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Maria João Ribeiro Peixoto de Queiroz. Completed the Título de Agregado in N/A in 2008/01/08 by Universidade do Minho Escola de Ciências, Doutoramento in Doutoramento em Química Orgânica PhD in Organic Chemistry in 1993 by Universidade do Minho Escola de Ciências and Licenciatura in Ciências Farmacêuticas / Pharmaceutical Sciences in 1986/07/15 by Universidade do Porto Faculdade de Farmácia. Is Coordinating Researcher in Universidade do Minho. Published 150 articles in journals. Has 2 section(s) of books and 2 book(s). Supervised 11 PhD thesis(es). Supervised 17 MSc dissertation(s). Supervised 7 work(s) of course completion of LSc/BSc. Has received 1 awards and/or honors. Participates and/or participated as Principal investigator in 5 project(s) and Researcher in 9 project(s). Works in the area(s) of Exact Sciences with emphasis on Chemical Sciences with emphasis on Organic Chemistry. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Antioxidants/Oxidative stress; di(hetero)arylamines/organic shynthesis; Pharmacological potential; Cell death/apoptosis; amino acids; heterocycles; metal assisted reactions; biological activity and fluorescence; Heterocyclic compounds; Fluorescence; liposomes and membrane proteins; DNA binding ; Antitumorals and antiangiogenics; Molecular modeling; Cell growth factor receptors; magnetic nanoparticles ; magnetoliposomes ; hyperthermia ; controlled drug delivery; catechol based peptides; self-assembly; drug delivery ; medical textiles; Non-proteinogenic amino acids; Photochromic thieno-2H-chromenes; Michael addition; Pd catalized cross-couplings ; PEG400"; Thieno[3,2-b]pyridines"; CuAAC"; 1,4-disubstituted-1,2,3-triazoles"; Organic synthesis, Heterocycles; Targetet drug discovery; C-H activation; Metal Chelates; Gold nanoparticles; Miceles; Natural products; Chemistry; Nutrition; Biological activity; Bioimage; New Tracers; nanoparticles; P2Xreceptors, eATP, Therapeutics; .
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Identification

Personal identification

Full name
Maria João Ribeiro Peixoto de Queiroz

Citation names

  • Queiroz, Maria-João R. P.

Author identifiers

Ciência ID
F212-B8CD-4890
ORCID iD
0000-0002-4322-8035

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
French Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2) Proficiency (C2)
English Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Intermediate (B1) Proficiency (C2) Beginner (A1) Advanced (C1) Intermediate (B1)
Education
Degree Classification
2008/01/08
Concluded
 N/A (Título de Agregado)
Universidade do Minho Escola de Ciências, Portugal
"N/A" (THESIS/DISSERTATION)
 Approved
1993
Concluded
 Doutoramento em Química Orgânica PhD in Organic Chemistry (Doutoramento)
Universidade do Minho Escola de Ciências, Portugal
"Estudos de Síntese em Precursores de Elipticinas/ Studies of synthesis in Ellipticine Precursors" (THESIS/DISSERTATION)
 Distinção e louvor/Distinction and Honors
1986/07/15
Concluded
 Ciências Farmacêuticas / Pharmaceutical Sciences (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"Clinical Analyses performed at National Health Institute-Dr. Ricardo Jorge-Porto" (THESIS/DISSERTATION)
 14 valores
Affiliation

Science

Category
Host institution 		Employer
2009/06/30 - Current Coordinating Researcher (Research) Universidade do Minho, Portugal
Universidade do Minho, Portugal
2001/03/12 - 2008/01/07 Principal Investigator (Research) Universidade do Minho, Portugal
Universidade do Minho, Portugal
1994/01/21 - 2001/03/11 Auxiliary Researcher (Research) Universidade do Minho, Portugal
Universidade do Minho, Portugal
1994/02/02 - 1994/07/31 Auxiliary Researcher (Research) Universidade do Minho, Portugal
Université de Metz, France

Positions / Appointments

Category
Host institution 		Employer
2024/02 - Current Coordinator of the Heterocycles for Societal Challenges research line Universidade do Minho, Portugal
Universidade do Minho Centro de Química, Portugal
2024/02 - Current Member of the management committee of the Chemistry Centre Universidade do Minho, Portugal
Universidade do Minho Centro de Química, Portugal
2022 - Current President of the Coordinating Comission for Researchers' Evaluation in the School of Sciences of University of Minho Universidade do Minho Escola de Ciências, Portugal
Universidade do Minho Escola de Ciências, Portugal
2010/01 - 2015/03 Director of the Centro de Química- Universidade do Minho Universidade do Minho, Portugal
Universidade do Minho Centro de Química, Portugal

Others

Category
Host institution 		Employer
2008/01/08 - 2009/06/29 Principal Investigator with Habilitation Universidade do Minho, Portugal
Universidade do Minho, Portugal
1991/01/21 - 1994/01/20 Assistant Researcher Instituto Nacional de Investigação Científica (INIC), Portugal
Universidade do Minho Departamento de Química, Portugal
1988/02/18 - 1991/01/20 Research Trainnee / Estagiária de Investigação Instituto Nacional de Investigação Científica (INIC), Portugal
Universidade do Minho, Portugal
1986/11/17 - 1988/02/17 Teaching Trainee / Assistente Estagiária Universidade do Minho, Portugal
Universidade do Minho Departamento de Química, Portugal
Projects

Contract

Designation Funders
2022/10 - 2026/10 COST ACTION CA21130- P2X receptors as therapeutic targets (PRESTO)
CA21130
Researcher
Università degli Studi di Ferrara, Italy
 European Commission
Ongoing
2022/10/04 - 2026/09/30 OneHealthdrugs CA21111
CA21111
Researcher
European Union, Belgium
Ongoing
2021 - 2023/06/30 New imaging biomarkers in the assessment of chronic total coronary occlusion (Novos biomarcadores de imagem na avaliação das oclusões coronárias crónicas totais)
BioImage2CTO - 39698
Researcher
Universidade do Minho Centro de Química, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra, Portugal
Agência Nacional de Inovação SA
Concluded
2018/09/15 - 2021/09/14 Self-assembled minimalist peptide hydrogels inspired by mussel adhesive proteins for biomedical applications
PTDC/QUI-QOR/29015/2017
Researcher
Universidade do Minho, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/01 - 2021/06/30 MAGnetoLIposomes for DUal cancer therapy
PTDC/QUI-QFI/28020/2017
Researcher
Universidade do Minho, Portugal

Instituto Politécnico de Bragança, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Ongoing
2016/03/21 - 2020/03/20 Cost Action CA15106 - C-H Activation in Organic Synthesis (CHAOS)
Cost Action CA15106
Researcher
European Union
Concluded
2013 - 2020 Portuguese Nuclear Magnetic Resonance Network - PTNMR
ROTEIRO/0031/2013
PINFRA/22161/2016
ROTEIRO/0031/2013
Principal investigator
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/01/01 - 2015/06/30 n-STeP - Nanostructured systems for Tail
n-STeP NORTE-07-0124-FEDER-000039
Researcher
Universidade do Minho Instituto de Polímeros e Compósitos, Portugal

Universidade do Minho Centro de Química, Portugal
European Regional Development Fund
Concluded
2013/01/01 - 2015/03/31 Projeto Estratégico do Centro de Química da Universidade do Minho
PEst-C/QUI/UI0686/2013
Principal investigator
Universidade do Minho Centro de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/12/24 - 2014/06/23 New antitumor and antiangiogenic heterocyclic compounds: synthesis, molecular modeling, screening of enzymatic inhibition and studies in tumor and endothelial cell lines with tyrosine kinase membrane receptors as targets.
PTDC/QUI-QUI/111060/2009
F-COMP-01-0124-FEDER-015603
Principal investigator
Universidade do Minho, Portugal

Universidade do Minho Centro de Química, Portugal

Instituto Politécnico de Bragança, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2008/11/01 - 2012/07/31 Interaction of new fluorescent biologically active heterocyclic compounds with DNA, lipid membranes and membrane proteins
PTDC/QUI/81238/2006
FCOMP-01-0124-FEDER-007467
Researcher
Universidade do Minho, Portugal

Universidade do Minho Centro de Física, Portugal

Universidade do Minho Centro de Química, Portugal
Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2009/01/01 - 2012/04/30 Antioxidant activity of new di(hetero)arylamines; pharmacological potential against oxidative stress
PTDC/QUI/68382/2006
FCOMP-01-0124-FEDER 007441
Researcher
Universidade do Minho, Portugal

Universidade do Minho Departamento de Biologia, Portugal

Universidade do Minho Centro de Química, Portugal
Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluded
2005/09/01 - 2008/08/31 Metal-assisted synthesis and cyclisation of new biologically active and/or fluorescent aryl and heteroaryl amino acid derivatives
POCI/QUI/59407/2004
Principal investigator
Universidade do Minho, Portugal

Universidade do Minho Centro de Química, Portugal

Instituto Politécnico de Bragança, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2000/10/01 - 2004/03/31 Synthesis of non-proteinogenic amino acids with biological and/or photochromic activities
POCTI/QUI/32689/2000
Researcher
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
1997 - 2005 Bilateral research cooperation protocols with France and Germany
ICCTI/ Embaixada de França em PortugalAcção nº006-B3
Integrated Action Portugal-France F30/03
GRICES-EGIDE 2004-2005
CRUP/DAAD Acção nºA 16-1998
CRUP/DAAD Acção nºA 24-1999
Principal investigator
Concluded
Outputs

