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Paulo Jorge Cardoso da Costa was born in Porto, Portugal, in 1963. He graduated in Pharmaceutical Sciences (Pharm. D) in 1989 (Industrial Pharmacy - option B), graduated in Pharmaceutical Sciences (Pharm. D) in 1992 (Community and Hospital Pharmacy - option A) and obtained its Ph.D in Pharmaceutical Technology at the Faculty of Pharmacy, University of Porto in 1999, with a thesis named "Solid Pharmaceutical Forms, Comparative Study of Drug Release Kinetics". He is an Associate Professor with habilitation of the Department of Drug Sciences, Laboratory of Pharmaceutical Technology, of the Faculty of Pharmacy of the University of Porto, since April 2021. He teaches several curricular units in the area of production and control of medicines and other health products in several study cycles by the Faculty of Pharmacy of the University of Porto, namely the Integrated Master's degree in Pharmaceutical Sciences (MICF), the Master's degree in Pharmaceutical Technology (MTF) and the Master's degree in Quality Control (MCQ). He develops research activities in the area of modified drug release, nanotechnology, cutaneous formulations and evaluation of their quality, safety and efficacy (among others) integrated in the MEDTECH Research Lab (Pharmaceutical Technology) involved in the thematic line "Diagnostics, drug discovery and development" of UCIBIO-Requimte (UCIBIO - Applied Molecular Biosciences Unit). Guides or co-directs research work in various cycles of study. He is the author or co-author of several publications in scientific journals in the pharmaceutical area (more than 100 articles published in indexed journals and more than 9000 citations , h-index 38; Scopus Author ID: 7201895686; Orcid ID: 0000-0002-1152-3398; ResearcherID: G-2820-2011). He is listed as "World's Top 2% Scientists 2023" – "Career-long data are updated to end-of-2022" (56727 rank) and "single recent year data refer to citations received during the calendar year 2022" (37503 rank). He is the Director of the Master's Degree in Pharmaceutical Technology since April 2019. He has been a Member of the Scientific Council of the Faculty of Pharmacy of the University of Porto since January 2016. He was a Member of the U.Porto Scientific and Editorial Council since November 2016 until October 2020. He is the President of the Board of Representatives of the Faculty of Pharmacy of the University of Porto since December 2018. He has been a Member of the Senate of the University of Porto since December 2018. He is the head of the Pharmaceutical Technology Laboratory of the Faculty of Pharmacy of the University of Porto since October 2021.
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Identification

Personal identification

Full name
Paulo Jorge Cardoso da Costa

Citation names

  • Costa, Paulo

Author identifiers

Ciência ID
F917-0147-AA0C
ORCID iD
0000-0002-1152-3398
Researcher Id
G-2820-2011
Scopus Author Id
7201895686

Email addresses

  • pccosta@ff.up.pt (Professional)

Addresses

  • Faculdade de Farmácia da Universidade do Porto, Rua de Jorge Viterbo Ferreira nº. 228, 4050-313 P, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2021/07/28
Concluded
 Agregação em Ciências Farmacêuticas (Título de Agregado) (Outros)
Major in Tecnologia Farmacêutica
Universidade do Porto Faculdade de Farmácia, Portugal
 Aprovado por unanimidade
1999/07/29
Concluded
 Ciências Farmacêuticas (Doutoramento)
Major in Tecnologia Farmacêutica
Universidade do Porto Faculdade de Farmácia, Portugal
1990 - 1992
Concluded
 Ciências Farmacêuticas (Licenciatura)
Major in Opção A (Farmácia de Oficina e Hospitalar)
Universidade do Porto Faculdade de Farmácia, Portugal
 15
1983 - 1989
Concluded
 Ciências Farmacêuticas (Licenciatura)
Major in Opção B (Farmácia Industrial)
Universidade do Porto Faculdade de Farmácia, Portugal
 15
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2006/04/27 - Current Associate Professor (University Teacher) Universidade do Porto, Portugal
1999/07 - 2006/04 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Positions / Appointments

Category
Host institution 		Employer
2016 - 2018 Conselho científico/técnico-científico ou orgão correspondente Universidade do Porto, Portugal
Projects

Grant

Designation Funders
2011/07 - 2014/06 InVitroBrain - Development of a humanized dynamic in vitro blood-brain barrier model and a vesicle-based barrier for brain penetration of drugs incorporated in lipid nanoparticles - Closing the gap between in vivo and in vitro properties
112277
Provided by PTCRIS: 112277
PTDC/SAU-FAR/112277/2009
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2021/01/01 - 2025/12/31 Instituto para a Saúde e a Bioeconomia
LA/P/0140/2020
10.54499/LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/02/01 - 2024/07/31 Uma nova tecnologia para mitigar a exposição ocupacional dos bombeiros a compostos orgânicos persistentes: desenvolvimento de uma pastilha elástica, aplicação in vivo, e avaliação de risco in vitro
2022.05381.PTDC
10.54499/2022.05381.PTDC
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Unidade de Ciências Biomoleculares Aplicadas
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/01/01 - 2023/12/31 Unidade de Ciências Biomoleculares Aplicadas
UIDP/04378/2020
10.54499/UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Applied Molecular Biosciences Unit
UID/Multi/04378/2019
Universidade do Porto Faculdade de Ciências, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/06/01 - 2019/06/01 Navigating through marine-derived fungi: bioprospection and synthesis of bioactive secondary metabolites and analogues as chemotherapic agents
PTDC/MAR-BIO/4694/2014
Provided by PTCRIS: 143327
POCI-01-0145-FEDER-016790
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Fundação Ensino e Cultura Fernando Pessoa, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2018 Preparação e caracterização físico química de nanopartículas lipídicas como carreadores de triterpenos para o tratamento da Leishmaniose Visceral
18/04080-2
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2011/06 - 2015/05 Estudo dos factores psicossociais e tecnológicos que influenciam a adesão ao tratamento na psoríase
04-GCQF-CICS-2011
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2011/07 - 2014/06 InVitroBrain - Desenvolvimento de um modelo celular humano dinâmico da barreira hematoencefálica e de um modelo de membrana de liposomas para testar a passagem para o cérebro de fármacos incorporados em nanopartículas lipídicas. Correlações in vivo/in vitro
FCT PTDC/SAU-FAR/112277/2009
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2010/05 - 2013/11 Sistema híbrido injectável libertador de estrôncio para utilização em vertebroplastia
PTDC/CTM/103181/2008
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2008 - 2010 2ND DERMIS - Têxteis funcionais como forma de prevenção e controlo de doenças do foro imunológico
SI I&DT 2008/1448
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2007 - 2010 Tecnologia de microencapsulação adaptada para bactérias probióticas: produção e melhoramento da estabilidade em diferentes vectores
PTDC/AGR-ALI/71051/2006
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2007 - 2010 Desenvolvimento galénico de novos produtos dermocosméticos incorporados com água termal das termas de S. Pedro do Sul
NITEC Nº 71/00075
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2007 - 2010 PROBIOCAPS - Tecnologia de microencapsulação adaptada para bactérias probióticas: produção e melhoramento da estabilidade em diferentes vectores
PTDC/AGR-ALI/71051/2006
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2007 - 2008 Advanced control of pharmaceutical specialties with near-infrared spectroscopy and chemometrics
IPG2007-131
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2005 - 2008 Biodopa - Formas farmacêuticas contendo fármacos antiparkinsonianos
13-02-03-FDR-02037
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2003 - 2006 Sistema injectável de libertação de enzimas constituído por nanopartículas de apatite e microesferas de hidrogéis naturais para regeneração óssea
POCTI/41523/FCB/2001
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded

Other

Designation Funders
2007 - 2007 Essais Comparatifs: Antirides
CONTRAT Nº EC 2007-021
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2000 - 2000 Essais Comparatifs: Antirides
Contrato N°EC 2000-017
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
2000 - 2000 Essais Comparatifs: Shampooing Pour Cheveux Gras
Contrato N°EC 2000-033
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
1999 - 1999 Essais Comparatifs: Produits Amincissants
Contrato N°EC 1999-027
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
Concluded
Outputs

