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Odilia Queiros is is an Associate Professor of Biochemistry at the University Institute of Health Sciences (IUCS) of CESPU. PhD in Biological Sciences (Sciences School of University of Minho, 2002/02/21), Master in Molecular Genetics (Sciences School of University of Minho, 1995) and BSc in Biochemistry (Sciences Faculty of University of Porto). Guest Editor in the Journal International Journal for Molecular Sciences and Pharmaceutics in MDPI AG. Published 36 articles in journals and has h-index 18 (Scopus Author ID: 6506717929) and 20 (Google Scholar ). Has 5 section(s) of books. Supervised 2 PhD thesis(es) and co-supervised 3. Supervised 11 MSc dissertation(s) and co-supervised 2. Has received 4 awards and/or honors. Participates and/or participated as Principal investigator in 5 project(s) and Researcher in 11 project(s). She is/was guest editor of three special issues in MDPI journals. Works in the area(s) of Medical and Health Sciences with emphasis on Health Sciences. Her research is focused in the study of cancer cell metabolism and in the antitumor activity of drugs acting on metabolic targets as well as on the study of molecular mechanisms associated with multidrug resistance (MDR) phenotype in cancer cells. Her research aims also to study the molecular mechanisms associated with microenvironment characterisitcs in cancer, namely associated to cancer cell metabolism and with the expression of pH regulators . The assessment of the role of MDR genes in the response to antitumor agents using in models of simple eukaryotes, such as yeast, for the heterologous expression of different variants of the genes, is also a research goal. More recently, she has being studying the potential use of chiral derivatives of flavonoids and xhantones as antitumor agents and their mechanism of action in cancer cells.
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Identification

Personal identification

Full name
Odilia Queiros
Gender
Female

Citation names

  • Queiros, Odilia
  • Queiros O

Author identifiers

Ciência ID
FF15-58EC-635A
ORCID iD
0000-0001-5912-3409
Scopus Author Id
Scopus Author ID: 6506717929

Addresses

  • Instituto Universitário de Ciências da Saúde. Rua Central de Gandra, 1317, 4585-116 , Gandra-Paredes, Paredes, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Biochemistry
Education
Degree Classification
2024/07 - 2024/07
Concluded
 21st Century Skills for Teachers and Students (Erasmus) (Postgraduate Certificate)
Europass Teacher Academy , Germany
2023/03/20 - 2023/03/24
Concluded
 Presentation skills for academics (Erasmus) (Outros)
Galway Language School, Ireland
2021/07/23 - 2021/07/23
Concluded
 Training in Active Learning: Effective Practice in the Battle for Evidence: Our Duty to Adopt Active Learning (Outros)
Instituto Universitário de Ciências da Saúde, Portugal
2002/02/21
Concluded
 Sciences (Doutoramento)
Universidade do Minho Escola de Ciências, Portugal
"Transport and utilization of dicarboxylic acids in the yeasts Kluyveromyces sp. and Saccharomyces cerevisiae: A physiologic, biochemical and genetic approach" (THESIS/DISSERTATION)
 approved unanimously
1995
Concluded
 Molecular Genetics (Mestrado)
Universidade do Minho Escola de Ciências, Portugal
"Physiologic and molecular studies of homologues of malic acid transporters in Kluyveromyces marxianus" (THESIS/DISSERTATION)
 Very Good
1992
Concluded
 Biochemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Molecular Distrophy linked to chromosome X: Molecular and biochemical studies to confirm the diagnosis" (THESIS/DISSERTATION)
 14
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2020/07/31 - Current Associate Professor (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal
Instituto Universitário de Ciências da Saúde, Portugal
2002/02/21 - 2020/07/31 Assistant Professor (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal
1993/10/03 - 2002/02/20 Assistant (University Teacher) Instituto Universitário de Ciências da Saúde, Portugal

Others

Category
Host institution 		Employer
2023/11 - Current Guest Editor in Pharmaceutics MDPI AG, Switzerland
2023/10 - Current Guest Editor in the Journal International Journal for Molecular Sciences MDPI AG, Switzerland
2021 - Current Editorial board of "Scientific Letters (ISSN 2795-5117)" https://publicacoes.cespu.pt/index.php/sl/index Instituto Universitário de Ciências da Saúde, Portugal
2021 - Current Member of Scientific Council of UNIPRO Instituto Universitário de Ciências da Saúde, Portugal
2002 - Current Member of Scientific Council Instituto Universitário de Ciências da Saúde, Portugal
2020/09 - 2022/10 Guest Editor of the journal Applied Sciences MDPI AG, Switzerland
2014/10/01 - 2021/07/31 Coordinator of the Master of Molecular Therapies Instituto Universitário de Ciências da Saúde, Portugal
2016/09/01 - 2020/07/31 Coordinator of the Course Biochemistry Instituto Universitário de Ciências da Saúde, Portugal
2007/09/01 - 2017/01/01 Coordinator of the Course Nutritional Sciences Instituto Universitário de Ciências da Saúde, Portugal
2007/10/01 - 2014/09/20 Coordination Committee of the Master in Molecular Therapies Instituto Universitário de Ciências da Saúde, Portugal
Projects

