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Marta Carvalho is Principal Investigator of the project "DentalBioMatrix - Exploiting the power of decellularized extracellular matrix to fabricate hierarchical biomimetic scaffolds to regenerate functional periodontal tissues" (PTDC/BTM-MAT/3538/2020, Fundação para Ciência e Tecnologia, FCT). She completed her PhD in Bioengineering in December 2018 at Instituto Superior Técnico (University of Lisbon) with collaboration with Rensselaer Polytechnic Institute (RPI/USA), followed by a post-doc project in Stem Cell Engineering Research Group (SCERG)/Institute of Bioengineering and Biosciences (iBB) in collaboration with Bionet. She has a Master Degree in Biomedical Engineering and was a visiting scholar at Politecnico di Milano (Italy). Marta also gained industry experience by working at Cell2B as a scientist on the scope of development cell therapies for graft-versus-host disease, acquiring skills in R&D, quality control, project management and GMP. Currently, she is a research associate at iBB and has been working in a multidisciplinary project involving different areas such as Tissue Engineering, Regenerative Medicine, Cell Biology and Biomaterials. Her PhD project was developed at Rensselaer Polytechnic Institute under the supervision of Prof. Deepak Vashishth (RPI) and Prof. Cláudia Lobato da Silva (SCERG), focusing on developing biomimetic 3-D matrices for bone tissue engineering, by exploiting the properties of extracellular matrix. She has 16 publications in top-referred international journals, 1 patent, 2 book chapters and 35 conference communications. Marta has participated as lecturer in some courses and was assistant lab supervisor and mentor of MSc and undergraduate students. She has participated in several international conferences in the field and her work has been recognized by the scientific committee, resulting in a student scientist award and a poster presentation prize. She has been invited to review several papers for international journals in the field and has acted as principal examiner in MSc theses (>10). She is actively involved in supervision activities of MSc and BSc students. Recently, Marta led a team of engineers and clinicians in an accelerator program (Lab2Market, Everis), where she received specialized training in business model and go-to-market strategies and pitched her technology to investors and potential customers. Marta has been collaborating with PreScouter as a medical writer to create a shared vision of how science research profits all of us. Currently, her main research interests are focused in the development of anti-aging bioengineering strategies to regenerate tissues by exploiting the power of decellularized extracellular matrix.
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Identificação

Identificação pessoal

Nome completo
Marta Monteiro Silva Carvalho

Nomes de citação

  • Carvalho, Marta S.
  • Carvalho, Marta

Identificadores de autor

Ciência ID
181D-2482-4BE7
ORCID iD
0000-0003-1026-1995
Google Scholar ID
https://scholar.google.com/citations?user=bxdjaBsAAAAJ&hl=en

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais
  • Ciências da Engenharia e Tecnologias - Outras Ciências da Engenharia e Tecnologias
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Italiano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Francês Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2014/04/01 - 2018/12/04
Concluído
 Bioengineering (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Rensselaer Polytechnic Institute, Estados Unidos
"Stem cell-mediated bone formation on biomimetic 3-D matrices" (TESE/DISSERTAÇÃO)
 Approved with Distinction
2015/12/01
Concluído
 Responsible Conduct of Research - CITI Program (Outros)
Rensselaer Polytechnic Institute, Estados Unidos
2015/10/01
Concluído
 Human Subjects Research - CITI Program (Outros)
Rensselaer Polytechnic Institute, Estados Unidos
2015/06/20
Concluído
 Conflicts of Interest- CITI Program (Outros)
Rensselaer Polytechnic Institute, Estados Unidos
2015/06/20
Concluído
 IACUC: Animal Care and Use - CITI Program (Outros)
Rensselaer Polytechnic Institute, Estados Unidos
2014/05/09
Concluído
 R Programming, on Coursera (Outros)
Johns Hopkins University - Washington DC Center, Estados Unidos
2014/02/12
Concluído
 Fundamentals of Clinical Trials, on edX (Outros)
Harvard University Division of Medical Sciences, Estados Unidos
2013/02/10
Concluído
 Drugs and the Brain, on Coursera (Outros)
California Institute of Technology, Estados Unidos
2007/09/20 - 2012/12/03
Concluído
 Biomedical Engineering (Mestrado integrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Isolation and ex-vivo expansion of endothelial progenitor cells from the umbilical cord blood" (TESE/DISSERTAÇÃO)
 17/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/04/01 - Atual Investigador Contratado (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2019/01/01 - 2019/04/01 Pós-doutorado (Investigação) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2015/01/01 - 2018/06/15 Investigador visitante (Investigação) Rensselaer Polytechnic Institute, Estados Unidos
Center for Biotechnology and Interdisciplinary Studies, Estados Unidos

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/04/01 - 2018/12/04 PhD student Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/10/15 - 2013/12/31 Junior Scientist Cell2B, Portugal
Projetos

