTANEOUSLY HYPERTENSIVE (SHR) RATS". 2009.
  18. Silva, Elisabete. "Unique Profile in Renal Mineralocorticoid Receptor Expression Change in Aged Spontaneously Hypertensive Rats". 2009.
  19. Silva, Elisabete. "AGING AND NA,K-ATPASE ACTIVITY AND EXPRESSION IN KIDNEY AND JEJUNUM OF NORMOTENSIVE AND SPONTANEOUSLY HYPERTENSIVE RATS". 2009.
  20. Silva, Elisabete. "Effect of Food Restriction on Mineralocorticoid Receptor Expression and Function in Young and Aged Wistar Kyoto Rats". 2009.
  21. Silva, Elisabete. "LACK OF EFFECT OF ANTIOXIDANT THERAPY WITH APOCYNIN, A NADPH OXIDASE INHIBITOR, AGAINST OXIDATIVE STRESS AND ELEVATED BLOOD PRESSURE IN SHR RATS". 2009.
  22. Silva, Elisabete. "IN VITRO CELLULAR AGEING INDUCES CHANGES IN THE EXPRESSION OF RENAL AMINO ACID TRANSPORTER LAT1-4F2HC". 2009.
  23. Silva, Elisabete. "Reactive oxygen species regulate renal Na+, K+-ATPase". 2007.
  24. Silva, Elisabete. "Ouabain induced hypertension and Na+,K+-ATPase in Wistar rats". 2007.
  25. Silva, Elisabete. "Apocynin but not TEMPOL decreases Na+, K+-ATPase alpha 1 subunit expression in opossum kidney cells". 2007.
  26. Silva, Elisabete. "Effect of antioxidants on renal Na,K-atpase activity and expression". 2007.
  27. Silva, Elisabete. "Ouabain stimulates the expression of alpha-1 but not beta-1 subunit of Na+, K+-ATPase in aged OK cells". 2006.
  28. Silva, Elisabete. "Expression of cytoskeleton proteins are related to Na+, K+-ATPase activity in aged OK cells". 2006.
  29. Silva, Elisabete. "Increases in transepithelial vectorial Na+ transport facilitates Na+-dependent L-DOPA transport in renal OK cells". 2006.
  30. Silva, Elisabete. "L-DOPA uptake in aged proximal tubule kidney cells". 2005.
  31. Silva, Elisabete. "Ouabain stimulates alpha 1-Na+,K+-ATPase expression in aged OK cells". 2005.
  32. Silva, Elisabete. "Hydrogen peroxide does not affect Na+,K+-ATPase expression in aged OK cells". 2005.
  33. Silva, Elisabete. "Na+-K+ ATPase function and expression in aged renal epithelial OK cells". 2004.
  34. Silva, Elisabete. "Na+, K+-ATPase increased activity affects other membrane proteins in OK aged cells". 2004.
  35. Silva, Elisabete. "Regulation of aberrant expression of the homeobox genes, Cdx1 and Cdx2, in gastric carcinoma cell lines". 2003.
    10.1016/S0016-5085(03)81491-9
  36. Silva, Elisabete. "Expression of the intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas.". 2002.
Conference poster
  1. Ânia Gomes; Magalhães, Nisa; Beatriz Silva; Maria J. Salazar; Almeida, Henrique; Duarte, Tiago L; Silva, Elisabete; Gouveia, Alexandra; Adriana Raquel Rodrigues. "Iron overload in mice subcutaneous adipose tissue downregulates lipid metabolism and adipocyte browning". Paper presented in Yes meeting 2023, 2023.
  2. Beatriz Silva; Ânia Gomes; Magalhães, Nisa; Maria J. Salazar; Almeida, Henrique; Duarte, Tiago L; Matos, Liliana; et al. "The subcutaneous adipose tissue from HFE-knockout mice accumulates high levels of iron and develops a pro-inflammatory phenotype.". Paper presented in IJUP 2023, 2023.
  3. Ânia Gomes; Magalhães, Nisa; Beatriz Silva; Maria J. Salazar; Almeida, Henrique; Duarte, Tiago L; Silva, Elisabete; Gouveia, Alexandra; Adriana Raquel Rodrigues. "Lipid metabolism in iron overloaded mice adipose tissue". Paper presented in IJUP 2023, 2023.
  4. "Addressing the role of cellular senescence in female fertility". Paper presented in IJUP – Encontro Investigação Jovem, 2021.
  5. "Redox imbalance and cellular senescence: contribution to age-related loss of ovarian fertility". Paper presented in 16th YES (Young European Scientist) Meeting, 2021.
  6. "Ovarian ageing and cellular senescence: an interspecies study". Paper presented in XVII Congresso Internacional Veterinário Montenegro, 2021.
  7. "Ovarian ageing in dog and cat: a preliminary study". Paper presented in Agricultural and veterinary education in Uzbekistan, 2021.
  8. Abreu, David; Teixeira, Ana S.; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Silva, André; Almeida, Henrique; Matos, Liliana; Silva, Elisabete. "Reproductive ovarian ageing: a comparison with the liver". Paper presented in IJUP, 2020.
  9. Teixeira, Ana S.; Abreu, David; Timóteo-Ferreira, Filipa; Gouveia, Alexandra M.; Almeida, Henrique; Rodrigues, Adriana R.; Silva, Elisabete. "Maternal ageing and placenta lipid metabolism: implications on foetal overgrowth". Paper presented in IJUP, 2020.
  10. N. Silva; M.J. Salazar; E. Silva; D. Neves; H. Almeida; A. M. Gouveia; A. R. Rodrigues. "alfa-MSH decreases cellular stress responses in adipose tissue of obese mice". Paper presented in 8th i3S Annual Meeting, 2019.
