| Artigo em revista |
- Anne Everts; Melissa Bergeman; Grant McFadden; Vera Kemp. "Simultaneous Tumor and Stroma Targeting by Oncolytic Viruses".
Biomedicines (2020): https://www.mdpi.com/2227-9059/8/11/474.
10.3390/biomedicines8110474
- Masmudur M. Rahman; Grant McFadden. "Myxoma Virus-Encoded Host Range Protein M029: A Multifunctional Antagonist Targeting
Multiple Host Antiviral and Innate Immune Pathways". Vaccines (2020): https://www.mdpi.com/2076-393X/8/2/244.
10.3390/vaccines8020244
- McFadden, Grant. "Oncolytic Virotherapy with Myxoma Virus". Journal of clinical medicine (2020): https://europepmc.org/articles/PMC7020043.
10.3390/jcm9010171
- McFadden, Grant. "Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses". European journal of pharmacology
(2020): https://doi.org/10.1016/j.ejphar.2020.172991.
10.1016/j.ejphar.2020.172991
- McFadden, Grant. "Oncolytic Viruses and the Immune System: The Dynamic Duo". Molecular therapy. Methods & clinical development
(2020): https://europepmc.org/articles/PMC7015832.
10.1016/j.omtm.2020.01.001
- McFadden, Grant. "Synergistic Combination of Oncolytic Virotherapy and Immunotherapy for Glioma". Clinical cancer research
: an official journal of the American Association for Cancer Research (2020): https://doi.org/10.1158/1078-0432.CCR-18-3626.
10.1158/1078-0432.ccr-18-3626
- McFadden, Grant. "Passing the Torch". PLoS pathogens (2020): https://europepmc.org/articles/PMC6991946.
10.1371/journal.ppat.1008306
- McFadden, Grant. "Ex Vivo Virotherapy with Myxoma Virus to Treat Cancer". Methods in molecular biology (Clifton, N.J.)
(2020): https://doi.org/10.1007/978-1-4939-9794-7_6.
10.1007/978-1-4939-9794-7_6
- McFadden, Grant. "Genome characterization of cetaceanpox virus from a managed Indo-Pacific bottlenose dolphin (Tursiops aduncus)".
Virus research (2020): https://doi.org/10.1016/j.virusres.2020.197861.
10.1016/j.virusres.2020.197861
- McFadden, Grant. "Deriving Immune Modulating Drugs from Viruses-A New Class of Biologics". Journal of clinical medicine
(2020): https://doi.org/10.3390/jcm9040972.
10.3390/jcm9040972
- McFadden, Grant. "Coinfections of Novel Polyomavirus, Anelloviruses and a Recombinant Strain of Myxoma Virus-MYXV-Tol Identified
in Iberian Hares". Viruses (2020): https://doi.org/10.3390/v12030340.
10.3390/v12030340
- Garg, R.R.; Jackson, C.B.; Rahman, M.M.; Khan, A.R.; Lewin, A.S.; McFadden, G.. "Myxoma virus M013 protein antagonizes NF-¿B
and inflammasome pathways via distinct structural motifs". Journal of Biological Chemistry 294 21 (2019): 8480-8489.
http://www.scopus.com/inward/record.url?eid=2-s2.0-85066442007&partnerID=MN8TOARS.
10.1074/jbc.RA118.006040
- McFadden, Grant. "Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm?". Trends in molecular medicine
(2019): https://doi.org/10.1016/j.molmed.2019.04.002.
10.1016/j.molmed.2019.04.002
- McFadden, Grant. "A Virus-Derived Immune Modulating Serpin Accelerates Wound Closure with Improved Collagen Remodeling". Journal
of clinical medicine (2019): https://europepmc.org/articles/PMC6832452.
10.3390/jcm8101626
- McFadden, Grant. "Quantifying Antibody Responses Induced by Antigen-Agnostic Immunotherapies". Molecular therapy. Methods
& clinical development (2019): https://europepmc.org/articles/PMC6677899.
10.1016/j.omtm.2019.06.010
- McFadden, Grant. "Myxoma virus M013 protein antagonizes NF-¿B and inflammasome pathways via distinct structural motifs". The
Journal of biological chemistry (2019): https://doi.org/10.1074/jbc.RA118.006040.
10.1074/jbc.ra118.006040
- McFadden, Grant. "Genetic Characterization of a Recombinant Myxoma Virus in the Iberian Hare (Lepus granatensis)". Viruses
(2019): https://europepmc.org/articles/PMC6631704.
10.3390/v11060530
- McFadden, Grant. "Quantifying Antigen-Specific T Cell Responses When Using Antigen-Agnostic Immunotherapies". Molecular
therapy. Methods & clinical development (2019): https://europepmc.org/articles/PMC6369252.
10.1016/j.omtm.2019.01.012
- McFadden, Grant. "A cautionary note on the selectivity of oncolytic poxviruses". Oncolytic virotherapy (2019): https://europepmc.org/articles/PMC6375109.
10.2147/OV.S189832
- McFadden, Grant. "Parallel adaptation of rabbit populations to myxoma virus". Science (New York, N.Y.) (2019): https://europepmc.org/articles/PMC6433279.
10.1126/science.aau7285
- McFadden, Grant. "Oncolytic virotherapy for small-cell lung cancer induces immune infiltration and prolongs survival". The
Journal of clinical investigation (2019): https://europepmc.org/articles/PMC6546459.
10.1172/JCI121323
- McFadden, Grant. "Poxvirus oncolytic virotherapy". Expert opinion on biological therapy (2019): https://doi.org/10.1080/14712598.2019.1600669.
10.1080/14712598.2019.1600669
- McFadden, Grant. "Author Correction: The wide utility of rabbits as models of human diseases". Experimental & molecular
medicine (2019): https://europepmc.org/articles/PMC6802666.
10.1038/s12276-019-0252-0
- Wolfe, A.; Rahman, M.; McFadden, D.G.; Bartee, E.C.. "Refinement and successful implementation of a scoring system for Myxomatosis
in a susceptible rabbit (Oryctolagus cuniculus) model". Comparative Medicine 68 4 (2018): 280-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060810593&partnerID=MN8TOARS.
10.30802/AALAS-CM-18-000024
- McFadden, Grant. "Virotherapy as Potential Adjunct Therapy for Graft-Vs-Host Disease". Current pathobiology reports
(2018): https://europepmc.org/articles/PMC6290699.
10.1007/s40139-018-0186-6
- McFadden, Grant. "Oncolytic Virus-Mediated RAS Targeting in Rhabdomyosarcoma". Molecular Therapy Oncolytics (2018):
https://europepmc.org/articles/PMC6197336.
10.1016/j.omto.2018.09.001
- McFadden, Grant. "The wide utility of rabbits as models of human diseases". Experimental & molecular medicine (2018):
https://europepmc.org/articles/PMC5964082.
10.1038/s12276-018-0094-1
- McFadden, Grant. "White paper on microbial anti-cancer therapy and prevention". Journal for immunotherapy of cancer
(2018): https://europepmc.org/articles/PMC6091193.
