???global.info.a_carregar???
Since 2010, Hugo has worked within the Bacteriophage & Biofilm group of the Centre of Biological Engineering at Uminho, where he got several competitive FCT grants for research positions (PhD 2010-2014, Post-Doc 2015-2021 and Assistant Researcher (currently)). He also took 2 Assistant Professor positions (2014, 2017) and was involved in 6 different courses in 2 MSc courses/1 PhD programme. During his PhD in Chemical and Biological Engineering (2010-2014), he developed antibacterial agents to control bacterial pathogens, by exploiting bacteriophages (phages) and its encoded proteins called endolysins as therapeutic agents. He rotated >1 year in 3 international labs at Institute of Environmental Science and Research (New Zealand), Catholic University of Leuven (Belgium) and Iberian Nanotechnology Laboratory (Portugal) to learn Protein Engineering, NGS and Spectroscopy to identify/characterize these proteins that degrade the cell wall and cause subsequent lysis of bacterial pathogens, resulting in high impact and highly cited papers, 1 international granted patent and 1 license agreement with Lysando AG (Liechtenstein). During his Post-Doc, he focused on the development of antivirulence strategies to control drug-resistant bacterial pathogens, by applying other phage-derived proteins called tailpikes or depolymerases. During this period, he trained in 3 different research centers (CNR - Italy, KU Leuven - Belgium, IST - Portugal), for protein functional analysis, NGS and invertible models to assess bacterial virulence. In parallel, he developed advance genomic screening methods in collaboration with national and international scientists based on python scripts/machine learning techniques, to characterize phage genomes and proteins, building fast scheme tools to identify novel phage proteins with biotechnological potential interest. Moreover, 1 licensing agreement is currently been made with Nemis Technologies (Switzerland). Currently (since 2021) he became an Assistant Researcher at CEB-Uminho. Among other activities, I have been focused on pursuing his new research objectives i.e. “Addressing Antimicrobial Resistance through New Phage-inspired Strategies”, with particular focus in Genetic Engineering, Molecular Biology and Bioinformatics scientific domains. He participated in several national/international scientific projects (11 between 2017-2022 that totalize >3 M€ of competitive funds). As Coordinator, he managed 4 competitive projects: 2 national (FCT - POCI-01-0145-FEDER-029628 - 234 k€; PRR - PRR-C05-i03-I-000179 - 638 K€) and 2 internationals (ESCMID - 20 k€ - approval rate of 20% and Instruct-ERIC - 14 k€ - approval rate of 14%). He was also involved in the preparation of Marie Curie applications (2020) and applied to the ERC Starting grant (2021) where he got a final panel score of B. He is/was involved in the supervision of 1 post-doc fellow, 2 master fellows, 4 PhD students and 10 master students. He has 19 oral presentations in national/international scientific meetings. He co-organized international courses/meetings: Hands-on phage biotechnology in 2015, 2017, 2019, 2023 (25 participants); iVOM Webinars in 2020, 2023 (~1000 unique participants) and co-organized the biggest conference in virology - Viruses of Microbes 2022 (700 participants, ~250 k€ income; link). His current bibliometrics includes 45 peer-reviewed research articles (20 as first and 11 as corresponding/senior author) mostly in Q1 and in Top5 journals (e.g. Env Micr 2017; Jour Virol 2019; App Env Micr 2019; Bionif 2019; Trends Micro 2022) in SJR index, an h-index of 26 and +3000 citations (Google Scholar). He also has 10 scientific distinctions, 1 international granted patent, and 1 license agreement with an international biotechnological company.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
HUGO ALEXANDRE MENDES DE OLIVEIRA

Nomes de citação

  • Oliveira, H.

Identificadores de autor

Ciência ID
D91A-2590-A70C
ORCID iD
0000-0001-9564-5714
Google Scholar ID
DDvpyzMAAAAJ
Scopus Author Id
52464172600

Endereços de correio eletrónico

  • hugooliveira@deb.uminho.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Agrárias - Biotecnologia Agrária e Alimentar - Biotecnologia Agrária e Biotecnologia Alimentar
  • Ciências Médicas e da Saúde - Ciências da Saúde - Doenças Infeciosas

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2010/04 - 2014/03
Concluído
 Chemical and Biological Engineering (Doutoramento)
Universidade do Minho Centro de Engenharia Biológica, Portugal
"Molecular studies on bacteriophage endolysins and their potential to control Gram-negative bacteria" (TESE/DISSERTAÇÃO)
 Approved unanimously
2002/09 - 2008/09
Concluído
 Biological Engineering (Mestrado integrado)
Universidade do Minho Escola de Engenharia, Portugal
"Characterization of bitter beer compounds in different process of beer production and optimization of their laboratory analyses" (TESE/DISSERTAÇÃO)
 15 (ECTS Grading scale, Class A)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021 - Atual Assistente de Investigação (carreira) (Investigação) Universidade do Minho, Portugal
Universidade do Minho Centro de Engenharia Biológica, Portugal
2018/12 - Atual Investigador Contratado (Investigação) Universidade do Minho, Portugal