Contract

Designation Funders
2025 - Current Unravelling the mechanism of action of chiral derivatives of flavonoids in tumour cells and their role in the multidrug resistance phenotype
33d0b394-a873-4075-80f9-0e036e1c93c3
Principal investigator
Submitted
2024/04/19 - 2025/04/22 FlavScreen_GI2-CESPU-2023: Screening and unraveling the mechanism of action of chiral flavonoid derivatives with anticancer activity
FlavScreen_GI2-CESPU-2023
Principal investigator
Ongoing
2022/09/01 - 2023/09/01 Flav4Tumor - Studies of molecular mechanisms of flavonoid derivatives with potential antitumor activity
Flav4Tumor-GI2-CESPU-2022
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Ongoing
2021 - 2022 Antitumor and antimicrobial activities of chiral derivatives of xanthones and flavonoids.
ActivCHIRAL_PI2RL_IINFACTS_2021
Researcher
Concluded
2019 - 2021 Chiral derivatives of xanthones and flavonoids: synthesis and biological activity evaluation
CHIRALBIOACTIVE-PI-3RL-IINFACTS-2019
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2015/10 - 2020/05/01 Trans-Acids. Structural-functional studies of carboxylic acid transporters: Novel tools in production optimization using industrial microbes
Provided by PTCRIS: 143819
PTDC/BIA-MIC/5184/2014
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2014/02/01 - 2020 STRUCTURAL-FUNCTIONAL STUDIES OF CARBOXYLIC ACID TRANSPORTERS: NOVEL TOOLS IN PRODUCTION OPTIMIZATIONS USING INDUSTRIAL MICROBES
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F961662%F2013/PT
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 CENTRE OF MOLECULAR AND ENVIRONMENTAL BIOLOGY
UID/BIA/04050/2019
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2018 Unraveling the role of cell metabolism and tumor microenvironment in the molecular mechanisms of resistance in cancer
MetabRes_CESPU_2017CESPU
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2017 - 2018 Comparative study of tramadol and tapentadol toxicity: in vivo chronic exposure assays
ChronicTramTap_CESPU_2017
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2017 - 2018 Relating Monocarboxylate Transporters (MCTs) Expression to Macrophage Polarization in Oral Squamous Cell Carcinoma
MacrOral_CESPU_2017
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2016 - 2017 Tramadol and tapentadol: The role of the MRP2 transporter, toxicicity and pharmacogenetic constraints
TramTap-CESPU-2016
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2016 - 2017 Unravelling the molecular mechanisms involved in the inhibition of tumor proliferation and drug resistance by metabolic modulators
BioCat_CESPU_2016
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
2012/04/02 - 2015/09/30 MycoFat: Metabolic engineering of yeast fatty acids synthesis for biodiesel production
info:eu-repo/grantAgreement/FCT/COMPETE/120940/PT
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014 - 2015 Toxicologic effects of tramadol and tapentadol: an in vivo comparative study
TETT_CESPU_2014
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2011 - 2015 Populational studies in MDR1 genetic polymorphisms
03-GBMC_2011
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2011 - 2015 Using waste glycerol biodiesel derived for the synthesis of high-value compounds
02-GBMC_2011
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
2010 - 2011 Non-classical targeting and regulation of expression of GAPDH1 from K. marxianus
GAPDH-CESPU-2011
Researcher
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
2010 - 2011 Lactate production from an engineered Saccharomyces cerevisiae strain with improved ability to use glycerol
YeastFactory-CESPU-2010
Principal investigator
Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2003/04/01 - 2006/09/30 Engineering of Saccharomyces species able to remove malic acid under genetic control
info:eu-repo/grantAgreement/FCT/POCI/38106/PT
Researcher
Fundação para a Ciência e a Tecnologia
1996 - 2000 Isolation and characterization of yeasts: applications in enology
PAMAF 96.09.5554.0.
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
Concluded
1995 - 1999 Optimization of alcoholic fermentations: construction of Saccharomyces cerevisiae strains with ability to remove weak acids from fermentation media
PRAXIS 2/2.1/BIO/1068/95
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Baltazar, Fátima; Valente, Diana; Afonso, Julieta; Queirós, Odília; Granja, Sara. "New horizons on pH regulators as cancer biomarkers and targets for pharmacological intervention". In An Innovative Approach to Understanding and Treating Cancer: Targeting pH, 417-450. Elsevier, 2020.
    10.1016/b978-0-12-819059-3.00017-4
  2. Casal, Margarida; Queirós, Odília; Talaia, Gabriel; Ribas, David; Paiva, Sandra. "Carboxylic Acids Plasma Membrane Transporters in Saccharomyces cerevisiae". In Advances in Experimental Medicine and Biology, 229-251. Springer International Publishing, 2016.
    10.1007/978-3-319-25304-6_9
  3. Queiros, Odilia; Moreira, Roxana. "Carbon monoxide and cyanade (Monóxido de Carbono e Cianetos)". In Toxicologia Forense, edited by Dinis-Oliveira, Ricardo Jorge; Magalhaes, Teresa. Portugal, 2015.
    Published
  4. Barbosa, Joana; Faria, Juliana; Queiros, Odilia; Moreira, Roxana; Dinis-Oliveira, Ricardo Jorge. "Meconium as an alternative matrix in bioanalysis". In New sampling strategies in toxicology and therapeutic drug monitoring, edited by Future Science. 2015.
    Published
  5. Queiros, Odilia; Casal, Margarida; Ferreira, Pedro Moradas; Leão, Cecília. "PCR based strategy for gene disruption in Kluyvermyces lactis". In Non-Conventional Yeasts in Genetics, Biochemistry and Biotechnology, edited by Wolf, Klaus; Breunig, Karin D.; Barth, Gerold. Springer Berlin Heidelberg, 2003.
    Published
Conference abstract
  1. Sousa, João, Flávia Barbosa, Andrea Cunha, Maria Elizabeth Tiritan, e Odília Queirós; Sousa, João; Barbosa, Flávia; Cunha, Andrea; Tiritan, Maria Elizabeth; Queiros, Odilia. "Determinação Da Atividade Anti Tumoral De Derivados Quirais De Xantonas (Determination of antitumor activity of chiral xhantones derivatives)". Paper presented in RevSALUS - Revista Científica Internacional Da Rede Académica Das Ciências Da Saúde Da Lusofonia 4 (Sup):75, Porto, 2022.
    Published • https://doi.org/10.51126/revsalus.v4iSup.296
  2. Barbosa, Joana; Faria, Juliana; Leal, S; Nascimento, Ana Vanessa; Afonso, Luís Pedro; Moreira, Roxana; Pereira, Frederico ; et al. "O Tramadol e o Tapentadol causam Hepato e Necrotoxicidade em Ratos Wistar expostos subcronicamente a doses terapêuticas (Tramadol and Tapentadol Cause Hepato and Necrotoxicity in Wistar Rats Subchronically Exposed to Therapeutic Doses)". Paper presented in 3.ª Reunião da Rede Académica nas Ciências da Saúde da Lusofonia, 2020.
    Published
  3. Barbosa, Joana; Faria, Juliana; Leal, Sandra; Afonso, L. P.; Queiros, Odilia; Moreira, Roxana; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Acute administration of tramadol and tapentadol induces dose-dependent toxicity in Wistar rats, affecting both metabolizing and target organs". Paper presented in XLVII Reunião da Sociedade Portuguesa de Farmacologia, Coimbra, 2017.
    Published
  4. Barbosa, Joana; Faria, Juliana; Queiros, Odilia; Moreira, Roxana; Dinis-Oliveira, Ricardo Jorge. "Tramadol and Tapentadol comparative toxicity in Wistar rats". Paper presented in EUROTOX, Sevilha, 2016.
  5. João, Azevedo-Silva; Odília, Queirós; Young, Ko; Peter, Pedersen; Ana, Preto; Margarida, Casal. "Characterization of 3-bromopyruvate uptake in breast cancer cells". 2014.