10.1186/s40425-018-0381-3
- McFadden, Grant. "Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of
Serpin Reactive Center Loop Peptides with Improved Therapeutic Function". Biochemistry (2018): https://doi.org/10.1021/acs.biochem.7b01171.
10.1021/acs.biochem.7b01171
- McFadden, Grant. "Serpins: Development for Therapeutic Applications". Methods in molecular biology (Clifton, N.J.)
(2018): https://doi.org/10.1007/978-1-4939-8645-3_17.
10.1007/978-1-4939-8645-3_17
- McFadden, Grant. "Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in
human cancer cells". Scientific reports (2017): https://europepmc.org/articles/PMC5691082.
10.1038/s41598-017-15941-1
- McFadden, Grant. "Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes
to Enhance Graft versus Tumor". Molecular therapy oncolytics (2017): https://europepmc.org/articles/PMC5363758.
10.1016/j.omto.2016.12.002
- McFadden, Grant. "Myxoma Virus dsRNA Binding Protein M029 Inhibits the Type I IFN-Induced Antiviral State in a Highly Species-Specific Fashion".
Viruses (2017): https://europepmc.org/articles/PMC5332946.
10.3390/v9020027
- Villa, N.Y.; Rahman, M.M.; McFadden, G.; Cogle, C.R.. "Therapeutics for graft-versus-host disease: From conventional therapies
to novel virotherapeutic strategies". Viruses 8 3 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85007372767&partnerID=MN8TOARS.
10.3390/V8030085
- McFadden, Grant. "Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies".
Viruses (2016): https://europepmc.org/articles/PMC4810275.
10.3390/v8030085
- McFadden, Grant. "Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian
virus isolates". Proceedings of the National Academy of Sciences of the United States of America (2016): https://europepmc.org/articles/PMC4833222.
10.1073/pnas.1515613113
- McFadden, Grant. "Ex vivo virotherapy with myxoma virus does not impair hematopoietic stem and progenitor cells". Cytotherapy
(2016): https://europepmc.org/articles/PMC4748395.
10.1016/j.jcyt.2015.12.007
- McFadden, Grant. "Vaccinia virus dissemination requires p21-activated kinase 1". Archives of virology (2016): https://doi.org/10.1007/s00705-016-2996-3.
10.1007/s00705-016-2996-3
- McFadden, Grant. "M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival
in a novel immunocompetent mouse model of glioblastoma". Neuro-oncology (2016): https://europepmc.org/articles/PMC4933479.
10.1093/neuonc/now006
- McFadden, Grant. "SAMD9 is an innate antiviral host factor with stress response properties that can be antagonized by poxviruses".
Journal of virology (2015): https://europepmc.org/articles/PMC4300762.
10.1128/JVI.02262-14
- McFadden, Grant. "Evidence for differential viral oncolytic efficacy in an in vitro model of epithelial ovarian cancer metastasis".
Molecular Therapy Oncolytics (2015): https://europepmc.org/articles/PMC4782950.
10.1038/mto.2015.13
- McFadden, Grant. "Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to
cancer cells". Blood (2015): https://europepmc.org/articles/PMC4463738.
10.1182/blood-2014-07-587329
- McFadden, Grant. "The a2,3-sialyltransferase encoded by myxoma virus is a virulence factor that contributes to immunosuppression".
PloS one (2015): https://europepmc.org/articles/PMC4338283.
10.1371/journal.pone.0118806
- McFadden, Grant. "Prevention of EBV lymphoma development by oncolytic myxoma virus in a murine xenograft model of post-transplant
lymphoproliferative disease". Biochemical and biophysical research communications (2015): https://doi.org/10.1016/j.bbrc.2015.03.146.
10.1016/j.bbrc.2015.03.146
- McFadden, Grant. "Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation". Human gene therapy
(2015): https://europepmc.org/articles/PMC4303190.
10.1089/hum.2014.089
- McFadden, Grant. "In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize
with oncolytic myxoma virus against human brain tumor-initiating cells". Neuro-oncology (2015): https://europepmc.org/articles/PMC4490869.
10.1093/neuonc/nou359
- McFadden, Grant. "ATPS-65AN ONCOLYTIC MYXOMA VIRUS CONSTRUCT (M011L KNOCK-OUT) INDUCES APOPTOSIS AND IS A POTENT PRO-APOPTOTIC
THERAPY IN BOTH HUMAN AND IMMUNOCOMPETENT MURINE GLIOBLASTOMA CANCER STEM CELLS MODELS". Neuro-oncology (2015): https://europepmc.org/articles/PMC4638488.
10.1093/neuonc/nov204.65
- McFadden, Grant. "Editorial overview: Oncolytic viruses--replicating virus therapeutics for the treatment of cancer". Current
opinion in virology (2015): https://doi.org/10.1016/j.coviro.2015.07.005.
10.1016/j.coviro.2015.07.005
- McFadden, Grant. "Introducing “Research Matters”". PLoS pathogens (2015): https://europepmc.org/articles/PMC4482019.
10.1371/journal.ppat.1005014
- McFadden, Grant. "The Curious Road from Basic Pathogen Research to Clinical Translation". PLoS pathogens (2015): https://europepmc.org/articles/PMC4481541.
10.1371/journal.ppat.1004997
- McFadden, Grant. "ET-46ONCOLYTIC VIRAL THERAPY FOR MALIGNANT GLIOMAS USING MYXOMA VIRUS DELETED FOR ANTI-APOPTOTIC M11L GENE".
Neuro-oncology (2014): https://europepmc.org/articles/PMC4218142.
10.1093/neuonc/nou255.44
- McFadden, Grant. "Myxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor
activity". PloS one (2014): https://europepmc.org/articles/PMC4199602.
10.1371/journal.pone.0109801
- McFadden, Grant. "Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus". Cancer
research (2014): https://europepmc.org/articles/PMC4281961.
10.1158/0008-5472.CAN-14-0876
- McFadden, Grant. "Recombinant myxoma virus lacking all poxvirus ankyrin-repeat proteins stimulates multiple cellular anti-viral
pathways and exhibits a severe decrease in virulence". Virology (2014): https://europepmc.org/articles/PMC4157118.
10.1016/j.virol.2014.06.021
- McFadden, Grant. "Oncolytic Poxviruses". Annual review of virology (2014): https://europepmc.org/articles/PMC4380149.
10.1146/annurev-virology-031413-085442
- McFadden, Grant. "TUMOUR BIOLOGY". Neuro-oncology (2014): https://europepmc.org/articles/PMC4046298.
10.1093/neuonc/nou082.25
- Davids, J.A.; Dai, E.; Chen, H.; Bartee, M.Y.; Liu, L.; Fortunel, A.; Moyer, R.; Mcfadden, G.; Lucas, A.R.. "Viral anti-inflammatory
proteins target diverging immune pathways with converging effects on arterial dilatation, plaque and apoptosis". European
Journal of Inflammation 12 1 (2014): 131-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899095549&partnerID=MN8TOARS.
10.1177/1721727X1401200113
- Lucas, A.; Eaverly, M.; McFadden, G.; Bryant, M.. "Women in cardiology: The x factor and the heart of medicine". Journal
of Clinical and Experimental Cardiology 5 2 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84900816850&partnerID=MN8TOARS.
