Alexandra P Marques (D010-9646-F5CA)

Curriculum Vitae

Alexandra P Marques

Alexandra P. Marques holds an Habilitation in Tissue Engineering, Regenerative Medicine and Stem Cells with a specialization in Stem cells (2020), a PhD on Materials Science and Technology - Biomaterials (2004) and a BSc in Biochemistry (1997). She is a Founder and Coordinating Investigator (Equivalent to Full Professor) of the 3Bs Research Group, University of Minho, Portugal, a research unit of the I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics of which she was also vice-president (2018-2022). She is also in the Governing Board of the PT Government Associate Laboratory ICVS/3B´s. She has been actively participating in the activities (organising and scientific committees, and International Advisory Board of conferences) of different Societies including TERMIS and the European Wound Management Association (EWMA), in this first as elected member of the council and member of the scientific committee, and since 2020 member of the executive committee and elected honorary secretary. Recently she became chair of the EWMA Working Group on Translational Research that places her among key academic, clinical and industrial partners. She is currently Associate Editor of the Skin Physiology Section, Frontiers in Physiology, and was Associate Editor (2017-2020) and Assistant Editor (2009-2016) of the Journal of Tissue Engineering and Regenerative Medicine. She is also Member of the editorial board and Guest/Topic editor of several journals. Her research interests focus on understanding the role of stem cells and the extracellular matrix in the mechanisms of regeneration and in the in vitro mimicry of these processes. She has been also extending her research to the development of accurate and reliable 3D skin tissue models depicting key pathophysiological markers of chronic, genetic and neoplastic skin diseases for which she was awarded an ERC Consolidator Grant. Her work has been also contributing to unravel key aspects that can be used in the development of improved therapies for chronic wounds such as diabetic foot ulcer (DFUs). Alexandra P. Marques edited 2 books, 1 section of an encyclopaedia, is author of 278 publications (134 peer-reviewed publications, 24 book chapters, 120 Indexed conference abstracts and proceedings), and more than 330 communications in international conferences. In addition, she is co-inventor of 11 families of patents.

Ler resumo completo ↓

Identificação

Identificação pessoal

Nome completo: Alexandra P Marques

Nomes de citação

Marques, Alexandra
Alexandra P. Marques
Marques, Alexandra P.

Identificadores de autor

Ciência ID: D010-9646-F5CA
ORCID iD: 0000-0002-3222-0310
Google Scholar ID: https://scholar.google.pt/citations?hl=pt-PT&user=UErW458AAAAJ
Researcher Id: B-1238-2012
Scopus Author Id: 22035647000

Endereços de correio eletrónico

apmarques@i3bs.uminho.pt (Profissional)

Telefones

Telefone

253510908 (Profissional)

Moradas

I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, 4805-017, Barco GMR, Guimarães, Portugal (Profissional)

Websites

https://3bs.uminho.pt/people/149 (Profissional)

Domínios de atuação

Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Espanhol; Castelhano	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Francês	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2020/06/30 Concluído	Tissue Engineering, Regenerative Medicine and Stem Cells - Specialty Stem Cells (Título de Agregado) Universidade do Minho, Portugal
2000/07/01 - 2004/11/26 Concluído	Materials Sciences and Technology - Biomaterials (Doutoramento) Universidade do Minho Escola de Engenharia, Portugal "Biofunctionality and Immunocompatibility of Starch-Based Biomaterials" (TESE/DISSERTAÇÃO)	Aprovada
1998/09/01 - 1999/07/31 Concluído	Biomedical Engineering (Curso de mestrado (conclusão do curso de especialização)) Universidade do Porto Faculdade de Engenharia, Portugal	15
1993/09/20 - 1997/12/11 Concluído	Biochemistry (Licenciatura) Especialização em Bioquímica Aplicada Universidade do Porto Faculdade de Ciências, Portugal "Avaliação da relevância da excrecção fraccional de fósforo na prevenção de insuficiências renais crónicas em gatos domésticos" (TESE/DISSERTAÇÃO)	14

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2022/07/08 - Atual	Investigador Coordenador (carreira) (Investigação)	Universidade do Minho, Portugal

Projetos

Projeto

	Designação	Financiadores
2017/05/01 - 2023/07/30	ECM-INK - Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models ERC-2016-COG-726061 Investigador responsável Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal	European Research Council Concluído
2021/07/01 - 2023/06/30	H2Cure - Desenvolvimento de formulações de Géis e pensos de Mel, Goma Gelana e Ácido Hialurónico para tratamento de feridas POCI-01-0247-FEDER-047032 PI at University of Minho Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal Universidade do Porto Faculdade de Engenharia, Portugal Portus Pharma, LDA, Portugal	Agência Nacional de Inovação SA Concluído
2019/01/01 - 2022/12/31	Sub project 3- Microalgas na cosmética natural of ALGAVALOR - MicroALGAS: produção integrada de VALORização da biomassa e das suas diversas aplicações POCI-01-0247-FEDER-035234 Investigador responsável Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal Universidade de Aveiro Departamento de Química, Portugal Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal Allmicroalgae, Portugal	Agência Nacional de Inovação SA Concluído
2020/06/01 - 2022/08/31	BioPrint4All - A 3D-bioprinting platform with exchangeable tailor-made print heads to engineer tissue surrogates ERC-2019-PoC-899953 Investigador responsável Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal	European Research Council Concluído
2018/06/01 - 2022/05/31	StemTREAT - Human mensenchymal stem cells-based tissue engineering systems for Epidermolysis Bullosa treatment PTDC/BTM-ORG/28131/2017 Co-PI Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2020/01/01 - 2021/03/20	PATCHED - Microfabricated hydrogel-based complex patch with time dependent controlled multiple-release of biomolecules for improved healing of skin Wounds ERC-2019-PoC-862595 Core team member Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal	European Research Council Concluído
2017/09/01 - 2020/11/30	Dressing4Scars - New 4D printing dressing to treat skin scars M-ERA.NET/0013/ 2016 Investigador responsável Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal Izertis, Espanha Royal College of Surgeons in Ireland, Irlanda	Fundação para a Ciência e a Tecnologia Concluído
2015/03/01 - 2019/07/06	HAIRquivalent - bioengineered hair follicles equivalents with controlled biological and architectural configuration IF/00945/2014 Investigador responsável Universidade do Minho, Portugal I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/06/01 - 2019/05/31	VESCells - Single-step fabrication of biofunctional blood vessel substitutes by using electrospinning technologies and mesenchymal stem cells PTDC/BBB-BMD/5468/2014 Team member Universidade do Minho, Portugal 3B's Research Group, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/04/01 - 2019/03/31	Research Line - Targeting ageing-associated diseases/disorders by exploring stem cells biology and biochemistry NORTE-01-0145-FEDER-000021 Investigador responsável Universidade do Minho, Portugal 3B's Research Group, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluído
2015/12/01 - 2018/11/30	GENE2SKIN - Roadmap for advanced genetic engineering-based skin therapies, H2020-TWINN-2015 H2020-TWINN-2015 Co-PI Universidade do Minho, Portugal 3B's Research Group, Portugal Royal College of Surgeons in Ireland, Irlanda King's College London, Reino Unido	European Commission Concluído
2013/06/01 - 2018/05/31	ComplexiTE - An integrated multidisciplinary tissue engineering approach combining novel high-throughput screening and advanced methodologies to create complex biomaterials-stem cells constructs ERC-2012-AdG-321266 Core team member Universidade do Minho, Portugal 3B's Research Group, Portugal	European Research Council Concluído
2014/01/01 - 2015/08/31	BIOTERFACE - Design of Biocompatible and Customized interfaces, surface and coatings for Intra Ocular Lens M-ERA.NET/0003/2012 PI at University of Minho Universidade do Minho, Portugal 3B's Research Group, Portugal Institituto Oftalmológico Fernández – Vega, S.L., Espanha AJL OPHTHALMIC, S.A, Espanha	Fundação para a Ciência e a Tecnologia Concluído
2010/04/01 - 2013/03/31	Skingineering - Engineering skin analogues through cell sheet technology PTDC/SAU-OSM/099422/2008 Investigador responsável Universidade do Minho, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal 3B's Research Group, Portugal AJL OPHTHALMIC, S.A, Espanha	Fundação para a Ciência e a Tecnologia Concluído
2010/04/01 - 2013/03/31	OsteoGraphy - 3D patterned co-culture system to develop vascularized engineered bone FCT-PTDC/EME-MFE/108892/2008 Team member Universidade do Minho, Portugal 3B's Research Group, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2008/01/01 - 2009/10/31	Metal/porcelain interfaces for restorative dentistry: A new approach including improvement of tribo-corrosion properties, modelling and simulation of physicochemical and mechanical behaviour and biocompatibility studies FCT-PTDC/CTM/67500/2006 Team member Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2008/01/01 - 2009/10/31	Surface modification vs. tribocorrosion mechanisms and cytotoxicity in Ti and Ti alloys for dental applications FCT-PTDC/CTM/68160/2006 Team member Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2004/10/01 - 2009/09/30	EXPERTISSUES Network of Excellence - Novel Therapeutic Strategies for Tissue Engineering of Bone and Cartilage Using Second Generation Biomimetic Scaffolds FP6-NMP3-CT-2004-500283 Bolseiro de Cientista Convidado Universidade do Minho, Portugal 3B's Research Group, Portugal	European Commission Sixth Framework Programme Concluído
2004/01/01 - 2008/06/30	HIPPOCRATES - A Hybrid Approach and Cartilage Tissue Engineering using Natural Origin Scaffolds, Progenitor Cells and Growth Factors FP6 - NMP3-CT-2003-505758 Investigador Universidade do Minho, Portugal	European Commission Sixth Framework Programme Concluído

