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Hugo Fernandes (HF) obtained his Applied Biology degree from the University of Minho (Portugal), following an internship at the Faculty of Medicine, University Complutense Madrid (Spain), under the guidance of Prof. J Regueiro. After graduating, HF joined the group of Prof. C van Blitterswijk and Prof. J de Boer at the University of Twente (Netherlands), where he successfully completed his PhD in 2009. His groundbreaking research during this period made significant contributions to the field of Bone Tissue Engineering by unraveling the biomaterial-driven molecular mechanisms governing the differentiation of human stem cells into osteoblasts. These pioneering findings were published in top-tier journals such as PNAS and Biomaterials. Continuing his academic journey, HF embarked on post-doctoral studies, where he established the use of high-throughput screening (HTS) technologies to identify and explore the role of small molecules in endothelial differentiation and function. In 2011, HF was invited to lead a new research group at the University of Twente, focusing on developing innovative translational technologies for tendon and ligament regeneration. During his tenure, HF provided mentorship to two Ph.D. students and one visiting Ph.D. student from Rutgers University (USA), as well as six MSc and six BSc students. The remarkable outcomes of their collaborative efforts resulted in the publication of seven peer-reviewed articles and the submission of a patent (P113734NL00). In 2014, HF joined the laboratory of Professor Lino Ferreira at the University of Coimbra (Portugal) where he directed his research towards two main areas: (i) the use of HTS platforms to discover miRNAs capable of modulating cell fate in the context of ageing & disease and (ii) engineering extracellular vesicles to deliver miRNAs in vivo. In 2020, HF received the prestigious “Individual Scientific Employment Stimuli” grant from the Portuguese Foundation of Science and Technology to further develop his research in the field of Molecular Bioengineering. In 2023, HF took up a position at the Multidisciplinary Institute of Ageing at the University of Coimbra, assuming the role of Principal Investigator and establishing his independent laboratory. His current research interests encompass (i) unravelling the mechanisms governing stem cell aging and (ii) developing therapeutic strategies capable of ameliorating or reversing this process. HF secured research funds exceeding €1.8M, and published 47 peer-reviewed manuscripts in journals such as PNAS, Biomaterials, and Molecular Therapy, accumulating over 2200 citations and achieving an h-index of 21 (Scopus). Additionally, HF has submitted two patents. HF is actively involved as a referee for several leading journals in the field of Bioengineering and as an Expert Evaluator for institutions such as the EU (Sklodowska-Curie fellowships; 2017-22), the French National Research Agency, the Dunhill Medical Trust, the Swiss National Science Foundation, Action Medical Research, and the Polish Science Foundation. HF's dedication to advancing the field is evident through his active participation as a Board Member (Secretary) of the Portuguese Society for Stem Cells and Cell Therapy since 2019. Since 2023, HF is elected member of the III-UC Scientific Council and MIA-UC.
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Identificação

Identificação pessoal

Nome completo
Hugo Agostinho Machado Fernandes
Data de nascimento
1977/10/16
Género
Masculino

Nomes de citação

  • Fernandes, Hugo
  • Hugo Machado Fernandes
  • Fernandes, H.A.M.

Identificadores de autor

Ciência ID
CE15-5259-CC1D
ORCID iD
0000-0002-4574-7648
Google Scholar ID
https://scholar.google.pt/citations?user=fzRUwicAAAAJ&hl=en
Researcher Id
H-6192-2014
Scopus Author Id
32667641200

Endereços de correio eletrónico

  • hugo.fernandes@uc.pt (Profissional)
  • h.fernandes@me.com (Pessoal)

Telefones

Telefone
  • 231249170 (Profissional)

Moradas

  • UC-Biotech, Biocant Parque; Nucleo 4, Lote 8, 3060-197, Cantanhede, Cantanhede, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Outras Ciências da Engenharia e Tecnologias
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C1) Utilizador elementar (A2) Utilizador proficiente (C1) Utilizador elementar (A2)
Formação
Grau Classificação
2013
Concluído
 Designing a lesson and a course (Outros)
Universiteit Twente, Países Baixos
2013
Concluído
 University Teaching Qualification (Pós-Graduação)
Universiteit Twente, Países Baixos
2013
Concluído
 Guidelines and legislation for clinical trials in human subjects (Outros)
Universiteit Twente, Países Baixos
2012
Concluído
 Time Management course (Outros)
Universiteit Twente, Países Baixos
2012
Concluído
 Testing and assessment (Outros)
Universiteit Twente, Países Baixos
2012
Concluído
 Supervising final projects (Outros)
Universiteit Twente, Países Baixos
2012
Concluído
 Policy of Education and course coordination (Outros)
Universiteit Twente, Países Baixos
2011
Concluído
 Certification program for Ingenuity Pathway Analysis (Outros)
QIAGEN Bioinformatics, Estados Unidos
2010 - 2010
Concluído
 Dutch course – Follow-up III (Outros)
Universiteit Twente, Países Baixos
2010
Concluído
 Analysis of microarray gene expression data (Outros)
Universiteit Leiden, Países Baixos
2009
Concluído
 Biomedical Engineering (Doutoramento)
Universiteit Twente, Países Baixos
"Instructive Elements for Bone Tissue Engineering" (TESE/DISSERTAÇÃO)
 N/A
2009
Concluído
 Intensive week Dutch Course (Outros)
Universiteit Twente, Países Baixos
2009
Concluído
 Dutch course – Follow-up I (Outros)
Universiteit Twente, Países Baixos
2009
Concluído
 Dutch course – Follow-up II (Outros)
Universiteit Twente, Países Baixos
2007
Concluído
 Presentation Skills course (Outros)
Universiteit Twente, Países Baixos
2007
Concluído
 Technical writing and Editing training program (Outros)
Universiteit Twente, Países Baixos
2005
Concluído
 Laboratory Animal Science (Outros)
Universiteit Utrecht, Países Baixos
2004
Concluído
 Safety and Occupational Health (Pós-Graduação)
Worfocus, Portugal
2002/03 - 2002/08
Concluído
 Erasmus Exchange Student (Outros)
Universidad Complutense de Madrid Facultad de Medicina, Espanha
 19/20
2002
Concluído
 Applied Biology (Licenciatura)
Universidade do Minho, Portugal
"Immunopathologies of T lymphocytes" (TESE/DISSERTAÇÃO)
 14/20
1998
Frequentou
 Systems Engineering and Computer Science (Licenciatura)
Universidade do Minho Escola de Engenharia, Portugal
"N/A" (TESE/DISSERTAÇÃO)
 N/A
1995/07/11
Concluído
 Natural Sciences (Ensino secundário)
Colégio Dom Diogo de Sousa, Portugal
"N/A" (TESE/DISSERTAÇÃO)
 N/A
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/07/01 - Atual Investigador principal (carreira) (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
(...)
2023/04 - 2024/06/30 Investigador principal (carreira) (Investigação) Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2020/11/16 - 2023/04 Investigador Auxiliar Convidado (carreira) (Investigação) University Coimbra - Faculty Medicine, Portugal
2018/11/17 - 2021/11 Investigador principal convidado (carreira) (Investigação) University Coimbra - Faculty Medicine, Portugal
2017/11/17 - 2018/11/16 Investigador Auxiliar Convidado (carreira) (Investigação) University Coimbra - Faculty Medicine, Portugal
2014/01/01 - 2017/11/16 Investigador Auxiliar (carreira) (Investigação) CNC.IBILI, Portugal
2011/09/01 - 2013/12/31 Investigador Auxiliar (carreira) (Investigação) Universiteit Twente, Países Baixos
2004/01/01 - 2004/09/01 Investigador (Investigação) Universidade do Minho, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/01/02 - Atual Vice-President Portuguese Society of Stem Cells and Cell Therapies Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2023/05 - Atual Member of the Scientific Council of III-UC Universidade de Coimbra, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2023/01 - Atual Member of Scientific Council MIA-Portugal Universidade de Coimbra, Portugal
Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2017/10 - 2019/10 National Coordinator - Science and Technology of Stem cells Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2009/02/01 - 2011/08/01 Postdoctoral Fellow Universiteit Twente, Países Baixos
2002/03/01 - 2002/08/01 Erasmus Exchange Student Universidad Complutense de Madrid Facultad de Medicina, Espanha
Projetos

Bolsa

Designação Financiadores
2023/03 - Atual miRNA-engineered EVs for the treatment of diabetic wounds
NA
Investigador responsável
Sociedade Portuguesa de Diabetologia
2015/07/01 - Atual Role of microRNAs in chondrogenesis of human mesenchymal stromal cells
TAS Breakthrough #116005004
Bolseiro de Integração na Investigação
Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Países Baixos
Concluído
2025/01/01 - 2026/06/30 “REVERSE - restoring beta cell function by engineering extracellular vesicles with microRNAs”
NA
Investigador responsável
Universidade de Coimbra, Portugal
Em curso
2022/07/01 - 2023/06/30 BIO-MED: Biomolecular Engineering of extracellular vesicles for Regenerative Medicine
AAC nº01/SAICT/2021 - Project #181228
Co-Investigador Responsável (Co-IR)
Programa Operacional Regional do Centro
Em curso
2021/11 - 2023/04 EV-Heart: cardioprotection and regeneration mediated by systemic administration of targeted miRNA-modulated extracellular vesicles
CEECIND/01880/2018
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2018/08 - 2021/08 Exo-Heart: cardiac protection and regeneration mediated by systemic administration of targeted exosomes
029919
 Fundação para a Ciência e a Tecnologia
Concluído
2017/06/01 - 2021/06/01 Towards personalized beta-cell mass imaging in type 2 Diabetes
95105008
Bolseiro de Integração na Investigação
ZonMw, Países Baixos
 ZonMw
2013/07 - 2015/06 Combinatorial approaches to promote cell survival - PROSURVIVAL
125994
Provided by PTCRIS: 125994
 Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2012/02/01 - 2016/02/01 Validation of bone marrow aspirate concentrator for reconstructive medicine
NA
Investigador responsável
Smith & Nephew, Estados Unidos
2012/02/01 - 2016/02/01 Advanced Tendon and Ligament Healing
NA
Investigador responsável
Smith & Nephew, Estados Unidos
Produções

