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Joao Matos. É Professor Catedrático e Investigador principal nos laboratórios Max Perutz , Universidade de Vienna. Publicou 40 artigos em revistas especializadas. Atua na(s) área(s) de Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Bioquímica. Nas suas atividades profissionais interagiu com mais de 86 colaborador(es) em coautorias de trabalhos científicos.
Identificação

Identificação pessoal

Nome completo
Joao Matos

Nomes de citação

  • Matos, Joao

Identificadores de autor

Ciência ID
BE16-2BB4-50D8
ORCID iD
0000-0002-3754-3709
Google Scholar ID
citations?user=-Ga7GGIAAAAJ&hl

Telefones

Telefone
  • (+43) 1427774419 (Profissional)

Moradas

  • Max Perutz Labs, Dr. Bohr-Gasse 9, 1030, Vienna, Vienna, Áustria (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Alemão Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2)
Formação
Grau Classificação
2013/12/28
Concluído
 Biochemistry of DNA repair (Pós-doutoramento)
Cancer Research UK, Reino Unido
2008/12/31
Concluído
 Cell cycle control of chromosome segregation (Pós-doutoramento)
Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha
2007/11/19
Concluído
 Biology (Doutoramento)
Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha
"Control of Chromosome segregation in meiosis" (TESE/DISSERTAÇÃO)
 Summa cum laude
1997 - 2002/06/15
Frequentou
 Biochemistry (Licenciatura)
Especialização em Biochemistry
Universidade do Algarve, Portugal
1994/09/01 - 1997/06/30
Frequentou
 Ciencias e Tecnologias (Ensino secundário)
Escola Secundaria Martins Sarmento, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/09/01 - Atual Investigador principal (carreira) (Investigação) Max F Perutz Laboratories Center of Molecular Biology, Áustria
2014/01/01 - Atual Investigador principal (carreira) (Investigação) Eidgenössische Technische Hochschule Zürich, Suiça
2009/03/01 - 2013/12/31 Pós-doutorado (Investigação) Cancer Research UK, Reino Unido
2008/01/01 - 2009/01/01 Pós-doutorado (Investigação) Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/01/07 - Atual Professor Auxiliar (Docente Universitário) Eidgenössische Technische Hochschule Zürich, Suiça

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2003/07/01 - 2007/12/31 PhD student Max-Planck-Institut für molekulare Zellbiologie und Genetik, Alemanha
Projetos

Bolsa

Designação Financiadores
2015/12/01 - Atual Upgrade of a Titan Krios electron cryo-microscope for single particle analysis and tomography
164092
Investigador responsável
Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2009/03 - Atual Coordination of DNA repair and segregation during meiosis and mitosis
153058
Investigador responsável
Eidgenössische Technische Hochschule Zürich, Suiça
 Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
Concluído
2018/09/01 - 2022/08/31 Control of DNA breakage by structure-selective endonucleases during meiosis and mitosis
176108
Investigador responsável
Eidgenössische Technische Hochschule Zürich, Suiça
 Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2018/01/01 - 2020/12/31 Regulation of anti-crossover helicases during meiosis
ETH-31 17-2
Investigador responsável
Eidgenössische Technische Hochschule Zürich, Suiça
2015/04/01 - 2020/03/31 Rewiring DNA repair for genome stability and haploidisation
155823
Investigador responsável
Eidgenössische Technische Hochschule Zürich, Suiça
Em curso
2016/09/01 - 2019/08/31 Regulation of meiotic crossing over by Polo kinase Cdc5
ETH-47 16-1 P
Investigador responsável
Eidgenössische Technische Hochschule Zürich, Suiça
Em curso
2010/04/01 - 2013/03/31 Regulation of GEN1-mediated Holliday junction resolution in homologous recombination and DNA repair
LT000343/2010-L
Bolseiro de Pós-Doutoramento
HFSP - Human Frontiers Science Program, França
2010/04/01 - 2013/03/31 Regulation of GEN1-mediated Holliday junction resolution in homologous recombination and DNA repair
HFSP 000343/2010-L
Bolseiro de Pós-Doutoramento
Concluído
Produções

