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Alice Santos-Silva is an Associate Professor with Habilitation at the Faculty of Pharmacy, University of Porto, and an Integrated Researcher at the Applied Molecular Biosciences Unit (UCIBIO), from REQUIMTE (Rede de Química e Tecnologia). Her main fields of teaching and research are Hematology, Clinical Biochemistry and Cell Biology. She has collaborated in 17 funded Research Projects, 7 of which as Principal Investigator. With an h-index of 34 (Scopus), Alice Santos-Silva has nearly 300 publications, from which more than 200 articles of original research published in international WoS indexed journals with over 4466 citations, as well as 23 book chapters. She has received 24 scientific awards, and has supervised/co-supervised 24 Doctoral thesis, 53 Master dissertations, and over 80 undergraduate students and post graduate fellows. Her recent research work has been mainly focused on: the mechanisms underlying kidney disease development and progression, and associated complications, such as the effects of gadolinium-based contrast agents; renal anemia and development of resistance to recombinant human erythropoietin treatment in chronic kidney disease; new biomarkers for morbidity and mortality risk in patients on dialysis; new early biomarkers for chronic kidney disease detection and staging; improvement of the biocompatibility of dialysis membranes. Along her research activity, beyond kidney disease, she has been dedicated to the understanding of the pathophysiology of inflammatory diseases associated with physiological (physical exercise, normal and pre-eclamptic pregnancy) and pathological (cardiovascular diseases, psoriasis, obesity) states, namely in the identification of biomarkers of risk.
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Identificação

Identificação pessoal

Nome completo
Alice Santos-Silva

Nomes de citação

  • Santos-Silva, Alice

Identificadores de autor

Ciência ID
3A11-3945-4DC4
ORCID iD
0000-0002-2565-3169
AuthenticusID
AuthID: R-000-AHA
Researcher Id
ResearcherID: K-2326-2013
Scopus Author Id
Scopus Author ID: 6603836490

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Clínica - Urologia e Nefrologia
  • Ciências Médicas e da Saúde - Medicina Clínica - Hematologia
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2004
Concluído
 Ciências Biológicas, sub-grupo II de Biologia Aplicada (Título de Agregado)
Universidade do Porto Faculdade de Farmácia, Portugal
 Aprovada por unanimidade
1995
Concluído
 Farmácia, especialidade de Bioquímica (Doutoramento)
Especialização em Outra:Bioquímica
Universidade do Porto Faculdade de Farmácia, Portugal
"O Eritrocito Como Indicador de Stress in Vivo no Exercício Físico e Nas Doenças Cardiovasculares" (TESE/DISSERTAÇÃO)
1989
Concluído
 Prova de Aptidão Pedagógica e Capacidade Científica (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
 Muito Bom
1982
Concluído
 Ciências Farmacêuticas (Licenciatura)
Universidade de Coimbra Faculdade de Farmácia, Portugal
 15 valores
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/01/01 - Atual Investigador principal (carreira) (Investigação) Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/01/01 - Atual Professor Catedrático (Docente Universitário) Universidade do Porto Faculdade de Farmácia, Portugal
1995 - 2004 Professor Auxiliar (Docente Universitário) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2015 - 2023/12/31 Investigador Integrado REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2008 - 2023/12/31 Associate Professor with Habilitation Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1985 - 2015 Investigador Integrado Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2004 - 2008 Assistant Professor with Habilitation Universidade do Porto Faculdade de Farmácia, Portugal
Projetos

Bolsa

Designação Financiadores
2022/11/18 - Atual Clinical, genetic and early biomarkers of Alport Syndrome
80482
Investigador
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Sociedade Portuguesa de Nefrologia
Em curso
2023/01 - 2025/12 New tools for assessing exposure to food contaminants by monitoring multiple biomarkers in saliva
175598PRJ
Investigador
Fundação para a Ciência e a Tecnologia
2023/03 - 2024/08 Biomarkers for gadolinium renal injury
2022.08400.PTDC
 Fundação para a Ciência e a Tecnologia
2022/09/01 - 2023/08/31 Influence of genetic variants on inflammatory response and on mortality risk in chronic kidney disease patients (SNPsCKD)
SNPsCKD-GI2-CESPU-2022
Investigador
Concluído
2018/07 - 2022/07 Contribution of olive tree and olive oil polyphenols to the prevention of cardiovascular diseases.
Provided by PTCRIS: PTDC/OCE-ETA/32492/2017
 Fundação para a Ciência e a Tecnologia
2019/01 - 2019/12 Unidade de Ciências Biomoleculares Aplicadas
154717UID
 Fundação para a Ciência e a Tecnologia
2011/01 - 2012/12 Projecto Estratégico - LA 2 - 2011-2012
123252UID
 Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2017 - Atual Follow-up study after laparoscopic adjustable gastric banding: characterization of traditional and emergent lipid profile biomarkers
FULAGB/LPB_CESPU_2017
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Em curso
2017 - Atual Clinical and biochemical characterization of “physiological” cholestasis in preterm newborns – a prospective study
2016.085(073-DEFI/070-CES)
Centro Hospitalar Universitário do Porto EPE, Portugal
Em curso
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
10.54499/UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/01/01 - 2022 Dialysis membranes by design: targeting neutrophil elastase to reduce inflammation/oxidative stress in end-stage renal disease (Dial4Life)
PTDC/MEC-CAR/31322/2017
Co-Investigador Responsável (Co-IR)
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016/04 - 2019/12 New technologies for three health challenges of modern societies: diabetes, drug abuse and kidney diseases. Thematic Line - NephroCardio Risk - Reliable biomarkers of chronic kidney disease and of the associated cardiovascular risk. Construction of (bio)sensors for the selected biomarkers
Norte-01-0145-FEDER-000024
Investigador responsável
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2017 Regulation of renal and extra-renal erythropoietin gene expression in anemia induced by chronic renal failure and by acute hypoxia
#165
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - 2017 Mediators of pruritus in cutaneous T-cell lymphomas, mastocytosis and psoriasis
PM.CTCL/MAST/PSO-CESPU-2016
Concluído
2013/05 - 2015/09 Genetic predisposition versus the effect of regular physical exercise on circulating adipokine levels in obese Portuguese adolescents
Provided by PTCRIS: 124757
 Fundação para a Ciência e a Tecnologia, I.P.
2014 - 2015 Etiological assessment of anemia in the elderly in a central hospital in northern Portugal
230/13(145-DEFI/184-CES)
Centro Hospitalar Universitário do Porto EPE, Portugal
Concluído
2011/01 - 2014/07 Cross-talk between chronic renal failure, inflammation and erythropoiesis in resistance to recombinant human erythropoietin therapy
Provided by PTCRIS: 114253
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2012/01/01 - 2012/12 REGULATION OF ERYTHROPOIETIN GENE EXPRESSION IN NON-RENAL TISSUES
REISF02
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009/02 - 2012/11 Risk for cardiovascular events in chronic kidney disease patients under haemodialysis. Lipid profile, anemia, vascular access and inflammation.
Provided by PTCRIS: 83221
 Fundação para a Ciência e a Tecnologia, I.P.
2011 - 2012 Adipocytokines, C-reactive protein, oxidized LDL (oxLDL), oxLDL-b2-glycoprotein I and heat shock protein-70 levels in Portuguese type 2 diabetics according to overweight/obesity measures and with duration of disease
06-2011-CITS/CESPU
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Concluído
2009 - 2012 Value of flow cytometry in the diagnosis and biological study, and evolution of membrane erythrocyte disorders
PIC/IC/83115/2007
Investigador responsável
Fundação para a Ciência e a Tecnologia, Portugal
Concluído
2009 - 2010 Adipocytokines levels and lipid profile in Portuguese patients with psoriasis vulgaris
01/09/CITS/CESPU
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Concluído
2005/09 - 2008/12 Prognostic value of inflammatory and oxidative stress markers in psoriasis
Provided by PTCRIS: 58600
 Fundação para a Ciência e a Tecnologia, I.P.
2005/06 - 2008/10 Cardiovascular risk factors in women with a history of pre-eclampsia
Provided by PTCRIS: 60514
 Fundação para a Ciência e a Tecnologia, I.P.
1995 - 2000 Reliable molecular markers for increased physiological risk
PRAXIS/2/2.1/SAU/1240/95
Fundação para a Ciência e a Tecnologia, Portugal
Concluído
Produções