Produções

Publicações

Artigo em conferência	Pereira, D. R.; Canadas, R. F.; Silva-Correia, J.; Marques, Alexandra P. ; Reis, R. L.; Oliveira, J. M.; Pereira, D.R.; et al. "Gellan gum-based Hydrogel Bilayered Scaffolds for Osteochondral Tissue Engineering". Trabalho apresentado em 25th Symposium and Annual Meeting of the International Society for Ceramics in Medicine (Bioceramics 25), Bucarest, 2014. 10.4028/www.scientific.net/KEM.587.255 Ribeiro, V. P.; Ribeiro, A. S.; Silva, C. J.; Durães, N. F.; Bonifácio, G.; Correlo, V. M.; Marques, Alexandra P. ; et al. "Evaluation of Novel 3D Architectures Based on Knitting Technologies for Engineering Biological Tissues". Trabalho apresentado em International Conference on Medical Textiles and Healthcare Products (MedTex13), Raleigh, 2013.
Artigo em revista	de Andrade, Ana L. Martins; da Silva, Lucilia P.; Parizotto, Nivaldo A.; Brassolatti, Patrícia; Liebano, Richard E.; Marques, Alexandra P.. "Effect of photobiomodulation on the behaviour of mesenchymal stem cells in three-dimensional cultures". Lasers in Medical Science 38 1 (2023): 221. http://dx.doi.org/10.1007/s10103-023-03883-2. Publicado • 10.1007/s10103-023-03883-2 Malta, Mariana D. ; Cerqueira, Mariana T.; Marques, Alexandra P.. "Extracellular matrix in skin diseases: The road to new therapies". Journal of Advanced Research 51 (2023): 149-160. http://dx.doi.org/10.1016/j.jare.2022.11.008. Acesso aberto • Publicado • 10.1016/j.jare.2022.11.008 Abreu, Carla M.; Lago, Manuela E.L.; Pires, Joana; Reis, Rui L.; da Silva, Lucília P.; Marques, Alexandra P.. "Gellan gum-based hydrogels support the recreation of the dermal papilla microenvironment". Biomaterials Advances 150 (2023): 213437. http://dx.doi.org/10.1016/j.bioadv.2023.213437. Publicado • 10.1016/j.bioadv.2023.213437 Piaggesi, Alberto; Bassetto, Franco; den Braber, Edwin; Dallla, Luca P.; Marques, Alexandra. P.; Raspovic, Katherine; Téot, Luc; Triulzi, Isotta; Turchetti, Giuseppe. "New technologies for tissue replacement". Journal of Wound Management 24 1 (2023): Suppl 1. http://dx.doi.org/10.35279/jowm2023.24.01.sup01. Publicado • 10.35279/jowm2023.24.01.sup01 Mendes, Ana I.; Fraga, Alexandra G.; Peixoto, Maria J.; Aroso, Ivo; Longatto-Filho, Adhemar; Marques, Alexandra P.; Pedrosa, Jorge. "Gellan gum spongy-like hydrogel-based dual antibiotic therapy for infected diabetic wounds". Bioengineering & Translational Medicine 8 3 (2023): http://dx.doi.org/10.1002/btm2.10504. 10.1002/btm2.10504 Helena R. Moreira; Cerqueira, Mariana T.; da Silva, Lucilia P.; Pires, Joana; Jarnalo, Mariana; Horta, Ricardo; Reis, Rui L.; Marques, Alexandra P.. "Pre-selection of fibroblast subsets prompts prevascularization of tissue engineered skin analogues". Biomaterials Science (2023): https://doi.org/10.1039/D2BM02022J. 10.1039/D2BM02022J Moreira, Helena R.; Rodrigues, Daniel B.; Freitas-Ribeiro, Sara; da Silva, Lucília P.; Morais, Alain da S.; Jarnalo, Mariana; Horta, Ricardo; et al. "Spongy-like hydrogels prevascularization with the adipose tissue vascular fraction delays cutaneous wound healing by sustaining inflammatory cell influx". Materials Today Bio 17 (2022): 100496. http://dx.doi.org/10.1016/j.mtbio.2022.100496. Acesso aberto • Publicado • 10.1016/j.mtbio.2022.100496 Rodrigues, Daniel B.; Moreira, Helena R.; Cerqueira, Mariana T.; Marques, Alexandra P.; Castro, António G.; Reis, Rui L.; Pirraco, Rogério P.. "Highly tailorable gellan gum nanoparticles as a platform for the development of T cell activator systems". Biomaterials Research 26 1 (2022): 48. http://dx.doi.org/10.1186/s40824-022-00297-z. Acesso aberto • Publicado • 10.1186/s40824-022-00297-z Moreira, Helena R.; Rodrigues, Daniel B.; Freitas-Ribeiro, Sara; da Silva, Lucília P.; da S. Morais, Alain; Jarnalo, Mariana; Horta, Ricardo; et al. "Integrin-specific hydrogels for growth factor-free vasculogenesis". npj Regenerative Medicine 7 1 (2022): 57. http://dx.doi.org/10.1038/s41536-022-00253-4. Acesso aberto • Publicado • 10.1038/s41536-022-00253-4 Mendes, Ana I.; Peixoto, Maria J.; Marques, Alexandra P.; Pedrosa, Jorge; Fraga, Alexandra G.. "An optimized mouse model of Staphylococcus aureus infected diabetic ulcers". BMC Research Notes 15 1 (2022): 293. http://dx.doi.org/10.1186/s13104-022-06170-5. Publicado • 10.1186/s13104-022-06170-5 Fernandes, Maria G.; da Silva, Lucília P.; Cerqueira, Mariana T.; Ibañez, Rita; Murphy, Ciara M.; Reis, Rui L.; O´Brien, Fergal J.; Marques, Alexandra P.. "Mechanomodulatory biomaterials prospects in scar prevention and treatment". Acta Biomaterialia 150 (2022): 22-33. http://dx.doi.org/10.1016/j.actbio.2022.07.042. Publicado • 10.1016/j.actbio.2022.07.042 Guimarães, Carlos F.; Marques, Alexandra P.; Reis, Rui L.. "Pushing the Natural Frontier: Progress on the Integration of Biomaterial Cues toward Combinatorial Biofabrication and Tissue Engineering". Advanced Materials 34 33 (2022): 2105645. http://dx.doi.org/10.1002/adma.202105645. Publicado • 10.1002/adma.202105645 Mendes, Ana I.; Rebelo, Rita; Aroso, Ivo; Correlo, Vitor M.; Fraga, Alexandra G.; Pedrosa, Jorge; Marques, Alexandra P.. "Development of an antibiotics delivery system for topical treatment of the neglected tropical disease Buruli ulcer". International Journal of Pharmaceutics 623 (2022): 121954. http://dx.doi.org/10.1016/j.ijpharm.2022.121954. Acesso aberto • Publicado • 10.1016/j.ijpharm.2022.121954 Bártolo, Inês; Reis, Rui L.; Marques, Alexandra P.; Cerqueira, Mariana T.. "Keratinocyte Growth Factor-Based Strategies for Wound Re-Epithelialization". Tissue Engineering Part B: Reviews 28 3 (2022): 665-676. http://dx.doi.org/10.1089/ten.teb.2021.0030. Publicado Canadas, Raphaël F; Liu, Ziyu; Gasperini, Luca; Fernandes, Diogo C; Maia, Fátima R; Reis, Rui L; Alexandra P. Marques; Liu, Chaozong; Oliveira, Joaquim M. "Numerical and experimental simulation of a dynamic-rotational 3D cell culture for stratified living tissue models". Biofabrication 14 2 (2022): 025022. http://dx.doi.org/10.1088/1758-5090/ac55a2. Publicado • 10.1088/1758-5090/ac55a2 Reis, Daniel P.; Domingues, Beatriz; Fidalgo, Cátia; Reis, Rui L.; Gasperini, Luca; Marques, Alexandra P.. "Bioinks Enriched with ECM Components Obtained by Supercritical Extraction". Biomolecules 12 3 (2022): 394. http://dx.doi.org/10.3390/biom12030394. Acesso aberto • Publicado • 10.3390/biom12030394 Moreira, Helena R.; Marques, Alexandra P.. "Vascularization in skin wound healing: where do we stand and where do we go?". Current Opinion in Biotechnology 73 (2022): 253-262. http://dx.doi.org/10.1016/j.copbio.2021.08.019. 10.1016/j.copbio.2021.08.019 Ibanez, Rita I. R.; do Amaral, Ronaldo J. F. C.; Simpson, Christopher R.; Casey, Sarah M.; Reis, Rui L.; Marques, Alexandra P.; Murphy, Ciara M.; O'Brien, Fergal J.. "3D Printed Scaffolds Incorporated with Platelet-Rich Plasma Show Enhanced Angiogenic Potential while not Inducing Fibrosis". Advanced Functional Materials 32 10 (2021): 2109915. http://dx.doi.org/10.1002/adfm.202109915. 10.1002/adfm.202109915 Guimarães, Carlos F.; Ahmed, Rajib; Mataji-Kojouri, Amideddin; Soto, Fernando; Wang, Jie; Liu, Shiqin; Stoyanova, Tanya; et al. "Engineering Polysaccharide-Based Hydrogel Photonic Constructs: From Multiscale Detection to the Biofabrication of Living Optical Fibers". Advanced Materials 33 52 (2021): 2105361. http://dx.doi.org/10.1002/adma.202105361. 10.1002/adma.202105361 Canadas, Raphaël F.; Costa, João B.; Mao, Zhengwei; Gao, Changyou; Demirci, Utkan; Reis, Rui L.; Marques, Alexandra P.; Oliveira, Joaquim M.. "3DICE coding matrix multidirectional macro-architecture modulates cell organization, shape, and co-cultures endothelization network". Biomaterials 277 (2021): 121112. http://dx.doi.org/10.1016/j.biomaterials.2021.121112. 10.1016/j.biomaterials.2021.121112 R. Ibañez, Rita I.; do Amaral, Ronaldo J. F. C.; Reis, Rui L.; Marques, Alexandra P.; Murphy, Ciara M.; O’Brien, Fergal J.. "3D-Printed Gelatin Methacrylate Scaffolds with Controlled Architecture and Stiffness Modulate the Fibroblast Phenotype towards Dermal Regeneration". Polymers 13 15 (2021): 2510. http://dx.doi.org/10.3390/polym13152510. 10.3390/polym13152510 Abreu, Carla M.; Marques, Alexandra P.. "Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls". Bioengineering & Translational Medicine 7 1 (2021): http://dx.doi.org/10.1002/btm2.10235. 10.1002/btm2.10235 Abreu, Carla M.; Reis, Rui L.; Marques, Alexandra P.. "Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions". Cell Proliferation 54 7 (2021): http://dx.doi.org/10.1111/cpr.13013. 10.1111/cpr.13013 Guimarães, Carlos F.; Gasperini, Luca; Marques, Alexandra P.; Reis, Rui L.. "3D flow-focusing microfluidic biofabrication: One-chip-fits-all hydrogel fiber architectures". Applied Materials Today 23 (2021): 101013. http://dx.doi.org/10.1016/j.apmt.2021.101013. 10.1016/j.apmt.2021.101013 Abreu, Carla M.; Cerqueira, Mariana T.; Pirraco, Rogério P.; Gasperini, Luca; Reis, Rui L.; Marques, Alexandra P.. "Rescuing key native traits in cultured dermal papilla cells for human hair regeneration". Journal of Advanced Research 30 (2021): 103-112. http://dx.doi.org/10.1016/j.jare.2020.10.006. 10.1016/j.jare.2020.10.006 Guimarães, Carlos F.; Ahmed, Rajib; Marques, Alexandra P.; Reis, Rui L.; Demirci, Utkan. "Engineering Hydrogel-Based Biomedical Photonics: Design, Fabrication, and Applications". Advanced Materials 33 23 (2021): 2006582. http://dx.doi.org/10.1002/adma.202006582. 10.1002/adma.202006582 Abreu, Carla M.; Pirraco, Rogério P.; Reis, Rui L.; Cerqueira, Mariana T.; Marques, Alexandra P.. Autor correspondente: Marques, Alexandra P.. "Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment". Stem Cell Research & Therapy 12 1 (2021): http://dx.doi.org/10.1186/s13287-020-02104-9. 10.1186/s13287-020-02104-9 Moreira, Helena R.; Raftery, Rosanne M.; da Silva, Lucília P.; Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P.; O'Brien, Fergal J.. "In vitro vascularization of tissue engineered constructs by non-viral delivery of pro-angiogenic genes". Biomaterials Science 9 6 (2021): 2067-2081. http://dx.doi.org/10.1039/d0bm01560a. 10.1039/d0bm01560a Abreu, Carla M.; Gasperini, Luca; Lago, Manuela E. L.; Reis, Rui L.; Marques, Alexandra P.. "Microscopy-guided laser ablation for the creation of complex skin models with folliculoid appendages". Bioengineering & Translational Medicine 6 2 (2020): http://dx.doi.org/10.1002/btm2.10195. 10.1002/btm2.10195 Canadas, Raphaël F.; Patrício, Pedro; Brancato, Virginia; Gasperini, Luca; Caballero, David; Pires, Ricardo A.; Costa, João B.; et al. "Convection patterns gradients of non-living and living micro-entities in hydrogels". Applied Materials Today 21 (2020): 100859. http://dx.doi.org/10.1016/j.apmt.2020.100859. 10.1016/j.apmt.2020.100859 Oliveira, Catarina; Soares, Ana I.; Neves, Nuno M.; Reis, Rui L.; Marques, Alexandra P.; Silva, Tiago H.; Martins, Albino. "Fucoidan Immobilized at the Surface of a Fibrous Mesh Presents Toxic Effects over Melanoma Cells, But Not over Noncancer Skin Cells". Biomacromolecules 21 7 (2020): 2745-2754. http://dx.doi.org/10.1021/acs.biomac.0c00482. 10.1021/acs.biomac.0c00482 Guimarães, Carlos F.; Gasperini, Luca; Marques, Alexandra P.; Reis, Rui L.. "The stiffness of living tissues and its implications for tissue engineering". Nature Reviews Materials 5 5 (2020): 351-370. http://dx.doi.org/10.1038/s41578-019-0169-1. 10.1038/s41578-019-0169-1 Moreira, Helena R.; Silva, Lucília P. da; Reis, Rui L.; Marques, Alexandra P.. "Tailoring Gellan Gum Spongy-Like Hydrogels’ Microstructure by Controlling Freezing Parameters". Polymers 12 2 (2020): 329. http://dx.doi.org/10.3390/polym12020329. 10.3390/polym12020329 Guimarães, Carlos F.; Gasperini, Luca; Ribeiro, Raquel S.; Carvalho, Andreia F.; Marques, Alexandra P.; Reis, Rui L.. "High-throughput fabrication of cell-laden 3D biomaterial gradients". Materials Horizons 7 9 (2020): 2414-2421. http://dx.doi.org/10.1039/d0mh00818d. 10.1039/d0mh00818d Freitas-Ribeiro, Sara; Carvalho, Andreia F.; Costa, Marina; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L; Pirraco, Rogério P.. "Strategies for the hypothermic preservation of cell sheets of human adipose stem cells". PLOS ONE 14 10 (2019): e0222597. http://dx.doi.org/10.1371/journal.pone.0222597. 10.1371/journal.pone.0222597 da Silva, Lucília P.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.. "Hydrogel-Based Strategies to Advance Therapies for Chronic Skin Wounds". Annual Review of Biomedical Engineering 21 1 (2019): 145-169. http://dx.doi.org/10.1146/annurev-bioeng-060418-052422. 10.1146/annurev-bioeng-060418-052422 Carvalho, Ana M.; Marques, Alexandra P.; Silva, Tiago H.; Reis, Rui L.. "Evaluation of the Potential of Collagen from Codfish Skin as a Biomaterial for Biomedical Applications". Marine Drugs 16 12 (2018): 495. http://dx.doi.org/10.3390/md16120495. 10.3390/md16120495 Canadas, Raphaël F.; Ren, Tanchen; Marques, Alexandra P.; Oliveira, Joaquim M.; Reis, Rui L.; Demirci, Utkan. "Biochemical Gradients to Generate 3D Heterotypic-Like Tissues with Isotropic and Anisotropic Architectures". Advanced Functional Materials 28 48 (2018): 1804148. http://dx.doi.org/10.1002/adfm.201804148. 10.1002/adfm.201804148 Pereira, Diana R.; Canadas, Raphael F.; Silva-Correia, Joana; da Silva Morais, Alain; Oliveira, Mariana B.; Dias, Isabe R.; Mano, João F.; et al. "Injectable gellan-gum/hydroxyapatite-based bilayered hydrogel composites for osteochondral tissue regeneration". Applied Materials Today 12 (2018): 309-321. http://dx.doi.org/10.1016/j.apmt.2018.06.005. 10.1016/j.apmt.2018.06.005 Diogo, Gabriela S.; López-Senra, Estefania; Pirraco, Rogério P.; Canadas, Raphael F.; Fernandes, Emanuel M.; Serra, Julia; Pérez-Martín, Ricardo I.; et al. "Marine Collagen/Apatite Composite Scaffolds Envisaging Hard Tissue Applications". Marine Drugs 16 8 (2018): 269. http://dx.doi.org/10.3390/md16080269. 10.3390/md16080269 Lago, Manuela E. L.; da Silva, Lucília P.; Henriques, Catarina; Carvalho, Andreia F.; Reis, Rui L.; Marques, Alexandra P.. "Generation of Gellan Gum-Based Adipose-Like Microtissues". Bioengineering 5 3 (2018): 52. http://dx.doi.org/10.3390/bioengineering5030052. 