Publicações

Artigo em boletim informativo
  1. Susana Simões; Fernandes, Hugo; Lino da Silva Ferreira. "Recent advances on non viral CRISPR nano formulations for brain delivery and clinical approaches", ARRIGE (Association for responsible research and innovation in genome editing Newsletter), 2021, https://www.arrige.org/wp-content/uploads/2021/10/ARRIGE_newsletter_issue4.pdf.
Artigo em revista
  1. Vilaça, Andreia; Jesus, Carlos; Lino, Miguel; Hayman, Danika; Emanueli, Costanza; Terracciano, Cesare M.; Fernandes, Hugo; de Windt, Leon J.; Ferreira, Lino. "Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells". Molecular Therapy - Nucleic Acids (2024): 102233. http://dx.doi.org/10.1016/j.omtn.2024.102233.
    Aceite para publicação • 10.1016/j.omtn.2024.102233
  2. Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S.. "POSEIDON: Peptidic Objects SEquence-based Interaction with cellular DOmaiNs: a new database and predictor". Journal of Cheminformatics 16 1 (2024): http://dx.doi.org/10.1186/s13321-024-00810-7.
    10.1186/s13321-024-00810-7
  3. Ramos Rego, Inês; Silvério, Daniela; Eufrásio, Maria Isabel; Pinhanços, Sandra Sofia; Lopes da Costa, Bruna; Teixeira, José; Fernandes, Hugo; et al. "TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status". Antioxidants 12 2 (2023): 381. http://dx.doi.org/10.3390/antiox12020381.
    10.3390/antiox12020381
  4. Vilaça, Andreia; de Windt, Leon J.; Fernandes, Hugo; Ferreira, Lino. "Strategies and challenges for non-viral delivery of non-coding RNAs to the heart". Trends in Molecular Medicine (2022): http://dx.doi.org/10.1016/j.molmed.2022.10.002.
    No prelo • 10.1016/j.molmed.2022.10.002
  5. Fernandes, Hugo; Zonnari, Alessandra; Abreu, Ricardo; Aday, Sezin; Barão, Marta; Albino, Inês; Lino, Miguel; et al. Autor correspondente: Fernandes, Hugo. "Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration". Molecular Therapy - Nucleic Acids 28 (2022): 307-327. http://dx.doi.org/10.1016/j.omtn.2022.03.018.
    10.1016/j.omtn.2022.03.018
  6. Esteves, Marta; Abreu, Ricardo; Fernandes, Hugo; Serra-Almeida, Catarina; Martins, Patrícia A.T.; Barão, Marta; Cristóvão, Ana Clara; et al. "MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease". Molecular Therapy (2022): http://dx.doi.org/10.1016/j.ymthe.2022.06.003.
    10.1016/j.ymthe.2022.06.003
  7. Ottaviani, L.; Juni, R.P.; de Abreu, R.C.; Sansonetti, M.; Sampaio-Pinto, V.; Halkein, J.; Hegenbarth, J.C.; et al. "Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells". Molecular Therapy (2022): http://dx.doi.org/10.1016/j.ymthe.2022.03.002.
    10.1016/j.ymthe.2022.03.002
  8. Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira. "High-throughput screening of nanoparticles in drug delivery". APL Bioengineering (2021): https://doi.org/10.1063/5.0057204.
    10.1063/5.0057204
  9. Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al. Autor correspondente: Fernandes, Hugo. "Exogenous loading of miRNAs into small extracellular vesicles". Journal of Extracellular Vesicles 10 10 (2021): http://dx.doi.org/10.1002/jev2.12111.
    Acesso aberto • 10.1002/jev2.12111
  10. Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino. Autor correspondente: Ferreira, Lino. "A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies". Methods (2020): http://dx.doi.org/10.1016/j.ymeth.2020.12.002.
    10.1016/j.ymeth.2020.12.002
  11. de Abreu, Ricardo Cerqueira; Fernandes, Hugo; da Costa Martins, Paula A.; Sahoo, Susmita; Emanueli, Costanza; Ferreira, Lino. "Native and bioengineered extracellular vesicles for cardiovascular therapeutics". Nature Reviews Cardiology 17 11 (2020): 685-697. http://dx.doi.org/10.1038/s41569-020-0389-5.
    10.1038/s41569-020-0389-5
  12. Pádua, Diana; Barros, Rita; Amaral, Ana Luísa; Mesquita, Patrícia; Freire, Ana Filipa; Sousa, Mafalda; Maia, André Filipe; et al. "A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin". Cancers 12 2 (2020): 495. http://dx.doi.org/10.3390/cancers12020495.
    10.3390/cancers12020495
  13. Rosa, Susana; Pitrez, Patrícia; Fernandes, Hugo; Ferreira, Lino. Autor correspondente: Fernandes, Hugo. "A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity". Current Protocols in Stem Cell Biology 50 1 (2019): http://dx.doi.org/10.1002/cpsc.93.
    10.1002/cpsc.93
  14. Othman, Ziryan; Fernandes, Hugo; Groot, Arjan J.; Luider, Theo M.; Alcinesio, Alessandro; Pereira, Daniel de Melo; Guttenplan, Alexander P.M.; Yuan, Huipin; Habibovic, Pamela. "The role of ENPP1/PC-1 in osteoinduction by calcium phosphate ceramics". Biomaterials 210 (2019): 12-24. http://dx.doi.org/10.1016/j.biomaterials.2019.04.021.
    10.1016/j.biomaterials.2019.04.021
  15. Honglin Chen; Danielle F. Baptista; Giuseppe Criscenti; João Crispim; Hugo Fernandes; Clemens van Blitterswijk; Roman Truckenmüller; Lorenzo Moroni. "From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation". Nanoscale 11 30 (2019): 14312-14321. https://doi.org/10.1039/C8NR10108F.
    10.1039/C8NR10108F
  16. Criscenti G; De Maria C; Longoni A; van Blitterswijk CA; Fernandes HAM; Vozzi G; Moroni L. "Soft-molecular imprinted electrospun scaffolds to mimic specific biological tissues.". Biofabrication (2018): http://europepmc.org/abstract/med/30024388.
    10.1088/1758-5090/aad48a
  17. Crispim JF; Fu SC; Lee YW; Fernandes HAM; Jonkheijm P; Yung PSH; Saris DBF. "Bioactive Tape With BMP-2 Binding Peptides Captures Endogenous Growth Factors and Accelerates Healing After Anterior Cruciate Ligament Reconstruction.". The American journal of sports medicine (2018): http://europepmc.org/abstract/med/30074814.
    10.1177/0363546518787507
  18. Ghebes, Corina Adriana; Groen, Nathalie; Cheuk, Yau Chuk; Fu, Sai Chuen; Fernandes, Hugo Machado; Saris, Daniel B.F.. Autor correspondente: Fernandes, Hugo Machado. "Muscle-Secreted Factors Improve Anterior Cruciate Ligament Graft Healing: An In Vitro and In Vivo Analysis". Tissue Engineering Part A 24 3-4 (2018): 322-334. http://dx.doi.org/10.1089/ten.tea.2016.0546.
    10.1089/ten.tea.2016.0546
  19. Ekwueme, Emmanuel C.; Mohiuddin, Mahir; Yarborough, Jazmin A.; Brolinson, P. Gunnar; Docheva, Denitsa; Fernandes, Hugo A. M.; Freeman, Joseph W.. "Prolotherapy Induces an Inflammatory Response in Human Tenocytes In Vitro". Clinical Orthopaedics and Related Research® 475 8 (2017): 2117-2127. http://dx.doi.org/10.1007/s11999-017-5370-1.
    10.1007/s11999-017-5370-1
  20. Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al. "High-throughput identification of small molecules that affect human embryonic vascular development.". (2017): http://europepmc.org/abstract/med/28348206.
    10.1073/pnas.1617451114
  21. Crispim, J.; Fernandes, H.A.M.; Fu, S.C.; Lee, Y.W.; Jonkheijm, P.; Saris, D.B.F.. "TGF-ß1 activation in human hamstring cells through growth factor binding peptides on polycaprolactone surfaces". Acta Biomaterialia 53 (2017): 165-178. http://dx.doi.org/10.1016/j.actbio.2017.01.066.
    10.1016/j.actbio.2017.01.066
  22. Romão, Joana; Barata, David; Ribeiro, Nelson; Habibovic, Pamela; Fernandes, Hugo; Mul, Guido. Autor correspondente: Fernandes, Hugo. "High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water". Environmental Pollution 220 (2017): 1199-1207. http://dx.doi.org/10.1016/j.envpol.2016.11.015.
    10.1016/j.envpol.2016.11.015
  23. Ghebes CA; Braham MV; Zeegers AV; Renard AJ; Fernandes H; Saris DB. Autor correspondente: Fernandes H. "Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation.". (2016): http://europepmc.org/abstract/med/27955656.
  24. Ghebes, Corina-Adriana; van Lente, Jéré; Post, Janine Nicole; Saris, Daniel B. F.; Fernandes, Hugo. Autor correspondente: Fernandes, Hugo. "High-Throughput Screening Assay Identifies Small Molecules Capable of Modulating the BMP-2 and TGF-ß1 Signaling Pathway". SLAS DISCOVERY: Advancing Life Sciences R&D 22 1 (2016): 40-50. http://dx.doi.org/10.1177/1087057116669346.
    10.1177/1087057116669346
  25. Ekwueme, Emmanuel C.; Shah, Jay V.; Mohiuddin, Mahir; Ghebes, Corina A.; Crispim, João F.; Saris, Daniël B.F.; Fernandes, Hugo A.M.; Freeman, Joseph W.. "Cross-Talk Between Human Tenocytes and Bone Marrow Stromal Cells Potentiates Extracellular Matrix Remodeling In Vitro". Journal of Cellular Biochemistry 117 3 (2015): 684-693. http://dx.doi.org/10.1002/jcb.25353.
    10.1002/jcb.25353
  26. Higuera, Gustavo A.; Fernandes, Hugo; Spitters, Tim W.G.M.; van de Peppel, Jeroen; Aufferman, Nils; Truckenmueller, Roman; Escalante, Maryana; et al. "Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo". Biomaterials 61 (2015): 190-202. http://dx.doi.org/10.1016/j.biomaterials.2015.05.017.
    10.1016/j.biomaterials.2015.05.017
