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I graduated in 2003 and earned my PhD in Pharmaceutical Sciences from the University of Porto in 2007. I received my habilitation in Health Sciences from the University of Minho in 2024. Currently, I am a Principal Investigator with the Immunobiology of Inflammatory and Infectious Diseases Team at the Life and Health Sciences Research Institute, School of Medicine, University of Minho.
Identification

Personal identification

Full name
Ricardo Jorge Leal Silvestre

Citation names

  • Silvestre, Ricardo
  • Leal-Silvestre, RJ

Author identifiers

Ciência ID
FC10-05F4-581C
ORCID iD
0000-0002-9270-2717

Email addresses

  • ricardosilvestre@med.uminho.pt (Professional)

Telephones

Telephone
  • 253604811 (Professional)

Addresses

  • Microbiology and Infection Research Domain Life and Health Sciences Research Institute (ICVS): School of Medicine; University of Minho. Campos de Gualtar , 4710-057 , Braga, Braga, Portugal (Professional)

Websites

  • http://www.researchgate.net/profile/Ricardo_Silvestre (Professional)

Knowledge fields

  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
Spanish; Castilian Beginner (A1) Advanced (C1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2024/03/04
Concluded
 Agregação no ramo do conhecimento em Ciências da Saúde da Universidade do Minho. (Título de Agregado)
Universidade do Minho, Portugal
2007/12/13
Concluded
 PhD in Pharmaceutical Sciences in the discipline of Biochemistry (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
"Leishmania SIR2: Host cells interaction and vaccinal approach" (THESIS/DISSERTATION)
 Approved unanimously
2003/06/22
Concluded
 Ciências Farmacêuticas (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"_" (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2021/07/01 - Current Principal Investigator (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/07/01 - 2020/06/30 Auxiliary Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010/01/01 - 2014/06/30 Auxiliary Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008/01/01 - 2009/12/31 Postdoc (Research) Université Paris-Est Créteil Val de Marne Faculté de médecine, France
2003/10/01 - 2003/12/01 Research Trainee (Research) Institut de Recherche pour le Développement Délégation Régionale Occitanie, France
2003/01/01 - 2003/07/01 Research Trainee (Research) Institut Pasteur, France
2000/03/01 - 2002/10/01 Research Trainee (Research) Universidade do Porto Faculdade de Farmácia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/09/01 - 2021/06/30 Invited Assistant Professor (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/10/01 - 2014/06/30 Invited Assistant Professor (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Others