Publications

Book
  1. Rodrigues, A.R.O.; Almeida, B.G.; Araújo, J.P.; Queiroz, M.-J.R.P.; Coutinho, P.J.G.; Castanheira, E.M.S.. Magnetoliposomes for dual cancer therapy. 2018.
  2. Abreu, A.S.; Ferreira, P.M.T.; Queiroz, M.-J.R.P.. Palladium-catalysed borylation and suzuki coupling (BSC) to obtain ß-benzo[B]thienyldehydroamino acid derivatives. 2005.
Book chapter
  1. Rodrigues, Ana Rita O.; Almeida, Bernardo G.; Araújo, João P.; Queiroz, Maria-João R.P.; Coutinho, Paulo J.G.; Castanheira, Elisabete M.S.. Corresponding author: Castanheira, Elisabete M.S.. "Magnetoliposomes for dual cancer therapy". In Inorganic Frameworks as Smart Nanomedicines, edited by Elsevier, 489-527. William Andrew, 2018.
    Published
  2. Abreu, Ana S.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Palladium-catalyzed borylation and Suzuki coupling (BSC)to obtain beta-benzo[b]benzothienylamino acids derivatives". In Catalysts for Fine Chemical Synthesis, Volume 3, Metal Catalysed Carbon-Carbon Bond-Forming Reactions, edited by Stanley M. Roberts, Jianliang Xiao, John Whittall and Tom E. Pickett,, 60-64. John Wiley & Sons, Ltd, 2004.
    Published
Conference abstract
  1. Calhelha, Ricardo; Begouin, Agathe; Campos, Joana F.; Queiroz, Maria-João R. P.; Ferreira, Isabel C.F.R.; Abreu, Rui M.V.. "Virtual screening of thieno[3,2-b]pyridine arylthioether (hetero)aryltriazole derivatives as potential tyrosine kinase VEGFR2 inhibitors.". Paper presented in Virtual screening of thieno[3,2-b]pyridine arylthioether (hetero)aryltriazole derivatives as potential tyrosine kinase VEGFR2 inhibitors., Vigo, 2013.
    Published
Conference paper
  1. Ana Rita O. Rodrigues; Matos, Joana O. G.; Queiroz, Maria-João R. P.; Almeida, Bernardo G.; Araújo, João P.; Castanheira, Elisabete M. S.; Coutinho, Paulo. "Magnetoliposomes based on manganese ferrite/gold nanoparticles for applications in cancer therapy". Paper presented in PCNSPA 2018 - Photonic Colloidal Nanostructures: Synthesis, Properties, and Applications, St. Petersburg, 2018.
    Published
Conference poster
  1. Martins, M. F.; Ribeiro, F.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of tetracyclic lactones by Rh(III)-catalyzed C-H activation/ cycloaddition of thieno[2,3-b]quinoline-2-carboxylic acid and alkynes". Paper presented in International Symposium on Heterocyclic Chemistry (ISHC24), 2024.
  2. Martins, Maria F.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of Sonogashira coupling products in the thieno[2,3-b]pyrazine series and cyclizations to tricyclic lactones". Paper presented in 15º Encontro Nacional de Química Orgânica & 8º Encontro Nacional de Química Terapêutica, 2024.
  3. Martins, Maria F.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Parallel synthesis of Suzuki-Miyaura cross-coupling products from thieno[3,2-b]pyridines functionalising both rings,". Paper presented in XXVII Encontro Luso-Galego de Química, 22-24 novembro 2023, Porto, Portugal., 2023.
  4. Guimarães, Rafaela; Abreu, Rui M.V.; Calhelha, Ricardo; Froufe, Hugo J.C.; Carvalho, Ana Maria; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. "Inhibition of the VEGFR-2 tyrosine kinase domain by witd Roman chamomile extracts and phenolic compounds". Paper presented in 2nd Symposium on Medicinal Chemistry of University of Minho, 2015.
  5. Abreu, Rui M.V.; Oludemi, Taofiq; Calhelha, Ricardo; Heleno, Sandrina; Barros, Lillian; Martins, Anabela; Queiroz, Maria-João R. P.; Ferreira, Isabel C.F.R.. "Anti-inflammatory activity of mushrooms extracts, identified phenolic acids and their possible metabolites". Paper presented in III Encontro de Jovens Investigadores. Bragança, 2015.
  6. Machado, Vera; Peixoto, Daniela; Raquel, Costa; Calhelha, Ricardo; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Soares, Raquel; Queiroz, Maria-João R. P.. "Synthesis, molecular Docking and biological evaluation of new 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenylureas as Potent Type II VEGFR-2 Tyrosine Kinase inhibitors". Paper presented in International Symposium of Medicinal Chemistry, 2014.
  7. Queiroz, Maria-João R. P.; Calhelha, Ricardo; Soares, Pedro; Santos, Tiago; Lima, Raquel T.; Campos, Joana F.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena. "New di(hetero)aryl)ethers and Di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on tumor cell lines and non tumor cells, effects on cell cycle and on apoptosis". Paper presented in International Symposium of Medicinal Chemistry, 2014.
  8. Calhelha, Ricardo; Peixoto, Daniela; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. "Synthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine series". Paper presented in 1st Symposium on Medicinal Chemistry, 2013.
  9. Machado, Vera A.; Costa, Raquel; Peixoto, Daniela; Abreu, Rui M.V.; Calhelha, Ricardo; Soares, Raquel; Queiroz, Maria-João R. P.. "New di(heteroaryl)thioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase inhibitors: docking, synthesis, enzymatic and cellular assays". Paper presented in 49th International Conference on Medicinal Chemistry (RICT 2013), Nice, 2013.
  10. Campos, Joana F.; Begouin, Agathe; Peixoto, Daniela; Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.; Calhelha, Ricardo. "Synthesis of new N-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors the tyrosine kinase domain of VEGFR2". Paper presented in 1st Symposium on Medicinal Chemistry, 2013.
  11. Calhelha, Ricardo; Peixoto, Daniela; Soares, Pedro; Ferreira, Isabel C.F.R.; Abreu, Rui M.V.; Queiroz, Maria-João R. P.. "Epidermal growth factor receptor inhibitory activity of new potential antitumor di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series". Paper presented in 1st International Symposium on Profiling, 2013.
  12. Queiroz, Maria-João R. P.; Peixoto, Daniela; Soares, Pedro; Abreu, Rui M.V.; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Costa, Raquel; Soares, Raquel. "Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays". Paper presented in 48th International conference on Medicinal Chemistry. Interfacing Chemical Biology and Drug Discovery, 2012.
  13. Calhelha, Ricardo; Peixoto, Daniela; Soares, Pedro; Ferreira, Isabel C.F.R.; Abreu, Rui M.V.; Queiroz, Maria-João R. P.. "Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series.". Paper presented in 3º Encontro Nacional de Química Terapêutica e 1st Portuguese-Spanish-Brazilian Meeting on Medicinal Chemistry, 2012.
  14. Queiroz, Maria-João R. P.; Peixoto, Daniela; Soares, Pedro; Froufe, Hugo J.C.; Abreu, Rui M.V.; Calhelha, Ricardo; Ferreira, Isabel C.F.R.; Costa, Raquel; Soares, Raquel. "1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays". Paper presented in XXIInd International Symposium on Medicinal Chemistry, 2012.
  15. Calhelha, Ricardo; Peixoto, Daniela; Soares, Pedro; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. "Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines". Paper presented in XXIInd International Symposium on Medicinal Chemistry, 2012.
  16. Peixoto, Daniela; Queiroz, Maria-João R. P.; Abreu, Rui M.V.; Calhelha, Ricardo; Ferreira, Isabel C.F.R.. "Synthesis of novel 1-aryl-3-[2,3- or 4-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors". Paper presented in XXIInd International Symposium on Medicinal Chemistry, 2012.
  17. Abreu, Rui M.V.; Froufe, Hugo J.C.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. "Rational design of thieno[3,2-b]pyridines as potential new VEGFR-2 inhibitors based on improved docking scores.". Paper presented in XII Encontro Nacional da Sociedade Portuguesa de Química: 100 anos de Química em Portugal, 2011.
  18. Peixoto, Daniela; Calhelha, Ricardo; Dias, Sofia; Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. "Methyl 3-[4-(3-arylureido)phenylamino]thieno[3,2-b]pyridine-2-carboxylates as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies". Paper presented in 2nd Iberic Meeting on Medicinal Chemistry: G Protein-Coupled Receptors and Enzymes in Drug Discovery, 2011.
  19. Ferreira, Isabel C.F.R.; Barros, Lillian; Falcão, S.; Vilas-Boas, Miguel; Queiroz, Maria-João R. P.. "Lipid peroxidation inhibition, free radical scavenging activity and electrochemical behaviour of a dihydroxylated di(hetero)arylamine". Paper presented in European meeting of the Society for Free Radical Research International, 2007.
  20. Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.; Barros, Lillian; Abreu, Ana S.; Ferreira, Paula M.T.. "Antioxidant properties of diarylamines derivatives of benzo[b]thiophenes and amino acids". Paper presented in First Iberic Meeting on Medicinal Chemistry - Anticancer Agents, 2007.
Journal article
  1. Lopes, Fábio A. C.; Fernandes, André V. F.; Rodrigues, Juliana M.; Queiroz, Maria-João R. P.; Almeida, Bernardo G.; Pires, Ana; Pereira, André M.; et al. Corresponding author: Coutinho, Paulo J. G.. "Magnetoliposomes Containing Multicore Nanoparticles and a New Antitumor Thienopyridine Compound with Potential Application in Chemo/Thermotherapy". Biomedicines 10 7 (2022): 1547. http://dx.doi.org/10.3390/biomedicines10071547.
    Open access • 10.3390/biomedicines10071547
  2. Ribeiro, Beatriz C.; Alvarez, Cristina A. R.; Alves, Bárbara C.; Rodrigues, Juliana M.; Queiroz, Maria-João R. P.; Almeida, Bernardo G.; Pires, Ana; et al. Corresponding author: Castanheira, Elisabete M. S.. "Development of Thermo- and pH-Sensitive Liposomal Magnetic Carriers for New Potential Antitumor Thienopyridine Derivatives". Materials 15 5 (2022): 1737. http://dx.doi.org/10.3390/ma15051737.
    Open access • 10.3390/ma15051737
  3. Rio, Irina; Rodrigues, Ana; Rodrigues, Juliana; Queiroz, Maria-João R. P.; Calhelha, R.; Ferreira, Isabel; Almeida, Bernardo; et al. Corresponding author: Coutinho, Paulo. "Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy". Pharmaceutics 13 11 (2021): 1905. http://dx.doi.org/10.3390/pharmaceutics13111905.
    Open access • 10.3390/pharmaceutics13111905
  4. Rodrigues, Juliana M.; Calhelha, Ricardo C.; Nogueira, António; Ferreira, Isabel C. F. R.; Barros, Lillian; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of Novel Methyl 7-[(Hetero)arylamino]thieno[2,3-b]pyrazine-6-carboxylates and Antitumor Activity Evaluation: Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Toxicity in Non-Tumor Cells". Molecules 26 16 (2021): 4823. http://dx.doi.org/10.3390/molecules26164823.
    10.3390/molecules26164823
  5. Rodrigues, Juliana M.; Cendón, Borja; Gulías, Moisés; Mascareñas, José Luis; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Rhodium(III)-Catalyzed Formal Cycloaddition between Thienopyridine/Thienopyrazine Carboxylic Acids and Alkynes, Triggered by C-H Activation". European Journal of Organic Chemistry 2021 22 (2021): 3234-3240. http://dx.doi.org/10.1002/ejoc.202100439.
    10.1002/ejoc.202100439
  6. Bruna R. Silva; Rita Rebelo; Juliana M. Rodrigues; Cristina P. R. Xavier; M. Helena Vasconcelos; Maria-João R. P. Queiroz. Corresponding author: Maria-João R. P. Queiroz. "Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic Membrane (CAM) with a Triple Negative Breast Cancer Cell Line". Molecules 26 6 (2021): 1594-1594. https://doi.org/10.3390/molecules26061594.
    Published • 10.3390/molecules26061594
  7. Rodrigues, Juliana M.; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Application of PEG400 in the one-pot synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines via SNAr and Cu(I)-Catalyzed Azide-Alkyne Cycloaddition and preliminary evaluation of their anti-tumour activity". Tetrahedron Letters 61 22 (2020): 151900. http://dx.doi.org/10.1016/j.tetlet.2020.151900.
    10.1016/j.tetlet.2020.151900
  8. Pereira, Daniela S. M.; Cardoso, Beatriz D.; Rodrigues, Ana R. O.; Amorim, Carlos O.; Amaral, V. S.; Almeida, Bernardo G.; Queiroz, Maria-João R. P.; et al. Corresponding author: Castanheira, Elisabete M. S.. "Magnetoliposomes Containing Calcium Ferrite Nanoparticles for Applications in Breast Cancer Therapy". Pharmaceutics 11 9 (2019): 477. http://dx.doi.org/10.3390/pharmaceutics11090477.
    10.3390/pharmaceutics11090477
  9. Rodrigues, Juliana M.; Buisson, Pierre; Pereira, Joana M.; Pinheiro, Inês M.; Fernández-Marcelo, Tamara; Vasconcelos, M. Helena; Berteina-Raboin, Sabine; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of novel 8-(het)aryl-6H-pyrano[4',3':4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation". Tetrahedron 75 10 (2019): 1387-1397. http://dx.doi.org/10.1016/j.tet.2019.01.054.
    10.1016/j.tet.2019.01.054
  10. Rodrigues, Ana Rita O.; Matos, Joana; Nova Dias, Armando; Almeida, Bernardo G.; Pires, Ana; Pereira, André; Araújo, João; et al. Corresponding author: Coutinho, Paulo. "Development of Multifunctional Liposomes Containing Magnetic/Plasmonic MnFe2O4/Au Core/Shell Nanoparticles". Pharmaceutics 11 1 (2019): 10. http://dx.doi.org/10.3390/pharmaceutics11010010.
    Published • 10.3390/pharmaceutics11010010
  11. Veloso, Sérgio R. S.; Magalhães, Carlos A. B.; Rodrigues, Ana Rita O.; Vilaça, H.; Queiroz, Maria-João R. P.; Martins, José A.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.; Castanheira, Elisabete M. S.. Corresponding author: Castanheira, Elisabete M. S.. "Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers". Physical Chemistry Chemical Physics 21 20 (2019): 10377-10390. https://doi.org/10.1039/C9CP00352E.
    Published • 10.1039/C9CP00352E
  12. Campos, Joana; Queiroz, Maria-João R. P.; Berteina-Raboin, Sabine. Corresponding author: Berteina-Raboin, Sabine. "Synthesis of New Annulated Pyrazinothienotriazolopyrimidinones and Triazolylthienopyrazines". Synthesis 50 05 (2018): 1159-1165. http://dx.doi.org/10.1055/s-0036-1589136.
    10.1055/s-0036-1589136
  13. Campos, Joana; Queiroz, Maria-João R. P.; Berteina-Raboin, Sabine. Corresponding author: Berteina-Raboin, Sabine. "The First Catalytic Direct C-H Arylation on C2 and C3 of Thiophene Ring Applied to Thieno-Pyridines, -Pyrimidines and -Pyrazines". Catalysts 8 4 (2018): 137. http://dx.doi.org/10.3390/catal8040137.
    Published • 10.3390/catal8040137
  14. Rodrigues, Ana Rita O.; Mendes, Pedro M.F.; Silva, Pedro M.L.; Machado, V.A.; Almeida, Bernardo G.; Araújo, J.P.; Queiroz, Maria-João R. P.; Castanheira, Elisabete M.S.; Coutinho, Paulo J.G.. Corresponding author: Coutinho, Paulo J.G.. "Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug active against breast cancer". Colloids and Surfaces B: Biointerfaces 158 (2017): 460-468. http://dx.doi.org/10.1016/j.colsurfb.2017.07.015.
    Published • 10.1016/j.colsurfb.2017.07.015
  15. Campos, Joana F.; Queiroz, Maria-João R. P.; Berteina-Raboin, Sabine. Corresponding author: Berteina-Raboin, Sabine. "Synthesis of New Thieno[3,2-b ]pyridines and Thieno[2,3-b ]pyrazines by Palladium Cross-Coupling.". ChemistrySelect 2 24 (2017): 6945-6948. http://dx.doi.org/10.1002/slct.201701054.
    Published • 10.1002/slct.201701054
  16. Rodrigues, Ana Rita O.; Almeida, B. G.; Rodrigues, Juliana M.; Queiroz, Maria-João R. P.; Calhelha, R. C.; Ferreira, Isabel C. F. R.; Pires, A.; et al. Corresponding author: Castanheira, Elisabete M. S.. "Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-arylamines: photophysical and biological studies". RSC Advances 7 25 (2017): 15352-15361. http://dx.doi.org/10.1039/c7ra00447h.
    10.1039/c7ra00447h
  17. Sobral, Filipa; Sampaio, Andreia; Falcão, Soraia; Queiroz, Maria-João R. P.; Calhelha, Ricardo C.; Vilas-Boas, Miguel; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Chemical characterization, antioxidant, anti-inflammatory and cytotoxic properties of bee venom collected in Northeast Portugal". Food and Chemical Toxicology 94 (2016): 172-177. http://dx.doi.org/10.1016/j.fct.2016.06.008.
    Published • 10.1016/j.fct.2016.06.008
  18. Machado, Vera A.; Peixoto, Daniela; Queiroz, Maria-João R. P.; Soares, Raquel. Corresponding author: Soares, Raquel. "Antiangiogenic 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas Inhibit MCF-7 and MDA-MB-231 Human Breast Cancer Cell Lines Through PI3K/Akt and MAPK/Erk Pathways". Journal of Cellular Biochemistry 117 12 (2016): 2791-2799. http://dx.doi.org/10.1002/jcb.25580.
    Published • 10.1002/jcb.25580
