Tiago Gil Oliveira (FB19-641C-5859)

Curriculum Vitae

Tiago Gil Oliveira

Tiago Gil Oliveira was a student in the joint MD/PhD program of the University of Minho, Portugal and Columbia University, NYC, USA. He performed his PhD studies at Columbia University, between 2007 and 2010, under the supervision of Prof. Gilbert Di Paolo and co-supervision by Prof. Nuno Sousa, and his MD studies at University of Minho. While studying the role of lipid signaling in Alzheimer’s disease pathogenesis, he showed that the ablation of the lipid-modulating enzyme, phospholipase D2, was protective in different Alzheimer’s disease models. In 2011 he started his post-graduate studies as Assistant Professor at the School of Medicine, University of Minho, where he teaches Anatomy to medical students. While in Minho he expanded his research interests to the study of mood disorders. Using an unbiased lipidomic approach, he showed that specific lipid signaling pathways were altered in a chronic stress model, unraveling new potential therapeutic targets. In parallel with his academic work he continued his medical career. He is currently a Neuroradiologist at Hospital de Braga and he is now using lipidomic approaches associated with brain imaging to study neurodegenerative diseases.

Read full resume ↓

Identification

Personal identification

Full name: Tiago Gil Oliveira

Citation names

Oliveira, Tiago Gil

Author identifiers

Ciência ID: FB19-641C-5859
ORCID iD: 0000-0003-0509-0562

Knowledge fields

Medical and Health Sciences - Basic Medicine - Neurosciences
Medical and Health Sciences - Basic Medicine - Pathology
Medical and Health Sciences - Basic Medicine - Pathology
Medical and Health Sciences - Clinical Medicine - Radiology, Nuclear Medicine and Medical Imaging
Natural sciences - Biological Sciences - Biochemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2013/01/01 - 2018/04/17 Concluded	Especialidade Médica em Neurorradiologia (Título de especialista) Hospital de Braga, Portugal	19.3
2011 Concluded	LICENCIATURA EM MEDICINA COM MESTRADO INTEGRADO (Curso de Especialização Tecnológica) Universidade do Minho Escola de Medicina, Portugal "N/A" (THESIS/DISSERTATION)	16
2010 Concluded	Medicina (Doutoramento) Major in Especialidade: Medicina Universidade do Minho, Portugal "The Role Phospholipase D2 in Alzheirmer`s Disease" (THESIS/DISSERTATION)

Affiliation

Teaching in Higher Education

	Category Host institution	Employer
2022/09/01 - Current	Associate Professor (University Teacher)	Universidade do Minho, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/01/01 - 2022/09/01	Assistant Professor (University Teacher)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2011 - 2020/01/01	Invited Assistant Professor (University Teacher)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Others

	Category Host institution	Employer
2018/04/18 - Current	Neuroradiologist	Hospital de Braga, Portugal

2013/01/01 - 2018/04/17	Neuroradiology Resident	Hospital de Braga, Portugal

2012/01/01 - 2012/12/31	General Resident	Hospital de Braga, Portugal

2002/09/01 - 2011/07/01	Medical Student - MD/PhD program	Universidade do Minho, Portugal

2007/09/01 - 2010/12/07	PhD student - MD/PhD program	Columbia University, United States

Projects

Grant

	Designation	Funders
2023/03/01 - 2026/02/28	The role of phospholipase D2 in Alzheimer’s disease 2022.05366.PTDC Principal investigator Fundação para a Ciência e a Tecnologia, Portugal	Ongoing
2023/01/01 - 2024/12/31	Brain imaging determinants of Alzheimer’s disease neuropathology - Principal investigator Fundação Amélia de Mello, Portugal	Ongoing
2021/03 - 2023/02	Studying the differential impact of chronic stress on the longitudinal hippocampal axis by MRI 29817/20	Brain and Behavior Research Foundation
2020/01/01 - 2021/12/31	The role of interneurons in spatial memory 320/18 Principal investigator Universidade do Minho, Portugal	Fundação Bial Ongoing
2015/04 - 2017/09	The impact of lipid signaling modulation in cognition 253/14	Fundação Bial