Publicações

Artigo em revista
  1. King, G.A.; Wettstein, R.; Varberg, J.M.; Chetlapalli, K.; Walsh, M.E.; Gillet, L.C.J.; Hernández-Armenta, C.; et al. "Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization". Journal of Cell Biology 222 2 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85148653863&partnerID=MN8TOARS.
    10.1083/jcb.202204039
  2. Altmannova, V.; Spirek, M.; Orlic, L.; Jekabsons, A.; Clarence, T.; Henggeler, A.; Mlcouskova, J.; et al. "The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination". iScience 25 11 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85141242414&partnerID=MN8TOARS.
    10.1016/j.isci.2022.105439
  3. Pogliano, C.B.; Ceppi, I.; Giovannini, S.; Petroulaki, V.; Palmer, N.; Uliana, F.; Gatti, M.; et al. "The CDK1-TOPBP1-PLK1 axis regulates the Bloom's syndrome helicase BLM to suppress crossover recombination in somatic cells". Science Advances 8 5 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85124152880&partnerID=MN8TOARS.
    10.1126/sciadv.abk0221
  4. Alonso-Ramos, P.; Álvarez-Melo, D.; Strouhalova, K.; Pascual-Silva, C.; Garside, G.B.; Arter, M.; Bermejo, T.; et al. "The cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis". International Journal of Molecular Sciences 22 18 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85114647365&partnerID=MN8TOARS.
    10.3390/ijms22189811
  5. Cannavo, E.; Sanchez, A.; Anand, R.; Ranjha, L.; Hugener, J.; Adam, C.; Acharya, A.; et al. "Publisher Correction: Regulation of the MLH1–MLH3 endonuclease in meiosis (Nature, (2020), 586, 7830, (618-622), 10.1038/s41586-020-2592-2)". Nature 590 7844 (2021): E29-E29. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100114141&partnerID=MN8TOARS.
    10.1038/s41586-020-03111-9
  6. "Regulation of the MLH1-MLH3 endonuclease in meiosis.". Nature (2020): https://doi.org/10.1038/s41586-020-2592-2.
    10.1038/s41586-020-2592-2
  7. "Phosphorylation of the RecQ Helicase Sgs1/BLM Controls Its DNA Unwinding Activity during Meiosis and Mitosis.". Developmental cell (2020): https://doi.org/10.1016/j.devcel.2020.05.016.
    10.1016/j.devcel.2020.05.016
  8. Julia Bittmann; Rokas Grigaitis; Lorenzo Galanti; Silas Amarell; Florian Wilfling; Joao Matos; Boris Pfander. "An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases". eLife 9 (2020): https://doi.org/10.7554/eLife.52459.
    10.7554/eLife.52459
  9. Tobias Zachs; Andreas Schertel; João Medeiros; Gregor L Weiss; Jannik Hugener; Joao Matos; Martin Pilhofer. "Fully automated, sequential focused ion beam milling for cryo-electron tomography". eLife 9 (2020): https://doi.org/10.7554/eLife.52286.
    10.7554/eLife.52286
  10. Szmyd, R.; Niska-Blakie, J.; Diril, M.K.; Nunes, P.R.; Tzelepis, K.; Lacroix, A.; van Hul, N.; et al. "Correction: Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality (Oncogene, (2019), 38, 7, (998-1018), 10.1038/s41388-018-0464-0)". Oncogene 39 9 (2020): 2030-2030. http://www.scopus.com/inward/record.url?eid=2-s2.0-85080036670&partnerID=MN8TOARS.
    10.1038/s41388-019-1114-x
  11. "Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops.". Molecular cell (2019): https://doi.org/10.1016/j.molcel.2019.10.026.
    10.1016/j.molcel.2019.10.026
  12. "Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.". Molecular cell (2019): http://europepmc.org/articles/PMC6715774.
    10.1016/j.molcel.2019.06.022