Bolsa

Designação Financiadores
2021 - Atual High-resolution 3D printing combined with biomimetic bioinks for the in vitro fabrication of vascularized bone: bridging the gap towards functional regeneration
PARSUK
Investigador
PARSUK
2019/01/01 - 2019/03/31 BIONET
180100921101
Bolseiro de Pós-Doutoramento
Concluído
2014/04/01 - 2018/12/04 PhD Scholarship: "Stem cell-mediated bone formation on biomimetic 3-D matrices"
PD/BD/52478/2014
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2022 - Atual InSilico4OCReg - In silico models guiding in vitro biophysical stimulation of biomimetic hierarchical scaffolds: a computational modelling approach towards functional osteochondral regeneration
PTDC/EME-SIS/0838/2021
Investigador
Instituto de Biotecnologia e Bioengenharia, Portugal

Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
Fundação para a Ciência e a Tecnologia
2022 - Atual BioMaterARISES - Biomaterials for the assemblage of regenerative-inspired scaffolds for the electrical stimulation of spinal cord
EXPL/CTM-CTM/0995/2021
Investigador
Instituto de Biotecnologia e Bioengenharia, Portugal
 Fundação para a Ciência e a Tecnologia
2021/03/01 - Atual DentalBioMatrix- Exploiting the power of decellularized extracellular matrix to fabricate hierarchical biomimetic scaffolds to regenerate functional periodontal tissues
PTDC/BTM-MAT/3538/2020
Investigador responsável
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020 - Atual SMART: New technologies for Stem cell Manufacturing bioprocess monitoring and ARTificial intelligence-based modeling
PTDC/EQU-EQU/3853/2020
Investigador
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
 Fundação para a Ciência e a Tecnologia
2016 - Atual I-Corps: Development of a bioengineered organic matrix for enhanced bone regeneration
1462613
Investigador
Rensselaer Polytechnic Institute, Estados Unidos
 National Science Foundation Division of Industrial Innovation and Partnerships
2019/04/01 - 2021/09/30 CARDIOWHEEL - Upscaling the Production of Human Pluripotent Stem Cell-derived Cardiomyocytes using Vertical-Wheel Bioreactors
PTDC/EQU-EQU/29653/2017
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Santos, Mafalda S.; Cordeiro, Rachel; Moura, Carla S.; da Silva, Cláudia L.; Ferreira, Frederico Castelo; Silva, João C.; Carvalho, Marta S.. Autor correspondente: Carvalho, Marta S.. "Decellularized extracellular matrix Polycaprolactone/Chitosan composite nanofibrous scaffolds for periodontal tissue engineering". Trabalho apresentado em 4th International Online Conference on Nanomaterials, 2023.
    https://doi.org/10.3390/IOCN2023-14495
  2. Alexandra B. dos Santos; Cláudia L. da Silva; Marta S. Carvalho. "In Vitro Response of Dental Stem Cells on Decellularized Extracellular Matrix-Derived Hydrogels". Trabalho apresentado em 3rd International Electronic Conference on Applied, 2022.
    10.3390/ASEC2022-13832
  3. Carvalho, Marta S.. "Exploiting the Power of Decellularized ECM for Periodontal Tissue Regeneration". Trabalho apresentado em 3rd International Electronic Conference on Applied, 2022.
    10.3390/asec2022-13767
  4. Barbosa, Frederico; Alberte, Paola S.; Garrudo, Fábio F. F.; Carvalho, Marta S.; Pascoal-Faria, Paula; Ferreira, Frederico C.; Silva, João C.. "Piezoelectric PVDF-TrFE/Hydroxyapatite Nanofibers for Bone Tissue Engineering". 2022.
    10.3390/materproc2022008066
  5. Carvalho, Marta S.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Osteocalcin and osteopontin mediate osteogenic differentiation of mesenchymal stem/stromal cells by controlling the maturation level of mineral species". Trabalho apresentado em American Society of Bone and Mineral Research (ASBMR), Montreal, 2018.
    Publicado
  6. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Biomimetic Matrices for Enhanced Stem Cell-Mediated Osteogenesis". Trabalho apresentado em American Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Charlotte, NC, 2017.
    Publicado • 10.1089/ten.tea.2017.29003.abstracts
  7. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Biomimetic collagen type I gels for enhanced stem cell mediated osteogenesis". Trabalho apresentado em European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS –EU) 2016, Uppsala, 2016.
    Publicado