Contract

	Designation	Funders
2021/01/01 - 2025/12/31	ICVS/3B¿s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos LA/P/0050/2020 10.54499/LA/P/0050/2020 UID/Multi/50026/2019 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017/02/01 - 2021/04/30	Redes sinápticas e abordagens compreensivas de medicina personalizada em doenças neurocomportamentais ao longo da vida SAICTPAC/0010/2015 Universidade de Aveiro, Portugal Universidade do Minho, Portugal Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2012/05/06 - 2015/10/05	A influência de interacções neurónio-glia na progressão de patologias induzidas pelo stress PTDC/SAU-NSC/118194/2010 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2012/04/01 - 2015/07/31	The role of brain lipid metabolism in the modulation of chronic stress effects PTDC/SAU-NMC/118971/2010 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/01/01 - 2012/12/31	Strategic Project - LA 26 - 2011-2012 PEst-C/SAU/LA0026/2011 Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Other

	Designation	Funders
2012/04/01 - 2015/08/31	Deciphering the role of Aβ and TAU among neuronal subpopulations in Alzheimer´s disease network malfunction. PTDC/SAU-NSC/120590/2010 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book	Silva, F.S.; Oliveira, T.G.; Alves, V.. Study of MRI-Based Biomarkers on Patients with Cerebral Amyloid Angiopathy Using Artificial Intelligence. 2021. 10.1007/978-3-030-72657-7_18
Conference abstract	P. Ribeiro, Inês; Rosana Aves; Morais-Ribeiro, Rafaela; Paiva, Sandra; Oliveira, Tiago Gil. Corresponding author: Oliveira, Tiago Gil. "Expression of Mammalian PLD1 and PLD2 in the Yeast Model". 2022. 10.21814/1822.75916
Conference poster	Francisca Vaz Bravo; DA SILVA, JORGE D.; Chan, Robin Barry; Di Paolo, Gilbert; Teixeira-Castro, Andreia; Oliveira, Tiago Gil. "The impact of PLD functional ablation in an Alzheimer's disease Caenorhabditis elegans model". Paper presented in 47th Society for Neuroscience, 2017. Francisca Vaz Bravo; DA SILVA, JORGE D.; Chan, Robin Barry; Di Paolo, Gilbert; Teixeira-Castro, Andreia; Oliveira, Tiago Gil. "The impact of phospholipase D functional ablation in physiology and in disease models in Caenorhabditis elegans". Paper presented in XV Meeting of the Portuguese Society for Neuroscience, 2017.
Journal article	Francisco C. Almeida; Kalicharan Patra; Andreas Giannisis; Anezka Niesnerova; Renu Nandakumar; Ewa Ellis; Tiago Gil Oliveira; Henrietta M. Nielsen. "APOE genotype dictates lipidomic signatures in primary human hepatocytes". Journal of Lipid Research (2024): https://doi.org/10.1016/j.jlr.2024.100498. 10.1016/j.jlr.2024.100498 Ferreira, J.P.; Leite-Moreira, A.; da Costa-Pereira, A.; Soares, A.J.; Robalo-Cordeiro, C.; Jerónimo, C.; Gavina, C.; et al. "Investigator-Led Clinical Research in Portugal: Problem Identification and Proposals for Improvement,Investigação Clínica da Iniciativa do Investigador em Portugal: Identificação de Problemas e Propostas para Melhoria". Acta Medica Portuguesa 36 5 (2023): 305-308. http://www.scopus.com/inward/record.url?eid=2-s2.0-85159552183&partnerID=MN8TOARS. 10.20344/amp.19333 Pinho, J.; Almeida, F.C.; Araújo, J.M.; Machado, Á.; Costa, A.S.; Silva, F.; Francisco, A.; et al. "Sex-Specific Patterns of Cerebral Atrophy and Enlarged Perivascular Spaces in Patients with Cerebral Amyloid Angiopathy and Dementia". AJNR. American journal of neuroradiology 44 7 (2023): 792-798. http://www.scopus.com/inward/record.url?eid=2-s2.0-85164624844&partnerID=MN8TOARS. 10.3174/ajnr.A7900 Calafate, S.; Özturan, G.; Thrupp, N.; Vanderlinden, J.; Santa-Marinha, L.; Morais-Ribeiro, R.; Ruggiero, A.; et al. "Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease". Nature Neuroscience 26 6 (2023): 1021-1031. http://www.scopus.com/inward/record.url?eid=2-s2.0-85159273259&partnerID=MN8TOARS. 10.1038/s41593-023-01325-4 André Miguel Miranda; Archana Ashok; Robin Barry Chan; Bowen Zhou; Yimeng Xu; Laura Beth McIntire; Estela Area-Gomez; et al. "Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice". Translational Psychiatry 12 1 (2022): https://doi.org/10.1038/s41398-022-01881-6. 