Curriculum Vitae
Bruno Fernando Bras da Silva
Identification
Personal identification
- Full name
- Bruno Fernando Bras da Silva
Citation names
- Silva, Bruno
- Silva, Bruno F. B.
Author identifiers
- Ciência ID
- F217-9E30-387B
- ORCID iD
- 0000-0002-8997-6311
Email addresses
- bruno.silva@empa.ch (Professional)
Addresses
- Empa, Lerchenfeldstrasse 5, 9014, St. Gallen, St. Gallen, Switzerland (Professional)
Knowledge fields
- Exact Sciences - Chemical Sciences - Colloid Chemistry
- Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
- Exact Sciences - Chemical Sciences - Physical Chemistry
Languages
| Language | Speaking | Reading | Writing | Listening | Peer-review |
|---|---|---|---|---|---|
| Portuguese (Mother tongue) | |||||
| English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
| Spanish; Castilian | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Beginner (A1) | |
| German | Beginner (A1) | Beginner (A1) | Beginner (A1) | Beginner (A1) |
Education
| Degree | Classification | |
|---|---|---|
|
2009/07/31
Concluded
|
Doutoramento em Química (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal
"Phase Behavior of Asymmetric Catanionic Surfactants: Equilibrium, phase transitions and microstructure" (THESIS/DISSERTATION)
|
Aprovado por unanimidade |
|
2004/07/28
Concluded
|
Licenciatura em Química, Ramo Científico (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Estudo do Comportamento Termotrópico de Tensioactivos Cataniónicos e Tensioactivos Gemini" (THESIS/DISSERTATION)
|
15 |
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 2023/01/01 - Current | Principal Investigator (Research) | Empa - Swiss Federal Laboratories for Materials Science and Technology, Switzerland |
| 2015/09/01 - 2022/02/28 | Principal Investigator (Research) | International Iberian Nanotechnology Laboratory, Portugal |
| International Iberian Nanotechnology Laboratory, Portugal | ||
| 2014/03/15 - 2015/08/31 | Visiting Researcher (Research) | University of California Santa Barbara, United States |
| University of California Santa Barbara, United States | ||
| 2013/03/01 - 2014/01/31 | Postdoc (Research) | Lunds Universitet Kemicentrum, Sweden |
| Lunds Universitet Kemicentrum, Sweden | ||
| 2011/02/01 - 2013/01/31 | Postdoc (Research) | University of California Santa Barbara, United States |
| University of California Santa Barbara, United States | ||
| 2009/10/01 - 2010/06/30 | Postdoc (Research) | Lunds Universitet Kemicentrum, Sweden |
| Lunds Universitet Kemicentrum, Sweden |
Projects
Contract
| Designation | Funders | |
|---|---|---|
| 2018/07/16 - 2021/07/15 | Microfluidic Layer-by-layer Assembly of Cationic Liposome - Nucleic Acid Nanoparticles for Gene Delivery
POCI-01-0145-FEDER-032520
Principal investigator
International Iberian Nanotechnology Laboratory, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
Outputs
Publications
| Journal article |
|
| Preprint |
|
Activities
Oral presentation
| Presentation title | Event name Host (Event location) |
|
|---|---|---|
| 2024/10/25 | Illuminating the Complexity with X-rays, neutrons and light: Structural Insights into Self-Assembled Lipid Systems, from Microemulsions to Lipid-DNA Nanoassemblies | Basel Campus Seminars, Novartis and Excelsus Structural Solutions, Basel, Switzerland
Novartis (Basel, Switzerland)
|
| 2024/06 | From Methodology to Insight: Unraveling the Assembly of Hybrid Core-Shell Bio-Inspired Polymer-Lipid Nanoparticles | Biointerface Science - Gordon Research Conference
GRC (Lucca (Barga), Italy)
|
| 2024/05/28 | Quantitative colocalization between nucleic acids, lipids & polymers with fluorescence cross-correlation spectroscopy | Applied Biophysics Forum in Drug Delivery
University of Copenhagen | Malvern (Copenhagen, Denmark)