  19. Rodrigues, Juliana M.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Efficient One-Pot Synthesis of Alkyl 3-[4-(Aryl or Heteroaryl)-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridine-2-carboxylates by Click Cu(I)-Catalyzed Azide-Alkyne Cycloaddition". Synthesis 48 17 (2016): 2904-2910. http://dx.doi.org/10.1055/s-0035-1562093.
    Published • 10.1055/s-0035-1562093
  20. Pina, J.; Queiroz, M.-J. R. P.; Seixas de Melo, J.. Corresponding author: Pina, J.. "Effect of substitution on the ultrafast deactivation of the excited state of benzo[b]thiophene-arylamines". Photochemical & Photobiological Sciences 15 8 (2016): 1029-1038. http://dx.doi.org/10.1039/c6pp00140h.
    Published • 10.1039/c6pp00140h
  21. Abreu, Ana S.; Hermenegildo, Bruno F. C.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.; Castanheira, Elisabete M. S.. Corresponding author: Castanheira, Elisabete M. S.. "Interaction of fluorescent quinolin-2-one and coumarin derivatives including dipeptides with lipid bilayers". RSC Advances 6 76 (2016): 72141-72148. http://dx.doi.org/10.1039/c6ra14376h.
    10.1039/c6ra14376h
  22. Rodrigues, Ana Rita O.; Ramos, José M. F.; Gomes, I. T.; Almeida, Bernardo G.; Araújo, J. P.; Queiroz, Maria-João R. P.; Coutinho, Paulo J. G.; Castanheira, Elisabete M. S.. Corresponding author: Castanheira, Elisabete M. S.. "Magnetoliposomes based on manganese ferrite nanoparticles as nanocarriers for antitumor drugs". RSC Advances 6 21 (2016): 17302-17313. http://dx.doi.org/10.1039/c5ra27058h.
    10.1039/c5ra27058h
  23. Guimarães, Rafaela; Calhelha, Ricardo C.; Froufe, Hugo J. C.; Abreu, Rui M. V.; Carvalho, Ana Maria; Queiroz, Maria-João R. P.; Ferreira, Isabel C. F. R.. Corresponding author: Ferreira, Isabel C. F. R.. "Wild Roman chamomile extracts and phenolic compounds: enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase". Food & Function 7 1 (2016): 79-83. http://dx.doi.org/10.1039/c5fo00586h.
    10.1039/c5fo00586h
  24. Pires, Tânia; Dias, Maria; Calhelha, Ricardo; Carvalho, Ana; Queiroz, Maria-João R. P.; Barros, Lillian; Ferreira, Isabel. Corresponding author: Ferreira, Isabel. "Bioactive Properties of Tabebuia impetiginosa-Based Phytopreparations and Phytoformulations: A Comparison between Extracts and Dietary Supplements". Molecules 20 12 (2015): 22863-22871. http://dx.doi.org/10.3390/molecules201219885.
    10.3390/molecules201219885
  25. Barros, Lillian; Calhelha, Ricardo C.; Queiroz, Maria-João R. P.; Santos-Buelga, Celestino; Santos, Elândia A.; Regis, Wiliam C.B.; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds". Industrial Crops and Products 76 (2015): 318-322. http://dx.doi.org/10.1016/j.indcrop.2015.05.086.
    10.1016/j.indcrop.2015.05.086
  26. Vilaça, Helena; Hortelão, Ana C. L.; Castanheira, Elisabete M. S.; Queiroz, Maria-João R. P.; Hilliou, Loic; Hamley, Ian W.; Martins, José A.; Ferreira, Paula M. T.. Corresponding author: Ferreira, Paula M. T.. "Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers". Biomacromolecules 16 11 (2015): 3562-3573. http://dx.doi.org/10.1021/acs.biomac.5b01006.
    Published • 10.1021/acs.biomac.5b01006
  27. Machado, Vera A.; Peixoto, Daniela; Costa, Raquel; Froufe, Hugo J.C.; Calhelha, Ricardo C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Soares, Raquel; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors". Bioorganic & Medicinal Chemistry 23 19 (2015): 6497-6509. http://dx.doi.org/10.1016/j.bmc.2015.08.010.
    10.1016/j.bmc.2015.08.010
  28. Taofiq, Oludemi; Calhelha, Ricardo C.; Heleno, Sandrina; Barros, Lillian; Martins, Anabela; Santos-Buelga, Celestino; Queiroz, Maria-João R. P.; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: Screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives". Food Research International 76 (2015): 821-827. http://dx.doi.org/10.1016/j.foodres.2015.07.044.
    10.1016/j.foodres.2015.07.044
  29. Heleno, Sandrina A.; Barros, Lillian; Martins, Anabela; Queiroz, Maria João R.P.; Morales, Patricia; Fernández-Ruiz, Virginia; Ferreira, Isabel C.F.R.. "Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species". LWT - Food Science and Technology 63 1 (2015): 475-481. http://dx.doi.org/10.1016/j.lwt.2015.03.040.
    Published • 10.1016/j.lwt.2015.03.040
  30. Heleno, Sandrina A.; Ferreira, Raíssa Carolina; Antonio, Amilcar L.; Queiroz, Maria-João R.P.; Barros, Lillian; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland". Food Bioscience 11 (2015): 48-55. http://dx.doi.org/10.1016/j.fbio.2015.04.006.
    Published • 10.1016/j.fbio.2015.04.006
  31. Ferreira, Isabel C.F.R.; Heleno, Sandrina A.; Reis, Filipa S.; Stojkovic, Dejan; Queiroz, Maria João R.P.; Vasconcelos, M. Helena; Sokovic, Marina. "Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities". Phytochemistry 114 (2015): 38-55. http://dx.doi.org/10.1016/j.phytochem.2014.10.011.
    Published • 10.1016/j.phytochem.2014.10.011
  32. Heleno, Sandrina A.; Martins, Anabela; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Bioactivity of phenolic acids: Metabolites versus parent compounds: A review". Food Chemistry 173 (2015): 501-513. http://dx.doi.org/10.1016/j.foodchem.2014.10.057.
    Published • 10.1016/j.foodchem.2014.10.057
  33. Bastos, Claudete; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Queiroz, Maria João R.P.; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Chemical characterisation and bioactive properties of Prunus avium L.: The widely studied fruits and the unexplored stems". Food Chemistry 173 (2015): 1045-1053. http://dx.doi.org/10.1016/j.foodchem.2014.10.145.
    Published • 10.1016/j.foodchem.2014.10.145
  34. Pereira, Carla; Barreira, João C. M.; Calhelha, Ricardo C.; Lopes, Melissa; Queiroz, Maria João R. P.; Vilas-Boas, Miguel; Barros, Lillian; Ferreira, Isabel C. F. R.. "Is honey able to potentiate the antioxidant and cytotoxic properties of medicinal plants consumed as infusions for hepatoprotective effects?". Food & Function 6 5 (2015): 1435-1442. http://dx.doi.org/10.1039/c4fo01206b.
    Published • 10.1039/c4fo01206b
  35. Costa, C. N. C.; Hortelão, A. C. L.; Ramos, J. M. F.; Oliveira, A. D. S.; Calhelha, R. C.; Queiroz, Maria-João R. P.; Coutinho, P. J. G.; Castanheira, E. M. S.. Corresponding author: Castanheira, E. M. S.. "A new antitumoral Heteroarylaminothieno[3,2-b]pyridine derivative: its incorporation into liposomes and interaction with proteins monitored by fluorescence". Photochemical Photobiological Sciences 13 12 (2014): 1730-1740. http://dx.doi.org/10.1039/c4pp00287c.
    10.1039/c4pp00287c
  36. Pereira, Carla; Calhelha, Ricardo C.; Antonio, Amilcar L.; Queiroz, Maria-João R. P.; Barros, Lillian; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Effects of gamma radiation on chemical and antioxidant properties, anti-hepatocellular carcinoma activity and hepatotoxicity of borututu". Innovative Food Science & Emerging Technologies 26 (2014): 271-277. http://dx.doi.org/10.1016/j.ifset.2014.05.010.
    10.1016/j.ifset.2014.05.010
  37. Carocho, Márcio; Calhelha, Ricardo C.; Queiroz, Maria-João R.P.; Bento, Albino; Morales, Patricia; Sokovic, Marina; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Infusions and decoctions of Castanea sativa flowers as effective antitumor and antimicrobial matrices". Industrial Crops and Products 62 (2014): 42-46. http://dx.doi.org/10.1016/j.indcrop.2014.08.016.
    Published • 10.1016/j.indcrop.2014.08.016
  38. Rodrigues, A. Rita O.; Carvalho, M. Solange D.; Cardoso, J. André V.; Calhelha, Ricardo C.; Queiroz, Maria-João R.P.; Coutinho, Paulo J.G.; Castanheira, Elisabete M.S.. Corresponding author: Castanheira, Elisabete M.S.. "Benzothienoquinolines: New one-pot synthesis and fluorescence studies of their interaction with DNA and polynucleotides". Journal of Photochemistry and Photobiology A: Chemistry 294 (2014): 20-30. http://dx.doi.org/10.1016/j.jphotochem.2014.08.001.
    Published • 10.1016/j.jphotochem.2014.08.001
  39. Pinto, Eugenia; Neves, Helena; Hrimpeng, Karnjana; Silva, Ana-Filipa; Begouin, Agathe; Lopes, Graciliana; Queiroz, Maria-João R. P.. Corresponding author: Pinto, Eugenia. "Antimicrobial Activity and Mechanism of Action of New N-heteroaryl-1H- (benz)Imidazoles". Mini-Reviews in Medicinal Chemistry 14 11 (2014): 941-952. http://dx.doi.org/10.2174/1389557514666141029225524.
    Published • 10.2174/1389557514666141029225524
  40. Heleno, Sandrina A.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Esteves, Ana P.; Martins, Anabela; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Isabel C.F.R.. "Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synthesized methylated and glucuronate derivatives". Food Research International 55 (2014): 170-175. http://dx.doi.org/10.1016/j.foodres.2013.11.012.
    10.1016/j.foodres.2013.11.012
  41. Pereira, Carla; Calhelha, Ricardo C.; Barros, Lillian; Queiroz, Maria-João R. P.; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Synergisms in antioxidant and anti-hepatocellular carcinoma activities of artichoke, milk thistle and borututu syrups". Industrial Crops and Products 52 (2014): 709-713. http://dx.doi.org/10.1016/j.indcrop.2013.11.050.
    Published • 10.1016/j.indcrop.2013.11.050
  42. Heleno, Sandrina A.; Ferreira, Isabel C. F. R.; Ciric, Ana; Glamoclija, Jasmina; Martins, Anabela; Queiroz, Maria João R. P.; Sokovic, Marina. Corresponding author: Ferreira, Isabel C. F. R.. "Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents". Food Funct. 5 10 (2014): 2521-2528. http://dx.doi.org/10.1039/c4fo00490f.
    Published • 10.1039/c4fo00490f
  43. Calhelha, Ricardo C.; Falcão, Soraia; Queiroz, Maria-João R. P.; Vilas-Boas, Miguel; Ferreira, Isabel C. F. R.. Corresponding author: Ferreira, Isabel C. F. R.. "Cytotoxicity of Portuguese Propolis: The Proximity of the In VitroDoses for Tumor and Normal Cell Lines". BioMed Research International 2014 (2014): 1-7. http://dx.doi.org/10.1155/2014/897361.
    10.1155/2014/897361
  44. Pereira, Carla; Barreira, João C. M.; Calhelha, Ricardo C.; Queiroz, Maria João R. P.; Barros, Lillian; Ferreira, Isabel C. F. R.. Corresponding author: Ferreira, Isabel C. F. R.. "New insights into the effects of formulation type and compositional mixtures on the antioxidant and cytotoxic activities of dietary supplements based-on hepatoprotective plants". Food Funct. 5 9 (2014): 2052-2060. http://dx.doi.org/10.1039/c4fo00387j.
    Published • 10.1039/c4fo00387j
  45. Dias, Maria Inês; Barreira, João C. M.; Calhelha, Ricardo C.; Queiroz, Maria-João R. P.; Oliveira, M. Beatriz P. P.; Sokovic, Marina; Ferreira, Isabel C. F. R.. Corresponding author: Ferreira, Isabel C. F. R.. "Two-Dimensional PCA Highlights the Differentiated Antitumor and Antimicrobial Activity of Methanolic and Aqueous Extracts ofLaurus nobilisL. from Different Origins". BioMed Research International 2014 (2014): 1-10. http://dx.doi.org/10.1155/2014/520464.
    Published • 10.1155/2014/520464
  46. Guimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Carvalho, Ana Maria; Queiroz, Maria-João R. P.; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Characterisation of phenolic compounds in wild fruits from Northeastern Portugal". Food Chemistry 141 4 (2013): 3721-3730. http://dx.doi.org/10.1016/j.foodchem.2013.06.071.
    Published • 10.1016/j.foodchem.2013.06.071
  47. Guimarães, Rafaela; Barros, Lillian; Calhelha, Ricardo C.; Carvalho, Ana Maria; Queiroz, Maria João R. P.; Ferreira, Isabel C. F. R.. "Bioactivity of Different Enriched Phenolic Extracts of Wild Fruits from Northeastern Portugal: A Comparative Study". Plant Foods for Human Nutrition 69 1 (2013): 37-42. http://dx.doi.org/10.1007/s11130-013-0394-5.
    Published • 10.1007/s11130-013-0394-5
  48. Queiroz, Maria-João R.P.; Peixoto, Daniela; Calhelha, Ricardo C.; Soares, Pedro; dos Santos, Tiago; Lima, Raquel T.; Campos, Joana F.; et al. Corresponding author: Queiroz, Maria-João R.P.. "New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death". European Journal of Medicinal Chemistry 69 (2013): 855-862. http://dx.doi.org/10.1016/j.ejmech.2013.09.023.
    Published • 10.1016/j.ejmech.2013.09.023
  49. Heleno, Sandrina A.; Ferreira, Isabel C.F.R.; Esteves, Ana P.; Ciric, Ana; Glamoclija, Jasmina; Martins, Anabela; Sokovic, Marina; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Isabel C.F.R.. "Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters". Food and Chemical Toxicology 58 (2013): 95-100. http://dx.doi.org/10.1016/j.fct.2013.04.025.
    Published • 10.1016/j.fct.2013.04.025
  50. Carvalho, M. Solange D.; Hortelão, Ana C.L.; Calhelha, Ricardo C.; Abreu, Ana S.; Coutinho, Paulo J.G.; Queiroz, Maria-João R.P.; Castanheira, Elisabete M.S.. Corresponding author: Castanheira, Elisabete M.S.. "Fluorescence studies on potential antitumor 6-(hetero)arylthieno[3,2-b]pyridine derivatives in solution and in nanoliposomes". Journal of Photochemistry and Photobiology A: Chemistry 264 (2013): 56-66. http://dx.doi.org/10.1016/j.jphotochem.2013.04.029.
    Published • 10.1016/j.jphotochem.2013.04.029
  51. Begouin, Agathe; Peixoto, Daniela; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Regiocontrolled SNAr Reaction on 2,3-Dihalopyridines with NaSMe To Obtain Bromo(methylthio)pyridines as Key Precursors of 3-Halo-2-(hetero)arylthieno[2,3-b]pyridines and Thieno[3,2-b]pyridines". Synthesis 45 11 (2013): 1489-1496. http://dx.doi.org/10.1055/s-0033-1338442.
    Published • 10.1055/s-0033-1338442
  52. Begouin, Agathe; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Scope and Limitations of the Base-Free Copper(I) Oxide CatalyzedN-Heteroarylation of 1H-(Benz)imidazoles withB-Heteroarylboronic Acids or 2-Heteroaryl-4,4,5,5-tetramethyl-1,3,2-dioxaborolanes". Helvetica Chimica Acta 96 5 (2013): 853-863. http://dx.doi.org/10.1002/hlca.201200310.
    Published • 10.1002/hlca.201200310
  53. Heleno, Sandrina A.; Stojkovic, Dejan; Barros, Lillian; Glamoclija, Jasmina; Sokovic, Marina; Martins, Anabela; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.. "A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia". Food Research International 51 1 (2013): 236-243. http://dx.doi.org/10.1016/j.foodres.2012.12.020.
    Published • 10.1016/j.foodres.2012.12.020
  54. Calhelha, Ricardo C.; Peixoto, Daniela; Vilas Boas, Miguel; Queiroz, Maria-João R. P.; Ferreira, Isabel C. F. R.. "Antioxidant activity of aminodiarylamines in the thieno[3,2-b]pyridine series: radical scavenging activity, lipid peroxidation inhibition and redox profile". Journal of Enzyme Inhibition and Medicinal Chemistry 29 3 (2013): 311-316. http://dx.doi.org/10.3109/14756366.2013.777718.
    Published • 10.3109/14756366.2013.777718
  55. Queiroz, Maria-João R. P.; Peixoto, Daniela; Rodrigues, Ana Rita O.; Mendes, Pedro M.F.; Costa, Cátia N.C.; Coutinho, Paulo J.G.; Castanheira, Elisabete M.S.. Corresponding author: Queiroz, Maria-João R. P.. "New 1,3-diarylureas linked by CC Suzuki coupling to the methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate moiety: Synthesis and fluorescence studies in solution and in lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 255 (2013): 27-35. http://dx.doi.org/10.1016/j.jphotochem.2013.01.006.
    Published • 10.1016/j.jphotochem.2013.01.006
  56. Guimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Carvalho, Ana Maria; Santos-Buelga, Celestino; Queiroz, Maria-João R. P.; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Infusion and decoction of wild German chamomile: Bioactivity and characterization of organic acids and phenolic compounds". Food Chemistry 136 2 (2013): 947-954. http://dx.doi.org/10.1016/j.foodchem.2012.09.007.
    Published • 10.1016/j.foodchem.2012.09.007
  57. Guimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Carvalho, Ana Maria; Santos-Buelga, Celestino; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.. "Nutrients, phytochemicals and bioactivity of wild Roman chamomile: A comparison between the herb and its preparations". Food Chemistry 136 2 (2013): 718-725. http://dx.doi.org/10.1016/j.foodchem.2012.08.025.
    Published • 10.1016/j.foodchem.2012.08.025