10.1038/s41398-022-01881-6 Miguel Quintas-Neves; Merilee A. Teylan; Rafaela Morais-Ribeiro; Francisco Almeida; Charles N. Mock; Walter A. Kukull; John F. Crary; Tiago Gil Oliveira. "Divergent magnetic resonance imaging atrophy patterns in Alzheimer's disease and primary age-related tauopathy". Neurobiology of Aging (2022): https://doi.org/10.1016/j.neurobiolaging.2022.04.013. 10.1016/j.neurobiolaging.2022.04.013 Miguel Sá Breda; Ana Sousa Menezes; Tiago Gil Oliveira; Luís Dias. "Influence of Metabolic Syndrome on the Recovery from Idiopathic Sudden Sensorineural Hearing Loss". International Archives of Otorhinolaryngology (2022): https://doi.org/10.1055/s-0041-1741027. 10.1055/s-0041-1741027 Pinho, J.; Araújo, J.M.; Costa, A.S.; Silva, F.; Francisco, A.; Quintas-Neves, M.; Soares-Fernandes, J.; Ferreira, C.; Oliveira, T.G.. "Intracerebral Hemorrhage Recurrence in Patients with and without Cerebral Amyloid Angiopathy". Cerebrovascular Diseases Extra (2021): 15-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100287111&partnerID=MN8TOARS. 10.1159/000513503 Kalinichenko, L.S.; Mühle, C.; Jia, T.; Anderheiden, F.; Datz, M.; Eberle, A.-L.; Eulenburg, V.; et al. "Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects". Molecular Psychiatry 26 12 (2021): 7403-7416. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115835215&partnerID=MN8TOARS. 10.1038/s41380-021-01304-w Oliveira, Tiago Gil; Ifrah, Chloe; Fleysher, Roman; Stockman, Michael; Lipton, Michael L.. "Soccer heading and concussion are not associated with reduced brain volume or cortical thickness". PLOS ONE 15 8 (2020): e0235609. http://dx.doi.org/10.1371/journal.pone.0235609. 10.1371/journal.pone.0235609 van Kruining, Daan; Luo, Qian; van Echten-Deckert, Gerhild; Mielke, Michelle M.; Bowman, Andrew; Ellis, Shane; Oliveira, Tiago Gil; Martinez-Martinez, Pilar. "Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods". Advanced Drug Delivery Reviews (2020): http://dx.doi.org/10.1016/j.addr.2020.04.009. 10.1016/j.addr.2020.04.009 Gago, M.F.; Azevedo, O.; Guimarães, A.; Teresa Vide, A.; Lamas, N.J.; Oliveira, T.G.; Gaspar, P.; et al. "Parkinson's Disease and Fabry Disease: Clinical, Biochemical and Neuroimaging Analysis of Three Pedigrees". Journal of Parkinson's Disease 10 1 (2020): 141-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-85078502643&partnerID=MN8TOARS. 10.3233/JPD-191704 André Miguel Miranda; Francisca Vaz Bravo; Robin B. Chan; Nuno Sousa; Gilbert Di Paolo; Tiago Gil Oliveira. "Differential lipid composition and regulation along the hippocampal longitudinal axis". Translational Psychiatry 9 1 (2019): https://doi.org/10.1038/s41398-019-0478-6. 10.1038/s41398-019-0478-6 Miguel Quintas-Neves; Merilee A. Teylan; Lilah Besser; João Soares-Fernandes; Charles N. Mock; Walter A. Kukull; John F. Crary; Tiago Gil Oliveira. "Magnetic resonance imaging brain atrophy assessment in primary age-related tauopathy (PART)". Acta Neuropathologica Communications (2019): https://doi.org/10.1186/s40478-019-0842-z. 10.1186/s40478-019-0842-z Tabbai, S.; Moreno-Fernández, R.D.; Zambrana-Infantes, E.; Nieto-Quero, A.; Chun, J.; García-Fernández, M.; Estivill-Torrús, G.; et al. "Effects of the LPA1 receptor deficiency and stress on the hippocampal LPA species in mice". Frontiers in Molecular Neuroscience 12 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069514845&partnerID=MN8TOARS. 10.3389/fnmol.2019.00146 Francisca Vaz Bravo; Jorge Da Silva; Robin Barry Chan; Gilbert Di Paolo; Andreia Teixeira-Castro; Tiago Gil Oliveira. "Phospholipase D functional ablation has a protective effect in an Alzheimer’s disease Caenorhabditis elegans model". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-21918-5. 10.1038/s41598-018-21918-5 Miranda, A.M.; Lasiecka, Z.M.; Xu, Y.; Neufeld, J.; Shahriar, S.; Simoes, S.; Chan, R.B.; et al. "Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures". Nature Communications 9 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040774881&partnerID=MN8TOARS. 