10.4172/2155-9880.1000e134
- Lucas, A.; Ambadapadi, S.; Zheng, D.; Chen, H.; Lakshmyya, K.; Progulske-Fox, A.; Krafft, A.; et al. "The virome: Viral ghost
companion, virus wars". Journal of Clinical and Experimental Cardiology 5 8 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84907483274&partnerID=MN8TOARS.
10.4172/2155-9880.1000e136
- Mandl, K.D.; Kohane, I.S.; McFadden, D.; Weber, G.M.; Natter, M.; Mandel, J.; Schneeweiss, S.; et al. "Scalable collaborative
infrastructure for a learning healthcare system (SCILHS): Architecture". Journal of the American Medical Informatics Association
21 4 (2014): 615-620. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902371324&partnerID=MN8TOARS.
10.1136/amiajnl-2014-002727
- McFadden, Grant. "Suppression of collagen-induced arthritis with a serine proteinase inhibitor (serpin) derived from myxoma
virus". Clinical immunology (Orlando, Fla.) (2014): https://doi.org/10.1016/j.clim.2014.05.003.
10.1016/j.clim.2014.05.003
- McFadden, Grant. "Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro
and further improved by hyaluronan in vivo". Molecular cancer (2014): https://europepmc.org/articles/PMC4021541.
10.1186/1476-4598-13-82
- McFadden, Grant. "Are we there yet? The smallpox research agenda using variola virus". PLoS pathogens (2014): https://europepmc.org/articles/PMC4006926.
10.1371/journal.ppat.1004108
- McFadden, Grant. "Viruses for tumor therapy". Cell host & microbe (2014): https://europepmc.org/articles/PMC3963258.
10.1016/j.chom.2014.01.002
- McFadden, Grant. "Evolution of viral sensing RIG-I-like receptor genes in Leporidae genera Oryctolagus, Sylvilagus, and Lepus".
Immunogenetics (2014): https://doi.org/10.1007/s00251-013-0740-7.
10.1007/s00251-013-0740-7
- McFadden, Grant. "Poxviruses and the evolution of host range and virulence". Infection, Genetics and Evolution (2014):
https://europepmc.org/articles/PMC3945082.
10.1016/j.meegid.2013.10.014
- McFadden, Grant. "Histological evaluation of intratumoral myxoma virus treatment in an immunocompetent mouse model of melanoma".
Oncolytic virotherapy (2013): https://europepmc.org/articles/PMC4389688.
10.2147/OV.S37971
- McFadden, Grant. "Myxoma and vaccinia viruses bind differentially to human leukocytes". Journal of virology (2013):
https://europepmc.org/articles/PMC3624393.
10.1128/JVI.03488-12
- McFadden, Grant. "The tanapoxvirus 15L protein is a virus-encoded neuregulin that promotes viral replication in human endothelial
cells". Journal of virology (2013): https://europepmc.org/articles/PMC3592142.
10.1128/JVI.02112-12
- McFadden, Grant. "The serpin solution; targeting thrombotic and thrombolytic serine proteases in inflammation". Cardiovascular
& hematological disorders drug targets (2013): https://doi.org/10.2174/1871529x11313020003.
10.2174/1871529x11313020003
- McFadden, Grant. "Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal
mouse viral infection". Antimicrobial agents and chemotherapy (2013): https://europepmc.org/articles/PMC3754305.
10.1128/AAC.02594-12
- McFadden, Grant. "Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9
to promote expanded host tropism and viral replication". PLoS pathogens (2013): https://europepmc.org/articles/PMC3701710.
10.1371/journal.ppat.1003465
- McFadden, Grant. "Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer
Cell Growth in Mice". Journal of cancer science & therapy (2013): https://europepmc.org/articles/PMC4367486.
10.4172/1948-5956.1000219
- McFadden, Grant. "Evolution and divergence of the mammalian SAMD9/SAMD9L gene family". BMC evolutionary biology (2013):
https://europepmc.org/articles/PMC3685527.
10.1186/1471-2148-13-121
- McFadden, Grant. "Myxoma virus infection promotes NK lysis of malignant gliomas in vitro and in vivo". PloS one (2013):
https://europepmc.org/articles/PMC3677932.
10.1371/journal.pone.0066825
- McFadden, Grant. "Oncolytic myxoma virus: the path to clinic". Vaccine (2013): https://europepmc.org/articles/PMC3755036.
10.1016/j.vaccine.2013.05.056
- McFadden, Grant. "Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent
of anti-viral type-I interferon". PloS one (2013): https://europepmc.org/articles/PMC3675064.
10.1371/journal.pone.0065801
- McFadden, Grant. "Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular
traps". Cell host & microbe (2013): https://doi.org/10.1016/j.chom.2013.01.005.
10.1016/j.chom.2013.01.005
- McFadden, Grant. "Cytokine synergy: an underappreciated contributor to innate anti-viral immunity". Cytokine (2013):
https://europepmc.org/articles/PMC3748162.
10.1016/j.cyto.2013.04.036
- McFadden, Grant. "Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin". Neuro-oncology
(2013): https://europepmc.org/articles/PMC3688014.
10.1093/neuonc/not035
- Chen, H.; Davids, J.A.; Zheng, D.; Bryant, M.; Bot, I.; van Berckel, T.J.C.; Biessen, E.; et al. "The serpin solution; targeting
thrombotic and thrombolytic serine proteases in inflammation". Cardiovascular and Hematological Disorders - Drug Targets
13 2 (2013): 99-110. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888094951&partnerID=MN8TOARS.
10.2174/1871529X11313020003
- McFadden, Grant. "Positive evolutionary selection on the RIG-I-like receptor genes in mammals". PloS one (2013): https://europepmc.org/articles/PMC3842351.
10.1371/journal.pone.0081864
- McFadden, Grant. "Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus".
Journal for immunotherapy of cancer (2013): https://europepmc.org/articles/PMC3990353.
10.1186/2051-1426-1-S1-P137
- McFadden, Grant. "The poxvirus C7L host range factor superfamily". Current opinion in virology (2012): https://europepmc.org/articles/PMC3508084.
10.1016/j.coviro.2012.09.012
- McFadden, Grant. "Oncolytic virotherapy for ovarian cancer". Oncolytic virotherapy (2012): https://europepmc.org/articles/PMC4428588.
10.2147/OV.S31626
- McFadden, Grant. "Virotherapy using myxoma virus prevents lethal graft-versus-host disease following xeno-transplantation
with primary human hematopoietic stem cells". PloS one (2012): https://europepmc.org/articles/PMC3419197.
10.1371/journal.pone.0043298
- McFadden, Grant. "Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia
E3 via its Z-DNA/RNA binding domain". PloS one (2012): https://europepmc.org/articles/PMC3351467.
10.1371/journal.pone.0036823
- McFadden, Grant. "Bugs and drugs: oncolytic virotherapy in combination with chemotherapy". Current pharmaceutical biotechnology
(2012): https://europepmc.org/articles/PMC4373447.
10.2174/138920112800958850
- McFadden, Grant. "Selective purging of human multiple myeloma cells from autologous stem cell transplantation grafts using
oncolytic myxoma virus". Biology of Blood and Marrow Transplantation (2012): https://europepmc.org/articles/PMC3406238.
