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Maria João Rodrigues Pereira. Publicou 35 artigos em revistas especializadas.
Identificação

Identificação pessoal

Nome completo
Maria João Rodrigues Pereira

Nomes de citação

  • Pereira, Maria J

Identificadores de autor

Ciência ID
1513-EB2F-0D7F
ORCID iD
0000-0001-5498-3899

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Sueco Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2008/06/01 - 2012/11/16
Concluído
 Medical Sciences (Doktor (PhD))
Göteborgs Universitet, Suécia
"Effects of immunosuppressive agents on adipose tissue metabolism " (TESE/DISSERTAÇÃO)
1999/10/01 - 2003/12/15
Concluído
 Biochemistry (Licenciatura)
Universidade do Algarve - Campus de Gambelas, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/04/01 - Atual Investigador (Investigação) Uppsala universitet Institutionen för medicinska vetenskaper, Suécia
2013/04/01 - 2020/03/31 Pós-doutorado (Investigação) Uppsala universitet Institutionen för medicinska vetenskaper, Suécia
2012/12/01 - 2013/03/31 Pós-doutorado (Investigação) Göteborgs Universitet, Suécia

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/04/01 - Atual Professor Associado (Docente Universitário) Uppsala Universitet, Suécia

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2003/04/01 - 2008/04/30 Assessor Superior (Técnico Superior de Saúde - Laboratório) António Mergulhão SA, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2002/01/01 - 2003/09/30 Managing partner Microsolution, Lda, Portugal
Produções