Category
Host institution 		Employer
2004/01/01 - 2007/12/01 PhD student Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2023/04/01 - Current Elucidating the role of apoptotic T cell death in Post-COVID-19 condition
APO-PCC
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 2CA-Braga
Ongoing
2021/03 - 2024/09 Elucidation of the Functional Roles of Lipid Metabolism During Canine Leishmaniasis
PTDC/CVT-CVT/4808/2020
DOI: 10.54499/2020.00185.CEECIND/CP1600/CT0004
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - 2021/06 Immunological basis of failure in controlling Mycobacterium tuberculosis infection.
PTDC/SAU-INF/28463/2017.
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/07 - 2021/06 Immunometabolic Networks in the Regulation of Visceral Leishmaniasis
Project INLEISH
Principal investigator
European Commission Seventh Framework Programme for Research and Technological Development
2019/06/01 - 2021/05/31 YoGut: a functional yogurt to prevent intestinal inflammation
Yogut
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Concluded
2019/04/01 - 2021/03/31 Feeding immunity: development of new nutraceuticals for visceral leishmaniasis
ESCMID Research Grant 2019
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 European Society of Clinical Microbiology and Infectious Diseases
Concluded
2018/04/01 - 2021/03/31 Immunometabolic networks for biomarker and therapy assessment in inflammatory disease
IMBIOM
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Concluded
2016/04 - 2020/03 New avenues for the development of personalized medical interventions for neurological, oncologic and surgical disorders
NORTE-45-2015-02
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Ongoing
2019/01 - 2019/12 Strategic Project Associate Laboratory, Life and Health Sciences Research Institute / Biomaterials, Biodegradables and Biomimetics Research Group (LA ICVS/3Bs 2019)
UID/Multi/50026/2019
Researcher
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/04 - 2018/05 Exploring the role of mesenchymal stem cells-mediated reprogramming of macrophages in rheumatoid arthritis.
MEMoRA
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Concluded
2012/05 - 2015/09 Cell communication by Leishmania microvesicles
grant.Provided by PTCRIS: 118644
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2011/04 - 2014/06 Development of a new immunological screening method for leishmaniasis using colloidal gold nanoparticles
grant.Provided by PTCRIS: 110732
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/09 Implication of sirtuin proteins in the regulation of antigen presenting cells apoptosis during leishmaniasis: a therapeutic approach
grant.Provided by PTCRIS: 100749
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/09 Role and mechanism of action of immunoregulatory iNKT and DC cells in Leishmania infection: new approaches for vaccination?
grant.Provided by PTCRIS: 101017
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2009/02 - 2013/01 Le rôle des sirtuins dans la modulation de la mort des cellules présentatrices de l'antigène au cours de la leishmaniose viscérale
LEISH-APO
Researcher
Institut Mondor de recherche biomédicale, France
 Agence nationale de la recherche
Concluded
2007/11 - 2010/12 The Leishmania TDR1 family-related gene: functional studies and evaluation of TDR1 recombinant protein and knockout vaccines against leishmaniasis.
grant.Provided by PTCRIS: 65047
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2007/08 - 2009/12 ROLE OF DENDRITIC CELLS IN LEISHMANIASIS: intracellular signalling pathways activated by virulent and attenuated parasite Leismania infantum
grant.Provided by PTCRIS: 67351
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2007/01 - 2009/02 ANTI-LEISHMANIAL DRUGS: study the role of novel polyamine derivative compounds for drug therapy and search for target specific SIR2 inhibitors
grant.Provided by PTCRIS: 82728
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2005/07 - 2008/06 The Leishmania SIR2 family-related gene: functional studies and evaluation of SIR2 recombinant DNA and knockout vaccine to protect against Leishmnaniasis
grant.Provided by PTCRIS: 59840
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2005/07 - 2007/08 ANTI-LEISHMANIAL DRUGS: study the role of novel polyamine derivative compounds for drug therapy and search for target specific SIR2 inhibitors
grant.Provided by PTCRIS: 59837
Researcher
Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2023/01/01 - 2026/01/01 Safety profile and therapeutic potential of psilocybin and other Psilocybe mushrooms¿ phytochemicals for the treatment of depression: A preclinical study
2022.02020.PTDC
Instituto Universitário de Ciências da Saúde, Portugal
 Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT
2023/03/01 - 2024/08/31 Immunometabolic requirements in Buruli Ulcer
10.54499/2022.05266.PTDC
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2024/06/30 Sporob_SiA: Elucidation of the role of sialidase 1 in the severity of feline sporotrichosis caused by Sporothrix brasiliensis
2022.03348.PTDC
10.54499/2022.03348.PTDC
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 O sistema simpático periférico como alvo de imunomodulação na patofisiologia da lesão vertebro-medular
EXPL/MED-PAT/0931/2021
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/15 - 2021/07/14 Bases imunológicas da suscetibilidade às infeções por Mycobacterium tuberculosis
PTDC/SAU-INF/28463/2017
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2015/07/01 - 2020/06/30 Subversion of the host cell energy metabolism by intracellular pathogens: implications on immunity and innovative immunotherapeutic approaches
IF/00021/2014
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2011/04/01 - 2014/06/30 Desenvolvimento de um novo método imunológico para o rastreio da leishmaniose canina utilizando nanoparticulas de ouro coloidal
PTDC/CVT/110732/2009
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Ciência Animal e Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Implicação das proteínas sirtuin na regulação da apoptose de células apresentadoras de antigenio durante a leishmaniose: uma abordagem terapêutica
PTDC/SAU-FCF/100749/2008
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Papel e mecanismo de acção das células imunorreguladoras iNKT e DC na infecção por Leishmania: novas abordagens de vacinação?
PTDC/SAU-FCF/101017/2008
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/11/01 - 2010/12/31 Estudos funcionais da família de genes relacionados com a TDR1 e análise da proteína recombinante e do “knockout” da TDR1 como vacinas contra a leishmaniose.
PTDC/CVT/65047/2006
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/08/16 - 2009/12/31 PAPEL DAS CÉLULAS DENDRITICAS NA LEISHMANIOSE: estudos de sinalização intracelular na infecção pelo parasita Leismania infantum virulento ou atenuado.
PTDC/SAU-FCF/67351/2006
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/07/01 - 2008/06/30 Família de genes relacionados com SIR2 de Leishmania: Estudos funcionais e análise das vacinas de DNA recombinante da SIR2 e de “knockout” para proteger contra a Leishmaniose
POCI/CVT/59840/2004
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/07/01 - 2007/08/31 DROGAS ANTI-LEISHMANIA: estudo do papel de novas drogas derivados poliaminicos com fim terapêutico e procura de alvos específicos para inibidores da SIR2
POCI/SAU-FCF/59837/2004
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Silvestre, Ricardo. Metabolic Interaction in Infection. Springer International Publishing. 2018.
    Published • 10.1007/978-3-319-74932-7
Book chapter
  1. Moreira D; Estaquier J; Cordeiro-da-Silva A; Silvestre R; Moreira, Diana; Estaquier, Jérôme; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Evaluating the Role of Host AMPK in Leishmania Burden.". In Methods in molecular biology (Clifton, N.J.), 551-563. Springer New York, 2018.
    10.1007/978-1-4939-7598-3_35
  2. Silvestre, Ricardo. "O Sistema Imunológico como alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental, 201-218. 2018.
  3. Mesquita I; Vergnes B; Silvestre R. "Alterations on Cellular Redox States upon Infection and Implications for Host Cell Homeostasis.". In Experientia supplementum (2012), 197. Springer International Publishing, 2018.
    Published • 10.1007/978-3-319-74932-7_4
  4. Moreira D; Estaquier J; Cordeiro-da-Silva A; Silvestre R. "Metabolic Crosstalk Between Host and Parasitic Pathogens.". In Experientia supplementum (2012), 421-458. Springer International Publishing, 2018.
    Published • 10.1007/978-3-319-74932-7_12
  5. Silvestre, Ricardo; Mesquita, I.; Moreira, D.; Sampaio-Marques, B.; Laforge, M.; Cordeiro-da-Silva, A.; Ludovico, P.; Estaquier, J.; Silvestre, R.. "AMPK in Pathogens". In AMP-activated Protein Kinase, Experientia Supplementum, 287-323. 2016.
    Published
