Vítor Félix graduated in Applied Chemistry (Organic Chemistry) from the Faculty of Sciences and Technology, New University of Lisbon (FCT-NOVA) in 1986 and completed his PhD in Chemistry from the Instituto Superior Técnico (IST), Technical University of Lisbon (later merged with University of Lisbon) in 1993. Vítor Félix joined University of Aveiro (UA) in 1993 and started his academic career as Assistant Professor in the Department of Chemistry. He was appointed to the Associate Professor position in 2000 and was promoted to Associate Professor with Habilitation in 2008. Vítor Félix's general research lies in the areas of structural chemistry and computational chemistry with focus on complex supramolecular chemistry systems. The structural studies are carried out primarily by single crystal X-ray diffraction. Along the last two decades, Vítor Félix has devoted a significant effort to the structural and energetic characterisation of the recognition of biologically relevant anions (i.e., halides and oxyanions) by a large variety of receptors, including macrocycles, acyclic chiral hosts, and more sophisticated molecular architectures such as interlocked structures, molecular stations and mixed-valence metal hosts, among others. The anion affinity of these receptors, determined by conventional (e.g., hydrogen bonds) and/or non-conventional interactions (such as halogen bonds or chalcogen bonds), was evaluated by the extensive use of Quantum Mechanics calculations and Molecular Dynamics (MD) simulations. Within the broad scope of the anion supramolecular chemistry, another significant research field of activity is the theoretical understanding of the anion traffic through cellular membranes assisted by synthetic molecules. In particular, towards the development of innovative Channel Replacement Therapies for channelopathies, Félix's research group has also been investigating several series of small-drug like molecules with recognised transport activity in lipid vesicles and in Cystic Fibrosis cell line models. These studies were performed with resort to MD simulations in membrane models and quantum descriptors, allowing to establish quantitative structure-transport activity relationships. The MD simulations provided valuable structural and energetic insights on the interaction between the synthetic molecules and membrane models. The commitment with this research field continues with the development of more efficient transporters with the inclusion of pharmaceutical motifs. Vítor Félix's group actively collaborates with experimental groups worldwide on edge research concerning molecular recognition processes. VF co-authored nearly 250 papers with over 6800 citations. His group research activity was supported by four FCT projects in which he was the principal investigator. These projects were funded in a very competitive environment. More detailed information about the Vítor Félix's research activity on molecular modelling and computational biophysics can be found at http://molecular-modeling.dq.ua.pt/ .