Publications

Book
  1. Amaral, M.H.; Sousa e Silva, J.P.; Costa, P.J.C.; Gomes, A.M.. Development of probiotic dosage forms. 2014.
Book chapter
  1. da Costa, P.J.C.; de Jesus, A.I.M.; de Almeida, I.F.M.. "Tissue-based in vitro and ex vivo models for dermal permeability studies". 479-500. 2024.
  2. Ana Camila Marques; Paulo Cardoso da Costa; Sérgia Velho; Maria Helena Amaral. "Antibody-Functionalized Nanoparticles for Targeted Drug Delivery in Cancer Therapy". 2023.
    10.1007/978-3-030-80962-1_297-1
  3. Silva, Ana Margarida; Luís, Ana Sofia; Macedo, Catarina; Ferreira, Ana Sofia; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Cosmetic applications of herbal products and encapsulated herbal active extracts". In Nanotechnology in Herbal Medicine - Applications and Innovations, edited by Thomas, Sabu; Oyedeji, Adebola Omowunmi; Oluwafemi, Oluwatobi Samuel; Jaquilin PJ, Rose, 447-490. Elsevier, 2023.
    Published
  4. Silva, Ana Margarida; Macedo, Catarina; Latocha, Piotr; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Valorization of Actinidia spp. by-products and wastes for nutraceutical applications". In Nutraceutics from agri-food by-products, edited by Spizzirri, Gianfranco, 69-116. Scrivener Publishing LLC in cooperation with John Wiley and Sons Ltd., 2023.
    Published
  5. Sousa, Filipa; Ferreira, Domingos; Reis, Salette; Costa, Paulo. "Is Micro and Nanotechnology Helping Us Fight Histoplasmosis?". In Histoplasmosis - A Comprehensive Study of Epidemiology, Pathogenesis, Diagnosis, and Treatment. United Kingdom: IntechOpen, 2023.
    Published • 10.5772/intechopen.110544
  6. Silva, A.M.; Luís, A.S.; Macedo, C.; Ferreira, A.S.; Costa, P.C.; Delerue-Matos, C.; Rodrigues, F.. "Cosmetic applications of herbal products and encapsulated herbal active extracts". 447-490. 2023.
  7. Teixeira, M.I.; Lopes, C.M.; Amaral, M.H.; Costa, P.C.. "Silver nanoparticles for the management of neurological diseases". 209-239. 2023.
  8. Silva, A.M.; Macedo, C.; Latocha, P.; Costa, P.; Delerue-Matos, C.; Rodrigues, F.. "Valorization of Actinidia spp. by-products and wastes for nutraceutical applications". 69-116. 2023.
  9. Pinto, D.; Braga, N.; Silva, A.M.; Costa, P.; Delerue-Matos, C.; Rodrigues, F.. "Chestnut". 127-144. 2020.
  10. Diana Pinto; Nair Braga,; Ana Margarida Silva; Costa, Paulo; Cristina Delerue-Matos; Francisca Rodrigues. "Chestnut". In Valorization of Fruit Processing By products, 127-144. Academic Press, 2019.
    Published
  11. Costa, Paulo; Isabel F. M. Almeida. "Tissue-based in vitro and ex vivo models for dermal permeability studies". 325-342. 2015.
    Published • 10.1016/B978-0-08-100094-6.00018-3
  12. Costa, Paulo. "Immobilization and microencapsulation of probiotics". 171-226. 2014.
    10.4032/9789814411639
  13. Amaral, Maria H.; Silva, J. Paulo Sousa; Costa, Paulo J. C.; Gomes, Ana M.. "Development of Probiotic Dosage Forms". edited by Silva, J. Paulo Sousa; Freitas, Ana C., 227-262. 2014.
  14. Costa, Paulo; Helena Amaral; Teófilo Vasconcelos. "Sistemas osmóticos". In Novas Formas Farmacêuticas Para Administração de Fármacos, 15-52. Portugal: Edições Universidade Fernando Pessoa, 2011.
    Published
  15. Carla M. Lopes; Costa, Paulo. "Sistemas matriciais". In Novas Formas Farmacêuticas Para Administração de Fármacos, 53-103. Portugal: Edições Universidade Fernando Pessoa, 2011.
    Published
Conference abstract
  1. Silva, Ana Margarida; Costa, Paulo; Delerue-Matos, Cristina; Rodrigues, Francisca. "Kiwiberry leaves extracts: A sustainable and promising cosmetic ingredient". Paper presented in Controlled Release Society 2021 Virtual Annual Meeting, 2021.
    Accepted
  2. Conceição, J.; Vieira, Cátia; Amorim, Andreia; Costa, Paulo; Sousa Lobo, J.M.. "Lubrication in tablet formulations: Polyethylene glycol 4000 and sodium lauryl sulphate". Paper presented in 2nd European Conference on Pharmaceutics - Novel dosage forms and innovative technologies, Cracóvia, 2017.
    Published
  3. Vieira, Cátia; Conceição, J.; Amorim, Andreia; Costa, Paulo; Sousa Lobo, J. M.. "Hydrophilic lubricants of tablets: Study of physics of compression and drug release characteristics". Paper presented in IJUP’17 - 10.º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2017.
    Published
  4. Amorim, Andreia; Conceição, J.; Vieira, Cátia; Simões, A. M.; Costa, Paulo; Sousa Lobo, J. M.. "Development and characterization of sustained release tablets". Paper presented in IJUP’17 - 10.º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2017.
    Published
  5. Rodrigues, Liliana; Conceição, J.; Vaz, Quitéria; Mesquita, Pedro; Costa, Paulo; Sousa Lobo, J. M.. "Preparation and technological characterization of hard gelatin capsules". Paper presented in IJUP’17 10.º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2017.
    Published
  6. Fonte, Sofia; Conceição, J.; Pedroso, Marta; Carneiro, Margarida; Costa, Paulo; Sousa Lobo, J. M.. "Preparation and technological characterization of hypromellose (HPMC) capsules". Paper presented in IJUP’17 - 10.º Encontro de Investigação Jovem da Universidade do Porto, Porto, 2017.
    Published
  7. Conceição, J.; Rocha, João; Bastos, Francisca; Pedroso, Marta; Carneiro, Margarida; Martins, Ana Cidália; Costa, Paulo; Sousa Lobo, J. M.. "Formulation and optimization of bilayer tablets". Paper presented in 11th Central European Symposium on Pharmaceutical Technology, Belgrado, 2016.
    Published
  8. Conceição, J.; Bastos, Francisca; Rocha, João; Costa, Paulo; Sousa Lobo, J.M.. "Bilayer tablets with carbamazepine as a biphasic quick/slow delivery system". Paper presented in 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, 2016.
    Published
  9. Rocha, João; Conceição, J.; Bastos, Francisca; Pedroso, Marta; Carneiro, Margarida; Martins, Ana Cidália; Ferreira, M.; Costa, Paulo; Sousa Lobo, J. M.. "Optimization studies on formulation of bilayer tablets with carbamazepine". Paper presented in IJUP’16 - 9.º Encontro de Jovens Investigadores da Universidade do Porto, Porto, 2016.
    Published
  10. Bastos, Francisca; Conceição, J.; Rocha, João; Costa, Paulo; Sousa Lobo, J. M.. "Development and characterization of bilayer tablets with carbamazepine". Paper presented in IJUP’16 - 9.º Encontro de Jovens Investigadores da Universidade do Porto, Porto, 2016.
    Published
  11. Ferreira, Marlene; Moreira, Gabriela; Azevedo, R. ; Marques, C.; Conceição, J.; Ferreira, Domingos Carvalho; Sousa Lobo, J. M. ; Costa, Paulo. "Development and characterization of lipid nanoparticles containing paclitaxel for glioma treatment". Paper presented in Development and characterization of lipid nanoparticles containing paclitaxel for glioma treatment, Porto, 2016.
    Published
  12. Conceição, J.; Fernandes, Sandra; Costa, Paulo; Sousa Lobo, J.M.. "Controlled release tablet formulations: Effect of hydrophilic matrix and fillers on active pharmaceutical ingredient release". Paper presented in 42nd Controlled Release Society (CRS) Annual Meeting and Exposition, Edimburgo, 2015.
    Published
  13. Conceição, J.; Fernandes, Sandra; Costa, Paulo; Sousa Lobo, J.M.. "Influence of controlling agent and fillers on acetylsalicylic acid release kinetics from matrix tablets". Paper presented in 1st European Conference on Pharmaceutics - Drug Delivery, Reims, 2015.
    Published
  14. Fernandes, Sandra; Conceição, J.; Costa, Paulo; Sousa Lobo, J. M.. "Sustained release matrix tablets: formulation and in vitro evaluation". Paper presented in IJUP’15 - 8.º Encontro de Jovens Investigadores da Universidade do Porto, Porto, 2015.
    Published
  15. Conceição, J.; Santos, A. ; Eiras, Filipa; Moreira, Gabriela; Correia, Inês; Gonçalves, Joana; Vaz, Joana; et al. "Topical bigels: Influence of the hydrogel on mechanical and sensory features". Paper presented in 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisboa, 2014.
    Published
  16. Conceição, J.; Estanqueiro, Marilene; Amaral, Maria Helena; Lobão, Paulo; Costa, Paulo; Sousa Lobo, J.M.. "Development and characterization of buccal bilayer tablets containing microparticles of ibuprofen". Paper presented in Xth Spanish-Portuguese Conference on Controlled Drug Delivery (SPLC-CRS 2013), Valência, 2013.
    Published
Conference paper
  1. Nascimento, Cecília; Sousa, Filipa; Reis, Salette; Costa, Paulo. "DESENVOLVIMENTO DE NANOPARTÍCULAS LIPÍDICAS COM NISTATINA PARA UMA AÇÃO ANTIFÚNGICA". 2023.
    10.29327/1192726.1-51
  2. Nascimento, Cecília; Sousa, Filipa; Reis, Salette; Costa, Paulo. "DESENVOLVIMENTO E CARACTERIZAÇÃO DE UM HIDROGEL COM NANOPARTÍCULAS LIPÍDICAS CONTENDO NISTATINA". 2023.
    10.29327/1192726.1-50
  3. Diana Pinto; María de la Luz Cádiz-Gurrea; Victor de Freitas; Paulo C. Costa; Bruno Sarmento; Cristina Delerue-Matos; Francisca Rodrigues. "Castanea sativa Shells: Is Cosmetic Industry a Prominent Opportunity to Valorize This Agro-Waste?". 2021.
    10.3390/Foods2021-11048
  4. Moreira, Joana; Durães, Fernando; Freitas-da-Silva, Joana; Szemerédi, Nikoletta; Pinto, Eugenia; Costa, Paulo; Pinto, Madalena; et al. "New chalcone analogues with potential bacterial efflux pump inhibitory effect". Paper presented in Proceedings of the 6th International Electronic Conference on Medicinal Chemistry, 2020.
    Published • 10.3390/ECMC2020-07489 (registering DOI)
  5. Sousa, Emília; Durães, Fernando; Barbosa, Filipa; Freitas-Silva, Joana; Costa, Paulo; Pinto, Madalena. "In silico studies of bacterial efflux pump inhibition by thioxanthones and their synergistic antibacterial activity". Paper presented in 5th International Electronic Conference on Medicinal Chemistry, 2019.
    10.3390/ecmc2019-06300
  6. Maria Freitas; Henri P. A. Nouws; Cristina Delerue-Matos. "Nano- and Micro Material-Based Electrochemical Bioassays for the Non-Invasive Detection of HER2-ECD, a Breast Cancer Biomarker". 2019.
    10.3390/proceedings2019015020
Conference poster
  1. Macedo, Catarina; Silva, Ana Margarida; Ferreira, Ana Sofia; Cádiz-Gurrea, María de la Luz; Fernández-Ochoa, Álvaro; Segura-Carretero, Antonio; delerue-matos, C; Costa, Paulo; Rodrigues, Francisca. "From discarded to desirable: Actinidia arguta (kiwiberry) as a source of health-promoting compounds". Paper presented in 6th ISEKI-Food E-conference, 2023.
  2. Inês Teixeira, Maria; Lopes, Carla M.; Gonçalves, Hugo; Catita, José; Silva, Ana Margarida; Rodrigues, Francisca; Amaral, Maria Helena; Costa, Paulo. "Potential neuroprotective effect of lactoferrin-functionalized lipid nanoparticles in Amyotrophic Lateral Sclerosis (ALS)". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  3. Silva, Ana Margarida; Almeida, Andreia; Dall'Acqua, Stefano; Loschi, Francesca; Sarmento, Bruno; Costa, Paulo; Delerue-Matos, Crstina; Rodrigues, Francisca. "In vitro and in vivo antioxidant properties of Actinidia arguta leaves obtained by Ultrasound assisted extraction". Paper presented in International Meeting Molecules 4 Life, 2023.
  4. Silva, Ana Margarida; Almeida, Andreia; Dall'Acqua, Stefano; Loschi, Francesca; Sarmento, Bruno; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Actinidia arguta leaves: An overview of antioxidant activity, intestinal permeation and health effects". Paper presented in XXXI International Conference on Polyphenols, 2023.
  5. Teixeira, Maria Inês; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. Corresponding author: Teixeira, Maria Inês. "Optimization of lipid nanoparticles to improve brain drug delivery in amyotrophic lateral sclerosis (ALS) (P-095)". Paper presented in 12th International Colloids Conference 2023, 2023.
  6. Teixeira, M.I.; Lopes, C.M.; Gonçalves, Hugo; José Catita; Silva, Ana Margarida; Francisca Rodrigues; Amaral, Maria Helena; Costa, Paulo. "Optimization of lipid nanoparticles to improve brain drug delivery in amyotrophic lateral sclerosis (ALS)". Paper presented in 12th International Colloids Conference, 11th-14th June, Palma, Mallorca, Spain, 2023.
  7. Ferreira, Ana Sofia; Silva, Ana Margarida; Pinto, Diana; Ferraz, Ricardo; Jaroslava Svarc-Gajic; Costa, Paulo; Cristina Delerue-Matos; Rodrigues, Francisca. Corresponding author: Rodrigues, Francisca. "Repurposing Chestnut Shells as Antioxidant Rich Ingredient". Paper presented in 1st International Conference on Antioxidants, 2023.
