Identification
Personal identification
- Full name
- Ana Carolina dos Santos Moreira
Citation names
- Moreira, Ana C.
- Moreira, A. C.
Author identifiers
- Ciência ID
- F110-5842-DCC0
- ORCID iD
- 0000-0003-4049-4781
- Scopus Author Id
- 7201368843
Email addresses
- acarolinasmoreira@gmail.com (Professional)
- ana.s.moreira@ibmc.up.pt (Professional)
Telephones
- Telephone
-
- 220408800 (Professional)
Addresses
- IBMC - Instituto de Biologia Molecular e Celular. Rua Alfredo Allen, 208, 4200-135 P, Porto, Porto, Portugal (Professional)
Websites
- https://www.i3s.up.pt/content/people?id=779&idg=28 (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Biochemistry
- Natural sciences - Biological Sciences - Microbiology
- Medical and Health Sciences - Health Sciences - Infectious Diseases
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Advanced (C1) | Advanced (C1) | Intermediate (B1) | Advanced (C1) | |
French | Advanced (C1) | Advanced (C1) | Intermediate (B1) | Advanced (C1) | |
Spanish; Castilian | Intermediate (B1) | Advanced (C1) | Intermediate (B1) | Intermediate (B1) |
Education
Degree | Classification | |
---|---|---|
2022/09 - 2025
Ongoing
|
Mestrado em Economia e Administração de Empresas (Mestrado)
Universidade do Porto Faculdade de Economia, Portugal
|
|
2013/12/18
Concluded
|
Doutoramento em Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Phytoestrogens as Alternative to the Hormone Replacement Therapy in Menopause: Cellular and Mitochondrial Interactions" (THESIS/DISSERTATION)
|
Aprovada com distinção e Louvor, por unanimidade |
2011/03/21 - 2011/04/01
Concluded
|
Course in Laboratory Animal Science - FELASA Category C (Functions A+B+D) (Outros)
Major in Laboratory Animal Science Specialization
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
|
|
2009/07/17
Concluded
|
Mestrado em Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"CASPASE-INDEPENDENT MECHANISMS IN THE CYTOTOXICITY OF DOXORUBICIN ON EMBRYONIC VENTRICULAR H9c2 CELLS" (THESIS/DISSERTATION)
|
18 |
2008/06/26
Concluded
|
Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Adrenoleukodystrophy: Cotransplantation of Mesenchymal Stem Cells (MSC) and Hematopoietic Stem Cells (HSC) to accelerate
microglia replacement in the Central Nervous System in mouse " (THESIS/DISSERTATION)
|
15 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2019/01/01 - Current | Contracted Researcher (Research) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
2015/04/01 - 2018/12/31 | Postdoc (Research) | Fundação para a Ciência e Tecnologia, Portugal |
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal | ||
2014/02/15 - 2015/03/31 | Postdoc (Research) | Fundação para a Ciência e Tecnologia, Portugal |
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2018/09/17 - Current | Invited Assistant Professor (University Teacher) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2023/04 - Current | IronCell2Cell The macrophage – hepatocyte iron communication during mycobacterial infection
2022.03635.PTDC
Co-Principal Investigator (Co-PI)
|
Fundação para a Ciência e a Tecnologia |
2023/03 - Current | Running Towards an improvement in diagnostics and treatment strategies for TB control (ADVANCE TB)
COST Action A21164,
Researcher
|
European Cooperation in Science and Technology |
2023/02/21 - Current | Iron-sulphur (FeS) clusters: from chemistry to immunology (FeSImmChemNet)
COST Action CA21115
Researcher
European Cooperation in Science and Technology, Belgium
|
European Cooperation in Science and Technology |
2022/06 - Current | The Bone Saaver: the identification of mechanisms and biomarkers of bone loss in patients with cystic fibrosis
003055G221
Researcher
|
Cystic Fibrosis Foundation |
2022/03/01 - Current | Inflammabone - Understanding how chronic infection disrupts the hematopoietic niche leading to osteopenia
KOG-202108-00929
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
European Hematology Association
Ongoing
|
2022/01/15 - Current | IronIC | Infection and iron homeostasis: a new perspective for an old question
EXPL/BIA-BQM/1170/2021
Principal investigator
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021/04/01 - Current | MycoPepTalking: Refining Antimicrobial Peptides with cutting-edge strategies to tackle infections by Nontuberculous Mycobacteria
PTDC/BIA-MIC/3458/2020
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
Fundação para a Ciência e Tecnologia
Ongoing
|
2020/07/09 - 2021/06/08 | Ironing COVID-19 | Finding in the host iron status the signature to predict the severity of the disease
569
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2016/05/01 - 2019/12/31 | Iron hide and seek- does ferritin help the macrophage fight mycobacteria?