Artigo em revista
  1. Frederico Barbosa; Fábio F. F. Garrudo; Paola S. Alberte; Leonor Resina; Marta S. Carvalho; Akhil Jain; Ana C. Marques; et al. "Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering". Science and Technology of Advanced Materials (2023): https://doi.org/10.1080/14686996.2023.2242242.
    10.1080/14686996.2023.2242242
  2. Mafalda S. Santos; Alexandra B. dos Santos; Marta S. Carvalho. "New Insights in Hydrogels for Periodontal Regeneration". Journal of Functional Biomaterials (2023): https://doi.org/10.3390/jfb14110545.
    10.3390/jfb14110545
  3. Alves, Laura; Machado, Vanessa; Botelho, João; Mendes, José; Cabral, Joaquim M.S.; da Silva, Cláudia L; Carvalho, Marta S.. Autor correspondente: Carvalho, Marta S.. "Enhanced Proliferative and Osteogenic Potential of Periodontal Ligament Stromal Cells". Biomedicines 11 5 (2023): 1352. http://dx.doi.org/10.3390/biomedicines11051352.
    10.3390/biomedicines11051352
  4. Santos, Mafalda S.; Carvalho, Marta S.; Silva, João C.. Autor correspondente: Carvalho, Marta S.. "Recent Advances on Electrospun Nanofibers for Periodontal Regeneration". Nanomaterials (2023): https://doi.org/10.3390/nano13081307.
    10.3390/nano13081307
  5. Fernandes-Platzgummer, Ana; Cunha, Raquel; Morini, Sara; Carvalho, Marta S.; Moreno-Cid, Juan; Cabral, Joaquim M.S.; da Silva, Cláudia L.. "Optimized operation of a controlled stirred tank reactor system for the production of mesenchymal stromal cells and their extracellular vesicles". Biotechnology and Bioengineering (2023): 10.22541/au.167160787.74320022/v1.
    Aceite para publicação
  6. Carvalho, Marta S.; Nogueira, Diogo E.S.; Cabral, Joaquim M.S.; Rodrigues, Carlos A.V.. Autor correspondente: Carvalho, Marta S.. "Neural progenitor cell-derived extracellular matrix as a new platform for neural differentiation of human induced pluripotent stem cells". Biomaterials and Biosystems (2022): https://doi.org/10.1016/j.bbiosy.2022.100070.
    10.1016/j.bbiosy.2022.100070
  7. Carvalho, Marta S.; Alves, Laura; Bogalho, Isabel; Cabral, Joaquim M. S.; da Silva, Cláudia L.. Autor correspondente: Carvalho, Marta S.. "Impact of Donor Age on the Osteogenic Supportive Capacity of Mesenchymal Stromal Cell-Derived Extracellular Matrix.". Frontiers in cell and developmental biology 9 (2021): 747521. http://europepmc.org/abstract/med/34676216.
    Publicado • 10.3389/fcell.2021.747521
  8. Carvalho, Marta S.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. Autor correspondente: Carvalho, Marta S.. "Bone Matrix Non-Collagenous Proteins in Tissue Engineering: Creating New Bone by Mimicking the Extracellular Matrix". Polymers (2021): https://doi.org/10.3390/polym13071095.
    10.3390/polym13071095
  9. Silva, João C.; Carvalho, Marta S.; Udangawa, Ranodhi N.; Moura, Carla S.; Cabral, Joaquim M. S.; da Silva, Cláudia L.; Ferreira, Frederico Castelo; Vashishth, Deepak; Linhardt, Robert J.. "Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient-tailored bone tissue engineering approach". Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 (2020): 2153-2166. http://dx.doi.org/10.1002/jbm.b.34554.
    Publicado • 10.1002/jbm.b.34554
  10. Carvalho, Marta S.; Silva, João C.; Hoff, Christopher M.; Cabral, Joaquim M.S.; Linhardt, Robert J.; da Silva, Cláudia L.; Vashishth, Deepak. "Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells". Journal of Cellular Physiology (2020):
    Publicado • 10.1002/jcp.29653
  11. Nogueira, Diogo E. S.; Rodrigues, Carlos A. V.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M. S.. "Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors". Journal of Biological Engineering 13 1 (2019): http://dx.doi.org/10.1186/s13036-019-0204-1.
    Publicado • 10.1186/s13036-019-0204-1
  12. Carvalho, Marta S.; Silva, João C.; Cabral, Joaquim M.S.; Silva, Cláudia L.; Vashishth, Deepak. "Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells". Journal of Tissue Engineering and Regenerative Medicine 13 9 (2019): 1544-1558. http://dx.doi.org/10.1002/term.2907.
    Publicado • 10.1002/term.2907
  13. Carvalho, Marta S.; Silva, João C.; Udangawa, Ranodhi N.; Cabral, Joaquim M.S.; Ferreira, Frederico Castelo; da Silva, Cláudia L.; Linhardt, Robert J.; Vashishth, Deepak. "Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering". Materials Science and Engineering: C 99 (2019): 479-490. http://dx.doi.org/10.1016/j.msec.2019.01.127.
