Identification
Personal identification
- Full name
- Madalena Costa Santos
Citation names
- Santos, Madalena
Author identifiers
- Ciência ID
- FA13-C72E-61EA
- ORCID iD
- 0000-0002-1101-3515
Education
Degree | Classification | |
---|---|---|
2014/07/04
Concluded
|
Especialista na área de Anatomia Patológica Citológica e Tanatológica (Título de especialista)
Instituto Politécnico do Porto, Portugal
|
|
2014 - 2014
Concluded
|
A hands-on approach to cell and tissue culture-from cell isolation (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
|
|
2012 - 2012
Concluded
|
Workshop Necropsy: Laboratory mice and rats (Outros)
Universidade do Porto- Instituto de biologia molecular e celular, Portugal
|
|
2011 - 2011
Concluded
|
I Workshop on Cancer Research: biological and molecular basis (Outros)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
|
2006/04/10 - 2006/05/02
Concluded
|
Curso de Ciências de Animais de Laboratório - Categoria C (Outros)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
|
2005 - 2005
Concluded
|
1st Workshop on advanced light microscopy and flow citometry (Outros)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
|
2003 - 2004
Concluded
|
Ciências Médico-Legais (Especialização pós-licenciatura)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
16 |
2003 - 2003
Concluded
|
Curricular Unit of Systematic Anatomy I (Outros)
Universidade do Porto - Instituto de Ciências Biomédicas Abel Salazar, Portugal, Portugal
|
|
2001/03/05
Concluded
|
Anatomia Patológica, Citológica e Tanatológica (Licenciatura)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
17 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
1998/09/01 - 2002 | Research Assistant (Research) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2018 - Current | Invited Adjunct Teacher (Polytechnic Teacher) | Instituto Politécnico do Porto, Portugal |
2016 - 2018 | Invited Assistant (Polytechnic Teacher) | Instituto Politécnico do Porto, Portugal |
2013 - 2016 | Assistant (Polytechnic Teacher) | Instituto Politécnico do Porto Escola Superior de Saúde, Portugal |
Other Careers
Category Host institution |
Employer | |
---|---|---|
2002/03/22 - Current | Técnico Principal (Técnico de Diagnóstico e Terapêutica - Técnico de Anatomia Patológica, Citológica e Tanatológica) | Universidade do Porto - Instituto de Ciências Biomédicas Abel Salazar, Portugal, Portugal |
Universidade do Porto - Instituto de Ciências Biomédicas Abel Salazar, Portugal, Portugal |
Projects
Contract
Designation | Funders | |
---|---|---|
2019/01/01 - Current | Multidisciplinary Unit for Biomedical Resaerch
UID/Multi/00215/2019
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2011/08/01 - Current | The role of the vagus nerve and brainstem pathways in the mechanisms of gastro-intestinal hormones induced weight loss
Technical development
|
Fundação para a Ciência e a Tecnologia |
2022/01/01 - 2024/12/31 | Unravelling the molecular signatures and mechanisms associated with obesity surgery failure
PTDC/MEC-CIR/3615/2021
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal Centro Hospitalar de Entre o Douro e Vouga EPE, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2022/09/30 | Exploring the role of epigenomic and adipocyte-associated signals in metabolic dysfunction
PTDC/MEC-MET/32151/2017
Universidade do Porto, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2018/10/01 - 2022/09/30 | Early molecular bases for the diagnosis and treatment of adrenocortical tumors in the era of personalized medicine
PTDC/MEC-ONC/31384/2017
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2012/04/02 - 2015/10/01 | Rabbit Haemorrhagic Disease (RHD): What are the molecular and cellular mechanisms that make young rabbits resistant to lethal
calicivirus infection?
PTDC/CVT/122905/2010
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2012/04/02 - 2014/12/01 | Role of the adipose tissue in the host immune response to N. caninum infection
PTDC/CVT/122777/2010
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/04/01 - 2014/09/30 | GIANTCELL - The modulation of macrophages to resolve inflammatory reactions to biomaterials through the induction of the M2
phenotype
PTDC/SAU-BMA/113030/2009
Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/01/01 - 2013/12/31 | Strategic Project - UI 215 - 2011-2012
PEst-OE/SAU/UI0215/2011
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal Centro Hospitalar Universitário de Santo António, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2007/12/01 - 2011/11/30 | Rabbit Haemorrhagic Disease (RHD): Molecular Biology of Resistance and Transmission of Calicivirus.