Publicações

Artigo em conferência
  1. Reis Sousa, Nícia; Santos-Silva, Alice; Coimbra, Susana; Valente, Maria João. "NEPHROTOXIC MECHANISMS OF GADOLINIUM: IMPLICATIONS FOR THE USE OF GADOLINIUM-BASED CONSTRAST AGENTS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    Publicado • 10.1093/ndt/gfab079.004
  2. Coimbra, Susana; Catarino, Cristina; Faria, Maria do Sameiro; Lopes Nunes, José Pedro; Rocha, Susana; Valente, Maria João; Rocha-Pereira, Petronila; et al. "INTERPLAY BETWEEN GDF-15 AND LEFT VENTRICULAR HYPERTROPHY IN END-STAGE RENAL DISEASE PATIENTS ON DIALYSIS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    10.1093/ndt/gfab097.0015
  3. Rocha, Susana; Valente, Maria João; Coimbra, Susana; Catarino, Cristina; Rocha-Pereira, Petronila; Oliveira, José Gerardo; Madureira, José; et al. "INTERLEUKIN-6 (-174G/C) POLYMORPHISM, RS1800795, IN ESRD PATIENTS' OUTCOME*". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    10.1093/ndt/gfab098.002
  4. Kamasová, Terézia; Abreu, Ana Sofia; Paiva-Martins, Fátima; Belo, Luís; Santos-Silva, Alice; Valente, Maria João. "PHYTOTHERAPY ON RENAL HYPOXIA: THE PREVENTIVE EFFECTS OF HYDROXYTYROSOL - PRELIMINARY IN VITRO RESULTS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    10.1093/ndt/gfab113.004
  5. Lousa, Irina; Valente, Maria João; Rocha, Susana; D. Viana, Sofia; Preguiça, Inês; Mira, Filipe; Nogueira, Rui; et al. "PRELIMINARY STUDY OF POTENTIAL BIOMARKERS FOR EARLY DIAGNOSIS IN CHRONIC KIDNEY DISEASE". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    10.1093/ndt/gfab090.0034
  6. Valente, Maria João; Rocha, Susana; Lousa, Irina; Reis, Flávio; Nunes, Sara; D. Viana, Sofia; Preguiça, Inês; et al. "PANEL OF SENSITIVE BIOMARKERS OF THE PRIMARY RESPONSE TO RENAL INJURY FOR AN EARLY DIAGNOSIS OF CHRONIC KIDNEY DISEASE". Trabalho apresentado em Nephrology Dialysis Transplantation, 2020.
    10.1093/ndt/gfaa142.p0739
  7. Coimbra, Susana; Reis, Flávio; Nunes, Sara; D. Viana, Sofia; Valente, Maria João; Rocha, Susana; Catarino, Cristina; et al. "IMPACT OF ACHIEVING LDL CHOLESTEROL LOWER THAN 100 MG/DL WITH STATINS, ON LIPID PROFILE AND INFLAMMATION IN END-STAGE RENAL DISEASE PATIENTS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2020.
    10.1093/ndt/gfaa142.p1581
  8. Rocha, Susana; Valente, Maria João; Coimbra, Susana; Catarino, Cristina; Rocha-Pereira, Petronila; Faria, Maria do Sameiro; Oliveira, José Gerardo; et al. "INTERLEUKIN-6 (RS1800795) AND PENTRAXIN 3 (RS2305619) GENETIC POLYMORPHISMS AND THEIR RELATION WITH INFLAMMATION AND ALL-CAUSE MORTALITY IN ESRD PATIENTS ON DIALYSIS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2020.
    10.1093/ndt/gfaa142.p1570
  9. Faria, Maria do Sameiro; Valente, Maria João; Rocha, Susana; Coimbra, Susana; Catarino, Cristina; Rocha-Pereira, Petronila; Bronze-da-Rocha, Elsa; et al. "DIURETIC USE IN HEMODIALYSIS PATIENTS: BENEFIC ASSOCIATION WITH RESIDUAL RENAL FUNCTION AND ALL-CAUSE MORTALITY". Trabalho apresentado em Nephrology Dialysis Transplantation, 2020.
    10.1093/ndt/gfaa142.p1531
  10. Catarino, Cristina; Faria, Maria do Sameiro; Lopes Nunes, José Pedro; Rocha, Susana; Valente, Maria João; Coimbra, Susana; Rocha-Pereira, Petronila; et al. "ASSOCIATION OF LEFT VENTRICULAR HYPERTROPHY AND ADIPOCYTOKINES IN PATIENTS ON DIALYSIS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2020.
    10.1093/ndt/gfaa142.p1263
  11. Rocha, S; Nascimento, H; Valente, MJ; Coimbra, S; Bronze Da Rocha, E; Catarino, C; Rocha Pereira, P; et al. "INFLAMMATION AND CELL-FREE DNA AS BIOMARKERS FOR THE OUTCOME OF END STAGE RENAL DISEASE PATIENTS". 2019.
    10.1093/ndt/gfz103.sp637
  12. Pedroso, JP; Valente, MJ; Rocha, S; Coimbra, S; Catarino, C; Rocha Pereira, P; Bronze Da Rocha, E; et al. "MACHINE LEARNING IN PREDICTION OF VULNERABLE OR RESILIENT END-STAGE RENAL DISEASE PATIENTS". 2019.
    10.1093/ndt/gfz103.sp666
  13. Valente, MJ; Rocha, S; Coimbra, S; Catarino, C; Rocha Pereira, P; Bronze Da Rocha, E; Oliveira, JG; et al. "PENTRAXIN 3 IN END-STAGE RENAL DISEASE: MULTIPLE RISK BIOMARKER AND PREDICTOR OF ALL-CAUSE MORTALITY". 2019.
    10.1093/ndt/gfz106.fp725
  14. Catarino, Cristina; Rocha, Susana; Valente, Maria João; Coimbra, Susana; Rocha-Pereira, Petronila; Bronze-Da-Rocha, Elsa; Sá-Fernandes, Vitor; et al. "ASSOCIATION OF PTX3, NT-proBNP AND LEFT VENTRICULAR HYPERTROPHY IN PATIENTS ON DIALYSIS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2019.
    10.1093/ndt/gfz103.sp543
  15. Kohlová, Michaela; Amorim, G Célia; Solich, Petr; Rocha, Susana; Valente, Maria João; Santos-Silva, Alice; Montenegro, Conceicao. "LIPOIC ACID COATED POLYSULFONE FLAT SHEET MEMBRANE - NEW AP-PROACH TO REDUCE OXIDATIVE STRESS IN HAEMODIALYSED PATIENTS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2019.
    10.1093/ndt/gfz106.fp731
  16. Coimbra, Susana; Reis, Flávio; Nunes, Sara; Viana, Sofia; Valente, Maria João; Rocha, Susana; Catarino, Cristina; et al. "EFFECTS OF STATINS THERAPY ON LDL SUBFRACTIONS AND INFLAMMATION, IN END-STAGE RENAL DISEASE PATIENTS ON DIALYSIS". Trabalho apresentado em Nephrology Dialysis Transplantation, 2019.
    10.1093/ndt/gfz106.fp730
  17. Do Sameiro-Faria, Maria; Rocha, Susana; Ribeiro, Sandra; Coimbra, Susana; Catarino, Cristina; Valente, Maria João; Rocha-Pereira, Petronila; et al. "IN DIALYSIS PATIENTS FUROSEMIDE THERAPY IS FAVORABLY RELATED WITH INFLAMMATORY RESPONSE, FIBRINOLYSIS, AND BIOMARKERS OF RESIDUAL RENAL FUNCTION". Trabalho apresentado em Nephrology Dialysis Transplantation, 2019.
    10.1093/ndt/gfz103.sp674
  18. Faria, Maria do Sameiro; Rocha, Susana; Ribeiro, Sandra; Coimbra, Susana; Catarino, Cristina; Valente, Maria Joao; Rocha-Pereira, Petronila; et al. "INFLAMMATORY RESPONSE, FIBRINOLYSIS, AND BIOMARKERS OF RESIDUAL KIDNEY FUNCTION IN HEMODIALYSIS PATIENTS: RELATIONSHIP WITH FUROSEMIDE THERAPY". 2018.
  19. Valente, Maria Joao; Rocha, Susana; Catarino, Cristina; Coimbra, Susana; Rocha-Pereira, Petronila; Bronze-da-Rocha, Elsa; Oliveira, Jose Gerardo; et al. "PENTRAXIN 3 VERSUS GROWTH DIFFERENTIATION FACTOR-15: ASSOCIATION WITH INFLAMMATION, IRON HOMEOSTASIS AND ERYTHROPOIESIS IN END-STAGE RENAL DISEASE PATIENTS". 2018.
    10.1093/ndt/gfy104.sp665
  20. Kohlova, Michaela; Amorim, Celia; Duarte, Ana; Araujo, Alberto; Solich, Petr; Santos-Silva, Alice; Montenegro, Conceicao. "POLYSULFONE FLAT SHEET MEMBRANES PREPARED WITH VITAMINE E AND LIPOIC ACID TO REDUCE OXIDATIVE STRESS IN DIALYSIS". 2018.
  21. Catarino, Cristina; Rocha, Susana; Coimbra, Susana; Amorim, Celia; Valente, Maria Joao; Rocha-Pereira, Petronila; Bronze-da-Rocha, Elsa; et al. "ASSOCIATION OF NT-PRO-BNP WITH ANEMIA, INFLAMMATION AND KIDNEY FUNCTION IN PORTUGUESE DIALYSIS PATIENTS". 2018.
    10.1093/ndt/gfy104.SP348
  22. Coimbra, Susana; Reis, Flavio; Nunes, Sara; Viana, Sofia; Rocha, Susana; Valente, Maria Joao; Catarino, Cristina; et al. "ATHEROGENIC PROPERTIES OF LDL PARTICLES IN ESRD PATIENTS ON HEMODIALYSIS". 2018.
    10.1093/ndt/gfy104.sp261
  23. Coimbra, Susana; Santos-Silva, Alice; Costa, Elisio; Bronze-da-Rocha, Elsa. "DNA DAMAGE IN END STAGE RENAL DISEASE PATIENTS: COMET ASSAY AND CELL FREE DNA". 2018.
    10.1093/ndt/gfy104.sp276
  24. Rocha, Susana; Valente, Maria Joao; Catarino, Cristina; Coimbra, Susana; Rocha-Pereira, Petronila; Bronze-da-Rocha, Elsa; Oliveira, Jose Gerardo; et al. "ENDOTHELIAL (DYS)FUNCTION IN PORTUGUESE ENDSTAGE RENAL DISEASE PATIENTS ON HEMODIALYSIS". 2018.
    10.1093/ndt/gfy104.sp656
  25. Belo, Luis; Rocha, Susana; Valente, Maria Joao; Coimbra, Susana; Catarino, Cristina; Bronze-da-Rocha, Elsa; Carvalho, Marcia; et al. "HEPCIDIN-25 AND TREATMENT WITH ERYTHROPOIESIS STIMULATING AGENTS ARE INDEPENDENTLY RELATED WITH ERYTHROPOIESIS IN CHRONIC HEMODIALYSIS PATIENTS". 2018.
    10.1093/ndt/gfy104.sp342
  26. "Reliability of cryohemolysis test in Hereditary Spherocytosis - a portuguese population study.". Trabalho apresentado em Hema Sphere, 2018.
    Publicado • 10.1016/j.freeradbiomed.2018.04.274
  27. Fernandes, Rafael; Freitas, Bruno; Miranda, Vasco; Costa, Elisio; Santos-Silva, Alice; Bronze-Rocha, Elsa. "POLYMORPHISMS OF THE ELANE GENE PROMOTER REGION IN END-STAGE CHRONIC KIDNEY DISEASE PATIENTS". 2016.