    Publicado • 10.1016/j.msec.2019.01.127
  14. Silva, João C.; Carvalho, Marta S.; Han, Xiaorui; Xia, Ke; Mikael, Paiyz E.; Cabral, Joaquim M. S.; Ferreira, Frederico Castelo; Linhardt, Robert J.. "Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices". Glycoconjugate Journal 36 2 (2019): 141-154. http://dx.doi.org/10.1007/s10719-019-09858-2.
    Publicado • 10.1007/s10719-019-09858-2
  15. Carvalho, Marta S; Cabral, Joaquim MS; da Silva, Cláudia L; Vashishth, Deepak. "Synergistic effect of extracellularly supplemented osteopontin and osteocalcin on stem cell proliferation, osteogenic differentiation, and angiogenic properties". Journal of Cellular Biochemistry 120 4 (2018): 6555-6569. http://dx.doi.org/10.1002/jcb.27948.
    Publicado • 10.1002/jcb.27948
  16. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M. S.; da Silva, Cláudia L.; Vashishth, Deepak. "Biomimetic matrices for rapidly forming mineralized bone tissue based on stem cell-mediated osteogenesis". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-32794-4.
    Acesso aberto • 10.1038/s41598-018-32794-4
Artigo em revista (magazine)
  1. Carvalho, Marta S.; Pradhan, Subhran; Jovic, Marija. "Towards a Circular Economy: Zero-Waste Technologies & Initiatives - Intelligence Brief", PreScouter, 2020, https://www.prescouter.com/inquiry/towards-a-circular-economy-zero-waste-technologies-initiatives/.
  2. Carvalho, Marta S.. "Smart biopsies: The next generation of cancer diagnostics", PreScouter, 2019, https://www.prescouter.com/2019/10/smart-biopsies/.
Capítulo de livro
  1. Carvalho, Marta S.. Autor correspondente: Carvalho, Marta S.. "Unraveling the power of extracellular matrix to rescue the effect of aging". In Comprehensive Hematology and Stem Cell Research, Stem Cell Therapy and Regeneration section. Elsevier, 2023.
  2. Silva, João C.; Carvalho, Marta S.; Xia, Ke; Cabral, Joaquim M.S.; da Silva, Claúdia L.; Ferreira, Frederico C.; Vashishth, Deepak; Linhardt, Robert J.. "Glycosaminoglycan disaccharide compositional analysis of cell-derived extracellular matrices using liquid chromatography-tandem mass spectrometry". In Methods in Cell Biology. Elsevier, 2019.
    Publicado • 10.1016/bs.mcb.2019.11.017
Edição de número de revista
  1. Carvalho, Marta S.. "Special issue: "Periodontal Tissue Engineering: challenges and limitations"". Frontiers in Bioengineering (2023):
    Editor convidado
  2. Carvalho, Marta S.; Palza, Humberto. "Special Issue: Decellularized Extracellular Matrix for Tissue Engineering and Regenerative Medicine Applications: Recent Advances, Current Challenges and Future Directions". Frontiers in Medical Technology (2022):
    Editor
Entrada de enciclopédia
  1. Santos, Mafalda S.; Carvalho, Marta S.; Silva, João C.. Autor correspondente: Carvalho, Marta S.. "Currently Available Treatments for Periodontal Disease". In Scholarly Community Encyclopedia, MDPI. MDPI, 2023. https://encyclopedia.pub/entry/42957.
    Aceite para publicação
  2. Carvalho, Marta S.. Autor correspondente: Carvalho, Marta S.. "Non-collagenous proteins in bone ECM". In Scholarly Community Encyclopedia, MDPI, 2021. Non-collagenous proteins in bone ECM.
    Aceite para publicação
Poster em conferência
  1. Barbosa, F.; Garrudo, Fábio F. F.; Alberte, Paola S.; Resina, Leonor; Carvalho, Marta S.; Ferreira, Frederico C.; Silva, João C.. "Novel Piezoelectric and Osteoinductive Electrospun Nanofibers for Bone Tissue Engineering". Trabalho apresentado em 2023 TERMIS-EU Chapter, 2023.
  2. Santos, Mafalda S.; Carvalho, Marta S.; Silva, João C.. Autor correspondente: Carvalho, Marta S.. "Electrospun scaffolds combined with decellularized cell-derived extracellular matrix for periodontal regeneration". Trabalho apresentado em AIMS Meeting, 2023.
  3. Garrudo, Fábio F. F.; Silva, João C.; Resina, Leonor; Barbosa, Frederico; Sordini, Laura; Carvalho, Marta S.; Linhardt, Robert J.; et al.. "Development of electroconductive composites for electrical stimulation of stem cells". Trabalho apresentado em 2023 Termis European Chapter, 2023.
