Marta Sousa Silva (F61E-BD62-1579)

Curriculum Vitae

Marta Sousa Silva

Marta Sousa Silva concluiu o Doutoramento em Biologia - Biologia Molecular em 2003/09 pela Universidade de Lisboa - Faculdade de Ciências. É Investigadora Principal Contratada na Faculdade de Ciências da Universidade de Lisboa. Estabeleceu a Unidade de Metabolómica no Laboratório de FTICR e Espectrometria de Massa Estrutural, baseada na ultra-alta resolução e exatidão de massa por espectrometria de massa de FTICR. Este laboratório está associado à Rede Nacional de Espectrometria de Massa (RNEM) e providencia tecnologia avançada e serviços inovadores na área das ciências aplicadas, fundamentais e à indústria. É ainda co-PI do centro Português no European Network of Fourier-Transform Ion-Cyclotron Resonance Mass Spectrometry Centres (INFRAIA H2020, proj. 731077) e membro do Steering Committee da Rede nacional de Espectrometria de Massa (RNEM). Desde 2018, é membro do Grupo de Peritos Nacionais de Viticultura e de Métodos de Análise da Comissão Nacional da Organização Internacional da Vinha e do Vinho (CNOIV), e membro da COVID-19 Mass Spectrometry Coalition desde 2020. ............................................................................................................................................... Marta Sousa Silva completed her PhD in Biology - Molecular Biology in 2003/09 at the University of Lisbon - Faculty of Sciences. She is a Contract Principal Investigator at the Faculty of Sciences of the University of Lisbon. Established the Metabolomics Unit in the Laboratory of FTICR and Structural Mass Spectrometry, based on the ultra-high resolution and mass accuracy of FTICR mass spectrometry. This laboratory is associated with the Portuguese Mass Spectrometry Network (RNEM) and provides advanced technology and innovative services in the area of applied and fundamental sciences and to industry. He is also co-PI of the Portuguese center at the European Network of Fourier-Transform Ion-Cyclotron Resonance Mass Spectrometry Centers (INFRAIA H2020, proj. 731077) and member of the Steering Committee of the National Mass Spectrometry Network (RNEM). Since 2018, he has been a member of the Group of National Experts on Viticulture and Methods of Analysis of the National Commission of the International Organization of Vine and Wine (CNOIV), and a member of the COVID-19 Mass Spectrometry Coalition since 2020.

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Identification

Personal identification

Full name: Marta Sousa Silva

Citation names

Sousa Silva, Marta
Silva, M. S.
Silva, Marta Sousa

Author identifiers

Ciência ID: F61E-BD62-1579
ORCID iD: 0000-0002-3080-9682
Scopus Author Id: 14066637300

Websites

http://ft-icr.rd.ciencias.ulisboa.pt/ (Professional)
https://ciencias.ulisboa.pt/pt/perfil/mfsilva (Scholar)

Knowledge fields

Natural sciences - Biological Sciences - Biochemistry
Agrarian Sciences - Agriculture, Forestry and Fisheries - Viticulture
Engineering and Technology - Environmental Biotechnology

Languages

Language	Speaking	Reading	Writing	Listening
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Intermediate (B1)	Advanced (C1)	Intermediate (B1)	Intermediate (B1)
Spanish; Castilian	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2003/09 Concluded	Doutoramento em Biologia - Biologia Molecular (Doutoramento) Universidade de Lisboa Faculdade de Ciências, Portugal "Expression of Mitogen-Activated Protein Kinases during Morphogenic Processes in Plants" (THESIS/DISSERTATION)	Approved with honour and distinction
1997/07 Concluded	Biologia Vegetal Aplicada (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal "Estudos do genes da via das MAPK no processo de embriogénese somática directa de Camellia japonica L. cv. Elegans" (THESIS/DISSERTATION)	16

Affiliation

Science

	Category Host institution	Employer
2019/05/01 - 2022/12/31	Contracted Researcher (Research)	Universidade de Lisboa Faculdade de Ciências, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal
2009 - 2013	Auxiliary Researcher (Research)	Universidade de Lisboa Centro de Química e Bioquímica, Portugal

2000/01/01 - 2003/12/31	Researcher (Research)	Universidade de Lisboa Faculdade de Ciências, Portugal

2000/09/01 - 2002/05/31	Researcher (Research)	Centro de Investigaciones Biológicas, Spain

Teaching in Higher Education

	Category Host institution	Employer
2023/01/01 - Current	Assistant Professor (University Teacher)	Universidade de Lisboa Faculdade de Ciências, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal
2014/08/01 - 2017/09/11	Invited Assistant Professor (University Teacher)	Universidade de Lisboa Faculdade de Ciências, Portugal

2015 - 2016	Invited Assistant Professor (University Teacher)	Universidade de Lisboa Centro de Química e Bioquímica, Portugal

2014 - 2016	Assistant Professor (University Teacher)	Universidade de Lisboa Faculdade de Ciências, Portugal

2013 - 2014	Invited Assistant Professor (University Teacher)	Universidade de Lisboa Faculdade de Ciências, Portugal

Others

	Category Host institution	Employer
2017/09/12 - 2018/12/31	Gestora de Ciência e Tecnologia	Universidade de Lisboa Faculdade de Ciências, Portugal

2014/08/01 - 2016/10/30	Cientista Convidado (bolsa de Projecto Europeu)	Universidade de Lisboa Faculdade de Ciências, Portugal

2009/07/01 - 2014/06/30	Research (Assistant Researcher from Program Ciência 2008, FCT)	Universidade de Lisboa Faculdade de Ciências, Portugal

2012/02/13 - 2014/01/31	Member of Executive Direction of Centro de Química e Bioquímica	Universidade de Lisboa Faculdade de Ciências, Portugal

2004/01/01 - 2009/06/30	Post-doc researcher	Universidade de Lisboa Faculdade de Ciências, Portugal

1998/01/01 - 2003/07/31	Ph.D. student	Universidade de Lisboa Faculdade de Ciências, Portugal

1995/01/01 - 2000/12/31	Research training	Universidade de Lisboa Faculdade de Ciências, Portugal

1997/04/01 - 1997/08/31	Research training	Université Paris-Sud Faculté des Sciences d'Orsay, France

