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Fabíola Costa is specialized in the development of antimicrobial coatings through antibiotic-free strategies, namely by applying polymers with intrinsic antimicrobial properties or by chemically modifying polymers with Antimicrobial Peptides. She is currently Junior researcher at i3S at the Bioengineered surfaces team. She is also Invited Assistant professor at Instituto de Ciências Biomédicas Abel Salazar (ICBAS) of the University of Porto. With a background of Pharmaceutical sciences (Bsc) and a Master in Applied Microbiology, she decided to focus on the development of antimicrobial coatings during her PhD in Biomedical Engineering at Faculty of Engineering of the University of Porto (FEUP), where she graduated Cum Laude in 2015. Since then, F.Costa has collaborated in 9 projects and is currently the Principal Investigator of AntiBioCoat project financed by CaixaImpulse program 2018 (La Caixa Foundation). F.Costa has been engaged in several technology transfer programs including RESOLVE 2016: Technology Transfer Ignition Program in the Health Sector, Portugal (Norte2020) and HiTech- training Program in translating technology and entrepreneurship skills from Porto Business School (2018). F.Costa has been awarded 7 times, including Everis awards 2019 semi-finalist at National level Lisbon andBest Innovation Project Award, RESOLVE 1st Edition, with AntiBioCoat Project (2018). F.Costa has published 1 patent, 10 peer-reviewed papers in Q1 international journals, which resulted on more than 450 citations, and 3 book chapters.
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Identificação

Identificação pessoal

Nome completo
Fabíola Maria Tavares Alves da Costa Moutinho

Nomes de citação

  • Costa, Fabíola

Identificadores de autor

Ciência ID
AC1C-68E7-6E81
ORCID iD
0000-0001-8981-7049
Formação
Grau Classificação
2015
Concluído
 Doctoral Program in Biomedical Engineering (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
"Surface-immobilized Antimicrobial Peptides (AMPs) for prevention of implant-related Osteomyelitis" (TESE/DISSERTAÇÃO)
 Cum Laude
2007
Concluído
 Food science and technology (Mestrado)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
"Genotypic analysis of Candida albicans isolates obtained from removable prosthesis wearers" (TESE/DISSERTAÇÃO)
 Approved with distinction
2004
Concluído
 Pharmaceutical Sciences (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"Pharmaceutical Sciences" (TESE/DISSERTAÇÃO)
 14
Produções

Publicações

Artigo em conferência
  1. Costa, F.; Maia, S.; Gomes, P.; Martins, M.C.L.. "Covalent immobilization of human lactoferrin-derived peptide (hLF1-11) for the development of an antimicrobial surface". 2011.
Artigo em revista
  1. Monteiro, C.; Costa, F.; Pirttilä, A. M.; Tejesvi, M. V.; Martins, M.C.L.. "Prevention of urinary catheter-associated infections by coating antimicrobial peptides from crowberry endophytes". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-47108-5.
    10.1038/s41598-019-47108-5
  2. Costa, B.; Mota, R.; Parreira, P.; Tamagnini, P.; Martins, M.C.L.; Costa, F.. "Broad-spectrum anti-adhesive coating based on an extracellular polymer from a marine cyanobacterium". Marine Drugs 17 4 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065414702&partnerID=MN8TOARS.
    10.3390/md17040243
  3. Barbosa, M.; Costa, F.; Monteiro, C.; Duarte, F.; Martins, M.C.L.; Gomes, P.. "Antimicrobial coatings prepared from Dhvar-5-click-grafted chitosan powders". Acta Biomaterialia (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058393291&partnerID=MN8TOARS.
    10.1016/j.actbio.2018.12.001
  4. Querido, M.M.; Felgueiras, H.P.; Rai, A.; Costa, F.; Monteiro, C.; Borges, I.; Oliveira, D.; Ferreira, L.; Martins, M.C.L.. "Cecropin–Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation". Advanced Materials Interfaces 5 24 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85055708783&partnerID=MN8TOARS.
    10.1002/admi.201801390
  5. Barbosa, M.; Vale, N.; Costa, F.M.T.A.; Martins, M.C.L.; Gomes, P.. "Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne “click” reaction conditions". Carbohydrate Polymers 165 (2017): 384-393. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013929503&partnerID=MN8TOARS.
    10.1016/j.carbpol.2017.02.050
  6. Costa, F.; Sousa, D.M.; Parreira, P.; Lamghari, M.; Gomes, P.; Martins, M.C.L.. "N-acetylcysteine-functionalized coating avoids bacterial adhesion and biofilm formation". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85037721926&partnerID=MN8TOARS.
    10.1038/s41598-017-17310-4
  7. Monteiro, C.; Fernandes, M.; Pinheiro, M.; Maia, S.; Seabra, C.L.; Ferreira-Da-Silva, F.; Costa, F.; et al. "Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78". Biochimica et Biophysica Acta - Biomembranes 1848 5 (2015): 1139-1146. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923289681&partnerID=MN8TOARS.
    10.1016/j.bbamem.2015.02.001
  8. Costa, F.M.T.A.; Maia, S.R.; Gomes, P.A.C.; Martins, M.C.L.. "Dhvar5 antimicrobial peptide (AMP) chemoselective covalent immobilization results on higher antiadherence effect than simple physical adsorption". Biomaterials 52 1 (2015): 531-538. http://www.scopus.com/inward/record.url?eid=2-s2.0-84932632783&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2015.02.049
  9. Costa, F.; Maia, S.; Gomes, J.; Gomes, P.; Martins, M.C.L.. "Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity". Acta Biomaterialia 10 8 (2014): 3513-3521. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903724424&partnerID=MN8TOARS.
    10.1016/j.actbio.2014.02.028
  10. Costa, F.; Carvalho, I.F.; Montelaro, R.C.; Gomes, P.; Martins, M.C.L.. "Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces". Acta Biomaterialia 7 4 (2011): 1431-1440. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952187401&partnerID=MN8TOARS.
    10.1016/j.actbio.2010.11.005
  11. Costa, F.; Manaia, C.M.; Figueiral, M.H.; Pinto, E.. "Genotypic analysis of Candida albicans isolates obtained from removable prosthesis wearers". Letters in Applied Microbiology 46 4 (2008): 445-449. http://www.scopus.com/inward/record.url?eid=2-s2.0-41049101995&partnerID=MN8TOARS.
    10.1111/j.1472-765X.2008.02336.x
Capítulo de livro
  1. Costa, F.; Teixeira, C.; Gomes, P.; Martins, M.C.L.. "Clinical application of AMPs". 281-298. 2019.
    10.1007/978-981-13-3588-4_15
  2. Martins, MCL. "Chapter 13. Antimicrobial Peptides (AMP) biomaterial coatings for tissue repair". 2017.
  3. Silva, R.; Boccaccini, A.R.. "Chapter 7. Fibrous protein-based biomaterials (silk, keratin, elastin and resilin proteins) for tissue regeneration and repair". Reino Unido, 2017.
Tese / Dissertação
  1. Costa, Fabíola. "Surface-immobilized Antimicrobial Peptides (AMPs) for prevention of implant-related Osteomyelitis". Doutoramento, Universidade do Porto Faculdade de Engenharia, 2015.
  2. Costa, Fabíola. "Genotypic analysis of Candida albicans isolates obtained from removable prosthesis wearers". Mestrado, Universidade Católica Portuguesa Escola Superior de Biotecnologia, 2007.

Propriedade Intelectual

Pedido provisório de patente
  1. 2018. "Uses of cyanobacterium extracellular polymer, compositions, coated surfaces or articles".