Universidade do Minho Centro de Engenharia Biológica, Portugal
2014/05 - 2018/11 Pós-doutorado (Investigação) Universidade do Minho, Portugal
Universidade do Minho, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2017 - 2017 Professor Associado Convidado (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho Departamento de Engenharia Biológica, Portugal
2014 - 2015 Professor Associado Convidado (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho Departamento de Engenharia Biológica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2010/04 - 2014/03 PhD student Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho Centro de Engenharia Biológica, Portugal
2014 - 2014 Visiting PhD student International Iberian Nanotechnology Laboratory, Portugal
Universidade do Minho, Portugal
2012 - 2012 Visiting PhD student Katholieke Universiteit Leuven - Campus Kulak Kortrijk, Bélgica
Universidade do Minho Centro de Engenharia Biológica, Portugal
2010 - 2011 Visiting PhD student Institute of Environmental Science and Research (ESR), Nova Zelândia
Universidade do Minho Centro de Engenharia Biológica, Portugal
2009/09 - 2010/03 Quality Engineer Grupo PRIMOR, Portugal
2009/09 - 2009/12 Professional Internship Brauwelt brewery , Alemanha
2007/02 - 2008/09 Erasmus Student Internship Šariš Brewery, Eslováquia
Projetos

Bolsa

Designação Financiadores
2010 - 2014 Molecular studies on bacteriophage endolysins and their potential to control Gram-negative bacteria
SFRH/BD/63734/2009
Bolseiro de Doutoramento
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2023 - 2025 BioFago - New strategies in the control of Fire Blight
PRR-C05-i03-I-000179
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
 IFAP - Instituto de Financiamento de Agricultura e Pescas, IP
2022 - 2024 FITTED - A flexible platform for generating synthetic virus to control infectious diseases
LCF/PR/HP21/52310017
Investigador
Universidade do Minho, Portugal
 ”la Caixa” Foundation
Em curso
2021 - 2024 DeathTrigger - Activating Dormant Bacteria with phage-derived proteins to enhance antibiotic efficacy
PTDC/BIA-MIC/2312/2020
Investigador Pós-doutorado
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021 - 2024 FITTED - A flexible platform for generating synthetic virus to control infectious diseases
HR21-00533
Outra
Fundação "la Caixa"
2021 - 2022 Reprograming bacteriophage tailspikes through structure-guided design
ID:112
Investigador responsável
Universidade do Minho, Portugal
 European Research - Instruct-ERIC
Em curso
2020/04/01 - 2021/09/30 ViBBiP - Viral-Based Bioconjugation Platform for vaccines development against bacterial pathogens
ViBBiP
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
 European Society of Clinical Microbiology and Infectious Diseases
Em curso
2018/09/17 - 2021/09/16 SUSPHAGE - Development of a phage-based product to control Escherichia coli associated post-weaning diarrhoea in piglets
POCI-01-0247-FEDER-033679
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07/26 - 2021/07/25 PhageSTEC - Development of a formulation of encapsulated bacteriophages to reduce enterotoxigenic E. coli in ruminants
POCI-01-0145-FEDER-029628
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07/16 - 2021/07/15 PACKTERIOPHAGE - Bacteriophage-releasing nanostructured smart packaging materials for the control of food-borne campylobacter
POCI-01-0145-FEDER-032594
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07/16 - 2021/07/15 Phages-on-chip - An integrated phage-based microdevice for multiplex detection of bloodstream infections
POCI-01-0145-FEDER-032442
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2012/05 - 2015/08 True-Lyse - Lysin properties adapted to cold temperatures
PTDC/AGR-ALI/121057/2010
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
2013/05 - 2014/12 Lysins G-Force - Development of strategies for the application of phage endolysins to control Gram-negative bacteria
EXPL/BBB-BIO/0907/2012
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a ciência e tecnologia
Concluído
2010/02 - 2013/02 PhageFoodSafe - Development of a phage-based product to control Salmonella and Campylobacter in foodstuffs and food processing surfaces
PTDC/AGR-ALI/100492/2008
Investigador
Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a ciência e tecnologia
Produções

Publicações

Artigo em revista
  1. Castro, Joana; Oliveira, Ricardo; Fernandes, Liliana; Carvalho, Isabel; Oliveira, H.; Brinks, Erik; Cho, Gyu-Sung; et al. "Molecular characterization and virulence profile of Klebsiella pneumoniae and Klebsiella oxytoca isolated from ill cats and dogs in Portugal". Veterinary Microbiology 292 (2024): 110056. http://dx.doi.org/10.1016/j.vetmic.2024.110056.
    Publicado • 10.1016/j.vetmic.2024.110056
  2. Gabriel Abreu; Edgar Garcia; Ana Oliveira; Hugo Oliveira; Kenneth M. Stedman. "Genome sequence of Erwinia amylovora bacteriophage Omen". Microbiology Resource Announcements (2024): https://doi.org/10.1128/mra.00122-24.
    10.1128/mra.00122-24
  3. Akturk, Ergun; Melo, Luís D.R.; Oliveira, Hugo; Crabbé, Aurélie; Coenye, Tom; Azeredo, Joana. "Combining phages and antibiotic to enhance antibiofilm efficacy against an in vitro dual species wound biofilm". Biofilm 6 (2023): 100147. http://dx.doi.org/10.1016/j.bioflm.2023.100147.