  11. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Maternal uterine ageing and placentation". Paper presented in 11th Symposium on Metabolism– Ageing & Metabolism., 2019.
  12. Timóteo-Ferreira, Filipa; Mendes, Sara; Rocha, N.A.; Matos, Liliana; Rodrigues, Adriana R.; Almeida, Henrique; Silva, Elisabete. "Apocynin ameliorates age-related ovarian fertility decline in mice". Paper presented in Ageing: models, mechanisms and therapies, 2019.
  13. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Uterine ageing: protein carbonylation and placentation.". Paper presented in Ageing: models, mechanisms and therapies., 2019.
  14. Silva, Nádia; Salazar, Maria; Silva, Elisabete; Neves, Delminda; Almeida, Henrique; Gouveia, Alexandra; Rodrigues, Adriana Raquel. "a-MSH decreases cellular stress responses in ingWAT of obese mice". Paper presented in i3S meeting, 2019.
  15. Rodrigues, Adriana Raquel; Salazar, Maria; Silva, Elisabete; Neves, Delminda; Almeida, Henrique; Gouveia, Alexandra. "Novel protective role of melanocortins in obesity by modulating adipose tissue inflammation, fibrosis and stress-response mechanisms". Paper presented in EMBO workshop - Organ crosstalk in energy balance and metabolic disease, 2019.
  16. Rodrigues, Adriana Raquel; Salazar, Maria; Silva, Elisabete; Neves, Delminda; Almeida, H; Gouveia, Alexandra. "Ageing of adipose tissue: is there a role for melanocortins?". Paper presented in Ageing: models, mechanisms and therapies, 2019.
  17. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein carbonylation may contribute to a defective placentation". Paper presented in 7th i3S annual meeting., 2018.
  18. Timóteo-Ferreira, Filipa; Rocha, N.A.; Mendes, Sara; Rodrigues, Adriana R.; Matos, Liliana; Almeida, Henrique; Silva, Elisabete. "Effect of antioxidant supplementation in female reproductive ageing.". Paper presented in 7th i3S annual meeting, 2018.
  19. Mendes, Sara; Filipa Timóteo; Rodrigues, A.R.; Matos, Liliana; Saraiva, J.; Almeida, H.; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contributor to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, 2018.
  20. Mendes, Sara; Timóteo-Ferreira, Filipa; Rodrigues, Adriana R.; Matos, Liliana; Saraiva, J.; Almeida, Henrique; Guedes-Martins, L.; Silva, Elisabete. "Uterine protein oxidative modifications as a contribute to defective placentation". Paper presented in 13th Young European Scientist (YES) Meeting, 2018.
  21. Timóteo-Ferreira, Filipa; Mendes, Sara; Rocha, NA; Rodrigues, Adriana Raquel; Matos, Liliana; Almeida, H; Silva, Elisabete. "Effects of antioxidant supplementation in female reproductive ageing". Paper presented in 7th i3S Annual Meeting, 2018.
  22. Mendes, Sara; Soares, A.I.; Silveira, S.; Matos, Liliana; Guedes-Martins, L.; Saraiva, J.; Almeida, H.; Silva, Elisabete. "Uterine protein oxidative modifications may condition trophoblast function". Paper presented in 12th Young European Scientist (YES) Meeting, 2017.
  23. Silva, Elisabete. "Ageing and Uterine Oxidative Protein Modifications. New Highlights into Defective Placentation?". Paper presented in 1st Symposium on Ageing Research., 2016.
  24. Silva, Elisabete. "Aged female diet anti-oxidant supplementation: effect on reproductive outcome.". Paper presented in 5º Encontro de Investigação Jovem da Universidade do Porto, 2012.
  25. Silva, Elisabete. "Characterization of the DOPA transporter in an in vitro cellular model of dopaminergic neurons". Paper presented in Annual Meeting of the American Society for Cell Biology, 2011.
  26. Silva, Elisabete. "Differential effect of a2C-adrenoceptors on DOPA handling in neurons and kidney cells may unveil a potential role in Parkinson's disease". Paper presented in 15th Congress of the European Federation of Neurological Societies, 2011.
  27. Silva, Elisabete. "Differential Regulation of Aldosterone Levels by Adiponectin in WKY and SHR". Paper presented in 65rd Annual High Blood Pressure Research Conference, 2011.
  28. Silva, Elisabete. "Isolated Systolic Hypertension in Old WKY Rats is Associated With Oxidative Stress and Metabolic Derangements: Effect of Dietary Restriction". Paper presented in 65rd Annual High Blood Pressure Research Conference, 2011.
  29. Silva, Elisabete. "Increased oxidative stress and aldosterone levels in aged Wistar Kyoto and spontaneously hypertensive rats: effect of food restriction". Paper presented in 20th Annual Meeting of the ESH, 2010.
  30. Silva, Elisabete. "Age related changes in renal expression of oxidant and antioxidant enzymes and oxidative stress markers in SHR and WKY rats". Paper presented in 20th Annual Meeting of the European Society of Hypertension, 2010.
  31. Silva, Elisabete. "Lack of effect of antioxidant therapy with apocynin, a NADPH oxidase inhibitor, against oxidative stress and elevated blood pressure in SHR rats.". Paper presented in 19th Annual Meeting of the ESH, 2009.
  32. Silva, Elisabete. "In vitro cellular ageing induces changes in the expression of renal amino acid transporter LAT1-4F2HC". Paper presented in 19th Annual Meeting of the ESH, 2009.