PTDC/CVT/66656/2006
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2007/10/01 - 2011/09/29 | Changes in gastro-intestinal hormones after weight loss induced by bariatric surgery with gastric banding
PTDC/SAU-OSM/68204/2006
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2006 - 2009 | Se-induced prevention of Hg toxicity
Technical development
|
Concluded
|
2005/07/24 - 2008/06/30 | Rabbit Haemorrhagic Disease (RHD): Why are young rabbits resistant to the same viral infection that kills adult rabbits?
POCI/CVT/59943/2004
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Unidade Multidisciplinar de Investigação Biomédica, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2003 - 2007 | Vibroacoustic disorder: changes in pleura.
FCT. POCTI/CBO/40915/2001
Technical development
|
|
2003 - 2007 | Inhalation of atmospheric particles of tungsten: immunopathology of hard metal disease of the lung.
FCT. POCTI/36188/BSE/2000
Technical development
|
Outputs
Publications
Conference paper |
|
Conference poster |
|
Journal article |
|
Other
Other output |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/02/02 | Glutaminolysis pathway has an active role in adrenocortical carcinoma pathophysiology. | Congresso Português de Endocrinologia- 75ª Reunião Anual da SPEDM |
2021/09 | Magnesium sulphate-doped fibrinogen scaffolds modulate macrophage polarization | 31st Conference of the European Society for Biomaterials
European Society for Biomaterials (PORTO, Portugal)
|
2020 | A enzima 11b-hidroxilase como marcador para o diagnóstico dos tumores adrenocorticais funcionantes. | Portuguese Congress of Endocrinology, SPEDM |
2019/12/13 | GAPDH maternal vaccination affects brain's myeloid cells of their offspring. | Meeting of Young Researchers (IJUP)
(Porto, Portugal)
|
2019 | Differential GIP/GLP-1 intestinal cell distribution in diabetics; yields distinctive rearrangements depending on Roux-en-Y biliopancreatic limb length. | 53ª Meeting of the Portuguese Anatomic Society |
2017 | Roux-en-Y gastric bypass with long biliopancreatic limb results in improved diabetes control that could be explained by the distinctive incretin cell distribution. | Second EASD Incretin Study Group Meeting
(Italy)
|
2016/04/30 | Distinctive incretin secretionig cell distribution at different intestinal limb of gastric bypass surgery that could yield diverse outcomes in the endocrine profile. | 50ª Reunião Científica da Sociedade Anatómica Portuguesa (SAP) e 3ª Reunião Científica da Associação Anatómica Portuguesa
(AAP)
(Braga, Portugal)
|
2016/04/01 | Da doação à disseção. | VI Simpósio Técnico de Anatomia Patológica-Novos Temas Novos Caminhos,
(Porto, Portugal)
|
2016 | Vagally mediated exposure to chronic GLP-1 may influence leptin production without changing pancreatic morphology. | |
2016 | Chronic GLP-1 does not alter general pancreactic morphology but may reduce alpha-cell division rate. | |
2015/11/19 | In vivo models in cancer research. | II International Health Congress Promoting health technologies.from diagnosis to intervention.