    Publicado • 10.1016/j.bioflm.2023.100147
  4. Neto, Sofia; Vieira, Ana; Oliveira, Hugo; Espiña, Begoña. "Assessing Acinetobacter baumannii virulence and treatment with a bacteriophage using zebrafish embryos". The FASEB Journal 37 7 (2023): http://dx.doi.org/10.1096/fj.202300385r.
    Publicado • 10.1096/fj.202300385r
  5. Oliveira, Hugo; Santos, Sílvio; Pires, Diana P.; Boeckaerts, Dimitri; Pinto, Graça; Domingues, Rita; Otero, Jennifer; et al. "CkP1 bacteriophage, a S16-like myovirus that recognizes Citrobacter koseri lipopolysaccharide through its long tail fibers". Applied Microbiology and Biotechnology 107 11 (2023): 3621-3636. http://dx.doi.org/10.1007/s00253-023-12547-8.
    Publicado • 10.1007/s00253-023-12547-8
  6. Gomes, Marta; Domingues, Rita; Turner, Dann; Oliveira, Hugo. "Genomic Analysis of Two Novel Bacteriophages Infecting Acinetobacter beijerinckii and halotolerans Species". Viruses 15 3 (2023): 643. http://dx.doi.org/10.3390/v15030643.
    Publicado • 10.3390/v15030643
  7. Oliveira, Ana; Dias, Carla; Oliveira, Ricardo; Almeida, Carina; Fuciños, Pablo; Sillankorva, Sanna; Oliveira, Hugo. "Paving the way forward: Escherichia coli bacteriophages in a One Health approach". Critical Reviews in Microbiology 50 1 (2023): 87-104. http://dx.doi.org/10.1080/1040841x.2022.2161869.
    Publicado • 10.1080/1040841x.2022.2161869
  8. Ricardo Oliveira; Joana Castro; Sónia Silva; Hugo Oliveira; Maria José Saavedra; Nuno Filipe Azevedo; Carina Almeida. "Exploring the Antibiotic Resistance Profile of Clinical Klebsiella pneumoniae Isolates in Portugal". Antibiotics (2022): https://doi.org/10.3390/antibiotics11111613.
    10.3390/antibiotics11111613
  9. Hanna Fokt; Sara Cleto; Hugo Oliveira; Daniela Araújo; Joana Castro; Nuno Cerca; Maria João Vieira; Carina Almeida. "Bacteriocin Production by Escherichia coli during Biofilm Development". Foods (2022): https://doi.org/10.3390/foods11172652.
    10.3390/foods11172652
  10. Hugo Oliveira; Zuzanna Drulis-Kawa; Joana Azeredo. "Exploiting phage-derived carbohydrate depolymerases for combating infectious diseases". Trends in Microbiology 30 8 (2022): 707-709. https://doi.org/10.1016/j.tim.2022.05.002.
    10.1016/j.tim.2022.05.002
  11. Hugo Oliveira; Rita Domingues; Benjamin Evans; J. Mark Sutton; Evelien M. Adriaenssens; Dann Turner. "Genomic Diversity of Bacteriophages Infecting the Genus Acinetobacter". Viruses (2022): https://doi.org/10.3390/v14020181.
    10.3390/v14020181
  12. L. Blasco; I. Bleriot; M. González de Aledo; L. Fernández-García; O. Pacios; H. Oliveira; M. López; et al. "«Development of an anti- Acinetobacter baumannii biofilm phage cocktail: Genomic Adaptation to the Host»". Antimicrobial Agents and Chemotherapy (2022): https://doi.org/10.1128/AAC.01923-21.
    10.1128/AAC.01923-21
  13. Oliveira, Hugo; Azeredo, Joana. "Treating Bacterial Infections With a Protein From a Virus". Frontiers for Young Minds 9 (2021): http://dx.doi.org/10.3389/frym.2021.648764.
    Publicado • 10.3389/frym.2021.648764
  14. Rita Domingues; Ana Barbosa; Sílvio B. Santos; Diana Priscila Pires; Jonathan Save; Grégory Resch; Joana Azeredo; Hugo Oliveira. "Unpuzzling Friunavirus-Host Interactions One Piece at a Time: Phage Recognizes Acinetobacter pittii via a New K38 Capsule Depolymerase". Antibiotics 10 11 (2021): 1304-1304. https://doi.org/10.3390/antibiotics10111304.
    10.3390/antibiotics10111304
  15. Pinto, Graça; Minnich, Scott A; Hovde, Carolyn J; Oliveira, Hugo; Smidt, Hauke; Almeida, Carina; Azeredo, Joana. "The interactions of bacteriophage Ace and Shiga toxin-producing Escherichia coli during biocontrol". FEMS Microbiology Ecology 97 8 (2021): http://dx.doi.org/10.1093/femsec/fiab105.
    Publicado • 10.1093/femsec/fiab105
  16. Pinto, Graça; Sampaio, Marta; Dias, Oscar; Almeida, Carina; Azeredo, Joana; Oliveira, Hugo. "Insights into the genome architecture and evolution of Shiga toxin encoding bacteriophages of Escherichia coli". BMC Genomics 22 1 (2021): http://dx.doi.org/10.1186/s12864-021-07685-0.