  4. Silva, João C.; Meneses, J.; Barbosa, F.; Marcelino, P.; Garrudo, F. F.; Carvalho, M.S.; Alves, N.; et a. "In silico models guiding the biophysical stimulation of biomimetic scaffolds towards improved osteochondral tissue engineering strategies". Trabalho apresentado em 2nd iBB Workshop, 2022, 2022.
  5. Carvalho, Marta S.; Santos, Mafalda S.; Bettecourt, Alexandra S.; Cabral, Joaquim M.S.; Ferreira, Frederico C.; da Silva, Cláudia L. "Exploiting the power of decellularized ECM for periodontal tissue regeneration". Trabalho apresentado em 2nd iBB Workshop, 2022, 2022.
  6. Silva, João C.; Carvalho, M.S.; Moura, C.S.; Cabral, J.M.S.; da Silva, C.L.; Ferreira, F. C.; Vashishth, Deepak; Linhard. "Boosting the osteogenic potential of additive manufactured polycaprolactone scaffolds through functionalization with cell-derived extracellular matrix". Trabalho apresentado em RESIM 2022, 2022.
  7. Carvalho, Marta S.. Autor correspondente: Carvalho, Marta S.. "Exploiting the Power of Decellularized ECM for Periodontal Tissue Regeneration". Trabalho apresentado em 3rd International Electronic Conference on Applied, 2022.
  8. Nogueira, Diogo E.S.; Rodrigues, Carlos A.V.; Salvador, William O.S.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M. S.. "Expansion and Cardiac Differentiation of Human Pluripotent Stem Cells as Aggregates in Vertical-Wheel Bioreactors". Trabalho apresentado em 27th ESACT Meeting, 2022.
  9. Carvalho, Marta S.; Silva, João C.; Cabral, Joaquim M.S.; Ferreira, Frederico C.; da Silva, Cláudia L.; Linhardt, Robert J.; Vashishth, Deepak. "Exploiting extracellular matrix from MSC:HUVEC co-culture as a scaffold for bone tissue engineering". Trabalho apresentado em 3rd Stem Cell Community Day 2019 (Eppendorf), Lisbon, Portugal, 2019.
  10. Nogueira, Diogo E. S.; Rodrigues, Carlos A. V.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M. S.. "Expansion of Human Pluripotent Stem Cells as Aggregates in Vertical-Wheel Bioreactors". Trabalho apresentado em 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Lisbon, Portugal, 2019.
  11. Rodrigues, Carlos A. V.; Nogueira, Diogo E. S.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M. S.. "Expansion of Human Pluripotent Stem Cells as Aggregates in Vertical-Wheel Bioreactors". Trabalho apresentado em TECHNOBEAT Pre X-Mas Symposium on iPS Based Cell Therapies – From Bench to Bedside, 2019.
  12. Carvalho, Marta S.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Osteocalcin and osteopontin mediate osteogenic differentiation of mesenchymal stem/stromal cells by controlling the maturation level of mineral species". Trabalho apresentado em American Society for Bone and Mineral Research (ASBMR) 2018 Annual Meeting, Montreal, Canada, 2018.
  13. Silva, João C.; Carvalho, Marta S.; Undagawa, Ranodhi N.; Moura, Carla S.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Ferreira, Frederico C.; Vashishth, Deepak; Linhardt, Robert J.. "Extracellular matrix decorated porous polycaprolactone scaffolds for bone tissue engineering". Trabalho apresentado em 26th Annual Meeting of the European Orthopaedic Research Society – EORS 2018, Galway, Ireland., 2018.
  14. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Biomimetic Matrices for Enhanced Stem Cell-Mediated Osteogenesis". Trabalho apresentado em American Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM), 2017, Charlotte, NC, 2017.
  15. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M.S.; da Silva, Cláudia L.. "Biomimetic collagen type I gels for enhanced stem cell mediated osteogenesis". Trabalho apresentado em European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS –EU) 2016, Uppsala, Sweden, 2016.
  16. Carvalho, Marta S.; Poundarik, Atharva A.; Cabral, Joaquim M.S.; da Silva, Cláudia L.; Vashishth, Deepak. "Stem cell mediated bone formation on biomimetic 3-D matrices". Trabalho apresentado em 4th Annual 2015 CBIS NIH Biotechnology Training Retreat, Troy, NY, 2015.
Resumo em conferência
  1. Barbosa, Frederico; Garrudo, Fábio F. F.; Alberte, Paola S.; Carvalho, Marta S.; Ferreira, Frederico Castelo; Silva, João C.. "Novel Piezoelectric and Osteoconductive Nanofibers for Bone Tissue Engineering". Trabalho apresentado em EORS 2023 31st Annual Meeting of the European Orthopaedic Research Society, Porto, 2023.