Publicações

Artigo em revista
  1. Pedro Barbosa; Aryane Pinho; André Lázaro; Diogo Paula; José G. Tralhão; Artur Paiva; Maria J. Pereira; Eugenia Carvalho; Paula Laranjeira. "Bariatric Surgery Induces Alterations in the Immune Profile of Peripheral Blood T Cells". Biomolecules (2024): https://doi.org/10.3390/biom14020219.
    10.3390/biom14020219
  2. Martin H Lundqvist; Maria J Pereira; Kristina Almby; Susanne Hetty; Jan W Eriksson. "Regulation of the Cortisol Axis, Glucagon, and Growth Hormone by Glucose Is Altered in Prediabetes and Type 2 Diabetes". The Journal of Clinical Endocrinology & Metabolism (2024): https://doi.org/10.1210/clinem/dgad549.
    10.1210/clinem/dgad549
  3. Pedro Barbosa; Aryane Pinho; André Lázaro; Daniela Rosendo-Silva; Diogo Paula; José Campos; José G. Tralhão; et al. "CD8+ Treg cells play a role in the obesity-associated insulin resistance". Life Sciences (2024): http://dx.doi.org/10.1016/j.lfs.2023.122306.
    10.1016/j.lfs.2023.122306
  4. Patricia O. Benedet; Nooshin S. Safikhan; Maria J. Pereira; Bryan M. Lum; José Diego Botezelli; Cheng-Hsiang Kuo; Hua-Lin Wu; et al. "CD248 promotes insulin resistance by binding to the insulin receptor and dampening its insulin-induced autophosphorylation". eBioMedicine (2024): http://dx.doi.org/10.1016/j.ebiom.2023.104906.
    10.1016/j.ebiom.2023.104906
  5. Susanne Hetty; Milica Vranic; Prasad G Kamble; Martin H Lundqvist; Maria J Pereira; Jan W Eriksson. "CABLES1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism". Adipocyte (2023): http://dx.doi.org/10.1080/21623945.2023.2242997.
    10.1080/21623945.2023.2242997
  6. Fozia Ahmed; Milica Vranic; Susanne Hetty; Argyri Mathioudaki; Vagia Patsoukaki; Giovanni Fanni; Maria J Pereira; Jan W Eriksson. "Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women". Endocrinology (2023): https://doi.org/10.1210/endocr/bqad172.
    10.1210/endocr/bqad172
  7. Milica Vranic; Fozia Ahmed; Robin Kristófi; Susanne Hetty; Dariush Mokhtari; Maria K. Svensson; Jan W. Eriksson; Maria J. Pereira. "Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D". Endocrine (2023): https://doi.org/10.1007/s12020-023-03525-1.
    10.1007/s12020-023-03525-1
  8. Martin H. Lundqvist; Maria J. Pereira; Jan W. Eriksson. "Glucose-dependent inflammatory responses in obese compared to lean individuals". Endocrine (2023): https://doi.org/10.1007/s12020-023-03433-4.
    10.1007/s12020-023-03433-4
  9. Milica Vranic; Fozia Ahmed; Susanne Hetty; Assel Sarsenbayeva; Vitor Ferreira; Giovanni Fanni; Ángela M. Valverde; Jan W. Eriksson; Maria J. Pereira. "Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation". Molecular and Cellular Endocrinology (2023): https://doi.org/10.1016/j.mce.2022.111828.
    10.1016/j.mce.2022.111828
  10. Giovanni Fanni; Jan W. Eriksson; Maria J. Pereira. "Several Metabolite Families Display Inflexibility during Glucose Challenge in Patients with Type 2 Diabetes: An Untargeted Metabolomics Study". Metabolites (2023): https://doi.org/10.3390/metabo13010131.
    10.3390/metabo13010131
  11. Maria J Pereira; Ayesha Azim; Susanne Hetty; Bipasha Nandi Jui; Joel Kullberg; Martin H Lundqvist; Jan W Eriksson. "Interleukin-33 inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes". Cytokine (2023): https://doi.org/10.1016/j.cyto.2022.156080.
    10.1016/j.cyto.2022.156080
  12. Fozia Ahmed; Susanne Hetty; Milica Vranic; Giovanni Fanni; Joel Kullberg; Maria João Pereira; Jan Eriksson. "ESR2 expression in subcutaneous adipose tissue is related to body fat distribution in women, and knockdown impairs preadipocyte differentiation". Adipocyte (2022): http://dx.doi.org/10.1080/21623945.2022.2102116.
    10.1080/21623945.2022.2102116
  13. Giovanni Fanni; Petros Katsogiannos; Bipasha Nandi Jui; Magnus Sundbom; Susanne Hetty; Maria J Pereira; Jan W Eriksson. "Response of multiple hormones to glucose and arginine challenge in T2DM after gastric bypass". Endocrine Connections (2022): https://doi.org/10.1530/EC-22-0172.