  58. Soares, Pedro; Costa, Raquel; Froufe, Hugo J. C.; Calhelha, Ricardo C.; Peixoto, Daniela; Ferreira, Isabel C. F. R.; Abreu, Rui M. V.; Soares, Raquel; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling Studies". BioMed Research International 2013 (2013): 1-9. http://dx.doi.org/10.1155/2013/154856.
    Published • 10.1155/2013/154856
  59. Peixoto, Daniela; Begouin, Agathe; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridines from 2,3-dihalopyridines, (hetero)arylalkynes, and Na2S. Further functionalizations". Tetrahedron 68 35 (2012): 7082-7094. http://dx.doi.org/10.1016/j.tet.2012.06.057.
    Published • 10.1016/j.tet.2012.06.057
  60. Abreu, Ana S.; Castanheira, Elisabete M.S.; Coutinho, Paulo J.G.; Queiroz, Maria-João R.P.; Ferreira, Paula M.T.; Vale-Silva, Luís A.; Pinto, Eugénia. Corresponding author: Queiroz, Maria-João R.P.. "Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 240 (2012): 14-25. http://dx.doi.org/10.1016/j.jphotochem.2012.05.009.
    Published • 10.1016/j.jphotochem.2012.05.009
  61. Queiroz, Maria-João R. P.; Dias, Sofia; Peixoto, Daniela; Rodrigues, Ana Rita O.; Oliveira, Andreia D.S.; Coutinho, Paulo J.G.; Vale-Silva, Luís A.; Pinto, Eugénia; Castanheira, Elisabete M.S.. Corresponding author: Queiroz, Maria-João R. P.. "New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series: Synthesis and fluorescence studies in solution and in nanoliposomes". Journal of Photochemistry and Photobiology A: Chemistry 238 (2012): 71-80. http://dx.doi.org/10.1016/j.jphotochem.2012.04.007.
    Published • 10.1016/j.jphotochem.2012.04.007
  62. Heleno, Sandrina A.; Barros, Lillian; Martins, Anabela; Queiroz, Maria João R. P.; Santos-Buelga, Celestino; Ferreira, Isabel C. F. R.. Corresponding author: Ferreira, Isabel C. F. R.. "Phenolic, Polysaccharidic, and Lipidic Fractions of Mushrooms from Northeastern Portugal: Chemical Compounds with Antioxidant Properties". Journal of Agricultural and Food Chemistry 60 18 (2012): 4634-4640. http://dx.doi.org/10.1021/jf300739m.
    Published • 10.1021/jf300739m
  63. Heleno, Sandrina A.; Barros, Lillian; Martins, Anabela; Queiroz, Maria-João R. P.; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.. Corresponding author: Ferreira, Isabel C.F.R.. "Fruiting body, spores and in vitro produced mycelium of Ganoderma lucidum from Northeast Portugal: A comparative study of the antioxidant potential of phenolic and polysaccharidic extracts". Food Research International 46 1 (2012): 135-140. http://dx.doi.org/10.1016/j.foodres.2011.12.009.
    Published • 10.1016/j.foodres.2011.12.009
  64. Calhelha, Ricardo C.; Ferreira, Isabel C. F. R.; Peixoto, Daniela; Abreu, Rui M. V.; Vale-Silva, Luís A.; Pinto, Eugénia; Lima, Raquel T.; et al. Corresponding author: Queiroz, Maria-João R. P.. "Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells". Molecules 17 4 (2012): 3834-3843. http://dx.doi.org/10.3390/molecules17043834.
    Published • 10.3390/molecules17043834
  65. Abreu, Rui M. V.; Froufe, Hugo J. C.; Queiroz, Maria-João R. P.; Ferreira, Isabel C. F. R.. Corresponding author: Abreu, Rui M. V.. "Selective Flexibility of Side-Chain Residues Improves VEGFR-2 Docking Score using AutoDock Vina". Chemical Biology & Drug Design 79 4 (2012): 530-534. http://dx.doi.org/10.1111/j.1747-0285.2011.01313.x.
    Published • 10.1111/j.1747-0285.2011.01313.x
  66. Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Lima, Raquel T.; Vasconcelos, M. Helena; Adega, Filomena; Chaves, Raquel; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies". European Journal of Medicinal Chemistry 46 12 (2011): 5800-5806. http://dx.doi.org/10.1016/j.ejmech.2011.09.029.
    Published • 10.1016/j.ejmech.2011.09.029
  67. Begouin, Agathe; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Tandem Palladium/Charcoal-Copper(I) Iodide (Pd/C-CuI) Catalyzed Sonogashira Coupling and Intramolecular Cyclization from 2-Bromonicotinic Acid (=2-Bromopyridine-3-carboxylic Acid) and Ethynylarenes to 4-Azaphthalides (=Furo[3,4-b]pyridin-5(7H)-ones) and 5". Helvetica Chimica Acta 94 10 (2011): 1792-1801. http://dx.doi.org/10.1002/hlca.201100060.
    Published • 10.1002/hlca.201100060
  68. Abreu, R.M.V.; Froufe, H.J.C.; Daniel, P.O.M.; Queiroz, M.J.R.P.; Ferreira, I.C.F.R.. "ChemT, an open-source software for building template-based chemical libraries". SAR and QSAR in Environmental Research 22 5-6 (2011): 603-610. http://dx.doi.org/10.1080/1062936x.2011.604097.
    10.1080/1062936x.2011.604097
  69. Hermenegildo, Bruno F.; Pereira, Goreti; Abreu, Ana S.; Castanheira, Elisabete M.S.; Ferreira, Paula M.T.; Queiroz, Maria-João R. P.. Corresponding author: Castanheira, Elisabete M.S.. "Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 221 1 (2011): 47-57. http://dx.doi.org/10.1016/j.jphotochem.2011.04.022.
    Published • 10.1016/j.jphotochem.2011.04.022
  70. Queiroz, Maria-João R. P.; Calhelha, Ricardo C.; Vale-Silva, Luís A.; Pinto, Eugénia; Almeida, Gabriela M.; Vasconcelos, M. Helena. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure–activity relationships, effects on the cell cycle and apoptosis". European Journal of Medicinal Chemistry 46 1 (2011): 236-240. http://dx.doi.org/10.1016/j.ejmech.2010.11.009.
    Published • 10.1016/j.ejmech.2010.11.009
  71. Castanheira, E.M.S.; Carvalho, M.S.D.; Rodrigues, A.R.O.; Calhelha, R.C.; Queiroz, M.-J.R.P.. Corresponding author: Castanheira, E.M.S.. "New potential antitumoral fluorescent tetracyclic thieno[3,2-b]pyridine derivatives: Interaction with DNA and nanosized liposomes". Nanoscale Research Letters 6 (2011): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856035671&partnerID=MN8TOARS.
    Published • 10.1186/1556-276X-6-379
  72. Abreu, A.S.; Castanheira, E.M.S.; Queiroz, M.-J.R.P.; Ferreira, P.M.T.; Vale-Silva, L.A.; Pinto, E.. "Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate". Nanoscale Research Letters 6 (2011): 1-6. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856065265&partnerID=MN8TOARS.
    Published • 10.1186/1556-276X-6-482
  73. Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Abreu, R. M. V.; Raquel T. Lima; Silva, L. A. V.; Pinto, E.; Alvelos, M. Inês; Vasconcelos, M. Helena; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of aminodiarylamines in the thieno[3,2-b]piridine series and effects on tumour cell growth inhibition, cell cycle and apoptosis". Revista Portuguesa de Farmácia LII 6 Suplem (2011): 77-78.
    Published
  74. Queiroz, Maria-João R. P.; Calhelha, Ricardo C.; Vale-Silva, Luís A.; Pinto, Eugénia; Lima, Raquel T.; Vasconcelos, M. Helena. Corresponding author: Queiroz, Maria-João R. P.. "Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle". European Journal of Medicinal Chemistry 45 12 (2010): 5628-5634. http://dx.doi.org/10.1016/j.ejmech.2010.09.014.
    Published • 10.1016/j.ejmech.2010.09.014
  75. Queiroz, Maria-João R. P.; Calhelha, Ricardo C.; Vale-Silva, Luís A.; Pinto, Eugénia; São-José Nascimento, M.. Corresponding author: Queiroz, Maria-João R. P.. "Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: Synthesis and antitumoral activities". European Journal of Medicinal Chemistry 45 12 (2010): 5732-5738. http://dx.doi.org/10.1016/j.ejmech.2010.09.030.
    Published • 10.1016/j.ejmech.2010.09.030
  76. Abreu, Rui MV; Froufe, Hugo JC; Queiroz, Maria João RP; Ferreira, Isabel CFR. Corresponding author: Abreu, Rui MV. "MOLA: a bootable, self-configuring system for virtual screening using AutoDock4/Vina on computer clusters". Journal of Cheminformatics 2 1 (2010): http://dx.doi.org/10.1186/1758-2946-2-10.
    Published • 10.1186/1758-2946-2-10
  77. Castanheira, Elisabete M. S.; Carvalho, M. Solange D.; Soares, Daniel J. G.; Coutinho, Paulo J. G.; Calhelha, Ricardo C.; Queiroz, Maria-João R. P.. Corresponding author: Castanheira, Elisabete M. S.. "Fluorescence Studies on New Potential Antitumoral Benzothienopyran-1-ones in Solution and in Liposomes". Journal of Fluorescence 21 3 (2010): 911-922. http://dx.doi.org/10.1007/s10895-010-0607-3.
    Published • 10.1007/s10895-010-0607-3
  78. Pereira, Goreti; Castanheira, Elisabete M. S.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.. Corresponding author: Castanheira, Elisabete M. S.. "Synthesis and Photophysical Studies of New Fluorescent Indole Derivatives Obtained from beta-bromodehydroamino Acids. Interaction with Fluoride Anions". European Journal of Organic Chemistry 2010 3 (2010): 464-475. http://doi.org/10.1002/ejoc.200900737.
    Published • 10.1002/ejoc.200900737
  79. Calhelha, Ricardo C.; Queiroz, Maria-João R.P.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of new thieno[3,2-b]pyridine derivatives by palladium-catalyzed couplings and intramolecular cyclizations". Tetrahedron Letters 51 2 (2010): 281-283. http://dx.doi.org/10.1016/j.tetlet.2009.10.138.
    Published • 10.1016/j.tetlet.2009.10.138
  80. Silva, J. P.; Machado, V. A.; Calhelha, R. C.; Queiroz, Maria-João R. P.; coutinho, O. P.. "Di(hetero)arylamines in the benzo[b]thiophene series as novel potent antioxidants.". Drug Discoveries & Therapeutics 4 4 (2010): 246-256.
    Published
  81. Castanheira, E.M.S.; Abreu, A.S.; Queiroz, M.J.R.P.; Ferreira, P.M.T.. "Studies of encapsulation of a new potential antitumoral indole derivative in nanoliposomes for drug delivery applications". European Cells and Materials 20 SUPPL.3 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-84860903846&partnerID=MN8TOARS.
    Published
  82. Castanheira, Elisabete M.S.; Abreu, Ana S.; Queiroz, Maria-João R.P.; Ferreira, Paula M.T.; Coutinho, Paulo J.G.; Nazareth, Nair; Nascimento, M. São-José. Corresponding author: Castanheira, Elisabete M.S.. "Fluorescence properties of a potential antitumoral benzothieno[3,2-b]pyrrole in solution and lipid membranes". Journal of Photochemistry and Photobiology A: Chemistry 206 2-3 (2009): 220-226. http://dx.doi.org/10.1016/j.jphotochem.2009.07.007.
    Published • 10.1016/j.jphotochem.2009.07.007
  83. Pereira, Goreti; Abreu, Ana S.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.. Corresponding author: Castanheira, Elisabete M. S.. "Synthesis and Photophysical Studies of a Pyrenylindole and a Phenalenoindole Obtained from Dehydroamino Acid Derivatives - Application as Fluorescent Probes for Biological Systems". European Journal of Organic Chemistry 2009 23 (2009): 3906-3916. http://dx.doi.org/10.1002/ejoc.200900351.
    Published • 10.1002/ejoc.200900351
  84. Begouin, Agathe; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Palladium-Catalysed Multicomponent Aminocarbonylation of Aryl or Heteroaryl Halides with [Mo(CO)6] and Aryl- or ­Heteroarylamines Using Conventional Heating". European Journal of Organic Chemistry 2009 17 (2009): 2820-2827. http://dx.doi.org/10.1002/ejoc.200900167.
    Published • 10.1002/ejoc.200900167
  85. Abreu, Rui M.V.; Ferreira, Isabel C.F.R.; Queiroz, Maria João R.P.. Corresponding author: Ferreira, Isabel C.F.R.. "QSAR model for predicting radical scavenging activity of di(hetero)arylamines derivatives of benzo[b]thiophenes". European Journal of Medicinal Chemistry 44 5 (2009): 1952-1958. http://dx.doi.org/10.1016/j.ejmech.2008.11.011.
    Published • 10.1016/j.ejmech.2008.11.011
  86. Queiroz, Maria-João R.P.; Calhelha, Ricardo C.; Vale-Silva, Luís A.; Pinto, Eugénia; São-José Nascimento, M.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of novel 3-(aryl)benzothieno[2,3-c]pyran-1-ones from Sonogashira products and intramolecular cyclization: Antitumoral activity evaluation". European Journal of Medicinal Chemistry 44 5 (2009): 1893-1899. http://dx.doi.org/10.1016/j.ejmech.2008.11.002.
    Published • 10.1016/j.ejmech.2008.11.002
  87. Abreu, Rui; Falcão, Soraia; Calhelha, Ricardo C.; Ferreira, Isabel C.F.R.; Queiroz, Maria-João R.P.; Vilas-Boas, Miguel. Corresponding author: Ferreira, Isabel C.F.R.. "Insights in the antioxidant activity of diarylamines from the 2,3-dimethylbenzo[b]thiophene through the redox profile". Journal of Electroanalytical Chemistry 628 1-2 (2009): 43-47. http://dx.doi.org/10.1016/j.jelechem.2009.01.004.
    Published • 10.1016/j.jelechem.2009.01.004
  88. Pinto-Basto, Diana; Silva, João P.; Queiroz, Maria-João R.P.; Moreno, António J.; Coutinho, Olga P.. Corresponding author: Coutinho, Olga P.. "Antioxidant activity of synthetic diarylamines: A mitochondrial and cellular approach". Mitochondrion 9 1 (2009): 17-26. http://dx.doi.org/10.1016/j.mito.2008.10.001.
    Published • 10.1016/j.mito.2008.10.001
  89. Abreu, Ana S.; Castanheira, Elisabete M. S.; Ferreira, Paula M. T.; Monteiro, Luís S.; Pereira, Goreti; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula M. T.. "Pyrenylamino Acids: Synthesis, Photophysical and Electrochemical Studies". European Journal of Organic Chemistry 2008 34 (2008): 5697-5703. http://dx.doi.org/10.1002/ejoc.200800640.
    Published • 10.1002/ejoc.200800640
  90. Castanheira, Elisabete M. S.; Abreu, Ana S.; Carvalho, M. Solange D.; Queiroz, Maria-João R. P.; Ferreira, Paula M. T.. Corresponding author: Castanheira, Elisabete M. S.. "Fluorescence Studies on Potential Antitumoral Heteroaryl and Heteroannulated Indoles in Solution and in Lipid Membranes". Journal of Fluorescence 19 3 (2008): 501-509. http://dx.doi.org/10.1007/s10895-008-0439-6.
    Published • 10.1007/s10895-008-0439-6
  91. Queiroz, Maria-João R.P.; Begouin, Agathe; Pereira, Goreti; Ferreira, Paula M.T.. Corresponding author: Queiroz, Maria-João R.P.. "New synthesis of methyl 5-aryl or heteroaryl pyrrole-2-carboxylates by a tandem Sonogashira coupling/5-endo-dig-cyclization from ß-iododehydroamino acid methyl esters and terminal alkynes". Tetrahedron 64 47 (2008): 10714-10720. http://dx.doi.org/10.1016/j.tet.2008.08.105.
    Published • 10.1016/j.tet.2008.08.105
  92. Pinto, Eugénia; Queiroz, Maria-João R.P.; Vale-Silva, Luís A.; Oliveira, João F.; Begouin, Agathe; Begouin, Jeanne-Marie; Kirsch, Gilbert. Corresponding author: Pinto, Eugénia. "Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety". Bioorganic & Medicinal Chemistry 16 17 (2008): 8172-8177. http://dx.doi.org/10.1016/j.bmc.2008.07.042.
    Published • 10.1016/j.bmc.2008.07.042
  93. Queiroz, Maria João R.P.; Abreu, Ana S.; Calhelha, Ricardo C.; Carvalho, M. Solange D.; Ferreira, Paula M.T.. Corresponding author: Queiroz, Maria João R.P.. "New strategies for the synthesis of heteroannulated 2-pyridinones, substituted 2-quinolinones and coumarins from dehydroamino acid derivatives". Tetrahedron 64 22 (2008): 5139-5146. http://dx.doi.org/10.1016/j.tet.2008.03.057.
    Published • 10.1016/j.tet.2008.03.057
  94. Queiroz, Maria-João R.P.; Abreu, Ana S.; Carvalho, M. Solange D.; Ferreira, Paula M.T.; Nazareth, Nair; São-José Nascimento, M.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation". Bioorganic & Medicinal Chemistry 16 10 (2008): 5584-5589. http://dx.doi.org/10.1016/j.bmc.2008.04.004.
    Published • 10.1016/j.bmc.2008.04.004
  95. Ferreira, P. M. T.; Monteiro, L. S.; Queiroz, M.-J. R. P.; Pereira, G.. Corresponding author: Ferreira, P. M. T.. "Synthesis of bis-amino acid derivatives by Suzuki cross-coupling, Michael addition and substitution reactions". Amino Acids 36 3 (2008): 429-436. http://dx.doi.org/10.1007/s00726-008-0095-9.
    Published • 10.1007/s00726-008-0095-9
  96. Queiroz, Maria-João R.P.; Castanheira, Elisabete M.S.; Carvalho, M. Solange D.; Abreu, Ana S.; Ferreira, Paula M.T.; Karadeniz, Hakan; Erdem, Arzum. Corresponding author: Queiroz, Maria-João R.P.. "New tetracyclic heteroaromatic compounds based on dehydroamino acids: photophysical and electrochemical studies of interaction with DNA". Tetrahedron 64 2 (2008): 382-391. http://dx.doi.org/10.1016/j.tet.2007.10.090.
    Published • 10.1016/j.tet.2007.10.090
  97. Queiroz, Maria-João R.P.; Calhelha, Ricardo C.; Kirsch, Gilbert. Corresponding author: Queiroz, Maria-João R.P.. "Reactivity of several deactivated 3-aminobenzo[b]thiophenes in the Buchwald-Hartwig C-N coupling. Scope and limitations". Tetrahedron 63 52 (2007): 13000-13005. http://dx.doi.org/10.1016/j.tet.2007.10.029.
    Published • 10.1016/j.tet.2007.10.029
  98. Queiroz, Maria-João R. P.; Castanheira, Elisabete M.S.; Lopes, Teresa C.T.; Cruz, Yvonne K.; Kirsch, Gilbert. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of fluorescent tetracyclic lactams by a one pot three steps palladium-catalyzed borylation, Suzuki coupling (BSC) and lactamization". Journal of Photochemistry and Photobiology A: Chemistry 190 1 (2007): 45-52. http://dx.doi.org/10.1016/j.jphotochem.2007.03.011.