10.3390/bioengineering5030052 Piaggesi, Alberto; Låuchli, Severin; Bassetto, Franco; Biedermann, Thomas; Marques, Alexandra P.; Najafi, Bijan; Palla, Ilaria; et al. "Advanced therapies in wound management: cell and tissue based therapies, physical and bio-physical therapies smart and IT based technologies". Journal of Wound Care 27 Sup6a (2018): S1-S137. http://dx.doi.org/10.12968/jowc.2018.27.sup6a.s1. 10.12968/jowc.2018.27.sup6a.s1 da Silva, Lucília P.; Jha, Amit K.; Correlo, Vitor M.; Marques, Alexandra P.; Reis, Rui L.; Healy, Kevin E.. "Gellan Gum Hydrogels with Enzyme-Sensitive Biodegradation and Endothelial Cell Biorecognition Sites". Advanced Healthcare Materials 7 5 (2018): 1700686. http://dx.doi.org/10.1002/adhm.201700686. 10.1002/adhm.201700686 Srisuk, Pathomthat; Berti, Fernanda V.; da Silva, Lucilia P.; Marques, Alexandra P.; Reis, Rui L.; Correlo, Vitor M.. "Electroactive Gellan Gum/Polyaniline Spongy-Like Hydrogels". Acs Biomaterials Science & Engineering 4 5 (2018): 1779-1787. 10.1021/acsbiomaterials.7b00917 Canadas, Raphaël F.; Ren, Tanchen; Tocchio, Alessandro; Marques, Alexandra P.; Oliveira, Joaquim M.; Reis, Rui L.; Demirci, Utkan. "Tunable anisotropic networks for 3-D oriented neural tissue models.". Biomaterials 181 (2018): 402-414. 10.1016/j.biomaterials.2018.07.055 Manda, Marianthi G.; da Silva, Lucilia P.; Cerqueira, Mariana T.; Pereira, Diana R.; Oliveira, Mariana B.; Mano, João F.; Marques, Alexandra P.; et al. "Gellan gum-hydroxyapatite composite spongy-like hydrogels for bone tissue engineering". Journal of Biomedical Materials Research Part A 106 2 (2017): 479-490. http://dx.doi.org/10.1002/jbm.a.36248. 10.1002/jbm.a.36248 Reys, Lara L.; Silva, Simone S.; Pirraco, Rogério P.; Marques, Alexandra P.; Mano, João F.; Silva, Tiago H.; Reis, Rui L.. "Influence of freezing temperature and deacetylation degree on the performance of freeze-dried chitosan scaffolds towards cartilage tissue engineering". European Polymer Journal 95 (2017): 232-240. http://dx.doi.org/10.1016/j.eurpolymj.2017.08.017. 10.1016/j.eurpolymj.2017.08.017 Berti, Fernanda V.; Srisuk, Pathomthat; da Silva, Lucília P.; Marques, Alexandra P.; Reis, Rui L.; Correlo, Vitor M.. "Synthesis and Characterization of Electroactive Gellan Gum Spongy-Like Hydrogels for Skeletal Muscle Tissue Engineering Applications". Tissue Engineering Part A 23 17-18 (2017): 968-979. http://dx.doi.org/10.1089/ten.tea.2016.0430. 10.1089/ten.tea.2016.0430 da Silva, Lucília P.; Santos, Tírcia C.; Rodrigues, Daniel B.; Pirraco, Rogério P.; Cerqueira, Mariana T.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.. "Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing". Journal of Investigative Dermatology 137 7 (2017): 1541-1551. http://dx.doi.org/10.1016/j.jid.2017.02.976. 10.1016/j.jid.2017.02.976 Carvalho, Andreia F.; Gasperini, Luca; Ribeiro, Raquel S.; Marques, Alexandra P.; Reis, Rui L.. "Control of osmotic pressure to improve cell viability in cell-laden tissue engineering constructs". Journal of Tissue Engineering and Regenerative Medicine 12 2 (2017): http://dx.doi.org/10.1002/term.2432. 10.1002/term.2432 Costa, Marina; Cerqueira, Mariana T.; Santos, Tírcia C.; Sampaio-Marques, Belém; Ludovico, Paula; Marques, Alexandra P.; Pirraco, Rogério P.; Reis, Rui L.. "Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy". Acta Biomaterialia 55 (2017): 131-143. http://dx.doi.org/10.1016/j.actbio.2017.03.034. 10.1016/j.actbio.2017.03.034 Zhu, Xiandi; Sun, Yn; Chen, Di; Li, Jingfeng; Dong, Xia; Wang, Jie; Chen, Huaiwen; et al. "Mastocarcinoma therapy synergistically promoted by lysosome dependent apoptosis specifically evoked by 5-Fu@nanogel system with passive targeting and pH activatable dual function". Journal of Controlled Release 254 (2017): 107-118. http://dx.doi.org/10.1016/j.jconrel.2017.03.038. 10.1016/j.jconrel.2017.03.038 Ribeiro, Viviana P.; Silva-Correia, Joana; Nascimento, Ana I.; da Silva Morais, Alain; Marques, Alexandra P.; Ribeiro, Ana S.; Silva, Carla J.; et al. "Silk-based anisotropical 3D biotextiles for bone regeneration". Biomaterials 123 (2017): 92-106. http://dx.doi.org/10.1016/j.biomaterials.2017.01.027. 10.1016/j.biomaterials.2017.01.027 Correia, Clara R.; Santos, Tírcia C.; Pirraco, Rogério P.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Mano, João F.. "In vivo osteogenic differentiation of stem cells inside compartmentalized capsules loaded with co-cultured endothelial cells". Acta Biomaterialia 53 (2017): 483-494. http://dx.doi.org/10.1016/j.actbio.2017.02.007. 10.1016/j.actbio.2017.02.007 da Silva, Lucília P.; Oliveira, Sílvia; Pirraco, Rogério P.; Santos, Tírcia C.; Reis, Rui L.; Marques, Alexandra P.; Correlo, Vitor M.. "Eumelanin-releasing spongy-like hydrogels for skin re-epithelialization purposes". Biomedical Materials 12 2 (2017): 025010. http://dx.doi.org/10.1088/1748-605x/aa5f79. 10.1088/1748-605x/aa5f79 da Silva, Lucília P.; Pirraco, Rogério P.; Santos, Tírcia C.; Novoa-Carballal, Ramon; Cerqueira, Mariana T.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.. "Neovascularization Induced by the Hyaluronic Acid-Based Spongy-Like Hydrogels Degradation Products". ACS Applied Materials & Interfaces 8 49 (2016): 33464-33474. http://dx.doi.org/10.1021/acsami.6b11684. 10.1021/acsami.6b11684 Ribeiro, Viviana P.; Almeida, Lília R.; Martins, Ana R.; Pashkuleva, Iva; Marques, Alexandra P.; Ribeiro, Ana S.; Silva, Carla J.; et al. "Modulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applications". Journal of Tissue Engineering and Regenerative Medicine 11 10 (2016): 2853-2863. http://dx.doi.org/10.1002/term.2189. 10.1002/term.2189 Cerqueira, Mariana T.; Pirraco, Rogério P.; Marques, Alexandra P.. "Stem Cells in Skin Wound Healing: Are We There Yet?". Advances in Wound Care 5 4 (2016): 164-175. http://dx.doi.org/10.1089/wound.2014.0607. 10.1089/wound.2014.0607 Oliveira, Sara M.; Pirraco, Rogério P.; Marques, Alexandra P.; Santo, Vítor E.; Gomes, Manuela E.; Reis, Rui L.; Mano, João F.. "Platelet lysate-based pro-angiogenic nanocoatings". Acta Biomaterialia 32 (2016): 129-137. http://dx.doi.org/10.1016/j.actbio.2015.12.028. 10.1016/j.actbio.2015.12.028 Correia, Clara R.; Pirraco, Rogério P.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Mano, João F.. "Semipermeable Capsules Wrapping a Multifunctional and Self-regulated Co-culture Microenvironment for Osteogenic Differentiation". Scientific Reports 6 (2016): 21883. http://dx.doi.org/10.1038/srep21883. 10.1038/srep21883 Santos, Tircia C.; Reis, Rui L.; Marques, Alexandra P.. "Can host reaction animal models be used to predict and modulate skin regeneration?". Journal of Tissue Engineering and Regenerative Medicine 11 8 (2016): 2295-2303. http://dx.doi.org/10.1002/term.2128. 10.1002/term.2128 Mihaila, Silvia M.; Resende, Margarida F.; Reis, Rui L.; Gomes, Manuela E.; Marques, Alexandra P.. "Interactive endothelial phenotype maintenance and osteogenic differentiation of adipose tissue stromal vascular fraction SSEA-4+-derived cells". Journal of Tissue Engineering and Regenerative Medicine 11 7 (2015): 1998-2013. http://dx.doi.org/10.1002/term.2096. 10.1002/term.2096 Cerqueira, Mariana T.; da Silva, Lucilia P.; Correlo, Vitor M.; Reis, Rui L.; Marques, Alexandra P.. "Epidermis recreation in spongy-like hydrogels". Materials Today 18 8 (2015): 468-469. http://dx.doi.org/10.1016/j.mattod.2015.08.018. 10.1016/j.mattod.2015.08.018 Pacheco, Daniela P.; Reis, Rui L.; Correlo, Vítor M.; Marques, Alexandra P.. "The Crosstalk between Tissue Engineering and Pharmaceutical Biotechnology: Recent Advances and Future Directions". Current Pharmaceutical Biotechnology 16 11 (2015): 1012-1023. http://dx.doi.org/10.2174/1389201016666150826120257. 10.2174/1389201016666150826120257 Ribeiro, Viviana P.; Almeida, Lília R.; Martins, Ana R.; Pashkuleva, Iva; Marques, Alexandra P.; Ribeiro, Ana S.; Silva, Carla J.; et al. "Influence of different surface modification treatments on silk biotextiles for tissue engineering applications". Journal of Biomedical Materials Research Part B: Applied Biomaterials 104 3 (2015): 496-507. http://dx.doi.org/10.1002/jbm.b.33400. 10.1002/jbm.b.33400 Zonari, Alessandra; Martins, Thaís M.M.; Paula, Ana Cláudia C.; Boeloni, Jankerle N.; Novikoff, Silviene; Marques, Alexandra P.; Correlo, Vitor M.; Reis, Rui L.; Goes, Alfredo M.. "Polyhydroxybutyrate-co-hydroxyvalerate structures loaded with adipose stem cells promote skin healing with reduced scarring". Acta Biomaterialia 17 (2015): 170-181. http://dx.doi.org/10.1016/j.actbio.2015.01.043. 10.1016/j.actbio.2015.01.043 Custódio, Catarina A.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Mano, João F.. "Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration". Biomaterials 43 (2015): 23-31. http://dx.doi.org/10.1016/j.biomaterials.2014.11.047. 10.1016/j.biomaterials.2014.11.047 Monteiro, Isa P.; Shukla, Anita; Marques, Alexandra P.; Reis, Rui L.; Hammond, Paula T.. "Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering". Journal of Biomedical Materials Research Part A 103 1 (2015): 330-340. http://dx.doi.org/10.1002/jbm.a.35178. 10.1002/jbm.a.35178 Araújo, Ana R.; Pereira, David M.; Aroso, Ivo M.; Santos, Tânia; Batista, Maria T.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.; Pires, Ricardo A.. "Cork extracts reduce UV-mediated DNA fragmentation and cell death". RSC Advances 5 116 (2015): 96151-96157. http://dx.doi.org/10.1039/c5ra15712a. 10.1039/c5ra15712a Pacheco, Daniela P.; Amaral, Maria H.; Reis, Rui L.; Marques, Alexandra P.; Correlo, Vitor M.. "Development of an injectable PHBV microparticles-GG hydrogel hybrid system for regenerative medicine". International Journal of Pharmaceutics 478 1 (2015): 398-408. 10.1016/j.ijpharm.2014.11.036 Baran, Erkan T.; Pirraco, Rogerio P.; Cerqueira, Mariana T.; Marques, Alaxandre P.; Retolaza, Aritz; Merino, Santos; Neves, Nuno M.; Reis, Rui L.. "Depth (Z-axis) control of cell morphologies on micropatterned surfaces". Journal of Bioactive and Compatible Polymers 30 5 (2015): 555-567. 10.1177/0883911515580354 Balmayor, Elizabeth R.; Baran, Turker E.; Unger, Marina; Marques, Alexandra P.; Azevedo, Helena S.; Reis, Rui L.. "Presence of starch enhances in vitro biodegradation and biocompatibility of a gentamicin delivery formulation". Journal of Biomedical Materials Research Part B-Applied Biomaterials 103 8 (2015): 1610-1620. 10.1002/jbm.b.33343 Monteiro, Isa P.; Gabriel, D.; Timko, B.P.; Hashimoto, M.; Karajanagi, S.; Tong, R.; Marques, Alexandra P.; Reis, Rui L.; Kohane, Daniel S.. "A two-component pre-seeded dermal–epidermal scaffold". Acta Biomaterialia 10 12 (2014): 4928-4938. http://dx.doi.org/10.1016/j.actbio.2014.08.029. 10.1016/j.actbio.2014.08.029 Cerqueira, Mariana T.; da Silva, Lucília P.; Santos, Tírcia C.; Pirraco, Rogério P.; Correlo, Vítor M.; Reis, Rui L.; Marques, Alexandra P.. "Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization". ACS Applied Materials & Interfaces 6 22 (2014): 19668-19679. http://dx.doi.org/10.1021/am504520j. 10.1021/am504520j da Silva, Lucília P.; Cerqueira, Mariana T.; Sousa, Rui A.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.. "Engineering cell-adhesive gellan gum spongy-like hydrogels for regenerative medicine purposes". Acta Biomaterialia 10 11 (2014): 4787-4797. http://dx.doi.org/10.1016/j.actbio.2014.07.009. 10.1016/j.actbio.2014.07.009 Mihaila, Silvia M.; Gaharwar, Akhilesh K.; Reis, Rui L.; Khademhosseini, Ali; Marques, Alexandra P.; Gomes, Manuela E.. "The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets". Biomaterials 35 33 (2014): 9087-9099. http://dx.doi.org/10.1016/j.biomaterials.2014.07.052. 10.1016/j.biomaterials.2014.07.052 Gantar, Ana; da Silva, Lucilia P.; Oliveira, Joaquim M.; Marques, Alexandra P.; Correlo, Vitor M.; Novak, Saša; Reis, Rui L.. "Nanoparticulate bioactive-glass-reinforced gellan-gum hydrogels for bone-tissue engineering". Materials Science and Engineering: C 43 (2014): 27-36. http://dx.doi.org/10.1016/j.msec.2014.06.045. 10.1016/j.msec.2014.06.045 Mihaila, Silvia M.; Popa, Elena G.; Reis, Rui L.; Marques, Alexandra P.; Gomes, Manuela E.. "Fabrication of Endothelial Cell-Laden Carrageenan Microfibers for Microvascularized Bone Tissue Engineering Applications". Biomacromolecules 15 8 (2014): 2849-2860. http://dx.doi.org/10.1021/bm500036a. 10.1021/bm500036a Cerqueira, Mariana T.; Pirraco, Rogério P.; Martins, AR.; Santos, Tircia C.; Reis, Rui L.; Marques, Alexandra P.. "Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds". Acta Biomaterialia 10 7 (2014): 3145-3155. http://dx.doi.org/10.1016/j.actbio.2014.03.006. 10.1016/j.actbio.2014.03.006 Cerqueira, Mariana T.; da Silva, Lucília P.; Santos, Tírcia C.; Pirraco, Rogério P.; Correlo, Vitor M.; Marques, Alexandra P.; Reis, Rui L.. "Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing". Tissue Engineering Part A 20 9-10 (2014): 1369-1378. http://dx.doi.org/10.1089/ten.tea.2013.0460. 10.1089/ten.tea.2013.0460 Pirraco, Rogério P.; Iwata, Takanori; Yoshida, Toshiyuki; Marques, Alexandra P.; Yamato, Masayuki; Reis, Rui L.; Okano, Teruo. "Endothelial cells enhance the in vivo bone-forming ability of osteogenic cell sheets". Laboratory Investigation 94 6 (2014): 663-673. http://dx.doi.org/10.1038/labinvest.2014.55. 10.1038/labinvest.2014.55 Zonari, Alessandra; Cerqueira, Mariana T.; Novikoff, Silviene; Goes, Alfredo M.; Marques, Alexandra P.; Correlo, Vitor M.; Reis, Rui L.. "Poly(hydroxybutyrate-co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement". Macromolecular Bioscience 14 7 (2014): 977-990. http://dx.doi.org/10.1002/mabi.201400005. 10.1002/mabi.201400005 Popa, Elena G.; Carvalho, Pedro P.; Dias, Ana F.; Santos, Tírcia C.; Santo, Vitor E.; Marques, Alexandra P.; Viegas, Carlos A.; et al. "Evaluation of the in vitro and in vivo biocompatibility of carrageenan-based hydrogels". Journal of Biomedical Materials Research Part A 102 11 (2014): 4087-4097. http://dx.doi.org/10.1002/jbm.a.35081. 10.1002/jbm.a.35081 Cerqueira, Mariana T.; Frias, Ana M.; Reis, Rui L.; Marques, Alexandra P.. "Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures". Stem Cells and Development 23 1 (2014): 34-43. http://dx.doi.org/10.1089/scd.2013.0038. 