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Amália S. Jurado received her Ph.D. degree in Biochemistry from the Faculty of Science and Technology, University of Coimbra, and is Assistant Professor since then in the same Faculty, Department of Life Sciences.She has been responsible for teaching undergraduate courses in Biochemistry, Biology and Toxicology as well as a course on Functional Lipidomics of the Master Degree in Biochemistry and Cell and Molecular Biology, having also participated in post-graduated programs in Pharmaceutical Sciences. She supervised six Ph.D. students and one post-doc student, holding FCT fellowsips, and has argued fifteen Ph.D. theses. As Leader of the “Membrane Toxicity Group” at the CNC - Center of Neurosciences and Cell Biology, from 2002 to 2011, her work was focused on i. the development of in vitro assays for toxicity assessment alternative to animal use; ii. investigation of the molecular mechanisms underlying the cytotoxic effects of xenobiotics from pharmaceutics and agrochemical industries; and iii. study of the effects of diet lipid manipulation on the susceptibility of mitochondria to chemotherapeutics. She has participated in the Organization Committee of the International Course on Toxicology, Survival or Death as a Matter of Fat, in 2010, and edited the book “A Toxicological/Pharmacological Approach to the Chemico-Biological Interactions at the Membrane Level”, Research Signpost, Transworld Research Network, 2013. As Principal investigator of the research team in the project PTDC/QUI-BIQ/103001/2008 – “Interaction of Lipoplexes with Cellular Membranes: a Biophysical Approach to Gene Delivery”, funded by the Portuguese Foundation for Science and Technology, 2009-2013, she has been involved in the generation and characterization of new nucleic acid delivery systems based on surfactants, cell penetrating peptides, lipids and polymers, towards their application in gene therapy approaches. . As member of the “Vectors and Gene Therapy Group” at the CNC, and responsible for the research line in “Membrane Structure and Dynamics”, she has been involved in projects regarding i. the development of a lipid membrane anti-cancer therapy, based on the delivery of small interference RNAs targeting key-enzymes of lipid metabolism in GBM cells; and ii. Identification of miRNAs abnormally expressed in glioblastoma (GBM) and their modulation in order to sensitize GBM stem and differentiated cells to new generation chemotherapeutics. With h-factor of 20, she has authored 63 full papers in international peer-reviewed journals and 9 international scientific book chapters, with 964 citations (Scopus) and has over 100 presentations in National and International Scientific Meetings.
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Identificação

Identificação pessoal

Nome completo
Amália Jurado

Nomes de citação

  • Jurado, Amália S.

Identificadores de autor

Ciência ID
031B-E463-2D42
ORCID iD
0000-0001-7095-5337

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
1992
Concluído
 Doutoramento em Bioquímica (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Termo-Adaptação Molecular da Membrana de Bacillus stearothermophilus" (TESE/DISSERTAÇÃO)
 Aprovado com distinção e louvor por unanimidade
1986
Concluído
 Mestrado de Biologia Celular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Crescimento e Alterações da Composição Lipídica da bactéria termofílica Bacillus stearothermophilus" (TESE/DISSERTAÇÃO)
 Muito Bom
1980
Concluído
 Biologia (Ramo Científico) (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"não aplicável" (TESE/DISSERTAÇÃO)
 18
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
1992 - Atual Professor Auxiliar (Docente Universitário) Universidade de Coimbra, Portugal
1986/03/19 - 1992/05/07 Assistente (Docente Universitário) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1981/02/19 - 1986/03/18 Assistente Estagiário (Docente Universitário) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1979/08/03 - 1981/02/18 Monitor (Docente Universitário) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projetos

Projeto

Designação Financiadores
2010/05/03 - Atual Interaction of Lipoplexes with Cellular Membranes: a Biophysical Approach to Gene Delivery
PTDC/QUIBIQ/ 103001/2008
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Morais, Catarina M.; Cardoso, Ana M.; Araújo, Ana Rita D.; Reis, Ana; Domingues, Pedro; Domingues, Maria Rosário M.; de Lima, Maria C. Pedroso; Jurado, Amália S.. "Stearoyl CoA Desaturase-1 Silencing in Glioblastoma Cells: Phospholipid Remodeling and Cytotoxicity Enhanced upon Autophagy Inhibition". International Journal of Molecular Sciences 23 21 (2022): 13014. http://dx.doi.org/10.3390/ijms232113014.