    10.1093/ndt/gfw199.21
  28. Coimbra, Susana; Oliveira, Hugo; Catarino, Cristina; Rocha-Pereira, Petronila; Figueiredo, Americo; Santos-Silva, Alice. "RENAL FUNCTION, INFLAMATION AND PSORIASIS VULGARIS". 2016.
    10.1093/ndt/gfw167.39
  29. Rocha, S.; Cleto, E.; Barbot, J.; Ferreira, F.; Quintanilha, A.; Belo, L.; Lima, M.; Bronze-da-Rocha, E.; Santos-Silva, A.. "IGG MEDIATED OPSONIZATION MECHANISM ACCORDING TO THE UNDERLYING PROTEIN DEFICIENCY IN HEREDITARY SPHEROCYTOSIS: TESTING A HYPOTHESIS". 2016.
  30. Ribeiro, Sandra; Garrido, Patricia; Fernandes, Joao; Vala, Helena; Rocha-Pereira, Petronila; Costa, Elisio; Belo, Luis; Reis, Flavio; Santos-Silva, Alice. "IMPAIRED RENAL ENDOTHELIAL NITRIC OXIDE SYNTHASE AND RETICULOCYTE PRODUCTION AS MODULATORS OF HYPERTENSION INDUCED BY RECOMBINANT HUMAN ERYTHROPOIETIN IN THE RAT". 2016.
    10.1093/ndt/gfw158.17
  31. Loureno, Joana; Serrano, Antonio; Poveda, Veronica; Santos-Silva, Alice; Costa, Elisio. "MALE GENDER AND HYPERTENSION ARE INDEPENDENT VARIABLES ASSOCIATED WITH KIDNEY CANCER IN EUROPE: RESULTS FROM THE SHARE STUDY". 2016.
  32. Ribeiro, S; Garrido, P; Fernandes, J; Rocha Pereira, P; Costa, E; Belo, L; Reis, F; Santos Silva, A. "LIVER IRON IS A MAJOR REGULATOR OF HEPCIDIN GENE EXPRESSION VIA BMP/SMAD PATHWAY IN A RAT MODEL OF CHRONIC RENAL FAILURE UNDER TREATMENT WITH HIGH rHuEPO DOSES". 2016.
    10.1093/ndt/gfw166.05
  33. Poveda, V; Amado, L; Filgueiras, M; Ferreira, R; Teixeira, L; Miranda, V; Santos Silva, A; Paul, C; Costa, E. "SELF REPORTED END STAGE RENAL DISEASE ADHERENCE QUESTIONNAIRE AND ITS ASSOCIATION WITH POTENTIAL BIOMARKERS OF NON ADHERENCE". 2016.
    10.1093/ndt/gfw198.17
  34. Ribeiro, S.; Garrido, P.; Fernandes, J.; Rocha, S.; Rocha-Pereira, P.; Costa, E.; Belo, L.; Reis, F.; Santos-Silva, A.. "RECOMBINANT HUMAN ERYTHROPOIETIN-INDUCED ERYTHROPOIESIS REGULATES HEPCIDIN EXPRESSION OVER IRON IN A RAT MODEL". 2015.
    10.1016/j.bcmd.2016.04.008
  35. Catarino, Cristina; Coimbra, Susana; Gomes, Diana; Belo, Luis; Rocha, Susana; Bicho, Manuel; Rebelo, Irene; Santos-Silva, Alice. "Cell free DNA in Portuguese preeclamptic pregnancy.". 2015.
    10.1016/j.preghy.2014.10.140
  36. Fernandes, Joao; Ribeiro, Sandra; Garrido, Patricia; Sereno, Jose; Costa, Elisio; Reis, Flavio; Santos-Silva, Alice. "TRANSCRIPTOR FACTORS RESPONSIBLE FOR EPO GENE REGULATION, TRIGGERED BY ADMINISTRATION OF RHUEPO HIGH DOSES". 2014.
  37. Catarino, Cristina; Cunha, Paula; Ribeiro, Sandra; Rocha-Pereira, Petronila; Reis, Flavio; Sameiro-Faria, Maria; Miranda, Vasco; et al. "STWEAK AND PTX3 AS MARKERS OF ENDOTHELIAL (DYS) FUNCTION AND INFLAMMATION IN END-STAGE RENAL DISEASE PATIENTS UNDER HEMODIALYSIS". 2014.
  38. Sereno, Jose; Rodrigues-Santos, Paulo; Vala, Helena; Rocha-Pereira, Petronila; Fernandes, Joao; Santos-Silva, Alice; Teixeira, Frederico; Reis, Flavio. "BIOMARKERS OF TRANSITION FROM CYCLOSPORINE-INDUCED RENAL DYSFUNCTION TO NEPHROTOXICITY". 2014.
  39. Moura, Alexandra; Madureira, Jose; Alija, Pablo; Fernandes, Joao Carlos; Oliveira, Jose Gerardo; Lopez, Martin; Filgueiras, Madalena; et al. "EFFECT OF AGING IN THE PERCEPTION OF HEALTH RELATED QUALITY OF LIFE, DIALYSIS ADEQUACY, IRON STATUS, INFLAMMATION AND NUTRITIONAL MARKERS IN END STAGE RENAL DISEASE PATIENTS UNDER ONLINE HEMODIAFILTRATION". 2014.
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Artigo em revista
  1. Teixeira, J.; Bessa, M.J.; Delerue-Matos, C.; Sarmento, B.; Santos-Silva, A.; Rodrigues, F.; Oliveira, M.. "Firefighters' personal exposure to gaseous PAHs during controlled forest fires: A case study with estimation of respiratory health risks and in vitro toxicity". Science of the Total Environment 908 (2024): http://www.scopus.com/inward/record.url?eid=2-s2.0-85178499324&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2023.168364
  2. Rocha, S.; Félix, R.; Valente, M.J.; Bento-Silva, A.; Rebelo, R.; Amorim, C.G.; Araújo, A.D.N.; et al. "Polysulfone Membranes Doped with Human Neutrophil Elastase Inhibitors: Assessment of Bioactivity and Biocompatibility". Membranes 13 1 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85146810686&partnerID=MN8TOARS.
    10.3390/membranes13010089
  3. Santos Silva, E.; Rocha, S.; Candeias Ramos, R.; Coutinho, H.; Catarino, C.; Teixeira, F.; Henriques, G.; et al. "Bile acids profile and redox status in healthy infants". Pediatric Research (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85140460365&partnerID=MN8TOARS.
    10.1038/s41390-022-02350-y
  4. Coimbra, S; Catarino, C; Faria, MS; Nunes, JPL; Rocha, S; Valente, MJ; Rocha Pereira, P; et al. "The Association of Leptin with Left Ventricular Hypertrophy in End-Stage Kidney Disease Patients on Dialysis". BIOMEDICINES (2023):
    10.3390/biomedicines11041026
  5. Melo, D.; Coimbra, S.; Rocha, S.; Santos-Silva, A.. "Inhibition of erythrocyte's catalase, glutathione peroxidase or peroxiredoxin 2 – Impact on cytosol and membrane". Archives of Biochemistry and Biophysics 739 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85150222870&partnerID=MN8TOARS.
    10.1016/j.abb.2023.109569
  6. Lousa, I.; Reis, F.; Viana, S.; Vieira, P.; Vala, H.; Belo, L.; Santos-Silva, A.. "TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD". Biomolecules 13 3 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85151108492&partnerID=MN8TOARS.
    10.3390/biom13030534
  7. Lousa, I.; Belo, L.; Valente, M.J.; Rocha, S.; Preguiça, I.; Rocha-Pereira, P.; Beirão, I.; et al. "Inflammatory biomarkers in staging of chronic kidney disease: elevated TNFR2 levels accompanies renal function decline". Inflammation Research 71 5-6 (2022): 591-602. http://www.scopus.com/inward/record.url?eid=2-s2.0-85128870983&partnerID=MN8TOARS.
    10.1007/s00011-022-01574-2
  8. Coimbra, S.; Rocha, S.; Valente, M.J.; Catarino, C.; Bronze-da-Rocha, E.; Belo, L.; Santos-Silva, A.. "New Insights into Adiponectin and Leptin Roles in Chronic Kidney Disease". Biomedicines 10 10 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85140641014&partnerID=MN8TOARS.
    10.3390/biomedicines10102642
  9. Lousa, I.; Reis, F.; Santos-Silva, A.; Belo, L.. "The Signaling Pathway of TNF Receptors: Linking Animal Models of Renal Disease to Human CKD". International Journal of Molecular Sciences 23 6 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85126895015&partnerID=MN8TOARS.
    10.3390/ijms23063284
  10. Nícia Reis Sousa; Susana Rocha; Alice Santos-Silva; Susana Coimbra; Maria João Valente. "Cellular and molecular pathways underlying the nephrotoxicity of gadolinium". Toxicological Sciences (2021): https://doi.org/10.1093/toxsci/kfab148.
    10.1093/toxsci/kfab148
  11. Santos Silva, Ermelinda; Moreira Silva, Helena; Catarino, Cristina; Dias, Cláudia Camila; Santos-Silva, Alice; Lopes, Ana-Isabel. "Neonatal cholestasis: development of a diagnostic decision algorithm from multivariate predictive models". European Journal of Pediatrics (2021): http://dx.doi.org/10.1007/s00431-020-03886-z.
    Publicado • 10.1007/s00431-020-03886-z
  12. Abreu, M.; Miranda, M.; Castro, M.; Fernandes, I.; Cabral, R.; Santos, A.H.; Fonseca, S.; et al. "IL-31 and IL-8 in Cutaneous T-Cell Lymphoma: Looking for Their Role in Itch". Advances in Hematology 2021 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85112616837&partnerID=MN8TOARS.
    10.1155/2021/5582581
  13. Lousa, I.; Reis, F.; Beirão, I.; Alves, R.; Belo, L.; Santos-Silva, A.. "New potential biomarkers for chronic kidney disease management — A review of the literature". International Journal of Molecular Sciences 22 1 (2021): 1-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098497446&partnerID=MN8TOARS.
    10.3390/ijms22010043
  14. Coimbra, S.; Reis, F.; Valente, M.J.; Rocha, S.; Catarino, C.; Rocha-Pereira, P.; Sameiro-Faria, M.; et al. "Subpopulations of high-density lipoprotein: Friends or foes in cardiovascular disease risk in chronic kidney disease?". Biomedicines 9 5 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106898963&partnerID=MN8TOARS.
    10.3390/biomedicines9050554