10.1089/scd.2013.0038 Almeida, Lília R.; Martins, Ana R.; Fernandes, Emanuel M.; Oliveira, Mariana B.; Mano, João F.; Correlo, Vitor M.; Pashkuleva, Iva; et al. "Errata to: “New biotextiles for tissue engineering: Development, characterization and in vitro cellular viability” [Acta Biomaterialia 9 (2013) 8167–8181]". Acta Biomaterialia 9 11 (2013): 9241. http://dx.doi.org/10.1016/j.actbio.2013.08.028. 10.1016/j.actbio.2013.08.028 Cerqueira, Mariana T.; Pirraco, Rogério P.; Santos, Tircia C.; Rodrigues, Daniel B.; Frias, Ana M.; Martins, Ana R.; Reis, Rui L.; Marques, Alexandra P.. "Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds". Biomacromolecules 14 11 (2013): 3997-4008. http://dx.doi.org/10.1021/bm4011062. 10.1021/bm4011062 Rodríguez-Valencia, Cosme; Pereiro, Iago; Pirraco, Rogelio P.; López-Álvarez, Miriam; Serra, Julia; González, Pío; Marques, Alexandra P.; Reis, Rui L.. "Human mesenchymal stem cells response to multi-doped silicon-strontium calcium phosphate coatings". Journal of Biomaterials Applications 28 9 (2013): 1397-1407. http://dx.doi.org/10.1177/0885328213510056. 10.1177/0885328213510056 Lima, Maria J.; Pirraco, Rogério P.; Sousa, Rui A.; Neves, Nuno M.; Marques, Alexandra P.; Bhattacharya, Mrinal; Correlo, Vitor M.; Reis, Rui L.. "Bottom-up approach to construct microfabricated multi-layer scaffolds for bone tissue engineering". Biomedical Microdevices 16 1 (2013): 69-78. http://dx.doi.org/10.1007/s10544-013-9806-4. 10.1007/s10544-013-9806-4 Almeida, Lília R.; Martins, Ana R.; Fernandes, Emanuel M.; Oliveira, Mariana B.; Correlo, Vitor M.; Pashkuleva, Iva; Marques, Alexandra P.; et al. "New biotextiles for tissue engineering: Development, characterization and in vitro cellular viability". Acta Biomaterialia 9 9 (2013): 8167-8181. http://dx.doi.org/10.1016/j.actbio.2013.05.019. 10.1016/j.actbio.2013.05.019 Duarte, Ana Rita C.; Santo, Vitor E.; Alves, Anabela; Silva, Simone S.; Moreira-Silva, Joana; Silva, Tiago H.; Marques, Alexandra P.; et al. "Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine". The Journal of Supercritical Fluids 79 (2013): 177-185. http://dx.doi.org/10.1016/j.supflu.2013.01.004. 10.1016/j.supflu.2013.01.004 Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P.. "Wound Healing Microenvironmental Cues: From Tissue Analogs to Skin Regeneration". Current Tissue Engineering 2 2 (2013): 145-153. http://dx.doi.org/10.2174/2211542011302020005. 10.2174/2211542011302020005 Silva, Simone S.; Popa, Elena G.; Gomes, Manuela E.; Cerqueira, Mariana T.; Marques, Alexandra P.; Caridade, Sofia G.; Teixeira, P.; et al. "An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine". Acta Biomaterialia 9 6 (2013): 6790-6797. http://dx.doi.org/10.1016/j.actbio.2013.02.027. 10.1016/j.actbio.2013.02.027 Gaharwar, Akhilesh K.; Mihaila, Silvia M.; Swami, Archana; Patel, Alpesh; Sant, Shilpa; Reis, Rui L.; Marques, Alexandra P.; Gomes, Manuela E.; Khademhosseini, Ali. "Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells". Advanced Materials 25 24 (2013): 3329-3336. http://dx.doi.org/10.1002/adma.201300584. 10.1002/adma.201300584 Santos, Tírcia C.; Morton, Tatjana J.; Moritz, Martina; Pfeifer, Sabine; Reise, Kathrin; Marques, Alexandra P.; Castro, António G.; Reis, Rui L.; van Griensven, Martijn. "Vascular Endothelial Growth Factor and Fibroblast Growth Factor-2 Incorporation in Starch-Based Bone Tissue-Engineered Constructs Promote theIn VivoExpression of Neovascularization Mediators". Tissue Engineering Part A 19 7-8 (2013): 834-848. http://dx.doi.org/10.1089/ten.tea.2010.0741. 10.1089/ten.tea.2010.0741 Pirraco, Rogério P.; Melo-Ferreira, Bruno; Santos, Tircia C.; Frias, Ana M.; Marques, Alexandra P.; Reis, Rui L.. "Adipose stem cell-derived osteoblasts sustain the functionality of endothelial progenitors from the mononuclear fraction of umbilical cord blood". Acta Biomaterialia 9 2 (2013): 5234-5242. http://dx.doi.org/10.1016/j.actbio.2012.09.013. 10.1016/j.actbio.2012.09.013 Mihaila, Silvia M.; Frias, Ana M.; Pirraco, Rogério P.; Rada, Tommaso; Reis, Rui L.; Gomes, Manuela E.; Marques, Alexandra P.. "Human Adipose Tissue-Derived SSEA-4 Subpopulation Multi-Differentiation Potential Towards the Endothelial and Osteogenic Lineages". Tissue Engineering Part A 19 1-2 (2013): 235-246. http://dx.doi.org/10.1089/ten.tea.2012.0092. 10.1089/ten.tea.2012.0092 Ferreira, Daniela S.; Marques, Alexandra P.; Reis, Rui L.; Azevedo, Helena S.. "Hyaluronan and self-assembling peptides as building blocks to reconstruct the extracellular environment in skin tissue". Biomaterials Science 1 9 (2013): 952-964. http://dx.doi.org/10.1039/c3bm60019j. 10.1039/c3bm60019j Mihaila, Silvia M.; Gaharwar, Akhilesh K.; Reis, Rui L.; Marques, Alexandra P.; Gomes, Manuela E.; Khademhosseini, Ali. "PhotocrosslinkableKappa-Carrageenan Hydrogels for Tissue Engineering Applications". Advanced Healthcare Materials 2 6 (2012): 895-907. http://dx.doi.org/10.1002/adhm.201200317. 10.1002/adhm.201200317 Pirraco, Rogério P.; Cerqueira, Mariana T.; Reis, Rui L.; Marques, Alexandra P.. "Fibroblasts regulate osteoblasts through gap junctional communication". Cytotherapy 14 10 (2012): 1276-1287. http://dx.doi.org/10.3109/14653249.2012.701006. 10.3109/14653249.2012.701006 Mendes, Luís F.; Pirraco, Rogério P.; Szymczyk, Wojciech; Frias, Ana M.; Santos, Tírcia C.; Reis, Rui L.; Marques, Alexandra P.. "Perivascular-Like Cells Contribute to the Stability of the Vascular Network of Osteogenic Tissue Formed from Cell Sheet-Based Constructs". PLoS ONE 7 7 (2012): e41051. http://dx.doi.org/10.1371/journal.pone.0041051. 10.1371/journal.pone.0041051 Cerqueira, Mariana T.; Marques, Alexandra P.; Reis, Rui L.. "Using Stem Cells in Skin Regeneration: Possibilities and Reality". Stem Cells and Development 21 8 (2012): 1201-1214. http://dx.doi.org/10.1089/scd.2011.0539. 10.1089/scd.2011.0539 Pirraco, Rogério P.; Reis, Rui L.; Marques, Alexandra P.. "Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs". Journal of Tissue Engineering and Regenerative Medicine 7 5 (2012): 392-400. http://dx.doi.org/10.1002/term.535. 10.1002/term.535 Silva, Simone S.; Santos, Tírcia C.; Cerqueira, Mariana T.; Marques, Alexandra P.; Reys, Lara L.; Silva, Tiago H.; Caridade, Sofia G.; Mano, João F.; Reis, Rui L.. "The use of ionic liquids in the processing of chitosan/silk hydrogels for biomedical applications". Green Chemistry 14 5 (2012): 1463. http://dx.doi.org/10.1039/c2gc16535j. 10.1039/c2gc16535j Martins, Albino; Alves da Silva, Marta L.; Faria, Susana; Marques, Alexandra P.; Reis, Rui L.; Neves, Nuno M.. "The Influence of Patterned Nanofiber Meshes on Human Mesenchymal Stem Cell Osteogenesis". Macromolecular Bioscience 11 7 (2011): 978-987. http://dx.doi.org/10.1002/mabi.201100012. 10.1002/mabi.201100012 Rada, Tommaso; Santos, Tircia C.; Marques, Alexandra P.; Correlo, Vitor M.; Frias, Ana M.; Castro, António G.; Neves, Nuno M.; Gomes, Manuela E.; Reis, Rui L.. "Osteogenic differentiation of two distinct subpopulations of human adipose-derived stem cells: an in vitro and in vivo study". Journal of Tissue Engineering and Regenerative Medicine 6 1 (2011): 1-11. http://dx.doi.org/10.1002/term.388. 10.1002/term.388 Pirraco, Rogério P.; Obokata, Haruko; Iwata, Takanori; Marques, Alexandra P.; Tsuneda, Satoshi; Yamato, Masayuki; Reis, Rui L.; Okano, Teruo. "Development of Osteogenic Cell Sheets for Bone Tissue Engineering Applications". Tissue Engineering Part A 17 11-12 (2011): 1507-1515. https://doi.org/10.1089/ten.tea.2010.0470. DOI 10.1089/ten.tea.2010.0470 Santos, Tircia C.; Marques, Alexandra P.; Höring, B.; Martins, Ana R.; Tuzlakoglu, Kadriye; Castro, António G.; van Griensven, Martijn; Reis, Rui L.. "In vivo short-term and long-term host reaction to starch-based scaffolds". Acta Biomaterialia 6 11 (2010): 4314-4326. http://dx.doi.org/10.1016/j.actbio.2010.06.020. 10.1016/j.actbio.2010.06.020 Santos, Tírcia C.; Marques, Alexandra P.; Silva, Simone S.; Oliveira, Joaquim M.; Mano, João F.; Castro, António G.; van Griensven, Martijn; et al. "Chitosan Improves the Biological Performance of Soy-Based Biomaterials". Tissue Engineering Part A 16 9 (2010): 2883-2890. http://dx.doi.org/10.1089/ten.tea.2010.0114. Publicado • 10.1089/ten.tea.2010.0114 Martins, Albino; Duarte, Ana Rita C.; Faria, Susana; Marques, Alexandra P.; Reis, Rui L.; Neves, Nuno M.. "Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality". Biomaterials 31 22 (2010): 5875-5885. http://dx.doi.org/10.1016/j.biomaterials.2010.04.010. 10.1016/j.biomaterials.2010.04.010 Salgado, António J.; Oliveira, Joaquim M.; Pirraco, Rogério P.; Pereira, Vitor H.; Fraga, Joana S.; Marques, Alexandra P.; Neves, Nuno M.; et al. "Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles in Central Nervous Systems-Regenerative Medicine: Effects on Neuron/Glial Cell Viability and Internalization Efficiency". Macromolecular Bioscience 10 10 (2010): 1130-1140. http://dx.doi.org/10.1002/mabi.201000005. 10.1002/mabi.201000005 Martins, Albino; Pinho, Elizabete D.; Correlo, Vitor M.; Faria, Susana; Marques, Alexandra P.; Reis, Rui L.; Neves, Nuno M.. "Biodegradable Nanofibers-Reinforced Microfibrous Composite Scaffolds for Bone Tissue Engineering". Tissue Engineering Part A 16 12 (2010): 3599-3609. https://doi.org/10.1089/ten.tea.2009.0779. DOI 10.1089/ten.tea.2009.0779 Oliveira, Joaquim T.; Santos, Tircia C.; Martins, Luis; Picciochi, Ricardo; Marques, Alexandra P.; Castro, António G.; Neves, Nuno M.; Mano, João F.; Reis, Reis L.. "Gellan Gum Injectable Hydrogels for Cartilage Tissue Engineering Applications: In Vitro Studies and Preliminary In Vivo Evaluation". Tissue Engineering Part A 16 1 (2010): 343-353. https://doi.org/10.1089/ten.tea.2009.0117. DOI 10.1089/ten.tea.2009.0117 Pirraco, Rogério P.; Marques, Alexandra. P.; Reis, Rui L.. "Cell interactions in bone tissue engineering". Journal of Cellular and Molecular Medicine 14 1-2 (2009): 93-102. http://dx.doi.org/10.1111/j.1582-4934.2009.01005.x. 10.1111/j.1582-4934.2009.01005.x Oliveira, João T.; Santos, Tircia C.; Martins, Luis; Silva, Marina A.; Marques, Alexandra P.; Castro, António G.; Neves, Nuno M.; Reis, Rui L.. "Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously implanted in nude mice". Journal of Tissue Engineering and Regenerative Medicine 3 7 (2009): 493-500. http://dx.doi.org/10.1002/term.184. 10.1002/term.184 Pashkuleva, Iva; Marques, Alexandra P.; Vaz, Filipe; Reis, Rui L.. "Surface modification of starch based biomaterials by oxygen plasma or UV-irradiation". Journal of Materials Science: Materials in Medicine 21 1 (2009): 21-32. http://dx.doi.org/10.1007/s10856-009-3831-0. 10.1007/s10856-009-3831-0 Martins, Albino; Chung, Sangwon; Pedro, Adriano J.; Sousa, Rui A.; Marques, Alexandra P.; Reis, Rui L.; Neves, Nuno M.. "Hierarchical starch-based fibrous scaffold for bone tissue engineering applications". Journal of Tissue Engineering and Regenerative Medicine 3 1 (2009): 37-42. http://dx.doi.org/10.1002/term.132. 10.1002/term.132 Martins, Albino; Pinho, Elizabete D.; Faria, Susana; Pashkuleva, Iva; Marques, Alexandra P.; Reis, Rui L.; Neves, Nuno M.. "Surface modification of electrospun polycaprolactone nanofiber meshes by plasma treatment to enhance biological performance". Small 5 10 (2009): 1195-1206. https://doi.org/10.1002/smll.200801648. 10.1002/smll.200801648 López-Álvarez, Miriam; Solla, E. L.; González, Pio; Serra, Julia; León, Betty; Marques, Alexandra P.; Reis, Rui L.. "Silicon–hydroxyapatite bioactive coatings (Si–HA) from diatomaceous earth and silica. Study of adhesion and proliferation of osteoblast-like cells". Journal of Materials Science: Materials in Medicine 20 5 (2008): 1131-1136. http://dx.doi.org/10.1007/s10856-008-3658-0. 10.1007/s10856-008-3658-0 Oliveira, Joaquim M.; Kotobuki, Noriko; Marques, Alexandra P.; Pirraco, Rogério P.; Benesch, Johan; Hirose, Motohiro; Costa, Silgia A.; et al. "Cover Picture: Surface Engineered Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles for Intracellular Targeting (Adv. Funct. Mater. 12/2008)". Advanced Functional Materials 18 12 (2008): http://dx.doi.org/10.1002/adfm.200890045. 10.1002/adfm.200890045 Oliveira, Joaquim M.; Kotobuki, Noriko; Marques, Alexandra P.; Pirraco, Rogério P.; Benesch, Johan; Hirose, Motohiro; Costa, Silgia A.; et al. "Surface Engineered Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles for Intracellular Targeting". Advanced Functional Materials 18 12 (2008): 1840-1853. http://dx.doi.org/10.1002/adfm.200800165. 10.1002/adfm.200800165 Coutinho, Daniela F.; Pashkuleva, Iva H.; Alves, Catarina M.; Marques, Alexandra P.; Neves, Nuno M.; Reis, Rui L.. "The Effect of Chitosan on the In Vitro Biological Performance of Chitosan-Poly(butylene succinate) Blends". Biomacromolecules 9 4 (2008): 1139-1145. http://dx.doi.org/10.1021/bm701268s. 10.1021/bm701268s Balmayor, Elizabeth R.; Tuzlakoglu, Kadriye; Marques, Alexandra P.; Azevedo, Helena S.; Reis, Rui L.. "A novel enzymatically-mediated drug delivery carrier for bone tissue engineering applications: combining biodegradable starch-based microparticles and differentiation agents". Journal of Materials Science: Materials in Medicine 19 4 (2008): 1617-1623. http://dx.doi.org/10.1007/s10856-008-3378-5. 10.1007/s10856-008-3378-5 Santos, Tircia C.; Marques, Alexandra P.; Silva, Simone S.; Oliveira, Joaquim M.; Mano, João F.; Castro, António G.; Reis, Rui L.. "In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes". Journal of Biotechnology 132 2 (2007): 218-226. http://dx.doi.org/10.1016/j.jbiotec.2007.07.497. 10.1016/j.jbiotec.2007.07.497 Mano, João F.; Silva, Gabriela A.; Azevedo, Helena S.; Malafaya, Patricia B.; Sousa, Rui A.; Silva, Simone S.; Boesel, Luciano F.; et al. "Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends". Journal of The Royal Society Interface 4 17 (2007): 999-1030. http://dx.doi.org/10.1098/rsif.2007.0220. 10.1098/rsif.2007.0220 López-Pérez, Paula M.; Marques, Alexandra P.; Silva, Ricardo M. P. da; Pashkuleva, Iva; Reis, Rui L.. "Effect of chitosan membrane surface modification via plasma induced polymerization on the adhesion of osteoblast-like cells". Journal of Materials Chemistry 17 38 (2007): 4064. http://dx.doi.org/10.1039/b707326g. 10.1039/b707326g Costa, David; Marques, Alexandra P.; Reis, Rui L.; Lima, José L.F.C.; Fernandes, Eduarda. "Inhibition of human neutrophil oxidative burst by pyrazolone derivatives". Free Radical Biology and Medicine 40 4 (2006): 632-640. http://dx.doi.org/10.1016/j.freeradbiomed.2005.09.017. 