10.1016/j.bbmt.2012.04.004
- McFadden, Grant. "Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls
the kinetics of myxomatosis in European rabbits". Journal of virology (2012): https://europepmc.org/articles/PMC3347334.
10.1128/JVI.06933-11
- McFadden, Grant. "Acute myeloid leukemia targeting by myxoma virus in vivo depends on cell binding but not permissiveness
to infection in vitro". Leukemia research (2012): https://europepmc.org/articles/PMC3312971.
10.1016/j.leukres.2012.01.020
- McFadden, Grant. "Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models
of disseminated pancreatic cancer". Molecular therapy : the journal of the American Society of Gene Therapy (2012):
https://europepmc.org/articles/PMC3321583.
10.1038/mt.2011.293
- McFadden, Grant. "Myxoma virus-mediated oncolysis of ascites-derived human ovarian cancer cells and spheroids is impacted
by differential AKT activity". Gynecologic oncology (2012): https://europepmc.org/articles/PMC4373451.
10.1016/j.ygyno.2012.01.048
- McFadden, Grant. "Oncolytic virotherapy for hematological malignancies". Advances in virology (2012): https://europepmc.org/articles/PMC3265224.
10.1155/2012/186512
- McFadden, Grant. "Modulation of NF-¿B signalling by microbial pathogens". Nature reviews. Microbiology (2011): https://europepmc.org/articles/PMC3611960.
10.1038/nrmicro2539
- McFadden, Grant. "Intraventricular injection of myxoma virus results in transient expression of viral protein in mouse brain
ependymal and subventricular cells". The Journal of general virology (2011): http://vir.sgmjournals.org/cgi/content/full/92/1/195.
10.1099/vir.0.026690-0
- McFadden, Grant. "PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY". Neuro-oncology (2011): https://europepmc.org/articles/PMC3222964.
10.1093/neuonc/nor158
- McFadden, Grant. "Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-,
IRF5/IRF7-, and IFNAR-Dependent Pathway". Journal of virology (2011): https://europepmc.org/articles/PMC3209359.
10.1128/JVI.00104-11
- McFadden, Grant. "Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by both NLRP3 and multiple
Toll-like receptors, which independently activate the inflammasome and NF-¿B innate response pathways". Journal of virology
(2011): https://europepmc.org/articles/PMC3209384.
10.1128/JVI.00410-11
- McFadden, Grant. "STEM CELLS". Neuro-oncology (2011): https://europepmc.org/articles/PMC3222962.
10.1093/neuonc/nor163
- McFadden, Grant. "Tumor necrosis factor inhibitors from poxviruses with an emphasis on tanapoxvirus-2L protein". Recent
patents on DNA & gene sequences (2011): https://doi.org/10.2174/187221511796392033.
10.2174/187221511796392033
- McFadden, Grant. "Building bridges between plant and animal viruses". Current opinion in virology (2011): https://doi.org/10.1016/j.coviro.2011.10.004.
10.1016/j.coviro.2011.10.004
- McFadden, Grant. "Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain
tumors". Cancer immunology, immunotherapy : CII (2011): https://europepmc.org/articles/PMC4378695.
10.1007/s00262-011-1045-z
- McFadden, Grant. "The current status and future directions of myxoma virus, a master in immune evasion". Veterinary research
(2011): https://europepmc.org/articles/PMC3131250.
10.1186/1297-9716-42-76
- McFadden, Grant. "Production of Myxoma virus gateway entry and expression libraries and validation of viral protein expression".
Current protocols in microbiology (2011): https://europepmc.org/articles/PMC3104670.
10.1002/9780471729259.mc14a02s21
- McFadden, Grant. "Oncolytic virotherapy for pancreatic cancer". Expert reviews in molecular medicine (2011): https://europepmc.org/articles/PMC3230120.
10.1017/S1462399411001876
- McFadden, Grant. "Viral serpin therapeutics from concept to clinic". Methods in enzymology (2011): https://europepmc.org/articles/PMC3558843.
10.1016/B978-0-12-386471-0.00015-8
- McFadden, Grant. "M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host
SAMD9 in human cells". Journal of virology (2011): https://europepmc.org/articles/PMC3067850.
10.1128/JVI.02243-10
- McFadden, Grant. "A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes
undergoing percutaneous coronary intervention". Circulation. Cardiovascular interventions (2010): https://doi.org/10.1161/CIRCINTERVENTIONS.110.953885.
10.1161/circinterventions.110.953885
- McFadden, Grant. "Myxoma virus: propagation, purification, quantification, and storage". Current protocols in microbiology
(2010): https://europepmc.org/articles/PMC2901999.
10.1002/9780471729259.mc14a01s17
- McFadden, Grant. "Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy
and transplant rejection". PloS one (2010): https://europepmc.org/articles/PMC2865544.
10.1371/journal.pone.0010510
- McFadden, Grant. "Myxoma and vaccinia viruses exploit different mechanisms to enter and infect human cancer cells". Virology
(2010): https://europepmc.org/articles/PMC2862966.
10.1016/j.virol.2010.02.027
- McFadden, Grant. "The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics". Microbes
and infection (2010): https://europepmc.org/articles/PMC2998584.
10.1016/j.micinf.2010.08.012
- McFadden, Grant. "Killing a killer: what next for smallpox?". PLoS pathogens (2010): https://europepmc.org/articles/PMC2813274.
10.1371/journal.ppat.1000727
- McFadden, Grant. "On the road to systems biology of host-pathogen interactions". Future microbiology (2010): https://doi.org/10.2217/fmb.09.130.
10.2217/fmb.09.130
- McFadden, Grant. "Oncolytic viral purging of leukemic hematopoietic stem and progenitor cells with Myxoma virus". Cytokine
& growth factor reviews (2010): https://europepmc.org/articles/PMC2881168.
10.1016/j.cytogfr.2010.02.010
- McFadden, Grant. "Adipose-derived stem cells as therapeutic delivery vehicles of an oncolytic virus for glioblastoma". Molecular
therapy : the journal of the American Society of Gene Therapy (2010): https://europepmc.org/articles/PMC2839314.
10.1038/mt.2009.265
- McFadden, Grant. "Pharmacological manipulation of the akt signaling pathway regulates myxoma virus replication and tropism
in human cancer cells". Journal of virology (2010): https://europepmc.org/articles/PMC2838123.
10.1128/JVI.02020-09
- McFadden, Grant. "Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and
synergy with rapamycin". Cancer research (2010): http://cancerres.aacrjournals.org/cgi/content/full/70/2/598.
10.1158/0008-5472.can-09-1510
- Tardif, J.-C.; L'Allier, P.L.; Grégoire, J.; Ibrahim, R.; McFadden, G.; Kostuk, W.; Knudtson, M.; et al. "A randomized controlled,
phase 2 trial of the viral serpin serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention".
Circulation: Cardiovascular Interventions 3 6 (2010): 543-548. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953287029&partnerID=MN8TOARS.
