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Sandra Aguiar graduated in Applied Chemistry - Biotechnology in 2003 at Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa during which she enrolled a research project at the University of Nottingham as an Erasmus student. She then completed a Master’s in Clinical Microbiology and a PhD in Microbiology at the iMM/FM-ULisboa. Following her PhD, she secured a FCT postdoc fellowship in 2011 to continue the research on S. pneumoniae biology and impact of vaccines. During this period, she was involved in teaching Microbiology classes at the Faculty of Medicine as an invited assistant Professor (2005-2015). In 2015, she was awarded a new FCT post-doctoral grant at the antibody Engineering Lab supervised by Professor Frederico Aires da Silva (CIISA-FMV) to develop new therapeutic strategies. By combining the groups research in antibody-based therapies with her background in bacterial infections she started a new research line in targeted therapies for bacterial infections which has enrolled two master and one PhD student and the first study publications, in which she is the corresponding author, have recently been submitted (Ferreira et Al, Pharmaceutics, 2021). To promote international and national collaborations and research interdisciplinarity, she integrated the brain infections ESCMID study group and have established a collaboration with the ExtremoChem biotech company. She also continuously attended national and international courses, such as the “Host-pathogen interaction course” at the Institute Pasteur in France and the EMBL-training “Proteomics Bioinformatics” in Cambridge, UK. Together with scientific research, it is one of her core intentions to maximize the value of publicly funded research to benefit society. To achieve the translation and commercialization of scientific discoveries, she pursued two entrepreneurship courses (StartHealth-UL and CoHitec) in which was attributed a second prize for best start-up project by the ULisboa and attended a Management postgraduation course by Católica Lisbon School of Business and Economics. With 16 years of experience, she has published 29 scientific publications with 438 citations and an h-index of 11, of which 1 patent, 2 book chapters and 12 journal articles (all Q1) in the last 5 effective years. Furthermore, since 2015 she has contributed to the funding of 8 research projects, FCT (N=3), Gilead Génese (N=2) and CIISA-FVM (N=3), being principal investigator in the later.
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Identificação

Identificação pessoal

Nome completo
Sandra Aguiar
Data de nascimento
1980/09/24
Género
Feminino

Nomes de citação

  • Aguiar, Sandra I

Identificadores de autor

Ciência ID
8E10-C536-8517
ORCID iD
0000-0002-3041-383X
Researcher Id
A-3500-2009

Endereços de correio eletrónico

  • saguiar@fmv.ulisboa.pt (Profissional)

Moradas

  • Faculdade de Medicina Veterinária - Universidade de Lisboa. Av. Universidade Técnica, 1300-477, Lisboa, Lisboa, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica
  • Ciências Naturais - Ciências Biológicas - Microbiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Formação
Grau Classificação
2015/01/01 - 2019/01/31
Concluído
 Development of an immunoliposomal therapy for treatment of pneumococcal meningitis (SFRH/BPD/100522/2014) (Pós-doutoramento)
Especialização em Biotechnology
CIISA-FMV Universidade de lisboa, Portugal

Instituto de Medicina Molecular, Portugal
2015
Concluído
 General Management Program (PGG) (Pós-Graduação)
Universidade Católica Portuguesa Católica Porto Business School, Portugal
 Very Good
2011/07/01 - 2014/12/31
Concluído
 Molecular characterization of Streptococcus pneumoniae responsible for invasive disease in the pediatric setting (SFRH/BPD/78376/2011) (Pós-doutoramento)
Especialização em Health Sciences -Microbiology
Instituto de Medicina Molecular, Portugal
2006/10/01 - 2011/07/01
Concluído
 Molecular epidemiology of Streptococcus pneumoniae: impact of PCV7 in the pneumococcal population responsible for invasive pediatric infections (SFRH/BD/27518/2006) (Doutoramento)
Especialização em Health sciences - Microbiology
Universidade de Lisboa Faculdade de Medicina, Portugal
"Molecular epidemiology of Streptococcus pneumoniae: Impact of PCV7 in the pneumococcal population responsible for invasive pediatric infections" (TESE/DISSERTAÇÃO)
 Approved with distinction and Honours
2004/01/03 - 2006/06/26
Concluído
 Clinical Microbiology (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
"Phenotypic and genotypic characterization of Streptococcus pneumoniae responsible for infections in pre-school children" (TESE/DISSERTAÇÃO)
 Approved with distinction and Honours
1998/09 - 2003/12/02
Concluído
 Applied Chemistry (Licenciatura)
Especialização em Biotecnology
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
""Supercritical impregnation of catheters and aerogel with metal nanoparticles- University of Nottingham" "Analysis of mutations in Wilm's Tumours-Universidade Nova de Lisboa - Faculdade de Ciências e Tecnologia" " (TESE/DISSERTAÇÃO)
 15/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/02/01 - 2022/01/31 Investigador Contratado (Investigação) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2015/01/01 - 2019/01/31 Pós-doutorado (Investigação) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2011/07/01 - 2014/12/31 Pós-doutorado (Investigação) Instituto de Medicina Molecular, Portugal
2004/06/01 - 2011/05/31 Investigador (Investigação) Instituto de Medicina Molecular, Portugal
2003/03/01 - 2003/10/31 Estagiário de Investigação (Investigação) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2002/06/01 - 2002/09/06 Estagiário de Investigação (Investigação) University of Nottingham School of Chemistry, Reino Unido
University of Nottingham School of Chemistry, Reino Unido
(...)