  6. Silvestre, Ricardo. "Imunologia da Infecção". In Fundamentos de Imunologia, 427-454. 2012.
    Published
Conference abstract
  1. Maria B. André; Silvestre, Ricardo; Azevedo, Rui M.S.; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Profiling of rat mRNA transcripts degradation for the postmortem interval estimation". Paper presented in I Congresso Internacional da TOXRUN / V Congresso Internacional da Associação Portuguesa de Ciências Forenses / XIV Jornadas Científicas do Departamento de Ciências do Instituto Universitário de Ciências da Saúde, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.249
  2. Neves, Bruno; Silvestre, Ricardo; Cunha, Joana; Tavares, Joana; Resende, Mariana; Ouaissi, Ali; Lopes, MC; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains". Paper presented in 2nd European Congress of Immunology, Berlim, 2009.
    Published
  3. Tavares, Joana; Araújo, Natália; Silvestre, Ricardo; Borges, Margarida; Ouaissi, M; Cordeiro-da-Silva, Anabela. "Antibodies against rLmS3arp enhance the Leishmania uptake by murine peitoneal macrophages". Paper presented in XXIX Reunião Anual da Sociedade Portuguesa de Imunologia, Porto, 2003.
    Published
Conference paper
  1. Carvalho, Marina; Conceição, Andreia; Justino, Mónica; Silvestre, Ricardo; Pacheco, Sara; Pacheco, Susana; Mendes, Sónia. "Identification os Schematic Facial Expressions in Children and Adolescents: Gender Differences and Age Effects". Paper presented in 14th European Conference on Facial Expression, Coimbra, 2012.
    Published
Conference poster
  1. Gonçales, RA; Marcela Oliveira; Ana Baptista; Fernando Rodrigues; Torrado, Egídio; Sandra Costa; Silvestre, Ricardo; et al. "Itaconate controls granulomatous inflammation in sarcoidosis". Paper presented in XLVIII SPI Annual Meeting, 2023.
  2. Almeida-Nunes, DL; Nunes, Mariana; Osorio, Hugo; Ferreira, Verónica; Lobo, Claudia; Monteiro, Paula; Henriques Abreu, Miguel; et al. "Análise proteómica de ascites de pacientes com cancro do ovário reflete a modificação metabólica no microambiente tumoral durante a quimioterapia". Paper presented in 8º Curso Avançado de Ginecologia Oncológica, realized in Instituto Português de Oncologia do Porto, Francisco Gentil, EPE, Porto, Portugal, 2023.
  3. Almeida-Nunes, Diana Luísa; Mendes-Frias, Ana ; Dinis-Oliveira, Ricardo Jorge; Silvestre, Ricardo; Ricardo, Sara. "The influence of tumor microenvironment immunein ovarian cancer ascites". Paper presented in The Structural Microenvironment: Breaking down the walls of cancer, 2023.
  4. Mendes-Frias, Ana ; Araújo, Marta; Silvestre, Ricardo. "Characterization of Leishmania donovani infection in the gut: from the epithelial barrier to the immune system". Paper presented in Leishmaniasis 2022, 2022.
  5. Almeida-Nunes, Diana Lua; Mendes-Frias, Ana ; Dinis-Oliveira, Ricardo Jge; Silvestre, Ricardo; Ricardo, Sara. "Immune tumor microenvironment of ovarian cancer ascites". 2022.
  6. Mendes-Frias, Ana ; Gaifem, Joana; Lopes, Luís; Silvestre, Ricardo. "Unraveling the dinamic effect of Branched Chain Amino Acids in the gut". Paper presented in Annual Meeting of Portuguese Society of Immunology (online), 2021.
  7. Antunes, Daniela; Rodrigues, Cláudia S.; Gonçalves, Samuel M.; Duarte-Oliveira, Cláudio; Campos, Cláudia F.; Rodrigues, Fernando; Silvestre, Ricardo; Cunha, Cristina; Carvalho, Agostinho. "Glutamine metabolism regulates the immune response to the fungal pathogen Aspergillus fumigatus". Paper presented in XLV SPI Annual Meeting, 2019.
  8. Gaifem, Joana; Gonçalves, L.G; Dinis-Oliveira, R.J.; Cunha, C.; Carvalho, A.; Torrado, E.; Rodrigues, F.; et al. "L- Threonine supplementation during colitis onset delays disease". Paper presented in XLIV Annual Meeting of the Portuguese Society for Immunology, 2018.
  9. Gaifem, Joana; Garzón, MJ; Ubeda, C; Gonçalves, LG; Longatto-Filho, A; Belinha, A; Mesquita, I; et al. "Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis.". Paper presented in TOLL 2018, Editing Innate Immunity., 2018.
  10. Gonçalves, Samuel M.; Rodrigues, Cláudia S.; Campos, Cláudia F.; Duarte-Oliveira, Cláudio; Gaifem, Joana; van de Veerdonk, Frank L.; Campos Jr., António; et al. "Genetically-determined NLRP3 hyperactivation confers risk to fungal disease by compromising macrophage function". Paper presented in XLIII SPI Annual Meeting, 2018.
  11. Duarte-Oliveira, Cláudio; Campos, Cláudia F.; Rodrigues, Cláudia S.; Gonçalves, Samuel M.; Gaifem, Joana; Mesquita, Inês; Garlanda, Cecilia; et al. "Pentraxin-3 promotes IL-10-dependent immune protection to the oppurtunistic fungus Trichosporon asahii". Paper presented in XLIII SPI Annual Meeting, 2018.
  12. Gonçalves, Samuel M.; Lagrou, Katrien; Rodrigues, Cláudia S.; Campos, Cláudia F.; Bernal-Martínez, Leticia; Rodrigues, Fernando; Silvestre, Ricardo; et al. "Evaluation of alveolar cytokines as biomarkers for invasive pulmonary aspergillosis in high-risk patients". Paper presented in 8th Advances Against Aspergillosis, 2018.
  13. Duarte-Oliveira, Cláudio; Campos, Cláudia F.; Rodrigues, Cláudia S.; Gonçalves, Samuel M.; Gaifem, Joana; Barbosa, Ana M.; Ferreira, Catarina R.; et al. "IL-10 overexpression in vivo promotes susceptibility to aspergillosis by supressing innate and adaptive pulmonary antifungal immunity". Paper presented in 8th Advances Against Aspergillosis, 2018.
  14. Correia, Clara R.; Gaifem, Joana; Oliveira, Mariana B.; Silvestre, Ricardo; Mano, João F.. "Influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages". Paper presented in Tissue Engineering and Regenerative Medicine International Society - European Chapter Meeting (TERMIS-EU), 2017.
  15. Gaifem, Joana; Araújo, Andreia; Belinha, Ana; Mesquita, Inês; Gonçalves, Luís; Santos, Sophia; Torrado, Egídio; et al. "Immunometabolic characterization of the intestinal mucosa upon chemically-induced colitis in mice from different animal facilities". Paper presented in Summer Frontiers 2016 – Systems Biology of Innate Immunity, 2016.
  16. Castro, Flávia; Cardoso, Vânia; Silvestre, Ricardo; Pedrosa, Jorge; Saraiva, Margarida; Castro, António G.; Torrado, Egídio. "IL-10 mediates susceptibility to Listeria monocytogenes infection by modulating the accumulation and differentiation of CD11b+ Ly6C+ monocytes". Paper presented in XL Annual Meeting of the Portuguese Society of Immunology (SPI) | Lisboa, Portugal, 2014.
  17. Carvalho, Marina; Conceição, Andreia; Andrade, Carla; Justino, Mónica; Silvestre, Ricardo; Pacheco, Sara; Borralha, Sergio; et al. "Trajectórias Desenvolvimentais dos Problemas Emocionais e Comportamentais na Infância e Adolescência". Paper presented in VIII Simpósio Nacional de Investigação em Psicologia, 2013.
  18. Carvalho, Marina; Conceição, Andreia; Justino, Mónica; Silvestre, Ricardo; Pacheco, Sara; Pacheco, Susana; Mendes, Sónia. "Factores Individuais e Familiares Relacionados com os Problemas de Comportamento em Jovens". Paper presented in 2º Seminário de Intervenção Psicológica com Crianças e Adolescentes: Intervenções Empiricamente Validadas, 2012.
  19. Santarém, Nuno; Cunha, Joana; Silva, Carla; Moreira, Diana; Silvestre, Ricardo; Cordeiro-da-Silva, Anabela. "Poster 14 The development of a semi-defined medium for growth of Leishmania infantum". Paper presented in 3rd I3S Scientific Retreat, 2012.
  20. Resende, Mariana; Moreira, Diana; Cunha, Joana; Augusto, J; Neves, Bruno; Cruz, Maria Teresa; Estaquier, Jerôme; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Leishmania-infected mature dendritic cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype". Paper presented in 3rd I3S Scientific Retreat, 2012.
  21. Resende, Mariana; Cunha, Joana; Costa-Lima, Sofia; Moreira, Diana; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Poster 23 Early stages of visceral Leishmania infection". Paper presented in 2nd I3S Scientific Retreat, 2011.
  22. Robalo, Ana Luísa; Pereira, JA; Resende, Mariana; Moreira, Diana; Cunha, Joana; Costa-Lima, Sofia; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Activation of IL-27 p28 gene transcription on antigen presenting cells infected with Leishmania infantum". Paper presented in XXXVII Annual Meeting of the Portuguese Society for Immunology, 2011.
  23. Resende, Mariana; Moreira, Diana; Cunha, Joana; Neves, Bruno; Costa-Lima, Sofia; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Infected but not Bystander Dendritic Cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype". Paper presented in XXXVII Annual Meeting of the Portuguese Society for Immunology, 2011.
  24. Resende, Mariana; Silvestre, Ricardo; Neves, Bruno; Cunha, Joana; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Differential effect of Leishmania infantum on infected and bystander dendritic cells". Paper presented in XXXVI Annual Meeting of the Portuguese Society for Immunology, 2010.