  15. Lopes, R.; Costa, M.; Ferreira, M.; Gameiro, P.; Fernandes, S.; Catarino, C.; Santos-Silva, A.; Paiva-Martins, F.. "Caffeic acid phenolipids in the protection of cell membranes from oxidative injuries. Interaction with the membrane phospholipid bilayer". Biochimica et Biophysica Acta - Biomembranes 1863 12 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85113335961&partnerID=MN8TOARS.
    10.1016/j.bbamem.2021.183727
  16. Rocha, S.; Valente, M.J.; Coimbra, S.; Catarino, C.; Rocha-Pereira, P.; Oliveira, J.G.; Madureira, J.; et al. "Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis". Scientific Reports 11 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111081363&partnerID=MN8TOARS.
    10.1038/s41598-021-94075-x
  17. Coimbra, Susana; Rocha, Susana; Nascimento, Henrique; Valente, Maria João; Catarino, Cristina; Rocha-Pereira, Petronila; Sameiro-Faria, Maria; et al. "Cell-free DNA as a marker for the outcome of end-stage renal disease patients on haemodialysis". Clinical Kidney Journal (2020): http://dx.doi.org/10.1093/ckj/sfaa115.
    10.1093/ckj/sfaa115
  18. Michaela Kohlová; Susana Rocha; Célia Gomes Amorim; Alberto Nova Araújo; Alice Santos-Silva; Petr Solich; Maria Conceição Branco da Silva Montenegro. "Doping Polysulfone Membrane with Alpha-Tocopherol and Alpha-Lipoic Acid for Suppressing Oxidative Stress Induced by Hemodialysis Treatment". Macromolecular Bioscience (2020): 2000046-2000046. https://doi.org/10.1002/mabi.202000046.
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  19. Santos Silva, Ermelinda; Almeida, Alexandra; Frutuoso, Simão; Martins, Esmeralda; Valente, Maria João; Santos-Silva, Alice; Lopes, Ana Isabel. "Neonatal Cholestasis Over Time: Changes in Epidemiology and Outcome in a Cohort of 154 Patients From a Portuguese Tertiary Center". Frontiers in Pediatrics 8 (2020): http://dx.doi.org/10.3389/fped.2020.00351.
    10.3389/fped.2020.00351
  20. Michaela Kohlová; Célia Gomes Amorim; Alberto da Nova Araújo; Alice Santos-Silva; Petr Solich; Maria Conceição B. S. M. Montenegro. "In vitro assessment of polyethylene glycol and polyvinylpyrrolidone as hydrophilic additives on bioseparation by polysulfone membranes". Journal of Materials Science (2020): https://doi.org/10.1007/s10853-019-04123-1.
    10.1007/s10853-019-04123-1
  21. Rocha, S.; Rocha-Pereira, P.; Cleto, E.; Ferreira, F.; Belo, L.; Santos-Silva, A.. "Linkage of typically cytosolic peroxidases to erythrocyte membrane – A possible mechanism of protection in Hereditary Spherocytosis". Biochimica et Biophysica Acta - Biomembranes 1862 3 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85077399421&partnerID=MN8TOARS.
    10.1016/j.bbamem.2019.183172
  22. Neves, MMPS; Nouws, HPA; Santos Silva, A; Delerue Matos, C. "Neutrophil gelatinase-associated lipocalin detection using a sensitive electrochemical immunosensing approach". SENSORS AND ACTUATORS B-CHEMICAL (2020):
    10.1016/j.snb.2019.127285
  23. Fernandes, Sara; Ribeiro, Catarina; Paiva-Martins, Fátima; Catarino, Cristina; Santos-Silva, Alice. "Protective effect of olive oil polyphenol phase II sulfate conjugates on erythrocyte oxidative-induced hemolysis". Food & Function 11 10 (2020): 8670-8679. http://dx.doi.org/10.1039/d0fo01690j.
    Publicado • 10.1039/d0fo01690j
  24. Valente, M.J.; Rocha, S.; Coimbra, S.; Catarino, C.; Rocha-Pereira, P.; Bronze-Da-Rocha, E.; Oliveira, J.G.; et al. "Long pentraxin 3 as a broader biomarker for multiple risk factors in end-stage renal disease: Association with all-cause mortality". Mediators of Inflammation 2019 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85069797521&partnerID=MN8TOARS.
    10.1155/2019/3295725
  25. Coimbra, S.; Reis, F.; Nunes, S.; Viana, S.; Valente, M.J.; Rocha, S.; Catarino, C.; et al. "The protective role of adiponectin for lipoproteins in end-stage renal disease patients: Relationship with diabetes and body mass index". Oxidative Medicine and Cellular Longevity 2019 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85062598052&partnerID=MN8TOARS.
    10.1155/2019/3021785
  26. Coimbra, S.; Reis, F.; Ferreira, C.; Nunes, S.; Viana, S.; Catarino, A.; Rocha-Pereira, P.; et al. "Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection". Clinical Biochemistry 63 (2019): 46-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055098184&partnerID=MN8TOARS.
    10.1016/j.clinbiochem.2018.10.007
  27. Lopes, P.; Costa-Rama, E.; Beirão, I.; Nouws, H.P.A.; Santos-Silva, A.; Delerue-Matos, C.. "Disposable electrochemical immunosensor for analysis of cystatin C, a CKD biomarker". Talanta 201 (2019): 211-216. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064044110&partnerID=MN8TOARS.
    10.1016/j.talanta.2019.04.006
  28. Belo, L.; Rocha, S.; Valente, M.J.; Coimbra, S.; Catarino, C.; Bronze-da-Rocha, E.; Rocha-Pereira, P.; et al. "Hepcidin and diabetes are independently related with soluble transferrin receptor levels in chronic dialysis patients". Renal Failure 41 1 (2019): 662-672. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070480055&partnerID=MN8TOARS.
    10.1080/0886022X.2019.1635893
  29. Rocha-Pereira, C.; Silva, V.; Costa, V.M.; Silva, R.; Garcia, J.; Gonçalves-Monteiro, S.; Duarte-Araújo, M.; et al. "Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5)". EXCLI Journal 18 (2019): 697-722. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073354478&partnerID=MN8TOARS.
    10.17179/excli2019-1675
  30. Faustino, V.; Rodrigues, R.O.; Pinho, D.; Costa, E.; Santos-Silva, A.; Miranda, V.; Amaral, J.S.; Lima, R.. "A microfluidic deformability assessment of pathological red blood cells flowing in a hyperbolic converging microchannel". Micromachines 10 10 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85073259699&partnerID=MN8TOARS.
    10.3390/mi10100645
  31. Garakanidze, S.; Costa, E.; Bronze-Rocha, E.; Santos-Silva, A.; Nikolaishvili, G.; Nakashidze, I.; Kakauridze, N.; et al. "Characterization of a cohort of patients with arterial thrombosis from the Georgian Adjarian population". Current Trends in Biotechnology and Pharmacy 13 3 (2019): 259-269. http://www.scopus.com/inward/record.url?eid=2-s2.0-85078569331&partnerID=MN8TOARS.
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  33. Costa, A.S.G.; Alves, R.C.; Vinha, A.F.; Costa, E.; Costa, C.S.G.; Nunes, M.A.; Almeida, A.A.; Santos-Silva, A.; Oliveira, M.B.P.P.. "Nutritional, chemical and antioxidant/pro-oxidant profiles of silverskin, a coffee roasting by-product". Food Chemistry 267 (2018): 28-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016070194&partnerID=MN8TOARS.
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  34. Santos, C.; Turiel, S.; Sousa Gomes, P.; Costa, E.; Santos-Silva, A.; Quadros, P.; Duarte, J.; Battistuzzo, S.; Fernandes, M.H.. "Vascular biosafety of commercial hydroxyapatite particles: Discrepancy between blood compatibility assays and endothelial cell behavior". Journal of Nanobiotechnology 16 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044299051&partnerID=MN8TOARS.
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  36. Lousa, Irina; Nascimento, Henrique; Rocha, Susana; Catarino, Cristina; Reis, Flavio; Rego, Carla; Santos-Silva, Alice; et al. "Influence of the 6-month physical activity programs on renal function in obese boys". Pediatric Research 83 5 (2018): 1011-1015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000433149900015&KeyUID=WOS:000433149900015.
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  41. Coimbra, Susana; Ferreira, Catia; Belo, Luis; Rocha-Pereira, Petronila; Catarino, Alice; Monteiro, Luis; Catarino, Cristina; Santos-Silva, Alice. "Impact of weight loss on inflammation and red blood cell biomarkers after laparoscopic gastric banding surgery". Journal of Investigative Medicine 66 2 (2018): 304-308. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428919000005&KeyUID=WOS:000428919000005.
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  211. Rocha, S.; Costa, E.; Catarino, C.; Belo, L.; Castro, E.M.B.; Barbot, J.; Quintanilha, A.; Santos-Silva, A.. "Erythropoietin levels in the different clinical forms of hereditary spherocytosis". British Journal of Haematology 131 4 (2005): 534-542. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644810908&partnerID=MN8TOARS.