  8. Silva, Ana Margarida; Almeida, Andreia; Dall'Acqua, Stefano; Loschi, Francesca; Sarmento, Bruno; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Actinidia arguta leaves potential nutraceutical ingredient: an in vitro and in vivo screening". Paper presented in Dare2Change conference, 2023.
  9. Ferreira, Ana Sofia; Silva, Ana Margarida; Pinto, Diana; Ferraz, Ricardo; Manuela M. Moreira; Jaroslava Svarc-Gajic; Costa, Paulo; Cristina Delerue-Matos; Rodrigues, Francisca. Corresponding author: Rodrigues, Francisca. "Potential therapeutic application of chestnut shells in oral mucositis treatment: Green extraction of polyphenols". Paper presented in Dare 2 Change, 2023.
  10. Silva, Ana Margarida; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Valorization of Actinidia arguta leaves as cosmetic ingredient: In-vitro and in-vivo safety and efficacy evaluation". Paper presented in Dare2Change conference, 2023.
  11. Silva, Ana Margarida; Almeida, Andreia; Dall'Acqua, Stefano; Loschi, Francesca; Sarmento, Bruno; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Assessment of the 3D in-vitro permeability and in- vivo antioxidant effects of the Actinidia arguta leaves". Paper presented in 4th SPLC-CRS Young Scientists Meeting, 2023.
  12. Ferreira, Ana Sofia; Silva, Ana Margarida; Pinto, Diana; Ferraz, Ricardo; Jaroslava Svarc-Gajic; Costa, Paulo; Cristina Delerue-Matos; Francisca Rodrigues. Corresponding author: Francisca Rodrigues. "From agricultural waste to antioxidant-rich extracts: Green extraction of polyphenols from chestnut shells". Paper presented in 4 th SPLC-CRS: Young Scientists Meeting, 2023.
  13. Silva, Ana Margarida; Almeida, Andreia; Sarmento, Bruno; Costa, Paulo; Delerue-Matos, Crstina; Rodrigues, Francisca. "Insights into the development of Actinidia arguta leaves nutraceutical ingredient: Antioxidant activity and bioavailability study in rats". Paper presented in 5º Encontro em Biotecnologia Medicinal/ 2nd Iberian Congress on Medicinal Biotechnology, 2022.
  14. Ferreira, Ana Sofia; Silva, Ana Margarida; Pinto, Diana; Moreira, Manuela; Ferraz, Ricardo; Švarc-Gajic, Jaroslava; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Sustainable valorization of phenolic compounds from Castanea sativa shells for pharmaceutical application". Paper presented in 5º Encontro em Biotecnologia Medicinal/ 2nd Iberian Congress on Medicinal Biotechnology, 2022.
  15. Teixeira, M.I.; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. "Brain Drug Delivery of Riluzole by means of Lactoferrin Functionalized Nanostructured Lipid Carriers". Paper presented in The International Nanotech & Nanoscience Conference & Exhibition Nanotech France 2022, 15th-17th June, Paris, France, 2022.
  16. Macedo, Catarina; Silva, Ana Margarida; Costa, Paulo; C. Delerue-Matos; Rodrigues, Francisca. "Valorization of kiwiberry leaves by Subcritical Water Extraction: Screening of antioxidant/antiradical activity and intestinal effects". Paper presented in 4th International Symposium on Lipid Oxidation and Antioxidants, 2022.
  17. Silva, Ana Margarida; Garcia, Juliana; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Highlighting the bioactivity of kiwiberry leaves extracts as cosmetic ingredient: An exploratory "in vitro" study". Paper presented in 2º Encuentro Ibérico de Fluidos Supercríticos, 2022.
  18. Pinto, Diana; Cádiz-Gurrea, María de la Luz; Freitas, Vitor; Costa, Paulo; Sarmento, Bruno; delerue-matos, C; Rodrigues, Francisca. "Study of a possible cosmetic ingredient recovered from Castanea sativa shells using a green technology approach through in-vitro and ex-vivo assays". Paper presented in Controlled Release Society 2021 ¿ Virtual Annual Meeting, 2021.
  19. Silva, Ana Margarida; Pinto, Diana; Fernandes, Iva; Freitas, Vitor; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Microwave-assisted extraction of kiwiberry leaves for cosmetic purposes: Phenolic composition and bioactivity screening". Paper presented in XXX International Conference on Polyphenols, 2021.
  20. Teixeira, M.I.; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. "Lactoferrin functionalized NLC for Amyotrophic Lateral Sclerosis". Paper presented in EUFEPS Annual Meeting 2021 (Virtual Meeting), 2021.
  21. Silva, Ana Margarida; Pinto, Diana; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Microwave extraction of kiwiberry leaves: A promising source of bioactive compounds". Paper presented in International IBERPHENOL Conference, 2020.
  22. Freitas-Silva, Joana; Nakayama, Darlan G.; Durães, Fernando; Moreira, Joana; Neves, Ana R.; Barbosa, Filipa; Resende, Diana; et al. "Antimicrobials from the sea: inspiring models to revert multidrug resistance". Paper presented in Blue Think Conference: Share Science, Spread Knowledge, p.90-91, 2020.
  23. Durães, Fernando; Barbosa, Filipa; Freitas-Silva, Joana; Pinto, Madalena; Pinto, Eugénia; Costa, Paulo; Sousa, Emília. "Design, synthesis and antimicrobial activity of potential modulators of bacterial efflux pumps". Paper presented in 13º Encontro Nacional de Química Orgânica/6º Encontro Nacional de Química Terapêutica, 2020.
  24. Durães, Fernando; Moreira, Joana; Neves, Ana Rita; Barbosa, Filipa; Freitas-Silva, Joana; Cidade, Honorina; Correia-da-Silva, Marta; et al. "Antimicrobials from the Sea: Models for Innovative Agents to Revert Multidrug Resistance". Paper presented in Day of the Microbiology Laboratory, Faculty of Pharmacy, University of Porto, 2019.
  25. Durães, Fernando; Barbosa, Filipa; Freitas-Silva, Joana; Cravo, Sara; Costa, Paulo; Pinto, Madalena; Sousa, Emília. "From the computer to the the lab bench: design, synthesis and synergistic activity with antibacterial drugs of aminated thioxanthones". Paper presented in EUROPIN Summer School on Drug Design – Vienna, 2019.
  26. Teixeira, M.I.; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. "Riluzole-loaded lipid nanoparticles for brain targeted delivery". Paper presented in 9th International Colloids Conference, 16th - 19th June, Sitges, Barcelona, Spain, 2019.
  27. Pereira, Andreia T; Patrícia C. Henriques; Schneider, Karl; Costa, Paulo; Martins, M. Cristina L.; Magalhães, Fernão D.; Bergmeister, Helga; Gonçalves, Inês. "Biocompatible graphene oxide-containing hydrogels with extreme stiffness and high-strength.". Paper presented in Graphene Week, 2019.
  28. Teixeira, M.I.; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. "Development of an HPCL method for the quantification of riluzole". Paper presented in 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 19th - 22nd March, Granada, Spain, 2018.
  29. Teixeira, M.I.; Lopes, C.M.; Amaral, Maria Helena; Costa, Paulo. "Screening of lipids by differential scanning calorimetry (DSC) for production of lipid nanoparticles". Paper presented in 9th Meeting of the Analytical Chemistry Division, 26th-27th March, Complexo ICBAS/FFUP, Porto, Portugal, 2018.
  30. Conceição, J.; Amorim, Andreia; Vieira, Cátia; Simões, A. M.; Costa, Paulo; Sousa Lobo, J.M.. "Hydrophilic matrix tablets: Formulation and in vitro evaluation". Paper presented in 2nd European Conference on Pharmaceutics - Novel dosage forms and innovative technologies, 2017.
  31. Patrícia C. Henriques; Costa, Lia; Sampaio, Paula; Gomez-Lazaro, Maria; Maia, André; Martins, M. Cristina L.; Costa, Paulo; Gonçalves, Inês. "Exploring bioimaging strategies to study chitosan microspheres interaction with gastric mucosa.". Paper presented in BioImaging 2015 - 4th International Symposium in applied Bioimaging: The Pre-Clinical Challenge in 3D, 2015.
  32. Marques, Claudia; Bárbara B. Mendes; Azevedo, A. R.; Costa, Paulo; Martins, Susana; Sarmento, Bruno; Ferreira, Domingos. "Drug loaded-lipid nanoparticles as carriers for drug delivery to glioma using an in vitro blood brain barrier model.". Paper presented in 11th International Conference on Nanosciences & Nanotechnologies, 2014.
  33. Marques, Claudia; Mendes, Bárbara; Azevedo, Ana Rita; Costa, Paulo; Martins, Susana; Ferreira, Domingos; Sarmento, Bruno. "Drug loaded-lipid nanoparticles as carriers for drug delivery to gliomas using an in vitro blood brain barrier model". Paper presented in 11th International Conference on Nanosciences & Nanotechnologies (NN14), 2014.
  34. Mendes, Bárbara; Marques, Claudia; Martins, Susana; Costa, Paulo; Ferreira, Domingos; Sarmento, Bruno. "Development of an in vitro Blood-Brain Barrier model for drug-loaded solid lipid nanoparticles delivery". Paper presented in 5th International Conference on Advanced Nanomaterials (ANM2014), 2014.
  35. Mendes, Bárbara; Marques, Claudia; Costa, Paulo; Ferreira, Domingos; Sarmento, Bruno. "Development and characterization of a co-culture two-dimensional blood-brain barrier for the study and correlation of drug permeation". Paper presented in 7.º Encontro Investigação Jovem da Universidade do Porto, 2014.
  36. Henriques, Patrícia C.; Sampaio, Paula; Gomez-Lazaro, Maria; Maia, André; Gouveia, António; Lopes, José Manuel; Magalhães, Ana; et al. "Chitosan microparticles as a binding system against Helicobacter pylori.". Paper presented in 6th Symposium on Bioengineering, 2014.
  37. Almeida, Isabel; Costa, Paulo; Barbosa, Carlos Maurício; Bahia, M.F.. "Comparação da Capacidade Hidratante de Três Formulações". Paper presented in Congresso Nacional dos Farmacêuticos 2003, Lisboa, Portugal, 2003.
Journal article
  1. Anna Elisabetta Maccarronello; Nunzio Cardullo; Ana Margarida Silva; Antonella Di Francesco; Paulo C. Costa; Francisca Rodrigues; Vera Muccilli. "From waste to bioactive compounds: A response surface methodology approach to extract antioxidants from Pistacia vera shells for postprandial hyperglycaemia management". Food Chemistry (2024): https://doi.org/10.1016/j.foodchem.2024.138504.
    10.1016/j.foodchem.2024.138504
  2. Ana Alves; Ana Margarida Silva; Claúdia Nunes; Sara Cravo; Salette Reis; Madalena Pinto; Emília Sousa; et al. "The Synthesis and Characterization of a Delivery System Based on Polymersomes and a Xanthone with Inhibitory Activity in Glioblastoma". Life (2024): https://doi.org/10.3390/life14010132.
    10.3390/life14010132
  3. Ana Alves; Ana M. Silva; Joana Moreira; Claúdia Nunes; Salette Reis; Madalena Pinto; Honorina Cidade; et al. "Polymersomes for Sustained Delivery of a Chalcone Derivative Targeting Glioblastoma Cells". Brain Sciences (2024): https://doi.org/10.3390/brainsci14010082.
    10.3390/brainsci14010082
  4. Salústio, P.J.; Amaral, M.H.; Costa, P.C.. "Different Carriers for Use in Dry Powder Inhalers: Characteristics of Their Particles". Journal of Aerosol Medicine and Pulmonary Drug Delivery (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85201050168&partnerID=MN8TOARS.
    10.1089/jamp.2023.0029
  5. Marques, A.C.; Costa, P.C.; Velho, S.; Amaral, M.H.. "Analytical Techniques for Characterizing Tumor-Targeted Antibody-Functionalized Nanoparticles". Life 14 4 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85193252398&partnerID=MN8TOARS.
    10.3390/life14040489
  6. Maccarronello, A.E.; Cardullo, N.; Silva, A.M.; Di Francesco, A.; Costa, P.C.; Rodrigues, F.; Muccilli, V.. "Unlocking the nutraceutical potential of Corylus avellana L. shells: microwave-assisted extraction of phytochemicals with antiradical and anti-diabetic properties". Journal of the Science of Food and Agriculture (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85200004068&partnerID=MN8TOARS.
    10.1002/jsfa.13770
  7. Marques, A.C.; Costa, P.C.; Velho, S.; Amaral, M.H.. "Rheological and Injectability Evaluation of Sterilized Poloxamer-407-Based Hydrogels Containing Docetaxel-Loaded Lipid Nanoparticles". Gels 10 5 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85194428460&partnerID=MN8TOARS.
    10.3390/gels10050307
  8. Teixeira, F.; Silva, A.M.; Macedo, C.; Estevinho, B.; Sut, S.; Dall'Acqua, S.; Delerue-Matos, C.; Costa, P.C.; Rodrigues, F.. "Design of advanced buccal films with kiwiberry extract to prevent oral mucositis: From in vitro buccal models to ex vivo studies". Journal of Drug Delivery Science and Technology 96 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85192103475&partnerID=MN8TOARS.
    10.1016/j.jddst.2024.105725
  9. Macedo, C.; Costa, P.C.; Rodrigues, F.. "Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma". Food Research International 175 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85178632514&partnerID=MN8TOARS.