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/09/01 - Atual Professor Auxiliar Convidado (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2005/03/01 - 2015/02/28 Assistente Convidado (Docente Universitário) Universidade de Lisboa Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2015/12/01 - 2019/01/31 Development of immunoliposomal therapy for treatment of Pneumococcal meningitis.
SFRH/BPD/100522/2014
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/07/01 - 2014/12/31 Molecular characterization of Streptococcus pneumoniae responsible for invasive disease in the pediatric setting
SFRH/BPD/78376/2011
Bolseiro de Pós-Doutoramento
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluído
2006/10/01 - 2010/09/30 Molecular epidemiology of streptococcus pneumoniae: impact of PCV7 in the pneumococcal population responsible for invasive pediatric infections
SFRH/BD/27518/2006
Bolseiro de Doutoramento
Instituto de Medicina Molecular, Portugal

Universidade de Lisboa Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2020/01/02 - 2022/12/31 LYMPHOTARGET - Desenvolvimento de imunolipossomas para o tratamento direcionado do Linfoma não-Hodgkin
PGG/050/2019
Investigador
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

CIISA-FMV Universidade de lisboa, Portugal
Gilead GÉNESE -2016
Em curso
2021/01/01 - 2021/12/30 Staphylococcus targeting liposomes: a novel drug delivery strategy for MRSA infections
INOV20Set – 04
Investigador responsável
CIISA-FMV Universidade de lisboa, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/06/14 - 2021/06/13 Development of a novel class of antibody-drug conjugates molecules for cancer treatment
PTDC/BTM-SAL/32085/2017
Investigador
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2016/05/01 - 2019/10/31 Alzheimer3D: Trifunctional Conjugates for the Selective Drug Delivery in Alzheimer’s Disease
PTDC/QEQ-MED/5512/2014
Investigador
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e Tecnologia - FCT
Em curso
2016/05/01 - 2019/04/30 Overcoming the Brain Drug Delivery Bottleneck: Development of single domain antibodies for brain targeting and drug delivery across the Blood-Brain Barrier.
PTDC/BBB-BIO/0508/2014
Investigador
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Em curso
2018/04/01 - 2019/03/31 In vitro efficacy of a brain targeted antibiotic encapsulated liposome for treatment of bacterial meningitis.
UID/CVT/00276/2014
Investigador responsável
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal

Fundação para a Ciência e a Tecnologia
Concluído
2017 - 2018/12 Development of anti-gp120/gp41 bispecific antibodies for HIV infection treatment
PGG/015/2016
Investigador
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Gilead GÉNESE -2016
Em curso
2017/01 - 2017/12 Development of a new immunoliposome drug delivery system for treatment of pneumococcal meningitis
UID/CVT/00276/2019
Investigador responsável
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 CIISA-FMV Universidade de lisboa

Fundação para a Ciência e a Tecnologia
Concluído
2012 - 2015 Besieged by conjugate vaccination: changes in the pneumococcal population and their genomic consequences
PTDC/DTP-EPI/1759/2012
Investigador
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluído
2007 - 2010 Implications for therapy and disease presentation of the changes triggered by the use of the pneumococcal 7-valent conjugate vaccine
PIC/IC/83065/2007
Investigador
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluído
2006 - 2009 Population and genomic consequences of vaccination against Streptococcus pneumoniae
PTDC/SAU-ESA/64888/2006
Investigador
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluído

Outro

Designação Financiadores
2020/12/01 - Atual Evaluation of the stability of DNA and RNA in the presence of organic solvents
FMV_extremoChem_2
Investigador responsável
CIISA-FMV Universidade de lisboa, Portugal

Extremochem Lda, Portugal
Em curso
2019/02/01 - Atual Vector B2B
Vector B2B
Investigador
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Em curso
Produções