PTDC/IMI-MIC/1683/2014
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2015/04 - 2018/12 | Bacterial Infection and iron metabolism (de) regulation: old and new players reveal their roles
SFRH/BPD/101405/2014
Post-doc Fellow
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2016 - 2016 | Structured Programme on Bioengeneering Therapies for Infectious Diseases and Tissue Regeneration
NORTE-01-0145-FEDER-000012
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
European Regional Development Fund
Concluded
|
2014/02 - 2015/02 | Host-Pathogen interactions
ON2-201316-HPI-VI
Post-doc Fellow
|
ON.2
Concluded
|
2010/01/01 - 2013/09/30 | Opening Pandora’s Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria
PTDC/QUI-QUI/101409/2008
Researcher
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2009/10 - 2013/09 | Cellular and Mitochondrial Interactions of Phytoestrogens - Role in Menopause and Breast Cancer
SFRH / BD / 33892 / 2009
PhD Student Fellow
|
Fundação para a Ciência e Tecnologia |
2008/09/01 - 2009/06/01 | Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells - Signalling
Pathways Involved
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2019/01/01 - 2019/12/31 | Institute for Research and Innovation in Health Sciences
UID/BIM/04293/2019
LA/P/0070/2020
Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto, Portugal Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2010/04/01 - 2013/03/31 | A Abertura da Caixa de Pandora Para uma Terapia Activa Anti-cancro da Mama - O Papel do Direccionamento Selectivo da Mitocôndria
PTDC/QUI-QUI/101409/2008
University of Minnesota Twin Cities School of Medicine Duluth Campus, United States
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Coimbra, Portugal Mercer University School of Medicine, United States |
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/01/01 - 2012/12/31 | Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2007/11/01 - 2010/04/30 | Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells: Signaling
Pathways Involved
PTDC/QUI/64358/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Preprint |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2023/05 | Host-mycobacteria interactions: Who will claim the iron throne? | IJUP 2023 - Encontro de Investigação Jovem da Universidade do Porto
Universidade do Porto
|
2023/04/20 | The serum iron-shift during mycobacterial infection |
University of Altinbas - Faculty of Medicine (Instambul, Turkey)
|
2023/03 | IronIC | The serum “iron-shift” during mycobacterial infection | European Iron Club
University Hospital Frankfur (Germany)
|
2023/03 | IronIC | The serum iron-shift during infection |
University of Altinbas - Faculty of Pharmacy
|
2022/10 | A infeção por micobactérias altera o perfil das proteínas que ligam ferro em circulação | Microbiologia
Sociedade Portuguesa de Microbiologia (Portugal)
|
2022/07 | Myeloid H-ferritin is released into circulation and impacts liver iron distribution during mycobacterial infection | European Iron Club
University of Oxford (Oxford, United Kingdom)
|
2022/05 | IronIC | Infection and iron homeostasis: a new perspective for an old question |
i3S - Instituto de Investigação e Inovação em Saúde (Portugal)
|
2021/11 | Iron related Biomarkers predict disease severity in a cohort of Portuguese adult patients during COVID-19 acute infection | 17 Encontro Nacional de Atualização em Infeciologia
Centro Hospitalar do Porto (Porto, Portugal)
|
2021/05/20 | The impact of SARS-CoV-2 infection on the host’s iron homeostasis | XLVI Annual Meeting of the Portuguese Society for Immunology
Portuguese Society for Immunology (Braga, Portugal)
|
2020/01/31 | Role of ferritin in resistance to mycobacterial infection- studies in the mouse model | II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal
Faculdade de Farmácia da Universidade de Lisboa (Lisboa, Portugal)
|
2016/11/03 | Iron metabolism deregulation upon infection: the role of hepcidin | i3S 5th Annual Meeting
i3S - Instituto de Investigação e Inovação em Saúde (Póvoa do Varzim, Portugal)
|
2014/05/02 | Involvement of Mitochondrial Apoptosis-inducing Factor in Doxorubicin-induced Cardiotoxicity | 48th Annual Scientific Meeting of the European Society for Clinical Investigation
European Society for Clinical Investigation (Utrecht, Netherlands)
|
2013/04/20 | Phytoestrogens as alternative to the hormone replacement therapy | 47th Annual Meeting of the European Society of Clinical Investigation
European Society of Clinical Investigation (Albufeira, Portugal)
|
2012/12/19 | Coumestrol as safe and valid alternative for the hormone replacement therapy | X Annual Meeting of Center for Neuroscience and Cell Biology
Center for Neuroscience and Cell Biology, University of Coimbra (Cantanhede, Portugal)
|
2012/06/16 | Modulation of GLUT-1 expression by estrogens at the Blood Brain Barrier: a model to overcome hot flushes in menopause? | Gordon Research Seminar - Barriers of CNS
Gordon Research Conferences (New London, United States)
|
2011/02/11 | Estrogen Dependent Effects on Breast Cancer Cell Motility and Proliferation | Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Coimbra, Portugal)
|
2009/12/02 | Caspase-independent mechanisms in the Cytotoxicity of Doxorubicin on Embryonic Ventricular H9c2 cells, | Reunião Anual da Sociedade Portuguesa de Farmacologia, XXVIII Reunião de Farmacologia Clínica
Sociedade Portuguesa de Farmacologia (Lisbon, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2023/01 - Current | Immune Regulation of Serum Iron Binding Proteins Profile During Mycobacterial Infection
Supervisor
|
Biochemistry |
2022/11 - Current | Serum ferritin release during infection – a role for extracellular vesicles?