10.1038/s41467-017-02533-w Tiago Gil Oliveira; João Paulo Soares-Fernandes. "Brain MRI in a patient with classical galactosemia: acute event of unilateral hemispheric cerebral edema". Child's Nervous System 33 11 (2017): 1879-1880. https://doi.org/10.1007/s00381-017-3594-8. 10.1007/s00381-017-3594-8 Oliveira, T.G.; Chan, R.B.; Bravo, F.V.; Miranda, A.; Silva, R.R.; Zhou, B.; Marques, F.; et al. "The impact of chronic stress on the rat brain lipidome". Molecular Psychiatry 21 1 (2016): 80-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951906991&partnerID=MN8TOARS. 10.1038/mp.2015.14 Lamas, Nuno Jorge; Amorim, João Filipe Pinheiro; Almeida, António Manuel Melo Soares; Mendes, Sofia Silva; Martins, Sandra; Teixeira, Pedro Alexandre Leão Araújo Gonçalves; Oliveira, Tiago Gil; et al. "Ensino da Anatomia na Escola de Ciências da Saúde da Universidade do Minho". (2016): http://hdl.handle.net/1822/50986. Miranda, A.M.; Oliveira, T.G.. "Lipids under stress - A lipidomic approach for the study of mood disorders". BioEssays 37 11 (2015): 1226-1235. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944597098&partnerID=MN8TOARS. 10.1002/bies.201500070 Pinto, V.; Costa, J.C.; Morgado, P.; Mota, C.; Miranda, A.; Bravo, F.V.; Oliveira, T.G.; Cerqueira, J.J.; Sousa, N.. "Differential impact of chronic stress along the hippocampal dorsal–ventral axis". Brain Structure and Function 220 2 (2015): 1205-1212. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944558041&partnerID=MN8TOARS. 10.1007/s00429-014-0713-0 Pinho, J.; Machado, C.; Oliveira, T.G.; Soares, I.; Magalhães, Z.; Maré, R.. "Dynamic myelopathy in Hirayama disease". Spine Journal 14 11 (2014): 2789-2790. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908547653&partnerID=MN8TOARS. 10.1016/j.spinee.2014.06.026 Mesquita, S.D.; Ferreira, A.C.; Falcao, A.M.; Sousa, J.C.; Oliveira, T.G.; Correia-Neves, M.; Sousa, N.; Marques, F.; Palha, J.A.. "Lipocalin 2 modulates the cellular response to amyloid beta". Cell Death and Differentiation 21 10 (2014): 1588-1599. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900894981&partnerID=MN8TOARS. 10.1038/cdd.2014.68 Chan, R.B.; Oliveira, T.G.; Cortes, E.P.; Honig, L.S.; Duff, K.E.; Small, S.A.; Wenk, M.R.; Shui, G.; Di Paolo, G.. "Comparative lipidomic analysis of mouse and human brain with Alzheimer disease". Journal of Biological Chemistry 287 4 (2012): 2678-2688. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856072382&partnerID=MN8TOARS. 10.1074/jbc.M111.274142 Roque, S.; Oliveira, T.G.; Nobrega, C.; Barreira-Silva, P.; Nunes-Alves, C.; Sousa, N.; Palha, J.A.; Correia-Neves, M.. "Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration". Frontiers in Behavioral Neuroscience FEBRUARY (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84855237730&partnerID=MN8TOARS. 10.3389/fnbeh.2011.00004 Oliveira, T.G.; Chan, R.B.; Tian, H.; Laredo, M.; Shui, G.; Staniszewski, A.; Zhang, H.; et al. "Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits". Journal of Neuroscience 30 49 (2010): 16419-16428. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650064098&partnerID=MN8TOARS. 10.1523/JNEUROSCI.3317-10.2010 Oliveira, T.G.; Di Paolo, G.. "Phospholipase D in brain function and Alzheimer's disease". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1801 8 (2010): 799-805. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953243856&partnerID=MN8TOARS. 10.1016/j.bbalip.2010.04.004 Longatto Filho, A.; Oliveira, T.G.; Pinheiro, C.; de Carvalho, M.B.; Curioni, O.A.; da Cunha Mercante, A.M.; Schmitt, F.C.; Gattás, G.J.F.. "How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?". World Journal of Surgical Oncology 5 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-39049171778&partnerID=MN8TOARS. 10.1186/1477-7819-5-140
Thesis / Dissertation	Oliveira, Tiago Gil. "The role of phospholipase D2 in Alzheimer's disease". PhD, 2010. http://hdl.handle.net/1822/12235.