  27. Ghebes, Corina Adriana; Kelder, Cindy; Schot, Thomas; Renard, Auke J.; Pakvis, Dean F. M.; Fernandes, Hugo; Saris, Daniel B.. "Anterior cruciate ligament- and hamstring tendon-derived cells: in vitro differential properties of cells involved in ACL reconstruction". Journal of Tissue Engineering and Regenerative Medicine 11 4 (2015): 1077-1088. http://dx.doi.org/10.1002/term.2009.
    10.1002/term.2009
  28. Le B; Fernandes H; Bouten C; Karperien M; van Blitterswijk C; de Boer J. "High throughput screening assay for the identification of compounds enhancing collagenous extracellular matrix production by ATDC5 cells.". (2015): http://europepmc.org/abstract/med/25604243.
    10.1089/ten.TEC.2014.0088
  29. Thakkar, Shraddha; Ghebes, Corina A.; Ahmed, Maqsood; Kelder, Cindy; van Blitterswijk, Clemens A.; Saris, Daniel; Fernandes, Hugo A. M.; Moroni, Lorenzo. "Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes". Biofabrication 5 2 (2013):
    10.1088/1758-5082/5/2/025003
  30. Barradas, Ana M. C.; Monticone, Veronica; Hulsman, Marc; Danoux, Charlene; Fernandes, Hugo; Birgani, Zeinab Tahmasebi; Barrere-de Groot, Florence; et al. "Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells". Integrative Biology 5 7 (2013): 920-931.
    10.1039/c3ib40027a
  31. Doorn, Joyce; Fernandes, Hugo A. M.; Le, Bach Q.; van de Peppel, Jeroen; van Leeuwen, Johannes P. T. M.; De Vries, Margreet R.; Aref, Zeen; et al. "A small molecule approach to engineering vascularized tissue". Biomaterials 34 12 (2013): 3053-3063.
    10.1016/j.biomaterials.2012.12.037
  32. Prins HJ; Fernandes H; Rozemuller H; van Blitterswijk C; de Boer J; Martens AC. "Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite and ß-tricalcium phosphate.". (2012): http://europepmc.org/abstract/med/23255230.
    10.1002/term.1681
  33. Barradas, Ana M.C.; Yuan, Huipin; van der Stok, Johan; Le Quang, Bach; Fernandes, Hugo; Chaterjea, Anindita; Hogenes, Marieke C.H.; et al. "The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice". Biomaterials 33 23 (2012): 5696-5705. http://dx.doi.org/10.1016/j.biomaterials.2012.04.021.
    10.1016/j.biomaterials.2012.04.021
  34. Barradas, Ana M.C.; Fernandes, Hugo A.M.; Groen, Nathalie; Chai, Yoke Chin; Schrooten, Jan; van de Peppel, Jeroen; van Leeuwen, Johannes P.T.M.; van Blitterswijk, Clemens A.; de Boer, Jan. "A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells". Biomaterials 33 11 (2012): 3205-3215. http://dx.doi.org/10.1016/j.biomaterials.2012.01.020.
    10.1016/j.biomaterials.2012.01.020
  35. Portalska, Karolina Janeczek; Leferink, Anne; Groen, Nathalie; Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan. "Endothelial Differentiation of Mesenchymal Stromal Cells". Plos One 7 10 (2012):
    10.1371/journal.pone.0046842
  36. Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D.. "'Smart' biomaterials and osteoinductivity". Nature Reviews Rheumatology 7 4 (2011): 1-1.
    10.1038/nrrheum.2010.210-c1
  37. Nandakumar, Anandkumar; Fernandes, Hugo; de Boer, Jan; Moroni, Lorenzo; Habibovic, Pamela; van Blitterswijk, Clemens A.. "Fabrication of Bioactive Composite Scaffolds by Electrospinning for Bone Regeneration". Macromolecular Bioscience 10 11 (2010): 1365-1373. http://dx.doi.org/10.1002/mabi.201000145.
    10.1002/mabi.201000145
  38. Fernandes, Hugo; Dechering, Koen; van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Mentink, Anouk; van Blitterswijk, Clemens; de Boer, Jan. "Effect of Chordin-Like 1 on MC3T3-E1 and Human Mesenchymal Stem Cells". Cells Tissues Organs 191 6 (2010): 443-452.
    10.1159/000281825
  39. Fernandes, Hugo; Mentink, Anouk; Bank, Ruud; Stoop, Reinout; van Blitterswijk, Clemens; de Boer, Jan. "Endogenous Collagen Influences Differentiation of Human Multipotent Mesenchymal Stromal Cells". Tissue Engineering Part a 16 5 (2010): 1693-1702.
    10.1089/ten.tea.2009.0341
  40. Liu, Jun; Barradas, Ana; Fernandes, Hugo; Janssen, Frank; Papenburg, Bernke; Stamatialis, Dimitrios; Martens, Anton; van Blitterswijk, Clemens; de Boer, Jan. "In Vitro and In Vivo Bioluminescent Imaging of Hypoxia in Tissue-Engineered Grafts". Tissue Engineering Part C-Methods 16 3 (2010): 479-485.
    10.1089/ten.tec.2009.0278
  41. Teixeira, S.; Fernandes, H.; Leusink, A.; van Blitterswijk, C.; Ferraz, M. P.; Monteiro, F. J.; de Boer, J.. "In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering". Journal of Biomedical Materials Research Part a 93A 2 (2010): 567-575.
    10.1002/jbm.a.32532
  42. Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D.. "Osteoinductive ceramics as a synthetic alternative to autologous bone grafting". Proceedings of the National Academy of Sciences of the United States of America 107 31 (2010): 13614-13619.
    10.1073/pnas.1003600107
  43. Fernandes, Hugo; Dechering, Koen; Van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Leusink, Anouk; Bank, Ruud; et al. "The Role of Collagen Crosslinking in Differentiation of Human Mesenchymal Stem Cells and MC3T3-E1 Cells". Tissue Engineering Part A 15 12 (2009): 3857-3867. http://dx.doi.org/10.1089/ten.tea.2009.0011.
    10.1089/ten.tea.2009.0011
  44. Siddappa, Ramakrishnaiah; Mulder, Winfried; Steeghs, Ilse; van de Klundert, Christine; Fernandes, Hugo; Liu, Jun; Arends, Roel; van Blitterswijk, Clemens; de Boer, Jan. "cAMP/PKA Signaling Inhibits Osteogenic Differentiation and Bone Formation in Rodent Models". Tissue Engineering Part A 15 8 (2009): 2135-2143. http://dx.doi.org/10.1089/ten.tea.2008.0512.
    10.1089/ten.tea.2008.0512
  45. Schop, Deborah; Janssen, Frank W.; van Rijn, Linda D.S.; Fernandes, Hugo; Bloem, Rolf M.; de Bruijn, Joost D.; van Dijkhuizen-Radersma, Riemke. "Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells". Tissue Engineering Part A 15 8 (2009): 1877-1886. http://dx.doi.org/10.1089/ten.tea.2008.0345.
    10.1089/ten.tea.2008.0345
  46. Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan. "Extracellular matrix and tissue engineering applications". Journal of Materials Chemistry 19 31 (2009): 5474-5484.
    10.1039/b822177d
  47. Siddappa, Ramakrishnaiah; Fernandes, Hugo; Liu, Jun; van Blitterswijk, Clemens; de Boer, Jan. "The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering.". Current stem cell research & therapy 2 3 (2007): 209-20.
    10.2174/157488807781696267
  48. Teixeira, S.; Fernandes, H.M.; De Boer, J.; Ferraz, M.P.; Monteiro, F.J.. "Mesenchymal stem cell proliferation and morphological analysis on interconnected macroporous structures". Key Engineering Materials 330-332 II (2007): 1129-1132. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846317063&partnerID=MN8TOARS.
Capítulo de livro
  1. Thakkar, Shraddha; Fernandes, Hugo; Moroni, Lorenzo. "Decellularized Extracellular Matrix Scaffolds for Cartilage Regeneration". In Cartilage Tissue Engineering, 133-151. Springer New York, 2015.
    10.1007/978-1-4939-2938-2_9
  2. Fernandes, Hugo; Roderick Beijersbergen; Lino Ferreira; Koen Dechering; Prabhas Moghe; Katharina Maniura-Weber. "Bioassay Development". In Materiomics: high-Throughput Screening of Biomaterial Properties. Cambridge University Press, 2013.
  3. Fernandes, Hugo; Frits Hulshof; Er Liu; Andrea Negro; Samy Gobaa; Matthias Lutolf; Prabhas Moghe. "High-content Imaging". In Materiomics: high-Throughput Screening of Biomaterial Properties. Cambridge University Press, 2013.
Poster em conferência
  1. Carlos Gaspar Jesus; Miguel Lino; Hugo Machado Fernandes; Lino da Silva Ferreira. "Scalable production of Extracellular Vesicles from Mesenchymal Stem/Stromal Cells using a Hollow Fiber Bioreactor". Trabalho apresentado em MOVE 2nd Symposium 08 – 11th October 2024, Belgrade, Serbia., 2024.
  2. Pinhanços, SS or Pinhanços, SM; Fernandes, Hugo. "Identification of microRNAs able to protect beta-cells from glucolipotoxicity using a High Throughput Screening approach". Trabalho apresentado em 3rd RESETageing Conference, 2023.
  3. João Teixeira Oliveira; Hugo Machado Fernandes. "Use of extracellular vesicles miRNAs as markers of diabetes reversion in metabolic surgery patients". Trabalho apresentado em International Diabetes Federation, 2023.
  4. Carlos Jesus; Fernandes, Hugo; Miguel LIno; Lino Ferreira. Autor correspondente: Fernandes, Hugo. "Scalable production of Extracellular Vesicles from Mesenchymal Stem/Stromal Cells using a Hollow Fiber Bioreactor". Trabalho apresentado em ETRS-SPCETC Joint Annual Meeting 2023, 2023.
  5. Sandra Mimoso; Fernandes, Hugo. Autor correspondente: Fernandes, Hugo. "Identification of miRNAs able to protect beta-cells from glucolipotoxicity using a high-throughput screening approach". Trabalho apresentado em ETRS-SPCETC Joint Annual Meeting 2023, 2023.