Publicações

Artigo em revista
  1. Aguiar, Sandra I. "Diazaborines Are a Versatile Platform to Develop ROS-Responsive Antibody Drug Conjugates**". Angewandte Chemie International Edition (2021): http://dx.doi.org/10.1002/anie.202109835.
    10.1002/anie.202109835
  2. Aguiar, Sandra I. "Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening". Pharmaceutics 13 10 (2021): 1598-1598. http://dx.doi.org/10.3390/pharmaceutics13101598.
    10.3390/pharmaceutics13101598
  3. Aguiar, Sandra I. "Chemokine-Directed Tumor Microenvironment Modulation in Cancer Immunotherapy". International Journal of Molecular Sciences 22 18 (2021): 9804-9804. http://dx.doi.org/10.3390/ijms22189804.
    10.3390/ijms22189804
  4. Dias JNR; André AS; Aguiar SI; Gil S; Tavares L; Aires-da-Silva F. "Immunotherapeutic Strategies for Canine Lymphoma: Changing the Odds Against Non-Hodgkin Lymphoma.". Frontiers in veterinary science (2021): http://europepmc.org/abstract/med/34513964.
    10.3389/fvets.2021.621758
  5. Ferreira, Magda; Ogren, Maria; Dias, Joana N. R.; Silva, Marta; Gil, Solange; Tavares, Luís; Aires-da-Silva, Frederico; Gaspar, Maria Manuela; Aguiar, Sandra Isabel. "Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance". Molecules 26 7 (2021): 2047. http://dx.doi.org/10.3390/molecules26072047.
    10.3390/molecules26072047
  6. Ferreira, Magda; Pinto, Sandra N.; Aires-da-Silva, Frederico; Bettencourt, Ana; Aguiar*, Sandra I.; Gaspar*, Maria Manuela. "Liposomes as a Nanoplatform to Improve the Delivery of Antibiotics into Staphylococcus aureus Biofilms". Pharmaceutics 13 3 (2021): 321. http://dx.doi.org/10.3390/pharmaceutics13030321.
    Acesso aberto • 10.3390/pharmaceutics13030321
  7. Aguiar, Sandra I; André, A.S.; Martins, D; Dias, J.N.R.; Gano, L.; Galamba, J.; Tavares, L.; et al. "Highly specific BBB transmigrating single domain antibodies selected by an in vivo phage display screening". (2021):
    Submetido
  8. Singh, Sumnima; Thompson, Jessica A.; Yilmaz, Bahtiyar; Li, Hai; Weis, Sebastian; Sobral, Daniel; Truglio, Mauro; et al. "Loss of a-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis". Cell Host & Microbe (2021): http://dx.doi.org/10.1016/j.chom.2020.12.017.
    Aceite para publicação • 10.1016/j.chom.2020.12.017
  9. Alves, F.; Prata, S.; Nunes, T.; Gomes, J.; Aguiar, S.; Aires da Silva, F.; Tavares, L.; Almeida, V.; Gil, S.. "Canine parvovirus: a predicting canine model for sepsis". BMC Veterinary Research 16 1 (2020): http://dx.doi.org/10.1186/s12917-020-02417-0.
    Publicado • 10.1186/s12917-020-02417-0
  10. Magda Ferreira; Sandra Aguiar; Ana Bettencourt; Maria Manuela Gaspar. "Lipid-based nanosystems for targeting bone implant-associated infections: current approaches and future endeavors". Drug Delivery and Translational Research (2020): https://doi.org/10.1007/s13346-020-00791-8.
    10.1007/s13346-020-00791-8
  11. Brito, M.J.; Silva-Costa, C.; Aguiar, S.; Lopes, J.P.; Ramirez, M.; Melo-Cristino, J.. "The increasing importance of non-culture methods in diagnosis and serotyping of invasive pediatric pneumococcal infections revealed the continuous dominance of vaccine serotypes in the era of PCV13 vaccination". International Journal of Infectious Diseases 79 (2019): 132. http://dx.doi.org/10.1016/j.ijid.2018.11.323.
    10.1016/j.ijid.2018.11.323
  12. Aguiar, Sandra I. "The increasing importance of non-culture methods in diagnosis and serotyping of invasive pediatric pneumococcal infections revealed the continuous dominance of vaccine serotypes in the era of PCV13 vaccination". International Journal of Infectious Diseases (2019):
    https://doi.org/10.1016/j.ijid.2018.11.323
  13. Silva-Costa, Catarina; Brito, Maria J.; Aguiar, Sandra I.; Lopes, Joana P.; Ramirez, Mário; Melo-Cristino, José. "Dominance of vaccine serotypes in pediatric invasive pneumococcal infections in Portugal (2012–2015)". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-018-36799-x.
    Publicado • 10.1038/s41598-018-36799-x
  14. Dias, Joana N. R.; André, Ana S.; Aguiar, Sandra I.; Ministro, Joana; Oliveira, Joana; Peleteiro, Maria C.; Rütgen, Barbara; et al. "Establishment of a bioluminescent canine B-cell lymphoma xenograft model for monitoring tumor progression and treatment response in preclinical studies". PLOS ONE 13 12 (2018): e0208147. http://dx.doi.org/10.1371/journal.pone.0208147.
    Publicado • 10.1371/journal.pone.0208147
  15. Silva-Costa, Catarina; Brito, Maria João; Pinho, Marcos D.; Friães, Ana; Aguiar, Sandra I.; Ramirez, M.; Melo-Cristino, Jose. "Pediatric Complicated Pneumonia Caused by Streptococcus pneumoniae Serotype 3 in 13-Valent Pneumococcal Conjugate Vaccinees, Portugal, 2010–2015". Emerging Infectious Diseases 24 7 (2018): 1307-1314. http://dx.doi.org/10.3201/eid2407.180029.
    Publicado • 10.3201/eid2407.180029
  16. Dias, Joana N.R.; Aguiar, Sandra I.; Pereira, Diane M.; André, Ana S.; Gano, Lurdes; Correia, João D.G.; Carrapiço, Belmira; et al. "The histone deacetylase inhibitor panobinostat is a potent antitumor agent in canine diffuse large B-cell lymphoma". Oncotarget 9 47 (2018): http://dx.doi.org/10.18632/oncotarget.25580.
    Publicado • 10.18632/oncotarget.25580
  17. Neves, Vera; Aires-da-Silva, Frederico; Morais, Maurício; Gano, Lurdes; Ribeiro, Elisabete; Pinto, Antónia; Aguiar, Sandra; et al. "Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism". ACS Chemical Biology 12 5 (2017): 1257-1268. http://dx.doi.org/10.1021/acschembio.7b00087.
    Publicado • 10.1021/acschembio.7b00087
  18. Diamantino-Miranda, Jorge; Aguiar, Sandra Isabel; Carrico, Joao Andre; Melo-Cristino, Jose; Ramirez, Mario. "Clonal and serotype dynamics of serogroup 6 isolates causing invasive pneumococcal disease in Portugal: 1999-2012". Plos One 12 2 (2017): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000396161200021&KeyUID=WOS:000396161200021.
    10.1371/journal.pone.0170354
  19. Aguiar, S I; Brito, M J; Horácio, A N; Lopes, J P; Ramirez, M; Melo-Cristino, J; on behalf of the Portuguese Group f, Collective. "Decreasing incidence and changes in serotype distribution of invasive pneumococcal disease in persons aged under 18 years since introduction of 10-valent and 13-valent conjugate vaccines in Portugal, July 2008 to June 2012". Eurosurveillance 19 12 (2014): http://dx.doi.org/10.2807/1560-7917.es2014.19.12.20750.
    Acesso aberto • 10.2807/1560-7917.es2014.19.12.20750
  20. Aguiar SI; Brito MJ; Horacio AN; Lopes JP; Ramirez M; Melo-Cristino J; Portuguese Group for the Study of Streptococcal Infections; Portuguese Study Group of Invasive Pneumococcal Disease of the Paediatric Infectious Disease Society. "Decreasing incidence and changes in serotype distribution of invasive pneumococcal disease in persons aged under 18 years since introduction of 10-valent and 13-valent conjugate vaccines in Portugal, July 2008 to June 2012.". (2014): http://europepmc.org/abstract/med/24698140.