    10.1016/j.foodres.2023.113770
  10. Saraiva, N.M.; Alves, A.; Costa, P.C.; Correia-da-Silva, M.. "Click Chemistry in Polymersome Technology". Pharmaceuticals 17 6 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85197338001&partnerID=MN8TOARS.
    10.3390/ph17060747
  11. Ferreira, A.S.; Silva, A.M.; Laveriano-Santos, E.P.; Lozano-Castellón, J.; Lamuela-Raventós, R.M.; Švarc-Gajíc, J.; Delerue-Matos, C.; et al. "Development and characterization of spray-drying microparticles loaded with chestnut shells extract: New insights for oral mucositis therapy". Powder Technology 446 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85201324016&partnerID=MN8TOARS.
    10.1016/j.powtec.2024.120182
  12. Jéssica Adriana Jesus; Thays Nicolli Fragoso da Silva; Ilza Maria Oliveira Sousa; Aurea Favero Ferreira; Márcia Dalastra Laurenti; Paulo Cardoso da Costa; Domingos de Carvalho Ferreira; Luiz Felipe Domingues Passero. "Nanostructured Lipid Carriers as Robust Systems for Lupeol Delivery in the Treatment of Experimental Visceral Leishmaniasis". Pharmaceuticals (2023): https://doi.org/10.3390/ph16121646.
    10.3390/ph16121646
  13. Rafaela Malta; Ana Camila Marques; Paulo Cardoso da Costa; Maria Helena Amaral. "Stimuli-Responsive Hydrogels for Protein Delivery". Gels (2023): https://doi.org/10.3390/gels9100802.
    10.3390/gels9100802
  14. Inês Teixeira, Maria; Lopes, Carla M.; Gonçalves, Hugo; Catita, José; Silva, Ana Margarida; Rodrigues, Francisca; Helena Amaral, Maria; Costa, Paulo. "Riluzole-loaded lipid nanoparticles for brain delivery: Preparation, optimization and characterization". Journal of Molecular Liquids 388 (2023): 122749. http://dx.doi.org/10.1016/j.molliq.2023.122749.
    10.1016/j.molliq.2023.122749
  15. Sousa, Filipa; Nascimento, Cecília; Ferreira, Domingos; Reis, Salette; Costa, Paulo. "Reviving the interest in the versatile drug nystatin: A multitude of strategies to increase its potential as an effective and safe antifungal agent". Advanced Drug Delivery Reviews 199 (2023): 114969. http://dx.doi.org/10.1016/j.addr.2023.114969.
    10.1016/j.addr.2023.114969
  16. Filipa Teixeira; Ana Margarida Silva; Stefania Sut; Stefano Dall’Acqua; Cristina Delerue-Matos; Berta Estevinho; Paulo C. Costa; Francisca Rodrigues. "Development and Characterization of Microparticles with Actinidia arguta Leaves Extract by Spray-Drying: A New Mind-Set Regarding Healthy Compounds for Oral Mucositis". Antioxidants (2023): https://doi.org/10.3390/antiox12081496.
    10.3390/antiox12081496
  17. Ana Camila Marques; Paulo Cardoso Costa; Sérgia Velho; Maria Helena Amaral. "Injectable Poloxamer Hydrogels for Local Cancer Therapy". Gels (2023): https://doi.org/10.3390/gels9070593.
    10.3390/gels9070593
  18. Ana Margarida Silva; Paulo C. Costa; Cristina Delerue-Matos; Francisca Rodrigues. "Mathematical development and in vivo safety and efficacy studies of a topical formulation containing Actinidia arguta leaves extract". Journal of Drug Delivery Science and Technology (2023): https://doi.org/10.1016/j.jddst.2023.104547.
    10.1016/j.jddst.2023.104547
  19. Inês Ferreira; Ana Camila Marques; Paulo Cardoso Costa; Maria Helena Amaral. "Effects of Steam Sterilization on the Properties of Stimuli-Responsive Polymer-Based Hydrogels". Gels (2023): https://doi.org/10.3390/gels9050385.
    10.3390/gels9050385
  20. Macedo, Catarina; Silva, Ana Margarida; Ferreira, Ana Sofia; Cádiz-Gurrea, María de la Luz; Fernández-Ochoa, Álvaro; Segura-Carretero, Antonio; Delerue-Matos, Cristina; Costa, Paulo; Rodrigues, Francisca. "Insights into the polyphenols extraction from Actinidia arguta fruit (kiwiberry): A source of pro-healthy compounds". Scientia Horticulturae 313 (2023): 111910. http://dx.doi.org/10.1016/j.scienta.2023.111910.
    Published
  21. Ana Camila Marques; Paulo C. Costa; Sérgia Velho; Maria Helena Amaral. "Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15010216.
    10.3390/pharmaceutics15010216
  22. Teixeira, M.I.; Lopes, C.M.; Amaral, M.H.; Costa, P.C.. "Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases". Colloids and Surfaces B: Biointerfaces 221 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85141487824&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2022.112999
  23. Nascimento, Cecilia; Sousa, Filipa; Reis, Salette; Costa, Paulo. "Development of lipid nanoparticles with nystatin for an antifungal action". (2023): https://doi.org/10.21814/jus.4677.
    https://doi.org/10.21814/jus.4677
  24. Macedo, C.; Silva, A.M.; Ferreira, A.S.; Cádiz-Gurrea, M.D.L.L.; Fernández-Ochoa, Á.; Segura-Carretero, A.; Delerue-Matos, C.; Costa, P.; Rodrigues, F.. "Insights into the polyphenols extraction from Actinidia arguta fruit (kiwiberry): A source of pro-healthy compounds". Scientia Horticulturae 313 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85147666482&partnerID=MN8TOARS.
    10.1016/j.scienta.2023.111910
  25. Salústio, P.J.; Pais, B.V.; Malta, T.; Nunes, T.; Sousa e Silva, J.P.; Costa, P.J.. "Flow behavior under shear cell analysis of two HMPC grades". Powder Technology 430 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85173252807&partnerID=MN8TOARS.
    10.1016/j.powtec.2023.119025
  26. Ana Sofia Ferreira; Ana Margarida Silva; Diana Pinto; Manuela M. Moreira; Ricardo Ferraz; Jaroslava Švarc-Gajic; Paulo C. Costa; Cristina Delerue-Matos; Francisca Rodrigues. "New Perspectives on the Sustainable Employment of Chestnut Shells as Active Ingredient against Oral Mucositis: A First Screening". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232314956.
    10.3390/ijms232314956
  27. Ana Margarida Silva; Andreia Almeida; Stefano Dall’Acqua; Francesca Loschi; Bruno Sarmento; Paulo C. Costa; Cristina Delerue-Matos; Francisca Rodrigues. "Insights into the 3D In Vitro Permeability and In Vivo Antioxidant Protective Effects of Kiwiberry Leaf Extract: A Step Forward to Human Nutraceutical Use". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms232214130.
    10.3390/ijms232214130
  28. Ana Margarida Silva; Paulo C. Costa; Cristina Delerue-Matos; Francisca Rodrigues. "Assessment of a Formulation Containing a Castanea sativa Shells Extract on Skin Face Parameters: In Vivo Evaluation". Processes (2022): https://doi.org/10.3390/pr10112230.
    10.3390/pr10112230
  29. Sónia N. Pedro; Maria S. M. Mendes; Bruno M. Neves; Isabel Filipa Almeida; Paulo Costa; Inês Correia-Sá; Carla Vilela; et al. "Deep Eutectic Solvent Formulations and Alginate-Based Hydrogels as a New Partnership for the Transdermal Administration of Anti-Inflammatory Drugs". Pharmaceutics 14 4 (2022): 827-827. https://doi.org/10.3390/pharmaceutics14040827.
    10.3390/pharmaceutics14040827
  30. Ana Margarida Silva; Ana Sofia Luís; Manuela M. Moreira; Ricardo Ferraz; Tanja Brezo-Borjan; Jaroslava Švarc-Gajic; Paulo C. Costa; Cristina Delerue-Matos; Francisca Rodrigues. "Influence of temperature on the subcritical water extraction of Actinidia arguta leaves: A screening of pro-healthy compounds". Sustainable Chemistry and Pharmacy 25 (2022): 100593-100593. https://doi.org/10.1016/j.scp.2021.100593.
    10.1016/j.scp.2021.100593
  31. Ana Margarida Silva; Diana Pinto; Manuela M. Moreira; Costa, P; Cristina Delerue-Matos; Francisca Rodrigues. "Valorization of Kiwiberry Leaves Recovered by Ultrasound-Assisted Extraction for Skin Application: A Response Surface Methodology Approach". Antioxidants (2022): https://www.mdpi.com/2076-3921/11/4/763.
    10.3390/antiox11040763
  32. Maria Inês Teixeira; Carla Martins Lopes; Hugo Gonçalves; José Catita; Ana Margarida Silva; Francisca Rodrigues; Maria Helena Amaral; Paulo C. Costa. "Formulation, Characterization, and Cytotoxicity Evaluation of Lactoferrin Functionalized Lipid Nanoparticles for Riluzole Delivery to the Brain". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14010185.
    10.3390/pharmaceutics14010185
  33. David Daniel; João C. Campos; Paulo C. Costa; Bruno Nunes. "Toxicity of two drugs towards the marine filter feeder Mytilus spp, using biochemical and shell integrity parameters". Environmental Pollution 293 (2022): 118562-118562. https://doi.org/10.1016/j.envpol.2021.118562.
    10.1016/j.envpol.2021.118562
  34. Silva, A.M.; Garcia, J.; Dall'Acqua, S.; Costa, P.; Delerue-Matos, C.; Rodrigues, F.. "Eco-friendly insights on kiwiberry leaves valorization through in-vitro and in-vivo studies". Industrial Crops and Products 184 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85133954878&partnerID=MN8TOARS.
    10.1016/j.indcrop.2022.115090
  35. Amaral, L.; Rodrigues, F.; Silva, A.; Costa, P.; Delerue-Matos, C.; Vieira, E.F.. "Reinforcement of starch film with Castanea sativa shells polysaccharides: Optimized formulation and characterization". Food Chemistry 396 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85134341554&partnerID=MN8TOARS.
    10.1016/j.foodchem.2022.133609
  36. Silva, A.C.Q.; Pereira, B.; Lameirinhas, N.S.; Costa, P.C.; Almeida, I.F.; Dias-Pereira, P.; Correia-Sá, I.; et al. "Dissolvable Carboxymethylcellulose Microneedles for Noninvasive and Rapid Administration of Diclofenac Sodium". Macromolecular Bioscience (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85140264088&partnerID=MN8TOARS.
    10.1002/mabi.202200323
  37. Ferreira, A.S.; Macedo, C.; Silva, A.M.; Delerue-Matos, C.; Costa, P.; Rodrigues, F.. "Natural Products for the Prevention and Treatment of Oral Mucositis—A Review". International Journal of Molecular Sciences 23 8 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85128241179&partnerID=MN8TOARS.
    10.3390/ijms23084385
  38. Nágilla Oliveira; Maria de la Luz Cádiz-Gurrea; Ana Margarida Silva; Catarina Macedo; Francisca Rodrigues; Paulo Costa. "Development and Optimization of a Topical Formulation with Castanea sativa Shells Extract Based on the Concept “Quality by Design”". Sustainability (2021): https://doi.org/10.3390/su14010129.
    10.3390/su14010129
  39. Costa, Paulo. "Starch flow behavior alone and under different glidants action using the shear cell method". Drug Development and Industrial Pharmacy (2021): 1-10. http://dx.doi.org/10.1080/03639045.2021.2004158.
    10.1080/03639045.2021.2004158
  40. Ana Margarida Silva; Paulo C. Costa; Cristina Delerue-Matos; Piotr Latocha; Francisca Rodrigues. "Extraordinary composition of Actinidia arguta by-products as skin ingredients: A new challenge for cosmetic and medical skincare industries". Trends in Food Science & Technology (2021): https://doi.org/10.1016/j.tifs.2021.08.031.
    10.1016/j.tifs.2021.08.031
  41. Jéssica Adriana Jesus; Ilza Maria Oliveira Sousa; Thays Nicolli Fragoso da Silva; Aurea Favero Ferreira; Márcia Dalastra Laurenti; Leila Antonangelo; Caroline Silvério Faria; et al. "Preclinical Assessment of Ursolic Acid Loaded into Nanostructured Lipid Carriers in Experimental Visceral Leishmaniasis". Pharmaceutics 13 6 (2021): 908-908. https://doi.org/10.3390/pharmaceutics13060908.
    10.3390/pharmaceutics13060908
  42. Diana Pinto; Fátima Lameirão; Cristina Delerue-Matos; Francisca Rodrigues; Paulo Costa. "Characterization and Stability of a Formulation Containing Antioxidants-Enriched Castanea sativa Shells Extract". Cosmetics 8 2 (2021): 49-49. https://doi.org/10.3390/cosmetics8020049.
    10.3390/cosmetics8020049
  43. Ana Alves; Paulo Costa; Madalena Pinto; Domingos Ferreira; Marta Correia-da-Silva. "Small Molecules of Marine Origin as Potential Anti-Glioma Agents". Molecules (2021): https://doi.org/10.3390/molecules26092707.
    10.3390/molecules26092707
  44. Ana Margarida Silva; Diana Pinto; Iva Fernandes; Victor de Freitas; María de la Luz Cádiz-Gurrea; Paulo Costa; Cristina Delerue-Matos; Francisca Rodrigues. "An Insight into Kiwiberry Leaf Valorization: Phenolic Composition, Bioactivity and Health Benefits". Molecules (2021): https://doi.org/10.3390/molecules26082314.
    10.3390/molecules26082314
  45. Costa, Paulo. "Combining local antibiotic delivery with heparinized nanohydroxyapatite/collagen bone substitute: A novel strategy for osteomyelitis treatment". Materials Science and Engineering: C (2021): http://dx.doi.org/10.1016/j.msec.2020.111329.
    10.1016/j.msec.2020.111329