Projects

Contract

	Designation	Funders
2023/02/01 - Current	Fragment-Screen - From fragments to high affinity binders interfacing integrated structural biology, medicinal chemistry and artificial inteligence grant agreement Nr 101094131 Researcher Universidade de Lisboa Faculdade de Ciências, Portugal	European Union Ongoing
2019/01/21 - Current	Bridging Ethnic Food Cultures through Chemistry 2017-037-2-300 Researcher	International Union of Pure and Applied Chemistry Ongoing
2018/10 - Current	Markers of Resistance in Grapevine: Correlating Metabolome Changes with Mildew Resistance PTDC/BAA-MOL/28675/2017 Principal investigator	Fundação para a Ciência e a Tecnologia Ongoing
2017/01 - Current	Rede Nacional de Espectrometria de Massa LISBOA-01-0145-FEDER-402-022125 Science and Technology Management Fellow	Fundação para a Ciência e Tecnologia (FCT)
2023/02 - 2026/01	CellNET: The role of phosphoinositides and NET actin-binding proteins in the regulation of vesicle traffic and secretion in plant cells Provided by PTCRIS: 2022.06990.PTDC 2022.06990.PTDC FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2023/12/31	YEASTYPE - Wine yeasts typing: discrimination of non-conventional wine yeasts through untargeted chemical fingerprinting EXPL/BTA-BTA/1389/2021 Principal investigator FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2022/07 - 2023/01	Methods for data augmentation in FT-ICR-MS untargeted metabolomics CPCA/A0/467905/2021	Fundação para a Ciência e a Tecnologia
2018/01 - 2022/06/30	European Network of Fourier-Transform Ion-Cyclotron-Resonance Mass Spectrometry Centers grant.731077 Researcher	European Commission Ongoing
2018/10/01 - 2021/09/30	A imunidade em videira: o papel inovador dos proteases serínicos do tipo subtilases PTDC/BIA-BQM/28539/2017 Instituto Nacional de Investigação Agrária e Veterinária, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/10/01 - 2021/09/30	OPTOX - Development and validation of bio-optical ecotoxicological tests in marine phototrophs. PTDC/CTA-AMB/30056/2017 Instituto de Engenharia de Sistemas e Computadores Inovação, Portugal Centro de Ciências do Mar e do Ambiente, Portugal Universidade de Lisboa Instituto de Geografia e Ordenamento do Território, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2020/07/01 - 2021/04/30	SAFE Coating - anti viral coating for wide spread use Research 4 COVID-19-SafeCoating Researcher Universidade de Lisboa Faculdade de Ciências, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2019/01/01 - 2019/12/31	Centro de Química e Bioquímica UID/Multi/00612/2019 FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2014/12 - 2016/12	Healthy life and active ageing – the contribute of functional food ingredients IUPAC 2013-054-2-300 Researcher	International Union of Pure and Applied Chemistry Ongoing
2013/11 - 2016/10	PERsonalised ICT Supported Service for Independent Living and Active Ageing grant.610359 Invited Scientist Fellow	European Commission Concluded
2013/07 - 2016/06	The architecture of life: Probing the quaternary structure of virus capsids by native mass spectrometry 125109 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2014/03 - 2015/02	Metabolic markers of downy mildew resistance in grapevine 133461 Principal investigator	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2012/01 - 2014/12	Unravelling grapevine defense mechanism against downy mildew through O`mics (transcriptomics, metabolomics and proteomics) networking 119753 Provided by PTCRIS: 119753 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2011/04 - 2014/12	Pathways proteomics in Leishmania: Mapping the functional proteome towards novel therapeutic opportunities 115178 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2010/11 - 2014/04	Acquisition of iron in Leishmania infantum - which are the players and what is their relevance for pathogenesis? 100090 Researcher	Fundação para a Ciência e a Tecnologia, I.P.
2011/01/01 - 2012/12/31	Strategic Project - UI 612 - 2011-2012 PEst-OE/QUI/UI0612/2011 Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008/01 - 2011/12	Protein glycation and transthyretin amyloidogenesis in yeast: A model system of neurodegenerative amyloid diseases 70610 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2007/01 - 2009/12	Ovothiol metabolism in Leishmania: Identification of new therapeutic targets 82478 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2005/10/01 - 2007/06/30	Metabolismo do ovotiol em Leishmania: Identificação de novos alvos terapêuticos POCI/QUI/62027/2004 Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Centro de Química e Bioquímica, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005/10 - 2007/06	Ovothiol metabolism in Leishmania: Identification of new therapeutic targets 62027 Researcher	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2004/01 - 2006/12	The glyoxalase pathway in Leishmania: potential therapeutic applications POCTI/ESP/48272/2002 Research Fellow	Fundação para a Ciência e a Tecnologia, I.P. Concluded
1996/09 - 1997/08	Studies of MAPK genes during somatic embryogenesis of Camellia japonica AMICA - Project of Technological Priority - PTP154 Principal investigator	Directorate-General for Research and Innovation Concluded