    10.3389/conf.fphar.2014.61.00003
  6. Pacheco, A; Queirós, O; Preto, A; Pinheiro, C; Azevedo-Silva, J; Moreira, R; Pedro, M; Baltazar, F; Casal, M. "3-bromopyruvate cytotoxic effect in breast cancer cells is dependent of monocarboxylate transporters (MCT) expression and is enhanced by butyrate". 2012.
    10.1055/s-0032-1330817
  7. Silva, E; Casal, M; Paiva, S; Queirós, O. "Subcellular localization of the monocarboxylate transporter Mct1 tagged with the green fluorescence protein in different cancer cell lines". Heidelberg, 2012.
    10.1055/s-0032-1330825
  8. Valente, D; Cunha, A; Pinheiro, C; Baltazar, F; Moreira, R; Queirós, O. "Effect of efflux pumps expression and cell bioenergetics in the multidrug resistance phenotype in cancer cells". Heidelberg, 2012.
    10.1055/s-0032-1330830
  9. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Molecular and physiological characterization of monocarboxylic acids permeases in Kluyveromyces lactis". Paper presented in XXIth International Conference on Yeast Genetics and Molecular Biology, Gotemburgo, 2003.
  10. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Molecular studies on malic acid transport in the yeast Kluyveromyces marxianus". Paper presented in 27th Meetting of the FEBS and Pan-American Association Molecular Biology., 2001.
  11. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Kluyveromyces lactis heterologous gene expression improves the ability of Saccharomyces cerevisiae to use malate". Paper presented in XVII Small Meeting on Yeast Transport and Energetics (SMYTE), 1999.
  12. Queiros, Odilia; Casal, Margarida; Althoff, S.; Moradas-Ferreira, Pedro; Leão, Cecília. "Phenotypic characterisation of Kluyveromyces marxianus deficient mutants on malate transport". Paper presented in XV Small Meeting on Yeast Transport and Energetics (SMYTE), Morelos, 1997.
Conference poster
  1. Cláudia Pinto, Flávia Barbosa, Patrícia Silva, Daniela Pereira, Hassan Bousbaa, Odília Queirós, Madalena Pinto, Honorina. "Modification of nature-inspired flavones through conjugation with amino acids as potential ecological antitumor agents". Paper presented in Blue Think Conference 2023, 13th September, Matosinhos, Portugal, 2023.
  2. Cláudia Pinto; Barbosa, Flávia; Queiros, Odilia; Madalena Pinto; Cidade, Honorina; Tiritan, Maria Elizabeth. "Molecular modification of flavones through conjugation with amino acids to obtain new potential antitumor agents". Paper presented in CHIRALITY 2023, 33rd International Symposium on Chirality, Rome, Italy, 2023.
  3. Vieira J, Granja S, Barbosa-Matos C, Ko YH, Queirós O, Casal M, Baltazar F. "3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy". Paper presented in International Society of Cancer Metabolism 6th Annual Meeting, 2019.
  4. Cunha A, Silva D, Sarmento B, Queirós O. "Exploiting the antitumor activity of the metabolic modulators 3-BP, DCA and 2DG in a lung cancer model". Paper presented in International Society of Cancer Metabolism 6th Annual Meeting. Braga, 2019.
  5. Cunha A, Rocha AC, Silva D, Barbosa F, Sarmento B, Queirós O; Cunha, Andrea; Ana Catarina Rocha; Daniela Silva; Flávia Barbosa; Sarmento, Bruno; Queiros, Odilia. "Estudo da atividade antitumoral de inibidores glicolíticos em linhas celulares tumorais de pulmão (Study of the antitumor activity of glycolytic inhibitors in lung tumor cell lines.)". Paper presented in 1º Encontro Nacional de Jovens Investigadores em Oncologia, Porto, 2019.
  6. Cunha, Andrea; Ana Catarina Rocha; Daniela Silva; Barbosa, Flávia; Sarmento, Bruno; Queiros, Odilia. "Exploração da atividade antitumoral de inibidores glicolíticos em linhas celulares tumorais de pulmão".". Paper presented in 1º Encontro Nacional de Jovens Investigadores em Oncologia da Liga Portuguesa Contra o Cancro, 2019.
  7. Barbosa AM, Cunha A, Casal M, Queirós O.. "Comparison of 3-bromopyruvate effect in a parental and resistant breast cancer cell line.". Paper presented in XI Jornadas Científicas do Instituto Universitário de Ciências da Saúde/IV Congresso da Associação Portuguesa de Ciências Forenses, Porto, 2019.
  8. Barbosa J, Faria J, Leal S, Nascimento V, Afonso L.P, Queirós O, Moreira R, Pereira F, Carvalho F, Dinis-Oliveira RJ. "Sub-chronic administration of tramadol and tapentadol therapeutic doses induces neurotoxicity in Wistar rats,". Paper presented in XI Jornadas Científicas do Instituto Universitário de Ciências da Saúde/IV Congresso da Associação Portuguesa de Ciências Forenses, Centro de Congressos da Alfândega do Porto, Porto., 2019.
  9. Barbosa J, Faria J, Leal S, Nascimento V, Afonso L.P, Queirós O, Moreira R, Pereira F, Carvalho F, Dinis-Oliveira RJ. "Sub-chronic exposure to therapeutic doses of tramadol and tapentadol causes hepatoxicity in Wistar rats,". Paper presented in XI Jornadas Científicas do Instituto Universitário de Ciências da Saúde/IV Congresso da Associação Portuguesa de Ciências Forenses, Centro de Congressos da Alfândega do Porto, Porto, 2019.
  10. Valente D, Granja S, Baltazar F, Queirós O.. "Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy.". Paper presented in Encontro Ciência_2018, Lisboa, Portugal, 2018.
  11. Vieira J , Azevedo-Silva J , Preto A , Casal M, O Queirós. "3-Bromopyruvate in association with different extracellular conditions influence in monocarboxylates transporters expression in colorectal cancer cells". Paper presented in 3rd ASPIC International Congress. Fundação Calouste Gulbenkian, Lisbon, Portugal, 2018.
  12. Barbosa AM, Cunha A, Casal M, Queirós O. "Unravelling the molecular mechanisms underlying 3-bromopyruvate resistance in tumor cell lines". Paper presented in IsCAM Meeting, Bertinoro, 2017.
  13. Cannone S, Greco MR, Valente D, Baltazar F, Queirós O, Piccapane F, Caroppo R, Reshkin SJ, Cardone RA.. "Extracellular matrix (ecm) collagen i levels differentially modulate PDAC parenchymal cell (CPC) and cancer stem cell (CSC) acid-base regulation’". Paper presented in IsCAM Meeting, Bertinoro, 2017.
  14. Barbosa J, Faria J, Leal S, Afonso LP, Lobo J, Moreira R, Queirós O, Carvalho F, Dinis-Oliveira RJ. "Acute administration of tramadol and tapentadol induces dose-dependent hepato and nephrotoxicity in wistar rats". Paper presented in EUROTOX 2017 Congress, Bratislava, 2017.
  15. Barbosa J, Faria J, Leal S, Afonso LP, Lobo J, Moreira R, Queirós O, Carvalho F, Dinis-Oliveira RJ. "Tramadol and tapentadol cause brain, lung and heart toxicity in effective and maximum tolerated doses.". Paper presented in EUROTOX 2017 Congress, Bratislava, 2017.
  16. Barbosa J, Faria J, Moreira R, Queirós O, Carvalho F, Dinis-Oliveira RJ.. "A Comparative study of the toxicological effects and pharmacokinetics of tramadol and tapentadol". Paper presented in . UCIBIO Advisory Board Meeting, Lisboa,, 2017.
  17. Granja S, Azevedo-Silva J, Queirós O, Preto A, Baltazar F, Casal M.. "Targeting glycolysis in acute myeloid leukemia: therapeutic applications.". Paper presented in XIX Congresso Nacional de Bioquímica. Guimarães, Portugal, 2016.
  18. Barbosa J, Faria J, Queirós O, Moreira R, Dinis-Oliveira R.. "Tramadol and Tapentadol comparative toxicity in Wistar rats. EUROTOX". Paper presented in EUROTOX, Sevilla, 2016.
  19. Barbosa AM, Vieira J, Miranda J, Moreira R, Casal M, Queirós O.. "3-Bromopyruvate induces cytotoxicity and decreases migratory capacity in glioblastomas and colorectal cell lines .". Paper presented in 2nd ASPIC (Associação Portuguesa de Investigação em Cancro) International Congress, 2016.