10.1161/CIRCINTERVENTIONS.110.953885
- Lun, X.; Alain, T.; Zemp, F.J.; Zhou, H.; Rahman, M.M.; Hamilton, M.G.; McFadden, G.; et al. "Myxoma virus virotherapy for
glioma in immunocompetent animal models: Optimizing administration routes and synergy with rapamycin". Cancer Research
70 2 (2010): 598-608. http://www.scopus.com/inward/record.url?eid=2-s2.0-76549086994&partnerID=MN8TOARS.
10.1158/0008-5472.CAN-09-1510
- Kim, M.; Williamson, C.T.; Prudhomme, J.; Bebb, D.G.; Riabowol, K.; Lee, P.W.K.; Lees-Miller, S.P.; et al. "The viral tropism
of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status". Oncogene
29 27 (2010): 3990-3996. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954541596&partnerID=MN8TOARS.
10.1038/onc.2010.137
- McFadden, Grant. "10 M-T7: measuring chemokine-modulating activity". Methods in enzymology (2009): https://doi.org/10.1016/S0076-6879(09)05210-0.
10.1016/s0076-6879(09)05210-0
- McFadden, Grant. "The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics".
Advances in experimental medicine and biology (2009): https://doi.org/10.1007/978-1-4419-1601-3_11.
10.1007/978-1-4419-1601-3_11
- McFadden, Grant. "The addition of tumor necrosis factor plus beta interferon induces a novel synergistic antiviral state against
poxviruses in primary human fibroblasts". Journal of virology (2009): https://europepmc.org/articles/PMC2612348.
10.1128/JVI.01376-08
- McFadden, Grant. "Viral TNF inhibitors as potential therapeutics". Advances in experimental medicine and biology (2009):
https://doi.org/10.1007/978-1-4419-1601-3_5.
10.1007/978-1-4419-1601-3_5
- McFadden, Grant. "Interplay between poxviruses and the cellular ubiquitin/ubiquitin-like pathways". FEBS letters (2009):
https://doi.org/10.1016/j.febslet.2009.01.023.
10.1016/j.febslet.2009.01.023
- McFadden, Grant. "Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic
stem and progenitor cells". Leukemia (2009): https://europepmc.org/articles/PMC3277946.
10.1038/leu.2009.219
- McFadden, Grant. "Analysis of vaccinia virus-host protein-protein interactions: validations of yeast two-hybrid screenings".
Journal of proteome research (2009): https://europepmc.org/articles/PMC2738428.
10.1021/pr900491n
- McFadden, Grant. "Co-regulation of NF-kappaB and inflammasome-mediated inflammatory responses by myxoma virus pyrin domain-containing
protein M013". PLoS pathogens (2009): https://europepmc.org/articles/PMC2762494.
10.1371/journal.ppat.1000635
- McFadden, Grant. "Cytokine determinants of viral tropism". Nature reviews. Immunology (2009): https://europepmc.org/articles/PMC4373421.
10.1038/nri2623
- McFadden, Grant. "Abstracts from the 2009 Joint Meeting of the Society for Neuro-Oncology (SNO) and the American Association
of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS) Section on Tumors: October 22–24, 2009: New Orleans,
LA". Neuro-oncology (2009): https://europepmc.org/articles/PMC2765346.
10.1215/15228517-2009-034
- McFadden, Grant. "Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis
factor plus interferon-beta". Cytokine (2009): https://europepmc.org/articles/PMC4376283.
10.1016/j.cyto.2009.06.006
- McFadden, Grant. "Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200)". Journal of virology
(2009): https://europepmc.org/articles/PMC2738222.
10.1128/JVI.01078-09
- McFadden, Grant. "Cowpox virus expresses a novel ankyrin repeat NF-kappaB inhibitor that controls inflammatory cell influx
into virus-infected tissues and is critical for virus pathogenesis". Journal of virology (2009): https://europepmc.org/articles/PMC2738262.
10.1128/JVI.00861-09
- McFadden, Grant. "“Pearls”: A New Type of Open-Access Educational Resource". PLoS pathogens (2009): https://europepmc.org/articles/PMC2695540.
10.1371/journal.ppat.1000499
- McFadden, Grant. "Proteomic screening of variola virus reveals a unique NF-kappaB inhibitor that is highly conserved among
pathogenic orthopoxviruses". Proceedings of the National Academy of Sciences of the United States of America (2009):
https://europepmc.org/articles/PMC2683884.
10.1073/pnas.0900452106
- McFadden, Grant. "Myxoma virus M130R is a novel virulence factor required for lethal myxomatosis in rabbits". Virus research
(2009): https://doi.org/10.1016/j.virusres.2009.05.009.
10.1016/j.virusres.2009.05.009
- McFadden, Grant. "Virology in the 21st century". Journal of virology (2009): https://europepmc.org/articles/PMC2681991.
10.1128/JVI.00151-09
- McFadden, Grant. "Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits". Journal
of virology (2009): https://europepmc.org/articles/PMC2681933.
10.1128/JVI.00204-09
- McFadden, Grant. "Induction of alpha/beta interferon by myxoma virus is selectively abrogated when primary mouse embryo fibroblasts
become immortalized". Journal of virology (2009): https://europepmc.org/articles/PMC2681981.
10.1128/JVI.02587-08
- McFadden, Grant. "Interaction of human TNF and beta2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L". Virology
(2009): https://doi.org/10.1016/j.virol.2009.01.026.
10.1016/j.virol.2009.01.026
- McFadden, Grant. "Myxoma virus selectively disrupts type I interferon signaling in primary human fibroblasts by blocking the
activation of the Janus kinase Tyk2". Virology (2009): https://doi.org/10.1016/j.virol.2009.02.013.
10.1016/j.virol.2009.02.013
- McFadden, Grant. "Poxvirus proteomics and virus-host protein interactions". Microbiology and molecular biology reviews
: MMBR (2009): https://europepmc.org/articles/PMC2786582.
10.1128/MMBR.00026-09
- McFadden, Grant. "The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular
signaling pathways mediated by Akt and Skp1 in virus-infected cells". Journal of virology (2009): https://europepmc.org/articles/PMC2786711.
10.1128/JVI.00963-09
- McFadden, Grant. "NFkB inhibitors: strategies from poxviruses". Cell cycle (Georgetown, Tex.) (2009): https://doi.org/10.4161/cc.8.19.9683.
10.4161/cc.8.19.9683
- McFadden, Grant. "Tumor necrosis factor and interferon: cytokines in harmony". Current opinion in microbiology (2008):
https://europepmc.org/articles/PMC7108444.
10.1016/j.mib.2008.05.015
- McFadden, Grant. "Construction and testing of a novel host-range defective myxoma virus vaccine with the M063 gene inactivated
that is non-permissive for replication in rabbit cells". Veterinary research (2008): https://doi.org/10.1051/vetres:2008037.
10.1051/vetres:2008037
- McFadden, Grant. "RIG-I mediates the co-induction of tumor necrosis factor and type I interferon elicited by myxoma virus
in primary human macrophages". PLoS pathogens (2008): https://europepmc.org/articles/PMC2438611.
10.1371/journal.ppat.1000099
- McFadden, Grant. "PLoS Pathogens at three years". PLoS pathogens (2008): https://europepmc.org/articles/PMC2533063.