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  212. Nouws, H.P.A.; Delerue-Matos, C.; Barros, A.A.; Rodrigues, J.A.; Santos-Silva, A.. "Electroanalytical study of fluvoxamine". Analytical and Bioanalytical Chemistry 382 7 (2005): 1662-1668. http://www.scopus.com/inward/record.url?eid=2-s2.0-23244448632&partnerID=MN8TOARS.
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  214. Branca, R.; Costa, E.; Rocha, S.; Coelho, H.; Quintanilha, A.; Cabeda, J.M.; Santos-Silva, A.; Barbot, J.. "Coexistence of congenital red cell pyruvate kinase and band 3 deficiency". Clinical and Laboratory Haematology 26 4 (2004): 297-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-4043100438&partnerID=MN8TOARS.
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  215. Belo, L.; Gaffney, D.; Caslake, M.; Santos-Silva, A.; Pereira-Leite, L.; Quintanilha, A.; Rebelo, I.. "Apolipoprotein e and cholesteryl ester transfer protein polymorphisms in normal and preeclamptic pregnancies". European Journal of Obstetrics Gynecology and Reproductive Biology 112 1 (2004): 9-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346365540&partnerID=MN8TOARS.
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  216. Rocha-Pereira, P.; Santos-Silva, A.; Rebelo, I.; Figueiredo, A.; Quintanilha, A.; Teixeira, F.. "The inflammatory response in mild and in severe psoriasis". British Journal of Dermatology 150 5 (2004): 917-928. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042741188&partnerID=MN8TOARS.
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Capítulo de livro
  1. Joana Teixeira; Francisca Rodrigues; Alice Santos Silva; Cristina Delerue-Matos; Marta Oliveira. "Use of Urinary Creatinine to Assess Occupational Exposure as a Firefighter: A Preliminary Study". 2024.
    10.1007/978-3-031-38277-2_24
  2. Catarino, C.; Coimbra, S.; Belo, L.; Monteiro, L.; Costa, E.; Santos-Silva, A.. "ADJUSTABLE GASTRIC BANDING SURGERY: IMPACT ON INFLAMMATION AND IRON METABOLISM". 163-184. 2020.
  3. Santos-Silva, A.; Ribeiro, S.; Reis, F.; Belo, L.. "Hepcidin in chronic kidney disease anemia". 243-264. 2019.
    10.1016/bs.vh.2019.01.012
  4. Melo, Daniela; Rocha, Susana; Coimbra, Susana; Santos Silva, Alice. "Interplay between Erythrocyte Peroxidases and Membrane". In Erythrocyte. IntechOpen, 2019.
    10.5772/intechopen.83590
  5. Coimbra, Susana; Santos-Silva, Alice; Costa, Elísio; Bronze-da-Rocha, Elsa. "DNA Damage in End-Stage Renal Disease Patients. Assessment by In Vitro Comet Assay and by Cell-Free DNA Quantification". In Genotoxicity - A Predictable Risk to Our Actual World. InTech, 2018.
    10.5772/intechopen.71319
  6. Santos-Silva, Alice. "O sangue como tecido alvo da toxicidade dos xenobióticos". In Toxicologia Fundamental, 233-256. 2018.
  7. Coimbra, Susana; Faria, Maria do Sameiro; Miranda, Vasco; Belo, Luís; Santos-Silva, Alice. "Cardiovascular Risk Factors in End-Stage Renal Disease Patients: The Impact of Conventional Dialysis versus Online-Hemodiafiltration". In Aspects in Dialysis. InTech, 2018.
    10.5772/intechopen.70465
  8. Tavares, R.; Sales, C.M.D.; Matos, P.M.; Santos-Silva, A.; Costa, E.. "Vascular access and quality of life in dialysis patients". In Innovations in Dialysis Vascular Access Surgery. 2017.
  9. Nascimento, Henrique; Coimbra, Susana; Rego, Carla; Santos-Silva, Alice; Belo, Luís. "Adiponectin, Inflammation and Cardiometabolic Risk Factors in Paediatric Obese Patients: Impact of Interventional Studies". In Adiposity - Omics and Molecular Understanding. InTech, 2017.
  10. Ribeiro, Sandra; Belo, Luís; Reis, Flávio; Santos-Silva, Alice. "The HIF System Response to ESA Therapy in CKD-Anemia". In Hypoxia and Human Diseases. InTech, 2017.
  11. Santos-Silva, Alice. "Psoriasis treatment: targeting the IL-23/Th17 axis". In Psoriasis: Epidemiology, Diagnosis and Management Strategies. 2016.
    Publicado
  12. Coimbra, S.; Proença, J.B.; Figueiredo, A.; Santos-Silva, A.. "Psoriasis Treatment: Targeting The IL-23/Th17 Axis". 65-86. 2016.
  13. Catarino, C; Coimbra, S; Belo, L; Monteiro, L; Costa, E; Silva, A. "Adjustable gastric banding surgery: Impact on inflammation and iron metabolism". 2015.
  14. Santos-Silva, Alice; Costa, Elísio; Alves, Rui. "Chronic Kidney Disease". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease, 95-111. Springer International Publishing, 2015.
    10.1007/978-3-319-16018-4_5
  15. Santos-Silva, Alice. "Psoriasis: Psychological Burden and Quality of Life Implications". In Geriatric Psychodermatology: Psychocutaneous Disorders in the Elderly. Nova Science Publishers, 2015.
  16. Santos-Silva, Alice. "Frontiers in Drug Discovery: Erythropoietic Stimulating Agents". In Haematologica. Bentham Science, 2013.
    10.2174/97816080574741130101
  17. Coimbra, S.; Santos-Silva, A.. "Narrow-band ultraviolet light B (UVB) and psoralen plus UVA effect in the circulating levels of biological markers in psoriasis". In Psoriasis: Types, Triggers and Treatment Strategies, 121-142. 2013.
    Publicado
  18. Coimbra, S.; Santos-Silva, A.. "Body mass index (BMI) importance in psoriasis". In New Trends in Body Mass Index Research, 37-57. 2012.
    Publicado
  19. Teixeira-Lemos, E.; Teixeira, H.M.; Piloto, N.; Teixeira, M.; Parada, B.; Rodrigues-Santos, P.; Carvalho, L.; et al. "Cardiometabolic injury due to recombinant human erythropoietin doping for improvement of sports performance: Chronic (training) versus acute (extenuating) aerobic exercise". In Athlete Performance and Injuries, 99-121. 2012.
    Publicado
  20. Tavaria, F.K.; Fernandes, J.; Santos-Silva, A.; Silva, S.B.; Sarmento, B.; Pintado, M.. "Biological activities of chitin, chitosan and respective oligomers". In Focus on Chitosan Research, 171-198. 2011.
    Publicado
  21. Costa, Elisio; Belo, Luis; Santos-Silv, Alice. "Resistance to Recombinant Human Erythropoietin Therapy in Haemodialysis Patients". In Special Problems in Hemodialysis Patients. InTech, 2011.
    10.5772/24178
  22. Santos-Silva, Alice; Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; et al. "Psoriasis Comorbidities and the Incidence of Risk Factors for Cardiovascular Disease Events in Psoriasis". In Psoriasis: Causes, Diagnosis and Treatment. Nova Science Publishers, 2011.
    Publicado
  23. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; Castro, E.; Rocha-Pereira, P.; Santos-Silva, A.. "Psoriasis comorbidities and the incidence of risk factors for cardiovascular disease events in psoriasis". 2011.
  24. Piloto, N.; Teixeira, H. M.; Teixeira-Lemos, E.; Parada, B.; Garrido, P.; Sereno, J.; Ferreira, L.; et al. "Toxicological effects of recombinant human erythropoietin doping: chronic versus acute aerobic exercise". In Acta medicinae legalis et socialis, 275-282. Imprensa da Universidade de Coimbra, 2010.
    10.14195/978-989-26-0173-1_48
  25. Piloto, N.; Teixeira, H. M.; Teixeira-Lemos, E.; Parada, B.; Garrido, P.; Sereno, J.; Pinto, A. F.; et al. "Erythropoietin doping as cause of sudden death in athletes: an experimental study". In Acta medicinae legalis et socialis, 267-274. Imprensa da Universidade de Coimbra, 2010.
    10.14195/978-989-26-0173-1_47
  26. Granjo, Elisa; Moreira, Ilídia; Santos-Silva, Alice; Rebelo, Irene; Nóvoa, Ana; Ribeiro, Letícia; Fraga, Manuela; et al. "Lymphocyte Populations in Hereditary Spherocytosis Pre and Post Splenectomy and Under Oxidative Stress". In Molecular Biology of Hematopoiesis 6, 347-352. Springer US, 1999.
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Resumo em conferência
  1. Rocha, S; Rebelo, R; Amorim, C; Moreira, R; Santos Silva, A; Montenegro, MCBD. "DOPING POLYSULFONE DIALYSIS MEMBRANES WITH HUMAN NEUTROPHIL ELASTASE INHIBITORS - A PROOF-OF-CONCEPT STUDY". 2022.
    10.1093/ndt/gfac079.031
  2. Rocha, Susana; Morgošová, Kristína; Valente, Maria João; Amorim, Célia; Araújo, Alberto; Santos-Silva, Alice; Moreira, Rui; Branco da Silva Montenegro, Maria Conceição. "DOPING POLYSULFONE DIALYSIS MEMBRANES WITH HUMAN NEUTROPHIL ELASTASE INHIBITORS - A PILOT STUDY". Trabalho apresentado em Nephrology Dialysis Transplantation, 2021.
    10.1093/ndt/gfab113.002
  3. Henrique Nascimento; Susana Coimbra; Carla Rego; Alice Santos-Silva; Luís Belo. "Adiponectin, Inflammation and Cardiometabolic Risk Factors in Paediatric Obese Patients: Impact of Interventional Studies". 2017.