  25. Silvestre, Ricardo; Santarém, Nuno; Cunha, Joana; Cardoso, Luís; Nieto, Javier; Carrillo, Eugenia; Moreno, Javier; Cordeiro-da-Silva, Anabela. "Poster 530 Serological evaluation of experimentally infected dogs by LicTXNPx–ELISA and amastigote-flow cytometry". Paper presented in 4th Worldleish Congress on Leishmaniasis, 2009.
  26. Silvestre, Ricardo; Santarém, Nuno; Moreira-Teixeira, Lúcia; Cunha, Joana; Schalling, HD; Cordeiro-da-Silva, Anabela. "Poster 526 Evaluation of Leishmania species reactivity in the Human serological diagnostic of leishmaniasis". Paper presented in 4th Worldleish Congress on Leishmaniasis, 2009.
  27. Neves, Bruno; Silvestre, Ricardo; Cunha, Joana; Tavares, Joana; Resende, Mariana; Ouaissi, Ali; Lopes, MC; Cruz, Maria Teresa; Cordeiro-da-Silva, Anabela. "Poster PA11/60 Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains". Paper presented in European Congress of Immunology 2009, 2009.
Journal article
  1. Gaifem, Joana; Mendes-Frias, Ana ; Wolter, Mathis; Steimle, Alex; Garzón, Maria Jose; Ubeda, Carles; Nobre, Clarisse; et al. "Akkermansia muciniphila and Parabacteroides distasonis synergistically protect from colitis by promoting ILC3 in the gut". mBio 15 4 (2024): http://dx.doi.org/10.1128/mbio.00078-24.
    10.1128/mbio.00078-24
  2. Afonso, Julieta; Catarina Barbosa-Matos; Silvestre, Ricardo; Pereira-Vieira, Joana; Gonçalves, Samuel Martins; Mendes-Alves, Camille; Parpot, Pier; et al. "Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect". Cancers 16 7 (2024): 1418. http://dx.doi.org/10.3390/cancers16071418.
    Published • 10.3390/cancers16071418
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  69. Moreira, D.; Rodrigues, V.; Abengozar, M.; Rivas, L.; Rial, E.; Laforge, M.; Li, X.; et al. "Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis". PLoS Pathogens 11 3 (2015): 1-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926480675&partnerID=MN8TOARS.
    10.1371/journal.ppat.1004684
  70. Garcia, J.; Costa, V.M.; Carvalho, A.T.P.; Silvestre, R.; Duarte, J.A.; Dourado, D.F.A.R.; Arbo, M.D.; et al. "A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B". Archives of Toxicology 89 12 (2015): 2305-2323. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949323314&partnerID=MN8TOARS.
    10.1007/s00204-015-1582-x
  71. Ana Oliveira; Ricardo J. Dinis-Oliveira; Augusto Nogueira; Ferraz Gonçalves; Paula Silva; Cláudia Vieira; Ricardo Silvestre; Félix Carvalho; Rui Medeiros. "Interleukin-1ß genotype and circulating levels in cancer patients: Metastatic status and pain perception". Clinical Biochemistry (2014): http://dx.doi.org/10.1016/j.clinbiochem.2014.04.009.
    10.1016/j.clinbiochem.2014.04.009
  72. Vasco Rodrigues; Anabela Cordeiro-da-Silva; Mireille Laforge; Ali Ouaissi; Khadija Akharid; Ricardo Silvestre; Jérôme Estaquier. "Impairment of T Cell Function in Parasitic Infections". PLoS Negl Trop Dis 8 2 (2014): e2567-e2567. http://dx.doi.org/10.1371/journal.pntd.0002567.
    10.1371/journal.pntd.0002567
  73. Sofia A. Costa Lima; Ricardo Silvestre; Daniela Barros; Joana Cunha; Maria Teresa Baltazar; Ricardo Jorge Dinis-Oliveira; Anabela Cordeiro-da-Silva. "Crucial CD8+ T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis". Nanomedicine: Nanotechnology, Biology and Medicine (2014): http://dx.doi.org/10.1016/j.nano.2013.12.013.
    10.1016/j.nano.2013.12.013
  74. Rodrigues, V.; Laforge, M.; Campillo-Gimenez, L.; Soundaramourty, C.; Correia-de-Oliveira, A.; Dinis-Oliveira, R.J.; Ouaissi, A.; et al. "Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques". PLoS Pathogens 10 4 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84901321731&partnerID=MN8TOARS.
    10.1371/journal.ppat.1004096
  75. Santarém, N.; Cunha, J.; Silvestre, R.; Silva, C.; Moreira, D.; Ouellette, M.; Cordeiro-Da-Silva, A.. "The impact of distinct culture media in Leishmania infantum biology and infectivity". Parasitology 141 2 (2014): 192-205. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893953449&partnerID=MN8TOARS.
    10.1017/S0031182013001388
  76. Sousa, S.; Cardoso, L.; Reed, S.G.; Reis, A.B.; Martins-Filho, O.A.; Silvestre, R.; Cordeiro da Silva, A.. "Development of a Fluorescent Based Immunosensor for the Serodiagnosis of Canine Leishmaniasis Combining Immunomagnetic Separation and Flow Cytometry". PLoS Neglected Tropical Diseases 7 8 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84883345914&partnerID=MN8TOARS.
    10.1371/journal.pntd.0002371
  77. Laforge, M.; Limou, S.; Harper, F.; Casartelli, N.; Rodrigues, V.; Silvestre, R.; Haloui, H.; et al. "DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV". PLoS Pathogens 9 5 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84878487502&partnerID=MN8TOARS.
    10.1371/journal.ppat.1003328
  78. Santarém, N.; Racine, G.; Silvestre, R.; Cordeiro-da-Silva, A.; Ouellette, M.. "Exoproteome dynamics in Leishmania infantum". Journal of Proteomics 84 (2013): 106-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877062495&partnerID=MN8TOARS.
    10.1016/j.jprot.2013.03.012
  79. Resende, M.; Moreira, D.; Augusto, J.; Cunha, J.; Neves, B.; Cruz, M.T.; Estaquier, J.; Cordeiro-da-Silva, A.; Silvestre, R.. "Leishmania-infected MHC class IIhigh dendritic cells polarize CD4+ T cells toward a nonprotective T-bet+ IFN-¿+ IL-10+ phenotype". Journal of Immunology 191 1 (2013): 262-273. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879675210&partnerID=MN8TOARS.
    10.4049/jimmunol.1203518
  80. Lopes, A.P.; Sousa, S.; Dubey, J.; Ribeiro, A.J.; Silvestre, R.; Cotovio, M.; Schallig, H.D.F.H.; Cardoso, L.; Cordeiro-Da-Silva, A.. "Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal". Parasites and Vectors 6 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879033849&partnerID=MN8TOARS.
    10.1186/1756-3305-6-178
  81. Sampaio-Silva, F.; Magalhães, T.; Carvalho, F.; Dinis-Oliveira, R.J.; Silvestre, R.. "Profiling of RNA Degradation for Estimation of Post Morterm Interval". PLoS ONE 8 2 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84874242041&partnerID=MN8TOARS.
    10.1371/journal.pone.0056507
  82. Sampaio-Silva, F.; Magalhães, T.; Carvalho, F.; Dinis-Oliveira, R.J.; Silvestre, R.. "Correction: Profiling of RNA degradation for estimation of post mortem interval (PLoS ONE) 8, 2 (e56507) DOI: 10.1371/journal.pone.0056507". PLoS ONE 8 6 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896119826&partnerID=MN8TOARS.
    10.1371/annotation/cb8b37ac-cbe2-45e3-b9fe-d62e7ced4b25
  83. Jérôme Estaquier; Vasco Rodrigues; Ricardo Silvestre; Romain Estaquier; Bernard Krust; Mireille Laforge. "Apoptose et Sida, une affaire d’intégration ?". Med Sci (Paris) 29 12 (2013): 1094â¿¿1096-1094â¿¿1096. http://dx.doi.org/10.1051/medsci/20132912011.
    10.1051/medsci/20132912011
  84. Oliveira, Ana; Sampaio-Silva, Fernanda; Carvalho, Felix; Silvestre, Ricardo; Dinis-Oliveira, Ricardo Jorge. "Development of a simple and rapid spectrophotometric method for the quantification of carboxyhemoglobin". Toxicology Letters 221 (2013): S186-S186. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323865800572&KeyUID=WOS:000323865800572.
    10.1016/j.toxlet.2013.05.422
  85. Moreira, Diana; Santarém, Nuno; Loureiro, Inês; Tavares, Joana; Silva, Ana Marta; Amorim, Ana Marina; Ouaissi, Ali; Cordeiro-da-Silva, Anabela; Silvestre, Ricardo. "Impact of Continuous Axenic Cultivation in Leishmania infantum Virulence". PLoS Neglected Tropical Diseases 6 1 (2012): e1469. http://dx.doi.org/10.1371/journal.pntd.0001469.
    10.1371/journal.pntd.0001469
  86. Costa Lima, S.A.; Resende, M.; Silvestre, R.; Tavares, J.; Ouaissi, A.; Lin, P.K.T.; Cordeiro-Da-Silva, A.. "Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: In vitro and in vivo studies". Nanomedicine 7 12 (2012): 1839-1849. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871263911&partnerID=MN8TOARS.
    10.2217/nnm.12.74
  87. Silva, A.M.; Tavares, J.; Silvestre, R.; Ouaissi, A.; Coombs, G.H.; Cordeiro-da-Silva, A.. "Characterization of Leishmania infantum thiol-dependent reductase 1 and evaluation of its potential to induce immune protection". Parasite Immunology 34 6 (2012): 345-350. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860914599&partnerID=MN8TOARS.
    10.1111/j.1365-3024.2012.01361.x
  88. Ribeiro, R.; Monteiro, C.; Silvestre, R.; Castela, A.; Coutinho, H.; Fraga, A.; Príncipe, P.; et al. "Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma". Experimental Biology and Medicine 237 10 (2012): 1155-1162. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868224535&partnerID=MN8TOARS.
    10.1258/ebm.2012.012131
  89. Garibal, J.; Laforge, M.; Silvestre, R.; Mouhamad, S.; Campillo-Gimenez, L.; Lévy, Y.; Estaquier, J.. "IL-2 immunotherapy in chronically SIV-infected Rhesus Macaques". Virology Journal 9 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84869497228&partnerID=MN8TOARS.
    10.1186/1743-422X-9-220