  20. Martins D, Faria J, Gonçalves D, Carvalho F, Queirós O, Moreira R, Dinis-Oliveira R.J, Barbosa J. "Optimization of a Populational Study of the G-840A Polymorphism.". Paper presented in I congresso da Associação Portuguesa de Ciências Forenses & IV Congresso sobre o abuso e negligência de crianças, Porto,, 2016.
  21. Tavares-Valente D, Moreira R, Baltazar F, Queirós O.. "Influence of acidic microenvironment in tumor progression.". Paper presented in Cancer and Metabolism Conference, Robinson College, Cambrigde, UK., 2015.
  22. Barbosa J, Faria J, Queirós O, Moreira R, Carvalho F, Dinis-Oliveira RJ.. "In vitro pharmacokinetic insights into tramadol and tapentadol toxic effects". Paper presented in 51st Congress of the European Societies of Toxicology. Porto, 2015.
  23. Barbosa J, Faria J, Queirós O, Moreira R, Carvalho F, Dinis-Oliveira RJ.. "An in vitro comparative study of the toxicological effects of tramadol and tapentadol.". Paper presented in 51st Congress of the European Societies of Toxicology., 2015.
  24. Cunha A, Dinis R, Queirós O, Moreira R.. "Population Analysis and Functional Genetic Polymorphisms of C3435T and G2677T MDR1 Gene.". Paper presented in XXXIX Jornadas Portuguesas de Genética. Braga, Portugal., 2015.
  25. Soares-Silva I, Ribas D, Foskolou J, Barata B, Bessa D, Paiva S, Queirós O, Casal, M. "The Debaryomyces hansenii carboxylate transporters Jen1 homologues are functional in Saccharomyces cerevisiae.". Paper presented in MicroBiotec. Universidade de Évora, Évora, Portugal., 2015.
  26. Tavares-Valente D, Moreira R, Baltazar F, Queirós O.. "Influence of extracellular pH modulation on the bioenergetics of glioblastoma cells.". Paper presented in 1st ASPIC (Associação Portuguesa de Investigação em Cancro) International Congress. Fundação Calouste Gulbenkian. Lisbon, 2014.
  27. Barbosa AM, Miranda J, Moreira R, Casal M, Queirós O.. "3-Bromopyruvate induces citotoxicity and inhibits glycolysis and migratory capacity in glioblastomas and breast cancer.". Paper presented in 1st ASPIC (Associação Portuguesa de Investigação em Cancro) International Congress. Fundação Calouste Gulbenkian. Lisbon. Portugal., 2014.
  28. Valente D, Baltazar F, Moreira R, Queirós O.. "Exploiting cell metabolism in cancer therapy: Effect of bioenergetic modulators on tumor cell characteristics.". Paper presented in 4th International Society of Proton Dynamics in Cancer . Munich, Germany., 2013.
  29. Cunha A, Dinis R, Queirós O, Moreira R.. "Population Analysis and Functional Genetic Polymorphisms of CYP2D6*4 and CYP2C19*17 Cytochrome P450 and C3435T MDR1 Gene.". Paper presented in ESPT 2013. Second conference: Pharmacogenomics: From cell to clinic. Lisbon, Portugal, 2013.
  30. Valente D, Baltazar F, Moreira R, Queirós O.. "Multidrug resistance phenotype: pH regulation in breast cancer cells.". Paper presented in EMBO YSF, Lisbon, Portugal, 2013.
  31. Silva E, Casal M, Paiva S, Queirós O.. "Intracellular trafficking of MCT1-tagged GFP". Paper presented in EMBO YSF. Lisbon, Portugal., 2013.
  32. Pacheco A, Queirós O, Preto A, Pinheiro C, Azevedo-Silva J, Moreira R, Pedro M, Baltazar F, Casal M.. "3-bromopyruvate cytotoxic effect in breast cancer cells is dependent of monocarboxylate transporters (MCT) expression and is enhanced by butyrate.". Paper presented in Metabolism 2012. From signaling to disease. Heidelberg, Germany, 2012.
  33. Valente D, Baltazar F, Moreira R, Queirós O.. ". Effect of efflux pumps expression and cell bioenergetics in the multidrug resistance phenotype in cancer cells.". Paper presented in Metabolism 2012. From signaling to disease. Heidelberg, Germany., 2012.
  34. Silva E, Casal M, Paiva S, Queirós O.. "Subcellular localization of the monocarboxylate transporter Mct1 tagged with the green fluorescence protein in different cancer cell lines.". Paper presented in Metabolism 2012. From signaling to disease. Heidelberg, Germany, 2012.
  35. Pacheco A, Talaia G, Sá-Pessoa J, Bessa D, Gonçalves MJ, Moreira R, Paiva S, Casal M, Queirós O.. "Metabolic engineering of lactic acid production in yeast: the role of the monocarboxylate permeases Jen1 and Ady2.". Paper presented in XXXVII Jornadas Portuguesas de Genética. Lisboa, Portugal., 2012.
  36. Cunha A, Dinis R, Queirós O, Moreira R.. "Genotype and allele frequencies of CYP2D6*4 and CYP2C19*17 single nucleotide polymorphisms in a Portuguese Population.". Paper presented in XXXVII Jornadas Portuguesas de Genética. Lisboa, Portugal., 2012.
  37. Pacheco A, Queirós O, Preto A, Pinheiro C, Azevedo-Silva J, Moreira R, Pedro M, Baltazar F, Casal M.. "Butyric acid increases monocarboxylate transporters (MCT) expression and enhances the cytotoxicity of the anti-tumoral agent 3-bromopyruvate (3-BP) in breast cancer cells.". Paper presented in XXI Porto Cancer Meeting: Metabolism and Cancer - From Etiopathogenesis to Threrapy. Porto, Portugal., 2012.
  38. Valente D, Pinheiro C, Baltazar F, Casal M, Moreira R, Queirós O.. "Molecular mechanisms underlying multidrug resistance in cancer cells: targeting cell metabolism and pH regulation.". Paper presented in XXI Porto Cancer Meeting: Metabolism and Cancer - From Etiopathogenesis to Threrapy. Porto, Portugal., 2012.
  39. Bessa D, Paiva S, Moreira R, Casal M, Queirós O.. "Functional characterization of Yarrowia lipolytica gene family coding for carboxylic acids permeases homologues.". Paper presented in Small Meeting on Yeast Transport and Energetics, SMYTE. Merida, Mexico., 2011.
  40. Faria, Juliana; Joana Barbosa; Bousbaa, Hassan; Pedro Moradas-Ferreira; Queiros, Odilia; Roxana Falcão-Moreira; Faria J, Barbosa J, Silva T, Bousbaa H, Moradas-Ferreira P, Ferreira-da-Silva F, Queirós O, Falcão-Moreira R.. "Non-classical targeting and regulation of the expression of GAPDH1p from K. marxianus". Paper presented in XVII Congresso Nacional de Bioquímica, 15 ¿ 17 December 2010, Porto, Portugal., 2010.
  41. Pacheco A, Bessa D, Mendes T, Gonçalves MJ, Moreira R, Casal M, Queirós O.. "Lactic acid production in yeast is modulated by the expression of carboxylic acids permeases.". Paper presented in XVII Congresso Nacional de Bioquímica. Porto, Portugal., 2010.
  42. Lopes J, Bessa D, Paiva S, Casal M, Johansson B, Queirós O.. "Metabolic engineering of a Saccharomyces cerevisiae strain improved its citric acid production.". Paper presented in XXXV Jornadas de Genética. Braga, Portugal., 2010.
  43. Barata B, Foskolou Z, Bessa D, Pacheco A, Queirós O, Casal M, Soares-Silva I.. "Study of Jen1p homologs by heterologous expression in Saccharomyces cerevisiae.". Paper presented in National Congress MicroBiotec09. Vilamoura, Portugal., 2009.
  44. Faria JF, Barbosa MJ, Nascimento AV, Falcão-Moreira R, Queirós O, Bousbaa H.. "Study of the mitotic checkpoint competence in a medulloblastoma cell line.". Paper presented in XVI Congresso Nacional de Bioquímica, Açores, 2008.
  45. Queirós O, Pereira L, Paiva S, Moradas-Ferreira P, Casal M. ; Queiros, Odilia; Pereira, Leonor; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Kljen1 and Kljen2 are essencial for the transport of monocarboxylic and dicarboxylic acids in the yeast Kluyveromyces lactis.". Paper presented in Yeast Genetics and Molecular Biology Meeting.Princeton, USA., 2006.
  46. Pereira L, Queirós O, Paiva S, Moradas-Ferreira P, Casal M.. "Characterization of the lactate transport in the yeast Kluyveromyces lactis.". Paper presented in XIV Congresso Nacional de Bioquímica. Vilamoura-Portugal,, 2004.