    10.5772/65722
  4. Vala, H; Garrido, P; Ribeiro, S; Fernandes, J; Prada, B; Alves, R; Belo, L; et al. "The 5/6 nephrectomized rat as a good model for the study of anaemia associated with functional and structural kidney damage". 2013.
  5. Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Parada, B; Alves, R; Belo, L; et al. "THE 5/6 NEPHRECTOMIZED RAT AS A GOOD MODEL TO STUDY CHRONIC KIDNEY DISEASE". 2013.
  6. Moura, A; Madureira, J; Alija, P; Fernandes, J; Oliveira, JG; Lopez, M; Felgueiras, M; et al. "TYPE OF VASCULAR ACCESS AND LOCATION IN END-STAGE RENAL DISEASE PATIENTS UNDER ONLINE-HEMODIAFILTRATION AND ITS ASSOCIATION WITH PATIENT'S PERCEPTION OF HEALTH-RELATED QUALITY OF LIFE". 2013.
  7. Garrido, P; Teixeira, M; Costa, E; Rodrigues Santos, P; Parada, B; Belo, L; Alves, R; et al. "EARLY RECOMBINANT HUMAN ERYTHROPOIETIN TREATMENT PROMOTES CARDIORENAL CYTOPROTECTION IN A RAT MODEL OF CHRONIC RENAL FAILURE". 2012.
  8. Ribeiro, S; Sameiro Faria, MS; Rocha, S; Rodrigues, S; Catarino, C; Reis, F; Nascimento, H; et al. "ERYTHROCYTE MEMBRANE PROTEIN COMPOSITION AND BAND 3 PROFILE IN CHRONIC KIDNEY DISEASE PATIENTS UNDER ON-LINE HEMODIAFILTRATION". 2012.
  9. Ribeiro, S; Sameiro Faria, MS; Melo, F; Sereno, J; Freitas, I; Mendonca, M; Nascimento, H; et al. "PON1 ACTIVITY IN HEMODIALYSIS PATIENTS: GENETIC AND NON-GENETIC FACTORS". 2012.
  10. Sameiro Faria, MS; Ribeiro, S; Silva, G; Nascimento, H; Rocha Pereira, P; Miranda, V; Vieira, E; et al. "OXIDIZED-LDL AND LIPOPROTEIN (A) LEVELS IN CHRONIC KIDNEY DISEASE PATIENTS UNDER HEMODIALYSIS: INFLUENCE OF ADIPONECTIN AND OF A POLYMORPHISM IN THE APOLIPOPROTEIN (A) GENE". 2012.
  11. Queiros, ML; Cerejo, L; Leander, M; Freitas, I; Cleto, E; Barbot, J; Goncalves, M; et al. "BONE MARROW ERYTHROID CELLS MATURATION BY FLOW CYTOMETRY". 2011.
  12. Coimbra, S; Oliveira, H; Reis, F; Belo, L; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Evaluation of erythrocyte changes in Portuguese psoriatic patients - relation with treatment". 2010.
  13. Santos, AC; Matos, CA; Silva, MA; Perestrelo, SL; Borges, FJ; Ahmeida, T; Ferreira, N; et al. "A new technique to evaluate experimental acute pulmonary oedema using giant unilamellar liposomes". 2010.
    10.1016/j.nucmedbio.2010.04.057
  14. Santos, AC; Matos, CM; Perestrelo, SL; Silva, MA; Borges, FJ; Gano, L; Neves, M; Oliveiros, B. "Evaluation of acute non-cardiogenic experimental pulmonary oedema using giant unilamellar liposomes". 2010.
    10.1016/j.nucmedbio.2010.04.056
  15. Garrido, P; Reis, F; de Lemos, ET; Costa, E; Parada, B; Piloto, N; Sereno, J; et al. "RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY HAS BENEFICIAL CARDIO-RENAL EFFECTS ON MODERATE STAGES OF CHRONIC RENAL FAILURE IN THE RAT". 2009.
  16. Rodrigues, C; Costa, E; Santos Silva, A; Santos, R; Bronze da Rocha, E; Rodrigues, CF; Costa, EM; Santos, MR; Rocha, EB. "CONTRIBUTION OF RED CELL MASS AND UGT1A1 ALLELES IN SERUM BILIRUBIN LEVELS OF THE PORTUGUESE POPULATION". 2009.
  17. Elisio, C; Rocha, S; Rocha Pereira, P; Castro, E; Reis, F; Teixeira, F; Miranda, V; et al. "CROSS-TALK BETWEEN INFLAMMATION AND IRON STATUS, AND ITS ASSOCIATION WITH RESISTANCE TO RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY IN HAEMODIALYSIS PATIENTS". 2009.
  18. Rodrigues, CF; Costa, EM; Santos Silva, A; Santos, MR; Rocha, EB. "GENETIC AND ACQUIRED FACTORS THAT MODULATE SERUM BILIRUBIN LEVELS". 2009.
  19. Piloto, N; Reis, F; Teixeira, HM; Teixeira, DE; Parada, B; Garrido, P; Sereno, J; et al. "RECOMBINANT HUMAN ERYTHROPOIETIN DOPING IN SPORTS - CARDIOVASCULAR EFFECTS IN CHRONIC AND ACUTE AEROBIC EXERCISE IN AN ANIMAL MODEL". 2009.
  20. Teixeira de Lemos, ET; Reis, F; Baptista, S; Pinto, R; Sepodes, B; Vala, H; Rocha Pereira, PR; Santos Silva, AS; Teixeira, F. "PHYSICAL ACTIVITY AS ANTI-INFLAMMATORY THERAPY IN AN ANIMAL MODEL OF TYPE 2 DIABETES". 2008.
    10.1016/s1567-5688(08)70398-2
  21. Costa, E; Lima, M; Rocha, S; Rocha Pereira, P; Castro, E; Miranda, V; Faria, MS; et al. "IL-7 SERUM LEVELS AND LYMPHOPENIA IN HEMODIALYSIS PATIENTS, NON-RESPONDERS TO RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY". 2008.
    10.1016/j.bcmd.2008.02.007
  22. Costa, MS; Rocha, S; Rocha Pereira, P; Castro, E; Miranda, V; Do Sameiro Faria, MD; Loureiro, A; et al. "CHANGES IN RED BLOOD CELLS MEMBRANE PROTEIN COMPOSITION DURING HAEMODIALYSIS PROCEDURE". 2008.
    10.1080/08860220802422036
  23. Malcata, FX; Pereira, A; Leitao, I; Giao, M; Fernandes, J; Pintado, M; Belo, L; Santos Silva, A. "Characterization of antioxidant capacities of 13 medicinal plant extracts". 2007.
  24. Moreiras, A; Coimbra, S; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Figueiredo, A; et al. "Cytogenotoxicity of therapeutic models used in psoriasis vulgaris". 2007.
  25. Costa, E; Rocha, S; Rocha Pereira, P; Castro, E; Miranda, V; Faria, MS; Loureiro, A; et al. "Band 3 as a marker of erythrocyte changes in chronic renal failure". 2007.
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  26. Coimbra, S; Castro, E; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Rocha, S; et al. "C-reactive protein in mild to severe psoriasis vulgaris". 2007.
  27. Paiva Martins, F; Fernandes, J; Santos Silva, A; Belo, L; Borges, F; Rocha, S. "Effect of olive oil polyphenols on erythrocytes oxidative damage". 2007.
  28. Teixeira, F; de Lemos, ET; Reis, F; Baptista, S; Pinto, R; Sepodes, B; Vala, H; Rocha Pereira, P; Santos Silva, A. "Exercise training and the inflammatory response in ZDF (type 2) diabetic rats". 2007.
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  29. Costa, E; Lima, M; Alves, J; Rocha, S; Tente, T; Rocha Pereira, P; Miranda, V; et al. "Cytokine expression of T lymphocytes and its relationship to recombinant human erythropoietin therapy in chronic renal failure patients". 2007.
  30. Coimbra, S; Castro, E; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Rocha, S; et al. "Neutrophil activation associated to psoriasis vulgaris severity". 2007.
  31. Costa, F; Rocha, S; Rocha Pereira, P; Castro, E; Miranda, V; Faria, MS; Loureiro, A; et al. "Neutrophilactivation markers in chronic renal failure patients under haemodialysis and recombinant human erythropoietin". 2007.
  32. Costa, E; Rocha, S; Rocha Pereira, P; Castro, E; Miranda, V; Sameiro Faria, M; Loureiro, A; et al. "Fibrinolytic activity in chronic renal failure patients under haemodialysis and its relationship to recombinant human erythropoietin resistance". 2007.
  33. Rocha, S; Belo, L; Castro, EB; Rocha Pereira, P; Ferreira, F; Cleto, E; Barbot, J; Quintanilha, A; Santos Silva, A. "Protein deficiencies and clinical outcome of hereditary spherocytosis. Is there a relation after all?". 2007.
  34. Rocha, S; Belo, L; Castro, EB; Rocha Pereira, P; Ferreira, E; Cleto, E; Barbot, J; Quintanilha, A; Santos Silva, A. "Prevalence of membrane protein deficiencies in Portuguese patients with hereditary eliptocytosis and hereditary spherocytosis". 2007.
  35. Catarino, C; Rebelo, I; Belo, L; Rocha, S; Castro, EMB; Patricio, B; Qaintanilha, A; Santos Silva, A. "Enclothelial function and fibrinolytic changes in maternal and cord blood in preeclampsia.". 2006.
  36. Coimbra, S; Rocha Pereira, P; Rebelo, I; Rocha, S; Santos Silva, A; Castro, EMB. "The effect of green tea on lipid profile and oxidative stress". 2004.
    10.1016/S1567-5688(04)90487-X
  37. Branca, R; Costa, E; Rocha, S; Coelho, H; Quintanilha, A; Cabeda, JM; Santos Silva, A; Barbot, J. "Co-existence of congenital red cell pyruvate kinase and band 3 deficiency.". 2003.
  38. Belo, L; Santos Silva, A; Rumley, A; Lowe, G; Pereira Leite, L; Quintanilha, A; Rebelo, I. "Tissue plasminogen activator and platelet count in the clinical evaluation of preeclampsia". 2002.
  39. Pereira, PR; Rebelo, I; Santos Silva, A; Figueiredo, A; Ferra, MIA; Quintanilha, A; Teixeira, F. "Leukocyte activation and oxidative stress in psoriasis". 1999.
  40. Granjo, E; Santos Silva, A; Rebelo, I; Novoa, A; Costa, E; Barbot, J; Ribeiro, MM; Quintanilha, A. "Band 3 profile as a marker of oxidative stress in hereditary spherocytosis.". 1998.