(Porto, Portugal)
|
2015/10/09 | Modulation of the inflammatory response to chitosan thourgh m2macrofage polarization using pro-resolution mediators. | ESF-EMBO Conference on interation between the immune system and nanomaterials: safety and medical exploitation
(Pultusk, Poland)
|
2015 | Adipocyte secreted factors of obese individuals increase the metabolic activity of the adrenocortical tumor cells. | UMIB Summit
(Porto, Portugal)
|
2015 | Caracterização dos efeitos de dois antagonistas dos receptores de mineralocorticóides na morfologia da supra-renal. | Congresso da Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo
(Funchal , Portugal)
|
2015 | Characterization of the effects of two mineralocorticoid receptor antagonists on the morphology of the adrenal cortex. | |
2014 | GLP-1 secreting cells distribution along the human small gut may explain glycemic improvement after gastric bypass surgery. | Portuguese Congress of Endocrinology
Portuguese Society of Endocrinology, Diabetes and Metabolism
|
2013 | The effects of truncal vagotomy in energy homeostasis and acute response to glp-1. | World Diabetes Congress
(Melbourn, Australia)
|
2013 | Tissue microarray technology and immunohistochemistry for characterization of the relative distribution of neuroendocrine cells in the human small intestine. | II Congress of the European Joint Congress of Clinical Anatomy
(Lisboa, Portugal)
|
2012 | Insulin prevents leptin inhibition of RM1 prostate cancer cell growtht;. 2 nd Congress of ALGEDM - Luso-Galician Association of Endocrinology, Diabetes and Metabolism, 2012. Portugal. | Congress of ALGEDM - Luso-Galician Association of Endocrinology, Diabetes and Metabolism, 2012. Portugal. |
2009 | Museu anatómico: da constituição à recuperação. | II Simpósio em Anatomia Patológica
(Vila Nova de Gaia, Portugal)
|
2004 | Acão antitunoral da inflamação granulócitica no melanoma experimental do ratinho. | X Jornadas Portuguesas de Informação em Saúde
(Porto, Portugal)
|
2000 | Mast, a conserved microtubule-associated protein required for mitotic spindle organisation. | XII Congresso Nacional de Bioquímica, Póvoa de Varzim
(Póvoa de Varzim, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2020 - 2021 | Associação Inflamação/Fibrose no crescimento tumoral do melanoma
Supervisor
|
Ciências Biomédicas Laboratoriais (Degree)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2020 - 2021 | Doenças oftálmicas: o ratinho como modelo de estudo
Co-supervisor
|
Ciências Biomédicas Laboratoriais (Degree)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2017 - 2018/06 | Evaluation of Steroidogenic Proteins Expression in Adrenocortical Tumors
(Avaliação da Expressão das Proteínas Esteroidogénicas nos Tumores Adrenocorticais)
Co-supervisor
|
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2017 - 2018 | Characterization of ACTH-producing cells in adrenocortical macronodular hyperplasia (Caracterização das célulasprodutoras
de ACTH nas hiperplasias macronodulares adrenocorticais)
Co-supervisor
|
Universidade do Porto Faculdade de Ciências, Portugal
|
2017 - 2017 | Detection of P-Glycoprotein Expression in Rat Normal Live rand Small Intestine .
Co-supervisor
|
Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
|
2014 - 2015 | Modelos Vasculares de Rato no Estudo de Metodologias de Colheita de Sangue
Supervisor
|
Degree in Anatomical Pathology, Cytology and Thanatology (Degree)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2013 - 2014 | Characterization of the effects mineralocorticoid receptor antagonists on the adrenal gland morphology (Caraterização dos
efeitos dos antagonistas dos recetores dos mineralocorticoides na morfologia da glândula supra- renal)
Co-supervisor
|
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
2012 - 2013 | Técnicas de Tissue Microarray e Imunohistoquímica na caraterização da distribuição relativa de células neuroendrócrinas no
jejuno-íleo.
Co-supervisor
|
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
|
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2023/06/22 - 2023/06/23 | The 2nd meeting of Portuguese Network on Extracellular Vesicles included 2 plenaries, 4 invited talks from international and national speakers, and 16 oral presentations and poster sessions regarding the research on extracellular vesicles in Portugal. |
Universidade NOVA de Lisboa NOVA Medical School, Portugal
|
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2016 - Current | Histotecnologia | (Licenciatura) | Instituto Politécnico do Porto Escola Superior de Saúde, Portugal |
Distinctions
Award
2023 | Best poster communication of Mechanisms of disease and predictive markers at UMIB Summit 2023 for the study "GLS2 plays a role in adrenocortical carcinoma pathophysiology" |
2022 | Honorable mention at the 26º Portuguese Congress of obesity, for the study "Perfil Metabólico do tecido adiposo visceral em pacientes com diferentes classes de obesidade" |
2022 | Best basic research award at the Portuguese Congress of Endocrinology, for the study "ANG-TIE pathway role in adrenocortical tumors angiogenesis" |
2019 | Second place at the contest for the best research study in Morphological Sciences with the work "Differential GIP/GLP-1 intestinal cell distribution in diabetics' ; yields distinctive rearrangements depending on Roux-en-Y biliopancreatic limb length" |
2013 | Manuel Pinheiro Hargreaves Award in the XIX Post Graduate Course of Endocrinology, Diabetes and Metabolism, for the study "Immunohistochemistry markers in the differential diagnosis of adrenocortical tumors." |
2012 | Best panel Communication in 2nd Congress of the Luso Galician Association of Endocrinology, Diabetes and Metabolism for the work ;Insulin prevents leptin inhibition of RM1prostate cancer cell growth. |