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Identificação

Identificação pessoal

Nome completo
Rachela Popovtzer

Nomes de citação

  • Popovtzer, Rachela

Identificadores de autor

Ciência ID
1011-D728-0DD7
ORCID iD
0000-0002-3585-348X
Formação
Grau Classificação
2002 - 2006
Concluído
 Electrical Engineering (Doctor of Philosophy)
Tel Aviv University, Israel
"Electrochemical biochip for electronic detection of biological activity. " (TESE/DISSERTAÇÃO)
1997 - 1999
Concluído
 Biomedical Engineering (Master)
Tel Aviv University, Israel
"Quantitative characterization of bone mineral density using X-ray " (TESE/DISSERTAÇÃO)
1993 - 1996
Concluído
 Physics and Philosophy (Bachelor)
Bar-Ilan University, Israel
Percurso profissional

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/01/01 - Atual Professor Bar-Ilan University Faculty of Engineering, Israel
2018 - Atual Vice Dean of the Faculty of Engineering Bar-Ilan University, Israel
2014 - 2019 Associate Professor Bar-Ilan University Faculty of Engineering, Israel
2015 - 2018 Head of Bioengineering Track Bar-Ilan University Faculty of Engineering, Israel
2008 - 2014 Senior Lecturer Bar-Ilan University Faculty of Engineering, Israel
2006 - 2008 Post Doctorate University of Michigan, Estados Unidos
Produções