Other

Other output

SorCS2 deletion leads to altered neuronal lysosome activity. 2021. Almeida, S.; Miranda, A.M.; Tóth, A.E.; Nielsen, M.S.; Oliveira, T.G.; Glerup, S.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85106370303&partnerID=MN8TOARS.
10.1101/2021.04.08.439000
Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. Cell Reports. 2019. Marinha, L.S.; Castanho, I.; Silva, R.R.; Bravo, F.V.; Miranda, A.M.; Xu, Y.; Point du Jour, K.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85112498654&partnerID=MN8TOARS.
10.2139/ssrn.3462748

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/11	The role of lipid signaling in Alzheimer’s disease	NeuroDay I3S Research Institute (Porto, Portugal)
2023/10	The role of lipid signaling in Alzheimer’s disease	1st Nova Medical School Research Week Nova Medical School (Lisboa, Portugal)
2023/10	Anti-amyloid antibody treatment for Alzheimer’s disease	46th European Society of Neuroradiology Annual Meeting ESNR (Vienna, Austria)
2023/09	The role of the phospholipase D pathway in hippocampal functioning and Alzheimer’s disease	2nd Symposium on lipids in brain diseases (Leiden, Netherlands)
2023/09	Lipidomic insights into Alzheimer’s disease pathogenesis	Lipidomic insights into Alzheimer’s disease pathogenesis FEBBS (Funchal, Portugal)
2023/06	Brain magnetic resonance imaging changes in Frontotemporal Dementia	37th Portuguese Meeting on Brain Aging and Dementia GEECD (Lisboa, Portugal)
2023/04	Lewy body co-pathology contributes to frontal lobe atrophy in Alzheimer’s disease and primary age-related tauopathy	4th Eurotau Meeting (Lille, France)
2022/12	The role of the phospholipase D pathway in hippocampal functioning and Alzheimer’s disease	Invited seminar Columbia University, Taub Institute (New York, United States)
2022/11	Unravelling Alzheimer’s disease pathogenesis through brain MRI & neuropathology approaches	Invited Seminar Champalimaud Foundation (Lisboa, Portugal)
2022/09	The role of the phospholipase D pathway in hippocampal functioning and Alzheimer’s disease	10th Westerberger Herbsttagung - Membranes and the Cytoskeleton in Health and Neurodegenerative Disease Osnabrück University (Osnabrück, Germany)
2022/04	The role of the phospholipase D pathway in the nervous system functioning and Alzheimer's disease	Invited Seminar University of Geneva (Geneva, Switzerland)
2022/02/03	Brain regional susceptibility to neurodegenerative disorders - from lipidomic signatures to MRI approaches (online)	Invited seminar Cornell University, NY, USA. Host: Mony de Leon (New York, United States)
2021/10/25	Primary age-related tauopathy (PART) and Alzheimer’s disease show differential magnetic resonance imaging atrophy patterns	3rd Eurotau Meeting Eurotau (Lille, France)
2021/10/15	The impact of chronic stress on the brain lipidome – implications for mood disorders and Alzheimer’s disease	XXI Portuguese Society for Biochemistry, National Congress of Biochemistry Portuguese Society for Biochemistry (Évora, Portugal)
2021/07/06	Differential impact of hippocampal longitudinal axis modulation in chronic stress and Alzheimer’s disease	Invited seminar NeuroSpin, Paris, France. Host: Sébastien Meriaux (Paris, France)
2021/02/14	Studying mood disorders and hippocampal functioning with lipidomic approaches	Sphingolipid Biology Webinar Series Sphingolipid Club - https://youtu.be/9IRpVXZ5co4 (Online Seminar, United States)
2020/12/15	Brain Imaging in Alzheimer’s disease – from clinical practice to research	International Workshop in Translational Neurology - Blood-Brain Barrier in the Clinical setting CNC, Coimbra, Portugal [Online Seminar] (Coimbra, Portugal)
2020/12/14	My path from Neuroscience to Neuroradiology	2020 Faculty of Medicine, University of Lisbon, Day of Research GAPIC, Office for Support for Scientific Research, Lisbon, Portugal (Lisboa, Portugal)
2020/12/14	14 years of the Minho MD/PhD Program	III Research Symposium of the Portuguese Medical Schools - Online Faculty of Medicine, University of Lisbon, Lisbon, Portugal (Lisboa, Portugal)
2020/09/04	Phospholipase D1 ablation disrupts mouse longitudinal hippocampal axis organization and functioning	American Society for Biochemistry and Molecular Biology – Lipid Research Division Seminar Series”. September - https://www.asbmb.org/meetings-events/phospholipases-and-disease [Online Seminar] American Society for Biochemistry and Molecular Biology – Lipid Research Division (Online Seminar, United States)
2020/09/01	Brain imaging in Alzheimer’s disease – emerging new concepts from imaging-pathology studies	34th Portuguese Dementia and Brain Aging Study Group Meeting. [Online Seminar] Portuguese Dementia and Brain Aging Study Group (Coimbra, Portugal)
2020/07/15	Lipid metabolism in hippocampal functioning	2nd Membrane Trafficking Workshop International Iberian Nanotechnology Institute, Braga, Portugal. [Online Seminar] (Braga, Portugal)