    Publicado • 10.1186/s12864-021-07685-0
  17. Ballem, Andressa; Gonçalves, Soraia; Garcia-Meniño, Isidro; Flament-Simon, Saskia C.; Blanco, Jesús E.; Fernandes, Conceição; Saavedra, Maria José; et al. "Prevalence and serotypes of Shiga toxin-producing Escherichia coli (STEC) in dairy cattle from Northern Portugal". PLOS ONE 15 12 (2020): e0244713. http://dx.doi.org/10.1371/journal.pone.0244713.
    Publicado • 10.1371/journal.pone.0244713
  18. Silva, Maria Daniela; Oliveira, Hugo; Faustino, Alberta; Sillankorva, Sanna. "Characterization of MSlys, the endolysin of Streptococcus pneumoniae phage MS1". Biotechnology Reports (2020): e00547. http://dx.doi.org/10.1016/j.btre.2020.e00547.
    Publicado • 10.1016/j.btre.2020.e00547
  19. Fiedler, Gregor; Ballem, Andressa; Brinks, Erik; Almeida, Carina; Franz, Charles M. A. P.; Oliveira, Hugo. "Draft Genome Sequences of 12 Shiga Toxin-Producing Escherichia coli Strains Isolated from Dairy Cattle in Portugal". Microbiology Resource Announcements 9 38 (2020): http://dx.doi.org/10.1128/mra.00790-20.
    10.1128/mra.00790-20
  20. Ferreira, Alice; Oliveira, Hugo; Silva, Daniela; Almeida, Carina; Burgan, Julia; Azeredo, Joana; Oliveira, Ana. "Complete Genome Sequences of Eight Phages Infecting Enterotoxigenic Escherichia coli in Swine". Microbiology Resource Announcements 9 36 (2020): http://dx.doi.org/10.1128/mra.00858-20.
    Publicado • 10.1128/mra.00858-20
  21. Dias, Carla; Almeida, Carina; Lobocka, Malgorzata; Oliveira, Hugo. "Genome Sequences of Four Potentially Therapeutic Bacteriophages Infecting Shiga Toxin-Producing Escherichia coli". Microbiology Resource Announcements 9 36 (2020): http://dx.doi.org/10.1128/mra.00749-20.
    Publicado • 10.1128/mra.00749-20
  22. Oliveira, Hugo; Pinto, Graça; Mendes, Bruna; Dias, Oscar; Hendrix, Hanne; Akturk, Ergun; Noben, Jean-Paul; et al. "Tailspike with EPS-depolymerase activity, encoded by a phage belonging to a new genus, makes Providencia stuartii susceptible to serum-mediated killing". Applied and Environmental Microbiology (2020): http://dx.doi.org/10.1128/aem.00073-20.
    Aceite para publicação • 10.1128/aem.00073-20
  23. Oliveira, Hugo; Melo, Luís D. R.; Pires, Diana P.; Dabrowska, Krystyna; Azeredo, Joana. "Phage therapy efficacy: a review of the last 10 years of preclinical studies". Critical Reviews in Microbiology (2020): 1-22. http://dx.doi.org/10.1080/1040841x.2020.1729695.
    Publicado • 10.1080/1040841x.2020.1729695
  24. Hugo Oliveira; Marta Sampaio; Luís D. R. Melo; Oscar Dias; Welkin H. Pope; Graham F. Hatfull; Joana Azeredo. "Staphylococci phages display vast genomic diversity and evolutionary relationships". BMC Genomics 20 1 (2019): https://doi.org/10.1186/s12864-019-5647-8.
    Publicado • 10.1186/s12864-019-5647-8
  25. Ribeiro, Henrique G.; Melo, Luís D. R.; Oliveira, Hugo; Boon, Maarten; Lavigne, Rob; Noben, Jean-Paul; Azeredo, Joana; Oliveira, Ana. "Characterization of a new podovirus infecting Paenibacillus larvae". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-56699-y.
    Publicado • 10.1038/s41598-019-56699-y
  26. Luís D. R. Melo; R. Ferreira; Ana R. Costa; H. Oliveira; J. Azeredo. "Efficacy and safety assessment of two enterococci phages in an in vitro biofilm wound model". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-019-43115-8.
    Publicado • 10.1038/s41598-019-43115-8
  27. Milho, Catarina; Silva, Maria Daniela; Alves, Diana; Oliveira, Hugo; Sousa, Clara; Pastrana, Lorenzo M.; Azeredo, Joana; Sillankorva, Sanna. "Escherichia coli and Salmonella Enteritidis dual-species biofilms: interspecies interactions and antibiofilm efficacy of phages". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-54847-y.
    Publicado • 10.1038/s41598-019-54847-y
  28. Fraga, Alexandra G.; Trigo, Gabriela; Murthy, Ramya K.; Akhtar, Shamim; Hebbur, Madhavi; Pacheco, Ana Rita; Dominguez, Juan; et al. "Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection". PLOS Neglected Tropical Diseases 13 8 (2019): e0007113. http://dx.doi.org/10.1371/journal.pntd.0007113.
    Publicado • 10.1371/journal.pntd.0007113
  29. Sampaio, Marta; Rocha, Miguel; Oliveira, Hugo; Dias, Oscar. "Predicting promoters in phage genomes using PhagePromoter". Bioinformatics 35 24 (2019): 5301-5302. http://dx.doi.org/10.1093/bioinformatics/btz580.