Outputs

Publications

Book chapter	Ferreira, António E.N.; Sousa Silva, Marta; Cordeiro, Carlos. "Metabolic Network Inference from Time Series". In Systems Medicine, 127-133. Elsevier, 2021. 10.1016/b978-0-12-801238-3.11347-9 Piedade, Claudio Alexandre; Sousa Silva, Marta; Cordeiro, Carlos; E. N. Ferreira, António. "Virus Disassembly Pathways Predicted from Geometry and Configuration Energy". In Communications in Computer and Information Science, 289-301. Springer International Publishing, 2018. Published • 10.1007/978-3-319-94806-5_16 O’Caoimh, Rónán; Molloy, D. William; Fitzgerald, Carol; Van Velsen, Lex; Cabrita, Miriam; Nassabi, Mohammad Hossein; de Vette, Frederiek; et al. "ICT-Supported Interventions Targeting Pre-frailty: Healthcare Recommendations from the Personalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) Study". In Information and Communication Technologies for Ageing Well and e-Health, 69-92. Springer International Publishing, 2018. 10.1007/978-3-319-93644-4_4 Silva, Marta Sousa; Ferreira, António E. N.; Gomes, Ricardo; Tomás, Ana M.; Freire, Ana Ponces; Cordeiro, Carlos. "Glyoxalase Enzymes in Trypanosomatids". In Trypanosomatid Diseases, 153-166. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. 10.1002/9783527670383.ch8
Conference abstract	dos Santos, Ivo; Jaime A. Ramos; Pais De Faria, Joana; Jorge M. Pereira; Cerveira, Lara; Laranjeiro, Maria I.; Almeida, Nathalie; et al. Corresponding author: dos Santos, Ivo. "Yellow-legged gull (Larus michahellis) as a bioindicator of trace elements and organic contaminants along a gradient of exposure". Paper presented in XI Congresso de Ornitologia da SPEA, Ponta Delgada, 2023. Published Mariana Vieira Pereira; Nelson G. M. Gomes; Cordeiro, Carlos; Madureira-Carvalho, Áurea; Silva, Marta Sousa. "Uncovering the invisible world of fingerprints by FT-ICR-MS". Paper presented in Congress 2022 APCF-TOXRUN, Porto, 2022. Published • 10.51126/revsalus.v4isup.449 Cavaco AR; Maia, Marisa; Laureano, Gonçalo; Duarte, Bernardo; Caçador; Isabel; Silva, Marta Sousa; Matos, Ana Rita; Figueiredo, Andreia. "Identifying grapevine lipid biomarkers of resistance/susceptibility to Plasmopara viticola; towards a sustainable viticulture". Paper presented in 19th SFRRI Biennal Meeting, Lisboa, 2018. Published Duarte, Bernardo; Cordeiro, Carlos; Sousa Silva, Marta; Figueiredo, Andreia; Rosa, Rui; Canário, João; Caçador, Isabel; et al. "Hg-Planktarctic - Unravelling the metabolic adaptations in phytoplankton continuously exposed to volcanic-mercury in Deception Island waters (Antarctica)". 2018. Published • 10.3389/conf.fmars.2018.06.00033
Conference paper	Rónán O'Caoimh; D. William Molloy; Carol Fitzgerald; Lex Van Velsen; Miriam Cabrita; Mohammad Hossein Nassabi; Frederiek de Vette; et al. "Healthcare Recommendations from the Personalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) Study". 2017. 10.5220/0006331800910103 Piedade, Claudio Alexandre; Ferreira, António E. N.; Cordeiro, Carlos. "How to Disassemble a Virus Capsid - A Computational Approach". Paper presented in 10th International Joint Conference on Biomedical Engineering Systems and Technologies, 2016. 10.5220/0006249802170222 Abecasis, JPR; Ferreira, AEN; Vicente Miranda, Hugo; Gomes, Ricardo Anjos; Sousa Silva, Marta; Cordeiro, Carlos; Ponces-Freire, Ana. "Parameter estimation in multi-enzyme systems using evolutionary algorithms". Paper presented in BKDB2005 ¿ Bioinformatics: Knowledge Discovery in Biology, 2005. Published • 10.13140/RG.2.1.1468.8802
Conference poster	Louro, Mariana; Silva, Marta Sousa; Cordeiro, Carlos. "Deciphering the complexity of SARS-CoV-2 infection by FT-ICR-MS". Paper presented in Ciências Research and Innovation Day, 2023. Luz, João; Traquete, Francisco; Ferreira, António; Sousa Silva, Marta; Cordeiro, Carlos. "Towards a score-based metabolite identification algorithm for extreme resolution mass spectrometry". Paper presented in 3rd Chem&Biochem Students Meeting, 2023. Cruz, Marta; Louro, Mariana; Silva, Marta Sousa; Cordeiro, Carlos; Maria Romão. "Fingermarks: The new standard for clinical metabolomics?". Paper presented in 3rd Chem & Biochem Students Meeting, 2023. Louro, Mariana; Silva, Marta Sousa; Cordeiro, Carlos. "Unraveling the metabolome and lipidome of SARS-CoV-2 infection by FT-ICR-MS". Paper presented in 3rd Chem&Biochem Students Meeting, 2023. Traquete, Francisco; Sousa Silva, Marta; Ferreira, António. "Addressing Metabolomics Data Analysis Challenges: GAN-based approach for metabolomics data augmentation to counteract low sample number, friend or foe?". Paper presented in Metabolomics 2023 (19th International Conference of the Metabolomics Society), 2023. Cordeiro, Carlos; Madureira-Carvalho, Áurea; Gomes, Nelson; Pereira, Mariana; Cruz, Marta; Matthias Witt; Silva, Marta Sousa. "Hidden in plain sight: Fingermark metabolomics revealed by MRMS". Paper presented in IMMS 2023, 2023. Traquete, Francisco; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Ferreira, António. "Spectral feature occurrence as a viable alternative to intensity-based data for profiling and discrimination in untargeted metabolomics". Paper presented in 2nd Chem & BiochemStudents Meeting, 2022. Luz, João; Pendão, Ana Sofia; Traquete, Francisco; Ferreira, António; Sousa Silva, Marta; Cordeiro, Carlos. "A metabolomics approach to the study of the effects of single-gene deletions in yeast". Paper presented in 2nd Chem & BiochemStudents Meeting, 2022. Osawa, Rodrigo; Louro, Mariana; Soeiro, Mónica; Luz, João; Traquete, Francisco; Marques, Ana; Ferreira, António; Sousa Silva, Marta; Cordeiro, Carlos. "From Grapevine to the dinning table: unprecedented approach using FT-ICR-MS". Paper presented in 14th European Fourier Transform Mass Spectrometry Workshop & 3rd EFTMS School, 2022. Pereira, Mariana; Luz, João; Gomes, Nelson; Cordeiro, Carlos; Madureira-Carvalho, Áurea; Sousa Silva, Marta. "Revealing the Chemical Universe of Fingermarks by FT-ICR-MS". Paper presented in 2nd Chem & Biochem Students Meeting, 2022. Pereira, Mariana; Luz, João; Nelson G. M. Gomes; Cordeiro, Carlos; Madureira-Carvalho, Áurea; Silva, Marta Sousa. "Revealing the Chemical World of Fingermarks Through FT ICR MS". Paper presented in 14th European Fourier Transform Mass Spectrometry Workshop, 2022. Luz, João; Pendão, Ana Sofia; Traquete, Francisco; Ferreira, António; Sousa Silva, Marta; Cordeiro, Carlos. "FT-ICR-MS uncovers large-scale metabolic differences between phenotypically identical yeasts". Paper presented in 14th European Fourier Transform Mass Spectrometry Workshop & 3rd EFTMS School, 2022. Traquete, Francisco; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Ferreira, António. "Using Graph Properties of Mass-Difference Networks for Profiling and Discrimination in Untargeted Metabolomics". Paper presented in 14th European Fourier Transform Mass Spectrometry Workshop & 3rd EFTMS School, 2022. Traquete, Francisco; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Ferreira, António. "Spectral