    10.1530/EC-22-0172
  14. Bipasha Nandi Jui; Assel Sarsenbayeva; Henning Jernow; Susanne Hetty; Maria J Pereira. "Evaluation of RNA Isolation Methods in Human Adipose Tissue". Laboratory Medicine (2022): https://doi.org/10.1093/labmed/lmab126.
    10.1093/labmed/lmab126
  15. Ahmed, Fozia; Kamble, Prasad G; Hetty, Susanne; Fanni, Giovanni; Vranic, Milica; Sarsenbayeva, Assel; Kristófi, Robin; et al. "Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women". The Journal of Clinical Endocrinology & Metabolism 107 5 (2022): e1879-e1889. http://dx.doi.org/10.1210/clinem/dgac042.
    10.1210/clinem/dgac042
  16. ARYANE C.O. PINHO; ANA BURGEIRO; MARIA JOÃO PEREIRA; EUGENIA CARVALHO. "Drug-induced metabolic alterations in adipose tissue - with an emphasis in epicardial adipose tissue". Anais da Academia Brasileira de Ciências 94 1 (2022): https://doi.org/10.1590/0001-3765202220201819.
    10.1590/0001-3765202220201819
  17. MARIA J Pereira; MILICA VRANIC; PRASAD G KAMBLE; HENNING JERNOW; ROBIN KRISTÓFI; EMA HOLBIKOVA; STANKO SKRTIC; et al. "CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?". Translational Research (2021): https://doi.org/10.1016/j.trsl.2021.12.003.
    10.1016/j.trsl.2021.12.003
  18. Torres, Alejandra N.; Tavares, Ludgero; Pereira, Maria J.; Eriksson, Jan W.; Jones, John G.. "Positional and compositional analysis of saturated, monounsaturated, and polyunsaturated fatty acids in human adipose tissue triglyceride by 13C nuclear magnetic resonance". NMR in Biomedicine 36 4 (2021): http://dx.doi.org/10.1002/nbm.4632.
    10.1002/nbm.4632
  19. Sarsenbayeva, Assel; Jui, Bipasha Nandi; Fanni, Giovanni; Barbosa, Pedro; Ahmed, Fozia; Kristófi, Robin; Cen, Jing; et al. "Impaired HMG-CoA Reductase Activity Caused by Genetic Variants or Statin Exposure: Impact on Human Adipose Tissue, ß-Cells and Metabolome". Metabolites 11 9 (2021): 574. http://dx.doi.org/10.3390/metabo11090574.
    10.3390/metabo11090574
  20. Priya Dipta; Assel Sarsenbayeva; Miriam Shmuel; Francesca Forno; Jan W. Eriksson; Maria J. Pereira; Xesús M. Abalo; et al. "Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes". Comprehensive Psychoneuroendocrinology 7 (2021): 100073-100073. https://doi.org/10.1016/j.cpnec.2021.100073.
    10.1016/j.cpnec.2021.100073
  21. Almby, Kristina E; Katsogiannos, Petros; Pereira, Maria J; Karlsson, F Anders; Sundbom, Magnus; Wiklund, Urban; Kamble, Prasad G; Eriksson, Jan W. "Time Course of Metabolic, Neuroendocrine, and Adipose Effects During 2 Years of Follow-up After Gastric Bypass in Patients With Type 2 Diabetes". The Journal of Clinical Endocrinology & Metabolism 106 10 (2021): e4049-e4061. http://dx.doi.org/10.1210/clinem/dgab398.
    10.1210/clinem/dgab398
  22. Eriksson, Jan W; Visvanathar, Robin; Kullberg, Joel; Strand, Robin; Skrtic, Stanko; Ekström, Simon; Lubberink, Mark; et al. "Tissue-specific glucose partitioning and fat content in prediabetes and type 2 diabetes: whole-body PET/MRI during hyperinsulinemia". European Journal of Endocrinology 184 6 (2021): 879-889. http://dx.doi.org/10.1530/eje-20-1359.
    10.1530/eje-20-1359
  23. Pereira, Maria J.; Andersson-Assarsson, Johanna C.; Jacobson, Peter; Kamble, Prasad; Taube, Magdalena; Sjöholm, Kajsa; Carlsson, Lena M. S.; Svensson, Per-Arne. "Human adipose tissue gene expression of solute carrier family 19 member 3 (SLC19A3); relation to obesity and weight-loss". Obesity Science & Practice 8 1 (2021): 21-31. http://dx.doi.org/10.1002/osp4.541.
    10.1002/osp4.541
  24. Almby, Kristina E.; Lundqvist, Martin H.; Abrahamsson, Niclas; Kvernby, Sofia; Fahlström, Markus; Pereira, Maria J.; Gingnell, Malin; et al. "Effects of Gastric Bypass Surgery on the Brain: Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity, and Cognitive Function During Normo- and Hypoglycemia". Diabetes 70 6 (2021): 1265-1277. http://dx.doi.org/10.2337/db20-1172.