  33. Silva, Elisabete. "Aging and Na+,K+-ATPase activity and expression in kidney and jejunum of normotensive and spontaneously hypertensive rats.". Paper presented in 19th Annual Meeting of the ESH, 2009.
  34. Silva, Elisabete. "Effect of food restriction on mineralcorticoide receptor expression and function in young and aged wistar Kyoto rats". Paper presented in 63rd Annual High Blood Pressure Research Conference, 2009.
  35. Silva, Elisabete. "Unique profile in renal mineralcorticoide receptor expression change in aged spontaneous hypertensive rats". Paper presented in 63rd Annual High Blood Pressure Research Conference, 2009.
  36. Silva, Elisabete. "Long-term Regulation of Na+,K+-ATPase in Opossum Kidney Cells by Ouabain". Paper presented in 48th Annual Meeting of the ASCB, 2008.
  37. Silva, Elisabete. "Ouabain induced hypertension and Na+,K+-ATPase in Wistar rats". Paper presented in Experimental Biology, 2007.
  38. Silva, Elisabete. "Apocynin but not TEMPOL decreases Na+,K+-ATPase a1 subunit expression in opossum kidney cells.". Paper presented in Experimental Biology, 2007.
  39. Silva, Elisabete. "Effect of antioxidants on renal Na+,K+-ATPase activity and expression". Paper presented in 17th Annual Meeting of the ESH, 2007.
  40. Silva, Elisabete. "Expression of cytoskeleton proteins are related to Na+,K+-ATPase activity in aged OK cells". Paper presented in 16th Annual Meeting of the ESH, 2006.
  41. Silva, Elisabete. "Ouabain stimulates the expression of a1 but not ß1 subunit of Na+,K+-ATPase in aged OK cells". Paper presented in 16th Annual Meeting of the ESH, 2006.
  42. Silva, Elisabete. "Role of Oxidative Stress on the Regulation of Na+,K+-ATPase activity in renal OK cells". Paper presented in 46th Annual Meeting of the ASCB, 2006.
  43. Silva, Elisabete. "Hydrogen peroxidase does not affect Na+,K+-ATPase expression in aged OK cells". Paper presented in 15th Annual Meeting of the ESH, 2005.
  44. Silva, Elisabete. "Ouabain stimulates a1-Na+,K+-ATPase expression in aged OK cells.". Paper presented in 15th Annual Meeting of the ESH, 2005.
  45. Silva, Elisabete. "L-DOPA uptake in aged proximal tubule kidney cells". Paper presented in 15th Annual Meeting of the ESH, 2005.
  46. Silva, Elisabete. "Increases in transepithelial vectorial Na+ transport facilitates Na+-dependent L-DOPA transport in renal OK cells". Paper presented in Glasgow, 2005.
  47. Silva, Elisabete. "Polarized increase in pump-leak coupling in aged renal epithelial OK cells". Paper presented in Experimental Biology, Washington, 2004.
  48. Silva, Elisabete. "Na+,K+-ATPase function and expression in aged renal epithelial OK cells". Paper presented in Experimental Biology, Washington, 2004.
  49. Silva, Elisabete. "Na+,K+-ATPase increased activity affects other membrane proteins in OK aged cells". Paper presented in 4th Congress of the Federation of the EPHAR. Porto, 2004.
  50. Silva, Elisabete. "Effect of cell ageing on transepithelial sodium transport". Paper presented in 4th Congress of the Federation of the European Pharmacological Societies (EPHAR), 2004.
  51. Silva, Elisabete. "Regulation of aberrant expression of the homeobox genes, Cdx1 and Cdx2, in gastric carcinoma cell lines". Paper presented in Digestive Disease Week, San Francisco, 2003.
  52. Silva, Elisabete. "Characterization and regulation of the 5’-flanking region of human muc2 in gastric carcinoma cell lines. Mucins in health and disease.". Paper presented in 7th International Workshop on Carcinoma-associated mucins, Creete, 2003.
  53. Silva, Elisabete. "Expression of intestine-specific transcription factors, Cdx1 and Cdx2, in intestinal metaplasia and gastric carcinomas". Paper presented in Digestive Disease Week. San Francisco, 2002.
  54. Silva, Elisabete. "Polymorphisms of the Lewis enzyme (a1-3/4 fucosyltransferase) and study of its relationship with Helicobacter pylori infection in a portuguese population". Paper presented in European Life Science Organization Meeting. Nice, 2002.
  55. Silva, Elisabete. "Utilização dos Excrementos de Lontra (Lutra lutra) no Estudo da Comunidade de Peixes do Rio Paiva (Bacia do Rio Douro, Portugal) – Resultados preliminares.". Paper presented in IV Jornadas Espanholas de Conservação e Estudo de Mamíferos, Universidade de Sek, Segovia, 1999.
Journal article
  1. Luís Montenegro; Paulo Magalhães; Adriana Costa Guerreiro; Catarina Brandão; Anabela Pinto; Henrique Almeida; Ana Martins-Bessa; E Silva. "The Contribution of the Sheep and the Goat Model to the Study of Ovarian Ageing". Biology (2023): https://www.mdpi.com/2079-7737/12/2/270.
    10.3390/biology12020270
  2. Mendes, Sara; Rosália Sá; Manuel Magalhães; Franklim Marques; Sousa, Mário; Elisabet Silva. Corresponding author: Elisabet Silva. "The role of ROS as a double-edged sword in (In)Fertility: The impact of cancer treatment". Cancers (2022):
    Accepted
  3. F. Timóteo-Ferreira; D. Abreu; S. Mendes; L. Matos; A.R. Rodrigues; H. Almeida; E. Silva. "Redox imbalance in age-related ovarian dysfunction and perspectives for its prevention". Ageing Research Reviews 68 (2021): 101345-101345. https://doi.org/10.1016/j.arr.2021.101345.