  21. Horácio, A.N.; Diamantino-Miranda, J.; Aguiar, S.I.; Ramirez, M.; Melo-Cristino, J.. "The Majority of Adult Pneumococcal Invasive Infections in Portugal Are Still Potentially Vaccine Preventable in Spite of Significant Declines of Serotypes 1 and 5". PLoS ONE 8 9 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84884197325&partnerID=MN8TOARS.
    Publicado • 10.1371/journal.pone.0073704
  22. Costa, A.; Afonso, J.; Osório, C.; Gomes, A.L.; Caiado, F.; Valente, J.; Aguiar, S.I.; et al. "MiR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells". Journal of Hematology and Oncology 6 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887928259&partnerID=MN8TOARS.
    Publicado • 10.1186/1756-8722-6-87
  23. Aguiar, Sandra I.; Melo-Cristino, Jose; Ramirez, Mario. "Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease". Vaccine 30 37 (2012): 5487-5490. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307697800007&KeyUID=WOS:000307697800007.
    10.1016/j.vaccine.2012.06.062
  24. Horácio, A.N.; Diamantino-Miranda, J.; Aguiar, S.I.; Ramirez, M.; Melo-Cristino, J.. "Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infections". Vaccine 30 2 (2012): 218-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-84355161924&partnerID=MN8TOARS.
    Publicado • 10.1016/j.vaccine.2011.11.022
  25. Sa-Leao, Raquel; Pinto, Francisco; Aguiar, Sandra; Nunes, Sonia; Carrico, Joao A.; Frazao, Nelson; Goncalves-Sousa, Natacha; et al. "Analysis of Invasiveness of Pneumococcal Serotypes and Clones Circulating in Portugal before Widespread Use of Conjugate Vaccines Reveals Heterogeneous Behavior of Clones Expressing the Same Serotype". Journal of Clinical Microbiology 49 4 (2011): 1369-1375. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000289080600028&KeyUID=WOS:000289080600028.
    Publicado • 10.1128/JCM.01763-10
  26. Aguiar, S.I.; Brito, M.J.; Gonçalo-Marques, J.; Melo-Cristino, J.; Ramirez, M.. "Serotypes 1, 7F and 19A became the leading causes of pediatric invasive pneumococcal infections in Portugal after 7 years of heptavalent conjugate vaccine use". Vaccine 28 32 (2010): 5167-5173. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954953848&partnerID=MN8TOARS.
    Publicado • 10.1016/j.vaccine.2010.06.008
  27. Aguiar, Sandra I.; Pinto, Francisco R.; Nunes, Sonia; Serrano, Isa; Melo-Cristino, Jose; Sa-Leao, Raquel; Ramirez, Mario; de Lencastre, Herminia. "Denmark(14)-230 Clone as an Increasing Cause of Pneumococcal Infection in Portugal within a Background of Diverse Serotype 19A Lineages". Journal of Clinical Microbiology 48 1 (2010): 101-108. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000276151500013&KeyUID=WOS:000276151500013.
    Publicado • 10.1128/JCM.00665-09
  28. AGUIAR, SI; SERRANO, I; PINTO, FR; et al.. "Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine". CLINICAL MICROBIOLOGY AND INFECTION 14 9 (2008): 835-843. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000258441400004&KeyUID=WOS:000258441400004.
    10.1111/j.1469-0691.2008.02031.x
  29. AGUIAR, SI; SERRANO, I; PINTO, FR; et al.. "The presence of the pilus locus is a clonal property among pneumococcal invasive isolates". BMC MICROBIOLOGY 8 (2008): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000254367700001&KeyUID=WOS:000254367700001.
    Publicado • 10.1186/1471-2180-8-41
  30. Pinto, F.R.; Aguiar, S.I.; Melo-Cristino, J.; Ramirez, M.. "Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays". BMC Genomics 9 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-44649164484&partnerID=MN8TOARS.
    Publicado • 10.1186/1471-2164-9-230
  31. AGUIAR, SI; FRIAS, MJ; SANTOS, L; et al.. "Emergence of optochin resistance among Streptococcus pneumoniae in Portugal". MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE 12 4 (2006): 239-245. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000243439200003&KeyUID=WOS:000243439200003.
    Publicado • 10.1089/mdr.2006.12.239
  32. Figueiredo, T.A.; Aguiar, S.I.; Melo-Cristino, J.; Ramirez, M.. "DNA methylase activity as a marker for the presence of a family of phage-like elements conferring efflux-mediated macrolide resistance in streptococci". Antimicrobial Agents and Chemotherapy 50 11 (2006): 3689-3694. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750587170&partnerID=MN8TOARS.
    Publicado • 10.1128/AAC.00782-06
Capítulo de livro
  1. Aires-da-Silva, F.; Dias, J.; Aguiar, S. I.; Marques, F.; André, A.; Gil, S.; Tavares, L.. "Novel Diagnostic and Therapeutic Immunologic Strategies to Overcome Infectious, Oncologic and Neurodegenerative Disorders". In Advances in Animal Health, Medicine and Production, 436-459. Springer International Publishing, 2020.
    Publicado • 10.1007/978-3-030-61981-7_24
  2. Aguiar, Sandra; Dias, Joana; Manuel, Ana M.; Russo, Roberto; Gois, Pedro M.P.; da Silva, Frederico A.; Goncalves, Joao. "Chimeric Small Antibody Fragments as Strategy to Deliver Therapeutic Payloads". In Advances in Protein Chemistry and Structural Biology, 143-182. Elsevier, 2018.
    Publicado • 10.1016/bs.apcsb.2018.03.002
Poster em conferência
  1. Ferreira, Magda; Ribeiro, I.A.C; Aires-da-Silva, Frederico; Aguiar, Sandra I; Gaspar, Maria Manuela. "Antibiotic-loaded Liposomes with High Potential Towards S. aureus Infections". Trabalho apresentado em XIII Spanish-Portuguese Conference on Controlled Drug Delivery, Santiago de Compostela, Spain, 2020.
  2. Aguiar, Sandra I; Silva, Marta; Martins, Diana; André, Ana S.; Neves, Vera; Dias, Joana NR; Carrapiço, Belmira; et al. "Overcoming the BBB: in vivo selection of single domain antibodies for brain targeting and drug delivery". Trabalho apresentado em 11th Annual PEGS EUROPE 18-22th November 2019, Lisbon, Portugal, 2019.
  3. Ferreira, Magda; Pinto, Sandra; Aires-da-Silva, Frederico; António, Almeida; Aguiar, Sandra I; Bettencourt, Ana; Gaspar, Maria Manuela. "Antibiotic-lipid Based Nanosystems as a Tool for Staphylococcus aureus Associated Bone Infections". Trabalho apresentado em 38th Annual Meeting of the European Bone and Joint Infection Society, European Bone and Joint Infection Society (EBJIS), Antwerp, Belgium;, 2019.
  4. Ferreira, Magda; Pinto, Sandra; Ana F Bettencourt; Aguiar, Sandra I; Gaspar, Maria Manuela. "Liposomes as a Tool to Improve Antibacterial Effect of Antibiotics Towards S. aureus Infections". Trabalho apresentado em 6th International Symposium on Phospholipids in Pharmaceutical Research – Phospholipid Research Center, Heidelberg, Germany;, 2019.
  5. Ferreira, Magda; Pinto, Sandra; Ribeiro, I.A.; Aires-da-Silva, Frederico; Almeida, António; Bettencourt, Ana; Aguiar, Sandra I; Gaspar, Maria Manuela. "Antibiotic Liposomal Nanoformulations as a Tool to Inhibit Mature Staphylococcus aureus Biofilms". Trabalho apresentado em 11th iMed.ULisboa and 3rd i3du Postgraduate Students Meeting, Faculdade de Farmácia da Universidade de Lisboa (FFUL);, 2019.