Outros

Outra produção
  1. The HIF System Response to ESA Therapy in CKD-Anemia. 2017. Sandra Ribeiro; Luís Belo; Flávio Reis; Alice Santos-Silva. https://doi.org/10.5772%2F65646.
    10.5772/65646
  2. rhEPO for the Treatment of Erythropoietin Resistant Anemia in Hemodialysis Patients – Risks and Benefits. Hemodialysis. 2013. Ribeiro, Sandra; Costa, Elisio; Belo, Luis; Reis, Flavio; Santos-, Alice. http://dx.doi.org/10.5772/52061.
    10.5772/52061
  3. Umbilical Cord Blood Changes in Neonates from a Preeclamptic Pregnancy. From Preconception to Postpartum. 2012. Catarino, Cristina; Rebelo, Irene; Belo, Lus; Quintanilha, Alexandre; Santos-Silv, Alice. http://dx.doi.org/10.5772/31665.
    10.5772/31665
  4. Neutrophil Activation and Erythrocyte Membrane Protein Composition in Stage 5 Chronic Kidney Disease Patients. Chronic Kidney Disease. 2012. Costa, Elsio; Belo, Lus; Santos-Silv, Alice. http://dx.doi.org/10.5772/25530.
    10.5772/25530
  5. Hematological and Biochemical Parameters in Hereditary Spherocytosis Under Oxidative Stress. Molecular Biology of Hematopoiesis 6. 1999. Granjo, Elisa; Santos-Silva, Alice; Rebelo, Irene; Nóvoa, Ana; Costa, Elisio; Barbot, José; Ribeiro, Letícia; et al. http://dx.doi.org/10.1007/978-1-4615-4797-6_41.
    10.1007/978-1-4615-4797-6_42
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/10/01 - Atual Anemia of chronic kidney disease in the elderly
Coorientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2023/10/01 - Atual Acquired aplastic anemia
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2023/10/01 - Atual Multiple Myeloma – Pathophysiology and diagnosis
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2023/10/01 - Atual Immune thrombocytopenia
Orientador
 Clinical analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2023/10/01 - Atual Anemia in pregnant women
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2020 - Atual New biomarkers for chronic kidney disease management
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - Atual Erythrocyte peroxidases in non-immuno hemolytic anemia - friends or foes?
Orientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - Atual Neonatal cholestasis:new insights into pathophysiology and strategies to improve patient diagnosis and prognosis
Coorientador
 Ciências Médicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - Atual Development of new types of biocompatible hemodialysis membranes for separation of biomolecules
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/10/01 - 2022/12/15 Chronic Myeloid Leukemia - from diagnosis to disease monitoring
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2021/10/01 - 2022/12/02 Anemia in Pregnancy
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2021/10/01 - 2022/11/16 Pathophysiology of anemia associated with COVID-19
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2020 - 2021 Deleterious effects of gadolinium in the proximal tubule: potential risks from the use of gadoliniumbased contrast agents.
Coorientador
 Mestrado em Ciências e Técnicas Laboratoriais Forenses (Mestrado)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020 - 2021 Assessment of the biocompatibility of polysulfone hemodialysis membranes modified by immobilization of neutrophil elastase inhibitors.
Coorientador
 Unidade Curricular de Projecto/Estágio da Licenciatura em Bioquímica ICBAS/FFUP (Outra)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2020 Kidney disease and associated complications. Early biomarkers for diagnosis and monitoring of the disease.
Orientador
 Master in Clinical Analysis (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2019 - 2020 Chronic kidney disease. Molecular mechanisms of hypoxia and inflammation in the development of anemia of kidney disease.
Orientador
 Mestrado em Análises Clínicas (Mestrado)
Universidade do Porto, Faculdade de Farmácia, Portugal
2019 - 2020 Study of the importance of erythrocyte antioxidant enzymes in erythropoiesis, using an erythroid precursor-like cell line.
Coorientador
 Unidade Curricular de Projecto/Estágio da Licenciatura em Bioquímica ICBAS/FFUP (Outra)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2020 Targeting inflammation in chronic kidney disease with natural therapies.
Coorientador
 Unidade Curricular de Projecto/Estágio da Licenciatura em Bioquímica ICBAS/FFUP (Outra)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - 2018 Chronic myeloid leukemia
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Hodgkin's lymphoma
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Chronic Lymphocytic Leukemia Type B
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 - 2018 Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency: Clinical and Laboratory Aspects
Orientador
 Clinical Analysis (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2017 Enzymatic mechanism of antioxidant defense in the erythrocyte – cytosol versus membrane
Coorientador
 Bioquímica (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
2016 - 2017 Impact of new biomarkers in the early detection and progression of diabetic kidney disease
Coorientador
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2017 Itching associated to cutaneous T cell lymphomas: learn more to deal better
Coorientador
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2016 Anemia and high therapeutic doses of recombinant human erythropoietin in chronic kidney disease - a linkage of risk?
Orientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Morbid obesity: role of visceral and subcutaneous adipose tissue adipocytes in iron metabolism
Coorientador
 Clinical Analysis (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 "Follow-up" of patients undergoing laparoscopy gastric band surgery. Hematological and Biochemical Study
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 New Oral Anticoagulants
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Pathophysiology of Pruritus in Cutaneous T-cell Lymphona, Mastocytosis and Psoriasis vulgaris
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Acute Myeloid Leukemia in Children: from Diagnosis to Prognosis
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 - 2016 Anemias Associated with changes in iron metabolism.
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016 Evaluation of the "in vitro" hemocompatibility of compounds based on hydroxyapatite and chitosan, of natural origin
Coorientador
 Toxicologia Analítica Clínica e Forense (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016 Pathophysiology of Pruritus in Cutaneous T-Cell Lymphoma - Role of Interleukins 8 and 31
Coorientador
 Medicina (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 - 2016 Acquired Aplastic Anemia
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2015 - 2016 Thrombocytopenias and evaluation of Pseudothrombocytopenias
Coorientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2016 Anemia and high therapeutic doses of recombinant human erythropoietin in chronic kidney disease - a linkage of risk?
Orientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2016 Applications of flow cytometry in the diagnosis of erythrocyte membrane diseases
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015 Polymorphisms of the Promoter Region of the ELANE Gene in Patients with End-stage Renal Disease
Coorientador
 Bioquímica (Mestrado)
Universidade de Aveiro, Portugal
2010 - 2015 Predictors of quality of life for dialysis patients
Coorientador
 Ciências da Saúde (Doutoramento)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2009 - 2015 Predictive biomarkers of mortality in chronic kidney disease patients on hemodialysis. Lipid profile, anemia, vascular access and inflammation.
Orientador
 Ciências Médicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2015 Resistance to recombinant human erythropoietin therapy - studies inexperimental modedels of anemia and chronic kidney disease.
Coorientador
 Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2015 Factors that contribute to the variation in plasma bilirubin levels in the Portuguese population
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Inflammatory and Hematological Changes in Childhood Obesity. Physical Activity Intervention Study
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Automatic Globular Count: Evaluated Parameters, Clinical Significance and Causes of Error
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 The Role of Adipocyte in the Modulation of Erythropoiesis and Iron Metabolism
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Anticoagulant Therapy
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2014 Characteristic immunophenotypic profiles of B-cell lymphoproliferative diseases
Coorientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2014 Microcytic anemias. A study in a population from the North of Portugal
Orientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2008 - 2014 Acitretin and isotretinoin: mitochondrial, cellular and cytogenotoxicity studies. Combined action with antiestrogens, NBUVB or PUVAs
Coorientador
 Ciências e Tecnologias da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2012 - 2013 Effects of olive oil phenol metabolites on oxidative damage in human erythrocytes
Coorientador
 Bioquímica (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2013 Methodologies for studying the mechanisms of senescence and erythrocyte removal
Orientador
 Análises Clínicas
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2013 Modifications in the erythrocyte membrane in leukodepleted blood preserved for transfusion
Coorientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2009 - 2013 Inflammation and atherosclerotic risk in obese children and adolescents. Genetic contribution and follow-up study based on reduction in Body Mass Index (BMI)
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Hematological aspects of aging: physiological, pathological anemia or both?
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Hereditary hemochromatosis
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Transplantation of Hematopoietic Progenitors
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Waldenstrom disease
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2012 Genotoxicity of hydroxytyrosol in lymphocytes
Orientador
 Toxicologia Analítica Clínica e Forense (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2012 Resistance to recombinant human erythropoietin therapy and plasma BMP2 levels in hemodialysis patients
Coorientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2010 - 2012 Iron deficiency and eating frequency in school-age children on Santa Maria Island
Coorientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2009 - 2012 Development of electrochemical immunosensors for celiac disease clinical diagnosis and gluten-free food control
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2011 Hereditary spherocytosis: techniques for laboratory diagnosis of the disease
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2011 Medullary aplasia
Orientador
 Análises Clínicas
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2011 Influence of adiponectin on bilirubin levels in a population of obese children and adolescents
Coorientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2011 - 2011 Oral anticoagulant therapy
Orientador
 Análises Clínicas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010 - 2011 Characterization of the erythrocyte membrane of obese adolescents
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2011 Synthesis of hydroxytyrosol metabolites and evaluation of protective activity in erythrocytes
Coorientador
 Química (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
2010 - 2011 Multiple resistance to therapy
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 - 2010 Genetic polymorphisms associated with thromboembolic disease in hemodialysis patients
Orientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2010 - 2010 Changes in renal tissue associated with erythropoietin treatment in animal models with renal failure induced by nephrectomy
Orientador
 Análises Clínicas e Saúde Pública (Mestrado)
Universidade Católica Portuguesa Instituto de Ciências da Saúde Porto, Portugal
2008 - 2010 Synthesis and evaluation of the antioxidant activity of hydroxytyrosol metabolites
Coorientador
 Química (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
2008 - 2010 Contribution of flow cytometry to the study of reticulocytes and senescent erythrocytes
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2008 - 2010 Thrombocytopenia and platelet indices in HIV patients
Coorientador
 Infecção VIH/SIDA (Mestrado)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2007 - 2010 Characterization of Commercial Bioactive Chitooligosaccharides
Coorientador
2006 - 2010 Biological Aspects Underlying the Clinical Outcome of Hereditary Spherocytosis
Orientador
 Bioquímica (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2010 Prognostic Value of Inflammatory and Oxidative Stress Markers in Psoríasis
Orientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2010 Pathophysiological Analysis of Maternal Changes in Newborns in Normal and Pre-eclamptic Pregnancies
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2009 Contribution of hematimetric indices, provided by automatic counting, in the diagnosis of anemia
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2008 - 2009 Leukocyte activation in obese children and adolescents. Correlation with obesity index
Orientador
 Análises Clínicas (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2009 Resistance to Recombinant Human Erythropoietin Therapy in Hemodialysis Patients
Orientador
 Bioquímica (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2007 Mutagenicity of therapeutic models used in psoriasis
Orientador
 Toxicologia Analítica Clínica e Forense
Universidade do Porto Faculdade de Farmácia, Portugal
2000 - 2004 The effect of tea intake on plasma lipid levels and antioxidant activity
Coorientador
 Controlo de Qualidade (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2000 - 2004 Hereditary spherocytosis: prevalence in the North region and molecular characterization of leukocyte activation
Coorientador
 Ciências Médicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998 - 2003 Inflammatory Modifications in Human Pregnancy
Coorientador
 Bioquímica (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2017/05/06 - Atual Pediatric nephrology Anemia and inflammation CKD, in children (Pós-Graduação) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 - Atual Hematology I and Hematology II Análises Clínicas (Mestrado integrado) Universidade do Porto, Faculdade de Farmácia, Portugal
1990/09/01 - Atual Hematology Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto, Faculdade de Farmácia, Portugal
1985 - Atual Hematology Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto, Faculdade de Farmácia, Portugal
2014/07 - 2022/07 Toxicologia in vitro - Estudos de Genotoxicidade. Teste do micronúcleo Programa Doutoral em Química Sustentável (Curso de doutoramento (conclusão de unidades curriculares)) Universidade do Porto, Faculdade de Farmácia, Portugal
2008 - 2010 Clinical analysis and public health Patologia do Eritrócito (Curso de mestrado (conclusão do curso de especialização)) Universidade Católica Portuguesa Instituto de Ciências da Saúde, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2022/12 - Atual Coordinating Committee of the Applied Biomolecular Sciences Research Unit (UCIBIO)
Membro
2022/12 - Atual Executive Committee (north) of the Applied Biomolecular Sciences Research Unit (UCIBIO)
Membro
2022 - Atual Ethics Committee of Porto University
Membro
 Universidade do Porto, Portugal
2020 - Atual President of the Ethics Committee of Faculty of Pharmacy
Presidente / Vice-presidente
 Universidade do Porto, Faculdade de Farmácia, Portugal
2019 - Atual Monitoring Committee for the Master's in Clinical Analysis, Faculty of Pharmacy, Porto University
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2019 - Atual Scientific Committee of the Master'sin Clinical Analysis, Faculty of Pharmacy, Porto University
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2014/09 - Atual Council of Representatives, Faculty of Pharmacy of the University of Porto
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
1995/09 - Atual Scientific Council, Faculty of Pharmacy, Porto University
Membro
2015 - 2020 Ethics Committee of Faculty of Pharmacy
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2015/09 - 2019/09 Vice-President of the Pedagogical Council, University of Porto Faculty of Pharmacy
Presidente / Vice-presidente
 Universidade do Porto, Faculdade de Farmácia, Portugal
2002 - 2010 Pedagogical Council
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2005/09 - 2009/09 Council of representatives, Faculty of Pharmacy of the University of Porto
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2005/09 - 2006/09 Scientific Committee of the Degree in Pharmaceutical Sciences
Membro
 Universidade do Porto, Faculdade de Farmácia, Portugal
2005/09 - 2006/09 Monitoring Committee for the Degree in Pharmaceutical Sciences University of Porto Faculty of Pharmacy
Membro
1988/09 - 1989/09 Council of Representatives, Faculty of Pharmacy, Porto University
Membro
Distinções