  13. Arter, M.; Hurtado-Nieves, V.; Oke, A.; Zhuge, T.; Wettstein, R.; Fung, J.C.; Blanco, M.G.; Matos, J.. "Regulated Crossing-Over Requires Inactivation of Yen1/GEN1 Resolvase during Meiotic Prophase I". Developmental Cell 45 6 (2018): 785-800.e6. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048163037&partnerID=MN8TOARS.
    10.1016/j.devcel.2018.05.020
  14. Szmyd, R.; Niska-Blakie, J.; Diril, M.K.; Renck Nunes, P.; Tzelepis, K.; Lacroix, A.; van Hul, N.; et al. "Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality". Oncogene (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053065579&partnerID=MN8TOARS.
    10.1038/s41388-018-0464-0
  15. Villiger, L.; Grisch-Chan, H.M.; Lindsay, H.; Ringnalda, F.; Pogliano, C.B.; Allegri, G.; Fingerhut, R.; et al. "Treatment of a metabolic liver disease by in vivo genome base editing in adult mice". Nature Medicine 24 10 (2018): 1519-1525. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054571026&partnerID=MN8TOARS.
    10.1038/s41591-018-0209-1
  16. Agnès H Michel; Riko Hatakeyama; Philipp Kimmig; Meret Arter; Matthias Peter; Joao Matos; Claudio De Virgilio; Benoît Kornmann. "Functional mapping of yeast genomes by saturated transposition". eLife 6 (2017): https://doi.org/10.7554/eLife.23570.
    10.7554/eLife.23570
  17. Michel AH; Hatakeyama R; Kimmig P; Arter M; Peter M; Matos J; De Virgilio C; Kornmann B. "Functional mapping of yeast genomes by saturated transposition.". (2017): http://europepmc.org/abstract/med/28481201.
    10.7554/elife.23570
  18. Princz LN; Wild P; Bittmann J; Aguado FJ; Blanco MG; Matos J; Pfander B. "Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis.". (2017): http://europepmc.org/abstract/med/28096179.
    10.15252/embj.201694831
  19. Pfander, B.; Matos, J.. "Control of Mus81 nuclease during the cell cycle". FEBS Letters 591 14 (2017): 2048-2056. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022337369&partnerID=MN8TOARS.
    10.1002/1873-3468.12727
  20. Duda, H.; Arter, M.; Gloggnitzer, J.; Teloni, F.; Wild, P.; Blanco, M.G.; Altmeyer, M.; Matos, J.. "Erratum: A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis (Developmental Cell (2016) 39(6) (740–755)(S1534580716308292)(10.1016/j.devcel.2016.11.017))". Developmental Cell 40 4 (2017): 421-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014074817&partnerID=MN8TOARS.
    10.1016/j.devcel.2017.02.015
  21. Duda H; Arter M; Gloggnitzer J; Teloni F; Wild P; Blanco MG; Altmeyer M; Matos J. "A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis.". (2016): http://europepmc.org/abstract/med/27997828.
    10.1016/j.devcel.2016.11.017
  22. Bonner JN; Choi K; Xue X; Torres NP; Szakal B; Wei L; Wan B; et al. "Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates.". (2016): http://europepmc.org/abstract/med/27373152.
    10.1016/j.celrep.2016.06.015
  23. Wild P; Matos J. "Cell cycle control of DNA joint molecule resolution.". (2016): http://europepmc.org/abstract/med/26970388.
    10.1016/j.ceb.2016.02.018
  24. Blanco, Miguel G.; Matos, Joao. "Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1". Frontiers in Genetics 6 (2015): 253-253. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI201500646403&KeyUID=BCI:BCI201500646403.
    10.3389/fgene.2015.00253
  25. West SC; Blanco MG; Chan YW; Matos J; Sarbajna S; Wyatt HD. "Resolution of Recombination Intermediates: Mechanisms and Regulation.". (2015): http://europepmc.org/abstract/med/26370409.
    10.1101/sqb.2015.80.027649