feature occurrence as a complementary approach to intensity-based data for profiling and discrimination in untargeted metabolomics". Paper presented in Metabolomics 2022 (18th International Conference of the Metabolomics Society), 2022. Luz, João; Pendão, Ana Sofia; Traquete, Francisco; Ferreira, António; Sousa Silva, Marta; Cordeiro, Carlos. "Metabolomic effects of single-gene deletions in Saccharomyces cerevisae". Paper presented in X-Omics Festival 2021, 2021. Traquete, Francisco; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Ferreira, António. "Binary Similarity Measures as an Effective Tool in Metabolomics Data Analysis". Paper presented in X-Omics Festival 2021, 2021. Duarte, I.A.; Reis-Santos, P.; Cabral, H.N.; Duarte, Bernardo; Rato, Lénia; Novais, Sara; Lemos, M.F.L.; et al. "Long-term effects of exposure to pharmaceuticals in a top predator fish.". Paper presented in CHEERS 2019, 2019. Laureano, Gonçalo; Figueiredo, J.; Cavaco AR; Duarte, Bernardo; Caçador; Isabel; Malhó, Rui; Silva, Marta Sousa; Matos, Ana Rita; Figueiredo, Andreia. "Lipid signalling role in the search for sustainable approaches to control grapevine fungal diseases". Paper presented in Seminário Internacional Alimentação, Saúde e Ambiente: Sustentabilidade e Desafios, 2018. Nascimento, Rui; Maia, Marisa; Ferreira, A. E. N.; Marques, A.P.; Freire, Ana Ponces; Cordeiro, Carlos; Silva, Marta Sousa; Figueiredo, Andreia. "Metabolic profile of V. vinifera cv. Trincadeira upon Plasmopara viticola infection". Paper presented in Encontro Ciência 2018, 2018. Maia, M.; Höfle, Rebecca; Cavaco AR; Ferreira, A; Cordeiro, C; Töpfer, Reinhard; Kircherer, Anna; Figueiredo, Andreia; Sousa Silva, Marta. "Combining metabolomics and phenotyping to discover biomarkers of resistance to downy mildew". 2018. 10.1016/j.freeradbiomed.2018.04.433 Maia, Marisa; Höfle, Rebecca; Cavaco AR; Laureano, Gonçalo; Figueiredo, J.; Ferreira, António; Cordeiro, Carlos; et al. "Grapevine resistance to Plasmopara viticola: the search for metabolic biomarkers". Paper presented in XII International conference on grapevine breeding and genetics, 2018. Cavaco AR; Maia, Marisa; Laureano, Gonçalo; Duarte, Bernardo; Silva, Marta Sousa; Matos, Ana Rita; Figueiredo, Andreia. "Grapevine phenotyping in resistance/susceptibility to Plasmopara viticola". Paper presented in Plant phenotyping for future climate challenges (COSTFA1306), 2018. Maia, Marisa; Figueiredo, Andreia; Sousa Silva, Marta. "The quest for grapevine resistance associated compounds: metabolomics as a promising approach". Paper presented in Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal, 2018. Laureano, G.; Figueiredo, J.; Cavaco AR; Duarte, Bernardo; Caçador, I.; Malhó, R.; Sousa Silva, M.; et al. "Lipid signalling role in the search for sustainable approaches in grapevine fungal diseases". Paper presented in Seminário Internacional - Alimentação Saúde e Ambiente: Sustentabilidade e Desafios, 2018. Nascimento, Rui; Maia, Marisa; Silva, Marta Sousa; Figueiredo, Andreia; Cordeiro, Carlos; Ferreira, António E.N.. "Metabolinks: tools for high-resolution MS metabolomics data analysis". Paper presented in 5th Portuguese Mass Spectrometry Meeting (PTMS2017), 2017. Nascimento, Rui; Maia, Marisa; Ferreira, António E.N.; Marques, A.P.; Cordeiro, Carlos; Silva, Marta Sousa; Figueiredo, Andreia. "Metabolic characterization of V. vinifera cv. Trincadeira in Plasmopara viticola infected leaves". Paper presented in 5th Portuguese Mass Spectrometry Meeting (PTMS2017), 2017. Nascimento, Rui; Figueiredo, Andreia; Figueiredo, Joana; Maia, Marisa; Laureano, Gonçalo; Cavaco, Ana Rita; da Silva, Clemente; et al. "Grapevine-downy mildew resistance mechanisms uncovered by a multi-¿Omics approach". Paper presented in 5th Portuguese Mass Spectrometry Meeting (PTMS2017), 2017. da Silva, Clemente; Figueiredo, J.; Laureano, Gonçalo; Silva, Marta Sousa; Figueiredo, Andreia. "Expression of subtilases involved in grapevine resistance to Plasmopara viticola". Paper presented in CQB Day, 31st May, 2017. Nascimento, Rui; Maia, Marisa; Ferreira, António E.N.; Marques, A.P.; Freire, Ana Ponces; Cordeiro, Carlos; Silva, Marta Sousa; Figueiredo, Andreia. "Metabolic characterization of V. vinifera cv. Trincadeira upon Plasmopara viticola infection". Paper presented in CQB DAY 2017, Faculdade de Ciências da Universidade de Lisboa, 2017. Nascimento, Rui; Maia, Marisa; Ferreira, A. E. N.; Marques, A.P.; Figueiredo, Joana; Freire, Ana Ponces; Cordeiro, Carlos; Figueiredo, Andreia; Sousa Silva, Marta. "Grapevine leaves metabolic characterization for a resistance biomarker discovery". Paper presented in CQB DAY 2017 (pp 50), Faculdade de Ciências da Universidade de Lisboa, 2017. Fortes, A. M.; Santos, F.; Figueiredo, A.; Choi, Y.H.; Silva, M. S.; Acioli, B.; Sebastiana, M.; et al. "Transcriptional and metabolic profiling during organogenic nodule formation in hop.". Paper presented in 5th PlantGem´s, 2006. Fortes, A. M.; Santos, F.; Figueiredo, A.; Acioli, B.; Sousa, L.; Sebastiana, M.; Silva, M. S.; et al. "Transcriptional profiling during organogenic nodule formation in hop.". Paper presented in 3rd EPSO CONFERENCE ¿Plant Dynamics: from Molecules to Ecosystems¿, 2006.
Edited book	Sousa Silva, Marta; Roessner, Ute; Cordeiro, Carlos. Corresponding author: Sousa Silva, Marta. Metabolomics in crop research – current and emerging methodologies, volume II. Lausanne, Switzerland: Frontiers Media SA. 2023. Published • 10.3389/978-2-8325-3646-9 • Editor Sousa Silva, Marta; Figueiredo, Andreia (881D-86E5-D52A); Roessner, ute; Cordeiro, Carlos. Metabolomics in Crop Research – Current and Emerging Methodologies. Lausanne, Switzerland: Frontiers Media SA. 2019. Published • 10.3389/978-2-88963-158-2 • Editor
Journal article	Marta Sousa Silva; Mónica Soeiro; Carlos Cordeiro. "From the grapevine to the glass: A wine metabolomics tale by FT-ICR-MS". Journal of Mass Spectrometry (2024): https://doi.org/10.1002/jms.5019. 10.1002/jms.5019 Ana M Santos; Ana Soares; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Teresa Dias; Juliana Melo; Cristina Cruz ; Luis Carvalho. Corresponding author: Cristina Cruz. "Microbial interactions as a sustainable tool for enhancing PGPR antagonism against phytopathogenic fungi". Sustainability 16 5 (2024): 2006. https://www.mdpi.com/2071-1050/16/5/2006. Open access • Published • 10.3390/su16052006 Sousa Silva, Marta; Roessner, Ute; Cordeiro, Carlos. "Editorial: Metabolomics in crop research – current and emerging methodologies, volume II". Frontiers in Plant Science 14 (2023): http://dx.doi.org/10.3389/fpls.2023.1292878. 10.3389/fpls.2023.1292878 Nogues, Isabel; Passatore, Laura; Bustamante, María Ángeles; Pallozzi, Emanuele; Luz, João; Traquete, Francisco; Ferreira, António E. N.; Sousa Silva, Marta; Cordeiro, Carlos. "Cultivation of Melilotus officinalis as a source of bioactive compounds in association with soil recovery practices". Frontiers in Plant Science 14 (2023): http://dx.doi.org/10.3389/fpls.2023.1218594. 