Publicações

Artigo em revista
  1. Betzer, Oshra; Barnoy, Eran; Sadan, Tamar; Elbaz, Idan; Braverman, Cara; Liu, Zhuang; Popovtzer, Rachela. "Advances in imaging strategies for in vivo tracking of exosomes". WIREs Nanomedicine and Nanobiotechnology 12 2 (2019): http://dx.doi.org/10.1002/wnan.1594.
    10.1002/wnan.1594
  2. Guo, Shaowei; Perets, Nisim; Betzer, Oshra; Ben-Shaul, Shahar; Sheinin, Anton; Michaelevski, Izhak; Popovtzer, Rachela; Offen, Daniel; Levenberg, Shulamit. "Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury". ACS Nano 13 9 (2019): 10015-10028. http://dx.doi.org/10.1021/acsnano.9b01892.
    10.1021/acsnano.9b01892
  3. Motiei, Menachem; Dreifuss, Tamar; Sadan, Tamar; Omer, Noam; Blumenfeld-Katzir, Tamar; Fragogeorgi, Eirini; Loudos, George; Popovtzer, Rachela; Ben-Eliezer, Noam. "Trimodal Nanoparticle Contrast Agent for CT, MRI and SPECT Imaging: Synthesis and Characterization of Radiolabeled Core/Shell Iron Oxide@Gold Nanoparticles". Chemistry Letters 48 3 (2019): 291-294. http://dx.doi.org/10.1246/cl.180780.
    10.1246/cl.180780
  4. Perets, Nisim; Betzer, Oshra; Shapira, Ronit; Brenstein, Shmuel; Angel, Ariel; Sadan, Tamar; Ashery, Uri; Popovtzer, Rachela; Offen, Daniel. "Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders". Nano Letters 19 6 (2019): 3422-3431. http://dx.doi.org/10.1021/acs.nanolett.8b04148.
    10.1021/acs.nanolett.8b04148
  5. Bier, Ariel; Berenstein, Peter; Kronfeld, Noam; Morgoulis, Daria; Ziv-Av, Amotz; Goldstein, Hodaya; Kazimirsky, Gila; et al. "Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy". Biomaterials 174 (2018): 67-78. http://dx.doi.org/10.1016/j.biomaterials.2018.04.055.
    10.1016/j.biomaterials.2018.04.055
  6. Dreifuss, Tamar; Ben-Gal, Tal-Shachar; Shamalov, Katerina; Weiss, Aryeh; Jacob, Avi; Sadan, Tamar; Motiei, Menachem; Popovtzer, Rachela. "Uptake mechanism of metabolic-targeted gold nanoparticles". Nanomedicine 13 13 (2018): 1535-1549. http://dx.doi.org/10.2217/nnm-2018-0022.
    10.2217/nnm-2018-0022
  7. Sadan, Tamar; Cormode, David P.; Popovtzer, Rachela. "Nanoinformatics Revolutionizes Personalized Cancer Therapy". Trends in Cancer 4 6 (2018): 397-399. http://dx.doi.org/10.1016/j.trecan.2018.04.002.
    10.1016/j.trecan.2018.04.002
  8. Meir, Rinat; Shamalov, Katerina; Sadan, Tamar; Motiei, Menachem; Yaari, Gur; Cohen, Cyrille J.; Popovtzer, Rachela. "Fast Image-Guided Stratification Using Anti-Programmed Death Ligand 1 Gold Nanoparticles for Cancer Immunotherapy". ACS Nano 11 11 (2017): 11127-11134. http://dx.doi.org/10.1021/acsnano.7b05299.
    10.1021/acsnano.7b05299
  9. Betzer, Oshra; Perets, Nisim; Angel, Ariel; Motiei, Menachem; Sadan, Tamar; Yadid, Gal; Offen, Daniel; Popovtzer, Rachela. "In Vivo Neuroimaging of Exosomes Using Gold Nanoparticles". ACS Nano 11 11 (2017): 10883-10893. http://dx.doi.org/10.1021/acsnano.7b04495.
    10.1021/acsnano.7b04495
  10. Meir, Rinat; Popovtzer, Rachela. "Cell tracking using gold nanoparticles and computed tomography imaging". Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 10 2 (2017): e1480. http://dx.doi.org/10.1002/wnan.1480.
    10.1002/wnan.1480
  11. Meir, Rinat; Betzer, Oshra; Motiei, Menachem; Kronfeld, Noam; Brodie, Chaya; Popovtzer, Rachela. "Design principles for noninvasive, longitudinal and quantitative cell tracking with nanoparticle-based CT imaging". Nanomedicine: Nanotechnology, Biology and Medicine 13 2 (2017): 421-429. http://dx.doi.org/10.1016/j.nano.2016.09.013.
    10.1016/j.nano.2016.09.013
  12. Shwartz, Amit; Betzer, Oshra; Kronfeld, Noam; Kazimirsky, Gila; Cazacu, Simona; Finniss, Susan; Lee, Hae Kyung; et al. "Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression". Theranostics 7 10 (2017): 2690-2703. http://dx.doi.org/10.7150/thno.18914.
    10.7150/thno.18914
  13. Hazkani, Inbal; Motiei, Menachem; Betzer, Oshra; Sadan, Tamar; Bragilovski, Dimitri; Lubimov, Leon; Mizrachi, Aviram; et al. "Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma". Theranostics 7 16 (2017): 3962-3971. http://dx.doi.org/10.7150/thno.19615.
    10.7150/thno.19615
  14. Popovtzer, Aron; Mizrachi, Aviram; Motiei, Menachem; Bragilovski, Dimitri; Lubimov, Leon; Levi, Mattan; Hilly, Ohad; Ben-Aharon, Irit; Popovtzer, Rachela. "Actively targeted gold nanoparticles as novel radiosensitizer agents: an in vivo head and neck cancer model". Nanoscale 8 5 (2016): 2678-2685. http://dx.doi.org/10.1039/c5nr07496g.
    10.1039/c5nr07496g
  15. Dreifuss, Tamar; Betzer, Oshra; Shilo, Malka; Popovtzer, Aron; Motiei, Menachem; Popovtzer, Rachela. "A challenge for theranostics: is the optimal particle for therapy also optimal for diagnostics?". Nanoscale 7 37 (2015): 15175-15184. http://dx.doi.org/10.1039/c5nr03119b.
    10.1039/c5nr03119b
  16. Curry, Taeyjuana; Kopelman, Raoul; Shilo, Malka; Popovtzer, Rachela. "Multifunctional theranostic gold nanoparticles for targeted CT imaging and photothermal therapy". Contrast Media & Molecular Imaging 9 1 (2014): 53-61. http://dx.doi.org/10.1002/cmmi.1563.
    10.1002/cmmi.1563
  17. Shilo, Malka; Reuveni, Tobi; Motiei, Menachem; Popovtzer, Rachela. "Nanoparticles as computed tomography contrast agents: current status and future perspectives". Nanomedicine 7 2 (2012): 257-269. http://dx.doi.org/10.2217/nnm.11.190.
    10.2217/nnm.11.190
  18. Peretz, Vital; Motiei, Menachem; Sukenik, Chaim N.; Popovtzer, Rachela. "The Effect of Nanoparticle Size on Cellular Binding Probability". Journal of Atomic, Molecular, and Optical Physics 2012 (2012): 1-7. http://dx.doi.org/10.1155/2012/404536.
    10.1155/2012/404536
  19. Popovtzer, Rachela; Reuveni; Motiei; Romman; Popovtzer. "Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study". International Journal of Nanomedicine (2011): 2859. http://dx.doi.org/10.2147/ijn.s25446.
    10.2147/ijn.s25446
Capítulo de livro
  1. Dreifuss, Tamar; Barnoy, Eran; Motiei, Menachem; Popovtzer, Rachela. "Theranostic Gold Nanoparticles for CT Imaging". In Design and Applications of Nanoparticles in Biomedical Imaging, 403-427. Springer International Publishing, 2016.
    10.1007/978-3-319-42169-8_19
  2. Popovtzer, Rachela. "Nanoparticles in Computed Tomography". In Nanotechnology in Modern Medical Imaging and Interventions. Nova, 2013.

Propriedade Intelectual

Patente
  1. Popovtzer, Rachela. 2019. "Glucose Conjugated Gold Nanoparticle".
  2. Popovtzer, Rachela. 2019. "Delta Receptor Agonist Pepetides and Use Thereof".
  3. Popovtzer, Rachela. 2013. "Immuno-targeted plasmonic nanoparticles for spectroscopic detection of colon cancer".
Distinções

Prémio

2017 Taubenblatt Prize for Excellence in Medical Research
Taubenblatt Foundation, Israel
2010 Crown Foundation Award for Returning Scientist
Crown Foundation , Estados Unidos
2008 Novel and Innovative Idea for Cancer Research Award
University of Michigan, Estados Unidos
2005 Intel Prize USA for Outstanding PhD Thesis
Intel, Estados Unidos
2005 Environment and Living foundation Prize for outstanding research work in the field of Nano-Bio-Technology.
Universität Konstanz, Alemanha

Outra distinção

2015 Kavli Frontiers of Science Fellow, National Academy of Sciences, Kavli Foundation
The Kavli Foundation, Estados Unidos