  26. Gritenaite, Dalia; Princz, Lissa N.; Szakal, Barnabas; Bantele, Susanne C. S.; Wendeler, Lina; Schilbach, Sandra; Habermann, Bianca H.; et al. "A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication". Genes & Development 28 14 (2014): 1604-1619.
    10.1101/gad.240515.114
  27. Blanco, Miguel G.; Matos, Joao; West, Stephen C.. "Dual Control of Yen1 Nuclease Activity and Cellular Localization by Cdk and Cdc14 Prevents Genome Instability". Molecular Cell 54 1 (2014): 94-106.
    10.1016/j.molcel.2014.02.011
  28. Matos, Joao; West, Stephen C.. "Holliday junction resolution: Regulation in space and time". DNA Repair 19 (2014): 176-181.
    10.1016/j.dnarep.2014.03.013
  29. Wyatt HD; Sarbajna S; Matos J; West SC. "Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells.". (2013): http://europepmc.org/abstract/med/24076221.
    10.1016/j.molcel.2013.08.035
  30. Matos, Joao; Blanco, Miguel G.; West, Stephen C.. "Cell-Cycle Kinases Coordinate the Resolution of Recombination Intermediates with Chromosome Segregation". Cell Reports 4 1 (2013): 76-86.
    10.1016/j.celrep.2013.05.039
  31. Matos, Joao; Blanco, Miguel G.; Maslen, Sarah; Skehel, J. Mark; West, Stephen C.. "Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and Mitosis". Cell 147 1 (2011): 158-172.
    10.1016/j.cell.2011.08.032
  32. Blanco, Miguel G.; Matos, Joao; Rass, Ulrich; Ip, Stephen C. Y.; West, Stephen C.. "Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae". DNA Repair 9 4 (2010): 394-402.
    10.1016/j.dnarep.2009.12.017
  33. Rass, Ulrich; Compton, Sarah A.; Matos, Joao; Singleton, Martin R.; Ip, Stephen C. Y.; Blanco, Miguel G.; Griffith, Jack D.; West, Stephen C.. "Mechanism of Holliday junction resolution by the human GEN1 protein". Genes & Development 24 14 (2010): 1559-1569.
    10.1101/gad.585310
  34. Matos, Joao; Lipp, Jesse J.; Bogdanova, Aliona; Guillot, Sylvine; Okaz, Elwy; Junqueira, Magno; Shevchenko, Andrej; Zachariae, Wolfgang. "Dbf4-Dependent Cdc7 Kinase Links DNA Replication to the Segregation of Homologous Chromosomes in Meiosis I". Cell 135 4 (2008): 662-678.
    10.1016/j.cell.2008.10.026
  35. Petronczki, Mark; Matos, Joao; Mori, Saori; Gregan, Juraj; Bogdanova, Aliona; Schwickart, Martin; Mechtler, Karl; et al. "Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1". Cell 126 6 (2006): 1049-1064.
    10.1016/j.cell.2006.07.029
  36. Oelschlaegel, T; Schwickart, M; Matos, J; Bogdanova, A; Camasses, A; Havlis, J; Shevchenko, A; Zachariae, W. "The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1". Cell 120 6 (2005): 773-788.
    10.1016/j.cell.2005.01.032
  37. Katis, VL; Matos, J; Mori, S; Shirahige, K; Zachariae, W; Nasmyth, K. "Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion during yeast meiosis". Current Biology 14 24 (2004): 2183-2196.
    10.1016/j.cub.2004.12.020
Livro
  1. Grigaitis, R.; Susperregui, A.; Wild, P.; Matos, J.. Characterization of DNA helicases and nucleases from meiotic extracts of S. cerevisiae. 2018.
    10.1016/bs.mcb.2018.03.029
  2. Matos, J.; West, S.C.. Analysis of Structure-Selective Endonuclease Activities From Yeast and Human Extracts. 2017.
    10.1016/bs.mie.2017.03.005
Pré-impressão
  1. Jannik Hugener; Jingwei Xu; Rahel Wettstein; Lydia Ioannidi; Daniel Velikov; Florian Wollweber; Adrian Henggeler; Joao Matos; Martin Pilhofer. "FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis". 2024. https://doi.org/10.1101/2024.03.26.586525.
    10.1101/2024.03.26.586525
Tese / Dissertação
  1. Matos, Joao. "Control of chromosome segregation in meiosis". Doutoramento, Technische Universität Dresden, 2007.