  6. Aguiar, Sandra I; Gaspar, M.M.; André, A.S.; Martins, D; Ferreira, M; Carvalheiro, M; Neves, V.; et al. "sdAb-immunoliposomes for brain targeting and drug delivery". Trabalho apresentado em Antibody Engineering & Therapeutics, SanDiego, USA, 2018.
  7. Aguiar, Sandra I; Martins, D; André, A.S.; Neves, V.; Dias, J.N.R.; Carrapiço, B; Gano, L.; et al. "In vivo phage display selections for development of novel blood-brain barrier crossing single-domain antibodies". Trabalho apresentado em 11th Annual PEGS EUROPE, 2018.
  8. Rico, I; Dias, J.N.R.; Aguiar, SI; Gaspar, MM; Gil, S.; Aires da Silva, F.. "Development and optimization of liposomes encapsulated with potent cytotoxic compounds for immunotherapy". Trabalho apresentado em CIISA Congress 2018, 2018.
  9. Silva-Costa, C.; Brito, M J; Pinho, M.D.; Friães, A.; Aguiar, S.I.; Ramirez, M.; Melo-Cristino, J.. "SEROTYPE 3 IS THE LEADING CAUSE OF COMPLICATED PEDIATRIC PNEUMOCOCCAL PNEUMONIA IN PORTUGAL EVEN AMONG PCV13 VACCINATED CHILDREN (2010-2015)". Trabalho apresentado em 11th International symposium on pneumococci and pneumococcal diseases, Melbourne, Australia, 2018.
  10. Silva-Costa, C.; Horácio, A.N.; Aguiar, S.I.; Lopes, JP; Brito, M J; Ramirez, M.; Melo-Cristino, J.. "PERSISTENCE OF PCV7 AND PCV13 SEROTYPES IN PEDIATRIC INVASIVE PNEUMOCOCCAL DISEASE IN PORTUGAL AFTER MORE THAN A DECADE OF VACCINE USE". Trabalho apresentado em 11th International Symposium on Pneumococci and Pneumococcal Diseases, Melbourne, Australia, 2018.
  11. Aguiar, S.I.; Gaspar, M.M.; André, A.S.; Carvalheiro, M; Neves, V.; Coelho, S.; Dias, J.N.R.; et al. "Immunoliposomes for brain targeting and drug delivery". Trabalho apresentado em XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  12. Silva-Costa, C.; Horácio, A.N.; Aguiar, S.I.; Lopes, J P; Brito, M.J.; Ramirez, M.; Melo-Cristino, J. "Pediatric invasive pneumococcal disease in Portugal: changing epidemiology (2012-2016)". Trabalho apresentado em MicroBioTec'17 - Porto, Portugal, 2017.
  13. Dias, J.N.R.; Aguiar, S.I.; Pereira, DM; André, Ana S.; Gano, L.; Correia JDG; Carrapiço, B; et al. "In vitro and in vivo antitumor properties of histone deacetylase inhibitors in canine diffuse large B-cell lymphoma". Trabalho apresentado em Microbiotec 17', 2017.
  14. Prata, S; Aguiar, SI; Gomes, J.; Almeida, V.; Bexiga, R.; Tavares, L.; Aires da Silva, F.. "Canine model for sepsis: a contribution to the classification and stratification of septic patients". Trabalho apresentado em Microbiotec'17, 2017.
  15. Silva-Costa, C.; Horácio, A.N.; Aguiar, S.I.; Lopes JP; Brito, M.J.; Ramirez, M.; Melo-Cristino, J.. "PCV13 serotypes are still important causes of pediatric invasive pneumococcal disease in Portugal after more than a decade of conjugate vaccine". Trabalho apresentado em International Congress of Chemotherapy and Infection (ICC 2017). Taipei, Taiwan,, 2017.
  16. Silva-Costa, C.; Aguiar, S.I.; Pinho, M.D.; Friães, A.; Ramirez, M.; Melo-Cristino, J.. "Serotype distribution among Streptococcus pneumoniae isolates causing complicated pneumonia in children in Portugal (2010-2015)". Trabalho apresentado em 27th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria, 2017.
  17. Silva-Costa, C.; Aguiar, S.I.; Pinho, M.D.; Friães, A.; Ramirez, M.; Melo-Cristino, J.. "High prevalence of serotype 3 in pneumococcal isolates causing complicated pneumonia and empyema in Portugal (2010-2015)". Trabalho apresentado em International Meeting on Emerging Diseases and Surveillance (IMED 2016). Viena, Austria, 2016.
  18. Dias, J.N.R.; Gil, S.; Aguiar, S.I.; Oliveira, S.; Carrapiço, B; Rütgen, B; Peleteiro, MC; et al. "Development of a novel antibody-drug conjugated with potent anti-tumor properties against non-Hodgkin´s lymphomas". Trabalho apresentado em Annual Antibody Engineering and Antibody Therapeutics Meeting, San Diego, EUA., 2015.
  19. Silva-Costa, C.; Horácio, A.N.; Aguiar, S.I.; Lopes, JP; Brito, M.J.; Ramirez, M.; Melo-Cristino, J.. "PCV13 serotypes are still major causes of invasive pneumococcal disease in Portugal despite 10 years of conjugate vaccine use in the private market". Trabalho apresentado em 9th World Congress of the World Society for Pediatric Infectious Diseases. Rio de Janeiro, Brazil, 2015.
  20. Dias, J.N.R.; Gil, S.; Aguiar, S.I.; Carrapiço, B; Oliveira, S.; Rütgen, B; Peleteiro, MC; et al. "Development of Highly Specific and Potent Antibody Drug Conjugated Compounds for Treatment of B-Cell Malignancies". Trabalho apresentado em PEGS EUROPE The essential protein engineering summit, Lisbon Portugal, 2015.
  21. Aguiar, S I; Dias, J.N.R.; Neves, V.; Carrapiço, B; Tavares, L.; Castanho, M.A.R.B.; Aires da Silva, F.. "Development of immunoliposomal therapy for treatment of Pneumococcal meningitis". Trabalho apresentado em 3rd iMM postdoc day, 2015.
  22. Diamantino-Miranda, J.; Aguiar, S.I.; Carriço, J.A.; Melo-Cristino, J.; Ramirez, M.. "Conjugate vaccine introduction in Portugal was followed by a decrease of serotypes 6A and 6E but not of serotypes 6B and 6C". Trabalho apresentado em 12th European Meeting on the Molecular Biology of the Pneumococcus (EuroPneumo). Oxford, UK, 2015.
  23. Aguiar, S I; Silva-Costa, C.; Pinho, M.D.; Brito, M J; Ramirez, M.; Melo-Cristino, J.. "Complicated pneumococcal pneumonia in Portugal: Enhanced ethiological diagnosis and serotype distribution". Trabalho apresentado em 33rd Annual Meeting of the European Society for Paediatric Infectious Diseases, Leipzig, Germany, 2015.
  24. Aguiar, S I; Horácio, A.N.; Lopes, JP; Brito, M.J.; Ramirez, M.; Melo-Cristino, J.. "Paediatric invasive pneumococcal disease in Portugal after 10 years of pneumococcal conjugate vaccine use". Trabalho apresentado em 33rd Annual Meeting of the European Society for Paediatric Infectious Diseases, Leipzig, Germany,, 2015.
  25. Dias, J.N.R.; Gil, S.; Aguiar, S I; Oliveira, S; Carrapiço, B; Rütgen, B; Peleteiro, MC; et al. "Development of Highly Specific and Potent Antibody Drug Conjugated Compounds for Treatment of B-Cell Malignancies". Trabalho apresentado em PEGS EUROPE The essential protein engineering summit, 2015.
  26. Diamantino-Miranda, J.; Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Pherotype diversity is not affected by conjugate vaccine induced serotype changes". Trabalho apresentado em 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Barcelona, Spain, 2014.
  27. Aguiar, S I; Brito, M J; Horácio, A.N.; Lopes, JP; Ramirez, M.; Melo-Cristino, J.. "Invasive pneumococcal disease in children and adolescents: incidence of infection and serotype coverage of conjugate vaccines in Portugal". Trabalho apresentado em 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Barcelona, Spain, 2014.