    10.3390/ijms232113014
  2. Jurado, Amália S.. "Improving pollutants environmental risk assessment using a multi model toxicity determination with in vitro, bacterial, animal and plant model systems: The case of the herbicide alachlor". Environmental Pollution 286 (2021): 117239-117239. http://dx.doi.org/10.1016/j.envpol.2021.117239.
    10.1016/j.envpol.2021.117239
  3. Jurado, Amália S.. "MiR-200c-based metabolic modulation in glioblastoma cells as a strategy to overcome tumor chemoresistance". Human Molecular Genetics (2021): http://dx.doi.org/10.1093/hmg/ddab193.
    10.1093/hmg/ddab193
  4. Jurado, Amália S.. "Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells". Nutrients 13 5 (2021): 1723-1723. http://dx.doi.org/10.3390/nu13051723.
    10.3390/nu13051723
  5. Jurado, Amália S.. "Differentiation of glioblastoma stem cells promoted by miR-128 or miR-302a overexpression enhances senescence-associated cytotoxicity of axitinib". Human Molecular Genetics 30 3-4 (2021): 160-171. http://dx.doi.org/10.1093/hmg/ddab011.
    10.1093/hmg/ddab011
  6. Cardoso, Ana M; Morais, Catarina M; Rebelo, Olinda; Tão, Hermínio; Barbosa, Marcos; Pedroso de Lima, Maria C; Jurado, Amália S. "Downregulation of long non-protein coding RNA MVIH impairs glioblastoma cell proliferation and invasion through an miR-302a-dependent mechanism". Human Molecular Genetics 30 1 (2021): 46-64. http://dx.doi.org/10.1093/hmg/ddab009.
    10.1093/hmg/ddab009
  7. Faria, Rúben; Albuquerque, Tânia; Neves, Ana R.; Bhatt, Himanshu; Biswas, Swati; Cardoso, Ana M.; Pedroso de Lima, Maria C.; Jurado, Amália S.; Costa, Diana. "Physicochemical characterization and targeting performance of triphenylphosphonium nano-polyplexes". Journal of Molecular Liquids 316 (2020): 113873. http://dx.doi.org/10.1016/j.molliq.2020.113873.
    10.1016/j.molliq.2020.113873
  8. Coutinho, Maria Francisca; Santos, Juliana Inês; S. Mendonça, Liliana; Matos, Liliana; Prata, Maria João; S. Jurado, Amália; Pedroso de Lima, Maria C.; Alves, Sandra. "Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach". International Journal of Molecular Sciences 21 16 (2020): 5732. http://dx.doi.org/10.3390/ijms21165732.
    10.3390/ijms21165732
  9. Silva, Francisco; Paulo, António; Pallier, Agnès; Même, Sandra; Tóth, Éva; Gano, Lurdes; Marques, Fernanda; et al. "Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics". Materials 13 3 (2020): 513. http://dx.doi.org/10.3390/ma13030513.
    10.3390/ma13030513
  10. Morais, C.M.; Cardoso, A.M.; Aguiar, L.; Vale, N.; Nóbrega, C.; Zuzarte, M.; Gomes, P.; Pedroso de Lima, M.C.; Jurado, A.S.. "Lauroylated Histidine-Enriched S413-PV Peptide as an Efficient Gene Silencing Mediator in Cancer Cells". Pharmaceutical Research 37 10 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85090147228&partnerID=MN8TOARS.