    Em revisão
  2. Garrudo, Fábio F.F.; Silva, João C.; Marcelino, Pedro; Meneses, João; Barbosa, Frederico; Carvalho, Marta S.; Cabral, Joaquim M.S.; et al. "The combined effect of bioactive cues and electrical stimulation on MSC osteogenic differentiation". Trabalho apresentado em ACS Fall 2023, San Francisco, 2023.
    Em revisão
  3. Carvalho, Marta S.; Cabral, Joaquim M.S.; da Silva, Cláudia L. "Exploring the ECM from young donors to enhance the impaired osteogenic properties of aged cells". Trabalho apresentado em EORS 2023 31st Annual Meeting of the European Orthopaedic Research Society, Porto, 2023.
    Em revisão
  4. Garrudo, F.F; Silva, João C.; Rodrigues, C.A.V.; Meneses, J.; Moura, C.S.; Nogueira, D.E.S.; Carvalho, M.S.; et al.. "Electroconductive platforms for the electrical stimulation of stem cells - an approach to the design of artificial human tissue microenvironments". Trabalho apresentado em Polymer Connect 2022, Rome, 2022.
  5. Carvalho, Marta S.; Alves, Laura; Cabral, Joaquim M. S.; da Silva, Cláudia L.. Autor correspondente: Carvalho, Marta S.. "Impact of Donor Age on the Osteogenic Supportive Capacity of Mesenchymal Stromal Cell-Derived Extracellular Matrix". Trabalho apresentado em Ageing without Borders 2022, Faro, 2022.
    Publicado
  6. Nogueira, Diogo E.S.; Rodrigues, Carlos A. V.; Salvador, William O.S.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M.S.. "Development of a High-Density System for the Expansion of Human Induced Pluripotent Stem Cells as Aggregates in Single-Use Vertical-WheelTM Bioreactors". Trabalho apresentado em International Conference on Advanced Research on Sustainability and Intelligent Manufacturing RESIM 2022, Marinha Grande, 2022.
  7. Silva, João C.; Moura, Carla S.; Carvalho, Marta S.; Joaquim M.S. Cabral; Pascoal-Faria, Paula; NUNO F. ALVES; Linhardt, Robert J.; Ferreira, Frederico C.. "Additive manufacturing-based biomimetic/bio-instructive scaffolds and bioreactors for bone, cartilage and osteochondral tissue engineering". Trabalho apresentado em International Conference on Direct Digital Manufacturing and Polymers ICDDMAP 2021, Marinha Grande, 2021.
    Publicado
  8. Nogueira, Diogo E.S.; Rodrigues, Carlos A.V.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M.S.. "Development of a High-Density System for Expansion and Cardiac Differentiation of Human Induced Pluripotent Stem Cells as Aggregates in Single-Use Vertical-WheelTM Bioreactors". Trabalho apresentado em 6th TERMIS World Congress, Maastricht, 2021.
  9. Nogueira, Diogo E.S.; Rodrigues, Carlos A.V.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M.S.. "Expansion and CardiaDifferentiation of Human Induced Pluripotent Stem Cells as Aggregates in Single-Use Vertical-WheelTM Bioreactors". Trabalho apresentado em 12th European Symposium on Biochemical Engineering Sciences, Portoroz, 2021.
  10. Silva, João C.; Carvalho, Marta S.; Udangawa, R. N; Moura, Carla S.; Cabral, Joaquim M.S.; da Silva, Claúdia L.; Ferreira, Frederico C.; Vashishth, Deepak; Linhardt, Robert J.. "Enhancing synthetic scaffolds biological performance and osteoinductive properties using stem cell-derived extracellular matrix". Trabalho apresentado em Polymer Connect 2020 - Polymer Science and Composite Materials Conference, Lisbon, 2020.
    Publicado
  11. Nogueira, Diogo E.S.; Rodrigues, Carlos A.V.; Carvalho, Marta S.; Miranda, Cláudia C.; Hashimura, Yas; Jung, Sunghoon; Lee, Brian; Cabral, Joaquim M.S.. "Strategies for the Expansion of Human Induced Pluripotent Stem Cells as Aggregates in Single-Use Vertical-WheelTM Bioreactors". Trabalho apresentado em ERMIS-EU Chapter Meeting 2020, Manchester, 2020.
  12. Carvalho, Marta S.; Poundarik, Atharva A.; Vashishth, Deepak. "Stem cell mediated bone formation on biomimetic 3-D matrices". Trabalho apresentado em 41st Northeast Bioengineering Conference, 2015.
    Publicado
Tese / Dissertação
  1. Carvalho, Marta S.. "Stem cell-mediated bone formation on biomimetic 3-D matrices". Doutoramento, Universidade de Lisboa Instituto Superior Técnico, 2018.
  2. Carvalho, Marta S.. "Isolation and ex-vivo expansion of endothelial progenitor cells from the umbilical cord blood". Mestrado, Universidade de Lisboa Instituto Superior Técnico, 2012.