|
| 2024 | Microfluidics with in-situ SAXS for time-resolved studies of liquid crystal dissolution | Swiss Soft Days
Paul Scherrer Institute (Villigen, Switzerland)
|
| 2023 | Advancements and challenges in nonviral gene therapeutics: A physical chemist’s perspective | International Meeting Molecules4Life
Universidade de Tras-os-Montes e Alto Douro (Vila Real, Portugal)
|
| 2023 | A Criterion for Predicting Stable Assembly of Lipid-Polymer-Nucleic Acid Nanoparticles | Controlled Release Society Annual Meeting & Exposition
CRS (Las Vegas, United States)
|
| 2023 | General assembly behavior of core- shell lipid-polycation-nucleic acid nanoparticles as revealed with fluorescence cross-correlation spectroscopy | Swiss Soft Days
Adolphe Merkel Institute (Fribourg, Switzerland)
|
| 2023 | Microfluidics with in-situ SAXS for time-resolved studies of liquid crystal dissolution | Annual Meeting Swiss Society for Crystallography
University of Zurich (Zurich, Switzerland)
|
| 2020/06/28 | Optimizing The Assembly Of Complex Gene Delivery Formulations With Fluorescence Cross Correlation Spectroscopy | Controlled Release Society Virtual Annual Meeting
Controlled Release Society (Virtual, United States)
|
| 2019/07/23 | Size-controlled Formation Of Cubosome Nanoparticles Using Microfluidics | Controlled Release Society Annual Meeting & Exposition
Controlled Release Society (Valencia, Spain)
|
| 2019/07/18 | Fluorescence Cross-Correlation Spectroscopy as a Valuable Tool to Monitor Cationic Liposome-DNA Nanoparticle Assembly | 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
|
| 2019/07/17 | Microfluidics for controlled self-assembly of cubosome nanoparticles of tunable size | 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
|
| 2019/07/17 | Pathway-dependent effects on the formation of bioreducible polycation-DNA polyplexes in saline media | 8th Iberian Meeting on Colloids and Interfaces-RICI8
Grupos de Colóides e Interfaces das Sociedades Portuguesa e Espanhola de Química (Aveiro, Portugal)
|
| 2018/12/11 | SAXS on a chip: from alignment phenomena at interfaces to dynamics of phase transitions studied with microfluidic devices | Workshop - Scattering and Dynamics of Flowing Soft Material
Lund Institute of Advanced Neutron and X-ray Science (LINXS) (Lund, Sweden)
|
| 2018/09/07 | SAXS on a chip: from alignment phenomena at interfaces to dynamics of phase transitions studied with microfluidic devices | 32nd Conference of the European Colloid and Interface Society
European Colloid and Interface Society (Ljubljana, Slovenia)
|
| 2018/05/29 | SAXS-on-a-chip: probing the time evolution of the lamellar-microemulsion transition in a microfluidic device | EUSMI/SoftComp Annual Meeting 2018
EUSMI and SoftComp (EU infrastructure networks) (Primosten, Croatia)
|
| 2018/03/13 | Pathway-dependent effects in the complexation of DNA with PEGylated Cationic Liposomes | Polyelectrolytes in Chemistry, Biology and Technology 2018
NTU - Nanyang Technological University, Singapore (Singapura, Singapore)
|
| 2017/07/07 | Soft self-assembled nanostructured nanoparticles for gene and drug delivery | VII Iberian Meeting of Colloids and Interface
Grupos de Colóides e Interfaces das Sociedades Espanhola e Portuguesa de Química (Madrid, Spain)
|
Supervision
| Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
|---|---|---|
| 2023 - 2025/01/27 | Elucidating Nano-scale Interactions Between Iron-carbohydrate Complexes and Complex Biological Environments Using Orthogonal
Methods
Co-supervisor
|
Empa - Swiss Federal Laboratories for Materials Science and Technology, Switzerland
Université de Fribourg Faculté de sciences et de médecine, Switzerland Empa Standort Sankt Gallen, Switzerland |