    Publicado • 10.1093/bioinformatics/btz580
  30. Akturk, Ergun; Oliveira, Hugo; Santos, Sílvio B.; Costa, Susana; Kuyumcu, Suleyman; Melo, Luís D. R.; Azeredo, Joana. "Synergistic Action of Phage and Antibiotics: Parameters to Enhance the Killing Efficacy Against Mono and Dual-Species Biofilms". Antibiotics 8 3 (2019): 103. http://dx.doi.org/10.3390/antibiotics8030103.
    Publicado • 10.3390/antibiotics8030103
  31. Oliveira, H.; Mendes, A.; Fraga, A.G.; Ferreira, A.; Pimenta, A.I.; Mil-Homens, D.; Fialho, A.M.; Pedrosa, J.; Azeredo, J.. "K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis". Applied and environmental microbiology 85 17 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071352666&partnerID=MN8TOARS.
    Publicado • 10.1128/AEM.00934-19
  32. Oliveira, H.; Costa, A.R.; Ferreira, A.; Konstantinides, N.; Santos, S.B.; Boon, M.; Noben, J.-P.; Lavigne, R.; Azeredo, J.. "Functional analysis and antivirulence properties of a new depolymerase from a myovirus that infects acinetobacter baumannii capsule K45". Journal of Virology 93 4 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85061125005&partnerID=MN8TOARS.
    Publicado • 10.1128/JVI.01163-18
  33. Oliveira, Hugo; São-José, Carlos; Azeredo, Joana. "Phage-Derived Peptidoglycan Degrading Enzymes: Challenges and Future Prospects for In Vivo Therapy". Viruses 10 6 (2018): 292. http://dx.doi.org/10.3390/v10060292.
    Publicado • 10.3390/v10060292
  34. Oliveira, Hugo; Costa, Ana R.; Konstantinides, Nico; Ferreira, Alice; Akturk, Ergun; Sillankorva, Sanna; Nemec, Alexandr; et al. "Ability of phages to infectAcinetobacter calcoaceticus-Acinetobacter baumanniicomplex species through acquisition of different pectate lyase depolymerase domains". Environmental Microbiology 19 12 (2017): 5060-5077. http://dx.doi.org/10.1111/1462-2920.13970.
    Publicado • 10.1111/1462-2920.13970
  35. Endersen, Lorraine; Buttimer, Colin; Nevin, Eoghan; Coffey, Aidan; Neve, Horst; Oliveira, Hugo; Lavigne, Rob; O'Mahony, Jim. "Investigating the biocontrol and anti-biofilm potential of a three phage cocktail against Cronobacter sakazakii in different brands of infant formula". International Journal of Food Microbiology 253 (2017): 1-11. http://dx.doi.org/10.1016/j.ijfoodmicro.2017.04.009.
    Publicado • 10.1016/j.ijfoodmicro.2017.04.009
  36. Oliveira, Hugo; Pinto, Graça; Oliveira, Ana; Noben, Jean-Paul; Hendrix, Hanne; Lavigne, Rob; Lobocka, Malgorzata; Kropinski, Andrew M.; Azeredo, Joana. "Characterization and genomic analyses of two newly isolated Morganella phages define distant members among Tevenvirinae and Autographivirinae subfamilies". Scientific Reports 7 1 (2017): http://dx.doi.org/10.1038/srep46157.
    Publicado • 10.1038/srep46157
  37. Oliveira, H.; Pinto, G.; Hendrix, H.; Noben, J.-P.; Gawor, J.; Kropinski, A.M.; Lobocka, M.; Lavigne, R.; Azeredo, J.. "A lytic Providencia rettgeri virus of potential therapeutic value is a deepbranching member of the T5virus genus". Applied and Environmental Microbiology 83 23 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85034062121&partnerID=MN8TOARS.
    Publicado • 10.1128/AEM.01567-17
  38. Buttimer, C.; Hendrix, H.; Oliveira, H.; Casey, A.; Neve, H.; McAuliffe, O.; Paul Ross, R.; et al. "Things are getting hairy: Enterobacteria bacteriophage vB_PcaM_CBB". Frontiers in Microbiology 8 JAN (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85011961519&partnerID=MN8TOARS.
    Publicado • 10.3389/fmicb.2017.00044
  39. Ferreira, Carina; Gonçalves, Bruna; Vilas Boas, Diana; Oliveira, Hugo; Henriques, Mariana; Azeredo, Joana; Silva, Sónia. "Candida tropicalisbiofilm and human epithelium invasion is highly influenced by environmental pH". Pathogens and Disease 74 8 (2016): ftw101. http://dx.doi.org/10.1093/femspd/ftw101.
    Publicado • 10.1093/femspd/ftw101
  40. Oliveira, H.; Pinto, G.; Oliveira, A.; Oliveira, C.; Faustino, M.A.; Briers, Y.; Domingues, L.; Azeredo, J.. "Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates". Applied Microbiology and Biotechnology 100 24 (2016): 10543-10553. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988927829&partnerID=MN8TOARS.