  90. Rodrigues, V.; Cordeiro-da-Silva, A.; Laforge, M.; Ouaissi, A.; Silvestre, R.; Estaquier, J.. "Modulation of mammalian apoptotic pathways by intracellular protozoan parasites". Cellular Microbiology 14 3 (2012): 325-333. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857441470&partnerID=MN8TOARS.
    10.1111/j.1462-5822.2011.01737.x
  91. Sousa, S.; Lopes, A.P.; Cardoso, L.; Silvestre, R.; Schallig, H.; Reed, S.G.; Cordeiro da Silva, A.. "Seroepidemiological survey of Leishmania infantum infection in dogs from northeastern Portugal". Acta Tropica 120 1-2 (2011): 82-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052088790&partnerID=MN8TOARS.
    10.1016/j.actatropica.2011.06.003
  92. Gazanion, E.; Garcia, D.; Silvestre, R.; Gérard, C.; Guichou, J.F.; Labesse, G.; Seveno, M.; et al. "The Leishmania nicotinamidase is essential for NAD + production and parasite proliferation". Molecular Microbiology 82 1 (2011): 21-38. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053232281&partnerID=MN8TOARS.
    10.1111/j.1365-2958.2011.07799.x
  93. Neves, B.M.; Silvestre, R.; Resende, M.; Ouaissi, A.; Cunha, J.; Tavares, J.; Loureiro, I.; et al. "Activation of phosphatidylinositol 3-kinase/akt and impairment of nuclear factor-kB: Molecular mechanisms behind the arrested maturation/activation state of leishmania infantum-infected dendritic cells". American Journal of Pathology 177 6 (2010): 2898-2911. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650195216&partnerID=MN8TOARS.
    10.2353/ajpath.2010.100367
  94. Santarém, N.; Silvestre, R.; Cardoso, L.; Schallig, H.; Reed, S.G.; Cordeiro-da-Silva, A.. "Application of an improved enzyme-linked immunosorbent assay method for serological diagnosis of canine leishmaniasis". Journal of Clinical Microbiology 48 5 (2010): 1866-1874. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951783796&partnerID=MN8TOARS.
    10.1128/JCM.02402-09
  95. Silvestre, Ricardo; Silva, Ana M.; Cordeiro-da-Silva, Anabela; Ouaissi, Ali. "The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein". Immunology 128 4 (2009): 484-499. http://dx.doi.org/10.1111/j.1365-2567.2009.03132.x.
    10.1111/j.1365-2567.2009.03132.x
  96. Neves, Bruno Miguel; Cruz, Maria Teresa; Francisco, Vera; Garcia-Rodriguez, Cármen; Silvestre, Ricardo; Cordeiro-da-Silva, Anabela; Dinis, Augusto M.; et al. "Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell Th1/Th2 cytokine/chemokine polarizing profile". Molecular Immunology 46 13 (2009): 2481-2492. http://dx.doi.org/10.1016/j.molimm.2009.05.021.
    10.1016/j.molimm.2009.05.021
  97. Silvestre, R.; Santarém, N.; Tavares, J.; Silva, A.M.; Cordeiro-da-Silva, A.. "Recognition of Leishmania parasites by innate immunity". Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry 9 2 (2009): 106-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350001577&partnerID=MN8TOARS.
    10.2174/187152209789000713
  98. Silvestre, R.; Santarém, N.; Teixeira, L.; Cunha, J.; Schallig, H.; Cordeiro-da-Silva, A.. "Evaluation of Leishmania species reactivity in human serologic diagnosis of leishmaniasis". American Journal of Tropical Medicine and Hygiene 81 2 (2009): 202-208. http://www.scopus.com/inward/record.url?eid=2-s2.0-68549109500&partnerID=MN8TOARS.
  99. Silvestre, Ricardo; Santarém, Nuno; Cunha, Joana; Cardoso, Luís; Nieto, Javier; Carrillo, Eugenia; Moreno, Javier; Cordeiro-da-Silva, Anabela. "Serological evaluation of experimentally infected dogs by LicTXNPx–ELISA and amastigote-flow cytometry". Veterinary Parasitology 158 1-2 (2008): 23-30. http://dx.doi.org/10.1016/j.vetpar.2008.09.001.
    10.1016/j.vetpar.2008.09.001
  100. Silvestre, Ricardo; Cordeiro-da-Silva, Anabela; Ouaissi, Ali. "Live attenuated Leishmania vaccines: a potential strategic alternative". Archivum Immunologiae et Therapiae Experimentalis 56 2 (2008): 123-126. http://dx.doi.org/10.1007/s00005-008-0010-9.
    10.1007/s00005-008-0010-9
  101. Ouaïssi, M.; Sielezneff, I.; Silvestre, R.; Sastre, B.; Bernard, J.-P.; Lafontaine, J.S.; Payan, M.J.; et al. "High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas". Annals of Surgical Oncology 15 8 (2008): 2318-2328. http://www.scopus.com/inward/record.url?eid=2-s2.0-48149115853&partnerID=MN8TOARS.
    10.1245/s10434-008-9940-z
  102. Silvestre, R.; Santarém, N.; Cunha, J.; Cardoso, L.; Nieto, J.; Carrillo, E.; Moreno, J.; Cordeiro-da-Silva, A.. "Serological evaluation of experimentally infected dogs by LicTXNPx-ELISA and amastigote-flow cytometry". Veterinary Parasitology 158 1-2 (2008): 23-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-53549110220&partnerID=MN8TOARS.
    10.1016/j.vetpar.2008.09.001
  103. Menezes Cabral, S.; Leal Silvestre, R.; Moreira Santarém, N.; Costa Tavares, J.; Franco Silva, A.; Cordeiro-da-Silva, A.. "A Leishmania infantum cytosolic tryparedoxin activates B cells to secrete interleukin-10 and specific immunoglobulin". Immunology 123 4 (2008): 555-565. http://www.scopus.com/inward/record.url?eid=2-s2.0-39549123620&partnerID=MN8TOARS.
    10.1111/j.1365-2567.2007.02725.x
  104. Silvestre, R.; Cordeiro-Da-Silva, A.; Santarém, N.; Vergnes, B.; Sereno, D.; Ouaissi, A.. "SIR2-deficient Leishmania infantum induces a defined IFN-¿/IL-10 pattern that correlates with protection". Journal of Immunology 179 5 (2007): 3161-3170. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547871761&partnerID=MN8TOARS.
  105. Santarém, N.; Silvestre, R.; Tavares, J.; Silva, M.; Cabral, S.; Maciel, J.; Cordeiro-Da-Silva, A.. "Immune response regulation by Leishmania secreted and nonsecreted antigens". Journal of Biomedicine and Biotechnology 2007 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-34447542289&partnerID=MN8TOARS.
    10.1155/2007/85154
  106. Silvestre, R.; Cordeiro-Da-Silva, A.; Tavares, J.; Sereno, D.; Ouaissi, A.. "Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies". Immunology 119 4 (2006): 529-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750853289&partnerID=MN8TOARS.
    10.1111/j.1365-2567.2006.02468.x
  107. Sereno, D.; Monte Alegre, A.; Silvestre, R.; Vergnes, B.; Ouaissi, A.. "In vitro antileishmanial activity of nicotinamide". Antimicrobial Agents and Chemotherapy 49 2 (2005): 808-812. http://www.scopus.com/inward/record.url?eid=2-s2.0-12944275536&partnerID=MN8TOARS.
    10.1128/AAC.49.2.808-812.2005
  108. Freitas Jr., L.H.; Hernandez-Rivas, R.; Ralph, S.A.; Montiel-Condado, D.; Ruvalcaba-Salazar, O.K.; Rojas-Meza, A.P.; Mâncio-Silva, L.; et al. "Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites". Cell 121 1 (2005): 25-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-20144389331&partnerID=MN8TOARS.
    10.1016/j.cell.2005.01.037
Newspaper article
  1. Silvestre, Ricardo. "Entrevista à Radio France Internationale acerca de "Post-acute Sequelae of COVID-19 is Characterized by diminished peripheral CD8+ß7+ T cells and Anti-SARS-CoV-2 IgA response"", Radio France Internationale, 2023
  2. Silvestre, Ricardo. "Molécula que pode prever a evolução dos doentes de Covid-19", ComUM, 2021, https://www.comumonline.com/2021/03/icvs-covid-19-ricardo-silvestre-ha-necessidade-de-criar-conhecimento-e-a-nossa-funcao-enquanto-investigadores-e-essa/.
  3. Silvestre, Ricardo. "Molécula IL-6 dá indicação da evolução dos doentes Covid", Correio do Minho, 2021, https://correiodominho.pt/noticias/molecula-il-6-da-indicacao-da-evolucao-dos-doentes-covid/129344.
  4. Silvestre, Ricardo. "A molécula que pode ajudar o SNS: IL-6 pode prever a evolução dos doentes com COVID-19", Raio X - Jornal Online de Saúde, 2021, https://raiox.pt/a-molecula-que-pode-ajudar-o-sns-il-6-pode-prever-a-evolucao-dos-doentes-com-covid-19/.
  5. Silvestre, Ricardo. "Medir regularmente a quantidade da molécula IL-6 ajuda a antecipar e combater a Covid-19", TSF, 2021, https://www.tsf.pt/portugal/sociedade/medir-regularmente-a-quantidade-da-molecula-il-6-ajuda-a-antecipar-e-combater-a-covid-19-13395009.html.
  6. Silvestre, Ricardo. "Parasita da leishmaniose torna-nos cúmplices da sua infecção", Público, 2013, https://www.publico.pt/2013/08/30/jornal/parasita-da-leishmaniose-tornanos-cumplices-da-sua-infeccao-27008571.
Preprint
  1. Domingues N; Gaifem J; Matthiesen R; Saraiva DP; Bento L; Marques AR; Soares MIL; et al. "Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causesin vitroandin vivoInflammation". 2023. http://europepmc.org/abstract/PPR/PPR615095.
    10.1101/2023.02.09.527823
  2. Mendes-Frias A; Gallo V; Iacobelli V; Gentile R; Antonini G; Silvestre R; Iacobelli S. "Galectin-3 binding protein stimulated IL-6 expression is impeded by antibody intervention in SARS-CoV-2 susceptible cell lines". 2022. http://europepmc.org/abstract/PPR/PPR476383.
    10.21203/rs.3.rs-1458420/v1
Thesis / Dissertation
  1. Silvestre, Ricardo Jorge Leal. "Leishmania SIR2 : host cell interactions and vaccinal approaches". PhD, 2007. http://hdl.handle.net/10216/64002.