10.1371/journal.ppat.1000167
- McFadden, Grant. "When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond". Journal of infection
in developing countries (2008): https://doi.org/10.3855/jidc.258.
10.3855/jidc.258
- McFadden, Grant. "Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo". Molecular therapy : the
journal of the American Society of Gene Therapy (2008): https://europepmc.org/articles/PMC4376281.
10.1038/sj.mt.6300348
- McFadden, Grant. "Yaba monkey tumor virus encodes a functional inhibitor of interleukin-18". Journal of virology (2008):
https://europepmc.org/articles/PMC2224402.
10.1128/JVI.00688-07
- McFadden, Grant. "The role of cell signaling in poxvirus tropism: the case of the M-T5 host range protein of myxoma virus".
Biochimica et biophysica acta (2008): https://doi.org/10.1016/j.bbapap.2007.08.001.
10.1016/j.bbapap.2007.08.001
- McFadden, Grant. "Inclusion of the viral anti-apoptotic molecule M11L in DNA vaccine vectors enhances HIV Env-specific T cell-mediated
immunity". Virology (2008): https://doi.org/10.1016/j.virol.2008.01.011.
10.1016/j.virol.2008.01.011
- McFadden, Grant. "Myxoma virus is oncolytic for human pancreatic adenocarcinoma cells". Annals of surgical oncology
(2008): http://www.annalssurgicaloncology.org/cgi/content/full/15/8/2329.
10.1245/s10434-008-9924-z
- McFadden, Grant. "Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of
rhabdoid tumors". Clinical cancer research : an official journal of the American Association for Cancer Research (2008):
https://europepmc.org/articles/PMC2844789.
10.1158/1078-0432.CCR-07-1330
- McFadden, Grant. "Heparin alters viral serpin, serp-1, anti-thrombolytic activity to anti-thrombotic activity". The open
biochemistry journal (2008): https://europepmc.org/articles/PMC2570549.
10.2174/1874091X00802010006
- McFadden, Grant. "Poxvirus host range genes". Advances in virus research (2008): https://doi.org/10.1016/S0065-3527(08)00003-1.
10.1016/s0065-3527(08)00003-1
- McFadden, Grant. "Innate immunity, tumor microenvironment and oncolytic virus therapy: friends or foes?". Current opinion
in molecular therapeutics (2008): http://europepmc.org/abstract/MED/18228179.
- McFadden, Grant. "Change in the editorial leadership of PLoS Pathogens". PLoS pathogens (2008): https://europepmc.org/articles/PMC2323282.
10.1371/journal.ppat.0040015
- Stanford, M.M.; Breitbach, C.J.; Bell, J.C.; McFadden, G.. "Innate immunity, tumor microenvironment and oncolytic virus therapy:
Friends or foes?". Current Opinion in Molecular Therapeutics 10 1 (2008): 32-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-38649123395&partnerID=MN8TOARS.
- Moussatché, N.; Damaso, C.R.; McFadden, G.. "When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond.".
Journal of infection in developing countries 2 3 (2008): 156-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650700335&partnerID=MN8TOARS.
- McFadden, Grant. "Induction of indefinite cardiac allograft survival correlates with toll-like receptor 2 and 4 downregulation
after serine protease inhibitor-1 (Serp-1) treatment". Transplantation (2007): https://doi.org/10.1097/01.tp.0000286099.50532.b0.
10.1097/01.tp.0000286099.50532.b0
- McFadden, Grant. "Abstracts for the Twelfth Annual Meeting of the Society for Neuro-Oncology: November 15–18, 2007". Neuro-oncology
(2007): https://europepmc.org/articles/PMC1994106.
10.1215/15228517-2007-039
- McFadden, Grant. "Myxoma virus in the European rabbit: interactions between the virus and its susceptible host". Veterinary
research (2007): https://doi.org/10.1051/vetres:2006054.
10.1051/vetres:2006054
- McFadden, Grant. "Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2". Protein science
: a publication of the Protein Society (2007): https://europepmc.org/articles/PMC2203349.
10.1110/ps.062720107
- McFadden, Grant. "Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells". Virology
(2007): https://doi.org/10.1016/j.virol.2006.11.015.
10.1016/j.virol.2006.11.015
- McFadden, Grant. "M-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced
by cellular PIKE-A". Journal of virology (2007): https://europepmc.org/articles/PMC1865929.
10.1128/JVI.01310-06
- McFadden, Grant. "Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for
human tumor cells". Journal of virology (2007): https://europepmc.org/articles/PMC1797522.
10.1128/JVI.01408-06
- McFadden, Grant. "M135R is a novel cell surface virulence factor of myxoma virus". Journal of virology (2007): https://europepmc.org/articles/PMC1797242.
10.1128/JVI.01633-06
- McFadden, Grant. "Immunopathogenesis of poxvirus infections: forecasting the impending storm". Immunology and cell biology
(2007): https://doi.org/10.1038/sj.icb.7100033.
10.1038/sj.icb.7100033
- McFadden, Grant. "Myxoma virus expressing human interleukin-12 does not induce myxomatosis in European rabbits". Journal
of virology (2007): https://europepmc.org/articles/PMC2168987.
10.1128/JVI.01483-07
- McFadden, Grant. "Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin". Cancer
research (2007): https://europepmc.org/articles/PMC4380180.
10.1158/0008-5472.CAN-07-1214
- McFadden, Grant. "Strategies that modulate inflammasomes: insights from host-pathogen interactions". Seminars in immunopathology
(2007): https://doi.org/10.1007/s00281-007-0080-5.
10.1007/s00281-007-0080-5
- McFadden, Grant. "Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer". Expert opinion
on biological therapy (2007): https://doi.org/10.1517/14712598.7.9.1415.
10.1517/14712598.7.9.1415
- McFadden, Grant. "Tropism of Tanapox virus infection in primary human cells". Virology (2007): https://doi.org/10.1016/j.virol.2007.06.019.
10.1016/j.virol.2007.06.019
- McFadden, Grant. "BAFfled by poxviruses?". Cell host & microbe (2007): https://doi.org/10.1016/j.chom.2007.05.002.
10.1016/j.chom.2007.05.002
- McFadden, Grant. "Comparative genetic analysis of genomic DNA sequences of two human isolates of Tanapox virus". Virus
research (2007): https://doi.org/10.1016/j.virusres.2007.05.001.
10.1016/j.virusres.2007.05.001
- McFadden, Grant. "Identification of host range mutants of myxoma virus with altered oncolytic potential in human glioma cells".
Journal of neurovirology (2007): https://doi.org/10.1080/13550280701591526.
10.1080/13550280701591526
- McFadden, Grant. "Poxvirus cancer therapy". Recent patents on anti-infective drug discovery (2006): https://doi.org/10.2174/157489106778777592.
10.2174/157489106778777592
- McFadden, Grant. "Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain
that inhibits cellular TNFR1-induced cell death". Journal of virology (2006): https://europepmc.org/articles/PMC1563942.
10.1128/JVI.02449-05
- McFadden, Grant. "Variation in ligand binding specificities of a novel class of poxvirus-encoded tumor necrosis factor-binding
protein". The Journal of biological chemistry (2006): https://doi.org/10.1074/jbc.M604645200.