    Publicado • 10.1007/s00253-016-7858-0
  41. Oliveira, H.; Boas, D.V.; Mesnage, S.; Kluskens, L.D.; Lavigne, R.; Sillankorva, S.; Secundo, F.; Azeredo, J.. "Structural and enzymatic characterization of ABgp46, a novel phage endolysin with broad anti-gram-negative bacterial activity". Frontiers in Microbiology 7 FEB (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84962129551&partnerID=MN8TOARS.
    Publicado • 10.3389/fmicb.2016.00208
  42. Pires, D.P.; Oliveira, H.; Melo, L.D.R.; Sillankorva, S.; Azeredo, J.. "Bacteriophage-encoded depolymerases: their diversity and biotechnological applications". Applied Microbiology and Biotechnology 100 5 (2016): 2141-2151. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954421775&partnerID=MN8TOARS.
    Publicado • 10.1007/s00253-015-7247-0
  43. Oliveira, Hugo; Sillankorva, Sanna; Merabishvili, Maia; Kluskens, Leon D.; Azeredo, Joana. "Unexploited opportunities for phage therapy". Frontiers in Pharmacology 6 (2015): http://dx.doi.org/10.3389/fphar.2015.00180.
    Publicado • 10.3389/fphar.2015.00180
  44. Oliveira, Hugo; Thiagarajan, Viruthachalam; Walmagh, Maarten; Sillankorva, Sanna; Lavigne, Rob; Neves-Petersen, Maria Teresa; Kluskens, Leon D.; Azeredo, Joana. "A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids". PLoS ONE 9 10 (2014): e108376. http://dx.doi.org/10.1371/journal.pone.0108376.
    Publicado • 10.1371/journal.pone.0108376
  45. Briers, Yves; Walmagh, Maarten; Van Puyenbroeck, Victor; Cornelissen, Anneleen; Cenens, William; Aertsen, Abram; Oliveira, Hugo; et al. "Engineered Endolysin-Based “Artilysins” To Combat Multidrug-Resistant Gram-Negative Pathogens". mBio 5 4 (2014): http://dx.doi.org/10.1128/mbio.01379-14.
    Publicado • 10.1128/mbio.01379-14
  46. Oliveira, H.; Melo, L. D. R.; Santos, S. B.; Nobrega, F. L.; Ferreira, E. C.; Cerca, N.; Azeredo, J.; Kluskens, L. D.. "Molecular Aspects and Comparative Genomics of Bacteriophage Endolysins". Journal of Virology 87 8 (2013): 4558-4570. http://dx.doi.org/10.1128/jvi.03277-12.
    Publicado • 10.1128/jvi.03277-12
  47. Oliveira, Hugo; Azeredo, Joana; Lavigne, Rob; Kluskens, Leon. D.. "Bacteriophage endolysins as a response to emerging foodborne pathogens". Trends in Food Science & Technology 28 2 (2012): 103-115. http://dx.doi.org/10.1016/j.tifs.2012.06.016.
    Publicado • 10.1016/j.tifs.2012.06.016
  48. Oliveira, Hugo; Sillankorva, Sanna M.; Azeredo, Joana. "Bacteriophages and Their Role in Food Safety". International Journal of Microbiology 2012 (2012): 1-13. http://dx.doi.org/10.1155/2012/863945.
    Publicado • 10.1155/2012/863945
  49. Sillankorva, Sanna; Pires, Diana; Oliveira, Hugo; Neubauer, Peter; Azeredo, Joana. "The Influence of P. fluorescens Cell Morphology on the Lytic Performance and Production of Phage ¿IBB-PF7A". Current Microbiology 63 4 (2011): 347-353. http://dx.doi.org/10.1007/s00284-011-9987-0.
    Publicado • 10.1007/s00284-011-9987-0
Artigo em revista (magazine)
  1. "Bacteriófagos: Novos agentes antibacterianos para controlo alimentar", TecnoAlimentar, 2021, http://www.tecnoalimentar.pt/noticias/bacteriofagos-novos-agentes-antibacterianos-para-controlo-alimentar/.
Capítulo de livro
  1. Santos, Sílvio B.; Melo, Luís D.R.; Oliveira, Hugo. "Phage Structural Antimicrobial Proteins". In Bacterial Viruses: Exploitation for Biocontrol and Therapeutics. Irlanda: Caister Academic Press, 2020.
    Publicado • 10.21775/9781913652517.12
  2. Oliveira, H; Melo, L.D.R.; Santos, Sílvio B.. "Bacteriophage Proteins as Antimicrobials to Combat Antibiotic Resistance". In Antibiotic Drug Resistance, editado por Muthyala, R.; Martinez, JLC.; Igrejas, G.; Sham, Y.. John Wiley & Sons, Inc., 2019.
    Publicado
  3. Sampaio, Marta; Rocha, Miguel; Oliveira, Hugo; Dias, Oscar. "Predicting Promoters in Phage Genomes Using Machine Learning Models". In Practical Applications of Computational Biology and Bioinformatics, 13th International Conference, 105-112. Springer International Publishing, 2019.
    Publicado • 10.1007/978-3-030-23873-5_13
  4. Melo, L.D.R.; Oliveira, H.; Santos, Sílvio B.; Sillankorva, S.; Azeredo, J.. "Phages Against Infectious Diseases". In Bioprospecting - Success, Potential and Constraints, editado por Paterson, Russell; Lima, Nelson, 269-294. Springer International Publishing, 2017.