    10.2337/db20-1172
  25. Katsogiannos, Petros; Kamble, Prasad G.; Pereira, Maria J.; Sundbom, Magnus; Carlsson, Per-Ola; Eriksson, Jan W.; Espes, Daniel. "Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes". Obesity 29 3 (2021): 535-542. http://dx.doi.org/10.1002/oby.23093.
    10.1002/oby.23093
  26. Fozia Ahmed; Assel Sarsenbayeva; Petros Katsogiannos; Céline Aguer; Maria J Pereira. "The effects of bisphenol A and bisphenol S on adipokine expression and glucose metabolism in human adipose tissue". Toxicology 445 (2020): 152600-152600. https://doi.org/10.1016/j.tox.2020.152600.
    10.1016/j.tox.2020.152600
  27. Sarsenbayeva, Assel; Dipta, Priya; Lundqvist, Martin; Almby, Kristina E.; Tirosh, Boaz; Di Nunzio, Giada; Eriksson, Jan W.; Pereira, Maria J.. "Human macrophages stimulate expression of inflammatory mediators in adipocytes; effects of second-generation antipsychotics and glucocorticoids on cellular cross-talk". Psychoneuroendocrinology 125 (2020): 105071. http://dx.doi.org/10.1016/j.psyneuen.2020.105071.
    10.1016/j.psyneuen.2020.105071
  28. Martin H. Lundqvist; Kristina Almby; Urban Wiklund; Niclas Abrahamsson; Prasad G. Kamble; Maria J. Pereira; Jan W. Eriksson. "Altered hormonal and autonomic nerve responses to hypo- and hyperglycaemia are found in overweight and insulin-resistant individuals and may contribute to the development of type 2 diabetes". Diabetologia (2020): https://doi.org/10.1007/s00125-020-05332-z.
    10.1007/s00125-020-05332-z
  29. Kamble, Prasad G.; Hetty, Susanne; Vranic, Milica; Almby, Kristina; Castillejo-López, Casimiro; Abalo, Xesús M.; Pereira, Maria J.; Eriksson, Jan W.. "Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-67293-y.
    10.1038/s41598-020-67293-y
  30. Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J.; Cavalli, Marco; Pan, Gang; Kumar, Chanchal; Skrtic, Stanko; et al. "Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-64524-0.
    10.1038/s41598-020-64524-0
  31. Sjöholm, Åke; Pereira, Maria João; Nilsson, Thomas; Linde, Torbjörn; Katsogiannos, Petros; Saaf, Jan; Eriksson, Jan W. "Type B insulin resistance syndrome in a patient with type 1 diabetes". Endocrinology, Diabetes & Metabolism Case Reports 2020 (2020): http://dx.doi.org/10.1530/edm-19-0157.
    10.1530/edm-19-0157
  32. Guglielmo, P.; Ekström, S.; Strand, R.; Visvanathar, R.; Malmberg, F.; Johansson, E.; Pereira, M. J.; et al. "Validation of automated whole-body analysis of metabolic and morphological parameters from an integrated FDG-PET/MRI acquisition". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-62353-9.
    10.1038/s41598-020-62353-9
  33. Maria J. Pereira; Ketan Thombare; Assel Sarsenbayeva; Prasad G. Kamble; Kristina Almby; Martin Lundqvist; Jan W. Eriksson. "Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes". Molecular and Cellular Endocrinology 503 (2020): 110696-110696. https://doi.org/10.1016/j.mce.2019.110696.
    10.1016/j.mce.2019.110696
  34. Katsogiannos, Petros; Kamble, Prasad G.; Wiklund, Urban; Sundbom, Magnus; Espes, Daniel; Hammar, Ulf; Karlsson, F. Anders; Pereira, Maria J.; Eriksson, Jan W.. "Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery". Endocrine 67 2 (2020): 344-353. http://dx.doi.org/10.1007/s12020-020-02203-w.
    10.1007/s12020-020-02203-w
  35. Klev Diamanti; Marco Cavalli; Gang Pan; Maria J. Pereira; Chanchal Kumar; Stanko Skrtic; Manfred Grabherr; et al. "Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-45906-5.
    10.1038/s41598-019-45906-5
  36. Sarsenbayeva, Assel; Marques-Santos, Cátia M.; Thombare, Ketan; Di Nunzio, Giada; Almby, Kristina E.; Lundqvist, Martin; Eriksson, Jan W.; Pereira, Maria J.. "Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism". Psychoneuroendocrinology 110 (2019): 104445. http://dx.doi.org/10.1016/j.psyneuen.2019.104445.
    10.1016/j.psyneuen.2019.104445