2020/01	Alzheimer's disease, dementia and neurodegeneration - from patients to basic research	Neuroscience and Mental Health course University of Coimbra (Coimbra, Portugal)
2019/10	Phospholipase D1 ablation disrupts dorsal-ventral hippocampal axis	2019 Society for Neuroscience Meeting Society for Neuroscience (Chicago, United States)
2019/10	The role of the phospholipase D pathway in the nervous system functioning and Alzheimer's disease	Invited Seminar Kyunghee Koh - Thomas Jefferson University (Philadelphia, Portugal)
2019/06	Differential lipid composition and regulation along the hippocampal longitudinal axis	1st Membrane Trafficking Workshop International Iberian Nanotechnology Institute (Braga, Portugal)
2019/06	The role of phospholipase D pathway in neurodegeneration	XVI Meeting of the Portuguese Society for Neuroscience Portuguese Society for Neuroscience (Lisboa, Portugal)
2019/03	Building an MD/PhD program as a scientific hub to promote biomedical research	Orpheus Conference – 2019 Orpheus - University College Dublin (Dublin, Ireland)
2018/11	Quantitative neuroimaging metrics to study neurodegenerative diseases	2018 Portuguese Neurology Society Conference Portuguese Neurology Society (Porto, Portugal)
2018/07	The role of phospholipase D in nervous system physiology and pathology	Invited seminar Mount Sinai Hospital - Edoardo M. Marcora (New York, United States)
2018/07	Lipids under stress	2nd Small Meeting on Endocytic Trafficking and Signaling International Iberian Nanotechnology Institute (Braga, Portugal)
2017/09	Lipids under stress – a lipidomic approach for the study of mood disorders	XII Sphingolipid Club Meeting Sphingolipid Club (Trabia, Italy)
2017/06	Macrostructural impact of Soccer in brain morphometry: MRI volumetric and cortical thickness analysis	XIII Portuguese Neuroradiology Meeting Portuguese Neuroradiology Society (Estarreja, Portugal)
2017/06	The impact of chronic stress on the rat brain lipidome”. Invited seminar	2017 – ICVS open day ICVS - University of Minho (Braga, Portugal)
2016/10	Lipids under stress – a lipidomic approach for the study of mood disorders	Invited seminar New York University - Robert C. Froemke (New York, United States)
2016/06	Lipids under stress – a lipidomic approach for the study of mood disorders	Invited seminar Ana Cristina Rego - University of Coimbra (Coimbra, Portugal)
2016/06	Lipids under stress – a lipidomic approach for the study of mood disorders	Invited seminar Friedrich-Alexander-University Erlangen-Nuremberg - Christian P. Müller (Erlangen, Germany)
2015/01	The role of antiphospholipid antibodies in the antiphospholipid syndrome	2015 Portuguese Stroke Conference Portuguese Stroke Society (Porto, Portugal)
2014/09	Lipid signaling in brain physiology and pathology	Thomas Jefferson / Minho Universities Joint Meeting - Invited seminar ICVS - University of Minho (Braga, Portugal)
2013/10	Lipid signaling in Alzheimer’s disease”. Invited seminar – “”,	IBRO Meeting – Current aspects in the pathophysiology of Alzheimer’s disease IBRO (Braga, Portugal)
2013/05	Characterization of a phospholipase D mutant C. elegans model	2013 European MD/PhD Conference European MD/PhD Association (Paris, France)
2010/11	The role of Phospholipase D2 in Alzheimer’s disease”. Selected from abstract submission	2010 Society for Neuroscience Meeting Society for Neuroscience (San Diego, United States)
2006/12	Tumour Lymphangiogenesis in Head and Neck Squamous Cell Carcinoma	XLI Congress of the Portuguese Society for Microscopy Portuguese Society for Microscopy (Braga, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2017 - Current	Lipid signaling determinants of hippocampal excitability Supervisor	Medicine (PhD)
2016 - Current	Anti-inflammatory effect of carbon monoxide on the neuron-microglia bidirectional communication Co-supervisor	Ageing and Chronic Diseases (PhD)
2015 - 2019	Dissecting the mechanisms of dynein recruitment to the nuclear envelope during neocortical development Co-supervisor	Medicina (PhD) Universidade do Minho, Portugal
2014 - 2019	Investigating the role of Taranis and Wingless/Wnt signaling in sleeping regulation Co-supervisor	Medicina (PhD) Universidade do Minho, Portugal
2014 - 2018	Endolysosomal dysfunction and exosome secretion: implications for neurodegenerative disorders Supervisor	Medicina (PhD) Universidade do Minho, Portugal
2013 - 2018	The role of signaling lipids in the nervous system physiology and pathology: mechanistic insights of the phospholipase D pathway in neurodegenerative diseases Supervisor	Envelhecimento e Doenças Crónicas (associação) (PhD) Universidade do Minho, Portugal
2014 - 2015	The impact of phospholipase D ablation in the mouse hippocampus Supervisor	Ciências da Saúde (Master) Universidade do Minho, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2014 - Current	ICVS International Seminar Series - Various (2014) Seminar (Co-organisor)	Universidade do Minho, Portugal