  6. Sandra Mimoso; Hugo Fernandes. Autor correspondente: Hugo Fernandes. "Identification of miRNAs able to protect beta-cells from glucolipotoxicity using a high-throughput screening approach". Trabalho apresentado em EASD - European Association for the study of diabetes, 2023.
  7. Marta Barao; Fernandes, Hugo. "Extracellular vehicles enriched with an endothelial cell pro-survival microRNA impacts skin tissue regeneration". Trabalho apresentado em XXVII School of pure and applied biophysics - Extracellular Vesicles: from biophysical to translational challenges, 2023.
  8. Sandra Mimoso; João Teixeira; Martin Gotthard; Jorge Santos; Lino Ferreira; John Jones; Fernandes, Hugo. Autor correspondente: Fernandes, Hugo. "High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death.". Trabalho apresentado em International Diabetes Federation - World Congress, 2022.
  9. Sandra Mimoso; João Teixeira; Martin Gotthard; Jorge Santos; Lino Ferreira; John Jones; Fernandes, Hugo. Autor correspondente: Fernandes, Hugo. "High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death.". Trabalho apresentado em Early Career Network Winter School; European Association for the study of obesity, 2022.
  10. Fernandes, Hugo; Alessandra Zonnari; Ricardo Abreu; Sezin Aday; Marta Barão; Ines Albino; Miguel Lino; et al. "Extracellular vehicles enriched with an endothelial cell pro- survival microrna impacts skin tissue regeneration". Trabalho apresentado em 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2022.
  11. Fernandes, Hugo; Ricardo Abreu; Miguel Lino; Cristiana Ramos; Clarissa Becher; Carlos Jesus; Paula Martins; et al. "Biomolecular engineering of extracellular vesicles with micrornas". Trabalho apresentado em 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2022.
  12. Carlos Jesus. "Urinary extracellular vesicles as a tool for Regenerative Medicine.". Trabalho apresentado em 11th International Meeting of the Portuguese Society for stem cells and cell therapies, 2019.
  13. Abreu, Ricardo. "Bioengineered extracellular vesicles for Regenerative Medicine". Trabalho apresentado em Ageing: models, mechanisms and therapies, 2019.
  14. Abreu, Ricardo. "Extracellular Vesicle Engineering: modulation of non-coding RNA content". Trabalho apresentado em EMBO advanced course (Germany), 2018.
  15. Carlos Jesus. "Isolation and characterisation of urinary extracellular vesicles for Regenerative Medicine:". Trabalho apresentado em 1st Meeting on Vesicular Biology, 2018.
  16. Crispim, João F.. "Purification of platelet-rich plasma with peptide-functionalized microspheres". Trabalho apresentado em Orthopaedic Research Society Annual Meeting (USA), 2018.
  17. Lucienne Vonk. "microRNA-induced chondrogenic differentiation of mesenchymal stem cells". Trabalho apresentado em TERMIS-EU (Switzerland), 2017.
  18. Lucienne Vonk. "microRNA-induced chondrogenic differentiation of mesenchymal stroll cells". Trabalho apresentado em Orthopaedic Research Society Annual Meeting (USA), 2017.
  19. Crispim, João F.. "Use of synthetic peptides for the immobilisation of growth factors in wound healing". Trabalho apresentado em 9th International Meeting of the Portuguese Society for stem cells and cell therapies, 2015.
  20. Ekwueme, Emmanuel C.. "Proliferative therapy-induced changes in the cellular response of human tenocytes". Trabalho apresentado em Biomedical Engineering Society (BMES) annual meeting (USA), 2015.
  21. Ghebes, Corina Adriana. "accelerating ACL repair by understanding cellular communication in soft tissue to bone healing". Trabalho apresentado em 9th International Meeting of the Portuguese Society for stem cells and cell therapies, 2015.
  22. Ekwueme, Emmanuel C.. "Single-walled carbon nanotubes modulate tendon biomechanics and tenocyte cellular response:". Trabalho apresentado em TERMIS World Congress (USA), 2014.
  23. Criscenti G. "Realization of a soft-MI electrospun scaffold for tissue engineering applications". Trabalho apresentado em TERMIS-EU meeting (Italy), 2014.
  24. Ghebes, Corina-Adriana. "Accelerating ACL repair by understanding cellular communication in soft tissue to bone healing". Trabalho apresentado em Orthopaedic Research Society Annual Meeting (USA), 2014.
  25. Othman, Ziryan. "A proteomics approach to understand the role of calcium phosphate ceramics in bone regeneration". Trabalho apresentado em Netherlands Society for Biomaterials and Tissue Engineering (NBTE) Annual Meeting, 2014.
  26. Ivan Moldero. "Engineering stem cell distribution on 3D scaffolds influences cell activity". Trabalho apresentado em TERMIS-EU meeting (Italy), 2014.
  27. Vazão Helena. "Assessment of embryonic vascular toxicity by pluripotent stem cell-derived arterial endothelial cells on a microfluidic system". Trabalho apresentado em European Conference on Biomaterials,, 2013.
  28. Ghebes, Corina Adriana. "Hamstring tendon-derived cells, a cell source for anterior cruciate ligament reconstruction". Trabalho apresentado em Advances in Tissue Regeneration, November 2013 (Netherlands), 2013.
  29. Fernandes, Hugo. "Cell sources for anterior cruciate ligament reconstruction". Trabalho apresentado em 3th TERMIS World Congress (Austria), 2012.
  30. Fernandes, Hugo. "hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells". Trabalho apresentado em 3th TERMIS World Congress (Austria), 2012.
  31. Fernandes, Hugo. "hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells". Trabalho apresentado em Cell Symposia: Angiogenesis, metabolic regulation and cancer biology, Belgium., 2012.
  32. Le, Bach Q.. "High-throughput screening assay for the identification of compounds enhancing collagenous extracellular matrix production by ATDC5 cells". Trabalho apresentado em 21th conference of the Netherlands Society for Biomaterials and Tissue Engineering (Netherlands), 2012.
  33. Fernandes, Hugo. "human mesenchymal stromal cells as pro-angiogenic drug release systems". Trabalho apresentado em 4th International Angiogenesis Meeting, The Netherlands., 2011.
  34. Spitters, Tim W.G.M.. "The importance of gradients in articular cartilage". Trabalho apresentado em TERMIS-EU (Spain), 2011.
  35. Spitters, Tim W.G.M.. "Mimicking the knee joint, validation of a joint simulator". Trabalho apresentado em BMM/TerM Annual Meeting (Netherlands), 2011.
  36. Doorn, Joyce. "Hypoxia mimics as a tool to train human mesenchymal stroll cells for cell therapy applications". Trabalho apresentado em International Society for Cell Therapy (Netherlands), 2011.
  37. Portalska, Karolina Janeczek. "Mesenchymal stromal cells as a cell source in peripheral vascular disease treatment". Trabalho apresentado em STW Annual Congress (Netherlands), 2010.
  38. Barradas, Ana. "calcium phosphate ceramic particles accelerate osteogenesis of bone marrow cells". Trabalho apresentado em TERM SmartMix meeting (Netherlands), 2010.
  39. Portalska, Karolina Janeczek. "mesenchymal stem cells as potential sourcee for endothelial progenitors". Trabalho apresentado em Netherlands Society for Biomaterials and Tissue Engineering (NBTE) Annual Meeting, 2009.
  40. Fernandes, Hugo. "Investigating the role of collagen in osteogenic differentiation of human mesenchymal stem cells". Trabalho apresentado em TERMIS EU Meeting, Portugal, 2008.
  41. Fernandes, Hugo. "Investigating the role of the extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells". Trabalho apresentado em International bone and mineral research society workshop, Switzerland., 2008.
  42. Fernandes, Hugo. "Investigating the role of extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells". Trabalho apresentado em 17th conference of the Netherlands Society for Biomaterials and Tissue Engineering, The Netherlands., 2008.
  43. Sandra Teixeira. "in vitro and in vivo response of human mesenchymal stem cells to macroporous and interconnected ceramic scaffolds for bone tissue engineering". Trabalho apresentado em 8th World Biomaterials Congress (Netherlands), 2008.
  44. Sanne Both. "Bone tissue engineering in a rat cranial size defect with embryonic stem cells:". Trabalho apresentado em TERMIS-EU (United Kingdom), 2007.
  45. Prins HJ. "Bioluminescent imagineg (BLI) for in vivo tracing of human mesenchymal stem cell-based bone tissue engineering". Trabalho apresentado em TERMIS-EU (Netherlands), 2006.
  46. Prins HJ. "Bioluminescent imaging (BLI) for in vivo tracing of human mesenchymal stem cell-based bone tissue engineering". Trabalho apresentado em Netherlands Society for Biomaterials and Tissue Engineering Annual Meeting (Netherlands), 2006.