Artistic / Performance

Program / Show
  1. RTP. 2021. "RTP". Portugal em Direto.

Intellectual property

Patent
  1. CT/EP2021/081014. 2021. "LGALS3BP as a diagnostic, prognostic, and therapeutic biomarker in COVID-19 and other cytokine storm conditions.". Portugal.
    Granted/Issued
  2. Silvestre, Ricardo. 2016. "Use of polymyxin as an antidote for intoxications by amatoxins (International Patent)".
  3. Silvestre, Ricardo. 2015. "Use of polymyxin as an antidote for intoxications by amatoxin (National Patent)". Portugal.
    Allowed
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/03/31 Immunometabolic networks during host-pathogen interactions XLVIII Annual Meeting of the Portuguese Society for Immunology
2022 Elucidation of the functional roles of lipid metabolism during visceral Leishmania infection 3rd International Caparica Conference on Leishmaniasis 2022, 24th–26th October 2022, Caparica, Portugal.
(Caparica, Portugal)
2021/12/09 Immunometabolic networks regulating host-pathogen interactions Unité INSERM U1141/NeuroDiderot Hôpital Robert DEBRÉ December 09, 2021, Paris, France.
2021/04/29 Biomarkers for predicting COVID-19 disease severity. International Immunology Day: Advances on the Immune Responses during COVID-19, April 29, 2021, Online
2019/06/12 Leishmaniose na Europa: da epidemiologia à pesquisa.
Universidade Federal da Bahia (Salvador, Brazil)
2019/05 Immunometabolic networks in the regulation of visceral leishmaniasis XLV Annual Meeting of the Portuguese Society for Immunology
(Coimbra, Portugal)
2018/06/08 Immunometabolic networks regulating host-pathogen interactions TOLL 2018 Editing Innate Immunity
(Porto, Portugal)
2018/04/27 Immunometabolic networks regulating host-pathogen interactions Seminars CICECO
CICECO - Universidade de Aveiro (Aveiro)
2018/04/09 Immunometabolic networks regulating host-pathogen interactions Seminars@CEDOC
CEDOC (Lisboa, Portugal)
2018/03 HIF-1a induction suppresses lipid accumulation in myeloid cells and protects against Leishmania donovani infection TwinnToInfect Spring School
(Sesimbra, Portugal)
2017/11/13 Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis. ICVS Ciência Falada.
(Braga, Portugal)
2017/11/09 Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis. VI PhDOC Annual Meeting
(Lisboa, Portugal)
2017/10/16 Modulation of host metabolism: new insights into immune evasion by Leishmania parasites International Conference “Immunometabolic Networks in the Regulation of Infection
(Lubeck, Germany)
2017/09/26 Lessons from live attenuated vaccines Summer School: Approaches for developing anti-Leishmania vaccines
I3S (Porto, Portugal)
2017/06 Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis ICVS Open Day
(Braga, Portugal)
2017/06 HIF-1a induction supresses lipid accumulation in myeloid cells and protects against Leishmania donovani infection XLIII Annual Meeting of the Portuguese Society of Immunology
(Porto, Portugal)
2017/06 Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis XLIII Annual Meeting of the Portuguese Society for Immunology
(Porto, Portugal)
2017/05/27 Modulation of host metabolism: new insights into immune evasion by Leishmania parasites XV Congress of the Sociedade Iberica de Citometria
Sociedad Ibérica de Citometria (Lisboa, Portugal)
2016/07/06 Metabolic reprogramming in macrophages: A role in infection and inflammation International Seminars
UC-Biotech - Cantanhede (Cantanhede, Portugal)
2015/10 IL-17 modulated macrophage metabolism: a role in cancer and inflammation. XLI Annual Meeting of the Portuguese Society for Immunology
(Braga, Portugal)
2015/09/15 AMPK on the core of host-pathogen metabolic coupling 2nd European Workshop on AMPK
(Maastricht, Netherlands)
2015/04/21 Metabolic modulation of the host: new perspectives on Leishmania evasion mechanisms 3º Congresso Nacional de Medicina Tropical e o 1º Congresso Lusófono de Doenças Transmitidas por Vetores. Instituto de Higiene e Medicina Tropical.
Instituto de Higiene e Medicina Tropical. (Lisboa, Portugal)
2015/02/09 Modulation of host metabolism: new insights into immune evasion by intracellular pathogens Ciência Falada
Universidade do Minho (Braga, Portugal)
2014/05/20 Cellular Metabolism and Immunological Evasion Conference on Oncobiology
Universidade do Porto Faculdade de Farmácia (Porto, Portugal)
2014 Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis. XL Annual Meeting of the Portuguese Society for Immunology XL Annual Meeting of the Portuguese Society for Immunology
(Lisboa, Portugal)
2013/06 Leishmania:Immunity ESCMID Postgraduate Technical Workshop Technical Workshop for Basic and Clinical Parasitology
(Porto, Portugal)
2013/05/28 Subvertion of host immune responses during Leishmania infection Ciência Falada
ICVS-Universidade do Minho (Braga, Portugal)
2013/05 Abortive T follicular helper differentiation and loss of activated memory B cells underlie the poor parasite-specific IgG production in Leishmania infantum-infected Rhesus macaques FIFTH WORLD CONGRESS ON LEISHMANIASIS - WorldLeish
(Porte de Galinhas, Brazil)
2013/05 A new antigen for serological diagnosis of asymptomatic canine leishmaniasis: from discovery to field application FIFTH WORLD CONGRESS ON LEISHMANIASIS - WorldLeish 5
(Porto de Galinhas, Brazil)
2013/05 Leishmania-infected mature dendritic cells polarize CD4+ T cells towards a non-protective T-bet+ INF+ IL10+ phenotype . FIFTH WORLD CONGRESS ON LEISHMANIASIS - WorldLeish 5
(Porto de Galinhas, Brazil)
2013/04/18 New Immunotherapeutic Strategies VII Jornadas Ciências Biomedicina
CESPU (Porto)
2013/02/18 Leishmania, tales of a successful protozoan parasite: new insights on immune response subversion during infection International Seminars
Instituto de Salud Carlos III (Madrid, Spain)
2012/05/24 Immunological response to leishmaniasis: from the murine model to human disease 2ªs Jornadas de Parasitologia
Escola Superior de Tecnologias de Saúde do Porto (Vila Nova de Gaia, Portugal)
2012/05 Leishmania-infected mature dendritic cells polarize CD4+ T cells towards a non-protective T-bet+ INF+ IL10+ phenotype EMBO|EMBL Symposium: New Perspectives on Immunity to Infection.
(Heidelberg, Germany)
2012/04/20 Estimating the post mortem interval through RNA and miRNA profiling. Congresso Crime do Século XXI
(Portugal)
2011/11 Infected but not Bystander Dendritic Cells polarize CD4+ T cells towards a non-protective T-bet+ INF-¿+ IL10+ phenotype XXXVII Annual Meeting of the Portuguese Society for Immunology "Portrait of the immune system: history and perspective
(Oeiras)
2011/10/26 Imunopatology of visceral leishmaniasis: current concepts and futures perspectives. Leishmanioses em Portugal no séx XXI. Leishmanioses em Portugal no Século XX
(Vila Real, Portugal)
2011/05/07 Recombinant Thiol Dependent Reductase 1 from Leishmania infantum induces protection against Visceral Leishmaniasis Second I3S Scientific Retreat IBMC/INEB/IPATIMUP together in science.
(Esposende, Portugal)
2010/03 Serological evaluation of experimentally infected dogs by LicTXNPX-ELISA and amastigote-flow cytometry Joint Expert Meeting between Working Groups 1 and 3 of the COST Action CM080
(Siena)
2009/09 PI3 kinase/AKT activation and NF-kappa B impairment: a strategy used by Leishmania parasites to impair DC function XXXV Annual Meeting of the Portuguese Society for Immunology
(Lisboa, Portugal)
2009/04 Leishmaniose: Novos métodos de prevenção, diagnóstico e tratamento.
Laboratório Nacional de Investigação Veterinária, (Porto, Portugal)
2009 Immunopathology of visceral leishmaniasis: progress and challenges 2nd IBMC scientific retreat
(Esposende, Portugal)
2008/10 Modulation of dendritic cells functions by Leishmania excreted/secreted proteins. XXXIV Annual Meeting of the Portuguese Society for Immunology
(Porto, Portugal)
2008/03 Immunological role of Leishmania secreted and nonsecreted antigens BSP Spring, Trypanosomiasis/Leishmaniasis and Malaria meeting
(Newcastle, United Kingdom)
2006/10 Attenuated SIR2-deficient Leishmania infantum as a vaccine candidate XXXII Annual Meeting of the Portuguese Society for Immunology
(Braga, Portugal)
2006/09 Altered virulence of L. infantum SIR2 single knockout-mutant: evaluation of its potential use as a vaccine candidate 16th European Congress of Immunology
(Paris, France)
2006/08 Leishmania cytosolic SIR2 deacetylase induces selective murine B-cell activation in vitro and in vivo 11th International Congress of Parasitology, ICOPA XI
(Glasgow, United Kingdom)
2006/05/08 Comparative study of the cytokine production in vitro and in vivo of three proteins involved in the trypanothione cascade II Simpósio Nacional de Citocinas
(Coibmra)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01/01 - Current Metabolic Immunotherapies to overcome T cell dysfunction in Canine Leishmaniasis
Supervisor of Sónia Maria Barros Carvalho
 PhD in Health Sciences (PhD)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023/01 - Current Elucidation of the functional roles of lipid metabolism during canine leishmaniasis
Supervisor of Marta Alexandra Senra Araújo
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022/09 - Current The role of the effect of Lactobacillus on the phenotype induced by BCAA supplementation in Ulcerative Colitis
Supervisor of Maria Catarina Freitas Vieira
Universidade de Coimbra, Portugal
2021/09 - Current Malignant ascites microenvironment kinetics during ovarian cancer metastization: comprehension of therapeutic resistances
Co-supervisor of Diana Luísa de Almeida Nunes
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/01 - Current Micronutrient sensing in human pathogenic parasites
Co-supervisor of Teresa Pires de Matos Alves Leão
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/01 - Current Immunometabolic pathways underlying resistance or susceptibility to Mycobacterium tuberculosis infection
Co-supervisor of Consuelo Micheli
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020/01 - Current Immunometabolic Networks during dendritic cell-Leishmania interactions
Co-supervisor of Stephanie Maia Acuna
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/01 - Current Development of metabolically active immunomodulatory biomaterials (MAIBs) for the resolution of implant-related inflammation and promotion of tissue regeneration