  37. Klev Diamanti; Marco Cavalli; Gang Pan; Maria J. Pereira; Chanchal Kumar; Stanko Skrtic; Manfred Grabherr; et al. "Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-54423-4.
    10.1038/s41598-019-54423-4
  38. Petros Katsogiannos; Prasad G Kamble; Gretha J Boersma; F Anders Karlsson; Per Lundkvist; Magnus Sundbom; Maria J Pereira; Jan W Eriksson. "Early Changes in Adipose Tissue Morphology, Gene Expression, and Metabolism After RYGB in Patients With Obesity and T2D". The Journal of Clinical Endocrinology & Metabolism (2019): https://doi.org/10.1210/jc.2018-02165.
    10.1210/jc.2018-02165
  39. Prasad G. Kamble; Maria J. Pereira; Kristina Almby; Jan W. Eriksson. "Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor a and ß in insulin resistance?". Molecular and Cellular Endocrinology (2019): https://doi.org/10.1016/j.mce.2019.04.002.
    10.1016/j.mce.2019.04.002
  40. Lundkvist P; Pereira MJ; Kamble PG; Katsogiannos P; Langkilde AM; Esterline R; Johnsson E; Eriksson JW. "Glucagon Levels During Short-Term SGLT2 Inhibition Are Largely Regulated by Glucose Changes in Patients With Type 2 Diabetes.". The Journal of clinical endocrinology and metabolism (2019): http://europepmc.org/abstract/med/30137410.
    10.1210/jc.2018-00969
  41. Pereira MJ; Eriksson JW. "Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity.". Drugs (2019): http://europepmc.org/abstract/med/30701480.
    10.1007/s40265-019-1057-0
  42. Ana Catarina R. G. Fonseca; Eugénia Carvalho; Jan W. Eriksson; Maria J. Pereira. "Calcineurin is an important factor involved in glucose uptake in human adipocytes". Molecular and Cellular Biochemistry 445 1-2 (2018): 157-168. https://doi.org/10.1007/s11010-017-3261-0.
    10.1007/s11010-017-3261-0
  43. Boersma GJ; Johansson E; Pereira MJ; Heurling K; Skrtic S; Lau J; Katsogiannos P; et al. "Altered Glucose Uptake in Muscle, Visceral Adipose Tissue, and Brain Predict Whole-Body Insulin Resistance and may Contribute to the Development of Type 2 Diabetes: A Combined PET/MR Study.". Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme (2018): http://europepmc.org/abstract/med/30669164.
    10.1055/a-0831-3620
  44. Kamble PG; Pereira MJ; Gustafsson S; Lundkvist P; Castillejo-López C; Fall T; Ingelsson E; Eriksson JW. "Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.". Adipocyte (2018): http://europepmc.org/abstract/med/30064293.
    10.1080/21623945.2018.1503030
  45. Sidibeh CO; Pereira MJ; Abalo XM; J Boersma G; Skrtic S; Lundkvist P; Katsogiannos P; et al. "FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes.". Endocrine (2018): http://europepmc.org/abstract/med/30032404.
    10.1007/s12020-018-1674-5
  46. Pereira MJ; Lundkvist P; Kamble PG; Lau J; Martins JG; Sjöström CD; Schnecke V; et al. "A Randomized Controlled Trial of Dapagliflozin Plus Once-Weekly Exenatide Versus Placebo in Individuals with Obesity and Without Diabetes: Metabolic Effects and Markers Associated with Bodyweight Loss.". Diabetes therapy : research, treatment and education of diabetes and related disorders (2018): http://europepmc.org/abstract/med/29949016.
    10.1007/s13300-018-0449-6
  47. Hansson SF; Zhou AX; Vachet P; Eriksson JW; Pereira MJ; Skrtic S; Jongsma Wallin H; et al. "Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.". PloS one (2018): http://europepmc.org/abstract/med/29702679.
    10.1371/journal.pone.0196601
  48. Kamble PG; Gustafsson S; Pereira MJ; Lundkvist P; Cook N; Lind L; Franks PW; et al. "Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers.". Upsala journal of medical sciences (2017): http://europepmc.org/abstract/med/29303622.
    10.1080/03009734.2017.1405127
  49. Lundkvist P; Pereira MJ; Katsogiannos P; Sjöström CD; Johnsson E; Eriksson JW. "Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: Sustained reductions in body weight, glycaemia and blood pressure over 1¿year.". Diabetes, obesity & metabolism (2017): http://europepmc.org/abstract/med/28345814.