    10.1007/s11095-020-02904-x
  11. Morais, Catarina M; Cunha, Pedro P; Melo, Tânia; Cardoso, Ana M; Domingues, Pedro; Domingues, M Rosário; Pedroso de Lima, Maria C; Jurado, Amália S. "Glucosylceramide synthase silencing combined with the receptor tyrosine kinase inhibitor axitinib as a new multimodal strategy for glioblastoma". Human Molecular Genetics 28 21 (2019): 3664-3679. http://dx.doi.org/10.1093/hmg/ddz152.
    10.1093/hmg/ddz152
  12. Cardoso, Ana M S; Sousa, Madalena; Morais, Catarina M; Oancea-Castillo, Liliana R; Régnier-Vigouroux, Anne; Rebelo, Olinda; Tão, Hermínio; et al. "MiR-144 overexpression as a promising therapeutic strategy to overcome glioblastoma cell invasiveness and resistance to chemotherapy". Human Molecular Genetics 28 16 (2019): 2738-2751. http://dx.doi.org/10.1093/hmg/ddz099.
    10.1093/hmg/ddz099
  13. Morais, Catarina M.; Cardoso, Ana M.; Cunha, Pedro P.; Aguiar, Luísa; Vale, Nuno; Lage, Emílio; Pinheiro, Marina; et al. "Acylation of the S413-PV cell-penetrating peptide as a means of enhancing its capacity to mediate nucleic acid delivery: Relevance of peptide/lipid interactions". Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 12 (2018): 2619-2634. http://dx.doi.org/10.1016/j.bbamem.2018.10.002.
    10.1016/j.bbamem.2018.10.002
  14. Carvalho, Filipa S.; Morais, Catarina M.; Holy, Jon; Krasutsky, Dmytro; Yemets, Sergiy V.; Krasutsky, Pavel A.; Jurado, Amália S.; Oliveira, Paulo J.; Serafim, Teresa L.. "Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains". Chemico-Biological Interactions 296 (2018): 198-210. http://dx.doi.org/10.1016/j.cbi.2018.10.002.
    10.1016/j.cbi.2018.10.002
  15. Araújo, Ana Rita D.; Melo, Tânia; Maciel, Elisabete A.; Pereira, Clara; Morais, Catarina M.; Santinha, Deolinda R.; Tavares, Joana F.; et al. "Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast". PLOS ONE 13 8 (2018): e0202402. http://dx.doi.org/10.1371/journal.pone.0202402.
    10.1371/journal.pone.0202402
  16. Cunha, P.P.; Costa, P.M.; Morais, C.M.; Lopes, I.R.; Cardoso, A.M.; Cardoso, A.L.; Mano, M.; Jurado, A.S.; Pedroso De Lima, M.C.P.. "High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors". Human Molecular Genetics 26 22 (2017): 4375-4387. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034256071&partnerID=MN8TOARS.
    10.1093/hmg/ddx323
  17. Cruz, R.Q.; Morais, C.M.; Cardoso, A.M.; Silva, S.G.; Vale, M.L.; Marques, E.F.; Pedroso De Lima, M.C.; Jurado, A.S.. "Enhancing glioblastoma cell sensitivity to chemotherapeutics: A strategy involving survivin gene silencing mediated by gemini surfactant-based complexes". European Journal of Pharmaceutics and Biopharmaceutics 104 (2016): 7-18. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964330230&partnerID=MN8TOARS.
    10.1016/j.ejpb.2016.04.014
  18. Cardoso, A.M.; Morais, C.M.; Cruz, A.R.; Silva, S.G.; Do Vale, M.L.; Marques, E.F.; De Lima, M.C.P.; Jurado, A.S.. "New serine-derived gemini surfactants as gene delivery systems". European Journal of Pharmaceutics and Biopharmaceutics 89 (2015): 347-356. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920830778&partnerID=MN8TOARS.
    10.1016/j.ejpb.2014.12.013
  19. Cardoso, A.M.; Morais, C.M.; Cruz, A.R.; Cardoso, A.L.; Silva, S.G.; Do Vale, M.L.; Marques, E.F.; Pedroso De Lima, M.C.; Jurado, A.S.. "Gemini Surfactants Mediate Efficient Mitochondrial Gene Delivery and Expression". Molecular Pharmaceutics 12 3 (2015): 716-730. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924023696&partnerID=MN8TOARS.