Propriedade Intelectual

Patente
  1. Fernandes, Hugo; Ferreira, L; Vazão, H. 2016. "Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition system, kit and uses therefore".
Pedido provisório de patente
  1. 2015. "Functionalization of biopolymers with growth factor-binding peptides".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/28 High-throughput screening identifies miRNAs capable of rescuing beta cells from glucolipotoxicity Biomanufacturing without borders
Instituto Superior Técnico (Lisbon, Portugal)
2024/10/28 “Células estaminais: os super-heróis da regeneração (mas até eles envelhecem)” - within the activities of Stem Cell Awareness day. Presentation for high-school students from agrupamento de Escolas Lima de Faria. Stem Cell Awareness Day
Ciência Viva and Portuguese Society Stem Cells and Cell Therapy (Cantanhede, Portugal)
2024/10/23 Advanced Cell Technology - brief presentation on stem cells and cell technologies for different groups of students (High-School to University) followed by guided laboratory visit Biocant Open Day 2024
Biocant Parque (Cantanhede, Portugal)
2024/09/27 Advanced Cell Technology CIBB Innovative Therapies Annual Meeting
CIBB (Portugal)
2024/07/28 “Ageing and Stem cells" - event organised during Expofacic 2024. Hands on experiments and seminars on the hallmarks of ageing and stem cells in Regenerative Medicine. Expofacic 2024
Câmara Municipal Cantanhede (Portugal)
2024/05/10 Multidisciplinary Institute of Ageing (MIA-Portugal) Startup Capital Summit
University Coimbra (Coimbra, Portugal)
2024/04/27 Células estaminais: os mágicos dentro de nós! Escola Ciência Viva
UC Exploratório (Coimbra)
2023/09/29 Unlocking the regenerative potential of extracellular vesicles: bioactivity enhancement through miRNA modulation Groningnen – Jena Aging Meeting (G-JAM) 2023
ERIBA, University Groningen (Groningen, Países Baixos)
2023/08/03 Medicina Regenerativa e o envelhecimento: A jornada da vida - The lecture was delivered to students attending "Senior University" and other attendants of Expofacic 2023 (the biggest Fair in the Center Region of Portugal). Expofacic 2023
Expofacic (Cantanhede, Portugal)
2023/03/24 Stem Cells - a lecture for Primary School students
Rómulo Centro de Ciência Viva (Coimbra)
2023/03/17 miRNAs que aumentam a sobrevivência e proliferação de células beta estão alterados em doentes diabéticos submetidos a cirurgia bariátrica (BEST ORAL PRESENTATION) 19º Congresso Português de Diabetes
Portuguese Society Diabetology
2023/03 Stem Cells - definition and applications Course Biotecnologia IEC
Colégio Nossa Senhora Assunção (Anadia)
2023/02/08 Extracellular vesicles: biomarkers and Regenerative Medicine applications
Centro Hospitalar e Universitário Coimbra (Serviço Nefrologia)
2022/12/07 Engineering extracellular vesicles for Regenerative Medicine applications Ageing Without Borders
SPCE-TC and Universidade Algarve (Faro, Portugal)
2022/11 Engineering Extracellular Vesicles for Regenerative Medicine applications CIBB Innovative Therapies Annual Meeting
CIBB (Portugal)
2022/10/13 Células estaminais e seus derivados: a fonte da juventude mais perto de si! Online presentations to high school students explaining what are stem cells and their applications. The following schools participated in the event: Agrupamento de Escolas do Fundão (Fundão) and Escola Secundária Morgado de Mateus (Vila Real) Dia Mundial células estaminais
Ciência Viva (Portugal)
2022/09 REGENERAÇÃO DE TECIDOS E FONTE DA JUVENTUDE - NA FARMÁCIA MAIS PRÓXIMA! Ciência às seis
Rómulo - Centro Ciência Viva Universidade de Coimbra (Coimbra, Portugal)
2022/03/12 miRNAs e vesículas extracelulares: uma nova terapia no tratamento do síndrome metabólico, 18th Congresso Português de diabetes
Sociedade Portuguesa Diabetes
2022 High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death Early Career Network Winter School
European Association for the study of obesity (Espanha)
2022 High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death International Diabetes Conference World Congress
International Diabetes Foundation (Portugal)
2021/10/25 Science and Stem Cells. Seminars about science and stem cells organized at Centro Escolar Cantanhede. During one week (1h/day) I had the chance to present our work and discuss with the students science and cell biology Science and Stem cells
Centro Escolar Cantanhede (Cantanhede)
2021/10/13 Stem Cell Seminar Celebrations Stem Cell Day 2021
Escola Secundária Infanta D. Maria (Coimbra)
2021/10/13 Stem Cell Seminar
Escola Básica da Ponte das Três Entradas (São Sebastião Feira)
2021/09/14 microRNA-modulated extracellular vesicles for Regenerative Medicine applications 1st Meeting Portuguese Society Extracellular Vesicles
I3S (Portugal)
2021/09/06 miRNA-engineered extracellular vesicles for Regenerative Medicine applications 31st Conference European Society Biomaterials
ESB (Porto, Portugal)
2021/06/10 miRNA-modified extracellular vesicles for wound regeneration 55th Anual Scientific Meeting
European Society for Clinical Investigation
2021/06/10 Extracellular vesicles as lncRNA-H19 carriers to the cardiovascular system Presented by Andreia Vilaça 55th Anual Scientific Meeting
European Society for Clinical Investigation
2020/12 Non-coding RNA-engineered extracellular vesicles for cardiac regeneration, 1st Workshop of the Portuguese Network on Extracellular Vesicles
Portuguese Network on Extracellular Vesicles (Online, Portugal)
2020/11/06 Harnessing the power of extracellular vesicles for wound regeneration 11th International Congress on Skin Ageing & Challenges 2020
(Porto (Virtual Meeting), Portugal)
2019/11 Diálogos com cientistas - Colégio Nossa Senhora Assunção (Anadia) Lecture with high-school students about stem cells and cardiovascular diseases
2019/10/11 High-content screening identifies pro-survival microRNas 11th International Meeting of the Portuguese Society for stem cells and cell therapies
Faculty Pharmacy Lisbon (Portugal)
2019/05 Human cardiac stem cell therapy PhD Program in Health Sciences
Faculty Medicine, University Coimbra
2019/04/13 Tailoring Biomaterials for Tissue Engineering Seminar Master Course in Pharmaceutical Biotechnology
Faculty of Pharmacy, University Coimbra (Portugal)
2019/04 “Regenerative Medicine: from the bench to the bedside and stem cells and drug screening” Course on Advanced Therapies, PhD Program in Experimental Biology and Biomedicine
Center Neuroscience and Cell Biology (Portugal)
2019/04 Tailoring Biomaterials for Tissue Engineering” Master in Pharmaceutical Biotechnology
Faculty of Pharmacy, University Coimbra (Portugal)
2018 High-content screening identifies pro-survival microRNAs 29th Annual Meeting of the European Society of Biomaterials
European Society Biomaterials (Países Baixos)
2018 Smart technologies to enable tissue regeneration IV National Meeting Biotechnology
Instituto Politécnico Coimbra (Portugal)
2018 CardioSTem Project MIT Portugal Annual Conference
(Portugal)
2018 Identification of pro survival microRNAs Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2018 Stem Cells and Regenerative Medicine Invited
University Aveiro (Portugal)
2017 High-throughput screening identifies pro-survival microRNas 10th International Meeting of the Portuguese Society for stem cells and cell therapies
(Portugal)
2017 From a medical problem to a product: new avenues in the treatment of skeletal disorders III Ciclo de Conferências em Biotecnologia Medicinal e Farmacêutica
Universidade Beira Interior (Portugal)
2017 Cell therapies for cardiac repair: role of microRNAs on cell survival Stem Cell Symposium
Portuguese Society for stem cells and cell therapies (Portugal)
2017 Identification of microRNAs capable of enhancing cell survival: Heart Without Borders
(Portugal)
2017 Identification of microRNAs capable of enhancing cell survival Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2017 Stem cells and drug screening MIT-Portugal, PhD Program Lectures
Instituto Superior Técnico - Universidade Lisboa (Portugal)
2017 Identification of microRNAs capable of enhancing cell survival Department of Physiology and cardiothoracic surgery, Faculty Medicine, University Porto
University Porto (Portugal)
2017 Capturing endogenous growth factors through synthetic peptides to enhance healing of tendons and ligaments Orthopaedic Research Society
Orthopaedic Research Society (Estados Unidos)
2016 Cell therapies for cardiac repair: role of microRNAs on cell survival Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2016 High-content screening identifica pro-survival microRNAs Institutional Seminars CNC
CNC.IBILI (Portugal)
2016 Identification of pro-survival microRNAs to improve cell survival Centro Hospitalar Universidade Coimbra
(Portugal)
2016 Stem cells and Drug Screening MIT-Portugal; PhD Program Lecturer
Instituto Superior Técnico, Universidade Lisboa (Portugal)
2015 a small molecule approach to engineering vascularised tissue th International Meeting of the Portuguese Society for stem cells and cell therapies
Portuguese Society for stem cells and cell therapies (Portugal)
2015 Stem cells and cell-material interactions Lecture Master Degree Biomedical Engineering
University Aveiro (Portugal)
2015 Stem cells and drug screening MIT-Portugal; PhD Program Lecture
Instituto Superior Técnico, Universidade de Lisboa (Portugal)
2015 Bioengineering strategies to modulate stem cell fate Institutional Seminar
CNC.IBILI (Portugal)
2015 Stem Cells and Clinical Applications: are we doing it right? UC-Biotech Seminars
CNC.IBILI (Portugal)
2015 ways to enhance musculoskeletal repair MIRA Biomedical technology and technical medicine day
University Twente (Países Baixos)
2014 Use of synthetic peptides for the delivery of growth factors for tendon/ligament healing TERMIS World Congress (USA)
TERMIS (Estados Unidos)
2014 Engineering stem cell distribution on 3D scaffolds influences cell activity TERMIS-EU meeting
TERMIS (Itália)
2014 Cross-talk between human tenocytes and bone marrow stroll cells potentiates extracellular matrix remodelling in vitro: TERMIS World Congress (USA)
TERMIS (Estados Unidos)
2014 Bio-instructive approach to accelerate ligament/tendon healing: Netherlands Society for Biomaterials and Tissue Engineering (NBTE) Annual Meeting
Netherlands Society for Biomaterials and Tissue Engineering (Países Baixos)
2014 Assessment of embryonic vascular toxicity by pluripotent stem cell-derived arterial endothelial cells on a microfluidic system TERMIS-EU meeting
TERMIS (Itália)
2013 Enabling technologies to control cell fate Invited Seminar Ferreira Lab
(Portugal)
2013 Tenogenic response of bone marrow stromal cells and tenocyte co-cultures Netherlands Society for Biomaterials and Tissue Engineering Annual Meeting (NBTE)
Netherlands Society for Biomaterials and Tissue Engineering (Países Baixos)
2013 characterisation of hamstring tendon-derived cells and their crosstalk with neighbouring cell types involved in embryonic development of tendons Netherlands Society for Biomaterials and Tissue Engineering Annual Meeting (NBTE)
Netherlands Society for Biomaterials and Tissue Engineering
2012 A novel player in angiogenesis Invited Seminar Dankers Lab
Technical University of Eindhoven (Países Baixos)
2011 topographical library to control stem cell fate 3rd COST TD0903 meeting
(Roménia)
2011 human mesenchymal stromal cells as pro-angiogenic releasing systems 4th International Conference on Tissue Engineering
(Grécia)
2011 A novel player in angiogenesis Invited Lecture Ferreira Lab
(Portugal)
2011 Training mesenchymal stromal cells for tissue engineering applications University Munich Seminars
(Alemanha)
2009 Hidden talents of stem cells World Congress on Regenerative Medicine
(Alemanha)
2008 Role of collagen cross linking in osteogenic differentiation: 8th World Biomaterials Congress
(Países Baixos)
2007 potential application of extracellular matrix proteins to control osteogenic differentiation of human mesenchymal stem cells 16th conference of the Netherlands Society for Biomaterials and Tissue Engineering
(Países Baixos)
2007 potential application of extracellular matrix proteins to control osteogenic differentiation of human mesenchymal stem cells: 17th Annual meeting of the Dutch Society for Calcium and bone metabolism
(Países Baixos)
2006 Role of extracellular matrix on osteogenic differentiation 5th conference of the Netherlands Society for Biomaterials and Tissue Engineering
(Países Baixos)
2006 Role of extracellular matrix on osteogenic differentiation 16th Annual Meeting of the Dutch Society for Calcium and Bone metabolism
(Países Baixos)
2006 Bone tissue engineering in a rat cranial critical defect with embryonic stem cells Dutch Society for Biomaterials and Tissue Engineering
Dutch Society for Biomaterials and Tissue Engineering (Países Baixos)
2003 Career options 5th Meeting of Applied Biology
Universidade Minho (Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2021/01 - Atual Engineering extracellular Vesicles to enhance wound healing (PhD Marta Barão)
Coorientador
2020/03 - Atual Urinary extracellular vesicles as modulators of endothelial and beta-cell function in Type 2 diabetes (PhD Sandra Mimoso)
Orientador
2019/12 - Atual Cardioprotection and regeneration mediated by systemic administration of targeted extracellular vesicles (PhD Carlos Jesus)
Coorientador
2023/09/01 - 2024/07/31 Exploring the role of miRNAs in wound healing and regenerative Medicine
Orientador
 Master Molecular & Cellular Biology - Biomedicine (Mestrado)
Universidade de Coimbra, Portugal
2016/09 - 2022/10 Targeting the heart: Extracellular vesicles and beyond (PhD Andreia Vilaça)
Coorientador
Universidade de Coimbra, Portugal