2018 - 2018	2nd MD/PhD retreat - As PhD in Medicine course director I organised the program retreat, which also had the participation of external committee member, Prof. Alcino Silva (UCLA, USA). (2018 - 2018) Meeting (President of the Organising Committee)	Universidade do Minho, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2023	Investigating the association of endocytic trafficking regulator CD2AP gene variant K633R and the risk of developing Alzheimer´s disease (Thesis) Main arguer	Farzaneh Sadat Mirfakhar (PhD) Universidade Nova de Lisboa, Portugal
2023	Corticostriatal circuitry dysfunction in neuropsychiatric disorders (Thesis) Arguer	Diana Rodrigues (PhD) Universidade do Minho, Portugal
2023	Psychostimulants and neuroninflammation: finding critical players in the crosstalk between glial cells and neurons (Thesis) Main arguer	Joana Catarina da Silva Bravo (PhD) Universidade do Porto, Portugal
2023	Self-modulation of executive system with real-time fMRI: a neurofeedback protocol design and implementation in autism (Thesis) Main arguer	Daniela Jardim Pereira (PhD) Universidade de Coimbra, Portugal
2023	Developmental venous anomalies, cerebral cavernous malformations and beyound: neuroimaging insight into pediatric cerebrovenous vascular malformations (Thesis) Main arguer	Ana Filipa Geraldo (PhD) Universidade do Porto, Portugal
2023	Dissecting the role of parvalbumin positive inhibitory neurons in the cellular and behavioral phenotypes associated with Gprasp2 deletion (Thesis) Main arguer	Mariana Barradas Serrano Laranjo (PhD) Universidade de Coimbra, Portugal
2023	The role of functional connectivity in the treatment of depression: exploring novel neuroimaging techniques Thesis Member	Joana Reis (PhD) Universidade do Minho, Portugal
2022/02/24	An integrative approach to the study of diet on cognitive function in ageing and effects of age on behavioural change: associations between Mediterranean diet and MRI-based measures and the effect of age on a brief motivational intervention (Thesis) Arguer	Belina Rodrigues (PhD) Universidade do Minho, Portugal
2022	The Role of Serotonin in Regulation of Benign Prostatic Growth – Implications for Benign Prostatic Hyperplasia Etiology (Thesis) Arguer	Emanuel Carvalho Dias (PhD)
2022	Apolipoprotein E lipidation in Alzheimer’s disease (Thesis) Main arguer	Karina Linder (PhD) Université de Genève, Switzerland
2022	MRI biomarkers of the stressed brain: disclosing interactions between perception, morphology and functioning (Thesis) Arguer	Inês Caetano (PhD) Universidade do Minho, Portugal
2022	Serotonergic signaling modulation as a thepareutic strategy for Machado-Joseph disease: finding the molecular traits (Thesis) Arguer	Stéphanie Oliveira (PhD) Universidade do Minho, Portugal
2022	Studying the neuroprotective role of bone marrow-derived mesenchymal stem cell secretome using in vitro and in vivo models of Parkinson’s disease (Thesis) Arguer	Bárbara Pinheiro (PhD) Universidade do Minho, Portugal
2021/12/16	The impact of the genetic risk factor BIN1 on Alzheimer’s disease development (Thesis) Main arguer	Catarina Perdigão (PhD) Universidade Nova de Lisboa, Portugal
2021/11/24	The human brain connectome in aging: MRI biomarkers of cognitive preservation and decline (Thesis) Arguer	Ana Coelho (PhD) Universidade do Minho, Portugal
2021/11/15	Carbon monoxide modulation of glial cells on cytoprotection (Thesis) Main arguer	Daniela Dias-Pedroso (PhD) Universidade Nova de Lisboa Comprehensive Health Research Centre, Portugal
2021/09/07	Chronic stress and glucocorticoid actions in brain plasticity and Tau pathology (Thesis) Arguer	Chrysoula Dioli (PhD) Universidade do Minho, Portugal
2021/07/07	Development of vascularizable hydrogels to promote spinal cord injury repair: from RGD to mimetic ligands (Thesis) Arguer	Luís António Rocha (PhD) Universidade do Minho, Portugal
2021/05/12	Insights from Caenorhabditis elegans models into neurogenetic disorders of the motor system: from fundamental to translational research (Thesis) Arguer	Jorge Diogo Da Silva (PhD) Universidade do Minho, Portugal
2021/05/04	Validation of a Novel Intervention Based on Digital Biofeedback for Home-based Rehabilitation after Hip or Knee Replacement (Thesis) Arguer	Fernando Correia (PhD) Universidade do Minho, Portugal
2021/02/04	Cognitive and emotional regulation in stress and obsessive-compulsive disorder (Thesis) Arguer	Sónia Ferreira (PhD) Universidade do Minho Escola de Medicina, Portugal
2020/11/01	Exploring the crosstalk between mood and metabolism: new insights from ageing, obesity and depression (Thesis) Arguer	Carlos Portugal Nunes (PhD) Universidade do Minho Escola de Medicina, Portugal
2020/09/04	The Role of TorsinA in Brain Lipid Metabolism (Thesis) Main arguer	Ana Cascalho (PhD) Katholieke Universiteit Leuven Departement Cellulaire en Moleculaire Geneeskunde, Belgium

