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Késsia Hapuque Santos de Andrade.
Identification

Personal identification

Full name
Késsia Hapuque Santos de Andrade
Date of birth
1995/03/30
Gender
Female

Citation names

  • Andrade, Késsia

Author identifiers

Ciência ID
F714-AC95-979B
ORCID iD
0000-0003-3374-0294

Telephones

Mobile phone
  • 927682163 (Personal)

Addresses

  • Rua Dr. Jaime Cortesão, nº16, RC A, 2620-146, Póvoa de Santo Adrião, Odivelas, Portugal (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Portuguese (Mother tongue)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2019/11/01 - 2023/10
Ongoing
 Doutoramento em Farmácia (Doutoramento)
Major in Química Farmacêutica e Terapêutica
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/09 - 2018/11/12
Concluded
 Química Bioorgânica (Mestrado integrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Cyclopentenones: synthesis and biological evaluation in human cancer cells" (THESIS/DISSERTATION)
 17
2013/09 - 2016/06/20
Concluded
 Bioquímica (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Optimização e Validação de um Método de Quantificação de Melatonina por Cromatografia Líquida de Alta Eficiência acoplado a um Detector de Florescência" (THESIS/DISSERTATION)
 14
Affiliation

Others

Category
Host institution 		Employer
2017/09/01 - 2018/11/01 Research in the field of Medicinal Chemistry. Master Thesis: "Cyclopentenones: Synthesis and biological evaluation in human cancer cells", i.Med Group. Advisor: Prof. Dr. Carlos A. M. Afonso; Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/07/01 - 2017/02/01 Research in the field of "Quantification of melatonin present in the Choroid Plexus of Rattus Norvegicus by HPLC-FLD as potential biomarker of Alzheimer's Disease"Prof. Dr. Marco Silva Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Projects