  46. Rafaela Malta; Joana B. Loureiro; Paulo Costa; Emília Sousa; Madalena Pinto; Lucília Saraiva; M. Helena Amaral. "Development of lipid nanoparticles containing the xanthone LEM2 for topical treatment of melanoma". Journal of Drug Delivery Science and Technology (2021): 102226-102226. https://doi.org/10.1016/j.jddst.2020.102226.
    10.1016/j.jddst.2020.102226
  47. Costa, Paulo. "Optimizing the extraction of phenolic antioxidants from chestnut shells by subcritical water extraction using response surface methodology". Food Chemistry (2021): http://dx.doi.org/10.1016/j.foodchem.2020.127521.
    10.1016/j.foodchem.2020.127521
  48. Costa, Paulo. "Oromucosal precursors of in loco hydrogels for wound-dressing and drug delivery in oral mucositis: Retain, resist, and release". Materials Science and Engineering: C (2021): http://dx.doi.org/10.1016/j.msec.2020.111413.
    10.1016/j.msec.2020.111413
  49. Pinto, D.; Cádiz-Gurrea, M.D.L.L.; Garcia, J.; Saavedra, M.J.; Freitas, V.; Costa, P.; Sarmento, B.; Delerue-Matos, C.; Rodrigues, F.. "From soil to cosmetic industry: Validation of a new cosmetic ingredient extracted from chestnut shells". Sustainable Materials and Technologies 29 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85108501727&partnerID=MN8TOARS.
    10.1016/j.susmat.2021.e00309
  50. Marques, A.C.; Costa, P.J.; Velho, S.; Amaral, M.H.. "Stimuli-responsive hydrogels for intratumoral drug delivery". Drug Discovery Today 26 10 (2021): 2397-2405. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105106991&partnerID=MN8TOARS.
    10.1016/j.drudis.2021.04.012
  51. Ludovico Esposito; Ana Isabel Barbosa; Tânia Moniz; Sofia Costa Lima; Paulo Costa; Christian Celia; Salette Reis. "Design and Characterization of Sodium Alginate and Poly(vinyl) Alcohol Hydrogels for Enhanced Skin Delivery of Quercetin". Pharmaceutics (2020): https://doi.org/10.3390/pharmaceutics12121149.
    10.3390/pharmaceutics12121149
  52. Costa, Paulo. "Influence of the Glidant on Diluent Flow Characterization Using Shear Cell Method". Journal of Pharmaceutical Innovation (2020): http://dx.doi.org/10.1007/s12247-020-09478-6.
    10.1007/s12247-020-09478-6
  53. Filipa Sousa; Domingos Ferreira; Salette Reis; Paulo Costa. "Current Insights on Antifungal Therapy: Novel Nanotechnology Approaches for Drug Delivery Systems and New Drugs from Natural Sources". Pharmaceuticals 13 9 (2020): 248-248. https://doi.org/10.3390/ph13090248.
    10.3390/ph13090248
  54. Costa, Paulo. "Orally administrated chitosan microspheres bind Helicobacter pylori and decrease gastric infection in mice". Acta Biomaterialia (2020): http://dx.doi.org/10.1016/j.actbio.2020.06.035.
    10.1016/j.actbio.2020.06.035
  55. Costa, Paulo. "Swellable Gelatin Methacryloyl Microneedles for Extraction of Interstitial Skin Fluid toward Minimally Invasive Monitoring of Urea". Macromolecular Bioscience (2020): http://dx.doi.org/10.1002/mabi.202000195.
    10.1002/mabi.202000195
  56. Daniela F.S. Fonseca; Paulo C. Costa; Isabel F. Almeida; Patrícia Dias-Pereira; Inês Correia-Sá; Verónica Bastos; Helena Oliveira; et al. "Pullulan microneedle patches for the efficient transdermal administration of insulin envisioning diabetes treatment". Carbohydrate Polymers 241 (2020): 116314-116314. https://doi.org/10.1016/j.carbpol.2020.116314.
    10.1016/j.carbpol.2020.116314
  57. Olena Dorosh; Manuela M. Moreira; Diana Pinto; Andreia F. Peixoto; Cristina Freire; Paulo Costa; Francisca Rodrigues; Cristina Delerue-Matos. "Evaluation of the Extraction Temperature Influence on Polyphenolic Profiles of Vine-Canes (Vitis vinifera) Subcritical Water Extracts". Foods (2020): https://doi.org/10.3390/foods9070872.
    10.3390/foods9070872
  58. Manuela M. Moreira; Francisca Rodrigues; Olena Dorosh; Diana Pinto; Paulo C. Costa; Jaroslava Švarc-Gajic; Cristina Delerue-Matos. "Vine-Canes as a Source of Value-Added Compounds for Cosmetic Formulations". Molecules 25 13 (2020): 2969-2969. https://doi.org/10.3390/molecules25132969.
    10.3390/molecules25132969
  59. Maria Inês Teixeira; Maria Helena Amaral; Costa, P; Lopes, C.M.; Dimitrios A. Lamprou. "Recent Developments in Microfluidic Technologies for Central Nervous System Targeted Studies". Pharmaceutics (2020): https://www.mdpi.com/1999-4923/12/6/542.
    10.3390/pharmaceutics12060542
  60. Costa, Paulo. "Freeze-Dried Softisan® 649-Based Lipid Nanoparticles for Enhanced Skin Delivery of Cyclosporine A". Nanomaterials (2020): http://dx.doi.org/10.3390/nano10050986.
    10.3390/nano10050986
  61. Costa, Paulo. "Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies". Journal of Controlled Release (2020): http://dx.doi.org/10.1016/j.jconrel.2020.01.035.
    10.1016/j.jconrel.2020.01.035
  62. Dionísio, Ricardo; Daniel, David; Arenas, Francisco; Campos, João C.; Costa, Paulo C.; Nunes, Bruno; Correia, Alberto Teodorico. "Effects of pH on salicylic acid toxicity in terms of biomarkers determined in the marine gastropod Gibbula umbilicalis". Marine Environmental Research (2020): 104995. http://dx.doi.org/10.1016/j.marenvres.2020.104995.
    10.1016/j.marenvres.2020.104995
  63. Fátima Lameirão; Diana Pinto; Elsa F. Vieira; Andreia F. Peixoto; Cristina Freire; Stefania Sut; Stefano Dall’Acqua; et al. "Green-Sustainable Recovery of Phenolic and Antioxidant Compounds from Industrial Chestnut Shells Using Ultrasound-Assisted Extraction: Optimization and Evaluation of Biological Activities In Vitro". Antioxidants 9 3 (2020): 267-267. https://doi.org/10.3390/antiox9030267.
    10.3390/antiox9030267
  64. Costa, Paulo. "Current insights on lipid nanocarrier-assisted drug delivery in the treatment of neurodegenerative diseases". European Journal of Pharmaceutics and Biopharmaceutics (2020): http://dx.doi.org/10.1016/j.ejpb.2020.01.005.
    10.1016/j.ejpb.2020.01.005
  65. Salústio, P.J.; Machado, M.; Nunes, T.; Sousa e Silva, J.P.; Costa, P.C.. "Lactose monohydrate flow characterization using shear cell method". Pharmaceutical Development and Technology (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85080141559&partnerID=MN8TOARS.
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  66. de Francisco, L.M.B.; Pinto, D.; Rosseto, H.C.; de Toledo, L.D.A.S.; dos Santos, R.S.; Costa, P.J.C.D.; Oliveira, M.B.P.P.; et al. "Design and characterization of an organogel system containing ascorbic acid microparticles produced with propolis by-product". Pharmaceutical Development and Technology 25 1 (2020): 54-67. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074047488&partnerID=MN8TOARS.
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  67. Salústio, P.J.; Inácio, C.; Nunes, T.; Sousa e Silva, J.P.; Costa, P.C.. "Flow characterization of a pharmaceutical excipient using the shear cell method". Pharmaceutical Development and Technology 25 2 (2020): 237-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075482302&partnerID=MN8TOARS.
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  68. Coelho, C.C.; Padrão, T.; Costa, L.; Pinto, M.T.; Costa, P.C.; Domingues, V.F.; Quadros, P.A.; Monteiro, F.J.; Sousa, S.R.. "The antibacterial and angiogenic effect of magnesium oxide in a hydroxyapatite bone substitute". Scientific Reports 10 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85095423920&partnerID=MN8TOARS.
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  69. J. Duarte; I.F. Almeida; M. Costa; E.S. Da Silva; J.L. Faria; J.M. Sousa Lobo; P.C. Costa; S. Scalia. "Alginate microparticles as carriers for the UV filter 2-ethylhexyl 4-methoxycinnamate: Influence on photostability". International Journal of Cosmetic Science (2019): https://doi.org/10.1111/ics.12578.
    10.1111/ics.12578
  70. Eduarda S. Morais; Nuno H.C.S. Silva; Tânia E. Sintra; Sónia A.O. Santos; Bruno Miguel Neves; Isabel F. Almeida; Paulo C. Costa; et al. "Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded with phenolic-based ionic liquids for cutaneous application". Carbohydrate Polymers 206 (2019): 187-197. https://doi.org/10.1016/j.carbpol.2018.10.051.
    10.1016/j.carbpol.2018.10.051
  71. Ana Alves; Marta Correia-da-Silva; Claúdia Nunes; E Sousa; Patrícia M. A. Silva; Hassan Bousbaa; Francisca Rodrigues; et al. "Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations". Molecules (2019): http://www.mdpi.com/1420-3049/24/3/409.
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  72. Costa, Paulo. "Mechanical Properties of Topical Anti-Psoriatic Medicines: Implications for Patient Satisfaction with Treatment". (2019): http://dx.doi.org/10.1208/s12249-018-1246-2.
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  73. Campos, J.C.; Ferreira, D.C.; Lima, S.; Reis, S.; Costa, P.J.. "Swellable polymeric particles for the local delivery of budesonide in oral mucositis". International Journal of Pharmaceutics 566 (2019): 126-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066149158&partnerID=MN8TOARS.
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  74. Pereira, A.T.; Henriques, P.C.; Costa, P.C.; Martins, M.C.L.; Magalhães, F.D.; Gonçalves, I.C.. "Graphene oxide-reinforced poly(2-hydroxyethyl methacrylate) hydrogels with extreme stiffness and high-strength". Composites Science and Technology 184 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072771699&partnerID=MN8TOARS.
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  75. Campos, Joao C; Cunha, Joao D; Ferreira, Domingos C; Reis, Salette; Costa, Paulo J. "Challenges in the local delivery of peptides and proteins for oral mucositis management.". European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 128 (2018): 131-146. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29702221&KeyUID=MEDLINE:29702221.
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  76. De Francisco, L.M.B.; Pinto, D.; Rosseto, H.C.; De Toledo, L.D.A.S.; Dos Santos, R.S.; Costa, P.; Rodrigues, F.; et al. "Correction: Development of a microparticulate system containing Brazilian propolis by-product and gelatine for ascorbic acid delivery: evaluation of intestinal cell viability and radical scavenging activity(Food and Function (2018) DOI: 10.1039/c8fo00863a)". Food and Function 9 8 (2018): 4518-4518. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051997308&partnerID=MN8TOARS.
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  77. Filipa Teixeira, A.; Luisa Matos, M.; Pedrosa, Luciana; Costa, Paulo. "Analyse of occupational noise and whole-body vibration exposure at bus drivers-case study". Occupational Safety and Hygiene Vi (2018): https://publons.com/wos-op/publon/19296286/.
  78. Rocha, V.; Marques, C.; Figueiredo, J.L.; Gaio, A.R.; Costa, P.C.; Sousa Lobo, J.M.; Almeida, I.F.. "In vitro cytotoxicity evaluation of resveratrol-loaded nanoparticles: Focus on the challenges of in vitro methodologies". Food and Chemical Toxicology 103 (2017): 214-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015416193&partnerID=MN8TOARS.
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  79. Neves, N.; Campos, B.B.; Almeida, I.F.; Costa, P.C.; Cabral, A.T.; Barbosa, M.A.; Ribeiro, C.C.. "Strontium-rich injectable hybrid system for bone regeneration". Materials Science and Engineering C 59 (2016): 818-827. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946573448&partnerID=MN8TOARS.
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  80. Carvalho, I.M.; Coelho, P.B.; Costa, P.C.; Marques, C.S.; Oliveira, R.S.; Ferreira, D.C.. "Current Neurogenic and Neuroprotective Strategies to Prevent and Treat Neurodegenerative and Neuropsychiatric Disorders". NeuroMolecular Medicine 17 4 (2015): 404-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947127602&partnerID=MN8TOARS.
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  81. Mendes, B.; Marques, C.; Carvalho, I.; Costa, P.; Martins, S.; Ferreira, D.; Sarmento, B.. "Influence of glioma cells on a new co-culture in vitro blood-brain barrier model for characterization and validation of permeability". International Journal of Pharmaceutics 490 1-2 (2015): 94-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929990184&partnerID=MN8TOARS.
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  82. Almeida, I.F.; Maleckova, J.; Saffi, R.; Monteiro, H.; Góios, F.; Amaral, M.H.; Costa, P.C.; et al. "Characterization of an antioxidant surfactant-free topical formulation containing Castanea sativa leaf extract". Drug Development and Industrial Pharmacy 41 1 (2015): 148-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918841093&partnerID=MN8TOARS.