    Published • 10.1016/j.jphotochem.2007.03.011
  99. Begouin, Agathe; Hesse, Stéphanie; Queiroz, Maria-João R. P.; Kirsch, Gilbert. Corresponding author: Kirsch, Gilbert. "Palladium-Catalyzed Buchwald-Hartwig Coupling of Deactivated Aminothiophenes with Substituted Halopyridines". European Journal of Organic Chemistry 2007 10 (2007): 1678-1682. http://dx.doi.org/10.1002/ejoc.200600951.
    Published • 10.1002/ejoc.200600951
  100. Queiroz, Maria-João R.P.; Abreu, Ana S.; Castanheira, Elisabete M.S.; Ferreira, Paula M.T.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis of new 3-arylindole-2-carboxylates using ß,ß-diaryldehydroamino acids as building blocks. Fluorescence studies". Tetrahedron 63 10 (2007): 2215-2222. http://dx.doi.org/10.1016/j.tet.2006.12.084.
    Published • 10.1016/j.tet.2006.12.084
  101. Queiroz, Maria-João R.P.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald-Hartwig C-N cross-coupling". Bioorganic & Medicinal Chemistry 15 4 (2007): 1788-1794. http://dx.doi.org/10.1016/j.bmc.2006.11.035.
    Published • 10.1016/j.bmc.2006.11.035
  102. Queiroz, Maria-João R.P.; Ferreira, Isabel C.F.R.; Gaetano, Yannick De; Kirsch, Gilbert; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Queiroz, Maria-João R.P.. "Synthesis and antimicrobial activity studies of ortho-chlorodiarylamines and heteroaromatic tetracyclic systems in the benzo[b]thiophene series". Bioorganic & Medicinal Chemistry 14 20 (2006): 6827-6831. http://dx.doi.org/10.1016/j.bmc.2006.06.035.
    Published • 10.1016/j.bmc.2006.06.035
  103. Begouin, Agathe; Hesse, Stéphanie; Queiroz, Maria-João; Kirsch, Gilbert. Corresponding author: Kirsch, Gilbert. "Reactivity of Substituted Bromothiophenecarboxylates in Palladium-Catalyzed N-Arylation of Hetarylamines". Synthesis 2006 16 (2006): 2794-2798. http://dx.doi.org/10.1055/s-2006-942510.
    Published • 10.1055/s-2006-942510
  104. Queiroz, Maria-João R. P.; Castanheira, Elisabete M.S.; Pinto, Ana M.R.; Ferreira, Isabel C.F.R.; Begouin, Agathe; Kirsch, Gilbert. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of the first thieno-delta-carboline. Fluorescence studies in solution and in lipid vesicles". Journal of Photochemistry and Photobiology A: Chemistry 181 2-3 (2006): 290-296. http://dx.doi.org/10.1016/j.jphotochem.2005.12.010.
    10.1016/j.jphotochem.2005.12.010
  105. Ferreira, Isabel C.F.R.; Queiroz, Maria-João R.P.; Vilas-Boas, Miguel; Estevinho, Leti´cia M.; Begouin, Agathe; Kirsch, Gilbert. Corresponding author: Ferreira, Isabel C.F.R.. "Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power". Bioorganic & Medicinal Chemistry Letters 16 5 (2006): 1384-1387. http://dx.doi.org/10.1016/j.bmcl.2005.11.035.
    10.1016/j.bmcl.2005.11.035
  106. Castanheira, Elisabete M. S.; Pinto, Ana M. R.; Queiroz, Maria-João R. P.. "Fluorescence of a Benzothienopyridopyrimidone in Solution and in Lipid Vesicles". Journal of Fluorescence 16 2 (2006): 251-257. http://dx.doi.org/10.1007/s10895-005-0050-z.
    10.1007/s10895-005-0050-z
  107. Viola, Giampietro; Salvador, Alessia; Vedaldi, Daniela; Fortunato, Elena; Disarò, Silvia; Basso, Giuseppe; Queiroz, Maria-João R.P.. "Induction of apoptosis by photoexcited tetracyclic compounds derivatives of benzo[b]thiophenes and pyridines". Journal of Photochemistry and Photobiology B: Biology 82 2 (2006): 105-116. http://dx.doi.org/10.1016/j.jphotobiol.2005.09.004.
    10.1016/j.jphotobiol.2005.09.004
  108. Queiroz, Maria-João R. P.; Abreu, Ana S.; Ferreira, Paula M. T.; Oliveira, M. Manuel; Dubest, Roger; Aubard, Jean; Samat, André. "A Thieno-2H-chromene a-Amino Acid Derivative:¿ Synthesis and Photochromic Properties". Organic Letters 7 22 (2005): 4811-4814. http://dx.doi.org/10.1021/ol051378a.
    10.1021/ol051378a
  109. Abreu, Ana S.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.; Ferreira, Isabel C. F. R.; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of ß-Benzo[b]thienyldehydrophenylalanine Derivatives by One-Pot Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted Intramolecular Cyclization - Studies of Fluorescence and Antimicrobial Activity". European Journal of Organic Chemistry 2005 14 (2005): 2951-2957. http://dx.doi.org/10.1002/ejoc.200500040.
    10.1002/ejoc.200500040
  110. Venanzi, Mariano; Bocchinfuso, Gianfranco; Palleschi, Antonio; Abreu, Ana S.; Ferreira, Paula M.T.; Queiroz, Maria-João R.P.. "New fluorescent benzo[b]thienyl amino acid derivatives based on sulfanylphenyl benzo[b]thiophenes". Journal of Photochemistry and Photobiology A: Chemistry 170 2 (2005): 181-188. http://dx.doi.org/10.1016/j.jphotochem.2004.08.011.
    10.1016/j.jphotochem.2004.08.011
  111. Begouin, Agathe; Hesse, Stéphanie; Queiroz, Maria-João R.; Kirsch, Gilbert. Corresponding author: Kirsch, Gilbert. "Synthesis of Diarylamines in the Thiophene Series by Buchwald-Hartwig Coupling­". Synthesis 14 (2005): 2373-2378. http://dx.doi.org/10.1055/s-2005-870014.
    Published • 10.1055/s-2005-870014
  112. Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Letícia M.; Queiroz, Maria-João R.P.. Corresponding author: Ferreira, Isabel C.F.R.. "Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study". Bioorganic & Medicinal Chemistry Letters 14 23 (2004): 5831-5833. http://dx.doi.org/10.1016/j.bmcl.2004.09.038.
    Published • 10.1016/j.bmcl.2004.09.038
  113. Abreu, Ana S.; Ferreira, Paula M.T.; Monteiro, Luís S.; Queiroz, Maria-João R.P.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Letícia M.. Corresponding author: Ferreira, Paula M.T.. "Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity". Tetrahedron 60 51 (2004): 11821-11828. http://dx.doi.org/10.1016/j.tet.2004.09.107.
    Published • 10.1016/j.tet.2004.09.107
  114. Abreu, Ana S.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.; Gatto, Emanuela; Venanzi, Mariano. Corresponding author: Queiroz, Maria-João R. P.. "Sonogashira Cross-Couplings of Dehydroamino Acid Derivatives and Phenylacetylenes". European Journal of Organic Chemistry 2004 19 (2004): 3985-3991. http://dx.doi.org/10.1002/ejoc.200400145.
    Published • 10.1002/ejoc.200400145
  115. Queiroz, Maria-João R. P.; Begouin, Agathe; Ferreira, Isabel C. F. R.; Kirsch, Gilbert; Calhelha, Ricardo C.; Barbosa, Sandra; Estevinho, Letícia M.. Corresponding author: Queiroz, Maria-João R. P.. "Palladium-Catalysed Amination of Electron-Deficient or Relatively Electron-Rich Benzo[b]thienyl Bromides- Preliminary Studies of Antimicrobial Activity and SARs". European Journal of Organic Chemistry 2004 17 (2004): 3679-3685. http://dx.doi.org/10.1002/ejoc.200400218.
    10.1002/ejoc.200400218
  116. Abreu, Ana S.; Silva, Natália O.; Ferreira, Paula M. T.; Queiroz, Maria-João R. P.. Corresponding author: Ferreira, Paula M. T.. "Synthesis of Novel Amino Acids and Dehydroamino Acids Containing the Benzo[b]thiophene Moiety". European Journal of Organic Chemistry 2003 8 (2003): 1537-1544. http://dx.doi.org/10.1002/ejoc.200390212.
    Published • 10.1002/ejoc.200390212
  117. Seixas de Melo, J.; Rodrigues, L. M.; Serpa, C.; Arnaut, L. G.; Ferreira, I. C. F. R.; Queiroz, M.-J. R. P.. Corresponding author: Seixas de Melo, J.. "Photochemistry and Photophysics of Thienocarbazoles". Photochemistry and Photobiology 77 2 (2003): 121-128. http://dx.doi.org/10.1562/0031-8655(2003)0770121papot2.0.co2.
    Published • 10.1562/0031-8655(2003)0770121papot2.0.co2
  118. Abreu, A.S.; Silva, N.O.; Ferreira, P.M.T.; Queiroz, Maria-João R. P.; Venanzi, M.. Corresponding author: Ferreira, P.M.T.. "New ß,ß-Bis(benzo[b]thienyl)dehydroalanine Derivatives: Synthesis and Cyclization". European Journal of Organic Chemistry 2003 24 (2003): 4792-4796. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347362651&partnerID=MN8TOARS.
    Published • 10.1002/ejoc.200300394
  119. Abreu, A.S.; Silva, N.O.; Ferreira, P.M.T.; Queiroz, M.-J.R.P.. "Synthesis of novel amino acids and dehydroamino acids containing the benzo[b]thiophene moiety". European Journal of Organic Chemistry 8 (2003): 1537-1544. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038222580&partnerID=MN8TOARS.
  120. Ferreira, I.C.F.R.; Queiroz, M.-J.R.P.; Kirsch, G.. "Tandem palladium-catalyzed borylation and Suzuki coupling (BSC) to thienocarbazole precursors". Tetrahedron Letters 44 23 (2003): 4327-4329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037877929&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)00952-3
  121. Ferreira, I.C.F.R.; Queiroz, M.-J.R.P.; Kirsch, G.. Corresponding author: Queiroz, M.-J.R.P.. "Palladium-catalyzed amination and cyclization to heteroannellated indoles and carbazoles". Tetrahedron 59 21 (2003): 3737-3743. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037723821&partnerID=MN8TOARS.
    Published • 10.1016/S0040-4020(03)00552-0
  122. Martins, M.A.M.; Lima, N.; Silvestre, A.J.D.; Queiroz, M.J.. Corresponding author: Queiroz, M.J.. "Comparative studies of fungal degradation of single or mixed bioaccessible reactive azo dyes". Chemosphere 52 6 (2003): 967-973. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038133407&partnerID=MN8TOARS.
    Published • 10.1016/S0045-6535(03)00286-8
  123. Ferreira, I.C.F.R.; Queiroz, M.-J.R.P.; Kirsch, G.. "Synthesis of diarylamines in the benzo[b]thiophene series bearing electron donating or withdrawing groups by Buchwald-Hartwig C-N coupling". Tetrahedron 59 7 (2003): 975-981. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037429029&partnerID=MN8TOARS.
    10.1016/S0040-4020(02)01656-3
  124. Queiroz, M.-J.R.P.; Plasencia, P.M.S.; Dubest, R.; Aubard, J.; Guglielmetti, R.. "Synthesis and photochromic behaviour of new methyl induced linear and angular thieno-2H-chromenes". Tetrahedron 59 14 (2003): 2567-2573. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037474657&partnerID=MN8TOARS.
    10.1016/S0040-4020(03)00262-X
  125. Abreu, A.S.; Silva, N.O.; Ferreira, P.M.T.; Queiroz, M.-J.R.P.. "Synthesis and intramolecular cyclization of novel ß,ß-bis-(benzo[b]thienyl)dehydroalanine derivatives". Tetrahedron Letters 44 16 (2003): 3377-3379. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037436909&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)00564-1
  126. Abreu, A.S.; Silva, N.O.; Ferreira, P.M.T.; Queiroz, M.-J.R.P.. "Palladium-catalyzed borylation and Suzuki coupling (BSC) to obtain ß-substituted dehydroamino acid derivatives". Tetrahedron Letters 44 32 (2003): 6007-6009. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037629717&partnerID=MN8TOARS.
    10.1016/S0040-4039(03)01473-4
  127. Silva, Natália O.; Abreu, Ana S.; Ferreira, Paula M. T.; Monteiro, Luís S.; Queiroz, Maria-João R. P.. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis Using Suzuki Cross Couplings of Sulfur Analogues of Dehydrotryptophan with a Definite Stereochemistry". European Journal of Organic Chemistry 2002 15 (2002): 2524. http://dx.doi.org/10.1002/1099-0690(200208)2002:15<2524::aid-ejoc2524>3.0.co;2-w.
    10.1002/1099-0690(200208)2002:15<2524::aid-ejoc2524>3.0.co;2-w
  128. Macedo, A.; Queiroz, M.J.T.. "Cardiovascular risk factors - From mathematics to clinical practice,Factores de risco cardiovascular - Da fórmula matemática à prática clínica". Acta Medica Portuguesa 15 4 (2002): 277-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842857679&partnerID=MN8TOARS.
  129. Martins, M.A.M.; Queiroz, M.J.; Silvestre, A.J.D.; Lima, N.; Martins, M.Adosinda M.; Queiroz, M.João; Silvestre, Armando J.D.; Lima, Nelson. "Relationship of chemical structures of textile dyes on the pre-adaptation medium and the potentialities of their biodegradation by Phanerochaete chrysosporium". Research in Microbiology 153 6 (2002): 361-368. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036337664&partnerID=MN8TOARS.
    10.1016/S0923-2508(02)01332-3
  130. Silva, N.O.; Abreu, A.S.; Ferreira, P.M.T.; Monteiro, L.S.; Queiroz, M.-J.R.P.. "Synthesis using Suzuki cross couplings of sulfur analogues of dehydrotryptophan with a definite stereochemistry". European Journal of Organic Chemistry 15 (2002): 2524-2528. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036326486&partnerID=MN8TOARS.
  131. Ferreira, I.C.F.R.; Queiroz, M.-J.R.P.; Kirsch, G.. "Novel synthetic routes to thienocarbazoles via palladium or copper catalyzed amination or amidation of arylhalides and intramolecular cyclization". Tetrahedron 58 39 (2002): 7943-7949. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037163272&partnerID=MN8TOARS.
    10.1016/S0040-4020(02)00904-3
  132. Martins, M.Adosinda M.; Ferreira, Isabel C.; Santos, Isabel M.; Queiroz, M.João; Lima, Nelson; Martins, M.AdosindaM.; Ferreira, I.C.; Santos, I.M.; Lima, N.. "Biodegradation of bioaccessible textile azo dyes by Phanerochaete chrysosporium". Journal of Biotechnology 89 2-3 (2001): 91-98. http://dx.doi.org/10.1016/s0168-1656(01)00318-2.
    10.1016/s0168-1656(01)00318-2
  133. Ferreira, C. F. R.; Queiroz, Maria-João R. P.; Kirsch, Gilbert. "Synthesis of new methylated thieno[2,3-a] and [3,2-b]carbazoles by reductive cyclization of 6-(2'-Nitrophenyl)benzo[b]thiophenes obtained by palladium-catalyzed cross-coupling isabel". Journal of Heterocyclic Chemistry 38 3 (2001): 749-754. http://dx.doi.org/10.1002/jhet.5570380334.
    10.1002/jhet.5570380334
  134. Queiroz, Maria-João R. P.; Dubest, Roger; Aubard, Jean; Faure, R; Guglielmetti, Robert. Corresponding author: Queiroz, Maria-João R. P.. "Synthesis of photochromic thieno-2H-chromene derivatives". Dyes and Pigments 47 3 (2000): 219-229. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034507436&partnerID=MN8TOARS.
    10.1016/S0143-7208(00)00083-8
  135. Herz, Hans-Georg; Queiroz, M.J.R.P.. "2-Arylvinylation of 1-Methylindole by Palladium-Catalyzed Cross-Coupling Reactions". Synthesis 1999 06 (1999): 1013-1016. http://dx.doi.org/10.1055/s-1999-3506.
    10.1055/s-1999-3506
  136. Queiroz, Maria-João Rp.; Guglielmetti, Robert. "Synthesis of Photochromic Thieno-2H-Chromenes". Phosphorus, Sulfur, and Silicon and the Related Elements 153 1 (1999): 397-398. http://dx.doi.org/10.1080/10426509908546489.
    10.1080/10426509908546489
  137. Herz, H.-G.; Queiroz, M.J.R.P.; Maas, G.. "2-arylvinylation of 1-methylindole by palladium-catalyzed cross-coupling reactions". Synthesis 6 (1999): 1013-1016. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033035311&partnerID=MN8TOARS.
  138. Gonçalves, M.S.T.; Oliveira-Campos, A.M.F.; Pinto, E.M.M.S.; Plasência, P.M.S.; Queiroz, M.J.R.P.. "Photochemical treatment of solutions of azo dyes containing TiO2". Chemosphere 39 5 (1999): 781-786. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033180975&partnerID=MN8TOARS.
    10.1016/S0045-6535(99)00013-2
  139. Martins, M.A.M.; Cardoso, M.H.; Queiroz, M.J.; Ramalho, M.T.. "Biodegredation of azo dyes by the yeast Candida zeylanoides in batch aerated cultures". Chemosphere 38 11 (1999): 2455-2460. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033121286&partnerID=MN8TOARS.
    10.1016/S0045-6535(98)00448-2
  140. Peixoto, Fernanda M. C.; Queiroz, M.-J. R. P.; Kirsch, Gilbert. Corresponding author: Queiroz, M.-J. R. P.. "Synthesis of Precursors of Linear Thienocarbazole Analogues of Ellipticine and Olivacine". Journal of Chemical Research 4 (1998): 172-173. http://dx.doi.org/10.1039/a705628a.
    10.1039/a705628a
  141. Dharmasena, Pryanthi; Oliveira-Campos, Ana M. F.; Queiroz, Maria-João R. P.; Raposo, M. Manuela M.; Shannon, Patrick V. R.; Webb, Christine. Corresponding author: Shannon, Patrick V. R.. "Antitumour Heterocycles. Part 16.1 The Synthesis of 7,10-Dimethoxyellipticine and its Pyrrolo[2,3-f]carbazole and Pyrrolo[3,2-f] Analogues". Journal of Chemical Research 11 (1997): 398. http://dx.doi.org/10.1039/a704615d.
    10.1039/a704615d
  142. Chunchatprasert, L.; Dharmasena, P.; Oliveira-Campos, A.M.F.; Queiroz, M.J.R.P.; Raposo, M.M.M.; Shannon, P.V.R.. "Anti-tumour Heterocycles. Part 13.1 The Syntheses of Two New Pyridocarbazoles (Ellipticines) and Some Pyrrolocarbazole Analogues". Journal of Chemical Research - Part S 2 (1996): 84-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-2742566263&partnerID=MN8TOARS.