Grant

Designation Funders
2019/03/11 - 2019/10/31 Abordagem bio orgânica na valorização de águas residuais da indústria alimentar: Caso da lupanina
WaterJPI/0001/2014
Research Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Andrade, Késsia. "Photocatalytic oxidation of Thiazolidines to Thiazolines". Paper presented in 14th iMed.ULisboa Postgraduate Students Meeting, Lisboa, Portugal, 2023.
  2. Andrade, Késsia. "Synthetic valorization of olive leaf crude extract promoted by organocatalysts". Paper presented in Chemical Science symposium 2022: Sustainable synthesis and catalysis, Royal Society of Chemistry, London, UK, 2022.
  3. Andrade, Késsia. "Development of bio renewable chemical building block from olive leaves". Paper presented in 13th iMed.ULisboa Postgraduate Students Meeting, Lisboa, Portugal, 2022.
  4. Esteves, Teresa; Flávio A. Ferreira; Ana T. Mota; Barbeitos, Catarina; Andrade, Késsia; Carlos A.M. Afonso; Frederico C. Ferreira. Corresponding author: Esteves, Teresa. "A molecular imprinting polymer (MIP) for the isolation of lupanine coupled to nanofiltration and solvent extraction". Paper presented in Affinity 2021, 2021.
  5. Andrade, Késsia. "Methanolysis reaction promoted by organocatalysts". Paper presented in 12th iMed.ULisboa Postgraduate Students Meeting, Lisboa, Portugal, 2021.
  6. Andrade, Késsia. "Synthesis and biological evaluation of cyclopentenones in human cancer cells". Paper presented in 4th Meeting of the CQUL (4ECQUL) and Summer School – “Chemistry: Shaping the future, Lisboa, Portugal, 2019.
  7. Andrade, Késsia. "Cyclopentenones as new anticancer agents: synthesis and biological evaluation,". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, Lisbon, Portugal, 2019.
  8. Andrade, Késsia. "Synthesis and anti-proliferative activity evaluation in human cancer cells of cyclopentenone derivatives". Paper presented in Chemistry @ULisboa & 2018 Summer School, 3º Encontro “A Química na Investigação” da ULisboa (3ECQUL), Lisboa, Portugal, 2018.
  9. Andrade, Késsia. "Synthesis of a cyclopentenone family and evaluation of their anti-proliferative activity in human cancer cells". Paper presented in 6th Portuguese Young Chemists Meeting (6th PYCheM); Setúbal, Portugal., 2018.
  10. Andrade, Késsia. "Preparation and biological evaluation of a cyclopentenone family as anticancer agents: Structure Activity Relationship and mechanism of action". Paper presented in 12th National Organic Chemistry Meeting (12ENQO) and the 5th National Medicinal Chemistry Meeting (5ENQT), Coimbra, Portugal., 2018.
Journal article
  1. Rafael F. A. Gomes; Bruno M. F. Gonçalves; Késsia H. S. Andrade; Bárbara B. Sousa; Nuno Maulide; Gonçalo J. L. Bernardes; Carlos A. M. Afonso. "Unlocking the Potential of Bio-Based Nitrogen-Rich Furanic Platforms as Biomass Synthons". Angewandte Chemie International Edition (2023): http://dx.doi.org/10.1002/anie.202304449.
    10.1002/anie.202304449
  2. João R. Vale; Milene A. G. Fortunato; Késsia H. S. Andrade; Ângelo M. R. Rocha; Carlos Alberto Mateus Afonso; Filipa Siopa. "From Pyridine to (-)-Agelastatin A". Advanced Synthesis & Catalysis (2023): http://dx.doi.org/10.1002/adsc.202300560.
    10.1002/adsc.202300560
  3. Késsia H. S. Andrade; Jaime A. S. Coelho; Raquel Frade; Ana M. Madureira; João P. M. Nunes; Stephen Caddick; Rafael Gomes; Carlos A. M. Afonso. "Functionalized Cyclopentenones with Low Electrophilic Character as Anticancer Agents". ChemMedChem (2023): http://dx.doi.org/10.1002/cmdc.202300104.
    10.1002/cmdc.202300104
  4. Késsia H. S. Andrade; Jaime A. S. Coelho; Raquel Frade; Ana M. Madureira; João P. M. Nunes; Stephen Caddick; Rafael Gome. "Front Cover: Functionalized Cyclopentenones with Low Electrophilic Character as Anticancer Agents (ChemMedChem 13/2023)". ChemMedChem 18 13 (2023): https://doi.org/10.1002/cmdc.202300303.
  5. "Greener Strategy for Lupanine Purification from Lupin Bean Wastewaters Using a Molecularly Imprinted Polymer.". ACS applied materials & interfaces (2022): https://doi.org/10.1021/acsami.2c02053.
    10.1021/acsami.2c02053
  6. "Tandem Thio-Michael Addition/Remote Lactone Activation of 5-Hydroxymethylfurfural-Derived d-Lactone-Fused Cyclopentenones.". ChemSusChem (2022): https://doi.org/10.1002/cssc.202102204.
    10.1002/cssc.202102204
  7. "Functionalized cyclopentenones and oxime ether as antimicrobial agents". ChemMedChem (2021): http://dx.doi.org/10.1002/cmdc.202100369.