  28. Aguiar, S I; Brito, M.J.; Horácio, A.N.; Lopes, JP; Ramirez, M.; Melo-Cristino, J.. "Declining incidence and changing serotypes in pediatric invasive infections accompany the introduction of expanded valency pneumococcal conjugate vaccines in Portugal". Trabalho apresentado em 9th International Symposium on pneumococci and pneumococcal diseases - ISPPD9, Hyderabad, India, 2014.
  29. Aguiar, S I; Horácio, A.N.; Lopes, JP; Ramirez, M.; Melo-Cristino, J.. "High coverage 13-valent pneumococcal conjugate vaccine in children after ten years of non-universal vaccination with pneumococcal conjugate vaccines in Portugal". Trabalho apresentado em 8th World Congress on Pediatric Infectious Diseases (WSPID), Cape Town, South Africa, 2013.
  30. Aguiar, S I; Horacio, AN; Lopes, J P; Ramirez, M.; Melo-Cristino, J.. "Invasive pneumococcal infections in Portuguese older children and in adolescents: Epidemiological data and new tools for prevention". Trabalho apresentado em 8th World Congress on Pediatric Infectious Diseases (WSPID), Cape Town, South Africa, 2013.
  31. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Expansion and decline of paediatric pneumococcal clones in response to 7-valent conjugate vaccine (PCV7) use in Portugal". Trabalho apresentado em 23rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Berlin, Germany, 2013.
  32. Aguiar, S I; Horácio, A.N.; Diamantino-Miranda, J.; Brito, M J; Ramirez, M.; Melo-Cristino, J.. "Impact of Two years of Non-Universal Pediatric Use of the 13-Valent Conjugate Vaccine (PCV13) in Portugal". Trabalho apresentado em 52nd ICAAC, San Francisco, USA, 2012.
  33. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Use of the 13-Valent Conjugate Vaccine Has the Potential to Eliminate Pilus Carrying Isolates as Causes of Invasive Pneumococcal Disease". Trabalho apresentado em 52nd ICAAC, San Francisco, USA, 2012.
  34. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Recent changes in the proportion of piliated pneumococci: consequences of vaccine use and future prospects". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). London, United Kingdom, 2012.
  35. Horacio, AN; Diamantino-Miranda, J.; Aguiar, S I; Ramirez, M.; Melo-Cristino, J.. "Serotypes causing invasive pneumococcal disease in young adults prior the use of new conjugate vaccines". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). London, United Kingdom, 2012.
  36. Diamantino-Miranda, J.; Horácio, A.N.; Aguiar, S.I.; Ramirez, M.; Melo-Cristino, J.. "Invasive pneumococcal disease in elderly: serotype distribution and antimicrobial resistance before 13-valent conjugate vaccine introduction in Portugal". Trabalho apresentado em 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). London, United Kingdom, 2012.
  37. Horácio, A.N.; Diamantino-Miranda, J.; Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "After 7 Years of PCV7 (7-valent Pneumococcal Conjugate Vaccine) PCV13 Still Covers the Majority of Invasive Pneumococcal Disease (IPD) in Portugal". Trabalho apresentado em 51st ICAAC, Chicago, USA, 2011.
  38. Aguiar, Sandra I; Pinto, F.; Nunes, S.; Sa-Leao, R.; Serrano, I; Melo-Cristino, J; Ramirez, M.. "Serotype 19A lineages in pneumococci recovered from carriage and infection in Portugal". Trabalho apresentado em 7th International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) Tel Aviv, Israel, 2010.
  39. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Characterization of pneumococcal strains of serogroup 6 in Portugal". Trabalho apresentado em 7th International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) Tel Aviv, Israel, 2010.
  40. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Pili distribution among invasive Streptococcus pneumoniae in Portugal after the introduction of the 7-valent conjugate vaccine". Trabalho apresentado em 9th European Meeting on the Molecular Biology of the Pneumococcus (Europneumo), Bern, Switzerland, 2009.
  41. Pinto, FR; Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "S. pneumoniae multistrain genomotyping arrays: optimal choice of control in twocolour experiments". Trabalho apresentado em 6th International Symposium on Pneumococci & Pneumococcal Diseases , Reykjavik, Iceland, 2008.
  42. Aguiar, S I; Serrano, I; Pinto, FR; Melo-Cristino, J.; Ramirez, M.. "Changes in Streptococcus pneumoniae serotypes causing invasive disease with non universal vaccination coverage of the seven-valent conjugate vaccine". Trabalho apresentado em 6th International Symposium on Pneumococci & Pneumococcal Diseases , Reykjavik, Iceland, 2008.
  43. Carriço, J.A.; Pinto, FR; Zemlicková, H.; Jakubu, V.; Nunes, S.; Frazão, N.; Sa-Leao, R.; et al. "Quantitative analysis of congruence of Streptococcus pneumoniae typing methods. Relations between serotype, multi-locus sequence typing and pulse-field gel electrophoresis type assignments". Trabalho apresentado em 6th International Symposium on Pneumococci & Pneumococcal Diseases, Reykjavik, Iceland, 2008.
  44. Aguiar, S I; Serrano, I; PINTO, FR; Melo-Cristino, J.; Ramirez, M.. "Pili distribution among Streptococcus pneumoniae associated with invasive disease". Trabalho apresentado em 18th European Congress of Clinical Microbiology and Infectious Diseases together with the 25th International Congress of Chemotherapy, Barcelona, Spain, 2008.
  45. Aguiar, S I; Melo-Cristino, J.; Ramirez, M.. "Comparison of pneumococci isolate from invasive and non-invasive disease in preschool children". Trabalho apresentado em 18th European Congress of Clinical Microbiology and Infectious Diseases together with the 25th International Congress of Chemotherapy, Barcelona, Spain, 2008.
  46. Aguiar, S I; Frias, M.J.; Santos, L.; Melo-Cristino, J.. "Emergence of optochin resistance among Streptococcus pneumoniae in Portugal". Trabalho apresentado em 8Th European Meeting on the Molecular Biology of the Pneumococcus, Oeiras, Portugal, 2007.
  47. Aguiar, S I; Frias, M.J.; Santos, L.; Melo-Cristino, J.; Ramirez, M.. "Emergence of optochin resistance among Streptococcus pneumoniae in Portugal". Trabalho apresentado em 17th European Congress of Clinical Microbiology and Infectious Diseases together with the 25th International Congress of Chemotherapy, Munich, Germany, 2007.
  48. Serrano, I; Carriço, J.A.; Aguiar, S.I.; Melo-Cristino, J.; Ramirez, M.. "Clonal diversity of invasive Streptococcus pneumoniae from Portuguese children". Trabalho apresentado em 15th European Congress of Clinical Microbiology and Infectious Disease, Copenhagen, Denmark, 2005.
Tese / Dissertação
  1. Aguiar, Sandra I. "Molecular epidemiology of Streptococcus pneumoniae: Impact of PCV7 in the pneumococcal population responsible for invasive pediatric infections". Doutoramento, Universidade de Lisboa Faculdade de Medicina, 2011.
  2. Aguiar, Sandra I. "Caracterização genotípica e fenotípico de Streptococcus pneumoniae responsável por infecção em crianças em idade pré-escolar". Mestrado, Universidade de Lisboa Faculdade de Medicina, 2006.