    10.1021/mp5005349
  20. Monteiro, J.P.; Morais, C.M.; Oliveira, P.J.; Jurado, A.S.. "Mitochondrial membrane lipids in life and death and their molecular modulation by diet: Tuning the furnace". Current Drug Targets 15 8 (2014): 797-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904720484&partnerID=MN8TOARS.
    10.2174/1389450115666140623115315
  21. Cardoso, A.M.; Calejo, M.T.; Morais, C.M.; Cardoso, A.L.; Cruz, R.; Zhu, K.; Pedroso De Lima, M.C.; Jurado, A.S.; Nyström, B.. "Application of thermoresponsive PNIPAAM-b-PAMPTMA diblock copolymers in siRNA delivery". Molecular Pharmaceutics 11 3 (2014): 819-827. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901742907&partnerID=MN8TOARS.
    10.1021/mp400510a
  22. Santos, S.M.; Dinis, A.M.; Peixoto, F.; Ferreira, L.; Jurado, A.S.; Videira, R.A.. "Interaction of fullerene nanoparticles with biomembranes: From the partition in lipid membranes to effects on mitochondrial bioenergetics". Toxicological Sciences 138 1 (2014): 117-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894311599&partnerID=MN8TOARS.
    10.1093/toxsci/kft327
  23. Santos, S.M.A.; Videira, R.A.; Fernandes, M.A.S.; Santos, M.S.; Moreno, A.J.M.; Vicente, J.A.F.; Jurado, A.S.. "Toxicity of the herbicide linuron as assessed by bacterial and mitochondrial model systems". Toxicology in Vitro 28 5 (2014): 932-939. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900019220&partnerID=MN8TOARS.
    10.1016/j.tiv.2014.04.004
  24. Cardoso, A.M.; Morais, C.M.; Silva, S.G.; Marques, E.F.; De Lima, M.C.P.; Jurado, M.A.S.. "Bis-quaternary gemini surfactants as components of nonviral gene delivery systems: A comprehensive study from physicochemical properties to membrane interactions". International Journal of Pharmaceutics 474 1-2 (2014): 57-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906267891&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2014.08.011
  25. Cardoso, A.M.; Trabulo, S.; Cardoso, A.L.; Maia, S.; Gomes, P.; Jurado, A.S.; Pedroso De Lima, M.C.. "Comparison of the efficiency of complexes based on S413-PV cell-penetrating peptides in plasmid DNA and siRNA delivery". Molecular Pharmaceutics 10 7 (2013): 2653-2666. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879735661&partnerID=MN8TOARS.
    10.1021/mp400078h
  26. Monteiro, J.P.; Oliveira, P.J.; Jurado, A.S.. "Mitochondrial membrane lipid remodeling in pathophysiology: A new target for diet and therapeutic interventions". Progress in Lipid Research 52 4 (2013): 513-528. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884316964&partnerID=MN8TOARS.
    10.1016/j.plipres.2013.06.002
  27. Monteiro, J.P.; Silva, A.M.; Jurado, A.S.; Oliveira, P.J.. "Rapeseed oil-rich diet alters in vitro menadione and nimesulide hepatic mitochondrial toxicity". Food and Chemical Toxicology 60 (2013): 479-487. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883398418&partnerID=MN8TOARS.
    10.1016/j.fct.2013.07.073
  28. Santos, S.M.A.; Dinis, A.M.; Rodrigues, D.M.F.; Peixoto, F.; Videira, R.A.; Jurado, A.S.. "Studies on the toxicity of an aqueous suspension of C60 nanoparticles using a bacterium (gen. Bacillus) and an aquatic plant (Lemna gibba) as in vitro model systems". Aquatic Toxicology 142-143 (2013): 347-354. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885129407&partnerID=MN8TOARS.