10.1074/jbc.m604645200
- McFadden, Grant. "Optimization of codon usage of poxvirus genes allows for improved transient expression in mammalian cells".
Virus genes (2006): https://europepmc.org/articles/PMC7089053.
10.1007/s11262-005-0035-7
- McFadden, Grant. "Prevention of chronic renal allograft rejection by SERP-1 protein". Transplantation (2006): https://doi.org/10.1097/01.tp.0000203141.02725.8a.
10.1097/01.tp.0000203141.02725.8a
- McFadden, Grant. "Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat
host range factor". Proceedings of the National Academy of Sciences of the United States of America (2006): https://europepmc.org/articles/PMC1450224.
10.1073/pnas.0509341103
- McFadden, Grant. "Anti-immunology: evasion of the host immune system by bacterial and viral pathogens". Cell (2006):
https://doi.org/10.1016/j.cell.2006.01.034.
10.1016/j.cell.2006.01.034
- McFadden, Grant. "Identification of myxomaviral serpin reactive site loop sequences that regulate innate immune responses".
The Journal of biological chemistry (2006): https://doi.org/10.1074/jbc.M509454200.
10.1074/jbc.m509454200
- McFadden, Grant. "Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria".
Journal of virology (2006): https://europepmc.org/articles/PMC1346952.
10.1128/JVI.80.3.1140-1151.2006
- Dai, E.; Viswanathan, K.; Yun, M.S.; Li, X.; Li, Y.L.; Togonu-Bickersteth, B.; Richardson, J.; et al. "Identification of myxomaviral
serpin reactive site loop sequences that regulate innate immune responses". Journal of Biological Chemistry 281 12
(2006): 8041-8050. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646373439&partnerID=MN8TOARS.
10.1074/jbc.M509454200
- Johnston, J.B.; Barrett, J.W.; Nazarian, S.H.; Goodwin, M.; Ricciuto, D.; Wang, G.; McFadden, G.. "A Poxvirus-Encoded Pyrin
Domain Protein Interacts with ASC-1 to Inhibit Host Inflammatory and Apoptotic Responses to Infection (DOI:10.1016/j.immuni.2005.10.003)".
Immunity 25 4 (2006): 687-687. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749509058&partnerID=MN8TOARS.
10.1016/j.immuni.2006.10.003
- McFadden, Grant. "Modulation of tumor necrosis factor by microbial pathogens". PLoS pathogens (2006): https://europepmc.org/articles/PMC1383482.
10.1371/journal.ppat.0020004
- Rahman, M.M.; Barrett, J.W.; Brouckaert, P.; McFadden, G.. "Variation in ligand binding specificities of a novel class of
poxvirus-encoded tumor necrosis factor-binding protein". Journal of Biological Chemistry 281 32 (2006): 22517-22526.
http://www.scopus.com/inward/record.url?eid=2-s2.0-33747371959&partnerID=MN8TOARS.
10.1074/jbc.M604645200
- Johnston, J.B.; Wang, G.; Barrett, J.W.; Nazarian, S.H.; Colwill, K.; Moran, M.; McFadden, G.. "Myxoma virus M-T5 protects
infected cells from the stress of cell cycle arrest through its interaction with host cell cullin-1". Journal of Virology
79 16 (2005): 10750-10763. http://www.scopus.com/inward/record.url?eid=2-s2.0-23244452458&partnerID=MN8TOARS.
10.1128/JVI.79.16.10750-10763.2005
- McFadden, Grant. "Myxoma virus M141R expresses a viral CD200 (vOX-2) that is responsible for down-regulation of macrophage
and T-cell activation in vivo". Journal of virology (2005): https://europepmc.org/articles/PMC1091733.
10.1128/JVI.79.10.6052-6067.2005
- McFadden, Grant. "Myxoma virus infection of primary human fibroblasts varies with cellular age and is regulated by host interferon
responses". Virology (2005): https://doi.org/10.1016/j.virol.2004.11.030.
10.1016/j.virol.2004.11.030
- McFadden, Grant. "Poxvirus tropism". Nature reviews. Microbiology (2005): https://europepmc.org/articles/PMC4382915.
10.1038/nrmicro1099
- McFadden, Grant. "A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic
responses to infection". Immunity (2005): https://doi.org/10.1016/j.immuni.2005.10.003.
10.1016/j.immuni.2005.10.003
- McFadden, Grant. "Expression profiling of herpesvirus and vaccinia virus proteins using a high-throughput baculovirus screening
system". Journal of proteome research (2005): https://doi.org/10.1021/pr050137u.
10.1021/pr050137u
- McFadden, Grant. "Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas".
Cancer research (2005): https://europepmc.org/articles/PMC4373463.
10.1158/0008-5472.CAN-05-1201
- McFadden, Grant. "Current Status for High Titre Poxvirus Stock Preparation in CEF Under Serum-Free Medium Conditions: Implication
for Vaccine Development". Cytotechnology (2005): https://europepmc.org/articles/PMC3449719.
10.1007/s10616-005-3795-y
- McFadden, Grant. "Gleevec casts a pox on poxviruses". Nature medicine (2005): https://doi.org/10.1038/nm0705-711.
10.1038/nm0705-711
- McFadden, Grant. "Myxoma virus M128L is expressed as a cell surface CD47-like virulence factor that contributes to the downregulation
of macrophage activation in vivo". Virology (2005): https://doi.org/10.1016/j.virol.2005.03.037.
10.1016/j.virol.2005.03.037
- McFadden, Grant. "The 'supervirus'? Lessons from IL-4-expressing poxviruses". Trends in immunology (2005): https://doi.org/10.1016/j.it.2005.04.001.
10.1016/j.it.2005.04.001
- Seet, B.T.; McCaughan, C.A.; Handel, T.M.; Mercer, A.; Brunetti, C.; McFadden, G.; Fleming, S.B.. "Erratum: Analysis of an
orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors (Proceedings of
the National Academy of Sciences of the United States of America (December 9, 2003) 110, 25 (15137-15142))". Proceedings
of the National Academy of Sciences of the United States of America 101 14 (2004): 5180-5180. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842687043&partnerID=MN8TOARS.
- Seet, B.T.; McFadden, G.. "Interaction analysis of viral cytokine-binding proteins using surface plasmon resonance.". Methods
in molecular biology (Clifton, N.J.) 269 (2004): 219-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-4043156895&partnerID=MN8TOARS.
- McFadden, Grant. "Smallpox: an ancient disease enters the modern era of virogenomics". Proceedings of the National Academy
of Sciences of the United States of America (2004): https://europepmc.org/articles/PMC524071.
10.1073/pnas.0406207101
- McFadden, Grant. "Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier". Nature
immunology (2004): https://doi.org/10.1038/ni1132.
10.1038/ni1132
- McFadden, Grant. "Technical knockout: understanding poxvirus pathogenesis by selectively deleting viral immunomodulatory genes".
Cellular microbiology (2004): https://doi.org/10.1111/j.1462-5822.2004.00423.x.
10.1111/j.1462-5822.2004.00423.x
- McFadden, Grant. "Secreted immunomodulatory viral proteins as novel biotherapeutics". Journal of immunology (Baltimore,
Md. : 1950) (2004): https://doi.org/10.4049/jimmunol.173.8.4765.