  143. Dharmasena, P.; Oliveira-Campos, A.-M.F.; Queiroz, M.-J.R.P.; Shannon, P.V.R.. "Antitumour Heterocycles. Part 12. The Synthesis of New Hydroxypyrrolocarbazoles and Hydroxypyridocarbazoles". Journal of Chemical Research - Part S 1 (1996): 12-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-2742555371&partnerID=MN8TOARS.
  144. Joseph, Delphine; Queiroz, Maria-João R. P.; Kirsch, Gilbert. Corresponding author: Kirsch, Gilbert. "IMPROVED PREPARTION OF 2,5-DIMETHYL-1,3-CYCLOHEXANEDIONE". Organic Preparations and Procedures International 27 4 (1995): 499-500. http://dx.doi.org/10.1080/00304949509458486.
    10.1080/00304949509458486
  145. Queiroz, Maria-Joao; Joseph, Delphine; Kirsch, Gilbert. "IMPROVED PREPARATION OF 2,5-DIMETHYL-1,4-CYCLOHEXANEDIONE". Organic Preparations and Procedures International 27 1 (1995): 120-122. http://dx.doi.org/10.1080/00304949509458191.
    10.1080/00304949509458191
  146. Oliveira-Campos, A.M.F.; Queiroz, M.-J.R.P.; Raposo, M.M.M.; Shannon, P.V.R.. "A synthesis of 8,10-dimethoxyellipticine via a diphenylamine". Tetrahedron Letters 36 1 (1995): 133-134. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028894577&partnerID=MN8TOARS.
    10.1016/0040-4039(94)02193-F
  147. Hall, R.J.; Dharmasena, P.; Marchant, J.; Oliveira-Campos, A.-M.F.; Queiroz, M.-J.R.P.; Raposo, M.M.; Shannon, P.V.R.. "A flexible approach to pyrido[4,3-b]carbazoles. The syntheses of 8,10-dimethoxy-5-methyl-, 5,11-dimethoxy-7,10-dimethyl- and 9-fluoro-5,11-dimethylpyrido[4,3-b]carbazoles by variations of the 'type D' route". Journal of the Chemical Society, Perkin Transactions 1 16 (1993): 1879-1889. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049071080&partnerID=MN8TOARS.
  148. OLIVEIRA-CAMPOS, A.-M.; Queiroz, Maria-João R. P.; SHANNON, P. V. R.. Corresponding author: OLIVEIRA-CAMPOS, A.-M.. "ChemInform Abstract: A Facile Preparation of Carbazoles and Relay Syntheses of Several Ellipticines (II) by Photochemical Cyclization-Deprotection of N,N- Diarylsulfonamides (I).". Chemistry and iIndustry 23 17 (1992): http://dx.doi.org/10.1002/chin.199217150.
    10.1002/chin.199217150
  149. Hall, R.J.; Marchant, J.; Oliveira-Campos, A.M.F.; Queiroz, M.-J.R.P.; Shannon, P.V.R.. "The synthesis of pyrido[4,3-b]carbazoles from diphenylamine derivatives: Alternative routes to and relay syntheses of ellipticines and olivacines". Journal of the Chemical Society, Perkin Transactions 1 24 (1992): 3439-3450. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049072530&partnerID=MN8TOARS.
  150. Hall, R.J.; Jackson, A.H.; Oliveira-Campos, A.M.F.; Queiroz, M.-J.R.P.; Shannon, P.V.R.. "Synthesis of key carbazoles - intermediates for polymethoxyellipticines and olivacines". Heterocycles 31 3 (1990): 401-405. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001361166&partnerID=MN8TOARS.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/11 Synthesis of Mono- or Di-(hetero)aryl 2-Pyranones Fused with N,S-Heterocycles V- Simpósio IberoAmericano de Química Orgânica(V-SIBEAQO)/V- IberoAmerican Symposiumon Organic Chemistry
University of Santiago de Compostela (El Grove, Spain)
2024/01/24 Selected for oral presentation: Synthesis of new di(hetero)arylamines derivatives of thieno[3,2-b]pyridines and evaluation of their neuroprotective activity on transgenic Caenorhabditis elegans for Machado Joseph disease 15º Encontro Nacional de Química Orgânica & 8º Encontro Nacional de Química Teraêutica
Universidade do Algarve (Faro, Portugal)
2024/01/23 Selected for Flash communication: Synthesis of Sonogashira coupling products in the thieno[2,3-b]pyrazine series and cyclizations to tricyclic lactones 15º Encontro Nacional de Química Orgânica & 8º Encontro Nacional de Química Terapêutica
Universidade do Algarve (Faro, Portugal)
2023/09 Invited oral communication: Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and In Vitro and In Ovo Antitumoral Evaluation Molecules4Life I International Meeting 2023
Universidade de Trás-os- Montes e Alto Douro (Vila Real, Portugal)
2023/05/16 Invited oral communication: Synthesis and Evaluation of Novel Heterocyclic Compounds as Antitumorals and/or Antiangiogenics XV Jornadas Bioquímica / Biochemistry Journeys
Universidade de Trás-os- Montes e Alto Douro (Vila Real, Portugal)
2023/02/10 Synthesis of heterocyclic compounds with biological properties Cost Meeting- Action CA21130 PRESTO "P2X receptors as therapeutic targets”,
Universitat di Ferrara (Ferrara, Italy)
2021/09 Rodrigues, Juliana M.; Cendon, Borja; Gulias, Moises; Mascarenas, José Luís; Queiroz, Maria-João R. P. Rh(III)-catalyzed Formal (4+2) Cycloaddition between Thienopyridine/thienopyrazine Carboxylic Acids and Alkynes, Triggered by C-H Activation, International Symposium on Synthesis and Catalysis (ISYSYCAT2021), Universidade de Évora, 31 Aug-3 Sept 2021, Évora, Portugal. International Symposium on Synthesis and Catalysis (ISYSYCAT2021)
Universidade de Évora (Évora, Portugal)
2018/09/18 Juliana M. Rodrigues, Sabine Berteina-Raboin, Maria-João R. P. Queiroz. "Synthesis of novel 8-(het)aryl-6H-pyrano[4,3:4,5]thieno[3,2-b]pyridines" 22nd International Conference on Organic Synthesis
(Florence, Italy)
2018/09/16 Joana F. Campos, Sabine Berteina-Raboin, Maria-João R.P. Queiroz . "Synthesis of novel pyrazinothienotriazolopyrimidinones and triazolylthienopyrazynes", OC5 12th National Meeting Organic Chemistry/5th National Meeting of Therapeutic Chemistry
(Coimbra, Portugal)
2018/07/13 Invited Oral Communication: A. Francisca Mota, Andreia Teixeira-Castro, Patrícia Maciel, Maria-João R.P. Queiroz. "Synthesis of new di(hetero)arylamines derivatives of thieno[3,2-b]pyridines and evaluation of their neuroprotective activity on transgenic Caenorhabditis elegans for Machado Joseph disease as a model of study and toxicity" Annual GP2A (Groupement des Pharmochimistes de l'Arc Atlantique) Medicinal Chemistry Conference
(Asnelles sur Mer – Caen, France)
2017/08/31 Invited Oral Communication: Maria-João R. P. Queiroz, Vera Machado, Daniela Peixoto, Raquel Soares. "New dual antiangiogenic and anti-breast cancer 1-aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas" 25th Annual GP2A (Groupement des Pharmochimistes de l'Arc Atlantique) Medicinal Chemistry Conference
(Liverpool, United Kingdom)
2016/09/26 Invited Oral Communication: Maria-João R. P. Queiroz. "Functionalization of heterocyclic compounds with potential biological activity by C-H activation" In the scope of the COST Action CA15106 C-H Activation in Organic Synthesis (CHAOS)
(Wien, Austria)
2015/09/02 Maria-João R.P. Queiroz, Juliana M. Rodrigues, Daniela Peixoto, Ricardo C. Calhelha. "Synthesis of alkyl 3-aminothieno[3,2-b]pyridine-2-carboxylates derivatives by metal-catalyzed reactions and driven intramolecular cyclizations" International Symposium of Synthesis and Catalysis - SynCatSyn15
(Évora, Portugal)
2015/08/04 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis and evaluation of new thienopyrimidine/pyridine derivatives as antitumoral and/or antiangiogenic" 3rd International Conference on Integrative Biology
(Valencia, Spain)
2013/09/04 Maria João R. P. Queiroz, Agathe Begouin, Daniela Peixoto. "New strategies for the synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridine scaffolds from 2,3-dihalopyridines", OC1 10º Encontro Nacional de Química Orgânica-1º Simpósio Luso-Brasileiro de Química Orgânica (10ENQO-1SLB)
(Lisboa, Portugal)
2013/05/17 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis and evaluation of the antitumor and/or antiangiogenic potential of new heterocyclic compounds" 1º Simpósio de Química Medicinal da Universidade do Minho
(Braga, Portugal)
2013/04/20 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis and evaluation of the antitumor and/or antiangiogenic potential of new heterocyclic compounds" IV Jornadas de Farmácia - 1st Annual Meeting Coimbra Health School
(Coimbra, Portugal)
2013/04/10 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis and evaluation of the antitumor and/or antiangiogenic potential of new heterocyclic compounds" VI Jornadas de Bioquímica Univ. de Trás-os-Montes e Alto Douro
(Vila Real, Portugal)
2013/04/05 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis and evaluation of the antitumoral/antiangiogenic potential of new heterocyclic compounds" Universidade de Évora
(Évora, Portugal)
2013/03/14 Invited Oral Communication: Maria João R. P. Queiroz. "Evaluation of the antitumor and/or antiangiogenic potential of new heterocyclic compounds" IV Jornadas Nacionais de Ciências Biomédicas, Universidade de Aveiro
(Aveiro, Portugal)
2013/01/09 Invited Oral Communication: Maria João R. P. Queiroz. "New thienopyridine and thienopyrimidine derivatives as antitumorals and/or antiangiogenics with tyrosine kinase membrane receptors as targets" 2nd workshop on Medicinal Chemistry - Dept de Química e Bioquímica, Fac. Ciências, Universidade do Porto
(Porto, Portugal)
2012/11/28 Maria João R. P. Queiroz, Daniela Peixoto, Ricardo C. Calhelha, Rui M.V. Abreu, Hugo J. C. Froufe, Isabel C.F. R. Ferreira, Raquel Costa, Raquel Soares. "Synthesis, docking and cellular assays of thieno [3,2-b]pyridine-thioether-1,3-diaryureas as VEGFR2 inhibitors", OC13 3rd Portuguese Meeting on Medicinal Chemistry/ 1st Portuguese-Spanish-Brazilian Meeting on Medicinal chemistry
(Aveiro, Portugal)
2012/03 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis of new potential antitumor heterocyclic compounds. Interaction with DNA and encapsulation in nanoliposomes, monitored by fluorescence." III Jornadas Bioquímica, Universidade do Minho
(Braga, Portugal)
2011/08/31 Maria João R. P. Queiroz, Ricardo C. Calhelha, S. Dias, Daniela Peixoto. "Synthesis of 1,3-diaryl(thio)ureas in the thieno[3,2-b]pyridine series by palladium-catalyzed couplings and reactions with aryliso(thio)cyanates" 23rd International Congress on Heterocyclic Chemistry
(Glasgow, United Kingdom)
2011/07/03 Rui Abreu, Hugo Froufe, Isabel C.F.R. Ferreira, Maria-João R.P. Queiroz. "Rational design of thieno[3,2-b]pyridines as potential new VEGFR-2 inhibitors based on improved docking scores" XXII Encontro Nacional da Sociedade Portuguesa de Química (SPQ)
(Braga, Portugal)
2011/07/03 Sandrina A. Heleno, Lillian Barros, Anabela Martins, Maria João R.P. Queiroz, Celestino Santos-Buelga, Isabel C.F.R. Ferreira. "Phenolic compounds and antioxidant activity of fruiting body and spores of wild Ganoderma lucidum" XXII Encontro Nacional da Sociedade Portuguesa de Química (SPQ)
(Braga, Portugal)
2008/10/03 Invited Oral Communication: Maria João R. P. Queiroz, Paula M. T. Ferreira, Ana Abreu, Elisabete Castanheira, Luís Vale-Silva, Eugénia Pinto, M. São-José Nascimento. "Synthesis of Fluorescent Heteroaromatic Compounds Using Dehydroamino Acids as Building Blocks, Studies of DNA, and Biomembranes Interactions. Evaluation of Antiproliferative Effects on Tumor Cell Lines" Ehrlich II-2nd World Conference on Magic Bullets
(Nuremberg, Germany)
2008/09/09 Agathe Begouin, Maria-João R. P. Queiroz, Goreti Pereira, Paula M. T. Ferreira. "A New Synthesis of substituted pyrrole-2-carboxylates by a tandem Sonogashira coupling / 5-endo-dig-cyclization from a beta-iododehydrophenylalanine and terminal alkynes" 23rd European Colloquium on Heterocyclic Chemistry
(Antwerp, Belgium)
2008/04/14 Invited Oral Communication: Maria João R. P. Queiroz. "Síntese de novos compostos heterocíclicos e estudo de potenciais aplicações biológicas" I Jornadas de Bioquímca, Universidade de Trás-os-Montes e Alto Douro
(Vila Real, Portugal)
2007/09/21 Maria João R. P. Queiroz. "Tandem metal-catalyzed Sonogashira coupling and intramolecular cyclization towards the synthesis of 3-(aryl)benzothieno[2,3-c]pyran-1-ones ", OC12 8º Encontro da Divisão de Catálise e Materiais Porosos da Sociedade Portuguesa de Química
(Lamego, Portugal)
2007/07/15 Invited Oral Communication: Maria João R. P. Queiroz. "Metal-Assisted reactions in the synthesis of new Fluorescent Heteroaromatic Systems from Dehydroamino Acid Derivatives" 7º Encontro Nacional de Química Orgânica (7ºENQO)
(Lisboa, Portugal)
2007/07/01 Maria-João R. P. Queiroz, Paula M. T. Ferreira, Ana S. Abreu, M. Solange D. Carvalho, Ricardo C. Calhelha. "Reactivity of Methyl Esters of N-Boc-beta,beta-disubstituted Dehydroamino Acids Towards the Synthesis of Lactams and Lactones" 11th European Symposium on Organic Reactivity
(Faro, Portugal)
2007/04/28 Maria-João R. P. Queiroz, M. Solange D. Carvalho, Teresa C. T. Lopes, Elisabete M. S. Castanheira, Paula M. T. Ferreira, Giampietro Viola. "New tetracyclic antitumoral compounds including benzo[b]thiophene or dibenzothiophene units: synthesis, DNA, interaction and biological studies" First Iberic Meeting on Medicinal chemistry: Anticancer Agents
(Régua, Portugal)
2006/09/02 Maria-João R. P. Queiroz, M. Solange D. Carvalho, Elisabete M. S. Castanheira, Paula M. T. Ferreira. "Synthesis and DNA interaction of a new benzothienoindole" XXII European Congress of Heterocyclic Chemistry
(Bari, Italy)
2005/07/31 Queiroz, M.-J.R.P.; Abreu, A. S.; Ferreira, P. M. T. Synthesis of Heterocyclic Amino Acid Derivatives by Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted C-N Intramolecular Cyclization 20th International Congress of Heterocyclic Chemistry (20thICHC)
International Society of Heterocyclic Chemistry (Palermo, Italy)
2005/07/20 Invited Oral Communication: Maria João R. P. Queiroz. "Palladium-Catalyzed Cross-Couplings (C-C and C-N) in the Benzo[b]thiophene Series: Diarylamines, Tetracyclic Compounds and Benzo[b]thienylamino Acids" 6º Encontro Nacional de Química Orgânica (ENQO6)
(Braga, Portugal)
2004/11/24 Invited Oral Communication: Maria João R. P. Queiroz. "Biodegradation of bioaccessible azo dyes by ligninolytic fungi" Mycrobiology Institut - Check Republic Academy
(Pargue, Czech Republic)
2004/09/12 Maria João R. P. Queiroz, Ana S. Abreu, Paula M. T. Ferreira, André Samat, Jean Aubard, Roger Dubest-. "Synthesis of photochromic thieno-2H-chromenes and linkage to an amino acid using an aromatic spacer" 4th International Symposium on Photochromism ISOP’04
(Arcachon, France)
2003/11/21 Invited Oral Communication: Maria João R. P. Queiroz. "Palladium-catalyzed (C-C and C-N) cross couplings in the synthesis of benzo[b]thiophene derivatives" Université de Nancy
(Nancy, France)
2003/09/10 Agathe Begouin, Isabel C. F. Ferreira, Maria-João R. P. Queiroz and Gilbert Kirsch. "Palladium-catalyzed amination of electron-rich or poor benzo[b]thienyl bromides" 13th European Symposium of Organic Chemistry
(Croatia)
2001/09/09 Invited Oral Communication: Maria João R. P. Queiroz. "Síntese de tienocarbazolas com potencial actividade anti-tumoral" Faculdade de Ciências, Departamento de Química, Universidade do Porto
(Porto, Portugal)
2001/07 Invited Oral Communication: Maria João R. P. Queiroz. "Synthèse de composés polyheterocycliques pour application biologique et photochimique" Université de Metz
(Metz, France)
2001/06 Invited Oral Communications: Maria João R. P. Queiroz. "Synthesis of potential anti-tumoral thienocarbazoles by several methods" Selected to represent Portugal by CERC3 - Workshop CERC3
(Champery, Switzerland)
1998/04 Invited Oral Communication: Maria João R. P. Queiroz. "Synthesis of benzo[b]thiophenes derivatives with several industrial applications: Biological Active Compounds, Photochromic Compounds and azo Dyes" Universty of Ulm
(Ulm, Germany)
1994/04 Invited Oral Communication: Maria João R. P. Queiroz. "Synthèse de precurseurs d’ellipticines" Université de Metz
(Metz, France)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/09 - Current Synthesis of novel fused N,S-heterocycles with potential bilogical activity
Supervisor of Maria F. Martins
 Medicinal Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
2021/10 - 2022/12/09 Synthesis of new conjugates of S and N,S-heterocycle-dipeptides potentially antitumoral; formation and characterization of a hydrogel
Supervisor of Ana Morgana Gonçalves Pereira da Silva
Master in Medicinal Chemistry (Master)
Universidade do Minho Escola de Ciências, Portugal