    10.1016/j.aquatox.2013.09.001
  29. Calejo, M.T.; Cardoso, A.M.S.; Kjøniksen, A.-L.; Zhu, K.; Morais, C.M.; Sande, S.A.; Cardoso, A.L.; et al. "Temperature-responsive cationic block copolymers as nanocarriers for gene delivery". International Journal of Pharmaceutics 448 1 (2013): 105-114. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875930565&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2013.03.028
  30. Monteiro, J.P.; Pereira, C.V.; Silva, A.M.; Maciel, E.; Baldeiras, I.; Peixoto, F.; Domingues, M.R.; Jurado, A.S.; Oliveira, P.J.. "Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics". Archives of Toxicology (2013): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876755736&partnerID=MN8TOARS.
    10.1007/s00204-013-1068-7
  31. Monteiro, J.P.; Martins, A.F.; Nunes, C.; Morais, C.M.; Lúcio, M.; Reis, S.; Pinheiro, T.J.T.; et al. "A biophysical approach to menadione membrane interactions: Relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects". Biochimica et Biophysica Acta - Biomembranes 1828 8 (2013): 1899-1908. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877072697&partnerID=MN8TOARS.
    10.1016/j.bbamem.2013.04.006
  32. Trabulo, S.; Cardoso, A.L.; Cardoso, A.M.S.; Morais, C.M.; Jurado, A.S.; Pedroso de Lima, M.C.. "Cell-penetrating peptides as nucleic acid delivery systems: From biophysics to biological applications". Current Pharmaceutical Design 19 16 (2013): 2895-2923. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878655380&partnerID=MN8TOARS.
    10.2174/1381612811319160006
  33. Kjøniksen, A.-L.; Calejo, M.T.; Zhu, K.; Cardoso, A.M.S.; de Lima, M.C.P.; Jurado, A.S.; Nyström, B.; Sande, S.A.. "Sustained Release of Naltrexone from Poly(N-Isopropylacrylamide) Microgels". Journal of Pharmaceutical Sciences (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887263499&partnerID=MN8TOARS.
    10.1002/jps.23780
  34. Calejo, M.T.; Cardoso, A.M.S.; Marques, E.F.; Araújo, M.J.; Kjøniksen, A.-L.; Sande, S.A.; de Lima, M.C.P.; Jurado, A.S.; Nyström, B.. "In vitro cytotoxicity of a thermoresponsive gel system combining ethyl(hydroxyethyl) cellulose and lysine-based surfactants". Colloids and Surfaces B: Biointerfaces 102 (2013): 682-686. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867835593&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2012.09.033
  35. Silva, S.G.; Alves, C.; Cardoso, A.M.S.; Jurado, A.S.; Pedroso De Lima, M.C.; Vale, M.L.C.; Marques, E.F.. "Synthesis of gemini surfactants and evaluation of their interfacial and cytotoxic properties: Exploring the multifunctionality of serine as headgroup". European Journal of Organic Chemistry 9 (2013): 1758-1769. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875008251&partnerID=MN8TOARS.
    10.1002/ejoc.201201396
  36. Trabulo, S.; Cardoso, A.L.; Cardoso, A.M.S.; Düzgünes, N.; Jurado, A.S.; De Lima, M.C.P.. "Cell-penetrating peptide-based systems for nucleic acid delivery: A biological and biophysical approach". Methods in Enzymology 509 (2012): 277-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860744340&partnerID=MN8TOARS.
    10.1016/B978-0-12-391858-1.00014-9
  37. Calejo, M.T.; Kjoniksen, A.-L.; Pinazo, A.; Pérez, L.; Cardoso, A.M.S.; Pedroso De Lima, M.C.; Jurado, A.S.; Sande, S.A.; Nyström, B.. "Thermoresponsive hydrogels with low toxicity from mixtures of ethyl(hydroxyethyl) cellulose and arginine-based surfactants". International Journal of Pharmaceutics 436 1-2 (2012): 454-462. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865288628&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2012.07.018
  38. Cardoso, A.M.S.; Trabulo, S.; Cardoso, A.L.; Lorents, A.; Morais, C.M.; Gomes, P.; Nunes, C.; et al. "S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: Implications for cell internalization". Biochimica et Biophysica Acta - Biomembranes 1818 3 (2012): 877-888. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856059612&partnerID=MN8TOARS.