Propriedade Intelectual

Patente
  1. Carvalho, Marta S.; Poundarik, Atharva A.; Vashishth, Deepak. 2018. "Biomimetic nano-composite scaffold for enhanced bone healing and fracture repair - WO2016179089A1".
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022 Impact of Donor Age on the Osteogenic Supportive Capacity of Mesenchymal Stromal Cell-Derived Extracellular Matrix Ageing without Borders 2022
2021/10/12 Decellularized ECM as a new biomaterial in Periodontal Tissue Engineering Periodontology Virtual Forum
Osteology Foundation
2021/06/09 DentalBioMatrix Investor Pitch Lab2Market@Técnico 2021
Instituto Superior Técnico, Everis
2021/05/08 Tissue Engineering for Bone Regeneration Under a Biomedical Eye
Biomedical Engineering, Instituto Superior Técnico (NEBM) (Portugal)
2021/02/22 Exploiting the power of extracellular matrix to engineer biomaterials for bone regeneration Jornadas Tecnológicas de Bioquímica
Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Lisboa, Portugal)
2015/10/21 Stem cell mediated bone formation on biomimetic 3-D matrices 4th Annual 2015 CBIS NIH Biotechnology Training Retreat
Rensselaer Polytechnic Institute (Troy, Estados Unidos)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022/02 - 2022/12 Electrospun scaffolds for periodontal ligament regeneration
Orientador de Mafalda Silva Santos
 Integrated Masters in Biomedical Engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/02 - 2022/12 Decellularized ECM-derived hydrogels for periodontal tissue regeneration
Orientador de Alexandra Bettencourt Isabelinha Valério dos Santos
Integrated Masters in Biomedical Engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/03/01 - 2021/12/06 Development of bioengineering strategies for periodontal tissue regeneration - 19/20
Orientador de Laura Sofia Alves
 Integrated Masters in Biological Engineering (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018/02 - 2018/06 Collaboration with Dr. Arduini (RPI) in the RPI Summer Pre-College Teachers Training Program in Stem Cell Biology & Bioengineering. This program partnered teachers from low-income high schools in New York with RPI researchers to design modules on stem cell biology aimed to spark students’ interest in science. (2018/02)
Oficina (workshop)
 Rensselaer Polytechnic Institute, Estados Unidos
2017/03/15 - 2018/04/01 Organization of regular visits of secondary school students from Emma Willard School at Rensselaer Polytechnic Institute, in which students had the opportunity to establish a more personal contact with the researchers in a laboratory environment. (2017/03/15 - 2018/04/01) Rensselaer Polytechnic Institute, Estados Unidos

Emma Willard School, Estados Unidos
2015/04/17 - 2015/04/19 Organization of 41st Northeast Bioengineering Conference (2015/04/17 - 2015/04/19)
Conferência (Outra)
 Rensselaer Polytechnic Institute, Estados Unidos

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2021/02 - Atual Lab2Market@Tecnico2021 - innovation acceleration program (i-Deals/Everis) - Lead a team of researchers and clinicians through an incubation healthcare program (PI) - Worked on market research, value proposition, business model, and go-to-market strategy - Conducted interviews with experts (scientists, investors, consultants, senior management) - Pitched to investors and researchers
Concurso
 Lab2Market@Técnico 2021
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/10/21 - 2015/10/21 NIH Grant Retreat- Involvement and learning about US funding system (presentations and guest speakers). NIH Grant Retreat
Rensselaer Polytechnic Institute, Estados Unidos