Universidade do Minho Departamento de Química, Portugal
2017/05 - 2021/11/02 Synthesis of new potential biological active compounds based on thiophere fused N-heterocycle scaffolds using cross-couplings, C-H activation and intra/intermolecular cyclizations (SFRH/BD/115844/2016)
Supervisor of Juliana Patrícia de Moura Rodrigues
 Química Aplicada (PhD)
Universidade do Minho, Portugal
2019/09 - 2020/01 Synthesis of fused heteroaromatic compounds of N and S with potential biological activity
Supervisor of Ana Patrícia de Carvalho Lourenço
 Química Medicinal (Master)
Universidade do Minho, Portugal
2018/09 - 2020/01 Synthesis of fused heteroaromatic of N and/or S compounds and antitumor evaluation in human tumor cell lines
Supervisor of Bruna Daniela Rodrigues da Silva
 Bioquímica Aplicada - Especialidade Biomedicina (Master)
Universidade do Minho, Portugal
2015 - 2016 Synthesis of new hetetocyclic compounds of S and/or N with potencial application in SNC diseases using as a model of activity and toxicity the nematod Caenorhabditis elegans
Supervisor of Ana Francisca Ferreira da Mota
 Química Medicinal/ medcicinal Chemistry (Master)
Universidade do Minho, Portugal
2012 - 2016 Synthesis of novel heterocyclic compounds based on rational design and evaluation of their antitumor and antiangiogenic potential in human endothelial and tumor cell lines with tyrosine kinase membrane receptors as targets (SFRH/BD/77373/2011)
Supervisor of Vera Alexandra Pereira Machado
 Ciências (PhD)
Universidade do Minho, Portugal
2014 - 2015 Síntese de novas tieno[3,2-b]piridinas com potencial atividade biológica contendo 1,2,3-triazoles 1,4-dissubstituídos obtidos por reação "click" de ciclioadição azida-alquino catalisada por Cu(I) - CuAAC
Supervisor of Juliana Patrícia de Moura Rodrigues
 Química Medicinal (Master)
Universidade do Minho, Portugal
2012 - 2015 Towards antioxidant and antitumoral properties of wild medicinal plants traditionally used in Portugal: extracts, isolated flavonoids, and their human metabolites obtained by chemical synthesis (SFRH/BD/78307/2011)
Supervisor of Cristina Rafaela dos Santos Albuquerque Guimarães
 Ciências (PhD)
Universidade do Minho, Portugal
2010 - 2014 Important human metabolites of phenolic acids from diet with wild mushrooms: chemical synthesis and studies of their antioxidant, antitumor and antimicrobial properties (SFRH/BD/70304/2010)
Supervisor of Sandrina Alves Heleno
 Ciências (PhD)
Universidade do Minho, Portugal
2012 - 2013 Síntese de novos derivados de tienopiridinas como potenciais antitumorais e antiangiogénicos tendo como alvos receptores membranares de tirosina cinase in the scope of the project PTDC/QUI-QUI/111060/2009
Supervisor of Joana Filomena Mimoso Silva de Campos
 Química Medicinal (Master)
Universidade do Minho, Portugal
2009 - 2013 New heterocyclic bioactive fluorescent compounds: spectroscopic studies of DNA interactions and encapsulation in nanoliposomes (SFRH/BD/47052/2008)
Supervisor
 Ciências (PhD)
Universidade do Minho, Portugal
2011/09 - 2012/12 Síntese compostos tricíclicos derivados de tieno[3,2-b]piridinas e de 1,3-diarilureias derivadas de tieno[3,2-d]pirimidinas como potenciais antitumorais e/ou antiangiogénicos in the scope of the project PTDC/QUI-QUI/111060/2009
Supervisor of Hugo Ricardo Matos Viana
 Medicinal Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
2011/09 - 2012/10 BI grant holder in the scope of project PTDC/QUI-QUI/111060/2009
Supervisor of Daniela Silva Peixoto
Universidade do Minho, Portugal
2010/09 - 2011/12 Synthesis of new thienopyridine derivatives as potential antitumor and/or antiangiogenic (in the scope of the project PTDC/QUI-QUI/111060/2009)
Supervisor of Daniela Alexandra Silva Peixoto
 Medicinal Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
2010/09 - 2011/11 Synthesis of new thienopyridine and thienopyrimidine derivatives as potential antitumor and/or antiangiogenic in the scope of the project PTDC/QUI-QUI/111060/2009.
Supervisor of Pedro Henrique Gomes Soares Peixoto
 Chemistry (Master)
Universidade do Porto, Portugal
2007 - 2011/07 Antioxidant activity of diarylamines in the benzo[b]thiophene series and antitumoral/antiangiogenic activity of thieno[3,2-b]pyridine derivatives: In vitro studies, QSAR modelling, VEGFR-2 docking and software development (SFRH/BD/27430/2006 that changed into SFRH/PROTEC/49450/2009)
Supervisor of Rui Miguel Vaz Abreu
 Molecular Genetics (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2006 - 2010/09/29 Síntese de Novos Compostos Heterocíclicos Derivados de Benzo(b)tiofenos e Tieno[3,2-b]Piridinas Usando Acoplamentos Catalisados por Metais. Estudos de Actividade Biológica (SFRH/BD/29274/2006)
Supervisor of Manuel Ricardo Costa Calhelha
 Ciências (PhD)
Universidade do Minho, Portugal
2009 - 2010 Synthesis of new thieno[3,2-b]pyridines using Pd and Cu-catalyzed C-O, C-C and C-N couplings and reactions with arylisocyanates, as potential antitumorals and antiangiogenics
Supervisor of Natália Sofia Dias
 Medicinal Chemistry (Master)
Universidade do Minho, Portugal
2006/09 - 2008/08 BI grant holder in the scope of the project POCI/QUI/59407/2004
Supervisor of Maria Goreti Carvalho Pereira
2006 - 2007 Synthesis of new tetracyclic heteroaromatic compounds as potential antimorals, by metal-assisted intramolecular cyclization of beta,beta-diaryldehydroamino acids. Studies of absorption and fluorescence in solvents and in the presence of DNA
Supervisor of Maria Solange Dantas Carvalho
 Química (Master)
Universidade do Minho, Portugal
2002 - 2006/04 Synthesis of benzo[b]thienylamino acids and intramolecular C-N cyclization to bi and tricyclic heteroaromatic systems. Studies of fluorescence, photochromism and biological activity (SFRH/BD/4709/2001)
Supervisor of Ana Sofia Abreu
 Sciences - Chemistry (PhD)
Universidade do Minho, Portugal
2005 - 2006/03 Synthesis of functionalized benzo[b]thiophenes and linkage to dehydroamino acids by Suzuki coupling
Supervisor of Natália Oliveira Silva
 Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
1998 - 2006 Estudos de Biodegradação de Corantes de Aplicação Têxtil Bioacessíveis a Fungos Lenhinolíticos (Praxis XXI BD/15878/98)
Supervisor of Maria Adosinda Monteiro Martins
 Ciências (PhD)
Universidade do Minho, Portugal
2005/04 - 2005/06 Amination catalysée par le palladium de derivés halogenés du benzo[b]thiophène avec la 4-fluoroaniline et des aminopyridines
Supervisor of Jeanne-Marie Begouin
 Chemistry (Degree)
Universidade do Minho, Portugal