Prémio

2022 Award DaVita 2022 - best research study published in the area of dialysis: ¿Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms association with infammation and all cause mortality in end stage renal disease patients on dialysis
Sociedade Portuguesa de Nefrologia, Portugal
2021 Award DaVita 2021 - best research study published in the area of dialysis: “Cell-free DNA as a marker for the outcome of end-stage renal disease patients on hemodialysis
Sociedade Portuguesa de Nefrologia, Portugal
2011 Award ROCHE
Sociedade Portuguesa de Nefrologia, Portugal

Outra distinção

2023 Best oral communication - Impact of firefighting activity on urinary concentrations of kidney function biomarkers
2023 Best oral communication - Early biomarkers of kidney injury in firefighters exposed to a controlled structure fire
2021 Best oral comunication as e-poster
14th Investigação Jovem da Universidade do Porto, Portugal
2019 Best communication as poster
Universidade do Porto, 12º Encontro de Investigação Jovem da U. Porto (IJUP), Portugal
2017 2nd Best Oral Communication "Impact of weight loss achieved by bariatric surgery on high-density lipoprotein subfractions"
2015 Gerontology UNIFAI Student Award "Geriatric Depression Scale Score predictors in end stage kidney disease patients under online-hemodiafiltration"
2014 Best abstract for young researchers "Regulation of liver and kidney erythropoietin gene expression in a rat model of anemia associated with chronic renal failure"
2014 Best Oral communication "Relation between CDC and WHO BMI z-score with metabolic syndrome and insulin resistance in obese adolescents"
2014 3rd Best Oral Communication "Longitudinal results in a school-based intervention program for Obese Children"
2012 Best abstract for young researchers "Early recombinant human erythropoietin treatment promotes cardiorenal cytoprotection in a rat model of chronic renal failure "
2011 Award ROCHE (7500 euros) for Best oral communication "Cardio-renal anti-apopototic and pro-proliferative effect of recombinant human erythropoietin in a rat model of moderate renal failure - focus on gene expressi" ¿XXV Congresso Português de Nefrologia¿
Sociedade Portuguesa de Nefrologia, Portugal
2011 Best Poster communication "Increased plasma visfatin levels in diabetic and non diabetic hemodialysis patients and its association with endothelial and inflammatory markers" “VIII Congresso de Análises Clínicas e Saúde Pública”
2011 Best Oral Communication "HDLc quality and populations as putative better markers of dyslipidemia and cardiometabolic risk in type 2 diabetes patients than the traditional totla HDLc content" "XIX National Congress of Atherosclerosis"
2011 Best Oral Communication "Erythropoietic response to rhEPO therapy is dependent on the stage of renal failure - an experimental study in nephrectomized rats" "XXVI Potuguese Congress of Nephrology"
Sociedade Portuguesa de Nefrologia, Portugal
2011 Best oral communication "Anti-apoptotic and pro-proliferative action of early erythropoietin therapy in an animal model of moderate chronic renal failure"
2010 Best poster comunication "Erythrocyte damage as a potential marker of the prooxidant and inflammatory status in an obese pediatric Portuguese population"
2010 EDOL best poster and oral discussion “Cytokines and growth factors in Portuguese psoriatic patients – relation with PUVA and NBUVB therapy”
2010 Best poster presentation "Obesidade. Uma visão multidisciplinar"
2008 3rd Best Oral Communication “Adiponectin levels, Apolipoprotein E polymorphism and BMI influence on lipid profile in obese children and adolescents”
2008 Best Oral Comunication “Therapeutic association of retinoic acids and antiestrogens in skin and breast cancer : molecular mechanisms of cytotoxicity”
2008 Best Oral Comunication "“Effect of recombinant human erythropoietin therapy on the cardio-renal anaemia syndrome in an animal model of moderate renal failure”
2008 Best oral communication "Associação terapêutica de ácidos retinoicos e antiestrogénios no cancro da pele e da mama: Mecanismos moleculares de citotoxicidade"
2006 Best oral comunication “Physical exercise and adiponectin in genetically diabetic rats (Zucker Diabetic Fatty)”
2003 Travel grant & Best oral communication "HDL in pre-eclampsia: association with the inflammatory and haemostatic systems"
2002 Athere Award for best oral communication "Lifestyle modification and biochemical markers of atherosclerosis in obese adolescents"
2001 Best oral communication "High competition physical exercise. Increased atherogenic risk?"
2001 Best oral communication "Exercício físico de alta competição. Risco aterogénico acrescido?"
1998 Athere Award for best oral communication “Influência do consumo de bebidas alcoólicas, da dieta e do tabagismo no perfil de risco aterogénico"