10.3389/fpls.2023.1218594 Bernardo Duarte; Eduardo Feijão; Ricardo Cruz de Carvalho; Irina A. Duarte; Ana Patrícia Marques; Marisa Maia; Jasmine Hertzog; et al. "Untargeted Metabolomics Reveals Antidepressant Effects in a Marine Photosynthetic Organism: The Diatom Phaeodactylum tricornutum as a Case Study". Biology 11 12 (2022): 1770-1770. http://dx.doi.org/10.3390/biology11121770. 10.3390/biology11121770 Maia, Marisa; McCann, Andréa; Malherbe, Cédric; Far, Johann; Cunha, Jorge; Eiras-Dias, José; Cordeiro, Carlos; et al. "Grapevine leaf MALDI-MS imaging reveals the localisation of a putatively identified sucrose metabolite associated to Plasmopara viticola development". Frontiers in Plant Science 13 (2022): http://dx.doi.org/10.3389/fpls.2022.1012636. 10.3389/fpls.2022.1012636 Pinto, Daniela; Gonçalo, Raquel; Louro, Mariana; Silva, Marta Sousa; Hernandez, Guillem; Cordeiro, Tiago N.; Cordeiro, Carlos; São-José, Carlos. "On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes". Microbiology Spectrum 10 4 (2022): http://dx.doi.org/10.1128/spectrum.01037-22. 10.1128/spectrum.01037-22 Traquete, Francisco; Luz, João; Cordeiro, Carlos; Sousa Silva, Marta; Ferreira, António E. N.. "Graph Properties of Mass-Difference Networks for Profiling and Discrimination in Untargeted Metabolomics". Frontiers in Molecular Biosciences 9 (2022): http://dx.doi.org/10.3389/fmolb.2022.917911. Published • 10.3389/fmolb.2022.917911 Francisco Traquete; João Luz; Carlos Cordeiro; Marta Sousa Silva; António E. N. Ferreira. "Binary Simplification as an Effective Tool in Metabolomics Data Analysis". Metabolites (2021): https://doi.org/10.3390/metabo11110788. 10.3390/metabo11110788 Sousa Silva, Marta. "FT-ICR-MS-based metabolomics: A deep dive into plant metabolism". Mass Spectrometry Reviews (2021): http://dx.doi.org/10.1002/mas.21731. 10.1002/mas.21731 Bernardo Duarte; Carla Gameiro; Ana Rita Matos; Andreia Figueiredo; Marta Sousa Silva; Carlos Cordeiro; Isabel Caçador; et al. "First screening of biocides, persistent organic pollutants, pharmaceutical and personal care products in Antarctic phytoplankton from Deception Island by FT-ICR-MS". Chemosphere 274 (2021): 129860-129860. https://doi.org/10.1016%2Fj.chemosphere.2021.129860. 10.1016/j.chemosphere.2021.129860 M. Sebastiana; A. Gargallo-Garriga; J. Sardans; M. Pérez-Trujillo; F. Monteiro; A. Figueiredo; M. Maia; et al. "Metabolomics and transcriptomics to decipher molecular mechanisms underlying ectomycorrhizal root colonization of an oak tree". Scientific Reports (2021): 10.1038/s41598-021-87886-5 Marisa Maia; António E.N. Ferreira; Jorge Cunha; José Eiras-Dias; Carlos Cordeiro; Andreia Figueiredo; Marta Sousa Silva. "Comparison of the chemical diversity of Vitis rotundifolia and Vitis vinifera cv. ‘Cabernet Sauvignon’". Ciência e Técnica Vitivinícola 36 1 (2021): 1-8. https://doi.org/10.1051%2Fctv%2F20213601001. 10.1051/ctv/20213601001 Cinzia Ingallina; Alessandro Maccelli; Mattia Spano; Giacomo Di Matteo; Antonella Di Sotto; Anna Maria Giusti; Giuliana Vinci; et al. "Chemico-Biological Characterization of Torpedino Di Fondi® Tomato Fruits: A Comparison with San Marzano Cultivar at Two Ripeness Stages". Antioxidants 9 10 (2020): 1027-1027. https://doi.org/10.3390%2Fantiox9101027. 10.3390/antiox9101027 Maia, Marisa; Ferreira, António E. N.; Nascimento, Rui; Monteiro, Filipa; Traquete, Francisco; Marques, Ana P.; Cunha, Jorge; et al. "Integrating metabolomics and targeted gene expression to uncover potential biomarkers of fungal/oomycetes-associated disease susceptibility in grapevine". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-72781-2. 10.1038/s41598-020-72781-2 Sousa Silva, Marta. "Pathogen-related specificity of subtilase VVISBT4.19 X1 in the Vitis vinifera defence response". Ciência e Técnica Vitivinícola (2020): http://dx.doi.org/10.1051/ctv/20203501042. 10.1051/ctv/20203501042 Sousa Silva, Marta. "An apoplastic fluid extraction method for the characterization of grapevine leaves proteome and metabolome from a single sample". Physiologia Plantarum (2020): http://dx.doi.org/10.1111/ppl.13198. 10.1111/ppl.13198 Laureano, Gonçalo; Figueiredo, J.; Cavaco AR; Duarte, Bernardo; Caçador, Isabel; Malhó, Rui; Silva, Marta Sousa; Matos, Ana Rita; Figueiredo, Andreia. "Author Correction: The interplay between membrane lipids and phospholipase A family members in grapevine resistance against Plasmopara viticola". Scientific Reports (2019): https://doi.org/10.1038/s41598-019-42135-8. 10.1038/s41598-019-42135-8 Marta Sousa Silva; Carlos Cordeiro; Ute Roessner; Andreia Figueiredo. "Editorial: Metabolomics in Crop Research—Current and Emerging Methodologies". Frontiers in Plant Science 10 (2019): https://doi.org/10.3389%2Ffpls.2019.01013. 10.3389/fpls.2019.01013 A.R. Cavaco; J. Figueiredo; G. Laureano; M. Sousa Silva; A.R. Matos; A. Figueiredo. "Subtilisin-like proteins and lipid signalling events: the missing links in grapevine resistance to Plasmopara viticola". Acta Horticulturae 1248 (2019): 567-574. https://doi.org/10.17660%2Factahortic.2019.1248.76. 10.17660/actahortic.2019.1248.76 M. Maia; A. Maccelli; R. Nascimento; A.E.N. Ferreira; M.E. Crestoni; C. Cordeiro; A. Figueiredo; M. Sousa Silva. "Early detection of Plasmopara viticola-infected leaves through FT-ICR-MS metabolic profiling". Acta Horticulturae 1248 (2019): 575-580. https://doi.org/10.17660%2Factahortic.2019.1248.77. 10.17660/actahortic.2019.1248.77 Rui Nascimento; Marisa Maia; António E.N. Ferreira; Anabela B. Silva; Ana Ponces Freire; Carlos Cordeiro; Marta Sousa Silva; Andreia Figueiredo. "Early stage metabolic events associated with the establishment of Vitis vinifera – Plasmopara viticola compatible interaction". Plant Physiology and Biochemistry 137 (2019): 1-13. https://doi.org/10.1016%2Fj.plaphy.2019.01.026. 10.1016/j.plaphy.2019.01.026 Silva, Marta; Figueiredo,Andreia; Figueiredo,Joana; Maia,Marisa; Cavaco,Ana Rita; Laureano,Gonçalo; Nascimento,Rui; et al. "Subtilisin-like proteases and lipid signalling events play an important role in grapevine resistance to downy mildew: a systems biology approach". Revista de Ciências Agrárias (2019): http://www.scielo.mec.pt/scielo.php?script=sci_arttext&pid=S0871-018X2018000500010. 10.19084/RCA17325 Silva, Marta; Maia,Marisa; Ferreira,António E. N.; Marques,Ana P.; Figueiredo,Joana; Freire,Ana Ponces; Cordeiro,Carlos; Figueiredo,Andreia; Silva,Marta Sousa. "Uncovering markers for mildew resistance in grapevine through mass spectrometry-based metabolomics". Revista de Ciências Agrárias (2019): http://www.scielo.mec.pt/scielo.php?script=sci_arttext&pid=S0871-018X2018000500008. 