    10.1111/dom.12954
  50. Lundkvist P; Sjöström CD; Amini S; Pereira MJ; Johnsson E; Eriksson JW. "Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes.". (2017): http://europepmc.org/abstract/med/27550386.
    10.1111/dom.12779
  51. Pereira MJ; Skrtic S; Katsogiannos P; Abrahamsson N; Sidibeh CO; Dahgam S; Månsson M; et al. "Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors.". (2016): http://europepmc.org/abstract/med/27832864.
    10.1016/j.metabol.2016.09.008
  52. Sidibeh CO; Pereira MJ; Lau Börjesson J; Kamble PG; Skrtic S; Katsogiannos P; Sundbom M; Svensson MK; Eriksson JW. "Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance.". (2016): http://europepmc.org/abstract/med/27858284.
  53. Fryk E; Sundelin JP; Strindberg L; Pereira MJ; Federici M; Marx N; Nyström FH; et al. "Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients.". (2016): http://europepmc.org/abstract/med/27282870.
    10.1016/j.metabol.2016.04.003
  54. Kamble PG; Pereira MJ; Sidibeh CO; Amini S; Sundbom M; Börjesson JL; Eriksson JW. "Lipocalin 2 produces insulin resistance and can be upregulated by glucocorticoids in human adipose tissue.". (2016): http://europepmc.org/abstract/med/26973291.
    10.1016/j.mce.2016.03.011
  55. Taube M; Andersson-Assarsson JC; Lindberg K; Pereira MJ; Gäbel M; Svensson MK; Eriksson JW; Svensson PA. "Evaluation of reference genes for gene expression studies in human brown adipose tissue.". (2015): http://europepmc.org/abstract/med/26451284.
    10.1080/21623945.2015.1039884
  56. Pereira MJ; Palming J; Svensson MK; Rizell M; Dalenbäck J; Hammar M; Fall T; et al. "FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance.". (2014): http://europepmc.org/abstract/med/24997500.
    10.1016/j.metabol.2014.05.015
  57. Lopes PC; Fuhrmann A; Carvalho F; Sereno J; Santos MR; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment.". (2014): http://europepmc.org/abstract/med/24960264.
    10.1016/j.bcp.2014.06.014
  58. Pereira MJ; Eriksson JW; Svensson MK. "A case report of improved metabolic control after conversion from everolimus to cyclosporin a: role of adipose tissue mechanisms?". (2014): http://europepmc.org/abstract/med/25242791.
    10.1016/j.transproceed.2014.02.018
  59. Svensson PA; Lindberg K; Hoffmann JM; Taube M; Pereira MJ; Mohsen-Kanson T; Hafner AL; et al. "Characterization of brown adipose tissue in the human perirenal depot.". (2014): http://europepmc.org/abstract/med/24753268.
    10.1002/oby.20765
  60. Pereira MJ; Palming J; Rizell M; Aureliano M; Carvalho E; Svensson MK; Eriksson JW. "Cyclosporine A and tacrolimus reduce the amount of GLUT4 at the cell-surface in human adipocytes: increased endocytosis as a potential mechanism for the diabetogenic effects of immunosuppressive agents.". (2014): http://europepmc.org/abstract/med/25004245.
    10.1210/jc.2014-1266
  61. Lopes PC; Fuhrmann A; Sereno J; Espinoza DO; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats.". (2014): http://europepmc.org/abstract/med/24656168.
    10.1016/j.metabol.2014.02.004
  62. Fuhrmann A; Lopes P; Sereno J; Pedro J; Espinoza DO; Pereira MJ; Reis F; Eriksson JW; Carvalho E. "Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model.". (2014): http://europepmc.org/abstract/med/24462915.
    10.1016/j.bcp.2014.01.020
  63. DeSchoolmeester J; Palming J; Persson T; Pereira MJ; Wallerstedt E; Brown H; Gill D; et al. "Differences between men and women in the regulation of adipose 11ß-HSD1 and in its association with adiposity and insulin resistance.". (2013): http://europepmc.org/abstract/med/23701286.
    10.1111/dom.12137
  64. Lopes P; Fuhrmann A; Sereno J; Pereira MJ; Nunes P; Pedro J; Melão A; Reis F; Carvalho E. "Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model.". (2013): http://europepmc.org/abstract/med/23622647.
    10.1016/j.transproceed.2013.02.009
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Outros