Supervisor
|
Biochemistry (Degree) |
2022/11 - Current | The missing link between iron-induced ROS and protection against mycobacterial infections
Supervisor
|
Biochemistry (Degree) |
2022/09 - Current | In vitro functional testing of candidate drugs against dengue fever
Co-supervisor
|
Biochemistry (Master) |
2022/02/21 - Current | Impacto da Infeção por Micobactérias no Perfil de Proteínas Séricas Associadas à Homeostasia do Ferro
Supervisor
|
Lab trainee (Scientific initiation)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2024/01/01 - 2027/12/31 | IronTracker | Iron trafficking and metabolism during infection
Supervisor
|
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2023/01 - 2023/06 | Qual o impacto da infeção crónica na perda de massa óssea em pacientes com fibrosa quística?
Co-supervisor
|
Biologia Celular e Molecular (Degree)
Universidade Nova de Lisboa, Portugal
|
2020/09/28 - 2021/11/26 | New roles for serum iron proteins during infection
Supervisor
|
Mestrado em Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2020/12/14 - 2021/07/23 | Ironing Mycobacterial Infections: the identification and modulation of iron related mechanisms as part of new host-directed
therapies
Supervisor
|
Universidade de Aveiro, Portugal
|
2019/09/10 - 2020/07/10 | Role of infection in host' iron metabolism
Supervisor
|
Bioquímica (Scientific initiation)
Universidade do Porto Faculdade de Ciências, Portugal
|
2019/01/07 - 2019/06/01 | Impact of infection in the iron-binding proteins in the serum
Co-supervisor
|
Biotechnology (Scientific initiation) |
2019/02/10 - 2019/05/21 | The effect of energy balance hormones in the growth of Mycobacterium avium inside macrophages
Co-supervisor
|
Pharmaceutical Care (Master)
Universiteit Antwerpen, Belgium
|
2016/09/01 - 2017/10/27 | Impact of H-ferritin deficiency on macrophage viability and iron status
Supervisor
|
Biomedical Sciences (Master)
Universidade da Beira Interior, Portugal
|
2014/09/01 - 2015/07/17 | Regulation of iron metabolism in different bacterial infections
Supervisor
|
Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2012/04/17 - Current | Participation in the organization of the 47th Annual Meeting of the European Society of Clinical Investigation 2013 (2013/04/17 - 2013/04/20)
Congress
|
European Society for Clinical Investigation, Netherlands |
2009/04/01 - Current | Participation in the organization of the International Courses on Toxicology "Life as matter of fat” (2010/05/11 - 2010/05/14)
Congress
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2009/01/01 - Current | Participation in the organization of the International course in Toxicology "Mitochondria: Between Life and Death" (2009/05/05 - 2009/05/08)
Conference
|
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2015/04/07 - 2015/04/10 | Participação curso avançado
Other
|
Autophagy in health and disease Advanced course
Universidade do Minho, Portugal
|
2014/06/19 - 2014/06/20 | Participação no curso
Workshop
|
Flow Cytometry Fundamentals and Applications
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
2014/04/06 - 2014/04/11 | Participação em curso avançado
Other
|
6th Course on Optical Microscopy Imaging for Biosciences
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
2010/12/15 - 2010/12/17 | Poster: Mitochondrial and Antioxidant effects of selected phytoestrogens on liver and brain fractions
Congress
|
XVII Congress of Portuguese Society of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
|
2010/11/17 - 2010/11/21 | Poster: Antioxidant Effects of selected phytoestrogens in brain and liver Mitochondria
Meeting
|
17th Annual Meeting of Society of Free Radical Biology and Medicine
Society for Redox Biology and Medicine, United States
|
2009/08/23 - 2009/08/26 | Poster: Caspase-independent mechanisms in the Cytotoxicity of Doxorubicin on Embryonic Ventricular H9c2 cells, Society of
Heart and Vascular Metabolism
Conference
|