10.19084/RCA17334 Silva, Marta. "Assessing the link between subtilases and lipid signaling events in grapevine downy mildew resistance". Revista de Ciências Agrárias (2019): 10.19084/RCA17330 Marisa Maia; António E. N. Ferreira; Gonçalo Laureano; Ana Patrícia Marques; Vukosava M. Torres; Anabela Bernardes Silva; Ana Rita Matos; et al. "Vitis vinifera ‘Pinot noir’ leaves as a source of bioactive nutraceutical compounds". Food & Function 10 7 (2019): 3822-3827. https://doi.org/10.1039/C8FO02328J. 10.1039/C8FO02328J Figueiredo, Andreia; Figueiredo, J.; Maia, Marisa; Cavaco AR; Laureano, Gonçalo; Nascimento, Rui; Da Silva, Clemente; Matos, Ana Rita; Silva, Marta Sousa. "Grapevine-downy mildew resistance strategies: towards a sustainable viticulture". Revista de Ciências Agrárias / Impact factor 0.9 41 special (2019): 61-66. https://doi.org/10.19084/rca.17068. Published Laureano G; Figueiredo J; Cavaco AR; Duarte B; Caçador I; Malhó R; Sousa Silva M; et al. "The interplay between membrane lipids and phospholipase A family members in grapevine resistance against Plasmopara viticola.". Scientific reports (2018): http://europepmc.org/abstract/med/30266912. 10.1038/s41598-018-32559-z Joana Figueiredo; Clemente da Silva; André Folgado; Rita Abranches; Marta Sousa Silva; Andreia Figueiredo. "Production and biochemical characterization of grapevine subtilase associated to Plasmopara viticola resistance". Free Radical Biology and Medicine 120 (2018): S132-S132. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.434. 10.1016/j.freeradbiomed.2018.04.434 Figueiredo,Joana; Laureano,Gonçalo; Silva,Clemente da; Maia,Marisa; Silva,Marta Sousa; Figueiredo,Andreia. "Accessing the link between subtilases and lipid signalling events in grapevine downy mildew resistance". (2018): http://www.scielo.mec.pt/scielo.php?script=sci_arttext&pid=S0871-018X2018000500009. Joana Figueiredo; Marisa Maia; Marta Sousa Silva; Andreia Figueiredo. "Grapevine Subtilase Family: Update on New Sequences and Nomenclature Proposal". Frontiers in Plant Science 8 (2017): https://doi.org/10.3389%2Ffpls.2017.00716. 10.3389/fpls.2017.00716 Joana Figueiredo; Marta Sousa Silva; Andreia Figueiredo. "Subtilisin-like proteases in plant defence: The past, the present and beyond". Molecular Plant Pathology (2017): https://doi.org/10.1111%2Fmpp.12567. 10.1111/mpp.12567 Marisa Maia; Filipa Monteiro; Mónica Sebastiana; Ana Patrícia Marques; António E.N. Ferreira; Ana Ponces Freire; Carlos Cordeiro; Andreia Figueiredo; Marta Sousa Silva. "Metabolite extraction for high-throughput FTICR-MS-based metabolomics of grapevine leaves". EuPA Open Proteomics 12 (2016): 4-9. http://dx.doi.org/10.1016/j.euprot.2016.03.002. 10.1016/j.euprot.2016.03.002 Ana Guerreiro; Joana Figueiredo; Marta Sousa Silva; Andreia Figueiredo. "Linking Jasmonic Acid to Grapevine Resistance against the Biotrophic Oomycete Plasmopara viticola". Front. Plant Sci. 7 (2016): http://dx.doi.org/10.3389/fpls.2016.00565. 10.3389/fpls.2016.00565 Figueiredo J; Costa GJ; Maia M; Paulo OS; Malhó R; Sousa Silva M; Figueiredo A. "Revisiting Vitis vinifera Subtilase Gene Family: A Possible Role in Grapevine Resistance against Plasmopara viticola.". (2016): http://europepmc.org/abstract/med/27933087. Marques AP; Serralheiro ML; Ferreira AE; Freire AP; Cordeiro C; Silva MS. "Metabolomics for undergraduates: Identification and pathway assignment of mitochondrial metabolites.". (2015): http://europepmc.org/abstract/med/26537432. 10.1002/bmb.20919 Sousa Silva, M.; Gomes, R.A.; Ferreira, A.E.N.; Ponces Freire, A.; Cordeiro, C.. "The glyoxalase pathway: The first hundred years... and beyond". Biochemical Journal 453 1 (2013): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879026126&partnerID=MN8TOARS. 10.1042/BJ20121743 Martins, A.; Santos, M.S.; Dias, C.; Serra, P.; Cachatra, V.; Pais, J.; Caio, J.; et al. "Tuning the bioactivity of tensioactive deoxy glycosides to structure: Antibacterial activity versus selective cholinesterase inhibition rationalized by molecular docking". European Journal of Organic Chemistry 8 (2013): 1448-1459. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874904689&partnerID=MN8TOARS. 10.1002/ejoc.201201520 Rivaldi, J.D.; Sousa Silva, M.L.C.; Duarte, L.C.; Ferreira, A.E.N.; Cordeiro, C.; De Almeida Felipe, M.D.G.; De Ponces Freire, A.; De Mancilha, I.M.. "Metabolism of biodiesel-derived glycerol in probiotic Lactobacillus strains". Applied Microbiology and Biotechnology 97 4 (2013): 1735-1743. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874358825&partnerID=MN8TOARS. 10.1007/s00253-012-4621-z Carlos Cordeiro; Marta Sousa Silva. "A Espectrometria de Massa na World Wide Web". Boletim da Sociedade Portuguesa de Química (2012): 60-60. https://doi.org/10.52590%2Fm3.p654.a30001723. 10.52590/m3.p654.a30001723 Gomes, R.A.; Franco, C.; Da Costa, G.; Planchon, S.; Renaut, J.; Ribeiro, R.M.; Pinto, F.; et al. "The Proteome Response to Amyloid Protein Expression In Vivo". PLoS ONE 7 11 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84869850066&partnerID=MN8TOARS. 10.1371/journal.pone.0050123 Sousa Silva, M.; Ferreira, A.E.N.; Gomes, R.; Tomás, A.M.; Ponces Freire, A.; Cordeiro, C.. "The glyoxalase pathway in protozoan parasites". International Journal of Medical Microbiology 302 4-5 (2012): 225-229. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866632897&partnerID=MN8TOARS. 10.1016/j.ijmm.2012.07.005 Falé, P.L.; Amaral, F.; Amorim Madeira, P.J.; Sousa Silva, M.; Florêncio, M.H.; Frazão, F.N.; Serralheiro, M.L.M.. "Acetylcholinesterase inhibition, antioxidant activity and toxicity of Peumus boldus water extracts on HeLa and Caco-2 cell lines". Food and Chemical Toxicology 50 8 (2012): 2656-2662. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864067234&partnerID=MN8TOARS. 10.1016/j.fct.2012.04.049 Lages, N.F.; Cordeiro, C.; Sousa Silva, M.; Ponces Freire, A.; Ferreira, A.E.N.. "Optimization of time-course experiments for kinetic model discrimination". PLoS ONE 7 3 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84857723721&partnerID=MN8TOARS. 10.1371/journal.pone.0032749 Barata, L.; Sousa Silva, M.; Schuldt, L.; Ferreira, A.E.N.; Gomes, R.A.; Tomás, A.M.; Weiss, M.S.; Ponces Freire, A.; Cordeiro, C.. "Enlightening the molecular basis of trypanothione specificity in trypanosomatids: Mutagenesis of Leishmania infantum glyoxalase II". Experimental Parasitology 129 4 (2011): 402-408. http://www.scopus.com/inward/record.url?eid=2-s2.0-80455122647&partnerID=MN8TOARS. 10.1016/j.exppara.2011.08.008 Fortes, A.M.; Agudelo-Romero, P.; Silva, M.S.; Ali, K.; Sousa, L.; Maltese, F.; Choi, Y.H.; et al. "Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening". BMC Plant Biology 11 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-80055110827&partnerID=MN8TOARS. 10.1186/1471-2229-11-149 Barata, L.; Sousa Silva, M.; Schuldt, L.; Da Costa, G.; Tomás, A.M.; Ferreira, A.E.N.; Weiss, M.S.; Ponces Freire, A.; Cordeiro, C.. "Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of glyoxalase i from Leishmania infantum". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 66 5 (2010): 571-574. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951993959&partnerID=MN8TOARS. 