Association member

	Society Organization name	Role
2023/05 - Current	Portuguese Society for Neuroscience	President
2017 - Current	Sphingolipid Club	Board Member
2019 - 2023	Portuguese Society for Neuroscience	Vice-President
2015 - 2019	Portuguese Society for Neuroscience	Secretary
2009 - 2010	Faculty 1000 biology	Faculty Member

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2018 - Current	Co-Responsible for the organization of the curricular area “Final Optional Project” – equivalent to the Master in Medicine thesis during the sixth year of Medical School	Final Optional Project	Universidade do Minho, Portugal
2018 - Current	Lecturer in “Clinical Neurosciences” – responsible for classes on clinical neuroimaging during the fourth year of Medical School	Clinical Neurosciences (Mestrado integrado)	Universidade do Minho, Portugal
2018 - Current	Lecturer in “Biopathology” - responsible for classes on various aspects of disease mechanisms during the third year of Medical School	Biopathology (Mestrado integrado)	Universidade do Minho, Portugal
2018 - Current	Lecturer in “Molecules and Cells” – responsible for classes on lipid signaling and metabolism during the first year of Medical School	Molecules and Cells (Mestrado integrado)	Universidade do Minho, Portugal
2017 - Current	Fundamentals in Neuroscience - Coordinator	Fundamentals in Neuroscience (Doutoramento)	Universidade do Minho, Portugal
2015 - Current	Responsible for the organization of the “Central Nervous System” course, as part of the second year Medical School curricular unit “Functional and Organic Systems III”	Functional and Organic Systems III (Mestrado integrado)	Universidade do Minho, Portugal
2011 - Current	Lecturer in Gross Anatomy, Neuroanatomy and Clinical Anatomy, as part of the academic training of the first and second year Medical School in “Functional and Organic Systems I, II and III”; and first year Medical School (4 year track) in “Fundamentals in Medicine”	Functional and Organic Systems I, II and III (Mestrado integrado)	Universidade do Minho, Portugal

Interview (tv / radio show)

	Program	Topic
2021/02/15 - 2021/02/15	RUM - Information Broadcast	Artificial Intelligence - Alzheimer's disease diagnosis

Distinctions

Award

2022	Prémio Pfizer Sociedade das Ciências Médicas de Lisboa, Portugal

Other distinction

2017	2017 Research Award (for the highest impact original research work in 2016)
2014	Scholarship in Clinical Research