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  83. Almeida, I.F.; Pinto, A.S.; Monteiro, C.; Monteiro, H.; Belo, L.; Fernandes, J.; Bento, A.R.; et al. "Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocyte cell line". Journal of Photochemistry and Photobiology B: Biology 144 (2015): 28-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922791203&partnerID=MN8TOARS.
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  84. Sousa, S.; Gomes, A.M.; Pintado, M.M.; Silva, J.P.; Costa, P.; Amaral, M.H.; Duarte, A.C.; et al. "Characterization of freezing effect upon stability of, probiotic loaded, calcium-alginate microparticles". Food and Bioproducts Processing 93 (2015): 90-97. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922256813&partnerID=MN8TOARS.
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  85. Carvalho, I.M.; Marques, C.S.; Oliveira, R.S.; Coelho, P.B.; Costa, P.C.; Ferreira, D.C.. "Sustained drug release by contact lenses for glaucoma treatment - A review". Journal of Controlled Release 202 (2015): 76-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922575853&partnerID=MN8TOARS.
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  86. Matias, A.R.; Ferreira, M.; Costa, P.; Neto, P.. "Skin colour, skin redness and melanin biometric measurements: Comparison study between Antera 3D, Mexameter and Colorimeter". Skin Research and Technology 21 3 (2015): 346-362. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937023284&partnerID=MN8TOARS.
    10.1111/srt.12199
  87. Afonso, S.; Horita, K.; Sousa E Silva, J.P.; Almeida, I.F.; Amaral, M.H.; Lobão, P.A.; Costa, P.C.; et al. "Photodegradation of avobenzone: Stabilization effect of antioxidants". Journal of Photochemistry and Photobiology B: Biology 140 (2014): 36-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905247944&partnerID=MN8TOARS.
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  88. Almeida, I.F.; Costa, P.C.; Fernanda Bahia, M.. "Optimization of a surfactant-free antioxidant formulation using response surface methodology". Drug Development and Industrial Pharmacy 40 1 (2014): 120-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890450642&partnerID=MN8TOARS.
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  89. Silva, N.H.C.S.; Drumond, I.; Almeida, I.F.; Costa, P.; Rosado, C.F.; Neto, C.P.; Freire, C.S.R.; Silvestre, A.J.D.. "Topical caffeine delivery using biocellulose membranes: A potential innovative system for cellulite treatment". Cellulose 21 1 (2014): 665-674. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893668001&partnerID=MN8TOARS.
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  92. Conceição, Jaime; Estanqueiro, Marilene; Amaral, Maria Helena; Lobão, Paulo; Costa, Paulo. "Development and characterization of buccal bilayer tablets containing microparticles with ibuprofen". American Journal of Medical Sciences and Medicine 2 5 (2014): 109-114. http://www.sciepub.com/AJMSM/abstract/3062.
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  95. Neto, P.; Ferreira, M.; Bahia, F.; Costa, P.. "Improvement of the methods for skin mechanical properties evaluation through correlation between different techniques and factor analysis". Skin Research and Technology 19 4 (2013): 405-416. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885476402&partnerID=MN8TOARS.
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  96. Borges, S.; Costa, P.; Silva, J.; Teixeira, P.. "Effects of processing and storage on pediococcus pentosaceus SB83 in vaginal formulations: Lyophilized powder and tablets". BioMed Research International 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880152098&partnerID=MN8TOARS.
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  97. Salústio, P.J.; Pinto, J.F.; Costa, P.C.; Cabral-Marques, H.M.. "Release profiles of indometacin in ß-cyclodextrin complexes from HPMC capsules". Journal of Inclusion Phenomena and Macrocyclic Chemistry 75 1-2 (2013): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873919480&partnerID=MN8TOARS.
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  98. E Silva, J.P.S.; Splendor, D.; Gonçalves, I.M.B.; Costa, P.; Sousa Lobo, J.M.. "Note on the measurement of bulk density and tapped density of powders according to the European pharmacopeia". AAPS PharmSciTech 14 3 (2013): 1098-1100. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890152920&partnerID=MN8TOARS.
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  100. Sousa, S.; Gomes, A.M.; Pintado, M.M.; Malcata, F.X.; Silva, J.P.; Sousa, J.M.; Costa, P.; et al. "Encapsulation of probiotic strains in plain or cysteine-supplemented alginate improves viability at storage below freezing temperatures". Engineering in Life Sciences 12 4 (2012): 457-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865537711&partnerID=MN8TOARS.
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    10.1111/j.1365-2621.2011.02855.x
  102. Rodrigues, D.; Sousa, S.; Gomes, A.M.; Pintado, M.M.; Silva, J.P.; Costa, P.; Amaral, M.H.; Rocha-Santos, T.; Freitas, A.C.. "Storage Stability of Lactobacillus paracasei as Free Cells or Encapsulated in Alginate-Based Microcapsules in Low pH Fruit Juices". Food and Bioprocess Technology 5 7 (2012): 2748-2757. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867555881&partnerID=MN8TOARS.
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  103. Salústio, P.J.; Feio, G.; Figueirinhas, J.L.; Cabral-Marques, H.M.; Costa, P.C.; Pinto, J.F.. "Release profile of ibuprofen in ß-cyclodextrin complexes from two different solid dosage forms". Powder Technology 221 (2012): 245-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858620569&partnerID=MN8TOARS.
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  104. Rodrigues, D.; Sousa, S.; Rocha-Santos, T.; Silva, J.P.; Sousa Lobo, J.M.; Costa, P.; Amaral, M.H.; et al. "Influence of l-cysteine, oxygen and relative humidity upon survival throughout storage of probiotic bacteria in whey protein-based microcapsules". International Dairy Journal 21 11 (2011): 869-876. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051590355&partnerID=MN8TOARS.
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  105. Salústio, P.J.; Cabral-Marques, H.M.; Costa, P.C.; Pinto, J.F.. "Comparison of ibuprofen release from minitablets and capsules containing ibuprofen: ß-Cyclodextrin complex". European Journal of Pharmaceutics and Biopharmaceutics 78 1 (2011): 58-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953163698&partnerID=MN8TOARS.
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    10.1111/j.1471-0307.2010.00627.x
  107. Sarraguça, M.C.; Cruz, A.V.; Amaral, H.R.; Costa, P.C.; Lopes, J.A.. "Comparison of different chemometric and analytical methods for the prediction of particle size distribution in pharmaceutical powders". Analytical and Bioanalytical Chemistry 399 6 (2011): 2137-2147. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951722683&partnerID=MN8TOARS.
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  109. Oliveira, S.M.; Almeida, I.F.; Costa, P.C.; Barrias, C.C.; Ferreira, M.R.P.; Bahia, M.F.; Barbosa, M.A.. "Characterization of polymeric solutions as injectable vehicles for hydroxyapatite microspheres". AAPS PharmSciTech 11 2 (2010): 852-858. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954819260&partnerID=MN8TOARS.
    10.1208/s12249-010-9447-3
  110. Ferreira, M.O.; Costa, P.C.; Bahia, M.F.. "Effect of São Pedro do sul thermal water on skin irritation". International Journal of Cosmetic Science 32 3 (2010): 205-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951973654&partnerID=MN8TOARS.
    10.1111/j.1468-2494.2010.00527.x
  111. Sarraguça, M.C.; Cruz, A.V.; Soares, S.O.; Amaral, H.R.; Costa, P.C.; Lopes, J.A.. "Determination of flow properties of pharmaceutical powders by near infrared spectroscopy". Journal of Pharmaceutical and Biomedical Analysis 52 4 (2010): 484-492. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950368292&partnerID=MN8TOARS.
    10.1016/j.jpba.2010.01.038
  112. Almeida, I.F.; Costa, P.C.; Bahia, M.F.. "Evaluation of functional stability and batch-to-batch reproducibility of a castanea sativa leaf extract with antioxidant activity". AAPS PharmSciTech 11 1 (2010): 120-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950915916&partnerID=MN8TOARS.
    10.1208/s12249-009-9360-9
  113. Pena Ferreira, M.R.; Costa, P.C.; Bahia, F.M.. "Efficacy of anti-wrinkle products in skin surface appearance: A comparative study using non-invasive methods". Skin Research and Technology 16 4 (2010): 444-449. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650458977&partnerID=MN8TOARS.
    10.1111/j.1600-0846.2010.00458.x
  114. Almeida, I.F.; Fernandes, E.; Lima, J.L.F.C.; Costa, P.C.; Bahia, M.F.. "In vitro protective effect of hypericum androsaemum extract against oxygen and nitrogen reactive species". Basic and Clinical Pharmacology and Toxicology 105 4 (2009): 222-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349115519&partnerID=MN8TOARS.
    10.1111/j.1742-7843.2009.00458.x
  115. Almeida, I.F.; Fernandes, E.; Lima, J.L.F.C.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Costa, P.C.; Bahia, M.F.. "Oxygen and nitrogen reactive species are effectively scavenged by eucalyptus globulus leaf water extract". Journal of Medicinal Food 12 1 (2009): 175-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-64949116013&partnerID=MN8TOARS.
    10.1089/jmf.2008.0046
  116. Almeida, I.F.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Pereira, T.M.; Amaral, M.H.; Costa, P.C.; Bahia, M.F.. "In vivo skin irritation potential of a Castanea sativa (chestnut) leaf extract, a putative natural antioxidant for topical application". Basic and Clinical Pharmacology and Toxicology 103 5 (2008): 461-467. http://www.scopus.com/inward/record.url?eid=2-s2.0-53949097828&partnerID=MN8TOARS.
    10.1111/j.1742-7843.2008.00301.x
  117. Almeida, I.F.; Fernandes, A.R.; Fernandes, L.; Pena Ferreira, M.R.; Costa, P.C.; Bahia, M.F.. "Moisturizing effect of oleogel/hydrogel mixtures". Pharmaceutical Development and Technology 13 6 (2008): 487-494. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949151932&partnerID=MN8TOARS.
    10.1080/10837450802282447
  118. Oliveira, S.M.; Barrias, C.C.; Almeida, I.F.; Costa, P.C.; Pena Ferreira, M.R.; Bahia, M.F.; Barbosa, M.A.. "Injectability of a bone filler system based on hydroxyapatite microspheres and a vehicle with in situ gel-forming ability". Journal of Biomedical Materials Research - Part B Applied Biomaterials 87 1 (2008): 49-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449123139&partnerID=MN8TOARS.
    10.1002/jbm.b.31066
  119. Almeida, I.F.; Fernandes, E.; Lima, J.L.F.C.; Costa, P.C.; Bahia, M.F.. "Protective effect of Castanea sativa and Quercus robur leaf extracts against oxygen and nitrogen reactive species". Journal of Photochemistry and Photobiology B: Biology 91 2-3 (2008): 87-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-43549108834&partnerID=MN8TOARS.
    10.1016/j.jphotobiol.2008.02.001
  120. Almeida, I.F.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Pereira, T.M.; Amaral, M.H.; Costa, P.C.; Bahia, M.F.. "Oak leaf extract as topical antioxidant: Free radical scavenging and iron chelating activities and in vivo skin irritation potential". BioFactors 33 4 (2008): 267-279. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649783674&partnerID=MN8TOARS.
    10.1002/biof.5520330403
  121. Almeida, I.F.; Fernandes, E.; Lima, J.L.F.C.; Costa, P.C.; Fernanda Bahia, M.. "Walnut (Juglans regia) leaf extracts are strong scavengers of pro-oxidant reactive species". Food Chemistry 106 3 (2008): 1014-1020. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548488742&partnerID=MN8TOARS.
    10.1016/j.foodchem.2007.07.017
  122. Vasconcelos, Teofilo; Sarmento, Bruno; Costa, Paulo. "ChemInform Abstract: Solid Dispersions as Strategy to Improve Oral Bioavailability of Poor Water-Soluble Drugs". ChemInform 39 25 (2008): http://dx.doi.org/10.1002/chin.200825272.
    10.1002/chin.200825272