    10.1016/j.bbamem.2011.12.022
  39. Cardoso, A.M.S.; Faneca, H.; Almeida, J.A.S.; Pais, A.A.C.C.; Marques, E.F.; De Lima, M.C.P.; Jurado, A.S.. "Gemini surfactant dimethylene-1,2-bis(tetradecyldimethylammonium bromide)-based gene vectors: A biophysical approach to transfection efficiency". Biochimica et Biophysica Acta - Biomembranes 1808 1 (2011): 341-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649777308&partnerID=MN8TOARS.
    10.1016/j.bbamem.2010.09.026
  40. Monteiro, J.P.; Martins, A.F.; Lúcio, M.; Reis, S.; Geraldes, C.F.G.C.; Oliveira, P.J.; Jurado, A.S.. "Interaction of carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) with lipid membrane systems: A biophysical approach with relevance to mitochondrial uncoupling". Journal of Bioenergetics and Biomembranes 43 3 (2011): 287-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959768623&partnerID=MN8TOARS.
    10.1007/s10863-011-9359-2
  41. Monteiro, J.P.; Martins, A.F.; Lúcio, M.; Reis, S.; Pinheiro, T.J.T.; Geraldes, C.F.G.C.; Oliveira, P.J.; Jurado, A.S.. "Nimesulide interaction with membrane model systems: Are membrane physical effects involved in nimesulide mitochondrial toxicity?". Toxicology in Vitro 25 6 (2011): 1215-1223. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960964709&partnerID=MN8TOARS.
    10.1016/j.tiv.2011.05.014
  42. Almeida, J.A.S.; Marques, E.F.; Jurado, A.S.; Pais, A.A.C.C.. "The effect of cationic gemini surfactants upon lipid membranes. An experimental and molecular dynamics simulation study". Physical Chemistry Chemical Physics 12 43 (2010): 14462-14476. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049386886&partnerID=MN8TOARS.
    10.1039/c0cp00950d
  43. Pinto, M.F.V.; Morán, M.C.; Miguel, M.G.; Lindman, B.; Jurado, A.S.; Pais, A.A.C.C.. "Controlling the morphology in DNA condensation and precipitation". Biomacromolecules 10 6 (2009): 1319-1323. http://www.scopus.com/inward/record.url?eid=2-s2.0-67049098984&partnerID=MN8TOARS.
    10.1021/bm900211j
  44. Pereira, S.P.; Fernandes, M.A.S.; Martins, J.D.; Santos, M.S.; Moreno, A.J.M.; Vicente, J.A.F.; Videira, R.A.; Jurado, A.S.. "Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systems". Toxicology in Vitro 23 8 (2009): 1585-1590. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350731127&partnerID=MN8TOARS.
    10.1016/j.tiv.2009.06.032
  45. Monteiro, J.P.; Videira, R.A.; Matos, M.J.; Dinis, A.M.; Jurado, A.S.. "Non-selective toxicological effects of the insect Juvenile Hormone analogue methoprene. A membrane biophysical approach". Applied Biochemistry and Biotechnology 150 3 (2008): 243-257. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149136593&partnerID=MN8TOARS.
    10.1007/s12010-007-8127-6
  46. Fernandes, M.A.S.; Pereira, S.P.S.; Jurado, A.S.; Custódio, J.B.A.; Santos, M.S.; Moreno, A.J.M.; Duburs, G.; Vicente, J.A.F.. "Comparative effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: Relevance to the length of the alkoxyl chain in positions 3 and 5 of the DHP ring". Chemico-Biological Interactions 173 3 (2008): 195-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-44349090863&partnerID=MN8TOARS.