Outra produção
  1. Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes and normal tissues. 2021. Klev Diamanti; Marco Cavalli; Maria J. Pereira; Gang Pan; Casimiro Castillejo-Lopez; Chanchal Kumar; Filip Mundt; et al. https://doi.org/10.1101/2021.05.09.443296.
    10.1101/2021.05.09.443296
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/01 Glucocorticoid new targets in adipose tissue Sociedade Portuguesa da Bioquímica (SPB) WCB 2024: "Neurological, cardiovascular and metabolic diseases"
2023/06 Subcutaneous adipose tissue dopamine receptor D2 expression is increased in prediabetes and type 2 diabetes European Diabetes Association
(Alemanha)
2023/06 Cables1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism European Diabetes Association
2022/06 Interleukin-33 (IL33) inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes European Diabetes Association
2022/02/10 Glucocorticoids and adipocyte metabolism: old hormones, new targets 4th Swedish Diabetes Summit
2019 Glucagon Effects In Adipose Tissue EASD-EGIR, Faculdade de Ciências Médicas, Lisboa, Portugal
2019 Drug-induced diabetes IMV seminar at Uppsala University
2016 Alterations in Adipose Tissue Lipid Storage but Not Lipolysis Contribute to Elevated Levels of Free Fatty acids in Type 2 Diabetes American Diabetes Association
(New Orleans, Estados Unidos)
2014 How can immunosuppressive treatments cause diabetes? IMV seminar at Uppsala University
2011 Immunosuppressive agents induce alterations in human subcutaneous adipose tissue gene expression and glucose and lipid metabolism EASD 2011, Lisbon, Portugal
2011 Immunosuppressive therapy may promote development of diabetes and dyslipidemia via alterations in adipose tissue metabolism ADA 2011, San Diego, USA
2008 Relationship between serum lipoprotein ratios and Insulin Resistance 3º Workshop of Clinical Biochemistry, 2008, Porto, Portugal

