???global.info.a_carregar???
Ana Raquel-Cunha has a degree in Applied Biology (2014/2017), a post-graduation in Applied Biochemistry(2017/2018) and a master's degree in Health Sciences by University of Minho (2018/2019). She is, since September 2019, a PhD student in the doctoral program of Health Sciences in University of Minho, developing her dissertation in understanding the role of RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer. Her work is being developed in colaboration with the Molecular Oncology Research Centre integrated in Barretos Cancer Hospital in Brazil. She has 2 published articles, 2 book chapters, 2 oral presentations and 20 conference posters. Additionally, during her path she mentored 5 students. In her curriculum Ciência Vitae the most frequent terms in the context of scientific and technological outputs are: RKIP; lung cancer; biomarker; oncobiology; cancer; molecular targeted therapies.
Read full resume ↓
Identification

Personal identification

Full name
Ana Raquel Ferreira Cunha

Citation names

  • Raquel-Cunha, Ana

Author identifiers

Ciência ID
EE1B-ABAA-6772

Email addresses

  • id8805@alunos.uminho.pt (Professional)

Telephones

Telephone
  • 253604837 (Professional)

Addresses

  • Campus de Gualtar, University of Minho, 4710-057 , Gualtar, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2023/11/13 - 2023/11/17
Attended
 Clinical Research for Researchers: from regulation to practice (Outros)
2CA-Braga, Portugal
 Approved with distinction and honours
2019/09/01 - 2023/09
Ongoing
 Ciências da Saúde (Doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Hospital de Câncer de Barretos Instituto de Ensino e Pesquisa, Brazil
2023/03/13 - 2023/03/31
Attended
 Advanced human in vitro modeling approaches for fundamental and translational research (Curso de doutoramento (conclusão de unidades curriculares))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Approved
2021/03/02 - 2021/03/12
Concluded
 Cell Functional and Phenotypical Analysis: the usefulness of Flow Cytometry and related tools (Curso de doutoramento (conclusão de unidades curriculares))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 approved
2018/09 - 2019/07
Concluded
 Ciências da Saúde (Mestrado)
Major in Master
Universidade do Minho Escola de Medicina, Portugal
"Exploiting RKIP protein as a novel predictor of EGFR targeted therapies response in lung cancer" (THESIS/DISSERTATION)
 18
2019/02/25 - 2019/03/22
Concluded
 Establishment of lung cancer xenograft models (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/01/28 - 2019/02/08
Concluded
 Laboratory Animal Science (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Medicina, Portugal
 16
2018/07/02 - 2018/07/13
Concluded
 Protein Degradation and Trafficking in Health and Disease (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Ciências, Portugal
 19
2017/09 - 2018/07
Concluded
 Bioquímica Aplicada (Pós-Graduação)
Major in Biomedicina
Universidade do Minho Escola de Ciências, Portugal
 17
2018/04/23 - 2018/04/27
Concluded
 Nanoparticles and the immune system: risks and therapeutic opportunities (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Ciências, Portugal
 16
2014/09 - 2016/07
Concluded
 Biologia Aplicada (Licenciatura)
Universidade do Minho Escola de Ciências, Portugal
"A proteína RKIP como um novo preditor de resposta a terapias moleculares dirigidas em cancro do pulmão" (THESIS/DISSERTATION)
 16
Affiliation

Others

Category
Host institution 		Employer
2019/09 - Current PhD Student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
(...)
2018/09 - 2019/07 Master's Student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Escola de Medicina, Portugal
2017/09 - 2018/05 Voluntary Internship Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/06/04 - 2012/06/06 Internship Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Projects

Grant

Designation Funders
2019/09/01 - Current RKIP protein as a novel predictor of EGFR targeted therapy response in lung cancer
SFRH/BD/148199/2019
PhD Student Fellow
Ongoing

Other

Designation Funders
2017/05 - 2018 Exploring RKIP protein as a novel predictor of oncogene targeted therapies in cancer
SFRH/BPD/108351/2015
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Pinheiro, Joana; Gabriela-Freitas, Maria; Fontão, Patrícia; Reis, Rui M.; Martinho, Olga. "Implications of RKIP protein in cancer prognosis and therapy response: A literature update". In Prognostic and Therapeutic Applications of RKIP in Cancer, edited by Benjamin Bonavida; Stavroula Baritaki, 389-414. Elsevier, 2020.
    10.1016/b978-0-12-819612-0.00020-1
  2. Pontes, Olivia; Raquel-Cunha, Ana; Oliveira-Pinto, Sofia; Baltazar, Fatima; Martinho, Olga; Costa, Marta. "Angiogenesis and Chromene-based Antiangiogenic Therapeutic Agents". In Anti-Angiogenesis Drug Discovery and Development: Volume 5, edited by Mariam Mehdi, 151-188. Amsterdam, Netherlands: BENTHAM SCIENCE PUBLISHERS, 2020.
    10.2174/9789811432873120050007
Conference poster
  1. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Mendes, Adriana; Marques, Rui; Reis, Rui Manuel; Martinho, Olga. "Beyond the MAPK Pathway: Unravelling the Importance of RKIP in Lung Adenocarcinoma". Paper presented in EACR 2023 Congress, Innovative Cancer Science, 2023.
  2. Fontão, Patrícia; Mendes, Adriana; Raquel-Cunha, Ana; Martinho, Olga; Reis, Rui M.. "Embryonic T-box transcription factor Brachyury in androgen-dependent prostate cancer models". Paper presented in EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  3. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Mendes, Adriana; Gabriela-Freitas, Maria; Reis, Rui M.; Martinho, Olga. "The implication of RKIP loss in primary resistance to EGFR inhibitors in NSCLC: a novel predictive biomarker?". Paper presented in EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  4. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Gabriela-Freitas, Maria; Reis, Rui Manuel; Martinho, Olga. "Untangling the role of RKIP in NSCLC aggressiveness: an in vitro /in vivo and in silico analysis". Paper presented in II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer, 2021.
  5. Pinheiro, Joana; Fontão, Patrícia; Gabriela-Freitas, Maria; Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Granja, Sara; Martinho, Olga. "Role of RKIP protein in the modulation of lung cancer cell metabolism". Paper presented in II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer, 2021.
  6. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Gabriela-Freitas, Maria; Reis, Rui Manuel; Martinho, Olga. "A proteína RKIP como um novo preditor de resposta a terapias anti-EGFR em cancro do pulmão". Paper presented in 3º Encontro Nacional de Jovens Investigadoresem Oncologia, 2021.
  7. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Reis, Rui Manuel; Martinho, Olga. "Fator de transcrição embrionário T-boxBrachyury como biomarcador de resposta e alvo terapêutico em cancro do pulmão". Paper presented in 3º Encontro Nacional de Jovens Investigadoresem Oncologia, 2021.
  8. Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Fontão, Patrícia; Pinheiro, Joana; Gabriela-Freitas, Maria; Nogueira, Rosete; Reis, Rui Manuel; Martinho, Olga. "Compreender a regulação e sinalização da RKIP no cancro do colo do útero: RKIP/HER loop". Paper presented in 3º Encontro Nacionalde Jovens Investigadoresem Oncologia, 2021.
  9. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Reis, Rui Manuel; Martinho, Olga. "Exploring the predictive andtherapeutic value of the embryonic T-box transcription factor Brachyury in lung cancer". Paper presented in II ASPIC-ASEICA International Meeting -Current Trends in Precision Medicine in Cancer, 2021.
  10. Raquel-Cunha, Ana; Pinheiro, Joana; Diana Cardoso-Carneiro; Gabriela-Freitas, Maria; Fontão, Patrícia; Manuel Reis, RUI; Martinho, Olga. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in EACR 2021 Congress, Innovative Cancer Science: Better Outcomes through Research, 2021.
  11. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Martinho, Olga; Reis, Rui Manuel. "Embryonic T-box transcription factor Brachyury as a predictive biomarker andtherapeutic target in lung cancer". Paper presented in 27th Porto CancerMeeting – Stemness & Metastasis: Advances in Research and Clinical Translation, 2021.
  12. Joana Pinheiro; Maria Gabriela-Freitas; Diana Cardoso-Carneiro; Raquel-Cunha, Ana; Sara Granja; Olga Martinho. "Role of RKIP protein in the modulation of cancer cells metabolism in solid tumors". Paper presented in 6th meeting of ISCaM, 2019.
  13. Diana Cardoso-Carneiro; Patrícia Vaz-Cunha; Rosete Nogueira; Raquel-Cunha, Ana; Ana Carolina Peters; André L. Carvalho; Rui M. Reis; Olga Martinho. "RKIP protein as a potential prognostic, aggressiveness and therapy response biomarker in HNSCC". Paper presented in VII International Symposium on Translational Oncology, 2019.
  14. Ana Raquel-Cunha; Joana Pinheiro; Diana Cardoso-Carneiro; Gabriela Freitas; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in 3rd Annual Meeting CINBIO, 2019.
  15. Raquel-Cunha, Ana; Joana Pinheiro; Diana Cardoso-Carneiro; Gabriela Freitas; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in ICVS Open day 2019, 2019.
  16. Diana Cardoso-Carneiro; Gabriela Freitas; Raquel-Cunha, Ana; Joana Pinheiro; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in ICVS Open Day 2019, 2019.
  17. Ana Raquel-Cunha; Nuno Alves; Diana Cardoso-Carneiro; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer.". Paper presented in SINAL 2018- 9th Meeting on Signal Transduction, 2018.
  18. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer.". Paper presented in SINAL 2018- 9th Meeting on Signal Transduction, 2018.
  19. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in 3rd ASPIC International Congress, 2018.
  20. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer.". Paper presented in Porto Cancer Meeting 2018, 2018.
  21. Ana Raquel-Cunha; Nuno Alves; Diana Cardoso-Carneiro; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer.". Paper presented in ICVS Open Day 2018, 2018.
  22. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in ICVS Open Day 2018, 2018.
  23. Patrícia Vaz-Cunha; Diana Cardoso-Carneiro; Ana Raquel-Cunha; André Lopes Carvalho; Rui M. Reis ; Olga Martinho. "The biological role of RKIP in head and neck cancer: an in vivo and in vitro study". Paper presented in ICVS Open Day 2018, 2018.
Journal article
  1. Gabriela-Freitas; Pinheiro; Raquel-Cunha; Cardoso-Carneiro; Martinho. "RKIP as an Inflammatory and Immune System Modulator: Implications in Cancer". Biomolecules 9 12 (2019): 769. http://dx.doi.org/10.3390/biom9120769.
    10.3390/biom9120769
  2. Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Reis, Rui M.; Martinho, Olga. "Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling". Cells 8 5 (2019): 442. http://dx.doi.org/10.3390/cells8050442.
    10.3390/cells8050442
Thesis / Dissertation
  1. Raquel-Cunha, Ana. "Exploiting RKIP protein as a novel predictor of EGFR targeted therapies response in lung cancer". Master, Universidade do Minho Escola de Medicina, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/10/17 RKIP protein as a novel predictor of EGFR targeted therapy response in Lung Cancer Ciência Falada
School Of Medicine, University of Minho (Braga, Portugal)
2022/03/25 A proteina RKIP como um novo preditor de resposta a terapias direcionadas ao EGFR em câncer do pulmão Seminário em Oncologia
Centro de Pesquisa em Oncologia Molecular- CPOM (Barretos, Brazil)
2019/04/12 RKIP Protein As A Novel Predictor Of EGFR Targeted Therapy In Lung Cancer ICVS Open day 2019
Instituto de Investigação em Ciências da Vida e Saúde (Braga, Portugal)
2018/04/25 RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer Porto Cancer Meeting
(Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017/02 - Current Organizer in XVIII Jornadas de Biologia Aplicada (2017/02)
Meeting (Member of the Organising Committee)
 Universidade do Minho Escola de Ciências, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/03/13 - 2019/03/13 Research on cell signaling and therapy applied to oncobiology
Workshop
 I Jornadas da Ciência
Universidade do Minho Escola de Ciências, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/03 - 2019/03 Participation in activity called "Simpósio do Futuro", giving my testimony as former student of Applied Biology, and my journy until now as a master student and young investigator.
Meeting
 I Jornadas da Ciência
Universidade do Minho Escola de Ciências, Portugal
2018/04 - 2018/04 Oral participant in a “Speed Meeting” to give testimony to describe experience as young investigator.
Meeting
 XIX Jornadas de Biologia Aplicada
Universidade do Minho Escola de Ciências, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/10/18 - 2022/10/18 Cell signalling: Receptor Tyrosine Kinases (RTKs) Molecular basis of cancer (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2022/10/06 - 2022/10/06 Cell signalling: Receptor Tyrosine Kinases (RTKs) Fundamentals in Genetics, Development and Neoplasia (Curso de mestrado (conclusão do curso de especialização)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Mentoring / Tutoring

Topic Student name
2021/12/01 - 2022/02/14 Exploring RKIP chemical induction as a novel adjuvant of EGFR targeted therapy response in lung cancer Ariana Silva
2019/11/04 - 2019/12/13 Study of the influence of HPV infection in RKIP expression in cervical cancer Beatriz Barcellos
2019/04/24 - 2019/06/01 Efeito biológico da expressão da RKIP em linhas celulares de cancro de pulmão Rita Caridade Silva
2018/11 - 2018/12 Raf kinase inhibitor protein (RKIP) as a modulator of oncogene targeted therapies response in Colon Cancer Joana Pinheiro
2018/07/01 - 2018/07/31 Biological effect of RKIP expression in lung cancer cell lines Bruna Araújo

Other jury / evaluation

Activity description Institution / Organization
2024/02/06 - 2024/02/06 Jury of the final report integrated in the Biology Residency Program of the Pio XII Fundation- Barretos Cancer Hospital. Area of focus: Biomedicine in Cancer. Title of the project: "Effects of HERC2 gene ablation in lung squamous cell carcinoma" Project developed by Thayane de Paula Santana and Surpervised by Leticia Ferro Leal (PhD) and Renato Oliveira (PhD). Hospital de Câncer de Barretos Instituto de Ensino e Pesquisa, Brazil
Distinctions

Award

2022 EACR Meeting Bursary Award to attend EACR 2022
European Association For Cancer Research, United Kingdom