10.1016/j.freeradbiomed.2005.09.017 Marques, Alexandra P.; Reis, Rui L.; Hunt, John A.. "The effect of starch-based biomaterials on leukocyte adhesion and activation in vitro". Journal of Materials Science: Materials in Medicine 16 11 (2005): 1029-1043. http://dx.doi.org/10.1007/s10856-005-4757-9. 10.1007/s10856-005-4757-9 Marques, Alexandra P.; Cruz, Helder R.; Coutinho, Olga P.; Reis, Rui L.. "Effect of starch-based biomaterials on the in vitro proliferation and viability of osteoblast-like cells". Journal of Materials Science: Materials in Medicine 16 9 (2005): 833-842. http://dx.doi.org/10.1007/s10856-005-3580-7. 10.1007/s10856-005-3580-7 Marques, Alexandra P.; Reis, Rui L.; Hunt, John A.. "An In Vivo Study of the Host Response to Starch-Based Polymers and Composites Subcutaneously Implanted in Rats". Macromolecular Bioscience 5 8 (2005): 775-785. http://dx.doi.org/10.1002/mabi.200500010. 10.1002/mabi.200500010 Marques, Alexandra P.; Reis, Rui L.. "Hydroxyapatite reinforcement of different starch-based polymers affects osteoblast-like cells adhesion/spreading and proliferation". Materials Science and Engineering: C 25 2 (2005): 215-229. http://dx.doi.org/10.1016/j.msec.2005.01.013. 10.1016/j.msec.2005.01.013 Pashkuleva, Iva; Marques, Alexandra P.; Vaz, Filipe; Reis, Rui L.. "Surface modification of starch based blends using potassium permanganate-nitric acid system and its effect on the adhesion and proliferation of osteoblast-like cells". Journal of Materials Science: Materials in Medicine 16 1 (2005): 81-92. http://dx.doi.org/10.1007/s10856-005-6450-4. 10.1007/s10856-005-6450-4 Marques, Alexandra P.; Reis, Rui L.; Hunt, John A.. "Cytokine secretion from mononuclear cells culturedin vitro with starch-based polymers and poly-L-lactide". Journal of Biomedical Materials Research 71A 3 (2004): 419-429. http://dx.doi.org/10.1002/jbm.a.30155. 10.1002/jbm.a.30155 Marques, Alexandra P.; Reis, Rui L.; Hunt, John A.. "Journal of Materials Science: Materials in Medicine". Journal of Materials Science: Materials in Medicine 14 2 (2003): 167-173. http://dx.doi.org/10.1023/a:1022028114896. 10.1023/a:1022028114896 Marques, A.P.; Reis, R.L.; Hunt, J.A.. "The biocompatibility of novel starch-based polymers and composites: in vitro studies". Biomaterials 23 6 (2002): 1471-1478. http://dx.doi.org/10.1016/s0142-9612(01)00272-1. 10.1016/s0142-9612(01)00272-1
Capítulo de livro	Reis, Daniel P.; Gasperini, Luca; Marques, Alexandra P.. "Decellularized matrices for bioink development". In 3D Printing and Bioprinting for Pharmaceutical and Medical Devices Applications, 123-145. Boca Raton, Estados Unidos: CRC Press, 2023. Publicado Abreu, Carla M.; Gasperini, Luca; Marques, Alexandra P.. "Biofabrication technologies in hair neoformation". In Hair Follicle Regeneration, editado por Jimenez, F.; Higgins, C., 255-274. Cham, Suiça: Springer Nature, 2022. Publicado Soares, Ana I.; Reis, Rui L.; Marques, Alexandra P.. "3D in vitro cutaneous melanoma models". In Biomaterials for 3D Tumor Modeling, editado por Kundu, Subhas; Rui L. Reis, 287-303. Amsterdam, Países Baixos: Elsevier, 2020. 10.1016/b978-0-12-818128-7.00013-7 Gasperini, Luca; Marques, Alexandra P.; Reis, Rui L.. "Microfluidics for Processing of Biomaterials". In Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models, editado por Joaquim M Oliveira; Rui L Reis, 15-25. Cham, Suiça: Springer International Publishing, 2020. 10.1007/978-3-030-36588-2_2 da Silva, Lucília P.; Cerqueira, Mariana T.; Marques, Alexandra P.. "Regeneration Using Tissue Engineered Skin Strategies". In Therapeutic Dressings and Wound Healing Applications, editado por Boateng, Joshua, 255-289. Chichester, Reino Unido: Wiley-VCH, 2020. 10.1002/9781119433316 Fernandes, Maria G.; da Silva, Lucília P.; Marques, Alexandra P.. "Skin Mechanobiology and Biomechanics: From Homeostasis to Wound Healing". In Advances in Biomechanics and Tissue Regeneration, editado por Mohamed H. Doweidar, 343-360. Oxford, Reino Unido: Academic Press, 2019. 10.1016/b978-0-12-816390-0.00017-0 Carvalho, Andreia F.; Reis, Rui L.; Marques, Alexandra P.. "Endothelial Progenitor Cells and Their Niches". In Encyclopedia of Tissue Engineering and Regenerative Medicine, editado por Rui L. Reis; Manuela E. Gomes, 423-434. Oxford, Reino Unido: Academic Press, 2019. 10.1016/b978-0-12-801238-3.11288-7 Canadas, Raphaël F.; Pirraco, Rogério P.; Oliveira, J. Miguel; Reis, Rui L.; Marques, Alexandra P.. "Stem Cells for Osteochondral Regeneration". In Osteochondral Tissue Engineering, editado por Joaquim M Oliveira; Sandra Pina; Rui L. Reis; Julio San Roman, 219-240. Cham, Suiça: Springer International Publishing, 2018. 10.1007/978-3-319-76735-2_10 Canadas, Raphaël F.; Marques, Alexandra P.; Reis, Rui L.; Oliveira, J. Miguel. "Bioreactors and Microfluidics for Osteochondral Interface Maturation". In Osteochondral Tissue Engineering, editado por Joaquim M Oliveira; Sandra Pina; Rui L Reis; Julio San Roman, 395-420. Cham, Suiça: Springer International Publishing, 2018. 10.1007/978-3-319-76735-2_18 Lago, M.E.L.; Cerqueira, M.T.; Pirraco, R.P.; Reis, R.L.; Marques, A.P.; Lago, Manuela E.L.; Cerqueira, Mariana T.; et al. "Skin in vitro models to study dermal white adipose tissue role in skin healing". In Skin Tissue Models, editado por Alexandra P. Marques; Mariana T. Cerqueira; Rogério P. Pirraco; Rui L. Reis, 327-352. Boston, Estados Unidos: Academic Press, 2018. 10.1016/b978-0-12-810545-0.00014-0 Canadas, Raphaël F.; Pina, Sandra; Marques, Alexandra P.; Oliveira, Joaquim M.; Reis, Rui L.. "Cartilage and Bone Regeneration—How Close Are We to Bedside?". In Translating Regenerative Medicine to the Clinic, editado por J Laurence; P Batista; A Atala, 89-106. San Diego, Estados Unidos: Academic Press, 2016. 10.1016/b978-0-12-800548-4.00007-3 Costa, M.; Pirraco, R.P.; Cerqueira, M.T.; Reis, R.L.; Marques, A.P.. "Growth factor-free pre-vascularization of cell sheets for tissue engineering". In Methods in Molecular Biology, Stem Cell Dynamics and Heterogeneity, editado por K Turksen, 219-226. New York, Estados Unidos: Humana Press, 2016. 10.1007/7651_2016_362 Mihaila, S. M.; Reis, R. L.; Marques, Alexandra P. ; Gomes, M. E.. "Hydrogels in Bone Tissue Engineering: A Multi-Parametric Approach". In Gels Handbook: Fundamentals, Properties and Applications, editado por Utkan Demirci; Ali Khademhosseini, 165-197. Singapura: World Scientific Publishing Co, 2016. Canadas, Raphaël F.; Marques, Alexandra P.; Reis, Rui Luís; Oliveira, Joaquim Miguel. "Osteochondral Tissue Engineering and Regenerative Strategies". In Regenerative Strategies for the Treatment of Knee Joint Disabilities, editado por Joaquim M Oliveira; Rui L Reis, 213-233. Cham, Suiça: Springer International Publishing, 2016. 10.1007/978-3-319-44785-8_11 da Silva, L.P.; Cerqueira, M.T.; Correlo, V.M.; Reis, R.L.; Marques, A.P.. "Engineered hydrogel-based matrices for skin wound healing". In Wound Healing Biomaterials, editado por M. S. Ågren, 227-250. Duxford, Reino Unido: Woodhead Publishing, 2016. 10.1016/b978-1-78242-456-7.00011-8 Cerqueira, Mariana T.; Frias, Ana M.; Reis, Rui L.; Marques, Alexandra P.. "Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin". In Methods in Molecular Biology, editado por K. Turksen, 1-9. New York, Estados Unidos: Humana Press, 2013. 10.1007/978-1-62703-330-5_1 Pirraco, R. P.; Yamato, M.; Akiyama, Y.; Nagase, K.; Nakayama, M.; Marques, Alexandra; Reis, R. L.; Okano, T.. "Responsive Polymer Coatings for Smart Applications in Chromatography, Drug Delivery Systems, and Cell Sheet Engineering". In Intelligent Surfaces in Biotechnology, editado por H. M. Grandin; M. Textor, 321-354. Hoboken, Estados Unidos: John Wiley & Sons, Inc., 2012. 10.1002/9781118181249.ch9 Martins, A.; Sangwon, C.; Caridade, S. G.; Mano, J. F.; Sousa, R. A.; Marques, Alexandra P. ; Reis, R. L.; Neves, N. M.. "Hierarchical Starch-Based Fibrous Scaffold for Bone Tissue Engineering Applications". In Computer Aided Biomanufacturing, editado por R. Narayan; P. Calvert, 32-53. Berlin, Alemanha: Wiley-VCH, 2011. Marques, Alexandra; Pirraco, R. P.; Reis, R. L.. "Biocompatibility of starch-based polymers". In Natural-based Polymers for Biomedical Applications, editado por Rui L Reis; Nuno M Neves; João F Mano; Manuela E. Gomes; Alexandra P. Marques; Helena S Azevedo, 738-760. Cambridge, Reino Unido: Woodhead Publishing Limited, 2008. 10.1533/9781845694814.6.738 Santos, T. C.; Marques, Alexandra; Reis, R. L.. "In vivo tissue response to natural-origin biomaterials". In Natural-Based Polymers for Biomedical Applications, editado por Rui L Reis; Nuno M Neves; João F. Mano; Manuela E. Gomes; Alexandra P. Marques; Helena S Azevedo, 683-698. Cambridge, Reino Unido: Woodhead Publishing Limited, 2008. 10.1533/9781845694814.6.683 Azevedo, Helena S.; Gomes, Manuela E.; Malafaya, Patricia B.; Marques, Alexandra P. ; Salgado, António J.; Reis, Rui L.. "Natural Origin Degradable Polymers in Biomedical Applications". In Handbook of Biodegradable Polymeric Materials and Their Applications, editado por S. K. Mallapragada; B. Narasinmhan, 13-31. Los Angeles, Estados Unidos: American Scientific Publishers, 2006. Silva, G. A.; Alves, C. M.; Marques, Alexandra; Gomes, M. E.; Coutinho, O. P.; Reis, R. L.. "Cytotoxicity Screening of Biodegradable Polymeric Systems". In Biodegradable Systems for Tissue Engineering and Regenerative Medicine, editado por Rui L Reis; Julio San Roman, 339-353. Boca Raton, Estados Unidos: CRC Press, 2005. 10.1201/9780203491232.pt4 Marques, Alexandra; Hunt, J. A.; Reis, R. L.. "Natural-Origin Degradable Materials: the Barrier or the Passage through the Immune System?". In Biodegradable Systems for Tissue Engineering and Regenerative Medicine, editado por Rui L Reis; Julio San Roman, 355-375. Boca Raton, Estados Unidos: CRC Press, 2005. 10.1201/9780203491232.ch20 Marques, Alexandra; Hunt, J. A.; Reis, R. L.. "Mediation of the Cytokine Network in the Implantation of Orthopedic Devices". In Biodegradable Systems for Tissue Engineering and Regenerative Medicine, editado por Rui L Reis; Julio San Roman, 377-397. Boca Raton, Estados Unidos: CRC Press, 2005. 10.1201/9780203491232.ch21
Edição de livro	Gomes, Manuela E.; Marques, Alexandra P. ; De Filippo, R.. Encyclopedia of Tissue Engineering and Regenerative Medicine. Oxford, Reino Unido: Academic Press. 2019. Publicado Marques, Alexandra P. ; Cerqueira, Mariana T.; Pirraco, Rogério P.; Reis, Rui L.. Skin Tissue Models. San Diego, Estados Unidos: Academic Press. 2017. Publicado Reis, Rui L.; Neves, Nuno M.; Mano, Joao F.; Gomes, Manuela E.; Marques, Alexandra P. ; Azevedo, Helena S.. Handbook of Natural-based Polymers for Biomedical Applications. Cambridge, Reino Unido: Woodhead Publishing Limited. 2008. Publicado
Prefácio / Posfácio	Reis, R.L.; Neves, N.M.; Mano, J.F.; Gomes, M.E.; Marques, A.P.; Azevedo, H.S.. "Preface". Prefácio para Natural-Based Polymers for Biomedical Applications. 2008.
Resumo em conferência	Guimarães, Carlos F.; Gasperini, Luca; Rial, Raul S.; Marques, Alexandra P.; Reis, R L.. "3D flow-focusing microfluidic biofabrication of complex biomimetic architectures, from in-silico to in-vitro". Trabalho apresentado em Meeting European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Manchester, 2023. Publicado • 10.1089/ten.tea.2023.29043.abstracts Reis, Daniel P.; Malta, Mariana D.; da Silva, Lucilia P; Gasperini, Luca; Marques, Alexandra P.. "Dermal extracellular matrix extracts for wound healing: a pleiotropic trigger". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Manchester, 2023. Publicado • 10.1089/ten.tea.2023.29043.abstracts Chaves, Sara; Macedo, Joana; Reis, Daniel P.; da Silva, Lucilia P.; Marques, Alexandra P.. "Monocyte-derived macrophages and dermal fibroblasts-derived ECM making small talk". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Manchester, 2023. Publicado • 10.1089/ten.tea.2023.29043.abstracts Eltayari, Zahara; Gasperini, Luca; Marques, Alexandra P.. "The hurdles of Collagen shrinkage: A promising GelMA-based organotypic skin approach". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Manchester, 2023. Aceite para publicação • 10.1089/ten.tea.2023.29043.abstracts Soares, Ana I.; Cerqueira, Mariana T.; Pirraco, Rogério P.; Reis, Rui L.; Marques, Alexandra P.. "Self-organized pigmented and vascularized full skin tissue model for melanoma research". Trabalho apresentado em 11th World Congress on Alternatives and Animal Use in the Life Sciences, Maastricht, 2021. Publicado Malta, Mariana D.; Osório, Hugo; Guttmann-Gruber, C.; Kocher, T.; Carvalho, A.F.; Cerqueira, M.T.; Marques, Alexandra P.. "Extracellular matrix distinct signature among dystrophic epidermolysis bullosa variants,". Trabalho apresentado em 1st Global Congress on Epidermolysis Bullosa,, London, 2020. Canadas, R.F.; Oliveira, J.M.; Marques, A.P.; Reis, R.L.. "B-culture". Trabalho apresentado em 42nd Annual Meeting of the Society for Biomaterials, Seatle, 2019. Publicado Abreu, C. M.; Cerqueira, M. T.; Pirraco, R. P.; Reis, R. L.; Watt, F.; Marques, Alexandra P.. "Effect of EpSCs conditioned medium on dermal papilla cells". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Guimarães, C. F.; Gasperini, L.; Ribeiro, R. S.; Pinto, A. C.; Carvalho, A. F.; Marques, Alexandra P. ; Reis, R. L.. "Microfluidic fabrication of 3D biomaterial libraries for high-throughput screening stem cell responses". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Mandon, C. A.; da Silva, L. P.; Reis, R. L.; Marques, Alexandra P.. "TGF-b-Laden Polyssaccharide material to Modulate Fibroblast-to-Myofibroblast Transition for Scarring Control". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Gasperini, L.; Carvalho, A. F.; Ribeiro, R. S.; Marques, Alexandra P. ; Reis, R. L.. "Segmented microfibers as high-throughput platform to screen 3D cell-materials interactions". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Canadas, R. F.; Ren, T.