    10.1016/j.cbi.2008.03.001
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  49. Fernandes, M.A.S.; Jurado, A.S.; Videira, R.A.; Santos, M.S.; Moreno, A.J.M.; Velena, A.; Duburs, G.; Oliveira, C.R.; Vicente, J.A.F.. "Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria". Mitochondrion 5 5 (2005): 341-351. http://www.scopus.com/inward/record.url?eid=2-s2.0-26444543796&partnerID=MN8TOARS.
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  50. Martins, J.D.; Jurado, A.S.; Moreno, A.J.M.; Madeira, V.M.C.. "Comparative study of tributyltin toxicity on two bacteria of the genus Bacillus". Toxicology in Vitro 19 7 (2005): 943-949. http://www.scopus.com/inward/record.url?eid=2-s2.0-27644516005&partnerID=MN8TOARS.
    10.1016/j.tiv.2005.06.019
  51. Monteiro, J.P.; Martins, J.D.; Luxo, P.C.; Jurado, A.S.; Madeira, V.M.C.. "Molecular mechanisms of the metabolite 4-hydroxytamoxifen of the anticancer drug tamoxifen: Use of a model microorganism". Toxicology in Vitro 17 5-6 (2003): 629-634. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242266960&partnerID=MN8TOARS.
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  53. Martins, J.D.; Monteiro, J.P.; Antunes-Madeira, M.C.; Jurado, A.S.; Madeira, V.M.C.. "Use of the microorganism Bacillus stearothermophilus as a model to evaluate toxicity of the lipophilic environmental pollutant endosulfan". Toxicology in Vitro 17 5-6 (2003): 595-601. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242361628&partnerID=MN8TOARS.
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  55. Donato, M.M.; Jurado, A.S.; Antunes-Madeira, M.C.; Madeira, V.M.C.. "Membrane lipid composition of Bacillus stearothermophilus as affected by lipophilic environmental pollutants: An approach to membrane toxicity assessment". Archives of Environmental Contamination and Toxicology 39 2 (2000): 145-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033913854&partnerID=MN8TOARS.
    10.1007/s002440010090
  56. Rosa, S.M.L.J.; Antunes-Madeira, M.C.; Jurado, A.S.; Madeira, V.V.M.C.. "Amiodarone interactions with membrane lipids and with growth of Bacillus stearothermophilus used as a model". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 87 3 (2000): 165-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033864350&partnerID=MN8TOARS.
  57. Luxo, C.; Jurado, A.S.; Madeira, V.M.C.. "Toxicity assessment of tamoxifen by means of a bacterial model". Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology 87 3 (2000): 219-232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033851431&partnerID=MN8TOARS.
    10.1385/ABAB:87:3:219
  58. Rosa, S.M.L.J.; Antunes-Madeira, M.D.C.; Matos, M.J.; Jurado, A.S.; Madeira, V.M.C.. "Lipid composition and dynamics of cell membranes of Bacillus stearothermophilus adapted to amiodarone". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1487 2-3 (2000): 286-295. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034721546&partnerID=MN8TOARS.
    10.1016/S1388-1981(00)00122-0
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Capítulo de livro
  1. Monteiro, J.P.; Jurado, A.S.. "Methoprene". 246-249. 2014.
Livro
  1. Cardoso, A.M.; Guedes, J.R.; Cardoso, A.L.; Morais, C.; Cunha, P.; Viegas, A.T.; Costa, R.; Jurado, A.; Pedroso de Lima, M.C.. Recent Trends in Nanotechnology Toward CNS Diseases: Lipid-Based Nanoparticles and Exosomes for Targeted Therapeutic Delivery. 2016.
    10.1016/bs.irn.2016.05.002
  2. Cardoso, A.M.S.; Silva, S.G.; Luísa Do Vale, M.; Marques, E.F.; Pedroso De Lima, M.C.; Jurado, A.S.. Gene Delivery Mediated by Gemini Surfactants: Structure-Activity Relationships. 2016.
    10.1016/B978-0-323-41532-3.00007-5