  47. Queirós O, Casal M, Moradas-Ferreira P, Leão C. “. "Molecular and Physiological characterization of monocarboxylic acids permeases in the yeast Kluyveromyces lactis.". Paper presented in XXIth International Conference on Yeast Genetics and Molecular Biology. Gothemburg, Sweden., 2003.
  48. Almeida C, Queirós O, Wheals A, Teixeira JA, Moradas-Ferreira P.. "Acquisition of flocculation phenotype by Kluyveromyces marxianus when overexpressing GAP1 gene encoding an isoform of glyceraldehyde-3-phosphate dehydrogenase.". Paper presented in XIII Congresso Nacional de Bioquímica. Lisboa, Portugal, 2002.
  49. Queirós O, Casal M, Moradas-Ferreira P, Leão C. ; Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, P.; Leão, Cecília. "Molecular studies on a Kluyveromyces marxianus malate inducible plasma membrane protein..". Paper presented in YEAST 2001: XXth International Conference on Yeast Genetics and Molecular Biology. Praga, Czech Republic,, 2001.
  50. Queirós O, Casal M, Moradas-Ferreira P, Leão C.. "Cloning of Kluyveromyces sp. genes involved in malic acid transport and metabolism.". Paper presented in X International Symposium on Yeasts. Papendal, Arnhem, Netherlands,, 2000.
  51. Queirós O, Casal M, Moradas-Ferreira P, Leão C.. "Strategy for cloning the gene coding for a Kluyveromyces marxianus malate inducible plasma membrane protein.". Paper presented in XII Congresso Nacional de Bioquímica. Póvoa de Varzim, Portugal., 2000.
  52. Queirós O, Casal M, Moradas-Ferreira P, Leão C. ; Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Engineering of a Saccharomyces cerevisiae strain improves the ability to use malic acid".". Paper presented in XIX International Conference on Yeast Genetics and Molecular Biology. Rimini, Italy,, 1999.
  53. Queirós O, Casal M, Moradas-Ferreira P, Leão C.. "Cloning of the genes involved on the lactate, acetate and malate transport in the yeasts Saccharomyces cerevisiae and Kluyveromyces sp.". Paper presented in MICRO´99. Luso, Portugal, 1999.
  54. Queirós O, Casal M, Moradas-Ferreira P, Leão C.. "Characterization of Kluyveromyces marxianus mutants defective in malic acid transport.". Paper presented in X Congresso Nacional de Bioquímica. Braga, Portugal,, 1996.
  55. Queirós O, Casal M, Moradas-Ferreira P, Leão C. ; Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Isolation and characterization of Kluyveromyces marxianus deficient mutants on malate transport.". Paper presented in XVII International Conference on Yeast Genetics and Molecular Biology. Lisbon, Portugal,, 1995.
  56. Queirós O, Casal M, Moradas-Ferreira P, Leão C.. "Transport of malic acid in Kluyveromyces marxianus: obtention of mutants defected on the acid transport capacity". Paper presented in Congresso Luso-Espanhol de Bioquímica. Salamanca, Spain, 1994.
Encyclopedia entry
  1. Andrea Cunha; Silva, Patrícia M. A.; Sarmento, Bruno; Queiros, Odilia. "Targeting Glucose Metabolism to Overcoming Drug Resistance". In Scholarly Community Encyclopedia. MDPI, 2023.
    Published
Journal article
  1. Barbosa, Flávia; Araújo, Joana; Gonçalves, Virgínia M. F.; Palmeira, Andreia; Cunha, Andrea; Silva, Patrícia M. A.; Fernandes, Carla; et al. "Evaluation of Antitumor Activity of Xanthones Conjugated with Amino Acids". International Journal of Molecular Sciences 25 4 (2024): 2121. http://dx.doi.org/10.3390/ijms25042121.
    10.3390/ijms25042121
  2. Pereira-Vieira, J.; Weber, D.D.; Silva, S.; Barbosa-Matos, C.; Granja, S.; Reis, R.M.; Queirós, O.; Ko, Y.H.; Kofler, B.. "Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia.". Pharmaceutics (2024):
    Open access • Published • https://doi.org/10.3390/pharmaceutics16040442
  3. Cunha, Andrea; Silva, Patrícia M. A.; Sarmento, Bruno; Queirós, Odília. "Targeting Glucose Metabolism in Cancer Cells as an Approach to Overcoming Drug Resistance". Pharmaceutics 15 11 (2023): 2610. http://dx.doi.org/10.3390/pharmaceutics15112610.
    10.3390/pharmaceutics15112610
  4. Cunha, A., Silva, P., Rocha, A. C., & Queirós, O.. "Unravelling the Warburg effect: glycolytic inhibitors as promising agents in cancer therapy". Scientific Letters 1 1 (2023): 5.
    Published • https://doi.org/10.48797/sl.2023.116
  5. Diana Tavares-Valente; Stefania Cannone; Maria Raffaella Greco; Tiago Miguel Amaral Carvalho; Fátima Baltazar; Odília Queirós; Gennaro Agrimi; Stephan J. Reshkin; Rosa Angela Cardone. "Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell". Cancers (2023): https://doi.org/10.3390/cancers15153868.
    10.3390/cancers15153868
  6. de Almeida, Catarina Dias; Queirós, Odília. "Special Issue Novel Developments in the Bioproduction of Biochemicals and Biomaterials". Applied Sciences 12 20 (2022): 10631. http://dx.doi.org/10.3390/app122010631.
    10.3390/app122010631
  7. Andrea Cunha; Ana Catarina Rocha; Flávia Barbosa; Ana Baião; Patrícia Silva; Bruno Sarmento; Odília Queirós. "Glycolytic Inhibitors Potentiated the Activity of Paclitaxel and Their Nanoencapsulation Increased Their Delivery in a Lung Cancer Model". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14102021.
    10.3390/pharmaceutics14102021
  8. Azevedo-Silva, J.; Tavares-Valente, D.; Almeida, A.; Queirós, O.; Baltazar, F.; Ko, Y. H.; Pedersen, P. L.; Preto, A.; Casal, M.. "Cytoskeleton disruption by the metabolic inhibitor 3-bromopyruvate: implications in cancer therapy". Medical Oncology 39 9 (2022): http://dx.doi.org/10.1007/s12032-022-01712-0.
    10.1007/s12032-022-01712-0
  9. Rafael Domingues; Maryna Bondar; Inês Palolo; Odília Queirós; Catarina Dias de Almeida; M. Teresa Cesário. "Xylose Metabolism in Bacteria—Opportunities and Challenges towards Efficient Lignocellulosic Biomass-Based Biorefineries". Applied Sciences 11 17 (2021): 8112-8112. https://doi.org/10.3390/app11178112.
    10.3390/app11178112
  10. Diana Tavares-Valente; Bárbara Sousa; Fernando Schmitt; Fátima Baltazar; Odília Queirós. "Disruption of pH Dynamics Suppresses Proliferation and Potentiates Doxorubicin Cytotoxicity in Breast Cancer Cells". Pharmaceutics 13 2 (2021): 242-242. https://doi.org/10.3390/pharmaceutics13020242.
    10.3390/pharmaceutics13020242
  11. Barbosa, Joana; Faria, Juliana; Garcez, Fernanda; Leal, Sandra; Afonso, Luís Pedro; Nascimento, Ana Vanessa; Moreira, Roxana; et al. "Repeated Administration of Clinically Relevant Doses of the Prescription Opioids Tramadol and Tapentadol Causes Lung, Cardiac, and Brain Toxicity in Wistar Rats". Pharmaceuticals 14 2 (2021): 97. http://dx.doi.org/10.3390/ph14020097.
    10.3390/ph14020097
  12. Barbosa, Joana; Faria, Juliana; Garcez, Fernanda; Leal, Sandra; Afonso, Luís Pedro; Nascimento, Ana Vanessa; Moreira, Roxana; et al. "Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats". Pharmaceuticals 13 7 (2020): 149. http://dx.doi.org/10.3390/ph13070149.
    10.3390/ph13070149
  13. Pereira-Vieira, Joana; Azevedo-Silva, João; Preto, Ana; Casal, Margarida; Queirós, Odília. "MCT1, MCT4 and CD147 expression and 3-bromopyruvate toxicity in colorectal cancer cells are modulated by the extracellular conditions". Biological Chemistry 400 6 (2019): 787-799. http://dx.doi.org/10.1515/hsz-2018-0411.
    10.1515/hsz-2018-0411
  14. Tavares-Valente, Diana; Granja, Sara; Baltazar, Fátima; Queirós, Odília. "Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy". Journal of Cellular and Molecular Medicine 22 8 (2018): 3782-3794. http://dx.doi.org/10.1111/jcmm.13642.
    10.1111/jcmm.13642