Université de Metz, France
2004/04 - 2004/06 Couplages croisés catalisés par le palladium dans la synthèse de derivés du benzo[b]thiophène
Supervisor of Yanick De Gaetano
 Chemistry (Degree)
Universidade do Minho, Portugal

Université de Metz, France
2002 - 2003/07 Synthesis of linear and angular photochromic compounds derivatives of methylated benzo[b]tiophenes
Supervisor of Paula Marina Plasencia
 Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
1999 - 2003/07 Palladium-catalyzed cross-couplings (C-C and C-N) in the synthesis of tetracyclic heteroaromatic compounds derivatives of benzo[b]thiophenes
Supervisor of Isabel Cristina Ferreira
 Sciences - Chemistry (PhD)
Universidade do Minho, Portugal
2003/04 - 2003/06 Synthèse de diarylamines dérivées du 3-bromo-2-carbéthoxybenzo[b]thiophène par couplages C-N catalysés par le palladium
Supervisor of Agathe Begouin
Chemistry (Degree)
Universidade do Minho, Portugal

Université de Metz, France
2003 - 2003 Acoplamentos Cruzados Catalisados por Paládio (C-C e C-N) na Síntese de Compostos Tetracíclicos Heteroaromáticos Derivados de Benzo(b)tiofenos
Supervisor
 Ciências (PhD)
Universidade do Minho, Portugal
2002/04 - 2002/06 Synthèse de benzo[b]thiophenes fonctionalisés, précurseurs des molecules avec activité biologique
Supervisor of Audrey Tardieu
 Chemistry (Degree)
Universidade do Minho, Portugal

Université de Metz, France
1999 - 2000 BI grant holder in the scope of the project POCTI/1999/QUI/32689
Supervisor of Natália Silva
Universidade do Minho, Portugal
1999 - 2000 Síntese de benzo[b]tiofenos precursores de compostos fotocrómicos
Supervisor of Fernanda Isabel Dias Rocha
 Chemistry (Degree)
Universidade do Minho, Portugal
1998 - 1999/02 Synthesis and biodegradation of textile azo dyes by the white-rot fungus Phanerochaete chrysosporium
Supervisor of Isabel Cristina Ferreira
 Environmental Sciences (Master)
Universidade do Minho Departamento de Engenharia Biológica, Portugal
1998 - 1999 Síntese e aplicação de novos corantes azo reactivos derivados de benzo[b]tiofenos
Supervisor of Cristina Ribeiro
 Chemistry (Degree)
Universidade do Minho, Portugal
1996 - 1997/06 Biodegradation Studies of textile azo dyes by Candida zeynaloides
Supervisor of Maria Adosinda Martins
 Environmental Sciences (Master)
Universidade do Minho Departamento de Química, Portugal
1996 - 1997/04 Synthesis of key compounds for the preparation of thienocarbazoles with potential biological activity
Supervisor of Fernanda Maria Peixoto
 Chemistry (Master)
Universidade do Minho Departamento de Química, Portugal
1996 - 1996/10 Síntese e Estudos de Degradação (biológica e fotocatalítica) de Corantes azo de Aplicação Têxtil
Supervisor of Paula Marina de Sousa Plasencia
 Chemistry (Degree)
Universidade do Minho, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2022/02/09 Development of new supramolecular hypergelators based on non-natural amino acid residues
(Thesis) Main arguer
 Carlos Bruno Pereira Oliveira (Master)
Universidade do Minho, Portugal
2017/12/15 Development of novel synthetic strategies towards azaindoles as promising COXs inhibitors
(Thesis) Main arguer
 Marina Joana Dias Pires (PhD)
Universidade Nova de Lisboa, Portugal
2015/12/08 Pyrrolo[2,3-d]pyrimidines : Conception, Synthèse, Fonctionnalisation et Activité Biologique
(Thesis) Main arguer
 Vanessa Prieur (PhD)
Université d'Orléans, France
2014/12/19 Optimized molecular imaging agents: from metal chelates to micelles to gold nanoparticles
(Thesis) Arguer
 Miguel Filipe Moreira Marques Ferreira (PhD)
Universidade do Minho, Portugal

University of Ulm, Germany
2014/05 Triazapolylcarboxylate-based Ga(III) and Mn(II) chelates for medical imaging (PET, gamma-scintigraphy and MRI)
(Thesis) Arguer
 Arsénio Vasconcelos de Sá (PhD)
Universidade do Minho, Portugal
2013/04/05 Synthesis and evaluation of Chiral Phosphine and NHC Ligands for Heterogeneous Asymmetric Catalysis
(Thesis) Main arguer
 Carolina Silva Marques (PhD)
Universidade de Évora, Portugal
2012/07/12 Dehydroamino acids as building blocks for the synthesis of new amino acid derivatives
(Thesis) Arguer
 Maria Goretti Carvalho Pereira (PhD)
Universidade do Minho, Portugal
2010/12/20 Caracterização Biológica, Química e Nutricional de Castanea sativa Miller e Prunus dulcis (Miller) D.A. Webb Biological, Chemical and Nutritional Characterization of Castanea sativa Miller e Prunus dulcis (Miller) D.A. Webb
(Thesis) Main arguer
 João Carlos Martins Barreira (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2007/09 Réalisation de couplages pallado-catalysés en série thiophénique. Synthése des composés biologiquement actifs
(Thesis) Main arguer
 Agathe Begouin (PhD)
Université de Metz, France
2007/06 Síntese de novos macrociclos tetrapirrólicos /Synthesis of new tetrapyrrole macrocycles
(Thesis) Arguer
 Paula Sofia Sarrico Lacerda (PhD)
Universidade de Aveiro, Portugal
2002/12 Synthèse d´analogues thiophéniques dês paullones, agents antitumouraux potentiels
(Thesis) Main arguer
 Evelyne Mignaiu (PhD)
Université de Metz, France
1996/11 Compostos heterocíclicos para aplicações ópticas/ Heterocyclic compounds for optical applications
(Thesis) Arguer
 Susana Paula Graça da Costa (PhD)
Universidade do Minho, Portugal

Association member

Society Organization name Role
2024/02 - Current International Society of Heterocyclic Chemistry Member
1990 - Current Sociedade Portuguesa de Química Member
1995 - 2011 International Society of Heterocyclic Chemistry Member
1997 - 2000 European Photochemistry Association (EPA) Member

Committee member

Activity description
Role 		Institution / Organization
2022/10/04 - 2026/10/03 COST action CA21130 P2X receptors as a therapeutic opportunity (PRESTO)
Member
 Università degli Studi di Ferrara, Italy
2016/03/03 - 2020/03/20 COST ACTION CA15106 C-H activation in Organic Synthesis Participation in several scientific meetings in different countries integrating the Action (Austria, Great Britain, Bulgaria, Cyprus, Spain, Malta)
Member
 Technische Universität Wien, Austria

Conference scientific committee

Conference name Conference host
2023/09/20 - 2023/09/22 I International Meeting Molecules4Life 2023, Vila Real, Portugal Universidade de Trás-os- Montes e Alto Douro
2023/09/05 - 2023/09/08 International Symposium on Synthesis and Catalysis (ISySyCat2023), Évora, Portugal University of Évora
2011/06/12 - 2011/06/15 2nd Iberic Meeting on Medicinal Chemistry, 2011, Fac. Ciências, Univ. Porto, Portugal. Universidade do Porto-Faculade de Ciências

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2017/09 - 2017/09 Invited Seminars: Click Chemistry: The Cu-catalyzed Azide-Alkyne Cycloaddition (CuAAC); Some insights in Transition Metal-Catalyzed C-H Activation of (Het)Arenes in the scope of ERASMUS Plus Teaching Mobility Chemistry (Master) Université d'Orléans, France
2016/09 - 2016/09 Invited Seminars: The Cu-catalyzed Azide-Alkyne Cycloaddition (CuAAC); Some insights in Transition Metal-Catalyzed C-H Activation of (Het)Arenes; Synthesis and functionalization of heterocyclic compounds with potential biological activity using metal-catalyzed C-C Suzuki and Sonogashira and C-N Buchwald-Hartwig in the scope of ERASMUS Plus Teaching Mobility Chemistry (Master) Université d'Orléans, France
2015/09 - 2015/09 Invited Seminars: Click Chemistry: The Cu-catalyzed Azide-Alkyne Cycloaddition (CuAAC) and Synthesis and functionalization of heterocyclic compounds with potential biological activity using metal-catalyzed C-C Suzuki and Sonogashira and C-N Buchwald-Hartwig in the scope of ERASMUS Teaching Mobility Chemistry (Master) Université d'Orléans, France
2014/09/21 - 2014/09/26 Invited Seminar: Click Chemistry: The Cu-catalyzed Azide-Alkyne Cycloaddition (CuAAC) in the scope of ERASMUS Teaching Mobility Chemistry (Master) Université d'Orléans, France
2013/09/25 - 2013/09/29 Invited Seminars: The Cu-catalyzed Azide-Alkyne Cycloaddition (CuAAC); Synthesis and functionalization of heterocyclic compounds with potential biological activity using metal-catalyzed C-C Suzuki and Sonogashira and C-N Buchwald-Hartwig couplings in the scope of ERASMUS Teaching Mobility Chemistry (Master) Université d'Orléans, France
2013/07/15 - 2013/07/24 Advance Course: Cancer therapy: from Basic Research to Clinic - "New heterocyclic compounds as antitumorals and antiangiogenics" Doctoral Program in Biologia Molecular e Ambiental (Doutoramento) Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2012/07/02 - 2012/07/02 Advanced Course: Pharmacological Development: from Organic Synthesis to Clinical Trials Doctoral Program in Biologia Molecular e Ambiental (Doutoramento) Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2008/09/21 - 2008/09/27 Invited Seminar: Synthesis of polyheterocyclic compounds with biological activity using metal assisted reactions in the scope of Programme Sócrates-Erasmus Université de Metz, France
2008/03/12 - 2008/03/12 Invited Seminar: Síntese e aplicações de derivados de benzo[b]tiofenos Instituto Politécnico de Bragança Escola Superior Agrária, Portugal
2006/09/24 - 2006/09/30 Invited Seminar: Palladium-catalyzed couplings of arylchlorides in the scope of the Programme Sócrates-Erasmus Université de Metz, France
2005/09/24 - 2005/09/29 Mild C-N copper-mediated arylations: some applications in the scope of the Programme Sócrates-Erasmus Université de Metz, France
2003/05/12 - 2003/05/16 Invited Seminar: Some applications of palladium-catalyzed amination of aryl halides or sulfonates in the scope of the Programme Sócrates-Erasmus Université de Metz, France

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2013 - 2019 Evaluation Committee for PhD grants attribution in the National Contest promoted by FCT.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia

Journal scientific committee

Journal title (ISSN) Publisher
2019 - Current Molecules (ISSN 1420-3049) MDPI

Mentoring / Tutoring

Topic Student name
2020/01/07 - 2020/03/13 Short-Term Scientific Mission: "C-H activation in the functionalization of thiophene fused N-heterocyles" Juliana Patrícia de Moura Rodrigues
2011/09 - 2016/08 Post-Doctoral Project (SFRH/BPD/68344/2010): "New antitumor and/or anti-angiogenic heterocyclic compounds: synthesis, molecular modelling and inhibition enzymatic assays using tyrosine kinase membrane growth factor receptors" Ricardo C. Calhelha
2006 - 2016 Post-Doctoral Project (SRFH/BPD/24548/2005): "Synthesis of new fluorescent aryl and heteroarylamino acids and photophysical studies on biological systems (DNA and lipid membranes)" Ana Sofia Abreu
2007 - 2014 Post-Doctoral Project (SFRH/BPD/36753/2007 ): "Metal assisted multicomponent reactions in the synthesis of heterocycles from amino acid derivatives, including the us of microwave irradiation" Agathe Begouin
2009/01 - 2013/07 Post-Doctoral Project (SFRH/BPD/46209/2008): "Wild edible Plants as a source of nutrients and nutraceuticals. Synthesis and characterization of flavonoid metabolites and studies of their bioactive properties" Lillian Bouçada de Barros
2007 - 2011 Post-Doctoral Project Silva (SFRH/BPD/29112/2006): "Study of the antifungal activity of new heterocyclic compounds including derivatives of dehydroamino acids and evaluation of mechanisms of action at molecular level" Luís André Vale Silva

Scientific expedition

Activity description Institution / Organization
2017/03/26 - 2017/03/31 Síntese de novos compostos heterocíclicos com potencial atividade biológica no cancro e/ou em doenças neurodegenativas, utilizando reações de ativação de ligações C-H. (Synthesis of new heterocyclic compounds with potential biological activity using C-H activation ractions) Establisment of a new scientific collaboration with Prof. José Luís Mascareñas of the CIQUS-Univ. Santiago de Compostela -Spain Funding: Program Iacobus Galicia-Spain and North of Portugal Universidade de Santiago de Compostela - Campus Vida, Spain
2000/04/01 - 2000/04/15 Síntese de tienocarbazoles bioisoteres of Piridocarbazoles anti-tumourais por ciclização de amino-1,3-dienos Consolidating the international collaboration with Prof. Maas of the University of Ulm -Germany. Funding Bilateral CRUP/DAAD Action nºA 24-99 Universität Ulm, Germany
1999/04 - 1999/04 Síntese de tienocarbazoles bioisoteres of Piridocarbazoles anti-tumourais por ciclização de amino-1,3-dienos Establishiment of a new international collaboration with Prof. Maas of the University of Ulm. Funding CRUP/DAAD Bilateral Action nºA 16-98 University of Ulm, Germany
1994/02/02 - 1994/07/31 Post-Doctoral work in the group of Prof. Gilbert Kirsch-Université de Metz-France, in the Synthesis of heteroaromatic compounds of nitrogen and sulfur wit potential antitumour activity Université de Metz, France
Distinctions

Other distinction

2001 Research Incitement Prize in Chemical Synthesis (as responsible for the executation of the work proposed))
Fundação Calouste Gulbenkian, Portugal