| 2020/12/01 - 2024/11/30 | Innovative dual-drug loaded cubosomes to tackle Pseudomonas aeruginosa infections in cystic fibrosis airway environment
Co-supervisor
|
Programa Doutoral Engenharia Biomédica (PhD)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2020/11/01 - 2024/10/31 | Chromene-based molecules for triple negative breast cancer therapy: synthesis, nanoencapsulation and biological studies
Co-supervisor
|
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2019/10/01 - 2024/10/22 | New Methods in Lipid-Based Nanosystems: From Microfluidic Mixing to Time-Resolved Quantification of PEG-Shedding in Lipid-Based
Nanoparticles
Co-supervisor
|
Física (MAP-FIS) (PhD)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2018 - 2022 | Nanomaterials for therapeutic purposes
Co-supervisor
|
International Iberian Nanotechnology Laboratory, Portugal
Universidade do Minho, Portugal |
| 2019/10/01 - 2021/05 | Microfluidics as nanoassemblers of soft self-assembled nanocarriers for drug delivery
Co-supervisor
|
Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2020/02/10 - 2020/08/25 | Exploring Polycation-DNA complexation for gene delivery using Fluorescence Cross-Correlation Spectroscopy
Co-supervisor of Xhorxhina Shaulli
|
Master in Chemistry from the University of Porto (Master)
Universidade do Porto Faculdade de Ciências, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2018/11/06 - 2020/06/25 | Monoolein cubosome formation using solvent-exchange in bulk and microfluidics: the effect of DODAB and DDAB addition
Co-supervisor of Maria Margarida da Silva Costa Barros
|
Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2017/10/16 - 2019/03/11 | Inhaled therapeutic strategies for cystic fybrosis-associated infections using nanoparticles-based drug delivery
Co-supervisor of Joana Margarida Dias Domingues
|
Master in Biotechnology (Master)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2017/10/02 - 2018/12/04 | Microfluidic methods for the controlled preparation of soft self-assembled nanocarriers for drug delivery
Co-supervisor of Celso Joel Oliveira Ferreira
|
Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
| 2017/01/01 - 2017/11/17 | Bulk and Microfluidic-Assisted Preparation of Bioreducible Polyplexes for Gene Therapy
Co-supervisor of Filipe Coelho
|
Mestrado em Química (Master)
Universidade do Porto Faculdade de Ciências, Portugal
International Iberian Nanotechnology Laboratory, Portugal |
Jury of academic degree
| Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
|---|---|---|
| 2018/12/14 | Microfluidic platforms for the validation of new targeted therapies for personalised medicine against osteosarcoma
(Thesis) Main arguer
|
Oihane Mitxelena (PhD)
Centro de Estudios e Investigaciones Técnicas de Gipuzkoa, Spain
Universidad de Navarra, Spain |
| 2018/01/31 | Development and characterization of cellulose based systems for the entrapment and delivery of probiotic bacteria
(Thesis) Arguer
|
Poonam Singh (PhD)
Universidade de Coimbra, Portugal
|
| 2017/02/17 | Combination of Microfluidics with SAXS for the investigation of pharmaceutical formulations
(Thesis) Main arguer
|
Aghiad Ghazal (PhD)
Københavns Universitet Niels Bohr Instituttet, Denmark
|
Distinctions
Other distinction
| 2012 | MRL-Dow travel fellowship |
| 2010 | AXA Research Fund Post-Doctoral Grants (recusei devido a conflito de datas com a bolsa Marie Curie IOF)
Fonds AXA pour la Recherche, France
|
| 2010 | Marie Curie International Outgoing Fellowship
Research Executive Agency, Belgium
European Commission, Belgium |
| 2009 | Bolsa no estrangeiro de curta duração
Fundação Calouste Gulbenkian, Portugal
|
| 2005 | Bolsa de Doutoramento
Fundação para a Ciência e a Tecnologia, Portugal
|