    Publicado
Poster em conferência
  1. Domingues R; Oliveira H; Azeredo J. "Engineering therapeutic bacteriophages against A. baumannii by adjusting phage specificity to cover a large range of capsular types". Trabalho apresentado em 33rd European Congress of Clinical Microbiology & Infectious Disease (ECCMID), 2023.
  2. Vieira M; Duarte J; Dias O; Rocha M; Azeredo J; Oliveira, H. "Development of comprehensive methodologies for bacteriophage-host studies". Trabalho apresentado em Bioinformatics Open Days 2023, 2023.
  3. Oliveira, H. "Development of comprehensive methodologies for bacteriophage-host studies". Trabalho apresentado em Bioinformatics Open Days 2023, 2023.
  4. Oliveira, H. "Characterization of Acinetobacter baumannii phage vB_Ab-P-7". Trabalho apresentado em Virus of Microbes, 2023.
  5. Oliveira, H. "Advances in the diversity of Acinetobacter phage-encoded capsular depolymerases". Trabalho apresentado em Virus of Microbes, 2023.
  6. "Studies on the interaction of T4-like phages and diarrheagenic Escherichia coli strains". Trabalho apresentado em FEMS22, 2022.
  7. "PhageDPO: Phage Depolymerase Finder". Trabalho apresentado em XI Bioinformatics Open Days, 2022.
  8. Monteiro R; Melo R; Domingues R; Oliveira, H; Maarten J; Azeredo J. "The Acinetobacter baumannii SOS gene ddrR is crucial for prophage maintenance and induction". Trabalho apresentado em Virus of Microbes 2022, 2022.
  9. Domingues R; Oliveira R; Almeida C; Cho GS; Franz C; Resch G; Azeredo J; Oliveira, H. "Building a collection of phage-derived capsular depolymerases to tackle relevant A. baumannii capsular types". Trabalho apresentado em Virus of Microbes 2022, 2022.
  10. Oliveira, H.. "Adaptation of a lytic mutant phage for the generation of an antibiofilm phage cocktail with potential use in phage therapy". Trabalho apresentado em ECCMID 2021, 2021.
  11. "Bacteriophages to tackle swine colibacillosis: assessing the potential of this alternative therapy". Trabalho apresentado em World Microbe Forum, 2021.
  12. Oliveira, H.. "Safety assessment of the biocontrol of Shiga toxin-producing Escherichia coli using bacteriophages". Trabalho apresentado em Phage Futures Congress, 2021.
  13. Pacio, O.; Blasco, L.; Bleriot, I.; Fernandez-Garcia, L.; Bardanca1, M.G.; Ambroa, A.; López, M.; et al. "Activity of an engineered-phage in combination with natural lytic phages against clinical strains of A. baumannii". Trabalho apresentado em American Society of Microbiology (ASM) Microbe 2020, 2020.
  14. Oliveira, H; Balem, A.; Gonçalves, S.; Garcia-Meniño, I; Flament-Simon, S.C.; Blanco, J.E.; Pinto, J.; et al. "Prevalence and Genetic Characterization of Shiga Toxin-Producing Escherichia coli (STEC) Isolates from cattle in Portugal". Trabalho apresentado em 30th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
  15. Ballem A.; Gonçalves, S.; Ferreira A. I.; Fernandes C.; Saavedra M. J.; Pinto C.; Oliveira, H; Almeida G.; Almeida, C.. "Prevalence of shigatoxigenic escherichia coli in bovine cattle: a survey in the north region of portugal". Trabalho apresentado em SAlimentar 2019 - 1º Simpósio INIAV para a Segurança Alimentar (Rumo à Alimentação do Futuro), 2019.
  16. Gonçalves, Soraia; Ferreira, Isabel; Guedes, Hugo; Oliveira, H; Almeida, Carina; Afonso, Isabel; Almeida, Gonçalo. "Perfil de resistência a antibióticos de escherichia coli produtoras e não produtoras da toxina shiga". Trabalho apresentado em SAlimentar 2019 - 1º Simpósio INIAV para a Segurança Alimentar (Rumo à Alimentação do Futuro), 2019.
  17. Ribeiro, Henrique G; Melo, Luís D. R.; Oliveira, H.; Boon, Maarten; Lavigne, Rob; Azeredo, Joana; Oliveira, A.. "API480: features towards therapy in honeybee hives". Trabalho apresentado em 23rd Biennial Evergreen International Phage Meeting, 2019.
  18. Sampaio, M.; Rocha, M.; Oliveira, H; Dias, O.. "Predicting promoters in phage genomes using PhagePromoter". Trabalho apresentado em Bioinformatics Open Days, 2019.
  19. Akturk, E.; Oliveira, H.; Sílvio B. Santos; Melo, L.D.R.; Azeredo, J.. "Interaction of Phage and Gentamicin Combinations in Pseudomonas aeruginosa and Staphylococcus aureus Polymicrobial Biofilms23rd Biennial Evergreen International Phage Meeting". Trabalho apresentado em 23rd Biennial Evergreen International Phage Meeting, 2019.
  20. Oliveira, H; Costa, A.R.; Ferreira, A.; Mil-Homens, D.; Fialho, A.M.; Azeredo, J.. "Anti-virulent properties of a phage-encoded depolymerase against A. baumannii K2 capsular type". Trabalho apresentado em Viruses of Microbes, 2018.