10.1107/S1744309110010754 Gomes, R.A.; Oliveira, L.M.A.; Silva, M.; Ascenso, C.; Quintas, A.; Costa, G.; Coelho, A.V.; et al. "Protein glycation in vivo: Functional and structural effects on yeast enolase". Biochemical Journal 416 3 (2008): 317-325. http://www.scopus.com/inward/record.url?eid=2-s2.0-58949095221&partnerID=MN8TOARS. 10.1042/BJ20080632 Fortes, A.M.; Santos, F.; Choi, Y.H.; Silva, M.S.; Figueiredo, A.; Sousa, L.; Pessoa, F.; et al. "Organogenic nodule development in hop (Humulus lupulus L.): Transcript and metabolic responses". BMC Genomics 9 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-54949090034&partnerID=MN8TOARS. 10.1186/1471-2164-9-445 Ispolnov, K.; Gomes, R.A.; Silva, M.S.; Freire, A.P.. "Extracellular methylglyoxal toxicity in Saccharomyces cerevisiae: Role of glucose and phosphate ions". Journal of Applied Microbiology 104 4 (2008): 1092-1102. http://www.scopus.com/inward/record.url?eid=2-s2.0-40849104959&partnerID=MN8TOARS. 10.1111/j.1365-2672.2007.03641.x Gomes, R.A.; Miranda, H.V.; Sousa Silva, M.; Graça, G.; Coelho, A.V.; Do Nascimento Ferreira, A.E.; Cordeiro, C.; Freire, A.P.. "Protein glycation and methylglyoxal metabolism in yeast: Finding peptide needles in protein haystacks". FEMS Yeast Research 8 1 (2008): 174-181. http://www.scopus.com/inward/record.url?eid=2-s2.0-38349156416&partnerID=MN8TOARS. 10.1111/j.1567-1364.2007.00337.x Silva, M.S.; Barata, L.; Ferreira, A.E.N.; Romão, S.; Tomás, A.M.; Freire, A.P.; Cordeiro, C.. "Catalysis and structural properties of Leishmania infantum glyoxalase II: Trypanothione specificity and phylogeny". Biochemistry 47 1 (2008): 195-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-37849007277&partnerID=MN8TOARS. 10.1021/bi700989m Nuno Lages; Marta Silva; António EN Ferreira; Ana Tomás; Carlos Cordeiro; Ana Freire. "Potential role of the glyoxalase pathway as a drug target in Leishmania infantum: an exact steady-state model analysis". BMC Syst Biol 1 Suppl 1 (2007): S8-S8. http://dx.doi.org/10.1186/1752-0509-1-s1-s8. 10.1186/1752-0509-1-s1-s8 Gomes, R.A.; Miranda, H.V.; Silva, M.S.; Graça, G.; Coelho, A.V.; Ferreira, A.E.; Cordeiro, C.; Freire, A.P.. "Yeast protein glycation in vivo by methylglyoxal: Molecular modification of glycolytic enzymes and heat shock proteins". FEBS Journal 273 23 (2006): 5273-5287. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751095900&partnerID=MN8TOARS. 10.1111/j.1742-4658.2006.05520.x Barata, L.; Sousa Silva, M.; Trincão, J.; Carvalho, S.; Ferreira, A.E.N.; Bonifácio, C.; Cordeiro, C.; et al. "Purification, crystallization and preliminary X-ray diffraction analysis of the glyoxalase II from Leishmania infantum". Acta Crystallographica Section F: Structural Biology and Crystallization Communications 62 8 (2006): 805-807. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747177058&partnerID=MN8TOARS. 10.1107/S1744309106027539 Ana M Fortes; Marta Silva; Joana Costa; Maria Coronado; Pilar S Testillano; Maria Risueco; Maria S Pais. "Organogenic nodule formation from hop internodes. Reactive oxygen species and expression of lipoxygenase and extracellular-regulated kinases". BMC Plant Biol 5 Suppl 1 (2005): S16-S16. http://dx.doi.org/10.1186/1471-2229-5-s1-s16. 10.1186/1471-2229-5-s1-s16 Gomes, R.A.; Silva, M.S.; Miranda, H.V.; Ferreira, A.E.N.; Cordeiro, C.A.A.; Freire, A.P.. "Protein glycation in Saccharomyces cerevisiae: Argpyrimidine formation and methylglyoxal catabolism". FEBS Journal 272 17 (2005): 4521-4531. http://www.scopus.com/inward/record.url?eid=2-s2.0-24644494767&partnerID=MN8TOARS. 10.1111/j.1742-4658.2005.04872.x Silva, M.S.; Ferreira, A.E.N.; Tomás, A.M.; Cordeiro, C.; Freire, A.P.. "Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation". FEBS Journal 272 10 (2005): 2388-2398. http://www.scopus.com/inward/record.url?eid=2-s2.0-18944383472&partnerID=MN8TOARS. 10.1111/j.1742-4658.2005.04632.x Gomes, R.; Sousa Silva, M.; Quintas, A.; Cordeiro, C.; Freire, A.; Pereira, P.; Martins, A.; et al. "Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy". Biochemical Journal 385 2 (2005): 339-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-19944432234&partnerID=MN8TOARS. 10.1042/BJ20040833 Sousa Silva, M.; Fortes, A.M.; Testillano, P.S.; Risueño, M.delC.; Pais, M.S.. "Differential expression and cellular localization of ERKs during organogenic nodule formation from internodes of Humulus lupulus var. Nugget". European Journal of Cell Biology 83 8 (2004): 425-433. http://www.scopus.com/inward/record.url?eid=2-s2.0-4744370473&partnerID=MN8TOARS. 10.1078/0171-9335-00397
Newsletter article	Cruz, Marta; Sousa Silva, Marta; Pereira, Mariana; Nelson G. M. Gomes; Madureira-Carvalho, Áurea; Cordeiro, Carlos. "The invisible metabolic world of fingermarks revealed by Magnetic Resonance Mass Spectrometry (MRMS)", Bruker Application Note, 2023 Sousa Silva, Marta; Luz, João; Pendão, Ana Sofia; Cordeiro, Carlos. "Magnetic Resonance Mass Spectrometry (MRMS) discriminates yeast mutants through metabolomics", MRMS 75 - Metabolomics of Yeast Mutants, 2021, https://www.bruker.com/en/products-and-solutions/mass-spectrometry/mrms.html. Sousa Silva, Marta; Cordeiro, Carlos. "Mass spectrometry-based metabolomics in grapevine and wine fingerprinting", Science and Wine blog, 2019, https://www.ciencia-e-vinho.com/2019/10/13/mass-spectrometry-based-metabolomics-in-grapevine-and-wine-fingerprinting/.
Preprint	Isabel Nogues; Laura Passatore; María Ángeles Bustamante; Emanuele Pallozzi; João Luz; Francisco Traquete; António E.N. Ferreira; Marta Sousa Silva; Carlos Cordeiro. "Cultivation ofMelilotus officinalisas a source of bioactive compounds in association with soil recovery practices". 2023. https://doi.org/10.1101/2023.04.24.538143. 10.1101/2023.04.24.538143 Maia M; McCann A; Malherbe C; Far J; Cunha J; Eiras-Dias J; Cordeiro C; et al. "Grapevine leaf MALDI-MS imaging reveals the localisation of a putatively identified sucrose metabolite associated to Plasmopara viticola development". 2022. http://europepmc.org/abstract/PPR/PPR525934. 10.1101/2022.08.01.502001
Report	Rauter, Amélia P.; Turkman, Maria Antónia; Turkman, Feridun; Antunes, Marília; Silva, Marta Sousa; Ferreira, António; Martins, Alice; et al. 2015. PERSSILAA D3.1 - Screening methods and anticipatory triage protocol. http://perssilaa.rrdweb.nl/. Hermens, Hermie; Vollenbroek-Hutten, Miriam; Nassabi, Mohammad Hossein; Rauter, Amélia P.; Turkman, Antónia; Turkman, Feridun; Antunes, Marília; et al. 2014. PERSSILAA D6.2 - Dissemination Plan. http://perssilaa.rrdweb.nl/.
Thesis / Dissertation	Cavaco, Ana Rita Sebastião Mendes; Silva, Marta Sousa; Cordeiro, Carlos, 1966-. "Sintase do óxido nítrico de Leishmania infantum: da sequência à estrutura". Master, 2015. http://hdl.handle.net/10451/22439.
Website	Sousa Silva, Marta. FT-ICR-MS-Lisboa. 2018. http://ft-icr.rd.ciencias.ulisboa.pt/. Sousa Silva, Marta. Lisbon Centre of Mass Spectrometry and Proteomics. 2015. http://lcms-proteomics.fc.ul.pt/. Sousa Silva, Marta. NUTRIAGEING. 2014. http://nutriageing.fc.ul.pt/index.html.