  15. Faria, J.; Barbosa, J.; Moreira, R.; Queirós, O.; Carvalho, F.; Dinis-Oliveira, R.J.. "Comparative pharmacology and toxicology of tramadol and tapentadol". European Journal of Pain 22 5 (2018): 827-844. http://dx.doi.org/10.1002/ejp.1196.
    10.1002/ejp.1196
  16. Barbosa, Joana; Faria, Juliana; Leal, Sandra; Afonso, Luís Pedro; Lobo, João; Queirós, Odília; Moreira, Roxana; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Acute administration of tramadol and tapentadol at effective analgesic and maximum tolerated doses causes hepato- and nephrotoxic effects in Wistar rats". Toxicology 389 (2017): 118-129. http://dx.doi.org/10.1016/j.tox.2017.07.001.
    10.1016/j.tox.2017.07.001
  17. Faria, Juliana; Barbosa, Joana; Leal, Sandra; Afonso, Luís Pedro; Lobo, João; Moreira, Roxana; Queirós, Odília; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Effective analgesic doses of tramadol or tapentadol induce brain, lung and heart toxicity in Wistar rats". Toxicology 385 (2017): 38-47. http://dx.doi.org/10.1016/j.tox.2017.05.003.
    10.1016/j.tox.2017.05.003
  18. Granja, Sara; Tavares-Valente, Diana; Queirós, Odília; Baltazar, Fátima. "Value of pH regulators in the diagnosis, prognosis and treatment of cancer". Seminars in Cancer Biology 43 (2017): 17-34. http://dx.doi.org/10.1016/j.semcancer.2016.12.003.
    10.1016/j.semcancer.2016.12.003
  19. Barbosa, Joana; Faria, Juliana; Queirós, Odília; Moreira, Roxana; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Comparative metabolism of tramadol and tapentadol: a toxicological perspective". Drug Metabolism Reviews 48 4 (2016): 577-592. http://dx.doi.org/10.1080/03602532.2016.1229788.
    10.1080/03602532.2016.1229788
  20. Azevedo-Silva, J.; Queirós, O.; Baltazar, F.; Ulaszewski, S.; Goffeau, A.; Ko, Y. H.; Pedersen, P. L.; Preto, A.; Casal, M.. "The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside". Journal of Bioenergetics and Biomembranes 48 4 (2016): 349-362. http://dx.doi.org/10.1007/s10863-016-9670-z.
    10.1007/s10863-016-9670-z
  21. Faria, Juliana; Barbosa, Joana; Queirós, Odília; Moreira, Roxana; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge. "Comparative study of the neurotoxicological effects of tramadol and tapentadol in SH-SY5Y cells". Toxicology 359-360 (2016): 1-10. http://dx.doi.org/10.1016/j.tox.2016.06.010.
    10.1016/j.tox.2016.06.010
  22. Soares-Silva, Isabel; Ribas, David; Foskolou, Iosifina P.; Barata, Beatriz; Bessa, Daniela; Paiva, Sandra; Queirós, Odília; Casal, Margarida. "TheDebaryomyces hanseniicarboxylate transporters Jen1 homologues are functional inSaccharomyces cerevisiae". FEMS Yeast Research (2015): fov094. http://dx.doi.org/10.1093/femsyr/fov094.
    10.1093/femsyr/fov094
  23. Jorge Dinis-Oliveira, Ricardo; Magalhaes, Teresa; Queiros, Odilia; Proenca, Jorge; Moreira, Roxana; de Lourdes Bastos, Maria; Carvalho, Felix; et al. "Signs and Related Mechanisms of Ethanol Hepatotoxicity". Current Drug Abuse Reviews 8 2 (2015): 86-103. http://dx.doi.org/10.2174/1874473708666150916113352.
    10.2174/1874473708666150916113352
  24. Teixeira, JH; Silva, PMA; Faria, J; Ferreira, I; Duarte, P; Delgado, ML; Queirós, O; et al. "Clinicopathologic significance of BubR1 and Mad2 overexpression in oral cancer". Oral Diseases 21 6 (2015): 713-720. http://dx.doi.org/10.1111/odi.12335.
    10.1111/odi.12335
  25. Azevedo-Silva, J.Ã.; Queirós, O.; Ribeiro, A.; Baltazar, F.; Young, K.H.; Pedersen, P.L.; Pretoand, A.; et al. "The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH". Biochemical Journal 467 2 (2015): 247-258. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930804928&partnerID=MN8TOARS.
    10.1042/BJ20140921
  26. Baltazar, Fátima; Morais-Santos F; Azevedo-Silva, João; Queiros, Odilia; Preto, Ana; Casal, Margarida. "Monocarboxylate transporters as targets and mediators in cancer therapy response". Journal of Histology and Histopathology 29 12 (2014): 1511-1524.
    Published
  27. Tavares-Valente, Diana; Baltazar, Fátima; Moreira, Roxana; Queirós, Odília. "Cancer cell bioenergetics and pH regulation influence breast cancer cell resistance to paclitaxel and doxorubicin". Journal of Bioenergetics and Biomembranes 45 5 (2013): 467-475. http://dx.doi.org/10.1007/s10863-013-9519-7.
    10.1007/s10863-013-9519-7
  28. Barbosa, Joana; Faria, Juliana; Carvalho, Félix; Pedro, Madalena; Queirós, Odília; Moreira, Roxana; Dinis-Oliveira, Ricardo Jorge. "Hair as an alternative matrix in bioanalysis". Bioanalysis 5 8 (2013): 895-914. http://dx.doi.org/10.4155/bio.13.50.
    10.4155/bio.13.50
  29. Bessa, Daniela; Pereira, Filipa; Moreira, Roxana; Johansson, Björn; Queirós, Odília. "Improved gap repair cloning in yeast: treatment of the gapped vector withTaqDNA polymerase avoids vector self-ligation". Yeast 29 10 (2012): 419-423. http://dx.doi.org/10.1002/yea.2919.
    10.1002/yea.2919
  30. Pacheco, António; Talaia, Gabriel; Sá-Pessoa, Joana; Bessa, Daniela; Gonçalves, Maria José; Moreira, Roxana; Paiva, Sandra; Casal, Margarida; Queirós, Odília. "Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2". FEMS Yeast Research 12 3 (2012): 375-381. http://dx.doi.org/10.1111/j.1567-1364.2012.00790.x.
    10.1111/j.1567-1364.2012.00790.x
  31. Queirós, Odília; Preto, Ana; Pacheco, António; Pinheiro, Céline; Azevedo-Silva, João; Moreira, Roxana; Pedro, Madalena; et al. "Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate". Journal of Bioenergetics and Biomembranes 44 1 (2012): 141-153. http://dx.doi.org/10.1007/s10863-012-9418-3.
    10.1007/s10863-012-9418-3
  32. Casal, Margarida; Paiva, Sandra; Queirós, Odília; Soares-Silva, Isabel. "Transport of carboxylic acids in yeasts". FEMS Microbiology Reviews 32 6 (2008): 974-994. http://dx.doi.org/10.1111/j.1574-6976.2008.00128.x.
    10.1111/j.1574-6976.2008.00128.x
  33. Queirós, Odília; Pereira, Leonor; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Functional analysis of Kluyveromyces lactis carboxylic acids permeases: heterologous expression of KlJEN1 and KlJEN2 genes". Current Genetics 51 3 (2006): 161-169. http://dx.doi.org/10.1007/s00294-006-0107-9.
    10.1007/s00294-006-0107-9
  34. Almeida, C; Almeida, C.; Queirós, O.; Wheals, A.; Teixeira, J.; Moradas-Ferreira, P.. "Acquisition of flocculation phenotype by Kluyveromyces marxianus when overexpressing GAP1 gene encoding an isoform of glyceraldehyde-3-phosphate dehydrogenase". Journal of Microbiological Methods 55 2 (2003): 433-440. http://dx.doi.org/10.1016/s0167-7012(03)00189-1.
    10.1016/s0167-7012(03)00189-1
  35. Queirós, Odília; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "PCR-Based Method for the Construction of Gene Disruption Cassettes in Yeast". BioTechniques 31 2 (2001): 264-268. http://dx.doi.org/10.2144/01312bm05.
    10.2144/01312bm05
  36. Queiros, O.; Casal, M.; Althoff, S.; Moradas-Ferreira, P.; Leao, C.; Queirós, O.; Leão, C.. "Isolation and characterization of Kluyveromyces marxianus mutants deficient in malate transport". Yeast 14 5 (1998): 401-407. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032579810&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0061(19980330)14:5<401::AID-YEA234>3.0.CO;2-T
Magazine article
  1. Leão, Cecília; Rodrigues, Fernando José dos Santos; Paiva, Sandra; Queirós, Odília; Schuller, Dorit Elisabeth; Cássio, Fernanda; Cardoso, M. Helena; Casal, Margarida; Côrte-Real, Manuela. "Remoção zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras (Zymological removal of volatile and fixed acidity from musts and wines: from physiology to genetic manipulation of yeasts)", Boletim de Biotecnologia, 1997, http://hdl.handle.net/1822/2079.