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.; Demirci, U.. "Biochemical gradients to form a 3-D osteochondral in vitro model". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Ibanez, R.; Lemoine, R. M. F. M.; Reis, R. L.; Marques, Alexandra P. ; O'Brien, F. J.. "The development of a novel 3D bioprinted smart responsive dressing to treat skin scars". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Canadas, R.F.; Ren, T.; Tocchio, A.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.; Demirci, U.. "3-D structures with tunable porosity for in vitro anisotropic neural models". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Rhodes, 2019. Gasperini, L.; Carvalho, A. F.; Ribeiro, R.S.; Marques, Alexandra P. ; Reis, R. L.. "Microfluidic oil-free fabrication of multiple 3D platforms to screen cell-material interactions". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Davos, 2017. da Silva, L. P.; Lago, M. E. L.; Abreu, C.; Reis, R. L.; Marques, Alexandra P.. "Biofunctionalized Gellan Gum hydrogels as tailored platforms for skin regenerative purposes". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Davos, 2017. Lago, M. E. L.; Cerqueira, M. T.; Pirraco, R. P.; Costa, M.; Reis, R. L.; Marques, Alexandra P.. "Modulation of the secretory potential of in vitro adipose tissue microenvironments". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Davos, 2017. Ribeiro, S.; Carvalho, A. F.; Costa, M.; Cerqueira, M. T.; Marques, Alexandra P. ; Pirraco, R. P.; Reis, R. L.. "Hypothermic preservation of confluent Human Adipose Stem Cells". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Davos, 2017. Cerqueira, M. T.; Pirraco, R. P.; Reis, R. L.; Marques, Alexandra P.. "Unravelling The Cross Talk Between Cell Sheets Of Human Adipose Stem Cells And Keratinocytes". Trabalho apresentado em 29th Anual Congress of the Wound Healing Society, San Diego, 2017. Rodrigues, D. B.; Moreira, H. R.; Reis, R. L.; Marques, Alexandra P.. "In vitro 3D cell sheet-based model for unraveling scar pathophysiology". Trabalho apresentado em 53rd Congress of the European Societies of Toxicology (EUROTOX 2017), Bratislava, 2017. Ribeiro, Viviana; Silva-Correia, Joana; Morais, Alain; Correlo, Vitor M.; Marques, Alexandra P.; Ribeiro, Ana; Silva, Carla; et al. "Finely tuned fiber-based porous structures for bone tissue engineering applications". Trabalho apresentado em 10th World Biomaterials Congress, Montreal, 2016. 10.3389/conf.FBIOE.2016.01.02658 Canadas, R. F.; Vieira, S.; Vial, S.; Marques, Alexandra P. ; Reis, R. L.; Oliveira, J. M.. "Comparison of bilayered structures of gellan gum with and without incorporation of gold nanorods for osteochondral tissue engineering". Trabalho apresentado em 10th World Biomaterials Congress, Montreal, 2016. Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Rotational dual-chamber bioreactor to generate 3D tissue interface". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Uppsala, 2016. Pina, S.; Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Hierarchical ionic-doped scaffolds for osteochondral tissue engineering". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Uppsala, 2016. da Silva, L. P.; Oliveira, S.; Lago, M. E. L.; Cerqueira, M. T.; Pirraco, R. P.; Santos, T. C.; Reis, R. L.; Correlo, V. M.; Marques, Alexandra P.. "Natural melanin promotes the differentiation of an early epidermal cell fraction and the scavenging of ROS". Trabalho apresentado em Society for Investigative Dermatology (SID) Annual Meeting, Scottsdale, 2016. Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.; Demirci, U.. "Dynamic Platform To Recreate An Osteoarthritic 3D In Vitro Model". Trabalho apresentado em Meeting of the North American Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM), San Diego, 2016. Moreira, H. R.; Rodrigues, D. B.; Reis, R. L.; Marques, Alexandra P.. "Unravelling the path to create a cell sheet-based model of skin scar-like tissue". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Davos, 2016. Canadas, R. F.; Pereira, D. R.; Silva-Correia, J.; Viegas, C.; da Silva Morais, A.; Sousa, R. A.; Marques, Alexandra P. ; Reis, R. L.; Oliveira, J. M.. "In Vivo Performance of Gellan Gum-Based Structures: A Comparison Study Between Hydrogels and Spongy-Like Scaffolds for Osteochondral Tissue Regeneration". Trabalho apresentado em 39th Annual Meeting of the Society for Biomaterials, Charlotte, 2015. Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Rotational Dual Chamber Bioreactor for Interfaced Engineered Tissue Models". Trabalho apresentado em 39th Annual Meeting of the Society for Biomaterials, Charlotte, 2015. Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Rotational Dual-Chamber Bioreactor designed for Tissue Engineered Interfaces". Trabalho apresentado em 27th European Conference on Biomaterials, Krakow, 2015. Ribeiro, V.; Morais, A.; Correlo, V. M.; Marques, Alexandra P. ; Ribeiro, A.; Silva. C.; Durães, N.; et al. "Textile-Based Silk Scaffolds for Bone Tissue Engineering Applications". Trabalho apresentado em 27th European Conference on Biomaterials, 2015. Santos, T. C.; Rodrigues, D. B.; Cerqueira, M. T.; Pirraco, R. P.; Castro, A. G.; Reis, R. L.; Marques, Alexandra P.. "Adipose Tissue-derived Stem Cells do not Elicit Alloreactivity after Chondrogenic and Osteogenic Differentiation". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Cerqueira, M. T.; Pirraco, R. P.; Santos, T. C.; Reis, R. L.; Marques, Alexandra P.. "Skin-derived Cell-sheets as Powerful Tools to Engineer Skin Analogues". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Costa, M.; Cerqueira, M. T.; Rodrigues, D. B.; Santos, T. C.; Marques, Alexandra P. ; Pirraco, R. P.; Reis, R. L.. "Stromal Vascular Fraction Cell Sheets Angiogenic Potential for Tissue Engineering and Regenerative Medicine Applications". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. da Silva, L. P.; Cerqueira, M. T.; Pirraco, R. P.; Santos, T. C.; Reis, R. L.; Correlo, V. M.; Marques, Alexandra P.. "Gellan Gum-Hyaluronate Spongy-like Hydrogels Promote Angiogenesis in Hindlimb Ischemia". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Correia, C. R.; Pirraco, R. P.; Cerqueira, M. T.; Marques, Alexandra P. ; Reis, R. L.; Mano, J. F.. "Osteogenic Differentiation of Adipose Stem Cells by Endothelial Cells Co-culture within Liquified Capsules". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Bishi, D. K.; Gasperini, L.; Marques, Alexandra P. ; Mano, J. F.; Reis, R. L.. "Development of Janus Hydrogel Microcapsules as Novel Biomaterials-Stem Cells Construct for 3D Co-culture Applications". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Lago, M. E. L.; Cerqueira, M. T.; Pirraco, R. P.; Costa, M.; Reis, R. L.; Marques, Alexandra P.. "Adipogenic Cell Sheets to Recreate In Vitro Adipose Tissue Microenvironments". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Pereira, D. R.; Canadas, R. F.; Correia-Silva, J.; Marques, Alexandra P. ; Reis, R. L.; Oliveira, J. M.. "Acellular Gellan-gum based Bilayered Structures for the Regeneration of Osteochondral Defects: A Preclinical Study". Trabalho apresentado em 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Boston, 2015. Santos, T. C.; Pirraco, R. P.; Rodrigues, D. B.; da Silva, L. P.; Reis, R. L.; Marques, Alexandra P.. "Hind limb ischemia in type 1 diabetic mice as useful tool to evaluate the neovascularization of tissue engineering constructs". Trabalho apresentado em I Iberian Congress for Laboratory Animal Science, Caceres, 2015. Prata, F. P.; Cerqueira, M. T.; Moreira-Silva, J.; Pirraco, R. P.; Reis, R. L.; Marques, Alexandra P.. "Cryopreservation of Cell Sheets of Adipose Stem Cells: Limitations and Successes". Trabalho apresentado em Meeting of the North American Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM), Washington, 2014. Costa, M.; Cerqueira, M. T.; Rodrigues, D. B.; Santos, T. C.; Marques, Alexandra P. ; Pirraco, R. P.; Reis, R. L.. "Cells Sheets of Adipose Tissue Stromal Vascular Fraction as Vascularization Units for Tissue Engineering and Regenerative Medicine". Trabalho apresentado em Meeting of the North American Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM), Washington, 2014. Custódio, C.; Cerqueira, M. T.; Marques, Alexandra P. ; Reis, R. L.; Mano, J, F.. "Functional chitosan microcarriers for selective cell attachment and expansion". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Correira, C. R.; Pirraco, R. P.; Cerqueira, M. T.; Marques, Alexandra P. ; Reis, R. L.; Mano, J. F.. "Paracrine signalling between adipose tissue stem and microvascular endothelial cells within multilayered capsules trigger osteoblastogenesis". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Frias, A. M.; Correia, C.; Moreira, E. S.; Marques, M.; Marques, Alexandra P. ; Sousa, A. R.; Reis, R. L.. "Xeno-free cGMP isolation and cryopreservation of clinical grade stromal vascular fraction". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Oliveira, S.; Pirraco, R. P.; Marques, Alexandra P. ; Reis, R. L.; Mano, J. F.. "Layer-by-layer assembled nanocoatings of human platelet’s lysate and marine-origin polysaccharides trigger pro-angiogenic behavior". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Canadas, R. F.; Marques, Alexandra P. ; Reis, R. L.; Oliveira, J. M.. "Acellular bilayered scaffolds for osteochondral tissue regeneration". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Prata, M.; Moreira-Silva, J. M.; Marques, Alexandra P. ; Silva, T.; Reis, R. L.. "Chondrosia reniformis marine-sponge collagen membranes for skin re-epithelialization". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Zonari, A.; Paula, A. C. C.; Martins, T. M.; Boleoni, J. N.; Novikoff, S.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.; Goes, A. M.. "Scarring impairment by polyhydroxybutyrate-co-hydroxyvalerate bilayer structures-laden adipose stem cells". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Genoa, 2014. Mihaila, S. M.; Popa, E. G.; Reis, R. L.; Marques, Alexandra P. ; Gomes, M. E.. "3D hydrogel fibers based system to design heterotypic bone vascularization approaches". Trabalho apresentado em 37th Annual Meeting of the Society for Biomaterials, Boston, 2013. da Silva, L. P.; Cerqueira, M. T.; Sousa, R. A.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.. "Gellan Gum-Based Spongy-like Hydrogels Depict Improved Cellular Performance". Trabalho apresentado em 37th Annual Meeting of the Society for Biomaterials, Boston, 2013. Cerqueira, M. T.; da Silva, L. P.; Santos, T. C.; Pirraco, R. P.; Correlo, V. M.; Marques, Alexandra P. ; Reis, R. L.. "Pre-vascularized Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels improve Skin wound healing". Trabalho apresentado em 37th Annual Meeting of the Society for Biomaterials, Boston, 2013. Canadas, R. F.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Development of Novel Bilayered Structures to be Used as an Osteochondral In Vitro Model". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Ribeiro, V. P.; Ribeiro, A. S.; Silva, C. J.; Durães, N. F.; Bonifácio. G.; Marques, Alexandra P. ; Sousa, R. A.; Oliveira, A. L.; Reis, R. L.. "Silk-based 3D Biotextiles Support Human Adipose Derived Stem Cells Towards Osteogenic Differentiation". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Santos, T. C.; Rodrigues, D. B.; Cerqueira, M. T.; Silva, A. C.; Rodrigues, A. I.; Leonor, I. B.; Marques, Alexandra P. ; Castro, A. G.; Reis, R. L.. "Tissue engineered constructs based on human adipose tissue derived stem cells and starch-based scaffolds for allogeneic approaches in tissue engineering and regenerative medicine". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Berti, V. F.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.. "Semiconductor gellan gum based composite hydrogels for tissue engineering applications". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Pirraco, R. P.; Carvalho, F.; Reis, R. L.; Marques, Alexandra P.. "Dextran Sulphate and Ficcol Fail as Macromolecular Crowders to Enhance Extracellular Matrix Deposition". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Cerqueira, M.T.; da Silva, L. P.; Santos, T. C.; Pirraco, R. P.; Correlo, V. M.; Marques, Alexandra P. ; Reis, R. L.. "Co-cultured Adipose Tissue Cells within a Gellan Gum-Hyaluronic Acid matrix promote vascularization of full-thickness wounds". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Custódio, C. A.; Cerqueira, M. T.; Marques, Alexandra P. ; Reis, R. L.; Mano, J. F.. "Functional cell microcarriers - a new platform for cell separation and expansion". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Moreira-Silva, J.; Silva, T. H.; Prata, M. B.; Cerqueira, M. T.; Pirraco, R. P.; Giovine, M.; Marques, Alexandra P. ; Reis, R. L.. "Potential of marine sponge collagen coatings for skin regeneration strategies". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. Silva, S. S.; Popa, E. G.; Gomes, M. E.; Cerqueira, M. T.; Marques, Alexandra P. ; Caridade, S. G.; Mano, J. F.; Reis, R. L.. "Combination of aloe vera improves the biological performance of chitosan membranes for skin tissue repair". Trabalho apresentado em TERM STEM 2013, Guimaraes, 2013. da Silva, L. P.; Jha, A. K.; Correlo, V. M.; Marques, Alexandra P. ; Reis, R. L.; Healy, K. E.. "Functionalized Gellan Gum Hydrogels Potentiate Endothelial Cell Performance". Trabalho apresentado em 38th Annual Meeting of the Society for Biomaterials, Denver, 2013. Duarte, A. R.; Santo, V. E.; Alves, A.; Silva, S. S.; Moreira-Silva, J.; Silva, T. H.; Marques, Alexandra P. ; et al. "Unleashing the Potential of Supercritical Fluids for Polymer Processing in Tissue Engineering and Regenerative Medicine". Trabalho apresentado em 10th Internaional Symposium on Supercritical Fluids (ISSC), San Francisco, 2012. Zonari, A.; Cerqueira, M. T.; Novikoff, S.; Goes, A. M.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.. "Evaluation of the potential of Polyhydroxybutyrate-co-hydroxyvalerate bi-layered scaffolds for skin tissue engineering". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS, Vienna, 2012. Duarte, A. R.; Moreira-Silva, J.; Silva, T. H.; Osinga, R.; Ilan, M.; Marques, Alexandra P. ; Mano, J. F.; Reis, R. L.. "Marine sponges as natural scaffolds: decellularization by supercritical fluid technology and cellularization with osteoblasts for tissue engineering applications". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Vienna, 2012. Santos, T. C.; Cerqueira, M. T.; Silva, A. C.; Rodrigues, A. I.; Leonor, I. B.; Marques, Alexandra P. ; Castro, A. G.; Reis, R. L.. "Immunomodulatory potential of tissue engineered constructs based on human adipose tissue derived stem cells and starch-based scaffolds". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Vienna, 2012. Cerqueira, M. T.; da Silva, L. P.; Sousa, A. R.; Correlo, V. M.; Marques, Alexandra P. ; Reis, R. L.. "Human embryonic stem cell-derivatives in a hydrogel-based skin model". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Vienna, 2012. Mendes, L. F.; Pirraco, R. P.; Szymczyk, W.; Santos, T. C.; Frias, A.M.; Reis, R. L.; Marques, Alexandra P.. "Pericytes contribute to the stability of the vascular network of osteogenic tissue formed from Cell sheet-based constructs". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Vienna, 2012. Silva, B. L.; Cerqueira, S. R.; Fevereiro, J. P.; Pirraco, R. P.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.; Sousa, N.; Salgado, A. J.. "Hyaluronic acid/poly(amidoamine) dendrimer nanoparticles for central nervous system applications: In vitro and in vivo studies". Trabalho apresentado em 3rd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Vienna, 2012. Pirraco, R. P.; Marques, Alexandra P. ; Reis, R. L.. "Cell Sheet Engineering for reproducing the Bone Marrow Hematopoietic Stem Cell Niche". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Moreira-Silva, J.; Afonso, D.; Silva, T. H.; Volpato, F.; Marques, Alexandra P. ; Motta, A.; Mano, J. F.; Reis, R. L.; Migliaresi, C.. "Fish scales patterning guiding hASCs growth". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Santos, T. C.; Pirraco, R. P.; Frias, A. M.; Martins, A. R.; Reis, R. L.; Marques, Alexandra P.. "Improved regeneration of mice full-thickness excisional wounds by Human Adipose Stem Cells Cell-Sheets". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Manda-Guiba, M.; Oliveira, M. B.; Mano, J. F.; Marques, Alexandra P. ; Oliveira, J. M.; Correlo, V. M.; Reis, R. L.. "Gellan Gum – Hydroxyapatite composites hydrogels for Bone Tissue Engineering". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Canadas, R.; Pereira, D. R.; Silva-Correia, J.; Marques, Alexandra P. ; Oliveira, J. M.; Reis, R. L.. "Novel bilayered gellan gum/gellan gum-hydroxyapatite scaffolds for osteochondral tissue engineering applications". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Reys, L. L.; Silva, S. S.; Pirraco, R. P.; Marques, Alexandra P. ; Mano, J. F.; Silva, T. H.; Reis, R. L.. "Cartilage regeneration approach based on squid chitosan scaffolds: in-vitro assessment". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Ribeiro, V. P.; Martins, A. R.; Marques, Alexandra P. ; Bonifácio, G.; Oliveira, A. L.; Sousa, R. A.; Reis, R. L.. "Suitability of Silk-based 3D Biotextiles Seeded with Human Adipose-derived Stem Cells for a Bone Tissue Engineering Approach". Trabalho apresentado em TERM STEM 2012, Guimaraes, 2012. Santos, T. C.; Rodrigues, D. B.; Cerqueira, M. T.; Pirraco, R. P.; Marques, Alexandra P. ; Reis, R. L.. "Xenogeneic M2-polarization of Macrophages by Undifferentiated and Differentiated Adipose Tissue-derived Stem Cells". Trabalho apresentado em Meeting of the North American Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM), Washington, 2012. Pirraco, R.P.; Ferreira, B.; Santos, T.C.; Frias, A.M.; Cerqueira, M.T.; Marques, A.P.; Reis, R.L.. "Endothelial progenitors from umbilical cord blood supported by osteoblasts contribute to angiogenesis". Trabalho apresentado em 24th European Conference on Biomaterials, 2011. Santos, T. C.; Marques, Alexandra P. ; Castro, A. G.; van Griensven, M.; Reis, R. L.. "Host response to biomaterials evaluated through different implantation models". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Pirraco, R. P.; Iwata, T.; Marques, Alexandra P. ; Yamato, M.; Reis, R. L.; Okano, T.. "The potential of osteogenic cell sheets co-cultured with endothelial cells for Bone Tissue Engineering". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Monteiro, I. P.; Shukla, A.; Marques, Alexandra P. ; Hammond, P. T.; Reis, R. L.. "Single epidermal-dermal scaffold for the regeneration of full-thickness skin defects". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Cerqueira, M. T.; Frias, A. M.; Marques, Alexandra P. ; Reis, R. L.. "Boost of Epidermal Stem Cells from Adult Keratinocytes". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), 2011. Frias, A. M.; Resende, M. F.; Fernandes, S.; Barros, A.; Gomes, M. E.; Marques, Alexandra P. ; Neves, N. M.; Reis, R. L.. "An Innovative Serum-Free Culture System for Expansion and Osteogenic Differentiation of Adipose and Amniotic-derived Stem Cells". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Almeida, L. R.; Correlo, V. M.; Lisboa, P.; Martins, A. R.; Marques, Alexandra P. ; Ribeiro, A. S.; Silva, C.; et al. "Innovative 3D Biotextiles for Potencial Bone Tissue Engineering Applications". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Szymczyk, W.; Araújo, J. V.; Martins, A.; Correlo, V. M.; Neves, N. M.; Marques, Alexandra P. ; Reis, R. L.. "2D bi-layer scaffolds of polycaprolactone and chitosan ß-glycerol based film for blood vessel constructs". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. da Silva, L. P.; Cerqueira, M. T.; Oliveira, J. M.; Sousa, R. A.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.. "Novel Gellan Gum - Hyaluronan hydrogel formulations for tissue engineering applications". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Santos, T. C.; Martins, A. R.; Frias, A. M.; Marques, Alexandra P. ; Reis, R. L.. "Dendritic cells as relevant tools to predict the outcome of tissue engineering constructs". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Silva, S. S.; Santos, T. C.; Cerqueira, M. T.; Marques, Alexandra P. ; Andrade, S. G.; Mano, J. F.; Reis, R. L.. "Ionic liquids in novel processing ways to obtain chitosan/silk fibroin hydrogels for skin tissue engineering". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Ferreira, D. S.; Marques, Alexandra P. ; Reis, R. L.; Azevedo, H. S.. "Attachment and spreading of fibroblasts on self-assembling bioactive matrices". Trabalho apresentado em XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, 2011. Popa, E. G.; Carvalho, P. P.; Dias, A. F.; Santo, V. E.; Frias, A. M.; Marques, Alexandra P. ; Dias, I. R.; et al. "In vitro and in vivo biocompatibility evaluation of k-carrageenan hydrogels aimed at applications in regenerative medicine". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Granada, 2011. Pirraco, R. P.; Iwata, T.; Marques, Alexandra P. ; Yamato, M.; Reis, R. L.; Okano, T.. "Endothelial cells potentiate Cell Sheets Osteogenic Ability". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Granada, 2011. Ferreira, D. S.; Marques, Alexandra P. ; Reis, R. L.; Azevedo, H. S.. "Self-assembling biomimetic matrices: opportunities for research and therapies in skin regeneration". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Granada, 2011. Silva, S. S.; Duarte, A. R. C.; Santos, T. C.; Cerqueira, M. T.; Marques, Alexandra P. ; Oliveira, J. M.; Mano, J. F.; Reis, R. L.. "Integrated strategy using ionic liquids for design and processability of natural polymeric architectures for regenerative medicine". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Granada, 2011. Oliveira, J.T.; Picciochi, R.; Santos, T.C.; Malafaya, P.B.; Sousa, R.A.; Marques, A.P.; Castro, A.G.; et al. "Injectable gellan gum hydrogels as supports for cartilage tissue engineering applications: In vitro characterization and initial in vivo studies". Trabalho apresentado em 8th World Biomaterials Congress, Amsterdam, 2008. Salgado, A.J.; Oliveira, J.M.; Pereira, V.H.; Pirraco, R.; Marques, A.P.; Neves, N.M.; Mano, J.F.; Reis, R.L.; Sousa, N.. "Carboxymethyl-chitosan/poly(amidoamine) dendrimer nanoparticles as intracellular drug delivery systems in central nervous system regenerative medicine: Effects on neurons/glial cell viability/proliferation and internalization efficiency". Trabalho apresentado em 8th World Biomaterials Congress 2008, 2008. Santos, T. C.; Tuzlakoglu, K.; Morton, T.; Reise, K.; Marques, Alexandra P. ; Castro, A. G.; Redl, H.; et al. "In vivo evaluation of the suitability of starch-based scaffolds for bone tissue engineering constructs using Adipose Derived Adult Stem Cells and transgenic mice". Trabalho apresentado em 8th World Biomaterials Congress, Amsterdam, 2008. Publicado Santos, T. C.; Marques, Alexandra P. ; Silva, S. S.; Oliveira, J. M.; Mano, J. F.; Castro, A. G.; van Griensven, M.; Reis, R. L.. "Chitosan/soy-based membranes enhance wound reepithelialization in partial thickness skin wound". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Chung, S.; Martins, A.; Correlo, V. M.; Oliveira, J. T.; Marques, Alexandra P. ; Neves, N. M.; Mano, J. F.; Sousa, R. A.; Reis, R. L.. "Dependence of Cell Proliferation on the Morphology of Starch Based Scaffolds for Tissue Engineering". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Pirraco, R. P.; Yamato, M.; Marques, Alexandra P. ; Reis. R. L.; Okano, T.. "Development and characterization of osteogenic cell sheets in an in vivo model.". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Cerqueira, M. T.; Martins, A.; Rada, T.; Gomes, M. E.; Marques, Alexandra P. ; Neves, N. M.; Reis, R. L.. "Human Dermal Fibroblasts, Keratinocytes and Adipose Stem Cells Behaviour on Patterned Electrospun Nanofiber Meshes". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Oliveira, J. M.; Salgado, A. J.; Pirraco, R. P.; Pereira, V. H.; Fraga, J. S.; Marques, Alexandra P. ; Neves, N. M.; et al. "In Vitro Characterization on the Interactions Between Carboxymethyl-chitosan/Poly(amidoamine) Dendrimer Nanoparticles and Neurons/Glial Cells". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Oliveira, J. T.; Picchioci, R.; Santos, T. C.; Martins, L.; Pinto, L. G.; Malafaya, P. B.; Sousa, R. A.; et al. "Injectable Gellan Gum Hydrogels as Supports for Cartilage Tissue Engineering Applications". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Santos, T. C.; Marques, Alexandra P. ; Castro, A. G.; van Griensven, M.; Redl, H.; Reis, R. L.. "Long term in vivo performance of starch-based scaffolds". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), 2008. Martins, A.; Chung, S.; Pedro, A. J.; Sousa, R. A.; Marques, Alexandra P. ; Reis, R. L.; Neves, N. M.. "Novel Micro-Nanofibrous Multilayer Scaffold for Bone Tissue Engineering Applications". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), 2008. López-Álvarez, M.; Solla, E. L.; González, P.; Serra, J.; León, B.; Marques, Alexandra P. ; Reis, R. L.. "Silicon - Hydroxyapatite Bioactive Coatings (Si-HA) from Diatomaceous Earth and SiO2. Study of adhesion and proliferation of osteoblast-like cells". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Szymczyk, W.; Araújo, J. V.; Martins, A.; Pinho, E.; Neves, N. M.; Marques, Alexandra P. ; Reis, R. L.. "Co-culture of Endothelial and Smooth Muscle Cells for the Development of Blood Vessel Constructs". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Coutinho, D. F.; Pashkuleva, I. H.; Alves, C. M.; Marques, Alexandra P. ; Neves, N. M.; Reis, R. L.. "The presence of chitosan at the surface influences the interaction of Biomolecules and Cells with chitosan-poly(bultylene succinate) blend". Trabalho apresentado em Meeting of the European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU), Porto, 2008. Alves, C. M.; Marques, Alexandra P. ; Reis, R. L.; Hunt, J. A.. "Implanted Biodegradable Materials: The Behavior Of Biomolecules". Trabalho apresentado em XXXV Congress of the European Society for Artificial Organs (ESAO), Geneva, 2008. Marques, Alexandra P. ; Santos, T. C.; da Silva, R. M. P.; Silva, S. S.; Oliveira, J. M.; van Griensven, M.; Mano, J. F.; Redl, H.; Reis, R. L.. "Chitosan improves the in vivo biological response to soy-based biomaterials". Trabalho apresentado em Fall simposium of the Society for Biomaterials, Atlanta, 2008. Martins, A.; Pinho, E. D.; Malafaya, P. B.; Marques, Alexandra P. ; Reis, R. L.; Neves, N. M.. "Micro-Nano Composite Mesh Scaffold in mouse MPCs Osteogenic Differentiation.". Trabalho apresentado em 21st European Conference on Biomaterials, Brighton, 2007. Pirraco, R. P.; Marques, Alexandra P. ; Reis. R. L.. "Monocytes Stimulate Stem Cells Proliferation and Early Osteogenic Differentiation in a Co-culture System". Trabalho apresentado em 21st European Conference on Biomaterials, Brighton, 2007. Pirraco. R. P.; Marques, Alexandra P. ; Reis. R. L.. "Effect of human fibroblasts over the osteoblastic activity of human osteoblastic-like cells: role for cell-cell interactions.". Trabalho apresentado em 31st Annual Meeting of the Society for Biomaterials, Pittsburgh, 2006. Alves, C. M.; Marques, Alexandra P. ; Reis, R. L.; Hunt, J.A.. "In Vitro and In Vivo protein adsorption onto starch-based materials and the effect on inflammatory cell recruitment". Trabalho apresentado em 30th Annual Meeting of the Society for Biomaterials Memphis, Memphis, 2005. Alves, C. M.; Marques, Alexandra P. ; Reis, R. L.; Hunt, J. A.. "In vitro and in vivo analysis of protein interactions with different starch-based biomaterials.". Trabalho apresentado em ESAO-IFAO 2005 - XXXIII Meeting of the European Society for Artificial Organs (ESAO) together with the International Federation on Artificial Organs (IFAO), Bologna, 2005. Marques, A.P.; Reis, R.L.; Hunt, J.A.. "In vitro and in vivo inflammatory reaction to starch-based biomaterials. Cellular and chemical mediators.". Trabalho apresentado em 7th World Biomaterials Congress, Sydney, 2004.
Tese / Dissertação	Marques, Alexandra P.. "Biofunctionality and Immunocompatibility of Starch-Based Biomaterials". Doutoramento, Universidade do Minho, 2004.