Propriedade Intelectual

Pedido provisório de patente
  1. 2017. "Single domain antibodies for brain targeting and drug delivery across the blood-brain barrier".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018/11/16 sdAb-immunoliposomes for brain targeting and drug delivery Exploring the boundaries of animal, veterinary and biomedical sciences - CIISA Congress 2018
CIISA/FMV-ULisboa (Lisboa, Portugal)
2017/12 Single domain antibodies for brain targeting and drug delivery Microbiotec
(Porto, Portugal)
2017/02/18 Histone Deacetylase Inhibitors-a novel therapy for canine lymphoma. XIII Congresso Veterinário Montenegro
(Santa Maria da Feira, Portugal)
2017/02/18 Clinical and immunology characterisation of naturally ocorruring canine lymphoma XIII Congresso Hospital Veterinário Montenegro
(Santa Maria da Feira, Portugal)
2013/05/30 The 13-valent pneumococcal conjugate vaccine could prevent a significant proportion of adult invasive pneumococcal disease and covers the majority of resistant isolates XI European Meeting on the Molecular Biology of the Pneumococcus (EuroPneumo)
(Madrid, Espanha)
2013/04/28 Severe pneumococcoal infection in Portugal: serotype distribution and antimicrobial resistance 23rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
(Berlin, Alemanha)
2013/04/12 Pili distribution among Invasive pneumococci in Portugal after 7-valent conjugate vaccine 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
(Viena, Áustria)
2008/11/18 Streptococcus pneumonia em infecções humanas European Antibiotic Day
Infarmed, Direcção Geral da Saúde (Lisboa, Portugal)
2008/04/19 Bacterial multistrain genomotyping arrays: optimal choice of control in twocolour experiments 18th European Congress of Clinical Microbiology and Infectious Diseases
(Barcelona, Espanha)
2007/04/14 Quantitative correspondence between Streptococcus pneumoniae typing methods results: How similar are Serotyping, Multi-Locus Sequence Typing and Pulsed-Field Gel Electrophoresis type assignments? 8Th European Meeting on the Molecular Biology of the Pneumococcus
(Oeiras, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019/01/01 - Atual Dual antibiotic-lipid based nanosystem as a tool to specifically target Staphylococcus aureus biofilms
Orientador
 Ciências Veterinárias (Doutoramento)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2021/03/01 - 2021/06/01 Evaluation of the stability of E. coli DNA and RNA in the presence of organic solvents
Orientador
 Biology (Licenciatura/Bacharelato)
CIISA-FMV Universidade de lisboa, Portugal

Instituto Superior de Psicologia Aplicada Centro de Investigacao, Portugal
2019/10/01 - 2021/06/01 Identificação molecular da mutação MDR1 em raças caninas para sua aplicação prática na Medicina Veterinária Forense. (ENG:Identification of the MDR1 mutation in canine breeds for its application in Forensic Veterinarian Medicine)
Coorientador
 Forensic Sciences (Mestrado)
CIISA-FMV Universidade de lisboa, Portugal

Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
2020/01/02 - 2021/03/01 Efficacy of antibiotic encapsulated liposomes on isolates recovered from urinary tract infections in companion animals
Orientador
 Mestrado em ciências veterinárias (Mestrado)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2019/02/11 - 2020 Validation of liposome efficacy in bacterial infections
Coorientador
 Medicina Veterinária (Mestrado)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2017/07/16 - 2017/07/21 This course, run jointly with Wellcome Genome Campus Advanced Courses and Scientific Conferences, provides hands-on training in the basics of mass spectrometry and proteomics bioinformatics.
Outro
 Proteomics bioinformatics
Joint Wellcome Trust/EBI, Reino Unido
2016/04/04 - 2016/04/15 FMV/ULisboa in collaboration with Utrecht University organize an intensive course in Laboratory Animal Science aimed for researchers who wish to acquire knowledge on the correct use of animals for research purposes.
Outro
 Course on Laboratory Animal Science (Felasa Cat C)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2015/03/05 - 2015/06/14 The program focuses on "deep science" technologies and uses a structured technology marketing process that provides specific support for value creation, supporting projects at different stages of development: (i) assessment of business potential, training and sedimentation of the team, (2) monitoring during the technological and business proof of concept, and (iii) support in attraction and negotiation of financing
Outro
 CoHitec 2015: Training program in technology commercialization
INDEG-IUL, Portugal
2014/10/01 - 2014/11/30 STARTHealth @ ULisboa is a business acceleration program that offers hands-on learning by creating an immersive and near-real environment where participants can feel the common pressures and uncertainties in a startup setup process.
Outro
 Start@Health ULisboa: Entrepreneurship/Business Acceleration Program
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/10/31 - 2013/10/31 Grant writing workshop.
Oficina (workshop)
 Grant writing workshop
Instituto de Medicina Molecular, Portugal
2009/05/31 - 2009/05/31 Nanomedicine nanocourse
Oficina (workshop)
Instituto de Medicina Molecular, Portugal
2008/11/01 - 2009/01/09 Biostatistics course
Outro
 Biostatistics course
Universidade de Lisboa Faculdade de Medicina, Portugal
2008/08/01 - 2008/08/15 Practical Course: Cell Biology of Host- Pathogen interactions
Oficina (workshop)
 Practical Course: Cell Biology of Host- Pathogen interactions
Institut Pasteur, França
2008/01/31 - 2008/01/31 Immunology nanocourse
Oficina (workshop)
 Immunology nanocourse
Instituto de Medicina Molecular, Portugal
2007/11/30 - 2007/11/30 Bioimaging nanocourse
Oficina (workshop)
 Bioimaging nanocourse
Instituto de Medicina Molecular, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/02/05 - 2023/01/31 Pathogens (2076-0817) MDPI

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2020/12/01 - Atual Scientific consulting Extremochem Lda, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020/11/23 - Atual Biopharmaceuticals and Advanced therapies module PhD program in Medicines and Pharmaceutical innovation (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/02/01 - 2021/02/05 Liposome approaches for bacterial infections Medicina Veterinária (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2020/09/23 - 2021/02/01 Immunology Classes Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10/01 - 2018/10/01 BioPharmaceuticals and Advanced Therapies module PhD program in Medicines and Pharmaceutical innovation (Doutoramento) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09/19 - 2017/09/19 Biopharmaceuticals and Advanced Therapies module PhD program in Medicines and Pharmaceutical innovation (Doutoramento) Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/03/01 - 2015/02/28 Microbiologia Clínica Mestrado em Microbiologia (Mestrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2007/03/01 - 2015/02/28 Microbiologia Ciências da Saúde (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2005/03/01 - 2007/02/28 Microbiologia Licenciatura em ciências da nutrição (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal

Membro de associação

Nome da associação Tipo de participação
2020/11/22 - Atual The Antibody Society Membership
2018/01 - Atual The Spanish Portuguese Local Chapter - Control Release Society (SPLC-CRS) Member
2015/06 - Atual European Society for Clinical Microbiology and Infectious Diseases (ECCMID) Member

Tutoria

Tópico Nome do aluno
2019/01/01 - 2019/09/01 Detection of the MDR1 mutation in Portuguese dog breeds Cristina Barroso
2018/09/01 - 2019/09 Development of a new immunoliposome drug delivery system for treatment of pneumococcal meningitis Marta Lisete Santos da Silva
Distinções

Prémio

2014 Second prize for best project
Universidade de Lisboa, Portugal