Other

Other output

Plant-pathogen interaction in modern agriculture: grapevine as a case study. Poster presented at the 4th Annual Conference -- Foster Innovation through Resilient and Efficient Agro Food \& Forestry Systems -- redeAGRO. 2017. Figueiredo, A.; Maia, M.; Nascimento, R.; Laureano, G.; Figueiredo, J.; Silva, C.; Matos, A. R.; et al.

Activities

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023/01/01 - Current	Unravelling differential immune responses to SARS-CoV-2 infection through metabolomics and proteomics - bolsa FCT Maria de Sousa Co-supervisor	Doutoramento em Bioquímica (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2023/01/01 - Current	Metabolomics-guided design of synthetic microbial communities: Towards a clean and sustainable agriculture Co-supervisor of João Mendonça da Luz	Bioquímica (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2022/03/01 - Current	New mass spectrometry methods against biological warfare threats Co-supervisor	Bioquímica (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2021/10/01 - 2023/04/17	The invisible world of fingerprints revealed by mass spectrometry Supervisor	Química (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2020/09/01 - 2022/03/18	The assembly of protein complexes in vivo: pathways and stability Co-supervisor of Mariana Louro	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2021/09/14	Pathways of resistance in Grapevine: mapping the functional proteome and metabolome towards mildew resistance Supervisor of Marisa Raquel Gomes Maia	Bioquímica (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2021	Marker assisted selection for grapevine breeding: subtilisin-like proteases as strong candidates linked to immune priming Co-supervisor of Joana Frazão Figueiredo	Bioquímica (PhD) Universidade de Lisboa Faculdade de Ciências, Portugal
2019/09/01 - 2020/12/31	Metabolomic effects of single gene deletions in Saccharomyces cerevisiae Supervisor of João Luz	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2019/09/01 - 2020/12/31	Top-down proteomics: Protein glycation by methylglyoxal in yeast Co-supervisor of Ana Sofia Pendão	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2019/09/01 - 2020/12/31	Binary Similarity Measures and Mass-Difference Network Analysis as Effective Tools in Metabolomics Data Analysis Co-supervisor of Francisco Traquete	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2019/09/01 - 2020/12/31	Analysis of protein complexes in vivo by native mass spectrometry Co-supervisor of Margarida Isidro	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017	Characterization of metabolic pathways involved in the compatible interaction between Vitis vinifera and Plasmopara viticola Supervisor of Rui Francisco Costa Marcos do Nascimento	Biologia Molecular e Genética (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017	Characterization and expression of subtilases involved in grapevine resistance to Plasmopara viticola Co-supervisor of Clemente da Silva	Biologia Molecular e Genética (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2017	Metabolism of non-conventional wine yeasts Supervisor of Alexandra Sofia Baptista Lança	Microbiologia Aplicada (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2016	Revisiting Vitis vinifera subtilase gene family: links to grapevine resistance against Plasmopara viticola Co-supervisor of Joana Frazão Figueiredo	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2016	Metabolic characterization of grapevine leaves: first clues towards biomarkers discovery Supervisor of Marisa Raquel Gomes Maia	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2015	Sintase do óxido nítrico de Leishmania infantum: da sequência à estrutura Supervisor of Ana Rita Sebastião Mendes Cavaco	Bioquímica (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2006 - 2006	Metabolismo do Metilglioxal em Tripanossomatídeos Co-supervisor of Lídia Isabel Sebastião Barata	Bioquímica (PhD) Universidade de Lisboa, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2019/04/14 - 2019/04/18	EU FT-ICR MS - Advanced Users School 1 - a School for Advanced-Users community: people involved in FT MS either using Orbitrap or ICR detection (2019/04/14 - 2019/04/18) Other (Co-organisor)	Universidade de Lisboa Faculdade de Ciências, Portugal
2017/09/20 - 2017/09/22	5th Portuguese Mass Spectrometry Meeting (PTMS2017) (2017/04/20 - 2017/04/22) Conference (Co-organisor)	Universidade de Lisboa Faculdade de Ciências, Portugal
2016/12/19 - 2016/12/21	Top Down and Structural Mass Spectrometry: a practical course (2016/12/19 - 2016/12/21) Other (Co-organisor)	Universidade de Lisboa Faculdade de Ciências, Portugal

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2015/10/07	Entrevista / comentário sobre o Prémio Nobel da Química 2015 para a descoberta dos mecanismos de reparação do DNA.	Observador

Interview (tv / radio show)

	Program	Topic
2020/09/10 - 2020/09/10	90 Segundos de Ciência (Antena 1)	Ep. 914 Marta Sousa Silva – Estudo quer encontrar biomarcadores associados à resistência da videira ao míldio

Distinctions

Award

2022	Prémio “Distinção CNOIV Viticultura” Instituto da Vinha e do Vinho IP, Portugal
2022	Prémio “Inovação CNOIV” Instituto da Vinha e do Vinho IP, Portugal

Other distinction

2017	Projet Omics2Clinic: Assay for diagnosis of Parkinsons Disease (by V.M. Torres, D. Penque e M. Sousa Silva) was in the finals of ScienceIN2Business 2017 Universidade de Lisboa Faculdade de Ciências, Portugal
2015	Prémio de Melhor Apresentação Oral - "NUTRIAGEING: combining science, cooking and agriculture" Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2010	COST Action CM0801 - Awarded fellowship European Cooperation in Science and Technology, Belgium
2004	National Institutes of Health - Awarded fellowship National Institutes of Health, United States
1997	PTP Research Training - Awarded fellowship John Innes Centre, United Kingdom