Other

Other output
  1. 2022.06056.PTDC. Chiral Flavonoids: enantioselectivity and (bio)degradability as sustainable strategy to search for new potential anti-inflammatory and antitumor agents. Research Proposal submitted to FCT for funding. 2022 call. Not funded. Team member. 2022. Queiros, Odilia.
  2. PTDC/QUI-QOR/2731/2021. 2D-Lipid tags as biomolecular tools for breast cancer detection. Research proposal submitted to FCT for funding. Not funded. Co-PI. 2022. Queiros, Odilia.
  3. PTDC/QUI-QOR/2896/2021. Xanthones and flavonoids: chirality and (bio)degradability as sustainable strategy to search for new potential anti-inflammatory and antitumor agents.. Research proposal submitted to FCT for funding. Not funded. Team member. 2021. Queiros, Odilia.
  4. C494249136-00091878. Proteome profiling of urine samples and genetic determinants of Portuguese patients infected with SARS-CoV-2.. Research proposal submitted to FCT for funding. Not funded. Team member. 2020. Queiros, Odilia.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/09 Chiral derivatives of xanthones and flavonoids: synthesis and biological activity evaluation. IX Workshop IINFACTS. "Breaking the Boundaries Between the Research Lines". Gandra, PRD.
2018 Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy Seminars of ICVS-Medical School
2017/10 Role of ECM collagen I levels in regulating PDAC parenchymal cell (CPC) and cancer stem cell (CSC) metabolic plasticity. IsCAM Meeting, Bertinoro, Italy
2017/10 Mitochondrial and glycolytic inhibitors hamper cancer viability and enhance response to conventional chemotherapy. IsCAM Meeting, Bertinoro,, Italy
2017/02 Tramadol and tapentadol cause bioenergetic crisis and necrosis in the SH-SY5Y cell model. XLVII Reunião anual da Sociedade Portuguesa de Farmacologia (SPF), Coimbra
2017/02 Acute administration of tramadol and tapentadol induces dose-dependent toxicity in Wistar rats, affecting both metabolizing and target organs XLVII Reunião anual da Sociedade Portuguesa de Farmacologia (SPF), Coimbra, Portugal
2016/12 Transport of monocarboxylic acids in cancer cells: implications of short chain fatty acids and 3-bromopyruvate for cancer therapy XIX Congresso Nacional de Bioquímica. Guimarães
Sociedade Portuguesa de Bioquímica
2016/09 Transport of monocarboxylic acids in cancer cells: implications of short chain fatty acids and 3-bromopyruvate for cancer therapy. SMYTE 34 (Small Meeting in Yeast Transport and Energetics). Crete, Greece.
2016/07 Role of monocarboxylates transporters and pH regulators in tumor progression and drug resistance VI Workshop IINFACTS, Campus Académico de Gandra
2016/02 An in vitro comparative study of the toxicological effects of tramadol and tapentadol in a panel of cell lines. I congresso da Associação Portuguesa de Ciências Forenses & IV Congresso sobre o abuso e negligência de crianças, Porto,
2013/10 Characterization of 3-bromopyruvate uptake in breast cancer cells. 4th International Society of Proton Dynamics in Cancer . Munich, Germany.
2012 Transport of lactic acid across plasma membrane: implications in health and biotechnology. SMYTE30 (Small Meeting in Yeast Transport and Energetics). Salamanca, Spain.
2011/09 Enhancement of carboxylic acids production in yeast: The role of carboxylic acids permeases. International Yeast Model Convention 2010, a tribute to Piotr Slonimski. Rome, Italy
2009 Metabolic engineering of Saccharomyces cerevisiae for lactic and citric acids production from raw glycerol. XVII Jornadas de Biologia de Leveduras Professor N. van Uden. Braga,
2007 Functional Insulin Quantification upon its Nanoencapsulation Micro’07-Biotec’07-XXXIII JPG Lisboa,
2005 Functional analysis of carboxylic acids permeases of Kluyveromyces lactis. XXXII Jornadas Portuguesas de Genética. Vila Real
2005 Heterologous expression of Kluyveromyces lactis carboxylic acids permease genes in Saccharomyces cerevisiae. 13as Jornadas de Biologia de Leveduras "Professor Nicolau van Uden". Universidade de Trás os Montes e Alto Douro, Vila Real,
2000 Cloning of Kluyveromyces sp. genes involved in dicarboxylic acid transport and metabolism 8as Jornadas de Biologia de Leveduras Professor N. van Uden Madrid, Espanha.
1999/09 Kluyveromyces lactis heterologous gene expression improves the ability of Saccharomyces cerevisiae to use malate. XVII Small Meeting on Yeast Transport and Energetics (SMYTE). Cordoba, Spain.
1998 Phenotypic characterisation of Kluyveromyces marxianus deficient mutants on malate transport. XV Small Meeting on Yeast Transport and Energetics (SMYTE). San José de Vistahermosa, Morelos, México.
1997 Phenotypic characterization of Kluyveromyces marxianus mutants defectives in malic acid transport. 5as Jornadas de Biologia de Leveduras Professor N. van Uden. Viseu, Portugal
1995/06 Isolation and characterization of Kluyveromyces marxianus deficient mutants on malate transport. Conference on Yeast Genetics and Molecular Biology. Lisbon, Portugal

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/09 - Current Studies of molecular mechanisms of chiral derivatives of flavonoids with potential antitumor activity
Supervisor of Flávia Patrícia Ribeiro Barbosa
 ~Biomedical Sciences (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2019 - Current Role of monocarboxylate transporters in the resistance phenotype of acute leukemia: therapeutic implications
Co-supervisor
 Health Sciences (PhD)
Universidade do Minho Escola de Medicina, Portugal
2021/09/01 - 2022/11 Determination of the biological activity of synthesised chiral derivatives of xanthones and flavonoids
Supervisor
 Master in Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2021/09/01 - 2022 Unravelling the molecular mechanisms underlying antiglycolytic agents resistance in tumor cell lines
Supervisor
 Master in Molecular Biomedicine (Master)
Universidade de Aveiro, Portugal
2016 - 2022 Unravelling the role of cell metabolism and tumor microenvironment in the molecular mechanisms of cancer resistance
Supervisor
 Biomedical Sciences (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2017 - 2021 Comparative study of the toxicological effects and pharmacokinetics of tramadol and tapentdol: a forensic perspective
Co-supervisor
 Biomedicine (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2013 - 2018 The influence of cancer cell metabolism and microenvironment on tumor progression and drug resistance
Supervisor of Diana Maria Tavares Valente
 Ciências da Saúde (PhD)
Universidade do Minho Escola de Medicina, Portugal
2012 - 2018 Toxicological effects and pharmacodynamics of tramadol: clinical and forensic implications
Co-supervisor
 Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2017 Molecular Mechanisms Involved in 3-Bromopyruvate Effect in Colorectal Cancer Cell Lines
Supervisor
 Genética Molecular (Master)
Universidade do Minho Escola de Ciências, Portugal
2016 - 2017 Unravelling the molecular mechanisms underlying 3-bromopyruvate resistance in tumor cell lines
Supervisor
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2016 - 2017 Influência de polimorfismos nos transportadores MCT1 e MCT4 no efeito citotóxico do 3-bromopiruvato em células tumorais (Influence of polymorphisms in MCT1 and MCT4 transporters on the cytotoxic effect of 3-bromopyruvate on tumor cells)
Supervisor
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2012 - 2014 Análise Populacional e Funcional dos Polimorfismos Genéticos CYP2D6*4 e CYP2C19*17 do Citocromo P450 e C3435T do Gene MDR1 (Population and Functional Analysis of Cytochrome P450 and C3435T Genetic Polymorphisms CYP2D6*4 and CYP2C19*17 of the MDR1 Gene)
Co-supervisor
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2012 - 2013 Molecular mechanisms underlying multidrug resistance phenotype in cancer cells: targeting cellular bioenergetics and pH regulation
Supervisor
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2012 - 2013 Endocytosis and Intracellular Trafficking of Plasma Membrane Transporters in Mammalian Cells
Supervisor
 Genética Molecular (Master)
Universidade do Minho, Portugal
2011 - 2012 Metabolic engineering of the yeast Saccharomyces cerevisiae for citric acid and fatty acids production
Supervisor
 Genética Molecular (Master)
Universidade do Minho, Portugal
2011 - 2012 Avaliação da actividade antitumoral de inibidores glicolíticos. Papel dos transportadores de monocarboxilatos (MCTs) no mecanismo de acção (Evaluation of the antitumor activity of glycolytic inhibitors. Role of monocarboxylate transporters (MCTs) in the mechanism of action)
Supervisor
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2010 - 2011 Estudos fisiológicos e moleculares de homólogos de transportadores de ácidos carboxílicos em Yarrowia lipolytica (Physiological and molecular studies of homologues of carboxylic acid transporters in Yarrowia lipolytica)
Supervisor
 Genética Molecular (Master)
Universidade do Minho, Portugal
2007 - 2008 Análise do checkpoint mitótico em células tumorais (Mitotic checkpoint analysis in tumor cells)
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - 2006 Análise funcional de permeases de ácidos carboxílicos em Kluyveromyces lactis (Functional analysis of carboxylic acid permeases in Kluyveromyces lactis)
Supervisor
 Genética Molecular (Master)
Universidade do Minho, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/12 Targeting BRCA1 mediated DNA repair in pancreatic ductal adenocarcinoma therapy
(Thesis) Main arguer
 João Pedro da Costa Festa e Ventura Morais (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/10/30 Investigating the role of short-chain fatty acids in colorectal cancer: therapeutic implications
(Thesis) Arguer
 Sara Daniela Coelho Gomes (PhD)
Universidade do Minho Escola de Ciências, Portugal
2022/12/19 Unraveling the role of cell metabolism in the molecular mechanisms of resistance in cancer Encapsulation of glycolytic inhibitors in nanoparticles to increase their release in a lung cancer model
Supervisor
 Andrea Teixeira da Cunha (PhD)
Instituto Universitário de Ciências da Saúde, Portugal
2022 Targeting brca1-mediated dna repair in pancreatic ductal Adenocarcinoma therapy
(Thesis) Main arguer
 Adriana Ventura Gomes (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022 Improving neuroblastoma therapy with TAp73 targeting agents
(Thesis) Main arguer
 Mariana Pereira Fernandes da Silva (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 Determinação da Atividade Antitumoral de Derivados Quirais de Xantonas e Flavonoides (Determination of Antitumor Activity of Chiral Xanthone and Flavonoid Derivatives)
(Thesis) Main arguer
 Flávia Patrícia Ribeiro Barbosa (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022 Construção de Linhas Tumorais Resistentes a Agentes Antiglícolíticos para Avaliar o seu Efeito no Metabolismo e na Viabilidade Celular (Construction of Antiglycolytic Agents Resistant Tumor Cell Lines to Evaluate Their Effect on Metabolism and Cell Viability)
Supervisor
 Ana Catarina Gonçalves da Rocha (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/09/21 Improving neuroblastoma therapy with TAP73-Targeting agents
(Thesis) Main arguer
 Mariana Pereira Fernandes da Silva (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 Novos produtos biotecnológicos e serviços para a indústria do vinho (Novel biotechnologic products and services to wine industry)
(Thesis) Main arguer
 Maria Eugénia Gonçalves Vieira (PhD)
Universidade do Minho, Portugal
2018 Uncovering the role of acetate between monocarboxylate transporters and oncogene signalling pathways in colorectal cancer
(Thesis) Main arguer
 Sara Daniela Coelho Gomes (Master)
Universidade do Minho, Portugal
2017 Molecular Mechanisms Involved in 3-Bromopyruvate Effect in Colorectal Cancer Cell Lines
Supervisor
 Joana Margarida Pereira Vieira (Master)
Universidade do Minho, Portugal
2016 Influência dos polimorfismos dos genes MCT1 e MCT4 na sua expressão e na citotoxicidade do 3-bromopiruvato em células tumorais (Influence of MCT1 and MCT4 gene polymorphisms on their expression and on cytotoxicity of 3-bromopyruvate in tumor cells)
Supervisor
 Joana Miranda (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2016 Unravelling the molecular mechanisms underlying 3-bromopyruvate resistance in tumor cell lines
Supervisor
 Ana Margarida Barbosa (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2016 In vivo studies on the toxic effects of orellanine: search for efficient antidotes
(Thesis) Main arguer
 Mariana Azevedo Soares (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/06/25 Study of the mechanisms of transport and regulation of carboxylic acids in Candida albicans and Candida glabrata
(Thesis) Main arguer
 Sandra Marlene da Silva Mota (PhD)
Universidade do Minho, Portugal
2013 Intracellular Trafficking of Plasma Membrane Transporters in Mammalian Cells
Supervisor
 Elsa Daniela Silva (Master)
Universidade do Minho, Portugal
2013 Intracellular Molecular mechanisms underlying multidrug resistance phenotype in cancer cells: targeting cellular bioenergetics and pH regulation
Supervisor
 Diana Maria Tavares Valente (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2013 Structural-functional studies of carboxylic acids transporters: novel tools in production optimization using industrial microbes
(Thesis) Main arguer
 David Manuel Nogueira Ribas (Master)
Universidade do Minho, Portugal
2012 Metabolic engineering of the yeast Saccharomyces cerevisiae for citric acid and fatty acids production
Supervisor
 João Lopes (Master)
Universidade do Minho, Portugal
2012 Avaliação da actividade antitumoral de inibidores glicolíticos. Papel dos transportadores de monocarboxilatos (MCTs) no mecanismo de acção (Evaluation of the antitumor activity of glycolytic inhibitors. Role of monocarboxylate transporters (MCTs) in the mechanism of action)
Supervisor
 António Augusto Vieira Pacheco (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2012 Genetic engineering of Ashbya gossypii: Application of the Cre-loxP system for rescue and reuse of selection markers
(Thesis) Main arguer
 Cláudia Isabel Cristovão Dinis (Master)
Universidade do Minho, Portugal
2012 The MX4blaster cassette – a tool for multiple gene disruption in Saccharomyces cerevisiae
(Thesis) Main arguer
 Ângela Manuela Ribeiro de Carvalho (Master)
Universidade do Minho, Portugal
2012 Elucidation of insulin intestinal absorption mechanisms using in vitro intestinal cell models
President of the jury
 Ana Francisca Araújo (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2011 Análise da actividade do checkpoint mitótico em linhas celulares do cancro da cavidade oral (Analysis of mitotic checkpoint activity in oral cavity cancer cell lines)
President of the jury
 Irís Ferreira (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2011 Estudos fisiológicos e moleculares de homólogos de transportadores de ácidos carboxílicos em Yarrowia lipolytica (Physiological and molecular studies of homologues of carboxylic acid transporters in Yarrowia lipolytica)
Supervisor
 Daniela Sofia Bessa (Master)
Universidade do Minho, Portugal
2010/04/30 The transport of carboxylic acids in yeast: From physiology towards strctural-function characterization of permeases
(Thesis) Arguer
 Neide Marina Pereira Vieira (PhD)
Universidade do Minho, Portugal
2010 Insights into the function of Transthyretin in the peripheral nerve and bone biology
President of the jury
 Filipa Franquinho Ferreira (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2009 Degradação de corantes de aplicação têxtil por levedura e engenharia metabólica de Saccharomyces cerevisiae para biodegradação de corantes azo (Degradation of textile application dyes by yeast and metabolic engineering of Saccharomyces cerevisiae for biodegradation of azo dyes)
(Thesis) Main arguer
 Filipe Vasconcelos (Master)
Universidade do Minho, Portugal
2006 Análise funcional de permeases de ácidos carboxílicos de Kluyveromyces lactis (Functional analysis of carboxylic acids permeases in Kluyveromyces lactis)
Supervisor
 Leonor Pereira (Master)
Universidade do Minho, Portugal
2005/10/17 Produção de pectinase utilizando culturas contínuas de leveduras (Pectinase production using continuous cultures of yeasts)
Thesis Member
 Maria Catarina Marques Dias de Almeida (PhD)
Universidade do Minho, Portugal