Outros

Outra produção
  1. Meiotic Nuclear Pore Complex Remodeling Provides Key Insights into Nuclear Basket Organization. 2022. King, G.A.; Wettstein, R.; Varberg, J.M.; Chetlapalli, K.; Walsh, M.E.; Gillet, L.; Hernández-Armenta, C.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85130810763&partnerID=MN8TOARS.
    10.1101/2022.04.14.488376
  2. Regulatory Control of RecQ Helicase Sgs1/BLM during Meiosis and Mitosis. 2020. Grigaitis, R.; Ranjha, L.; Wild, P.; Kasaciunaite, K.; Ceppi, I.; Kissling, V.; Susperregui, A.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85109662689&partnerID=MN8TOARS.
    10.2139/ssrn.3508884
  3. Regulation of the MLH1-MLH3 endonuclease in meiosis. 2020. Cannavo, E.; Sanchez, A.; Anand, R.; Ranjha, L.; Hugener, J.; Adam, C.; Acharya, A.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85102721781&partnerID=MN8TOARS.
    10.1101/2020.02.12.946293
  4. The Cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis. 2019. Alonso-Ramos, P.; Álvarez-Melo, D.; Strouhalova, K.; Pascual-Silva, C.; Garside, G.B.; Arter, M.; Bermejo, T.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115744324&partnerID=MN8TOARS.
    10.1101/571083
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/07/16 Network rewiring of DNA repair during mitotic proliferation and meiosis FASEB conference
(Denver, Estados Unidos)
2019/03/14 Rewiring DNA repair for genome stability or genome haploidisation EMBO YIP meeting
(Singapore, Singapura)
2018/09/18 Network rewiring of homologous recombination during mitotic proliferation and meiosis EMBO Workshop - DNA replication, chromosome segregation and fate decisions
(Kylliini, Grécia)
2018/09/13 Rewiring DNA repair for genome stability or genome haploidisation International meeting «Levures, Modèles et Outils»
(Rheinau, Suiça)
2018/05/23 Regulation of structure-selective endonucleases during meiosis: implications for crossover maturation and patterning Mechanisms of Recombination
(London, Reino Unido)
2018/05/18 Rewiring DNA repair for genome stability or genome haploidisation EMBO YIP Meeting
(Vienna, Áustria)
2018/05/15 Rewiring DNA repair for genome stability or genome haploidisation Annual Technical Meeting
Petroleum Society of Canada (Amsterdam, Países Baixos)
2017/11/11 DNA repair nucleases: putting chromosomes through the shredder EMBO Conference: The DNA damage response in cell physiology and disease
(Cape Sounio, Grécia)
2017/08/31 Regulation of structure-selective endonucleases during meiosis: implications for crossover maturation and distribution EMBO Meiosis meeting
(Hvar, Croácia)
2017/06/26 A mechanism for controlled breakage of under-replicated chromosomes during mitosis 25th Wilhelm Bernhard Workshop on the Cell Nucleus
(Nizhny Novgorod, Rússia)
2016/09/19 A mechanism for controlled breakage of under-replicated chromosomes during mitosis EMBO Workshop Nuclear Function and Cell Fate Choice
(Kyllini, Grécia)
2016/09/14 A mechanism for controlled breakage of under-replicated chromosomes during mitosis Offshore Technology Conference Asia
German Society for Research on DNA Repair (Essen, Alemanha)
2016/06/08 A mechanism for controlled breakage of under-replicated chromosomes during mitosis Swiss meeting on Genome Stability and Chromatin Dynamics
(Emmetten, Suiça)
2016/05/18 A mechanism for controlled breakage of under-replicated chromosomes during mitosis Mechanisms of Recombination
Abcam conference (Alicante, Espanha)
2015/11/04 A mechanism for controlled breakage of under-replicated chromosomes during mitosis Workshop on structure-selective endonucleases
(Brno, República Checa)
2012/07/04 Controlling nucleases that determine our genetic make-up HFSP awardees meeting
(Daegu, Coreia do Sul)
2012/06/02 Controlling nucleases that determine our genetic make-up Gordon Research Seminar
(New London, Estados Unidos)
2012/04/24 Cdc5/PLK1 and Cdc28/CDK activate nucleases to coordinate the completion of DNA repair with chromosome segregation Cell Cycle Club - Abcam
(London, Reino Unido)
2011/09/05 Regulatory control of meiotic joint molecule resolution EMBO Meiosis meeting
(Paestum, Itália)
2011/01/14 Timing and control of Holliday junction resolution in budding yeast meiosis Genome stability Network
(Cambridge, Reino Unido)
2009/09/25 Regulation of kinetochore orientation during meiosis EMBO workshop on Polo-like kinases
IEEE (Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2018/08/01 - Atual Monitoring meiotic recombination in situ using electron cryotomography
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2018/08/01 - Atual Regulation of Holliday junction resolution during meiosis
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2016/03/01 - Atual Regulation of anti-crossover helicases during meiosis
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2015/09/01 - Atual Regulation of meiotic crossing over by Polo kinase Cdc5
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2014/06/01 - 2019/01/09 Temporal and spatial regulation of crossing-over in meiosis
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2015/01/31 - 2018/12 Identification and characterization of novel regulators of recombinational DNA repair during mitotic proliferation and meiosis
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça
2014/01/01 - 2017/05/31 Cell cycle regulation of DNA breakage by MUS81 nuclease
Orientador
Eidgenössische Technische Hochschule Zürich, Suiça