    10.1016/j.arr.2021.101345
  4. Mendes, S.; Timóteo-Ferreira, F.; Soares, A.I.; Rodrigues, A.R.; Silva, A.M.N.; Silveira, S.; Matos, L.; et al. "Age-related oxidative modifications to uterine albumin impair extravillous trophoblast cells function". Free Radical Biology and Medicine 152 (2020): 313-322. http://dx.doi.org/10.1016/j.freeradbiomed.2020.03.020.
    10.1016/j.freeradbiomed.2020.03.020
  5. E. Silva; H. Almeida; J. P. Castro. "(In)Fertility and Oxidative Stress: New Insights into Novel Redox Mechanisms Controlling Fundamental Reproductive Processes". Oxidative Medicine and Cellular Longevity (2020): https://doi.org/10.1155/2020/4674896.
    10.1155/2020/4674896
  6. F. Timóteo-Ferreira; S. Mendes; N. A. Rocha; L. Matos; A. R. Rodrigues; H. Almeida; E. Silva. "Apocynin Dietary Supplementation Delays Mouse Ovarian Ageing". Oxidative Medicine and Cellular Longevity (2019): https://doi.org/10.1155/2019/5316984.
    10.1155/2019/5316984
  7. Sara Mendes; Filipa Timóteo-Ferreira; Henrique Almeida; Elisabete Silva. "New Insights into the Process of Placentation and the Role of Oxidative Uterine Microenvironment". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-18. https://doi.org/10.1155/2019/9174521.
    10.1155/2019/9174521
  8. Freitas, C.; Neto, A.C.; Matos, L.; Silva, E.; Ribeiro, Â.; Silva-Carvalho, J.L.; Almeida, H.. "Follicular Fluid redox involvement for ovarian follicle growth". Journal of Ovarian Research 10 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85023164526&partnerID=MN8TOARS.
    10.1186/s13048-017-0342-3
  9. Guedes-Martins, L.; Silva, E.; Gaio, A.R.; Saraiva, J.; Soares, A.I.; Afonso, J.; Macedo, F.; Almeida, H.. "Fetal-maternal interface impedance parallels local NADPH oxidase related superoxide production". Redox Biology 5 (2015): 114-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928229447&partnerID=MN8TOARS.
    10.1016/j.redox.2015.04.007
  10. Guedes-Martins, L.; Gaio, R.; Saraiva, J.; Cerdeira, S.; Matos, L.; Silva, E.; Macedo, F.; Almeida, H.. "Reference Ranges for uterine artery pulsatility index during the menstrual cycle: A cross-sectional study". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84924289939&partnerID=MN8TOARS.
    10.1371/journal.pone.0119103
  11. Silva, E.; Soares, A.I.; Costa, F.; Castro, J.P.; Matos, L.; Almeida, H.. "Antioxidant supplementation modulates age-related placental bed morphology and reproductive outcome in mice". Biology of Reproduction 93 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84943236013&partnerID=MN8TOARS.
    10.1095/biolreprod.114.127746
  12. Guedes-Martins, L.; Matos, L.; Soares, A.; Silva, E.; Almeida, H.. "AGEs, contributors to placental bed vascular changes leading to preeclampsia". Free Radical Research 47 S1 (2013): 70-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881228672&partnerID=MN8TOARS.
    10.3109/10715762.2013.815347
  13. Guimarães, J.; Moura, E.; Silva, E.; Aguiar, P.; Garrett, C.; Vieira-Coelho, M.A.. "Locus coeruleus is involved in weight loss in a rat model of Parkinson's disease: An effect reversed by deep brain stimulation". Brain Stimulation 6 6 (2013): 845-855. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887990923&partnerID=MN8TOARS.
    10.1016/j.brs.2013.06.002
  14. Pinto, V.; Pinho, M.J.; Silva, E.; Simão, S.; Igreja, B.; Afonso, J.; Serrão, M.P.; Gomes, P.; Soares-da-Silva, P.. "Long-term food restriction attenuates age-related changes in the expression of renal aldosterone-sensitive sodium transporters in Wistar-Kyoto rats: A comparison with SHR". Experimental Gerontology 47 8 (2012): 644-653. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863085387&partnerID=MN8TOARS.
    10.1016/j.exger.2012.05.022
  15. Moura, E.; Silva, E.; Serrão, M.P.; Afonso, J.; Kozmus, C.E.P.; Vieira-Coelho, M.A.. "a2c-adrenoceptors modulate L-DOPA uptake in opossum kidney cells and in the mouse kidney". American Journal of Physiology - Renal Physiology 303 7 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84867136982&partnerID=MN8TOARS.
    10.1152/ajprenal.00217.2011
  16. Simão, S.; Gomes, P.; Pinto, V.; Silva, E.; Amaral, J.S.; Igreja, B.; Afonso, J.; et al. "Age-related changes in renal expression of oxidant and antioxidant enzymes and oxidative stress markers in male SHR and WKY rats". Experimental Gerontology 46 6 (2011): 468-474. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955647610&partnerID=MN8TOARS.
    10.1016/j.exger.2011.02.003
  17. Silva, E.; Serrão, M.P.; Soares-Da-Silva, P.. "Age-dependent effect of ouabain on renal Na+,K +-ATPase". Life Sciences 88 15-16 (2011): 719-724. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953291097&partnerID=MN8TOARS.