Universiteit Maastricht, Países Baixos
2022/03 - 2022/08 miRNA-engineered extracellular vesicles to improve skin wound healing (MSC Andrea Carolina Larrea)
Orientador
Università degli Studi del Piemonte Orientale Amedeo Avogadro, Itália
2022/02 - 2022/07 Modulation of Extracellular Vesicles for Regenerative Medicine (BSc Tomás Coimbra)
Orientador
 Lic. Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra, Portugal
2018 - 2022/02/21 Extracellular Vesicles as Platforms for Therapeutic microRNA delivery (PhD Ricardo Abreu)
Coorientador
Universiteit Maastricht, Países Baixos

Universidade de Coimbra, Portugal
2018/09 - 2020/03 Urine extracellular vesicles: a promising tool for Regenerative Medicine (MSc Inês Morais)
Orientador
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/09 - 2020/02 Towards personalised beta-cell mass imaging in type 2 diabetes (Research Assistant Sandra Mimoso)
Orientador
CNC.IBILI, Portugal
2018/09 - 2019/09 Uncover the mechanism behind miRNA function on cell survival (MSc Marta Barão)
Orientador
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - 2019 High-Throughput screening for extracellular vesicle content modulation for cardiovascular application (MSc Clarissa Becher)
Orientador
 Master
Georg-August-Universität Göttingen Universitätsmedizin, Alemanha
2018/02 - 2018/09 Mechanism of action of pro-survival microRNAs (Research Assistant - Inês Albino)
Orientador
CNC.IBILI, Portugal
2018/01 - 2018/09 Towards personalised beta-cell mass imaging in type 2 diabetes (Research Assistant Ana Branco)
Orientador
CNC.IBILI, Portugal
2018 - 2018 Urine extracellular vesicles: waste or a powerful tool? (MSc Carlos Jesus)
Orientador
Universidade de Coimbra, Portugal
2014/04 - 2017/09 Improving hematopoietic stem cell expansion using small molecules (Postdoctoral Fellowship Ana Barradas)
Orientador
 Postdoctoral Fellow, FCT Scholarship: SFRH/BPD/97286/2013 (Outra)
CNC.IBILI, Portugal
2017 - 2017 The role of miRNAs on cell survival (MSc Cátia Seabra)
Orientador
Universidade de Coimbra, Portugal
2013/07 - 2016/12 Functionalized surfaces for ligament tissue engineering (PhD João Crispim)
Orientador
Universiteit Twente, Países Baixos
2012/03 - 2016/09 Means of accelerating tendon graft healing after ACL reconstruction (PhD Corina Ghebes)
Orientador
Universiteit Twente, Países Baixos
2016 - 2016 Identification of microRNAs to promote cell survival for the treatment of ischemic diseases (MSc Carolina Santos)
Orientador
Universidade de Coimbra, Portugal
2015 - 2015 Optimizing an high-throughput screening assay for hematopoietic stem cell expansion in co-culture with Wharton´s Jelly mesenchymal stem cells (BSc Beatriz Martins)
Orientador
Universidade de Coimbra, Portugal
2013/09 - 2014/02 Non-surgical tissue engineering approaches to sub-failure ligament and tendon injury repair (PhD Emmanuel Ekwueme)
Coorientador
Rutgers The State University of New Jersey, Estados Unidos
2014 - 2014 Functionalized surfaces stimulating tendon/ligament healing by activation of the TGFb1 signalling (MSc Joyce Mulder)
Orientador
Universiteit Twente, Países Baixos
2014 - 2014 High-throughput screening to identify BMP-2 mimicking drugs (BSc Stijn t´Groen)
Orientador
Universiteit Twente, Países Baixos
2014 - 2014 Screening for small molecules that mimic TGF-b activation (BSc Jere van Lente)
Orientador
Universiteit Twente, Países Baixos
2013 - 2014 Bioassay development to identify pro-survival and pro-angiogenic compounds (MSc Thijs Beuving)
Orientador
Universiteit Twente, Países Baixos
2013 - 2014 New technologies for the isolation and priming of bone marrow cells (MSc Maaike Braham)
Orientador
Universiteit Twente, Países Baixos
2013 - 2014 High-throughput screening for tendon and ligament healing (MSc Tânia Barata)
Orientador
Universiteit Twente, Países Baixos

Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/09 - 2013/10 Tendon and Ligament Engineering (Postdoctoral Fellow Carlo Rossi)
Orientador
 Postdoctoral Fellow (Outra)
Universiteit Twente, Países Baixos
2013 - 2013 Crosstalk between mesenchymal stem cells and muscle, cartilage and bone cells in co-culture (BSc Robert Wisse)
Orientador
Universiteit Twente, Países Baixos
2013 - 2013 Influence of cell shape on cell fate decision (BSc Mariana Silva)
Orientador
Universiteit Twente, Países Baixos

Universidade do Minho, Portugal
2013 - 2013 Characterization of hamstring and anterior cruciate ligament cells (BSc Thomas Schot)
Orientador
Universiteit Twente, Países Baixos
2012 - 2012 The effect of cell shape on cell fate (MSc Hugo Moonen)
Orientador
Universiteit Twente, Países Baixos
2012 - 2012 Characterization of anterior cruciate ligament derived cells (BSc Cindy Kelder)
Orientador
Universiteit Twente, Países Baixos
2011 - 2011 The power of extracellular matrix (MSc Shraddha Thakkar)
Coorientador
Universiteit Twente, Países Baixos
2010 - 2010 Endothelial differentiation of mesenchymal stem cells (MSc Nathalie Groen)
Coorientador
Universiteit Twente, Países Baixos
2008 - 2008 Relation between hMSCs diffreentiation, cell shape and focal adhesion assembly (MSc Karolina Janeczek)
Coorientador
2007 - 2007 The effect of extracellular matrix recombinant proteins on osteogenic differentiation of human mesenchymal stem cells (BSc Monique Slijp)
Coorientador
Universiteit Twente, Países Baixos

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2015 - Atual Organisation of the weekly Seminars at UC-Biotech (2015)
Seminário (Membro da Comissão Organizadora)
 Universidade de Coimbra, Portugal
2001 - Atual Organisation of the 3rd Meeting of Applied Biology. Contributed to the outline of the meeting. (2001)
2023/10/10 - 2033/10/13 European Tissue Repair Society (ETRS) - Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC) joint annual meeting. This was the first joint meeting between the two Societies and it was an opportunity to exchange knowledge and ideas and to create new opportunities. We gathered ~200 people in Coimbra. (2023/10/10 - 2023/10/13)
Conferência (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal

Universidade de Coimbra, Portugal
2024/06/12 - 2024/06/12 Stem Cells - my team went to a pre-school (3-6 years old - Centro Escolar Cantanhede) to introduce some basic cell biology concepts and to explore the human body using histological sections of different organs systems. During 2h, we engaged with 20 students and teachers and discuss topics such as: what is a scientist, how do scientists work, what are stem cells, what type of cells do we have in our body, how cells grow and divide and much more... (2024/06/12 - 2024/06/12)
Outro
 Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2024/05/27 - 2024/05/29 The 2nd MIA-Portugal Ageing Spring School offers an opportunity to gain knowledge into the latest scientific trends in Ageing. The 3-day program features discussions with leading Ageing experts, fostering an international networking environment, and providing a platform to share groundbreaking results. The event will be held at Coimbra, an UNESCO World Heritage location. (2024/05/27 - 2024/05/29)
Conferência (Membro da Comissão Organizadora)
 Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2021/10/13 - 2021/10/13 Organization of the Stem Cell Day - together with other scientists we organized seminars at different schools in the Center Region of Portugal. (2021/10/13 - 2021/10/13)
Seminário (Presidente da Comissão Organizadora)
 Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2021/09/17 - 2021/09/17 3rd Retreat of CIBB's Innovative Therapies Area. Annual meeting organized by CIBB thematic strand Innovative Therapies led by Lino Ferreira. The goal is to get together, share the latest scientific achievements, get to know new members and socialize in an informal manner. (2021/09/17)
Encontro (Membro da Comissão Organizadora)
 Centre for Innovative Biomedicine and Biotechnology, Portugal
2021 - 2021 Symposium "Extracellular Vesicles for Tissue Regeneration". I proposed the symposium and invited the Keynote speaker, Professor Eduardo Marban, Director, Cedars-Sinai Heart Institute (USA). (2021)
Simpósio (Presidente da Comissão Organizadora)
 Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2020/01/16 - 2020/01/16 Organisation of an in-site visit to high school students (Escola Secundária Moimenta da Beira). I delivered a lecture on stem cells and organised the visit to the different laboratories. (2020/01/16 - 2020/01/16) CNC.IBILI, Portugal
2019/10/25 - 2019/10/25 Organisation of an in-site visit to high school students (Colégio Nossa Senhora Assunção, Anadia). I delivered a lecture about stem cells and organised the visit to the different laboratories. (2019/10/25)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2023/03 - Atual 6º Meetup Digital Health Portugal: Biobanks
Conferência
 6º Meetup Digital Health Portugal: Biobanks
2022/10/27 - Atual The Bioengineering - One Health Alliance in 2050: A One-Day voyage into the Future. Symposium with experts in Bioengineering to discuss the global challenges for 2050, particularly the ones requiring an interdisciplinary approach, involving social sciences, ethics, biology, medicine, and engineering. The aim was to break artificial boundaries between scientific domains, and adopting the concept of One Health, perceived as the holistic view on Health, in its components of Human Health, Animal Health and Environmental Health.
Simpósio
 The Bioengineering - One Health Alliance in 2050: A One-Day voyage into the Future
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/01 - Atual Research in higher education: How and what for? A meeting organised by the General Council University of Coimbra to discuss Research in Higher Education.
Encontro
 Research in higher education: How and what for?
2021/06/11 - Atual The first meeting of the consortium RESETageing, an EU-financed Twinning project with the University of Groningen and University of Maastricht (The Netherlands), and University Newcastle (UK).
Conferência
 1st RESETageing Conference
Universidade de Coimbra, Portugal
2019/02/27 - Atual diálogos com cientistas - seminar about stem cells and cell therapy
Seminário
 Cardiovascular Diseases and cell therapy
Escola Secundária Oliveira Bairro, Portugal
2019/02/22 - Atual Conferencias na Escola - Engagement with high school students.
Seminário
 Conferências na Escola
Escola Secundária Marques Castilho, Portugal
2019 - Atual Outreaching activity for High-school students and professors.
Seminário
 Células estaminais e Medicina Regenerativa
Instituto de Educação e Cidadania, Portugal
2018 - Atual 1st Meeting on Vesicular Biology
Encontro
 1st Meeting on Vesicular Biology
2017 - Atual Diálogos de Verão com cientistas
Mesa-redonda
 Doenças Cardiovasculares
Instituto de Educação e Cidadania, Portugal
2016 - Atual Mês da Ciência
Simpósio
 Células Estaminais e Terapias Celulares
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2016 - Atual Curso avançado de células estaminais
Seminário
 Curso avançado de células estaminais
Instituto de Educação e Cidadania, Portugal
2016 - Atual 1st Meeting on Biomedical Research
Encontro
 1st Meeting on Biomedical Research
2015 - Atual Curso avançado de células estaminais
Seminário
 Curso avançado de células estaminais
Instituto de Educação e Cidadania, Portugal
2013 - Atual Advances in Tissue Regeneration
Simpósio
 Advances in Tissue Regeneration, November 2013, The Netherlands.
2012 - Atual Poster Presentation: Cell sources for anterior cruciate ligament reconstruction
Conferência
 TERMIS International, Austria.
Universiteit Twente, Países Baixos
2012 - Atual Poster Presentation: hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells. (Travel Award)
Conferência
 TERMIS International, Austria.
2012 - Atual Poster Presentation: hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells
Simpósio
 Cell Symposia: Angiogenesis, metabolic regulation and cancer biology, Belgium.
2011 - Atual Poster Presentation: human mesenchymal stromal cells as pro-angiogenic drug release systems
Encontro
 4th International Angiogenesis Meeting, The Netherlands.
Universiteit Twente, Países Baixos
2011 - Atual 20th conference of the Netherlands Society for Biomaterials and Tissue Engineering
Conferência
 20th conference of the Netherlands Society for Biomaterials and Tissue Engineering
2011 - Atual 21st Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
Encontro
 21st Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
2011 - Atual High-Throughput screening – shaping a new research area
Oficina (workshop)
 High-Throughput screening – shaping a new research area
2009 - Atual Gordon Research Conference in Vascular Cell Biology
Conferência
 Gordon Research Conference in Vascular Cell Biology
2008 - Atual Poster Presentation: Investigating the role of collagen in osteogenic differentiation of human mesenchymal stem cells
Encontro
 TERMIS EU Meeting, Portugal.
Universiteit Twente, Países Baixos
2008 - Atual Poster Presentation: Investigating the role of the extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells
Oficina (workshop)
 International bone and mineral research society workshop, Switzerland.
Universiteit Twente, Países Baixos
2008 - Atual Poster Presentation: Investigating the role of extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells
Conferência
 17th conference of the Netherlands Society for Biomaterials and Tissue Engineering, The Netherlands.
Universiteit Twente, Países Baixos
2007 - Atual Dutch Program for Tissue Engineering meeting
Encontro
 Dutch Program for Tissue Engineering meeting
2007 - Atual 1st Dutch Conference on Bio-Medical Engineering
Conferência
 1st Dutch Conference on Bio-Medical Engineering
2005 - Atual 15th Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
Encontro
 15th Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
2005 - Atual iBME Meeting
Encontro
 iBME Meeting
2005 - Atual Dutch Symposium on Tissue Engineering
Simpósio
 Dutch Symposium on Tissue Engineering
2005 - Atual Embryonic Stem Cells symposium, Hubrecht Laboratory, April 2005, The Netherlands.
Simpósio
 Embryonic Stem Cells symposium
Hubrecht Institute, Países Baixos
2005 - Atual International Workshop textbook Tissue Engineering
Oficina (workshop)
 International Workshop textbook Tissue Engineering
2004 - Atual 13th conference of the Netherlands Society for Biomaterials and Tissue Engineering
Conferência
 13th conference of the Netherlands Society for Biomaterials and Tissue Engineering
2000 - Atual 2nd Meeting of Applied Biology
Encontro
 2nd Meeting of Applied Biology, University of Minho
Universidade do Minho, Portugal
1999 - Atual 1st Meeting of Applied Biology
Encontro
 1st Meeting of Applied Biology
Universidade do Minho, Portugal
2024/09/27 - 2024/09/27 European researcher´s night
Exposição
Universidade de Coimbra, Portugal
2024/06/24 - 2024/06/28 “Ocupação científica de jovens nas férias” - week-long activity where we hosted two high-school students in our lab and expose them to what is like to do research on stem cell biology.
Outro
 Ocupação científica de jovens nas férias
Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2024/06/05 - 2024/06/05 Tardes Comunitarias activities are aimed at the population aged >55 and and intends to provide access to activities organized by different services, namely social action, culture, sports, civil protection, and tourism. The goal is to foster social and civic participation, the exchange of experiences, and provide diverse activities that allow the sharing of ideas, knowledge, and moments of social interaction, while stimulating a continuous desire for knowledge. The activity usually have 40-60 participants.
Oficina (workshop)
 Tardes Comunitárias - A CIÊNCIA POR DETRÁS DA LONGEVIDADE
Câmara Municipal Cantanhede, Portugal
2024/06/05 - 2024/06/05 Neurocurios@s is a science communication project that is part of the DYNA Brain project. This project combines curiosity with illustration and neuroscience. Primary school students (second cycle) and neuroscientists will work together to promote neuroscience literacy and stimulate society's curiosity about the brain. Within this project, my lab organised activities related with stem cells (seminar, hands-on experiments including preparation of samples for histology)
Outro
 Neurocurios@s
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/12/06 - 2023/12/07 Participation in the 3rd RESETAgeing Conference
Conferência
 3rd RESETAgeing Conference
2023/06/10 - 2023/06/13 37th Annual Meeting of the International Society for Heart Research - European Section Session Chair and Poster Evaluator
Conferência
 37th Annual Meeting of the International Society for Heart Research - European Section
International Society for Heart Research, Estados Unidos
2022/03/10 - 2022/03/11 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Chair of the panel on Exosomes.
Encontro
 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
2021/10/15 - 2021/10/15 Stem Cell Day 2021 - event organized by the Portuguese Society Stem Cells and Cell Therapy in collaboration with Ciência Viva
Seminário
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal

Ciência Viva, Portugal
2019/12/19 - 2019/12/20 CIBB Meeting 2019 - meeting organised by CIBB to foster collaboration between its members. Chair of the session on Advanced Therapies
Encontro
CNC.IBILI, Portugal
2019/11 - 2019/11 Semana Ciência e da Tecnologia 2019 - lab tour to high-school students at UC-Biotech. Science and Technology week 2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/12/18 Looking at the Heart from the Outside: Novel Mechanisms and Therapeutic Avenues
Arguente principal
 Elsa Daniela Silva (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/11/27 Using a 3D cardiac model derived from HPSC to study heart developmental toxicity
Arguente principal
 Carolina Rosado Correia (Mestrado)
Universidade Nova de Lisboa, Portugal
2024/10/11 Age-Tailored Biological and Biomaterial Approaches for Wound Healing.
Arguente principal
 Eva Batista (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024/07/18 UNRAVELING NEUROVASCULAR DYSFUNCTION IN MACHADO-JOSEPH DISEASE: MESENCHYMAL STROMAL CELLS AS A PROMISING THERAPY
Presidente do júri
 Maria Inês Veiga de Almeida Barros (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2024/05/15 Refining direct cardiac reprogramming: modulation of mitochondrial metabolism and long non-coding RNAs
Arguente principal
 Francisco José Furtado dos Santos (Doutoramento)
Universidade de Aveiro, Portugal
2024/01/30 STAPHYLOCOCCUS AUREUS INTRACELLULAR LIFESTYLE: PHENOTYPIC PROFILES AND UNDERLYING MOLECULAR DETERMINANTS
Presidente do júri
 Inês Rodrigues Lopes (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2024/01/22 CHARACTERIZATION OF PROTEIN- PROTEIN INTERACTIONS INVOLVING G PROTEIN-COUPLED RECEPTOR 143 BY COMPUTATIONAL AND PHARMACOLOGICAL METHODS
Presidente do júri
 Beatriz Theresa Ruth Büschbell (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2023/11/21 Single-cell Microcapsules for Biomedical Applications
Arguente principal
 Manuel Pires dos Santos (Mestrado)
Universidade de Aveiro, Portugal
2022/11/28 Using 3D Cardiac Models derived from hPSCs for Cardiac Toxicity Studies during Heart Development
Arguente principal
 Tiago Alexandre Correia Nunes (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/10/13 Leveraging machine Learning to design CPP for therapeutic cargo delivery
Arguente principal
 Francisco João Manteigas Duarte (Mestrado)
Universidade de Coimbra, Portugal
2022/07/13 Bioactive nanovesicles from umbilical cord blood to treat diabetic chronic wounds
Arguente
 Helena Antunes (Doutoramento)
Universidade de Coimbra, Portugal
2021/12/07 Tailoring of the cellular microenvironment to guide cell fate and functions for bone tissue engineering strategies
Arguente principal
 Diana Sofia Santiago Jesus (Mestrado)
Universidade de Aveiro, Portugal
2021/11/29 mirnas in pericardial fluid and their role in cardiac fibrosis - conversations inside us and how they change our hearts
Arguente principal
 Francisco Ribeiro Coelho de Melo Costa (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2021/04/06 Contribution of Aging and Senescence to Intervertebral Disc Degeneration
Arguente principal
 Emanuel Novais (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
2021/03 Bioencapsulamento de células estaminais e endoteliais para criação de um novo modelo in vitro de ossificação endocondral
Arguente principal
 Inês de Jesus Fernandes (Mestrado)
Universidade de Aveiro, Portugal
2021/01/20 Healthy ageing: the heart of the matter is outside of the heart.
Arguente principal
 Federica de Majo (Doutoramento)
Universiteit Maastricht, Países Baixos
2020/12/17 Investigating the therapeutic potential of extracellular vesicles from hiPSCs and hiPSC-derived cardiac cells for heart regeneration
Arguente principal
 Marta Rodrigues Oliveira (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 3D hybrid scaffolds for Tissue Engineering
Arguente principal
 Sara Neves (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2018 Towards the development of potency assays and 3D inflammation models to evaluate the regenerative potential of mesenchymal/stromal cell (MSC) and MSC-derived products
Arguente principal
 Raquel Cunha (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Vascular organ-on-a-chip platforms for disease modeling
Arguente
 João Ribas (Doutoramento)
Universidade de Coimbra, Portugal
2017 Development of a new nanostructure scaffold for neural stem/progenitor cell transplantation
Arguente principal
 Tânia Vieira (Doutoramento)
Universidade Nova de Lisboa, Portugal
2017 Microengineered 3D in vitro model of human pulmonary alveoli: curvatures influence on lung epithelial cells
Arguente principal
 Sara Vilabril (Mestrado)
Universidade de Coimbra, Portugal

Universiteit Twente, Países Baixos
2016 Bioengineering platforms to modulate the activity of smooth muscle cells derived from progeria-induced pluripotent stem cells
Arguente
 Patrícia Pitrez (Doutoramento)
Universidade do Minho, Portugal
2016 microRNA inhibitor screening: searching for angiogenesis modulators in human endothelial cells
Arguente principal
 Ricardo Abreu (Mestrado)
Universidade de Coimbra, Portugal

Universiteit Maastricht, Países Baixos
2015 Tissue-Engineering approaches to stress urinary incontinence using acellular urethra bioscaffolds
Arguente principal
 Irina Simões (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Engineering the microenvironment of human umbilical cord blood hematopoietic stem/progenitor cells towards efficient megakaryocytic lineage differentiation and platelet production ex-vivo
Arguente principal
 Javad Hatami (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Modulation of induced pluripotency by substrate rigidity
Arguente principal
 Heloísa Salguinho (Mestrado)
Universidade de Coimbra, Portugal
2014 A soft lithography method for patterning calcium phosphate ceramics
Arguente principal
 Daniel Pereira (Mestrado)
Universidade de Coimbra, Portugal

Universiteit Twente, Países Baixos

Arbitragem científica em conferência

Nome da conferência Local da conferência
2024/12/20 - 2024/12/20 CIBB Innovative Therapies Annual Meeting CIBB

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020 - 2023 Pharmaceutics MDPI
2019 - 2023 Biomaterials Science ROYAL SOC CHEMISTRY
2022 - 2022 Materials MDPI
2022 - 2022 Nanoscale Horizons Royal Soc Chemistry
2022 - 2022 Advanced Science Wiley
2022 - 2022 Plos One PUBLIC LIBRARY SCIENCE
2021 - 2021 Advanced Healthcare Materials Wiley
2019 - 2021 Cells MDPI
2020 - 2020 Theranostics IVYSPRING INT PUBL
2020 - 2020 International Journal of Molecular Sciences MDPI
2020 - 2020 Advanced Therapeutics Wiley
2019 - 2019 Journal of Clinical Medicine MDPI
2018 - 2018 Frontiers in Bioengineering and Biotechnology Frontiers Media SA
2016 - 2017 Biomaterials ELSEVIER SCI LTD
2016 - 2016 BMC MUSCULOSKELETAL DISORDERS BMC
2015 - 2015 BMC Biotechnology BMC
2011 - 2014 ECM Journal AO RESEARCH INSTITUTE DAVOS-ARI

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2020 - Atual Expert for the evaluation of Research Project Action Medical Research
2020 - Atual Expert for the evaluation of Research Project Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2019 - Atual Expert for the evaluation of Research Project The Dunhill Medical Trust
2018 - Atual Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Avaliador
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2016 - Atual Expert for the evaluation of Grants
Avaliador
 Agence nationale de la recherche, França Agence nationale de la recherche
2016 - Atual Expert for the evaluation of Grant applications
Avaliador
 The National Science Centre
2020/09 - 2020/11 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Avaliador
 European Commission, Bélgica
2019/10 - 2019/11 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Avaliador
 European Commission
2017 - 2017 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Avaliador
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022/03 - Atual Lecture to the student enrolled in the PhD program Cardiovascular Sciences. Title: cardiovascular regenerative Medicine Universidade de Coimbra, Portugal
2021/11 - Atual Extracellular Vesicles and Regenerative Medicine (Mestrado integrado) Universidade de Coimbra, Portugal
2021/04/07 - Atual Lecture "Cardiovascular Regenerative Medicine" (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/10/02 - Atual Lecturer Master Biomedical Engineering - Regenerative Medicine. Two (3h) classes on Adult Stem Cells and High-Throughput Screening. (Mestrado) Universidade de Coimbra, Portugal
2019 - Atual Human cardiac stem cell therapy PhD Program in Health Sciences - Faculty of Medicine, University Coimbra, Portugal Universidade de Coimbra, Portugal
2018 - Atual Lecturer Master Biomedical Engineering - Regenerative Medicine. Two (3h) classes on Adult Stem Cells and High-Throughput Screening. Master Biomedical Engineering (Mestrado) Universidade de Coimbra, Portugal
2013 - Atual Organization/Responsible/Lecturer course Advanced Cell Biology (Bacharelato) Universiteit Twente, Países Baixos
2013 - Atual Organization/Responsible/Lecturer course Advanced Cell Biology (Mestrado) Universiteit Twente, Países Baixos
2023/10/27 - 2023/10/27 Unlocking the regenerative potential of extracellular vesicles: bioactivity enhancement through miRNA modulation Master Biomedical Research (Mestrado integrado)
2022/10 - 2022/11 Regenerative Medicine - Master Biomedical Engineering
2021/10 - 2021/12 Regenerative Medicine - Master Biomedical Engineering Master Biomedical Engineering (Mestrado integrado) Universidade de Coimbra, Portugal
2019/12/09 - 2019/12/09 Lecture "Biomaterials and stem cell-based therapies" Master Chemical Engineerting (Mestrado integrado) Universidade de Coimbra, Portugal
2019/01 - 2019/04 Organisation of the course on Biotechnology (Outros) Instituto de Educação e Cidadania, Portugal
2015 - 2018 Lecturer Doctoral Programme in Ageing and Chronic Diseases (Doutoramento) Universidade de Coimbra, Portugal
2014 - 2017 Lecturer at the Doctoral Program Experimental Biology and Medicine (Doutoramento) Universidade de Coimbra, Portugal
2005 - 2013 Lecturer for Master course in Advanced Cell Biology (Mestrado) Universiteit Twente, Países Baixos
2005 - 2013 Lecturer Bachelor Course Advanced Cell Biology (Bacharelato) Universiteit Twente, Países Baixos

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2018 Ligação entre médicos e investigadores Jornal Associação Portuguesa Intervenção Cardiovascular
2011 Love in the lab - tissue engineers form creative alliance; UTNieuws
2007 Além fronteiras e ciência em Portugês - entrevista a cientistas Portugueses Revista Mundus

Membro de associação

Nome da associação Tipo de participação
2020/02 - Atual Portuguese Society of Diabetology
2019/10 - Atual Portuguese Society of Stem Cells and Cell Therapy Board member (Secretary)
2009 - Atual Member of the Portuguese Society of Stem Cells and Cellular Therapy National Coordinator of the section "Science and technology of Stem Cells"
2017/10 - 2019/10 Portuguese Society of Stem Cells and Cell Therapy Member and National Coordinator of the working group "Science and Technology of Stem cells"

Tutoria

Tópico Nome do aluno
2024/06 - 2024/07 Liverpool Jonh Moores University visiting students Joe Flaherty, Aidan Thornley, Nikhil Babudas and Laura Mitchell
2017/06 - 2017/08 Supervision of short-term lab rotations for students enrolled in PhD programs Mariana Branco
Distinções

Prémio

2023 Best oral communication, Sociedade Portuguesa Diabetologia
Sociedade Portuguesa de Diabetologia, Portugal
2020 FCT Scientific Employment Stimulus Award
Fundação para a Ciência e a Tecnologia, Portugal
2019 Best poster award, EMBO advanced course in extracellular vesicles, Heidelberg, Germany, April 2018
European Molecular Biology Laboratory, Alemanha
2019 Best Oral Communication, 3rd National Congress of Biomedical Laboratory Sciences
2012 Travel Award - TERMIS World Congress
Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2011 Best Paper (2010-2011) from the Dutch Bone and Mineral Society
Dutch Bone and Mineral Society, Países Baixos
2010 Science Factor - Best Scientific Idea
Universiteit Twente, Países Baixos