Conference scientific committee

Conference name Conference host
2023/06/01 - 2023/06/02 II INTERNATIONAL CONGRESS OF UNIPRO RESEARCH UNIT
2022/04/07 - 2022/04/08 APCF-TOXRUN International Congress 2022
2022/04/07 - 2022/04/08 1º INTERNATIONAL CONGRESS OF UNIPRO RESEARCH UNIT
2019 - 2019 Forensic and clinic perspectives about human improvement and immortality (Os olhares clínico e forense sobre o melhoramento humano e a imortalidade) Instituto Universitário de Ciências da Saúde
2018 - 2018 Forensic and clinic perspectives about memory (Os olhares clínico e forense sobre a memória) Instituto Universitário de Ciências da Saúde
2008 - 2018 CSI Fronteira Ficção - Realidade (CSI boundary fiction-reality) Instituto Universitário de Ciências da Saúde
2017 - 2017 Os olhares clínico e forense no diagnóstico e tratamento de lesões (Clinical and forensic perspectives in the diagnosis and treatment of injuries) Instituto Universitário de Ciências da Saúde
2016 - 2016 Doenças infeciosas, emergentes, reemergentes e negligenciadas (Infectious, emerging, re-emerging, and neglected diseases) Instituto Universitário de Ciências da Saúde
2015 - 2015 Human Microbiome - Health and Disease" VI Congress in Nutrition Sciences Instituto Universitário de Ciências da Saúde
2010 - 2010 XVII Congresso Nacional de Bioquímica (XVII National Congress of Biochemistry) Sociedade Portuguesa de Bioquímica
2010 - 2010 Cataclismos e catástrofes (Cataclysms and catastrophes) Instituto Universitário de Ciências da Saúde
2009 - 2009 Ciência: A causa das coisas (Science: The Cause of Things) Instituto Universitário de Ciências da Saúde
2007 - 2007 BioRiscos: Reflexos dos desequilíbrios bioquímicos no homem e no ambiente (BioRisks: Reflections of biochemical imbalances in humans and in the environment) Instituto Universitário de Ciências da Saúde

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2021 - Current Evaluator of intern research projects funded by IUCS/CESPU
Evaluator
 Instituto Universitário de Ciências da Saúde, Portugal Cooperativa de Ensino Superior Politécnico e Universitário

Other jury / evaluation

Activity description Institution / Organization
2023 - Current Jury of the probatory year of the PhD thesis Tumor molecular profiling and non-invasive liquid biopsy to fine tune adrenocortical carcinoma (ACC) diagnosis of the student of the PhD program in Biomedical Sciences Sofia Borges Oliveira Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Distinctions

Award

2023 Annual Scientific Productivity Award
Instituto Universitário de Ciências da Saúde, Portugal
2022 PhD day CBAS, CESPU Best Oral Presentation
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Other distinction

2012 Honor of the Portuguese Society of Senology to the work published in the peer-review journal JBB "Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate"
2009 2nd best poster presentation in III Jornadas de Ciências, ISCS-N