Co-supervisor of Matias Cardoso
Universidade de Aveiro CICECO, Portugal
2019/01 - Current Profiling of RNA degradation and biochemistry changes for estimation of postmortem interval. Influence of age and environmental temperature
Co-supervisor of Maria Bernardes André
Universidade do Porto Faculdade de Medicina, Portugal
2018/09 - Current Therapeutic Potential of Branched-chain amino acids and succinate in Ulcerative Colitis
Supervisor of Ana Isabel Mendes Frias
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/01 - Current Reprogramming human arthritogenic T cells
Co-supervisor of Daniela Filipa Amaral Silva
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2017/06 - Current Immunometabolic Networks regulating visceral leishmaniasis
Supervisor of Carolina Alves Ferreira
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017/04 - Current Dissecting the immunometabolic crosstalk of IL-17A/F-induced macrophage reprogramming during infection
Supervisor of Inês Morais Mesquita
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/04 - Current Evaluation of metabolic biomarkers in canine visceral leishmaniasis
Co-supervisor
Universidade Federal da Bahia Escola de Medicina Veterinária e Zootecnia, Brazil
2021/08/01 - 2023/01/10 Targeting glycolysis in Leishmania therapy
Supervisor of Sónia Maria Barros Carvalho
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/01 - 2019/03/25 Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis
Supervisor of Joana Filipa Madureira Gaifem
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2019 Therapeutic potential of branched-chain amino acids and succinate in ulcerative colitis.
Supervisor
 Biologia (PhD)
Universidade do Minho, Portugal
2017/10 - 2018/10 Elucidating the impact of IL-17A/F in lung cancer
Co-supervisor of Nathalia Jacobsen Ferreira
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/06 - 2017/06 Impact of chronic inflammatory responses on the biology of monocytes/macrophages
Co-supervisor of Bruno Lima
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/12 - 2017/06 Macrophage-Leishmania nutrient flow: a fine tune that dictates the success of infection
Supervisor of Diana Raquel Bento Moreira
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2016/11 Plasmodium falciparum multidrug resistance protein 1 (PfMRP1) role in artemether-lumefantrine resistance
Co-supervisor of Miguel João Ferreira da Silva
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/02 - 2016/07 Immunopathological characterization of chemically induced colitis in mice from different animal houses
Supervisor of Andreia Araújo
Laboratório Associado ICVS 3B's, Portugal
2016/02 - 2016/07 Orchestration of NAD biosynthetic pathways in the functional reprogramming of macrophage metabolism
Supervisor of Joana Neves
Laboratório Associado ICVS 3B's, Portugal
2015/09 - 2016/06 Implication of amino acid metabolism in monocyte differentiation
Supervisor of Ana Catarina Novais Belinha
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2010/04 - 2014/12 Regulation of immunity to visceral Leishmania in a non-human primate model of infection
Co-supervisor of Vasco Manuel Teixeira Afonso Rodrigues
Doutoramento em Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/03 - 2014/07 Bioenergetics evaluation of inflammatory macrophages
Supervisor of Anabela Gonçalves
Laboratório Associado ICVS 3B's, Portugal
2013/09 - 2014/04 Estimating the post mortem interval by clinical chemistry
Supervisor
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/10 - 2012/09 Study of the cytokine profile during the acute phase of infection using murine models of resistance and susceptibility to leishmaniasis
Supervisor of Jorge Augusto Pereira
Universidade do Porto Faculdade de Ciências, Portugal
2011/10 - 2012/09 Analysis of post-translational modifications in macrophages infected by Leishmania infantum
Supervisor of Joana Requeijo
Universidade do Porto Faculdade de Ciências, Portugal
2011/10 - 2012/05 Role of microRNAs in the determination of post-mortem interval
Co-supervisor of Fernanda Patrícia Sampaio Silva
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2010/12 - 2012/04 Study of IL-12 family of cytokines during visceral leishmaniasis
Supervisor of Ana Luísa Robalo
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2010/10 - 2011/06 Modulatory activity of several defined culture mediums on Leishmania infantum virulence
Supervisor of Cátia Sofia Ramos Silva
Universidade do Porto Faculdade de Ciências, Portugal
2010/10 - 2011/06 Relevance of axenic culture in Leishmania biology
Supervisor of Ana Marina Amorim
Universidade do Porto Faculdade de Ciências, Portugal
2010/02 - 2010/10 Molecular mechanisms regulating apoptosis of antigen presenting cells during visceral leishmaniasis
Supervisor of Ana Sofia Ramos
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2007/10 - 2008/12 Innate immune responses to the excreted/secreted antigens of Leishmania
Co-supervisor of Mariana Resende Silva
Universidade do Porto Faculdade de Ciências, Portugal
2005/10 - 2006/06 Immunological studies of a new Leishmania infantum excreted/secreted protein
Co-supervisor of Ana Sofia Cabral
Universidade do Porto Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/04/20 - 2022/04/22 Annual Meeting Portuguese Society for Immunology, “At the crossroads of Human Immunology” (2022/04/20 - 2022/04/22)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Imunologia, Portugal
2020/05/20 - 2020/05/22 XLVI Annual Meeting Portuguese Society for Immunology, “Current challenges and emerging topics in immunology” (2020/05/20 - 2020/05/22)
Congress (Co-organisor)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/05/15 - 2019/05/17 XLV Annual Meeting Portuguese Society for Immunology, “Leaping forward translational immunology” (2019/05/15 - 2019/05/17)
Congress (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Medicina, Portugal
2015/10/25 - 2015/10/28 Portuguese Immunology Society Meeting (2015/10/25 - 2015/10/28)
Congress (Member of the Organising Committee)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/01 The role of host lipid metabolism in the regulation of host antifungal immunity
(Thesis) Main arguer
 Adrian Barnatiu (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/12 Células eucarióticas como fontes de biomateriais e materiais vivos
(Thesis) Main arguer
 Matilde Rodrigues Lagarto (Master)
Universidade de Aveiro, Portugal
2022/02 Evaluation of a mutation on 26S proteasome subunit of Plasmodium falciparum towards antimalarial resistance
Thesis Member
 Adriana Faria Gonçalves (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/10 Sex-based differences in T cell response
(Thesis) Arguer
 Juliana Gonçalves (PhD)
Universidade Nova de Lisboa, Portugal
2021/09/24 Toxicological mechanism of tramadol and tapentadol: biomedical and forensic insights from in vivo studies
Thesis Member
 Maria Joana Almeida Rodrigues Barbosa (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021/07 HLA epitope matching for allocation improvement in kidney transplantation,
(Thesis) Arguer
 Sandra Cristina Ribeiro Tafulo (PhD)
2019/10/31 Disclosing the zinc acquisition and homeostatic machinery of Leishmania parasites
(Thesis) Main arguer
 Teresa Pires de Matos Alves Leão (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2019/05 Alterações histopatológicas renais e oculares em cães em diferentes estadios clínicos de leishmaniose visceral naturalmente adquirida
(Thesis) Main arguer
 Rosaclea Chagas dos Santos (Master)
Universidade Federal da Bahia Escola de Medicina Veterinária e Zootecnia, Brazil
2018/06/15 Establishment of a three-dimensional in vitro model of air-blood barrier to assess the translocation of nanoparticles targeted to the lung
(Thesis) Main arguer
 Ana Margarida Costa (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/06 Research into the toxicological mechanisms of tramadol and tapentadol: clinical and forensic aspects
(Thesis) Main arguer
 Juliana da Conceição Fernandes de Faria (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2018/04 In vitro and In vivo Studies of proatherogenic effects induced by end-products of cholesteryl esters oxidation
(Thesis) Main arguer
 Neuza Luisa da Silva Domingues (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2017/12 Decoding the role of IL-10 in aging
(Thesis) Main arguer
 Ana Catarina Pires Martins (Master)
Universidade do Minho Escola de Ciências, Portugal
2017/09/22 Leishmania infantum extracellular material and human invariant natural killer T cells: a functional study
(Thesis) Main arguer
 Renata Belo da Costa (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/03 Canine Leishmaniasis: the role of hepatocytes and kupffer cells during Leishmania infantum infection
(Thesis) Main arguer
 Maria Armanda Viana Rodrigues (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016/05/16 Phenotypic and Target-based Strategies for Drug discovery in Trypanosomes
(Thesis) Main arguer
 Luís Gaspar (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/02 Adjuvant nanocarriers for Hepatitis B vaccine: Formulation design and mechanistic studies
(Thesis) Main arguer
 Sandra Cristina Campos de Jesus (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/06 Impact of differential Toll-like receptor recognition of Mycobacterium tuberculosis strains on the adaptive imune system
(Thesis) Main arguer
 Vânia Rita de Faria Cardoso (Master)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2011/10/11 Functional properties of human invariante natural killer T cells: from inflammation to tolerance
Thesis Member
 Lúcia de Fátima Moreira Teixeira (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2011/10 Determination of pyrethroid metabolites in urine
(Thesis) Main arguer
 Isabel Cristina Meneses Monteiro da Silva (Master)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/09/29 Effects of cocaine, morphine and their combination in the liver mitochondrial bioenergetics
(Thesis) Main arguer
 Lisbeth Elena Sousa e Silva (Master)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Association member

Society Organization name Role
2018/01/09 - Current European Society for Clinical Microbiology and Infectious Diseases Associate
2005/10/01 - Current Portuguese Society for Immunology Member of General Assembly

Committee member

Activity description
Role 		Institution / Organization
2023/05 - Current Member of the Course Committee of the Master's Program in Health Sciences
Member
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021 - Current President of the Supervisory Board
Director
 Sociedade Portuguesa de Imunologia, Portugal
2021 - Current Governing Bodies of the Portuguese Society for Immunology, President of the Supervisory Board
President / Vice-president
2021 - Current Adjunct Overseas Faculty in BLDE University, Vijayapura, Karnataka, India
Advisor / Consultant
 BLDE Deemed to be University, India
2019 - Current Electoral Commission (by designation) in the context of the elections for ICVS Director)
Member
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014/07/01 - Current Scientific Council
Member
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015 - 2021 Governing Bodies of the Portuguese Society for Immunology, Secretary for the General Assembly
Member

Conference scientific committee

Conference name Conference host
2017/10/16 - Current International Conference ¿Immunometabolic Networks in the Regulation of Infection
2022/04/20 - 2022/04/22 At the crossroads of Human Immunology XLVII Annual Meeting Portuguese Society for Immunology
2021/05/20 - 2021/05/22 Current challenges and emerging topics in immunology XLVI Annual Meeting Portuguese Society for Immunology
2019/05/15 - 2019/05/17 Leaping forward translational immunology XLV Annual Meeting Portuguese Society for Immunology,
2015/10/26 - 2015/10/28 From basic immunology to the latest clinical breakthroughs Portuguese Society of Immunology

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Immunometabolism: from basics to therapy, Advanced Course Immunometabolism: from basics to therapy (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/09 - Current Invited Assistant Professor, Curricular Unit Immunology (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018 - Current Forensic Microbiology, Master in Forensic Sciences (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Lecturer Fundamentals in Immunology (Curso de doutoramento (conclusão de unidades curriculares)) Laboratório Associado ICVS 3B's, Portugal
2014 - Current Fundamentals in Immunology and Infection (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2008 - Current Mecanismos de Imunização e Princípios Imunológicos de Vacinação Associação Nacional de Farmácias, Portugal
2020 - 2021 Integrated Master's Degree in Pharmaceutical Sciences - História da Farmácia Integrated Master Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Imunology - Degree in Biomedical Sciences (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Legal Medicine and Toxicology - Degree in Biomedical Sciences (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Immunology - Integrated Master's Degree in Dental Medicine (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Forensic Genetics - Degree in Forensic Genetics (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Specialization Post-Graduation Course in Forensic Genetics (Especialização pós-licenciatura)
2019 - 2019 Topics in Animal Health: Research Project Development (Especialização pós-licenciatura) Universidade Federal da Bahia, Brazil
2016/03 - 2018/06 Invited Assistant Professor Doutoramento em Ciências Biológicas Aplicadas à Saúde (Doutoramento) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2005 - 2018 Lecturer GABBA program (graduated program in areas of applied and basic research), Immunology course (Doutoramento) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012/10/01 - 2014/07/01 Invited Assistant Professor in Immunological Therapies Mestrado em Terapias Moleculares (Mestrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2012/10 - 2014/07 Invited Assistant Professor in Immunology and Parasitology Mestrado em Análises Clínicas (Mestrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/10/01 - 2013/06/01 Invited Assistant Professor for Laboratory Methodologies Licenciatura em Ciências Laboratoriais Forenses (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2011/10 - 2013/06 Invited Assistant Professor, Curricular Unit Project (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2007 - 2009 Lecturer Experimental Biology and Biomedicine PhD program (Doutoramento) CNC.IBILI, Portugal
2007/10 - 2008/03 Invited Professor, Curricular Unit Immunology (Licenciatura) Universidade do Porto Faculdade de Farmácia, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2023 - Current Grant Reviewer, Research Council of Exposome Institute of the University of Montpellier, France
Evaluator
2022 - Current Fondo Sectorial de Salud 2022, Uruguay, Grant Reviewer
Evaluator
2019 - Current ERC Starting Grant – 2019 - Remote Referee
Evaluator
 European Research Council
2019 - Current Graduate Women in Science - Grant Reviewer
Evaluator
 Graduate Women in Science
2017 - Current GID-IINFACTS 2017 Grants
Evaluator
 Cooperativa de Ensino Superior Politécnico e Universitário, Portugal Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
2015 - Current Grant Reviewer
Evaluator
 Israel Science Foundation, Israel Israel Science Foundation

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2013/08/30 "Parasita da leishmaniose torna-nos cúmplices da sua infecção" Leishmaniasis parasite makes us accomplices of the infection News related to the paper published on JI. Resende M et al. 2013(highlighted in journal) We have unravelled the mechanism by which Leishmania-infected MHCIIhigh dendritic cells, in an IL-12 dependent manner, polarize CD4+ T cells toward a nonprotective T-bet+IFN-g+IL-10+ phenotype, which are associated with chronicity of infection. Público

Journal scientific committee

Journal title (ISSN) Publisher
2013 - Current Frontiers in Immunology (1664-3224) Frontiers Media SA

Mentoring / Tutoring

Topic Student name
2010 - 2014 Participation in “Ciência Viva no Laboratório" Several
Distinctions

Award

2019 Innovation Projects in Traditional Food Products | FoodValorization and NewFood
2017 Best short presentation
Portuguese Society of Immunology., Portugal
2015 Best oral presentation
Portuguese Society of Immunology., Portugal
2004 Merit Award for graduation with 16/20 values
Universidade do Porto, Portugal