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/09/30 - Atual EMBO YIP Sectorial meeting - Genome Stability (2019/09/30 - 2019/10/02)
Encontro (Coorganizador)
2016/01/01 - Atual Special seminar series - Institute of Biochemistry - ETH Zurich (2016/01/01)
Seminário (Coorganizador)
 Eidgenössische Technische Hochschule Zürich, Suiça

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019/01/10 Temporal and spatial regulation of crossing-over in meiosis
Orientador
 Meret Arter (Doutoramento)
2018/12/05 Identification and characterization of novel regulators of recombinational DNA repair during mitotic proliferation and meiosis
Orientador
 Aitor Susperregui (Doutoramento)
2018/11/22 Defining Cancer-Specific Alterations in Genome Integrity Maintenance
Arguente
 Federico Teloni (Doutoramento)
2018/08/27 A novel pathway for resolution of collisions between DNA replication and transcription machineries
Arguente
 Naga Raja Chappidi (Doutoramento)
2018/06/28 FANCM translocase promotes telomere stability and cell viability in ALT (Alternative Lengthening of Telomeres) cells
Arguente
 Richard Pentz (Doutoramento)
2018/05/08 Unraveling the role of FANCA in the Fanconi Anemia pathway
Arguente principal
 Leon Burgdorf (Mestrado)
2018/04/03 Investigation of the E.coli recombinase RecA by Time-Resolved Analysis by cryo-EM (TraceM) Märt-Erik Mäeots (Mestrado)
2018/03/16 Mechanistic insights into final maturation of the eukaryotic large ribosomal subunit
Arguente
 Purnima Klingauf (Doutoramento)
2018/03/16 Telomeric states in cancer development
Arguente
 Jana Majerská (Doutoramento)
2017/09/14 Initial functional and structural characterisation of human GID complex
Arguente
 Diana Stafa (Doutoramento)
2017/09/13 Telomere Instability in Human Cells - Replication stress-induced mitotic DNA synthesis at difficult-to-replicate loci
Arguente
 Özgün Özer (Doutoramento)
2017/05/18 Cell cycle regulation of DNA breakage by MUS81 nuclease
Orientador
 Heika Duda (Doutoramento)
2017/05/17 Elucidating the role of the ANN complex in human ribosome biogenesis
Arguente
 Eva Vogt (Mestrado)

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2016/01/01 - Atual Steering committee of the PhD program - Zurich Molecular Life Sciences
Membro
 Eidgenössische Technische Hochschule Zürich, Suiça
2015/01/01 - Atual Travel grants committee - MLS PhD program
Membro
 Eidgenössische Technische Hochschule Zürich, Suiça

Universität Zürich, Suiça
2014/01/01 - Atual Board Member of The Institute of Biochemistry
Membro
 Eidgenössische Technische Hochschule Zürich, Suiça
Distinções

Prémio

2021 ERC Consolidator Grant
European Research Council, Bélgica
2017 EMBO Young Investigator
European Molecular Biology Laboratory, Alemanha
2015 Starting Grant - (ERC-replacement, Switzerland)
2009 Otto-Hahn Medal
Max-Planck-Gesellschaft zur Förderung der Wissenschaften, Alemanha

Outra distinção

2010 HFSP Long-Term fellowship
2009 EMBO Long-Term Fellowship