    10.1002/cmdc.202100369
  8. "A study on lupin beans process wastewater nanofiltration treatment and lupanine recovery". Journal of Cleaner Production 277 (2020): 123349-123349. http://dx.doi.org/10.1016/j.jclepro.2020.123349.
    10.1016/j.jclepro.2020.123349
  9. "Choroid plexus is an additional source of melatonin in the brain". Journal of Pineal Research (2018): http://dx.doi.org/10.1111/jpi.12528.
    10.1111/jpi.12528
Preprint
  1. Carlos Alberto Mateus Afonso; João Rafael Vale; Milene Fortunato; Késsia Andrade; Filipa Siopa. "Combining photochemical transformation of pyridinium salt with kinetic enzymatic resolution towards the total synthesis of (-)-agelastatin A". 2022. http://dx.doi.org/10.26434/chemrxiv-2022-314m3.
    10.26434/chemrxiv-2022-314m3
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01 Photocatalytic oxidation of bio-based heterocyclic compounds 15th National Organic Chemistry Meeting (15º ENQO) & 8th National Medicinal Chemistry Meeting (8º ENQT)
(Faro, Portugal)
2023/09 Photocatalytic oxidation of biomass-derived heterocycles International Symposium of Synthesis and Catalysis (ISYSYCAT)
(Évora, Portugal)
2023/02 Synthetic valorization of Olive Leaves Crude Extract Winter School on Photosynthesis and Photocatalysis and Workshop on Biomass Valorization
(Sofia, Bulgaria)
2022 Synthetic valorization of olive leaf crude extract via methanolysis reaction under batch conditions 14th National Organic Chemistry Meeting (14º ENQO) & 7th National Medicinal Chemistry Meeting (7º ENQT)
(Caparican(Setubal), Portugal)
2022 Synthetic valorisation of olive leaves by acid catalyzed methanolysis of phenolic compounds as Oleuropein 5th Meeting of the CQUL (5ECQUL) and Summer School – “Forging Bonds”
Reitoria Universidade de Lisboa (Lisboa, Portugal)
2021/08 Valorization of olive leaf crude extract via methanolysis reaction promoted by organosylated and organosulfonic catalysts International Symposium of Synthesis and Catalysis, ISYSYCAT
Universidade de Évora (Évora, Portugal)
2018/02 Preparation and biological evaluation of a cyclopentenone family as anticancer agents: Structure Activity Relationship and mechanism of action 7ª Edição das Jornadas Intercalares dos Mestrados do DQ e do DCV
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (Caparica, Setúbal, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/07 - 2018/07 NMR Workshop in Medicinal Chemistry, Faculty of Sciences and Technologies - NOVA University of Lisbon, Caparica, Portugal
Seminar
 NMR Workshop in Medicinal Chemistry
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 - 2018/07 Poster communication: "Cyclopentanones Derivatives as Anti-Cancer Agents: Preparation and Biological Evaluation" 10th Meeting of Postgraduate Students- i.Med ULisboa and 3rd Meeting i3DU, Lisbon, Portugal
Meeting
 10th Meeting of Postgraduate Students- i.Med ULisboa and 3rd Meeting i3DU
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/05 - 2018/05 Seminar "Challenges in Chemical Synthesis: Flow Chemistry and NMR Spectroscopy", Faculty of Pharmacy - University of Lisbon, Lisbon, Portugal
Seminar
 Challenges in Chemical Synthesis: Flow Chemistry and NMR Spectroscopy
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/02 - 2016/02 Jornadas Tecnológicas de Bioquímica da Faculdade de Ciências e Tecnologia -Universidade Nova de Lisboa (JORTEC)
Other
 Jornadas Tecnológicas de Bioquímica da Faculdade de Ciências e Tecnologia
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/02 - 2015/02 Jornadas Tecnológicas de Bioquímica da Faculdade de Ciências e Tecnologia -Universidade Nova de Lisboa (JORTEC)
Other
 Jornadas Tecnológicas de Bioquímica da Faculdade de Ciências e Tecnologia
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/03 - 2014/03 VII National Meeting of Students of Biochemistry (ENEBIOQ), NOVA University of Lisbon, Caparica, Portugal
Meeting
 VII National Meeting of Students of Biochemistry (ENEBIOQ)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/03 - 2014/03 Workshop of Crystallography, NOVA University of Lisbon, Caparica, Portugal
Workshop
 Workshop of Crystallography
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/02 - 2014/02 Jornadas Tecnológicas de Bioquímica da Faculdade de Ciências e Tecnologia -Universidade Nova de Lisboa (JORTEC)
Other
 Technology Days of Biochemistry (JORTEC)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal