Ana Cristina Lopes Vasconcelos Ferreira (9D16-BDFB-BD29)

Curriculum Vitae

Ana Cristina Lopes Vasconcelos Ferreira

Ana Ferreira holds a BSc in Genetics and Biotechnology by the University of Trás-Os-Montes e Alto Douro (2010) and a MSc in Pharmaceutical Biotechnology by the Faculty of Pharmacy of the University of Coimbra (2012). As undergraduate student, Ana was recipient of an Integration into Research Grant (BII) from FCT, which allowed her to develop several research competences. She joined the Vectors and Gene Therapy group at the Center for Neuroscience and Cell Biology (CNC) to develop her MSc project, which aimed to develop a pharmacological approach to activate autophagy in Machado-Joseph disease. This work was awarded with the Best Poster presentation by the 1st reSearch Coimbra in Health Sciences in 2013. Ana enrolled the Doctoral Programme in Pharmaceutical Sciences from the Faculty of Pharmacy of the University of Coimbra, supported by a PhD fellowship from FCT. During that period, her research focused on the study of the autophagy pathway dysregulation in Machado Joseph disease as a possible underlying pathological mechanism, aiming at identifying new targets for the treatment of this neurodegenerative disorder. She acquired extensive expertise in cellular and molecular biology, viral vectors, gene and pharmacological therapies and pre-clinical models of the disease. In 2020, she was involved in the implementation of protocols and certification of a laboratory diagnosis of SARS-CoV2 at CNC-Viravector. She also participated as a team member in different projects, that were disseminated in national and international scientific meetings, being the author of a total of 19 oral communications and 15 poster presentations. Ana published 8 papers/book chapters in peer-reviewed international journals (>195 citations; H index of 5), being first author of 2 original papers in top-tier journals (IF=11.45/ 8.09). Over the years she has been invited to give practical classes and lectures in graduate courses and programmes, was responsible for mentoring students in the laboratory, and engaged several scientific communication activities.

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Identificação

Identificação pessoal

Nome completo: Ana Cristina Lopes Vasconcelos Ferreira

Nomes de citação

Ferreira, Ana
Vasconcelos-Ferreira, Ana

Identificadores de autor

Ciência ID: 9D16-BDFB-BD29
ORCID iD: 0000-0002-8968-0641

Endereços de correio eletrónico

ac_ferreira@live.com.pt (Profissional)

Moradas

Center for Neurosciences and Cell Biology. Rua Larga, Faculdade de Medicina da Universidade de Coimbra, Pólo I, 2º Piso - Grupo de Vectores e Terapia Génica , 3004-504, Coimbra, Coimbra, Portugal (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia Molecular
Ciências Naturais - Ciências Biológicas - Biologia Celular
Ciências Médicas e da Saúde - Medicina Básica - Neurociências
Ciências Médicas e da Saúde - Biotecnologia Médica

Formação

	Grau	Classificação
2022/04 Concluído	Doutoramento Ciência Farmacêuticas (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra Faculdade de Farmácia, Portugal
2014 Concluído	Laboratory animal science category B Course, under FELASA guidelines (Curso médio) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012 Concluído	Biotecnologia Farmacêutica (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal "Pharmacological activation of autophagy in Machado-Joseph disease" (TESE/DISSERTAÇÃO)	17
2010 Concluído	Genética e Biotecnologia (Licenciatura) Universidade de Trás-os-Montes e Alto Douro, Portugal "Optimization of pollen DNA isolation from Honey" (TESE/DISSERTAÇÃO)	15
2007 Concluído	Ciências e Tecnologias (Ensino secundário) Escola Secundária Marco de Canaveses, Portugal	17

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2022/07/01 - Atual	Investigador (Investigação)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2019/05/01 - 2022/06/30	Investigador (Investigação)	Universidade de Coimbra, Portugal

2017/02/01 - 2019/02/28	Investigador (Investigação)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2009/09 - 2010/09	Estagiário de Investigação (Investigação)	Universidade de Trás-os-Montes e Alto Douro, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2012/09 - 2022/04	PhD student	CNC.IBILI, Portugal

2020/04 - 2020/07	Research fellow involved in setting up and certification of the laboratory for SARS-CoV-2 molecular testing at CNC-Viravector	Universidade de Coimbra, Portugal
	Universidade de Coimbra- Laboratório de Análises Clínicas, Portugal
2010/09 - 2012/10	Master Student	CNC.IBILI, Portugal

Projetos

Bolsa

	Designação	Financiadores
2019/05 - Atual	BrainHealth 2020: Detecção precoce, neuro-modulação e terapias avançadas para neuropatologias CENTRO-01-0145-FEDER-000008 Bolseiro de Investigação CNC.IBILI, Portugal	Em curso
2017/02/01 - 2019/03	ModelPolyQ - Advanced models of polyglutamine disorders (HD, SCA2, SCA3, SCA7) 02/BIM-JPND_ModelPolyQ/2016 Bolseiro de Investigação

Projeto

	Designação	Financiadores
2020/01 - 2023/12	Centro de Inovação em Biomedicina e Biotecnologia UIDB/04539/2020 Investigador	Em curso
2018/07 - 2022/04	Role of microRNA deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy PTDC/MED-NEU/32309/2017 Investigador	Em curso
2018/07 - 2021/06	Blocking neurodegeneration by spreading of gene silencers PTDC/BTM-SAL/29716/2017 Investigador
2013/03 - 2016/12	Towards the understanding of pathological protein processing and toxicity in Machado-Joseph Disease E-Rare4/0003/2012 Investigador Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Concluído

Produções

Publicações

Artigo em jornal	Ramalho-Santos, João; Varela Amaral, Sara; Correia, Marta Quatorze; Cardoso, João; Pereira de Almeida, Luis ; André Caetano; Ana Catarina Vinhas; et al. "Uma Viagem Rara", Público, 2020, https://www.publico.pt/2020/02/28/ciencia/fotogaleria/viagem-rara-400481.
Artigo em revista	Garcia-Moreno, Hector; Prudencio, Mercedes; Thomas-Black, Gilbert; Solanky, Nita; Jansen-West, Karen R.; Hanna AL-Shaikh, Rana; Heslegrave, Amanda; et al. "Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3". European Journal of Neurology (2022): http://dx.doi.org/10.1111/ene.15373. 10.1111/ene.15373 Vasconcelos-Ferreira, Ana; Martins, Inês Morgado; Lobo, Diana; Pereira, Dina; Lopes, Miguel M.; Faro, Rosário; Lopes, Sara M.; et al. "ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease". Molecular Therapy 30 1 (2022): 370-387. http://dx.doi.org/10.1016/j.ymthe.2021.07.012. 10.1016/j.ymthe.2021.07.012 Vasconcelos-Ferreira, Ana; Carmo-Silva, Sara; Codêsso, José Miguel; Silva, Patrick; Martinez, Alberto Rolim Muro; França Jr, Marcondes Cavalcante; Nóbrega, Clévio; Pereira de Almeida, Luís. "The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado–Joseph disease". Neuropathology and Applied Neurobiology 48 1 (2021): http://dx.doi.org/10.1111/nan.12763. 10.1111/nan.12763 Marcelo, Adriana; Brito, Filipa; Carmo-Silva, Sara; Matos, Carlos A; Alves-Cruzeiro, João; Vasconcelos-Ferreira, Ana; Koppenol, Rebekah; et al. "Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models". Human Molecular Genetics 28 1 (2018): 51-63. http://dx.doi.org/10.1093/hmg/ddy328. 10.1093/hmg/ddy328 Oliveira Miranda, Catarina; Marcelo, Adriana; Silva, Teresa Pereira; Barata, João; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nóbrega, Clévio; et al. "Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease". Molecular Therapy 26 9 (2018): 2131-2151. http://dx.doi.org/10.1016/j.ymthe.2018.07.007. 10.1016/j.ymthe.2018.07.007 Nóbrega, Clévio; Carmo-Silva, Sara; Albuquerque, David; Vasconcelos-Ferreira, Ana; Vijayakumar, Udaya-Geetha; Mendonça, Liliana; Hirai, Hirokazu; Pereira de Almeida, Luís. "Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado–Joseph disease". Brain 138 12 (2015): 3537-3554. http://dx.doi.org/10.1093/brain/awv298. 10.1093/brain/awv298 Nascimento-Ferreira, Isabel; Nóbrega, Clévio; Vasconcelos-Ferreira, Ana; Onofre, Isabel; Albuquerque, David; Aveleira, Célia; Hirai, Hirokazu; Déglon, Nicole; Pereira de Almeida, Luís. "Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease". Brain 136 7 (2013): 2173-2188. http://dx.doi.org/10.1093/brain/awt144. 10.1093/brain/awt144
Capítulo de livro	Nóbrega, Clévio; Simões, Ana Teresa; Duarte-Neves, Joana; Duarte, Sónia; Vasconcelos-Ferreira, Ana; Cunha-Santos, Janete; Pereira, Dina; et al. "Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis". In Advances in Experimental Medicine and Biology, 349-367. Springer International Publishing, 2018. 10.1007/978-3-319-71779-1_18
Poster em conferência	Sara Lopes; Carlos Matos; André Conceição; Frederico Pena; Miguel Lopes; Rui Nobre; Clévio Nóbrega; et al. "CRISPR-CAS9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease". Trabalho apresentado em International Ataxia Research Conference (IARC 2019), Washington, DC. USA, 2019. Sara Lopes; Carlos Matos; André Conceição; Frederico Pena; Miguel Lopes; Rui Nobre; Clévio Nóbrega; et al. "CRISPR-Cas9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease". Trabalho apresentado em International Machado-Joseph Research Disease Conference. Washington, DC. USA, 2019. Vasconcelos-Ferreira, Ana; Inês Martins; Diana Lobo; Dina Pereira; Miguel Lopes; Sara Lopes; Rosário Faro; Clévio Nóbrega; Luís Pereira de Almeida. "Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph Disease". Trabalho apresentado em 2019 International Machado-Joseph Research Disease Conference. Washington, DC. USA, 2019. Vasconcelos-Ferreira, Ana; Inês Morgado Martins; Rosário Faro; Miguel Lopes; Sara Lopes; Dina Pereira; Dineke Verbeek; et al. "Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neuroscience SPN2019, 2019. Dina Pereira; Janete Cunha-Santos; Vasconcelos-Ferreira, Ana; Joana Duarte-Neves; Isabel Onofre; Vítor Carmona; Cláudia Cavadas; Luís Pereira de Almeida. "The role of ageing in polyglutamine-induced neurodegeneration: A study in Machado-Joseph disease models". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neuroscience SPN2019, Lisbon, 2019. Catarina Oliveira Miranda; Adriana Marcelo; Teresa P. Silva; João Barata; Inês Barros; Vasconcelos-Ferreira, Ana; Dina Pereira; et al. "Sustainable phenotypic ameliorations in Machado-Joseph Disease/ Spinocerebellar ataxia type-3 can be reached by repeated systemic administrations of mesenchymal stromal cells- and can be monitored through proton magnetic resonance spectroscopy biomarkers.". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neuroscience SPN2019, Lisbon, 2019. Catarina Oliveira Miranda; Adriana Marcelo; Teresa P. Silva; João Barata; Vasconcelos-Ferreira, Ana; Dina Pereira; Sónia Duarte; et al. "Repeated treatment with mesenchymal stromal cells sustainably alleviates Machado-Joseph Disease and Its Efficacy Can Be Monitored With Neurospectroscopic Biomarkers". Trabalho apresentado em 1st international symposium Secretome With]Out[ Borders, Braga, Portugal, 2018. Catarina Oliveira Miranda; Adriana Marcelo; Teresa P. Silva; João Barata; Vasconcelos-Ferreira, Ana; Dina Pereira; Sónia Duarte; et al. "Repeated mesenchymal stromal cells treatment sustainably alleviates Machado-Joseph Disease/Spinocerebellar ataxia type-3". Trabalho apresentado em 26th Congress of the European Society of Gene and Cell Therapy (ESGCT), Lausanne, Switzerland, 2018. Dina Pereira; Janete Cunha-Santos; Joana Duarte-Neves; Vasconcelos-Ferreira, Ana; Isabel Onofre; Cláudia Cavadas; Luís Pereira de Almeida. "Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models". Trabalho apresentado em 2nd Molecular Biology of Ageing Meeting, Groningen, The Netherlands, 2017. Dina Pereira; Janete Cunha-Santos; Joana Duarte-Neves; Vasconcelos-Ferreira, Ana; Isabel Onofre; Cláudia Cavadas; Luís Pereira de Almeida. "Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models". Trabalho apresentado em 1st Symposium on Aging Research @CNC – Molecular Mechanisms of Aging and Age-Related Diseases, Coimbra, 2016. Clévio Nóbrega; Sara Carmo-Matias; David Albuquerque; Vasconcelos-Ferreira, Ana; Udaya-Geetha Vijayakumar; Liliana Mendonça; Hirokazu Hirai; Luís Pereira de Almeida. "Reestablishing Ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease". Trabalho apresentado em 6th Ataxia Investigators Meeting (AIM), Orlando, USA, 2016. Filipa de Brito; Sara Carmo-Silva; Vasconcelos-Ferreira, Ana; Luís Pereira de Almeida; Clévio Nóbrega. "Pharmacological modulation mutant ataxin-3 and its potential therapeutic effect in Machado Joseph-disease". Trabalho apresentado em XIII CNC Annual Meeting. Coimbra, 2015. Vasconcelos-Ferreira, Ana; Clévio Nóbrega; Dineke Verbeek; Throsten Schmidt; Luís Pereira de Almeida. "Investigating transcriptional modifications of the autophagy pathway in Machado-Joseph disease". Trabalho apresentado em CAG Triplet Repeat Disorders GRS, 2015. Vasconcelos-Ferreira, Ana. "Autophagy activation mitigates motor and neuropathological deficits in mouse models of Machado-Joseph disease". Trabalho apresentado em th Ataxia Investigators Meeting (AIM), Las Vegas, USA, 2014. Vasconcelos-Ferreira, Ana; Clévio Nóbrega; Luís Pereira de Almeida. "Activation of autophagy mitigates neuropathology and motor impairments in mouse models of Machado-Joseph disease". Trabalho apresentado em 1st reSearch Coimbra in Health Sciences, 2013.
Resumo em conferência	Lopes, Sara. "Proceedings of the 24th Annual Meeting of the Portuguese Society of Human Genetics (SPGH – Sociedade Portuguesa de Genética Humana)". 2021. Publicado • 10.1097/md.0000000000023585

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2021/02/18	Importin-8 silencing prevents mutant ataxin-3 aggregation and delays Machado-Joseph Disease progression	51.ª Reunião da Sociedade Portuguesa de Farmacologia 2021 Faculdade de Farmácia da Universidade de Lisboa (Lisboa)
2020/11/20	Permanent inactivation of the ATXN3 gene: a possible therapeutic approach for Machado-Joseph Disease	24ª Reunião da Sociedade Portuguesa Genética Humana Sociedade Portuguesa Genética Humana (Portugal)
2019/11/14	CRISPR-CAS9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease. Flash Talk Presentation.	International Ataxia Research Conference (IARC 2019) (Washington, DC, Estados Unidos)
2019/11	CRISPR-CAS9 systems targeting ATXN3 as therapeutic approaches for Machado-Joseph Disease	2019 MJD International Research Conference (Washington DC, Estados Unidos)
2019/11	Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease	2019 MJD International Research Conference (Washington, DC, Estados Unidos)
2019/11	Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease	International Research Ataxia Conference (IARC) 2019 (Washington, DC, Estados Unidos)
2018/03	Tailoring gene editing strategies for the treatment of Machado-Joseph disease	Portuguese Society of Movement Disorders (SPDMov 2018) (Curia, Portugal)
2018/02	Reinstating levels of dysregulated autophagy-associated transcripts alleviates neuropathology and motor impairments of mouse models of Machado-Joseph disease	XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2018/02	Pharmacological targeting of AMPK pathway as a therapeutic approach to polyglutamine diseases	XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2018/02	Repeated mesenchymal stromal treatment sustainably alleviates Machado-Joseph Disease	XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2018/02	The role of ageing in polyglutamine-induced neurodegeneration: a study in Machado-Joseph Disease models	XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2018/02	Nucleocytoplasmic transport proteins as modulators of Machado-Joseph Disease pathogenesis	XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2017/02	Investigating transcriptional modifications of the autophagy pathway in Machado-Joseph disease	XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2017/02	Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models	XLVII Reunião Anual SPF (Coimbra, Portugal)
2017/01	Is ageing the triggering factor in polyglutamine-induced neurodegeneration? A study in Machado-Joseph disease models	BEB DAY - Not So Usual Insights Into a PhD Center for Neuroscience and Cell Biology (CNC), University of Coimbra (Coimbra, Portugal)
2016/02	CORDYCEPIN: a pharmacological approach to modulate mutant ataxin-3 and it use as a potential therapeutic effect in Machado Joseph-disease	XLVI Reunião da Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2013/05	Beclin-1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease	XIII Reunião da Sociedade Portuguesa de Neurociências (Luso, Portugal)
2013/02	Activation of autophagy mitigates neuropathology and motor impairments in mouse models of Machado-Joseph disease	XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2010/10	Optimization of pollen DNA isolation from Honey	IV Biojornadas (Vila Real, Portugal)

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2015/12/17 - 2015/12/18	Oral and poster presentations evaluation in XIII CNC Annual Meeting (2015/12/17 - 2015/12/18) Encontro (Outra)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/07/03 - 2015/07/04	Scientific retreat of research groups from the Center of Neurosciences and Cell Biology of the University of Coimbra: Neuroendocrinology and Aging (PI Cláudia Cavadas) and Vectors and Gene Therapy (PI Luís Pereira de Almeida) (2015/07/03 - 2015/07/04) Encontro (Coorganizador)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2021/06/04 - 2021/06/04	Invited lecture in society-targeted science outreach activity under the scope of the subject "Cidadania e Desenvolvimento", 12th grade. Conferência	"Conhecer a Doença de Machado-Joseph" Escola Básica e Secundária das Flores, Portugal
2020/04 - 2020/06	Research volunteer- task force for SARS-CoV2 testing Outro	COVID-19 research labs task force Universidade de Coimbra- Laboratório de Análises Clínicas, Portugal
2018/03/20 - 2018/03/20	Brain Awareness Week - Science communication activity Conferência	2018 Brain Awareness Week Escola Secundária da Mealhada, Portugal
2016/11/18 - 2016/11/19	1st International Symposium - Brain Without Borders, held in Coimbra, Portugal. This event offered the opportunity to promote discussion on fundamental and translational research in stem cell biology applied to the Central Nervous System. Congresso	Brain Without Borders Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/09/30 - 2016/09/30	European Researchers' Night 2016. Science communication activities at UC. http://noitedosinvestigadores.pt/ Exposição	European Researchers' Night 2016 Universidade de Coimbra, Portugal
2016/06/27 - 2016/07/01	The CECAD Cologne Summer School provided business and managerial tools that are to be applied in innovative solutions for important real-life aging-challenges, namely awareness about societal challenges, translational research, personalized medicine, patent procedure as well as clinical trials requirements. This course was part of the European Institute of Innovation & Technology (EIT Health) Campus programme. Outro	Entrepreneurial Introductory Translational Research (EITR) Exzellenzcluster CECAD in der Universität zu Köln, Alemanha

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2020/11/23 - 2020/12/04	Biologia Celular: "Deteção de SARS-CoV-2 por RT-PCR"	(Licenciatura)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/17 - 2020/09/18	Métodos e técnicas em Biologia Molecular: "Deteção de SARS-CoV-2 por RT-PCR"	Biologia (Licenciatura)	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/11/26 - 2019/11/26	Regulação Celular: "Autophagia na doença de Machado-Joseph"	Mestrado em Investigação Biomédica (Mestrado)	Universidade de Coimbra Faculdade de Medicina, Portugal
2017/09/26 - 2017/10/06	Stereotaxic surgery: "Advanced anesthesia for surgical or prolonged procedures in mice and rats (skills)"	Course of Sciences in Laboratory animals (Outros)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/09/26 - 2017/10/06	Stereotaxic surgery: "Principles of surgery (skills)"	Course of Sciences in Laboratory Animals	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/06/16 - 2016/06/16	Advanced Therapies: "Pharmacological activation of autophagy in neurodegenerative disorders"	Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento)	Universidade de Coimbra, Portugal

Entrevista (jornal / revista)

	Descrição da atividade	Jornal / Forum
2022/01	Interview within the scope of the published study "The autophagy-enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado Joseph disease".	Jornal "A Verdade"

Membro de associação

	Nome da associação	Tipo de participação
2022 - Atual	Zero- Associação Sistema Terrestre Sustentável
2019 - Atual	Sociedade Portuguesa de Neurociências

Tutoria

	Tópico	Nome do aluno
2013 - Atual	Lab rotation students	Over 10
2020/08/01 - 2020/11/30	Estabelicimento das condições para produção e purificação da proteína ataxina-3	Tomás Sousa
2020/08/01 - 2020/10/31	Expressão e purificação da proteína ataxina-3	Adriana Mata

Distinções

Prémio

2013	Best Poster presentation- reSearch Coimbra in Health Sciences

Outra distinção

2019	Travel bursary to attend the MJD Satellite Conference in Washington DC, USA. MJD Foundation, Austrália
2019	Young investigator bursary to attend the International Ataxia Research Conference 2019 in Washington DC, USA.
2016	Travel bursary to attend the CECAD Short Course on Entrepreneurial Introductory Translational Research (EITR)
2008	Scholarship for the Integration in Scientific Research (BII) Fundação para a Ciência e a Tecnologia, Portugal