  123. Vasconcelos, T.; Sarmento, B.; Costa, P.. "Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs". Drug Discovery Today 12 23-24 (2007): 1068-1075. http://www.scopus.com/inward/record.url?eid=2-s2.0-36549042006&partnerID=MN8TOARS.
    10.1016/j.drudis.2007.09.005
  124. Lopes, C.M.; Sousa Lobo, J.M.; Pinto, J.F.; Costa, P.C.. "Compressed matrix core tablet as a quick/slow dual-component delivery system containing ibuprofen". AAPS PharmSciTech 8 3 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-35148838685&partnerID=MN8TOARS.
    10.1208/pt0803051
  125. Lopes, C.M.; Lobo, J.M.; Pinto, J.F.; Costa, P.C.. "Compressed matrix core tablet as a quick/slow dual-component delivery system containing ibuprofen.". AAPS PharmSciTech 8 3 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-35348839011&partnerID=MN8TOARS.
    10.1208/pt0803076
  126. Lopes, C.M.; Lobo, J.M.S.; Pinto, J.F.; Costa, P.. "Compressed mini-tablets as a biphasic delivery system". International Journal of Pharmaceutics 323 1-2 (2006): 93-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748693882&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2006.05.063
  127. Lopes, C.M.; Manuel, J.; Lobo, S.; Costa, P.; Pinto, J.F.. "Directly compressed mini matrix tablets containing ibuprofen: Preparation and evaluation of sustained release". Drug Development and Industrial Pharmacy 32 1 (2006): 95-106. http://www.scopus.com/inward/record.url?eid=2-s2.0-32344433918&partnerID=MN8TOARS.
    10.1080/03639040500388482
  128. Lopes, C.M.; Lobo, José Manuel Sousa; Costa, Paulo. Corresponding author: Lopes, C.M.. "Formas farmacêuticas de liberação modificada: polímeros hidrifílicos". Revista Brasileira de Ciências Farmacêuticas 41 2 (2005): 143-154. http://dx.doi.org/10.1590/s1516-93322005000200003.
    Published • 10.1590/s1516-93322005000200003
  129. Lopes, C.M.; Lobo, J.M.S.; Costa, P.. "Modified release of drug delivery systems: Hydrophilic polymers,Formas farmacêuticas de liberação modificada: Polímeros hidrifílicos". Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences 41 2 (2005): 143-154. http://www.scopus.com/inward/record.url?eid=2-s2.0-26244453504&partnerID=MN8TOARS.
  130. Costa, P.; Sousa Lobo, J.M.. "Evaluation of mathematical models describing drug release from estradiol transdermal systems". Drug Development and Industrial Pharmacy 29 1 (2003): 89-97. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037273037&partnerID=MN8TOARS.
    10.1081/DDC-120016687
  131. Da Costa, P.J.C.. "In vitro evaluation of the lyoequivalence of pharmaceutical formulations,Avaliação in vitro da lioequivalência de formulações farmacêuticas". Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences 38 2 (2002): 141-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036557790&partnerID=MN8TOARS.
  132. Costa, P.. "An alternative method to the evaluation of similarity factor in dissolution testing". International Journal of Pharmaceutics 220 1-2 (2001): 77-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035806261&partnerID=MN8TOARS.
    10.1016/S0378-5173(01)00651-2
  133. Costa, P.; Lobo, J.M.S.. "Influence of dissolution medium agitation on release profiles of sustained-release tablets". Drug Development and Industrial Pharmacy 27 8 (2001): 811-817. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034752807&partnerID=MN8TOARS.
    10.1081/DDC-100107244
  134. Costa, P.; Sousa Lobo, J.M.. "Divisability of diltiazem matrix sustained-release tablets". Pharmaceutical Development and Technology 6 3 (2001): 343-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034923485&partnerID=MN8TOARS.
    10.1081/PDT-100002616
  135. Costa, P.; Sousa Lobo, J.M.. "Modeling and comparison of dissolution profiles". European Journal of Pharmaceutical Sciences 13 2 (2001): 123-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035073301&partnerID=MN8TOARS.
    10.1016/S0928-0987(01)00095-1
  136. Costa, P.; Sousa Lobo, J.M.. "Avaliação das características de libertação de fármacos a partir de formas sólidas". Revista Portuguesa de Farmacia 50 1 (2000): 41-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0039923566&partnerID=MN8TOARS.
  137. Costa, P.; Amaral, H.; Sousa Lobo, J.M.. "Dissolution characteristics of divisible tablets". S.T.P. Pharma Sciences 10 5 (2000): 373-377. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033775662&partnerID=MN8TOARS.
  138. Costa, P.; Lobo, J.M.S.. "Formas farmacêuticas de libertação modificada". Revista Portuguesa de Farmacia 49 4 (1999): 181-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-0013310982&partnerID=MN8TOARS.
  139. Costa, P.; Amaral, H.; Ferreira, D.C.; Lobo, J.M.S.. "Divisibilidade de comprimidos". Revista Portuguesa de Farmacia 48 1 (1998): 13-22. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347504442&partnerID=MN8TOARS.
  140. Ferreira, D.C.; Costa, P.; Sousa Lobo, J.M.. "Effect of pH on the release and permeation of diazepam from sustained-release dosage forms". Pharmaceutical Sciences 3 4 (1997): 171-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031416595&partnerID=MN8TOARS.
  141. Costa, P.; Ferreira, D.C.; Morgado, R.; Sousa Lobo, J.M.. "Design and evaluation of a lorazepam transdermal delivery system". Drug Development and Industrial Pharmacy 23 10 (1997): 939-944. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030851035&partnerID=MN8TOARS.
  142. Ferreira, D.C.; Costa, P.; Morgado, R.; Sousa Lobo, J.M.. "Evaluation of an in vitro dissolution and permeation apparatus for oral solid pharmaceutical dosage forms". Drug Development and Industrial Pharmacy 23 4 (1997): 387-392. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030901193&partnerID=MN8TOARS.
  143. Lima, C.M.; Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Comprimidos de dipirona obtidos por diferentes processos de granulação: Estudo comparativo das velocidades de dissolução e permeação in-vitro". Revista Portuguesa de Farmacia 47 3 (1997): 95-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345846982&partnerID=MN8TOARS.
  144. Lima, C.M.; Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Comprimidos de dipirona obtidos por diferentes processos de granulação: Estudo comparativo das velocidades de dissolução e permeação in-vitro". Revista Portuguesa de Farmacia 47 3 (1997): 95-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345846982&partnerID=MN8TOARS.
  145. Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Determination of drug release profiles of nitroglycerin transdermal therapeutic systems,Nitroglicerina em Sistemas de Libertação Transdérmica - Determinação da velocidade de libertação". Revista Portuguesa de Farmacia 46 1 (1996): 2-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542786133&partnerID=MN8TOARS.
  146. Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Lorazepam in the transdermal releasing system. Selection and study of plasticizers,LORAZEPAM EM SISTEMAS DE LIBERTACAO TRANSDERMICA - SELECCAO E ESTUDO DO PLASTIFICANTE". Revista Portuguesa de Farmacia 45 2 (1995): 84-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029070335&partnerID=MN8TOARS.
  147. Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Lorazepam in the transdermal releasing system. Influence of agitation, temperature and thickness of the film on the release of lorazepam 'in vitro',LORAZEPAM EM SISTEMAS DE LIBERTACAO TRANSDERMICA. INFLUENCIA DA AGITACAO, DA TEMPERATURA E DA ESPESSURA DA PELICULA NA CEDENCIA IN VITRO DE LORAZEPAM". Revista Portuguesa de Farmacia 45 2 (1995): 79-83. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029034377&partnerID=MN8TOARS.
  148. Costa, P.; Ferreira, D.C.; Sousa Lobo, J.M.. "Transdermal drug delivery systems,SISTEMAS DE LIBERTACAO TRANSDERMICA". Revista Portuguesa de Farmacia 43 3 (1993): 19-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027504869&partnerID=MN8TOARS.
  149. Costa, P.; Ferreira, D.C.; Lobo, J.M.S.. "Lyoavailability of lorazepam in transdermal drug delivery systems,LIODISPONIBILIDADE DO LORAZEPAM EM SISTEMAS DE LIBERTACAO TRANSDERMICA". Revista Portuguesa de Farmacia 43 3 (1993): 47-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027525401&partnerID=MN8TOARS.
Magazine article
  1. Silva, Ana Margarida; Costa, Paulo; delerue-matos, C; Rodrigues, Francisca. "Frutos e subprodutos de Actinidia arguta como fonte de compostos bioativos para diferentes indústrias", Revista Tecnoalimentar, 2023
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019 - Current Targeting HER2- positive gastric and esophageal cancers with functionalized lipids nanoparticles of docetaxel: development and characterization of thermosensitive in situ gels for intratumoral drug delivery
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current Synergic approach to the treatment of glioblastoma through a novel xanthone-polymersome system
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current From soil to skin: Eco-friendly extract from kiwiberry leaves for prevention and treatment of skin aging process
Co-supervisor
 Química Sustentável (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current Desenvolvimento Farmacêutico de medicamentos semissólidos baseado no conceito Quality by design
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - Current Lipid-based nanocarriers for enhancement of blood-brain barrier permeability in the treatment of amyotrophic lateral sclerosis
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - Current Development of a prolonged-release oral system for palliative treatment of oral mucositis induced by cancer treatments
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2019 Estudo sobre a preparação e estabilidade de medicamentos manipulados nos serviços farmacêuticos hospitalares
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2019 Response surface evaluation of Subcritical Water Extraction conditions of Castanea sativa shells bioactive compounds: A cosmetic application
Co-supervisor
 Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2019 Estudos de estabilidade de fórmulas magistrais oftálmicas
Co-supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2019 Estudo de estabilidade de uma suspensão oral de bosentano para o tratamento da hipertensão arterial pulmonar em pediatria
Co-supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2019 Extração de cascas de Castanea sativa por Técnica Assistida de Ultrassons: Caracterização química e aplicação cosmética
Supervisor
 Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2018 Nanopartículas poliméricas de pentamidina, uma estratégia no tratamento da leishmaniose
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2018 Películas bucais mucoadesivas com fluconazol
Supervisor
 Tecnologia Farmacêutica
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2017 Development of a proliposome formulation as a drug carrier for a novel antitumor drug
Supervisor
 Química Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016 Desenvolvimento de veículos destinados à preparação de suspensões para uso veterinário
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015 Production of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) containing antitumoral drug (saquinavir)
Supervisor
 Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2015 Desenvolvimento de Nanopartículas lipídicas com Paclitaxel para tratamento do Glioma
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2014 Estudo de um produto cosmético antirrugas utilizando parâmetros biométricos da pele com recurso a técnicas não-invasivas
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2009 Desenvolvimento de um sistema semi-sólido contendo fitocompostos captadores de espécies reactivas
Co-supervisor
 Tecnologia Farmacêutica (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2008 Estudo dos efeitos cutâneos da água termal de S. Pedro do Sul por biometria cutânea
Co-supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2006 - 2008 Solid Dispersions Containing Ibuprofen
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2006 Libertação modificada em sistemas matriciais sólidos contendo ibuprofeno
Co-supervisor
 Tecnologia Farmacêutica (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2003 Teoria da percolação aplicada à produção de comprimidos
Supervisor
 Tecnologia Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Committee member