    10.1016/j.lfs.2011.02.012
  18. Silva, E.; Soares-da-Silva, P.. "Long-term regulation of Na+,K+-ATPase in opossum kidney cells by ouabain". Journal of Cellular Physiology 226 9 (2011): 2391-2397. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958712978&partnerID=MN8TOARS.
    10.1002/jcp.22575
  19. Pinto, V.; Amaral, J.; Silva, E.; Simão, S.; Cabral, J.M.; Afonso, J.; Serrão, M.P.; et al. "Age-related changes in the renal dopaminergic system and expression of renal amino acid transporters in WKY and SHR rats". Mechanisms of Ageing and Development 132 6-7 (2011): 298-304. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961207610&partnerID=MN8TOARS.
    10.1016/j.mad.2011.06.003
  20. Pinho, M.J.; Cabral, J.M.; Silva, E.; Serrão, M.P.; Soares-Da-Silva, P.. "LAT1 overexpression and function compensates downregulation of ASCT2 in an in vitro model of renal proximal tubule cell ageing". Molecular and Cellular Biochemistry 349 1-2 (2011): 107-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952282493&partnerID=MN8TOARS.
    10.1007/s11010-010-0665-5
  21. Silva, E.; Pinto, V.; Simão, S.; Serrão, M.P.; Afonso, J.; Amaral, J.; Pinho, M.J.; Gomes, P.; Soares-da-Silva, P.. "Renal aging in WKY rats: Changes in Na+,K+-ATPase function and oxidative stress". Experimental Gerontology 45 12 (2010): 977-983. http://www.scopus.com/inward/record.url?eid=2-s2.0-78449298646&partnerID=MN8TOARS.
    10.1016/j.exger.2010.09.012
  22. Gomes, P.; Simão, S.; Silva, E.; Pinto, V.; Amaral, J.S.; Afonso, J.; Serrão, M.P.; Pinho, M.J.; Soares-Da-Silva, P.. "Aging increases oxidative stress and renal expression of oxidant and antioxidant enzymes that are associated with an increased trend in systolic blood pressure". Oxidative Medicine and Cellular Longevity 2 3 (2009): 138-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349719148&partnerID=MN8TOARS.
    10.4161/oxim.2.3.8819
  23. Silva, E.; Soares-Da-Silva, P.. "Protein cytoskeleton and overexpression of Na+,K +-ATPase in opossum kidney cells". Journal of Cellular Physiology 221 2 (2009): 318-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-70149113766&partnerID=MN8TOARS.
    10.1002/jcp.21853
  24. Silva, E.; Soares-da-Silva, P.. "Reactive oxygen species and the regulation of renal Na+-K +-ATPase in opossum kidney cells". American Journal of Physiology - Regulatory Integrative and Comparative Physiology 293 4 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-35148890324&partnerID=MN8TOARS.
    10.1152/ajpregu.00425.2007
  25. Silva, E.; Gomes, P.; Soares-da-Silva, P.. "Increases in transepithelial vectorial Na+ transport facilitates Na+-dependent l-DOPA transport in renal OK cells". Life Sciences 79 8 (2006): 723-729. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745645189&partnerID=MN8TOARS.
    10.1016/j.lfs.2006.02.018
  26. Silva, E.; Gomes, P.; Soares-Da-Silva, P.. "Overexpression of Na+/K+-ATPase parallels the increase in sodium transport and potassium recycling in an in vitro model of proximal tubule cellular ageing". Journal of Membrane Biology 212 3 (2006): 163-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947150919&partnerID=MN8TOARS.
    10.1007/s00232-005-7017-5
  27. Almeida, R.; Almeida, J.; Shoshkes, M.; Mendes, N.; Mesquita, P.; Silva, E.; Van Seuningen, I.; et al. "OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells". Journal of Pathology 207 4 (2005): 396-401. http://www.scopus.com/inward/record.url?eid=2-s2.0-29744467037&partnerID=MN8TOARS.
    10.1002/path.1861
  28. Almeida, R.; Silva, E.; Santos-Silva, F.; Silberg, D.G.; Wang, J.; De Bolós, C.; David, L.. "Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas". Journal of Pathology 199 1 (2003): 36-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037221727&partnerID=MN8TOARS.
    10.1002/path.1246
  29. Mesquita, P.; Jonckheere, N.; Almeida, R.; Ducourouble, M.-P.; Serpa, J.; Silva, E.; Pigny, P.; et al. "Human MUC2 Mucin Gene Is Transcriptionally Regulated by Cdx Homeodomain Proteins in Gastrointestinal Carcinoma Cell Lines". Journal of Biological Chemistry 278 51 (2003): 51549-51556. http://www.scopus.com/inward/record.url?eid=2-s2.0-9144240744&partnerID=MN8TOARS.
    10.1074/jbc.M309019200
  30. Serpa, J.; Almeida, R.; Oliveira, C.; Silva, F.S.; Silva, E.; Reis, C.; Le Pendu, J.; et al. "Lewis enzyme (a1-3/4 fucosyltransferase) polymorphisms do not explain the Lewis phenotype in the gastric mucosa of a Portuguese population". Journal of Human Genetics 48 4 (2003): 183-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037908695&partnerID=MN8TOARS.
    10.1007/s10038-003-0007-5
  31. Silva, E.; Teixeira, A.; David, L.; Carneiro, F.; Reis, C.A.; Sobrinho-Simões, J.; Serpa, J.; et al. "Mucins as key molecules for the classification of intestinal metaplasia of the stomach". Virchows Archiv 440 3 (2002): 311-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036121501&partnerID=MN8TOARS.
    10.1007/s004280100531
Journal issue
  1. Silva, Elisabete; Almeida, Henrique; Castro, José Pedro. "(In)Fertility and Oxidative Stress: New Insights into Novel Redox Mechanisms Controlling Fundamental Reproductive Processes". Oxidative Medicine and Cellular Longevity (2019): https://new.hindawi.com/journals/omcl/si/976218/.
    In press • Invited editor
Thesis / Dissertation
  1. Silva, Elisabete. "Expression and Regulation of Na,K-ATPase in renal aged cells / Expressão e Regulação da Na,K-ATPase em Células Renais Envelhecidas". PhD, Universidade do Porto Faculdade de Medicina, 2011. https://hdl.handle.net/10216/55323.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/07/04 Aging of the ovary and the uterus Zoobiquity
Conselho Regional do Sul da Ordem dos Médicos Veterinários (OMV) em conjunto com o Conselho Regional do Sul da Ordem dos Médicos (Lisboa, Portugal)
2022 Ovulation and ovarian senescence as key drivers of ovarian aging Sociedade Portuguesa de Farmacologia – Meeting 2022, Porto, 2022
Universidade do Porto, Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2021 Ovarian redox imbalance and cellular senescence contribution to age- related loss of fertility Jornadas de Biotecnologia para as Ciências da Saúde
Universidade de Trás os Montes e Alto Douro (Vila Real (on line), Portugal)
2021 Cellular senescence and oxidative stress: relevance in age-related fertility loss WebRePRO - I Reproductive Sciences & Fertility Virtual Summit (online)
(Portugal)
2020/02 Melanocortins act as stress-response modulators in adipose tissue of obese mice IJUP
University of Porto (Porto, Portugal)
2019/10 Specific antioxidant effect on ovarian ageing 11th Symposium on Metabolism – Ageing & Metabolism
FMUP (Porto, Portugal)
2019/10 Beneficial effects of melanocortins on obesity-related metabolic dysfunction: a focus on the adipose tissue features of premature ageing 11th Symposium on Metabolism - Ageing & Metabolism
FMUP (Porto, Portugal)
2019/09 Improvement of age-related ovarian involution by the use of a NADPH-oxidase inhibitor. 14th Young European Scientist (YES) Meeting
FMUP (Porto, Portugal)
2019/02 Exploring the role of uterine oxidative protein modifications in defective placentation IJUP
University of Porto (Porto, Portugal)
2019/02 Antioxidant supplementation. A future way for delaying ovarian ageing? IJUP
University of Porto (Porto, Portugal)
2019/02 Unveiling the role of uterine oxidative protein modifications as a contributor to a defective placentation. XLIX Reunião Sociedade Portuguesa de Farmacologia
Portuguese Society of Pharmacology (Porto, Portugal)
2019/02 Effects of antioxidant supplementation in ovarian ageing. XLIX Reunião Sociedade Portuguesa de Farmacologia
Portuguese Society of Pharmacology (Porto, Portugal)
2018/12 The good and the ugly. Effects of antioxidant supplementation in ovarian ageing. Student's Talks
FMUP (Porto, Portugal)
2018/09 Female reproductive aging: exploring the effects of antioxidant treatment. 13th Young European Scientist (YES) Meeting
FMUP (Porto, Portugal)
2018/06 Modulation of trophoblast function by oxidative protein modification. Student’s Talk
FMUP (Porto, Portugal)
2018/02 Exploring the role of oxidative protein modifications in trophoblast function IJUP
University of Porto (Porto, Portugal)
2017 Placental Bed ROS Correlation with Circulatory Impedance: New Insights into Pregnancy Disorders Underlying Mechanisms BIT’s 5 th International Congress on Gynaecology and Obstetrics
(Praga, Czech Republic)
2017 Fibrosis correlates to ovarian and uterine reproductive ageing 10th IJUP meeting
Universidade do Porto (Porto, Portugal)
2016 Antioxidants and female fertility in reproductively aged mice XLVI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2015 Maternal age and placenta redox changes UMIB-Summit 2015
Universidade do Porto, Instituto de Ciências Biomédicas Abel Salazar (Porto, Portugal)
2014 Envelhecimento e fertilidade feminina O Envelhecimento numa Perspectiva Celular e Molecular
Escola Superior de Tecnologia da Saúde do Porto (Vila Nova de Gaia, Portugal)
2014 Aged female diet anti-oxidant supplementation: effect on placental bed and reproductive outcome Encontro de Investigação Jovem - IJUP
Porto University (Porto, Portugal)
2014 Reproductive ageing and antioxidants: effect in uterine function 9th YES Meeting
Students of Faculty of Medicine of Porto University (Porto, Portugal)
2013 Aged female reproduction: role of redox imbalance in placental bed diseases Seminários da Faculdade de Medicina da Universidade do Porto
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2013 O Stress Oxidativo no Leito Placentar Regulação da Sinalização Intracelular V Jornadas Materno Infantis do Hospital Privado da Trofa
Hospital Privado da Troca (Trofa, Portugal)
2013 Epithelial-mesenquimal transition and renal salt-inducible kinase 1 expression in spontaneously hypertensive rats 23rd European Meeting on Hypertension and Cardiovascular Protection
(Milan, Italy)
2013 Aged female reproduction: role of redox imbalance in placental bed diseases Post-Doc Seminars
Instituto de Biologia Molecular e Celular (Porto, Portugal)
2012 Anti-oxidant supplementation and reproductive outcome in aged female mice 7th Young European Scientist Meeting (YES Meeting)
Students from Medical Faculty of Porto University (Porto, Portugal)
2011 Modulation of the aldosterone/mineralcorticoid receptor system in aged WKY and SHR: Effect of long-term food restriction XLI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2011 Age-related changes in renal oxidative stress markers in SHR and WKY rats XLI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2010 Envelhecimento renal: alteração da função da Na, K-ATPase e stress oxidativo Seminário de Bioquímica na Faculdade de Medicina do Porto
Universidade do Porto Faculdade de Medicina (Porto, Portugal)
2007 Effect of antioxidants on renal Na,K-ATPase XXXVIII Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2006 Apocynin decreases Na+-K+-ATPase activity and a1-subunit expression in renal OK cells XXXVII Reunião Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2005 Overexpression of Na+-K+-ATPase a1-subunit parallels the increase in sodium transport and potassium recycling in an in vitro model of proximal tubule cellular ageing XXXVI Reunião da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2004 Na+-K+ ATPase increased activity affects other membrane proteins in OK aged cells 4th Congress of the Federation of EPHAR
(Porto, Portugal)
2004 Effect of cell ageing on transepithelial sodium transport 4th Congress of the Federation of the European Pharmacological Societies (EPHAR)
(Porto, Portugal)
2001 Mucins: Differentiation markers in intestinal metaplasia and gastric carcinoma Simposium on Diagnosis of cancerous and precancerous lesions. X Porto Cancer Meeting.
Instituto de Patologia e Imunologia da Universidade do Porto - IPATIMUP (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/08/01 - Current Female fertility decline: addressing the role of cellular senescence
Supervisor of Adriana Guerreiro
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/01/01 - 2026/12/31 Envelhecimento no ovário e possíveis terapias.
Supervisor
 Doutoramento em Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/10/01 - 2024/09/30 Reproductive Aging in Dog and Cat: a clinical and histological study
Co-supervisor
 Doutoramento em Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/10/01 - 2023/09/30 Exploring the contribution of ovarian senescence in the development of cancer.
Supervisor of Catarina Brandão
 Mestrado em Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2022/10/01 - 2023/07/31 Addressing the role of maternal age and antioxidant supplementation on placenta metabolic profile
Supervisor of Ana Rita Pires Pinheiro
 Mestrado em Biologia Molecular e Celular (Master)
Universidade de Aveiro, Portugal
2020/09/01 - 2021/07/01 Study of oxidative modifications to uterine proteins and their role in placentation
Supervisor of Maria Luísa Guedes de Sousa
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/09/01 - 2021/07/01 New insights into the role of extracellular matrix on human decidualization
Co-supervisor of Mafalda Alexandra da Rocha Moreira
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2019/10/01 - 2020/06 Influence of Extracellular Matrix on Human Uterine Function: a Preliminary Approach
Co-supervisor of Teodora Garcia Lema Figueiredo
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2019/09/20 - 2020/06 Effect of ageing and redox homeostasis on foetal overgrowth
Supervisor of Ana Sofia Magalhães Moreira Teixeira
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2019/09/20 - 2020/06 Cellular senescence and ovarian ageing
Supervisor of David José Silva Abreu
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2018/09/01 - 2019/11/05 Female fertility decline: exploring the role of antioxidants in delaying ovarian ageing
Supervisor of Filipa Timóteo Ferreira
 Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017/09/01 - 2018/12/07 Unveiling novel modulators of trophoblast function
Supervisor of Sara Rafaela Silva Mendes
 Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016/10/01 - 2017/06/19 Female Reproductive Aging: Anti-oxidants and Inflammation
Supervisor of Natalina Alexandra Rocha
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2012/09/01 - 2014/12/10 Anti-oxidant supplementation and reproductive outcome in aged female mice
Supervisor of Ana Isabel Cardoso Soares
 Medicina e Oncologia Molecular (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2014/02/01 - 2014/07/31 Influence of age and antioxidant treatment in the uterine reproductive function
Co-supervisor of Filipe Manuel Amorim Costa
 Bioengenharia (Scientific initiation)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/09/01 - 2013/12/18 Redox changes in aged placental bed: consequences for cell signalling
Supervisor of Sandra Isabel Cunha Silveira
 Genética Molecular (Master)
Universidade do Minho, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2021/02 - Current Session Moderator
Meeting
 52ª Reunião da Sociedade Portuguesa de Farmacologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09 - 2019/09 Proponent and collaborator in the annual UP program "Escola das Ciências da Vida e da Saúde"
Workshop
 Escola das Ciências da Vida e da Saúde
Universidade do Porto, Portugal
2018/09 - 2018/09 Proponent and collaborator in the annual UP program "Escola das Ciências da Vida e da Saúde"
Workshop
 Escola das Ciências da Vida e da Saúde
Universidade do Porto, Portugal
2017/09 - 2017/09 Proponent and collaborator in the annual UP program "Escola das Ciências da Vida e da Saúde" Escola das Ciências da Vida e da Saúde
Universidade do Porto, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/01/24 Preservation of reproductive potential in oncological patient: angiogenesis stimulation of cryopreserved ovarian tissue graft.
(Thesis) Main arguer
 Ana Sofia Fernandes Pais (PhD)
Universidade de Coimbra, Portugal
2022 Epigenetic alterations underlying ovarian ageing
(Thesis) Arguer
 Inês Tavares de Sá Jorge (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 Efeito do aspartame na placentação: estudo in vitro
(Thesis) Arguer
 Helena Isabel Lopes Rodrigues (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020 Study of Protein Oxidation in Different Models of Stress-Induced Premature Senescence.
(Thesis) Arguer
 Paulo Jorge Cardoso Pinheiro (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2019/11/05 Female fertility decline: exploring the role of antioxidants in delaying ovarian ageing
Supervisor
 Filipa Timóteo Ferreira (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/12/07 Unveiling novel modulators of trophoblast function
Supervisor
 Sara Rafaela Silva Mendes (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/06/08 Nutrient transport in first trimester human trophoblasts. Modulation and implications on the process of placentation.
Thesis Member
 Ana Cristina Lima Moreira Correia Branco (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2017/07/10 Efeito do DDE na captação de glicose e ácidos gordos por hepatócitos
(Thesis) Main arguer
 Patrícia Alexandra Néné Soares (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2017/06/19 Female Reproductive Aging: Anti-oxidants and Inflammation
Supervisor
 Natalina Alexandra Rocha (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2014/12/10 Anti-oxidant supplementation and reproductive outcome in aged female mice
Supervisor
 Ana Isabel Cardoso Soares (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2013/12/13 Redox changes in aged placental bed: consequences for cell signalling
Supervisor
 Sandra Isabel Cunha Silveira (Master)
Universidade do Minho, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/02/24 - Current Physiology Osteopatia (Licenciatura) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2024/02/24 - Current Neurociência das Perturbações do Desenvolvimento Terapia Ocupacional (Mestrado integrado) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2024/02/24 - Current Neurociências da Doença Mental Terapia Ocupacional (Mestrado integrado) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2024/02/24 - Current Neurociências do Controlo Motor Terapia Ocupacional (Mestrado integrado) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2023/09/01 - Current Enfermagem pediátrica e obstétrica Licenciatura (Licenciatura) Instituto Politécnico da Lusofonia Escola Superior de Saúde Proteção e Bem-Estar Animal, Portugal
2023/08 - Current Temas emergentes em Fisiologia Veterinária Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2023/03/01 - Current Physiology Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2023/03/01 - Current Reproduction, gyneacology and obstetrics Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2023/03 - Current Reproduction and Obsterics Enfermagem Veterinária (Licenciatura) Instituto Politécnico da Lusofonia Escola Superior de Saúde Proteção e Bem-Estar Animal, Portugal
2021 - Current Changes in renal transmembrane transport in hypertension Metabolismo ¿ Biopatologia e Experimentação (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2016 - Current Changes in renal transmembrane transport in hypertension Metabolismo - Clínica e Experimentação (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Female Reproductive Ageing Medicina e Oncologia Molecular (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Female Reproductive Ageing Medicina e Oncologia Molecular (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Female Reproductive Ageing Medicina Universidade do Porto Faculdade de Medicina, Portugal
2021 - 2023 General Physiology Medicina Veterinária Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2023 Physiology Bioengenharia Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 - 2023 Physiology I Medicina Dentária (Licenciatura) Universidade do Porto Faculdade de Medicina Dentária, Portugal
2020 - 2023 Physiology II Medicina Dentária (Licenciatura) Universidade do Porto Faculdade de Medicina Dentária, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2020 - Current Antioxidants (2076-3921) MDPI AG
2022 - 2022 Molecular Reproduction and Development
2022 - 2022 Biological Research
2021 - 2021 Reproduction
2021 - 2021 Molecular Human Reproduction
2021 - 2021 Life
2019/09 - 2019/12 Molecular Reproduction and Development (1098-2795) Wiley (John Wiley & Sons)
2019/11 - 2019/11 Life Sciences (0024-3205) Elsevier
2019 - 2019/10 Experimental Gerontology (0531-5565) Elsevier
2019/07 - 2019/08 Molecular Human Reproduction (1460-2407) Oxford University Press
2017/08 - 2017/08 Aging Cell (1474-9728) Wiley (Blackwell Publishing)
2017 - 2017 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2016/08 - 2016/10 Experimental Gerontology (0531-5565) Elsevier
2015/08 - 2015/08 Obstetrics and Gynaecology Cases
2015 - 2015 International Journal of Fertility and Sterility

Other jury / evaluation

Activity description Institution / Organization
2019/10/30 - 2019/10/30 Poster evaluation at the 11th Symposium on Metabolism. Universidade do Porto Faculdade de Medicina, Portugal
2019/02/13 - 2019/02/15 Poster evaluation at IJUP 2019 Universidade do Porto, Portugal
2018/10/17 - 2018/10/17 Poster evaluation at the 10th Symposium on Metabolism Universidade do Porto Faculdade de Medicina, Portugal
2017/02/09 - 2017/02/11 Poster evaluation at IJUP 2017 Universidade do Porto, Portugal
2016/02 - 2016/02 Poster evaluation at IJUP 2016 Universidade do Porto, Portugal
2014/02/24 - 2014/02/24 Arguente na Reunião-Entrevista Dra. Ana Cristina Lima Moreira Correia Branco (estudante PD Metabolismo-Clínica e Experimentação). Passagem do 2º para o 3º ano de Doutoramento e inscrição definitiva no programa doutoral. Universidade do Porto Faculdade de Medicina, Portugal
2014/02 - 2014/02 Poster evaluation at IJUP 2014 Universidade do Porto, Portugal
2012/09/12 - 2012/09/12 Vogal (orientadora) na reunião de defesa de Projeto da Dra. Ana Isabel Cardoso Soares (aluna do 1º ano do Mestrado em Medicina e Oncologia Molecular). Universidade do Porto Faculdade de Medicina, Portugal
Distinctions

Award

2006 Travel Grant
2005 Travel Grant

Other distinction

2011 Prémio Crioestaminal 2012 (membro da equipa)
2008 Subsídio para Participação em Congressos Internacionais
Fundação Calouste Gulbenkian, Portugal
2007 Travel Grant
2006 Subsídio para Participação em Congressos Internacionais
Fundação Calouste Gulbenkian, Portugal