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/09 - Atual Brain cross-talk to periphery
Coorientador
Uppsala Universitet, Suécia
2023/09 - Atual Adipose tissue neuroendocrine pathways in the development and reversal of obesity and type 2 diabetes
Orientador
Uppsala Universitet, Suécia
2021/05 - Atual Impact of bariatric surgery in neuroendocrine crosstalk controlling glucose homeostasis
Coorientador
Uppsala Universitet, Suécia
2020/11 - Atual Neuroendocrine regulation of estrogen and insulin action in human adipose tissue: implications for type 2 diabetes development
Coorientador
Uppsala Universitet, Suécia
2020 - Atual CD20+ T Cells as a biomarker of inflammatory status and a promising target against cardiac rejection in heart transplanted patients
Coorientador
2019/05/01 - Atual Effects of the antipsychotic drugs on the regulation of human adipose tissue metabolism
Orientador
 Medical Sciences (Doutoramento)
Uppsala Universitet, Suécia
2017/10/01 - Atual Systemic and adipose tissue inflammation – impact for metabolic side effects of antipsychotic drugs
Coorientador
 Medical Sciences (Doutoramento)
Uppsala Universitet, Suécia
2024/01 - 2024/06 Metabolic Impacts of Aromatase and Estrogen Receptors in Male Obesity
Orientador
Uppsala Universitet, Suécia
2023/09 - 2024/06 Adipose tissue fibrosis and metabolic dysregulation – role of collagen VI
Orientador
2023/01 - 2023/06 Role of fibrosis in adipose tissue glucose metabolism – a link with type 2 diabetes?
Orientador
2022/01 - 2022/06 Perirenal fat depots- Characterisation of adipocyte size, glucose uptake, and gene expression
Orientador
2021/08 - 2022/01 Characterization of adipocyte size and glucose uptake in adipose tissue with focus on perirenal adipose tissue
Orientador
Uppsala Universitet, Suécia
2017/10/01 - 2021/10/30 Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?
Coorientador
Uppsala Universitet, Suécia
2021/01 - 2021/06 Effects of LDL-lowering mechanisms on adipocyte function
Orientador
Uppsala Universitet, Suécia
2021/01 - 2021/06 Estrogen functions in the adipocytes, a friend or a foe? : A pilot study
Orientador
Uppsala Universitet, Suécia
2021/01 - 2021/06 Impact of cell cycle regulators CABLES1 and CDKN2C in adipocyte function
Orientador
Uppsala Universitet, Suécia
2019 - 2019 IL-33 Expression in Subcutaneous Adipose Tissue is Associated with Insulin Resistance and Inhibits Glucose Uptake in Human Adipocytes
Orientador
 Biomedicine (Mestrado)
Uppsala Universitet, Suécia
2019 - 2019 Metabolic effects of BPA/BPS in adipose tissue
Orientador
Uppsala Universitet, Suécia
2019 - 2019 CDKN2C expression in adipose tissue
Orientador
Uppsala Universitet, Suécia
2016 - 2019 Metabolic and endocrine effects of SGLT2 inhibition
Coorientador
 Medical Sciences (Doutoramento)
Uppsala Universitet, Suécia
2013 - 2018 Novel mechanisms of glucocorticoid-induced insulin resistance in human adipose tissue
Coorientador
 Medical Sciences (Doutoramento)
Uppsala Universitet, Suécia
2013 - 2018 Role of nuclear receptors in the regulation of human adipose tissue metabolism
Coorientador
 Medical Sciences (Doutoramento)
Uppsala Universitet, Suécia
2016 - 2017 Effects of calcineurin inhibitors in adipocyte metabolism
Orientador
Uppsala Universitet, Suécia

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019 - Atual Annual organization of the Research Track Day in Metabolism at the Uppsala University (2019)
Simpósio (Presidente da Comissão Organizadora)

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2023 - Atual Examining committee’s: Thesis defense: Sarah Reid (2023 Uppsala University); João Vieira (2024 Lund University) Licenciate: Ben Tzu-Pin Tseng (2023 Karolinska Institute)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019 - Atual Diabetes (Master Universitario) Uppsala Universitet, Suécia
2019 - Atual Introduction to pre-clinical research, 2 weeks course Introduction to pre-clinical research (Doktor (PhD)) Uppsala Universitet, Suécia
2019 - Atual Introduction to Pre-Clinical Methods (Postgraduate Certificate) Uppsala Universitet, Suécia
2019 - 2019 Academic Teaching course

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2023/06 - Atual Assessment and Conflict Management Committee Board – PAS GRAS consortium
Membro
2019 - Atual Research Track Metabolism leader at the Institute Medical Sciences
Coordenador
 Uppsala Universitet, Suécia
Distinções

Prémio

2018 Uppsala University Young Research Award
Uppsala Universitet, Suécia
2016 Uppsala University Young Research Award
Uppsala Universitet, Suécia