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023 Osteoblasts in a Perfusion Flow Bioreactor—Tissue Engineered Constructs of TiO2 Scaffolds and Cells for Improved Clinical Performance
Arguente
 Maria Elisabeth Schröder (Doutoramento)
Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, Noruega
2022/12/03 Electrospun scaffolds for periodontal ligament regeneration
Orientador
 Mafalda Silva Santos (Mestrado)
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2022/12/03 Decellularized ECM-derived hydrogels for periodontal tissue regeneration
Orientador
 Alexandra Santos (Mestrado)
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2022/03/03 Engineering the Formation of Vascular Networks in Human Cerebral Organoids
Arguente principal
 Maria Augusta Barreira Batista (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/12/07 Molecular Regulation of Skeletal Stem/Progenitor Cell Functioning in Bone Formation and Hematopoiesis
Arguente principal
 Maria Carolina Grenho Leal Cordeiro (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Katholieke Universiteit Leuven, Bélgica
2021/12/06 Development of Bioengineering Strategies for Periodontal Tissue Regeneration
Orientador
 Laura Sofia Alves (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/12/03 Electroconductive and Piezoelectric Nanofibers for Osteochondral Tissue Regeneration
Arguente principal
 Frederico Porto de Freitas Barbosa (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/11/25 Breaking down mesenchymal stromal cells: uncovering the potential of decellularized extracellular matrix
Arguente principal
 Catalina Cepeleaga (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/21 Optimization of Mesenchymal Stromal Cell Culture Methodologies Towards the Development of a Cell Therapy for Autoimmune Diseases
Arguente principal
 Ana Lúcia Bastos Tiago (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/12/06 A bioreactor for chondrocyte differentiation: design,modelling and prototyping
Arguente principal
 Pedro Manuel Mesquita Pereira (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/11/18 Co-culture strategies mimicking the fetal liver niche for in vitro expansion of hematopoietic stem cells
Arguente principal
 Isabel Maria Pereira Doutor (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2022 - Atual Frontiers in Endocrinology Frontiers
2022 - Atual Journal of Functional Biomaterials MDPI
2021 - Atual Surgeries (2673-4095) MDPI
2021 - Atual Acta Biomaterialia (1742-7061) Elsevier
2021 - Atual Medicina ( 1010-660X) MDPI
2021 - Atual Archives of Biochemistry and Biophysics Elsevier
2021 - Atual Micromachines MDPI
2021 - Atual Membranes MDPI
2021 - Atual Pharmaceutics MDPI
2021 - Atual Osteology MDPI
2021 - Atual Molecules MDPI
2021 - Atual Biology MDPI
2021 - Atual Biomedical Engineering Advances Elsevier
2021 - Atual Materials Chemistry and Physics Elsevier
2021 - Atual Experimental Cell Research Elsevier
2021 - Atual Journal of Tissue Engineering and Regenerative Medicine Wiley
2021 - Atual Biomolecules MDPI
2021 - Atual Biomedicines MDPI
2020/12 - Atual Biomaterials (0142-9612) Elsevier
2020/12 - Atual Scientific Reports (2045-2322) Nature
2020/01/29 - Atual Biotechnology Journal Wiley
2020/01/14 - Atual Tissue Engineering Part A (1937-335X) Mary Ann Liebert
2020 - Atual Life Sciences (0024-3205) Elsevier
2020 - Atual Cells MDPI
2020 - Atual Applied Sciences MDPI
2019 - Atual International Journal of Molecular Sciences (1422-0067) MDPI
2018/12/17 - Atual Stem Cells International (1687-9678) Hindawi Publishing Corporation (Sage-Hindawi Access to Research)

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2020/01/20 - Atual Development of an Intelligence Brief about companies offering a zero-waste technology or initiative, with a special focus on plastics. PreScouter, Estados Unidos
2016 - 2018 Consultancy activities to Orthograft, a based medical technology start-up that seeks to revolutionize orthopedic regenerative medicine. Orthograft is currently developing bio-inspired materials that harness the power of stem cells and maximize orthopedic regeneration. Orthograft LLC, Estados Unidos

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022 - Atual Cell and Gene Therapy - Masters in Bioengineering: Regenerative and Precision Medicine Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/12 - Atual Biomaterials Technology: Exploiting the power of extracellular matrix to engineer stem cell niches Biomaterials Technology - Integrated Masters in Biomedical Engineering Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/03/01 - 2018/03/31 Biomaterials: development of biomimetic 3-D matrices for osteogenic differentiation of stem cells PhD in Bioengineering, Cell Therapies & Regenerative Medicine (Doutoramento) Universidade de Lisboa Instituto Superior Técnico, Portugal

Rensselaer Polytechnic Institute, Estados Unidos
2017/06/01 - 2017/08/31 Biophysical regulation of stem cells: directing stem cell fate by mechanical cues Pre-College Teachers Training Program in Stem Cell Biology & Bioengineering Rensselaer Polytechnic Institute, Estados Unidos

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2020/02/10 Towards a Circular Economy : New report details promising and innovative zero waste technologies and initiatives that are fueling a more circular economy PreScouter

Membro de associação

Nome da associação Tipo de participação
2023/04 - Atual European Orthopaedic Research Society (EORS) Member
2022/05 - Atual Cellagri Portugal - Associação Portuguesa Para O Desenvolvimento da Agricultura Celular Member
2018 - Atual American Society of Bone and Mineral Research (ASBMR) Member

Tutoria

Tópico Nome do aluno
2015/06/01 - 2018/06/15 Mentoring and Tutoring of undergraduate and MSc students Shawn Varma, Rachael Melita, Annabelle Tang, Kuniko Hunter
Distinções

Prémio

2021 Lab2Market 2021 Finalist
Universidade de Lisboa Instituto Superior Técnico, Portugal

Everis, Espanha
2020 FCT R&D project "DentalBioMatrix" (PTDC/BTM-MAT/3538/2020, 250K€)
Fundação para a Ciência e a Tecnologia, Portugal
2019 Best Poster Presentation Award (2nd place) Eppendorf
Eppendorf AG, Alemanha
2017 Student Scientist Award
TERMIS-AM, Estados Unidos

Outra distinção

2014 PhD Grant - PD/BD/52478/2014
2010 Erasmus Programme Grant