10.4049/jimmunol.173.8.4765
- McFadden, Grant. "Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak". Journal of virology
(2004): https://europepmc.org/articles/PMC421673.
10.1128/JVI.78.13.7097-7111.2004
- McFadden, Grant. "Interaction analysis of viral cytokine-binding proteins using surface plasmon resonance". Methods in
molecular biology (Clifton, N.J.) (2004): https://doi.org/10.1385/1-59259-789-0:219.
10.1385/1-59259-789-0:219
- McFadden, Grant. "Viral chemokine-binding proteins inhibit inflammatory responses and aortic allograft transplant vasculopathy
in rat models". Transplantation (2004): https://doi.org/10.1097/01.tp.0000131173.52424.84.
10.1097/01.tp.0000131173.52424.84
- Liu, L.; Dai, E.; Miller, L.; Seet, B.; Lalani, A.; Macauley, C.; Li, X.; et al. "Viral chemokine-binding proteins inhibit
inflammatory responses and aortic allograft transplant vasculopathy in rat models". Transplantation 77 11 (2004): 1652-1660.
http://www.scopus.com/inward/record.url?eid=2-s2.0-2942633274&partnerID=MN8TOARS.
10.1097/01.TP.0000131173.52424.84
- McFadden, Grant. "Poxviruses and immune evasion". Annual review of immunology (2003): https://doi.org/10.1146/annurev.immunol.21.120601.141049.
10.1146/annurev.immunol.21.120601.141049
- McFadden, Grant. "Complete genomic sequence and comparative analysis of the tumorigenic poxvirus Yaba monkey tumor virus".
Journal of Virology (2003): https://europepmc.org/articles/PMC296094.
10.1128/JVI.77.24.13335-13347.2003
- McFadden, Grant. "Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus
viroceptors". Proceedings of the National Academy of Sciences of the United States of America (2003): https://europepmc.org/articles/PMC299921.
10.1073/pnas.2336648100
- McFadden, Grant. "Poxvirus immunomodulatory strategies: current perspectives". Journal of virology (2003): https://europepmc.org/articles/PMC155018.
10.1128/JVI.77.11.6093-6100.2003
- McFadden, Grant. "Chemokine-binding viral protein M-T7 prevents chronic rejection in rat renal allografts". Transplantation
(2003): https://doi.org/10.1097/01.TP.0000061604.57432.E3.
10.1097/01.tp.0000061604.57432.e3
- McFadden, Grant. "A secreted high-affinity inhibitor of human TNF from Tanapox virus". Proceedings of the National Academy
of Sciences of the United States of America (2003): https://europepmc.org/articles/PMC153641.
10.1073/pnas.0737244100
- McFadden, Grant. "Role of the serine-threonine kinase PAK-1 in myxoma virus replication". Journal of virology (2003):
https://europepmc.org/articles/PMC154029.
10.1128/JVI.77.10.5877-5888.2003
- Dai, E.; Guan, H.; Liu, L.; Little, S.; McFadden, G.; Vaziri, S.; Cao, H.; et al. "Serp-1, a viral anti-inflammatory serpin,
regulates cellular serine proteinase and serpin responses to vascular injury". Journal of Biological Chemistry 278
20 (2003): 18563-18572. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038381452&partnerID=MN8TOARS.
10.1074/jbc.M209683200
- McFadden, Grant. "Serp-1, a viral anti-inflammatory serpin, regulates cellular serine proteinase and serpin responses to vascular
injury". The Journal of biological chemistry (2003): https://doi.org/10.1074/jbc.M209683200.
10.1074/jbc.m209683200
- McFadden, Grant. "The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization
and lysosomal destruction of CD4". Journal of virology (2003): https://europepmc.org/articles/PMC140772.
10.1128/JVI.77.2.1427-1440.2003
- Bédard, E.L.R.; Kim, P.; Jiang, J.; Parry, N.; Liu, L.; Wang, H.; Garcia, B.; et al. "Chemokine-binding viral protein M-T7
prevents chronic rejection in rat renal allografts". Transplantation 76 1 (2003): 249-252. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037962278&partnerID=MN8TOARS.
10.1097/01.TP.0000061604.57432.E3
- McFadden, Grant. "Smallpox: anything to declare?". Nature reviews. Immunology (2002): https://doi.org/10.1038/nri845.
10.1038/nri845
- McFadden, Grant. "Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes".
American journal of physiology. Heart and circulatory physiology (2002): http://intl-ajpheart.physiology.org/cgi/content/full/282/4/H1216.
10.1152/ajpheart.00780.2001
- McFadden, Grant. "Leporipoxvirus Cu-Zn superoxide dismutase homologs inhibit cellular superoxide dismutase, but are not essential
for virus replication or virulence". Virology (2002): https://doi.org/10.1006/viro.2002.1383.
10.1006/viro.2002.1383
- McFadden, Grant. "Immune responses to myxoma virus". Viral immunology (2002): https://doi.org/10.1089/08828240260066198.
10.1089/08828240260066198
- McFadden, Grant. "Characterization of a pan-species reactive monoclonal antibody specific for a cell surface epitope which
could serve as a marker for human monocytic and megakaryocytic differentiation". Hybridoma and hybridomics (2002):
https://doi.org/10.1089/153685902321043972.
10.1089/153685902321043972
- McFadden, Grant. "Characterization of a monoclonal antibody specific for a novel primate cell surface marker with distinct
biochemical properties on human erythroleukemia and myeloid cell lines". Hybridoma and hybridomics (2002): https://doi.org/10.1089/153685902760213886.
10.1089/153685902760213886
- McFadden, Grant. "The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability
transition pore". The Journal of experimental medicine (2002): https://europepmc.org/articles/PMC2194110.
10.1084/jem.20011247
- McFadden, Grant. "Viral chemokine-binding proteins". Journal of leukocyte biology (2002): http://www.jleukbio.org/cgi/content/full/72/1/24.
- McFadden, Grant. "Poxviruses and apoptosis: a time to die". Current opinion in microbiology (2002): https://doi.org/10.1016/s1369-5274(02)00340-5.
10.1016/s1369-5274(02)00340-5
- McFadden, Grant. "Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitor". Proceedings
of the National Academy of Sciences of the United States of America (2001): https://europepmc.org/articles/PMC55364.
10.1073/pnas.171069398
- McFadden, Grant. "Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action".
Journal of virology (2000): https://europepmc.org/articles/PMC112190.
10.1128/jvi.74.15.6741-6747.2000
- McFadden, Grant. "M11L: a novel mitochondria-localized protein of myxoma virus that blocks apoptosis of infected leukocytes".
The Journal of experimental medicine (2000): https://europepmc.org/articles/PMC2213443.
10.1084/jem.191.9.1487
- McFadden, Grant. "The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury".
The Journal of clinical investigation (2000): https://europepmc.org/articles/PMC300852.
10.1172/jci8934
- McFadden, Grant. "Mechanism of replication of phi x174 single-stranded DNA. IX. Requirement for the Escherichia coli dnaG
protein". Journal of virology (1974): https://europepmc.org/articles/PMC355621.
|