Activity description
Role 		Institution / Organization
2021 - Current Responsável do Laboratório de Tecnologia Farmacêutica da Faculdade de Farmácia da Universidade do Porto
Director
 Universidade do Porto Faculdade de Farmácia, Portugal
2019/04 - Current Diretor do Mestrado em Tecnologia Farmacêutica
Director
 Universidade do Porto Faculdade de Farmácia, Portugal
2018/12 - Current Presidente do Conselho de Representantes da Faculdade de Farmácia da Universidade do Porto
President / Vice-president
 Universidade do Porto Faculdade de Farmácia, Portugal
2018/12 - Current Senado da Universidade do Porto
Member
 Universidade do Porto, Portugal
2016/01 - Current É membro do Conselho Científico da Faculdade de Farmácia da Universidade do Porto
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2016 - Current Vice-presidente da Comissão de Ética para a Saúde da Inovapotek - Contract Research Organization (Parque de Ciência e Tecnologia da Universidade do Porto - UPTEC)
President / Vice-president
 Inovapotek Pharmaceutical Research and Development Lda, Portugal
2016/11 - 2020/10 Conselho Científico e Editorial U.Porto Edições
Member
 Universidade do Porto, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2013 - Current Perito para o Grupo de Avaliação dos Medicamentos Veterinários (GAMV) da Direção Geral de Alimentação e Veterinária (DGAV) - despacho nº 24/G/2013 do Diretor geral da DGAV.
Specialist
 Direcção-Geral de Alimentação e Veterinária, Portugal Direcção-Geral de Alimentação e Veterinária