7th annual scientific sessions Cardiac Metabolism in Health and Disease: Mitochondria and Oxidative Stress
Society for heart and vascular metabolism, United States
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2022/07 | The role of mycobacterial infection in serum iron protein's profile
Supervisor
|
Ana Sofia Martins Ramos (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Faculdade de Ciências, Portugal |
2021/11/26 | New roles for serum iron proteins during infection
Supervisor
|
Inês Simões Alves (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2020/07/10 | Role of infection in host' iron metabolism
Supervisor
|
Eduarda Pinto (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2018/11/16 | The impact of iron overload on hepatobiliary excretion in rodents
(Thesis) Main arguer
|
Catarina Domingues Vasco (Master)
Universidade do Porto, Portugal
|
2017/10/27 | Impact of H-ferritin deficiency on macrophage viability and iron status
Supervisor
|
Gonçalo Mesquita (Master)
Universidade da Beira Interior, Portugal
|
2015/12/03 | The protective role of transcription factor NRF2 against liver injury in human and mouse models of Hereditary Hemochromatosis
(Thesis) Main arguer
|
Andreia Gonçalves (Master)
Universidade do Porto, Portugal
|
2015/07/15 | Regulation of iron metabolism during different bacterial infections
Supervisor
|
Patrícia de Oliveira Ferreira (Master)
Universidade de Aveiro, Portugal
|
Association member
Society Organization name | Role | |
---|---|---|
2023/03 - Current | European Society of Mycobacteriology | Member |
2019/07/16 - Current | European Society for Microbiology and Infectious Diseases | Member |
2019/05/09 - Current | European Federation of Associations of Patients with Haemochromatosis - EFAPH | Secretary |
2019/05/02 - Current | Associação Portuguesa de Hemocromatose | Vice-President |
2016/05/16 - Current | Sociedade Portuguesa de Imunologia | member |
2011/12/16 - 2013/12/31 | European Society for Clinical Investigation | Member |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2018/09/15 - Current | Infection Biology | (Mestrado) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2017/09/17 - Current | General Microbiology | (Licenciatura) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2017/09/17 - Current | Microbiology | (Mestrado integrado) | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2013/10/01 - 2013/12/18 | Curso Avançado Experimental para alunos e professores do Ensino Secundário – Área Biomedicina: Mitocôndrias e Doença - 2013 | (Ensino secundário) | Instituto para a Educação e Cidadania, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
2013/01/01 - 2013/03/30 | Curso Avançado Experimental para alunos e professores do Ensino Secundário – Área Biomedicina: Mitocôndrias e Doença - 2013 | (Ensino secundário) | Instituto para Educação e Cidadania, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2022/01 - Current | LFcin refinery: transforming a crude peptide sequence into valuable antimycobacterial products | Gabriel Oliveira |
2021/01 - Current | NTM: New Tools against nontuberculous Mycobacteria | Clara Milhazes Bento |
2022/09 - 2023/01 | Immune regulation of serum iron proteins | Çagla Senel |
2019 - 2022 | Ana Cristina Magalhaes |
Distinctions
Award
2007 | Mobility fellowship for training
Erasmus, Netherlands
|
Other distinction
2022 | Mobility Fellowship for teaching
Erasmus Plus, Belgium
|
2015 | Bolsa de Pós Doutoramento - SFRH/BPD/101405/2014
Fundação para a Ciência e a Tecnologia, Portugal
|
2014 | ON2-201316-HPI-VI postdoctoral fellowship |
2012 | European Society for Clinical Investigation -Travel Grant |
2012 | Gordon Research Conferences - Travel Grant |
2009 | FAAC - Fundo de Apoio à Comunidade Científica- grant to the 7th Meeting of the Society for Heart and Vascular Metabolism,
August 2009, Padova, Italy
Fundação para a Ciência e a Tecnologia, Portugal
|
2009 | Bolsa de Doutoramento - SFRH / BD / 33892 / 2009
Fundação para a Ciência e a Tecnologia, Portugal
|