Propriedade Intelectual

Patente

Canadas, R. F.; Oliveira, J. M.; Marques, Alexandra P. ; Reis, R. L.. 2017. "Rotational dual chamber bioreactor: methods and uses thereof".
da Silva, L. P.; Cerqueira, M. T.; Sousa, R. A.; Marques, Alexandra P. ; Correlo, V. M.; Reis, R. L.. 2017. "Gellan gum spongy-like hydrogel, its preparation and biomedical applications thereof". Estados Unidos.
Concedida/Emitida

Pedido provisório de patente

2021. "Multicompartment hydrogel fibre their preparation and uses thereof".
Protegido
2021. "Hydrogel-like particles, methods and uses thereof".
Protegido
2020. "Bioreactor for Tissue Engineering of Multi-tissue Structure and Manufacturing Method Thereof".
2020. "Gellan gum based inks, method of obtaining and uses thereof".
2019. "Method for distribution of active factors in an artificial tissue, products and uses thereof".
Protegido
2018. "Fibres with segments, their preparation and applications thereof".
Protegido
2015. "Marine-sponge type iv collagen membranes its production and biomedical applications thereof".
Divulgado
2015. "Multi-chamber bioreactor, methods and uses".
Protegido

Outros

Outra produção

Dermal Papilla Cells and Melanocytes Response to Physiological Oxygen Levels Depends on Their Interactions. 2020. Carla Abreu; Rui L Reis; Alexandra P Marques. https://doi.org/10.21203/rs.3.rs-53575/v1.
10.21203/rs.3.rs-53575/v1

Atividades

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2022/02/01 - Atual	Exploring 3D printing and dynamic culture platforms to understand the progression of human cutaneous squamous cell carcinoma Orientador	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal
2021/02/01 - Atual	Exploring stromal and immune cells axis in cutaneous squamous cell carcinoma progression Orientador	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal
2019/09/01 - Atual	Valorization of Cod (Gadus morhua) by-products by isolation of collagen and native ECM envisaging skin care and regeneration Coorientador	Terapias Avançadas para a Saúde (Doutoramento) Universidade do Minho, Portugal
2019/01/01 - Atual	The role of extracellular matrix in cutaneous squamous cell carcinoma development Orientador	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal Albert-Ludwigs-Universität Freiburg Medizinische Fakultät, Alemanha
2018/09/01 - Atual	Establishing a Dynamic in vitro culture system to enhance the functionality of 3D-Bioprinted skin-like constructs Orientador	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal
2016/09/01 - 2023/01/31	Novel platforms for vascularization in skin wound healing Orientador	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal
2017/09/01 - 2022/11/25	An Innovative Therapeutic Approach for Infected Chronic Wounds Coorientador	Ciências da Saúde (Doutoramento) Universidade do Minho, Portugal
2017/10/01 - 2021/12/12	The development of a novel 4D bioprinted smart responsive dressing to treat skin scars Coorientador	Engenharia de Tecidos (Doutoramento) Royal College of Surgeons in Ireland, Irlanda Universidade do Minho, Portugal
2015/09/01 - 2020/12/10	Strategies towards the recreation of a hair follicle regenerative microenvironment Orientador	Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal
2017/09/01 - 2018/09/01	Biofeature-tuned Gellan Gum Bioinks for 3D-Printing of Skin Analogues Orientador	Synthetic Biology and High-Throughput Biotechnology (Mestrado) Ecole supérieure de biotechnologie de Strasbourg, França
2014/04/01 - 2018/05/15	Novel Osteochondral 3D model as an in vitro technological platform for drugs screening: understanding the molecular and cellular changes during osteoarthritis progression Orientador	Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal Stanford University School of Medicine, Estados Unidos
2011/10/01 - 2016/10/13	Advance Gellan Gum-Based Hydrogels for the Treatment of Diabetic Foot Ulcerations Orientador	Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho, Portugal University of California Berkeley, Estados Unidos
2013/10/01 - 2016/07/20	Establishment of a protocol for the cryopreservation of cell sheets of adipose tissue stem cells Orientador	Ciências Biomédicas (Mestrado) Universidade do Algarve, Portugal Universidade do Minho, Portugal
2009/09/01 - 2015/02/12	Routes to advance vascularized bone tissue engineering constructs Coorientador	Universidade do Minho, Portugal Harvard University Wyss Institute for Biologically Inspired Engineering, Estados Unidos
2007/10/01 - 2013/11/21	Unravel key elements of tissue engineering constructs in the route to skin regeneration Coorientador
2013/01/09 - 2013/11/18	Development of an injectable PHBV microparticles-GG hydrogel hybrid system for tissue engineering applications Orientador	Tecnologia Farmacêutica (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Minho, Portugal
2010/10/01 - 2012/03/07	Identification of the role of pericytes in the vascularization of Tissue Engineering Constructs Coorientador	Genética Comparativa, Molecular e Tecnológica (Mestrado) Universidade de Trás-os-Montes e Alto Douro, Portugal Universidade do Minho, Portugal
2010/09/01 - 2011/12/27	Co-culture of osteogenic and endothelial lineage cells, isolated and differentiated from of SSEA-4 cell fraction from SVF of Human Adipose Tissue Coorientador	Biomedicina Molecular (Mestrado) Universidade de Aveiro, Portugal Universidade do Minho, Portugal
2006/04/01 - 2011/10/23	Co-cultures and cell sheet engineering as relevant tools to improve the outcome of bone tissue engineering strategies Coorientador	Universidade do Minho, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2016 - Atual	European Wound Management Association	Council and Scientific Committee member (from 2016); Executive Committee Member (from 2020); Elected Honorary Secretary
2007 - Atual	Tissue Engineering and Regenerative Medicine International Society
2005 - Atual	Sociedade Portuguesa de Células Estaminais e Terapia Celular	Founder Member; Coordinator of the Section Cell Therapies and Tissue Engineering (2011/2012)
1999 - Atual	European Society for Biomaterials
2017 - 2018	Wound Healing Society
2001 - 2004	Society for Biomaterials
1996 - 1999	Sociedade Portuguesa de Bioquímica