  21. Oliveira, H; Akturk, E.; Melo, L.D.R.; Azeredo, J.. "Synergetic efect between phage and antibiotics as an alternative strategy to control Pseudomonas aeruginosa biofilm associated infections". Trabalho apresentado em Viruses of Microbes 2018, 2018.
  22. Oliveira, H; Akturk, E.; Melo, L.D.R.; Azeredo, J.. "Combined treatment with bacteriophages and antibiotics as a strategy to control biofilm associated infections". Trabalho apresentado em Microbiotec'17 - Congress of Microbiology and Biotechnology 2017, 2017.
  23. Buttimer, C.; Oliveira, H; Hendrix, H.; Lavigne, R.; Neve, H.; McAuliffe, O.; Hill, C.; O’Mahony, J.; Coffey, A.. "Characterization of the Enterobacteria 'jumbo' bacteriophage vb_Pcam_CBB". Trabalho apresentado em International Union of Microbiological Societes, 2017.
  24. Buttimer, C; Hendrix, H; Oliveira, H; Lavigne, R; Neves, R.; McAuliffe, O; Hill, C; O’Mahony, J; Coffey, A. "Characterization of the Enterobacteria 'jumbo' bacteriophage VB_Pcam_CBB". Trabalho apresentado em IMUS 2017 - 15th International Congress of Bacteriology and Applied Microbiology, 15th International Congress of Mycology and Eukaryotic Microbiology and 17th International Congress of Virology, 2017.
  25. Santos, Sílvio B.; Brandão, A.; Oliveira, A.; Melo, L.D.R.; Pinto, G.; Oliveira, H; Ferreira, E.; Azeredo, J.. "New Bacterial Biorecognition Elements from Phage Origin". Trabalho apresentado em CEB Scientific Annual Meeting, 2017.
    10.29173/ikc3217
  26. Graça, P.; Oliveira, H; Oliveira, A.; Azeredo, J.. "Characterization of novel broad-spectra Citrobacter freundii infecting bacteriophage". Trabalho apresentado em Evergreen International Phage Biology Meeting, 2017.
  27. Buttimer, C.; Oliveira, H; Hendrix, H.; Lavigne, R.; Neve, H.; McAuliffe, O.; Hill, C.; O’Mahony, J.; Coffey, A.. "Analysis of the atypical ‘hairy’ Enterobacteriacea phage vB_PcaM_CBB". Trabalho apresentado em Viruses of Microbes, 2016.
  28. Oliveira, H; Pires, D.; Melo, L.D.R.; Kluskens, L.D.; Sillankorva, S.; Azeredo, J.. "Bacteriophage depolymerases: novel polysaccharide degrading enzymes". Trabalho apresentado em Biofilms, 2016.
  29. Briers, Y.; Walmagh, M.; Puyenbroeck, V.V.; Cornelissen, A.; Cenens, W.; Aertsen, A.; Oliveira, H; et al. "Polycationic, endolysin-based ´Artlysins´ to combact multidrug resistant Gram-negative pathogens". Trabalho apresentado em Viruses of Microbes, 2014.
  30. Oliveira, H; Thiagarajan, V.; Walmagh, M.; Sillankorva, S.; Secundo, F.; Lavigne, R.; Neves-Petersen, M.T.; Kluskens, L.D.; Azeredo, J.. "Biochemical characterization of highly stable endolysins with a powerful and broad anti-Gram-negative lytic activity in the presence of weak acids". Trabalho apresentado em Viruses of Microbes, 2014.
  31. Trigo, G.; Martins, T.G.; Oliveira, H; Fraga, A.G.; Castro A.G.; Azeredo, J.; Pedrosa, J.. "Innovative anti-microbial strategies against Buruli ulcer: Bacteriophage Therapy". Trabalho apresentado em MicroBiotec - Congress of Microbiology and Biotechnology, 2013.
  32. Nóbrega, F.L.; Oliveira, H.; Melo, L.D.R.; Santos, Sílvio B.; Cerca, N.; Ferreira, E.C.; Azeredo, J.. "Insights into phage endolysins". Trabalho apresentado em Bioinformatics Open Days, 2013.
  33. Oliveira, H; Melo, L.D.R.; Nóbrega, F.L.; Santos, Sílvio B.; Cerca, N.; Ferreira, E.C.; Azeredo, J.. "Unraveling the insights into phage endolysin association". Trabalho apresentado em Viruses of Microbes, 2012.
  34. Oliveira, H; Carvalho, CM; Santos, SB; Kluskens, LD; Azeredo, J. "Exploiting the biotechnological potential of bacteriophages towards food safety". Trabalho apresentado em 3rd Meeting of the Institute for Biotechnology and Bioengineering, 2012.
  35. Oliveira, H; Walmagh, M.; Kluskens, L.D.; Sillankorva, S.; Lavigne, R.; Azeredo, J.. "Antibacterial activity on opportunistic Pseudomonas aeruginosa pathogen by a novel Salmonella phage endolysin". Trabalho apresentado em MicroBiotec - Congress of Microbiology and Biotechnology, 2011.
  36. Oliveira, H; Walmagh, M.; Kluskens, L.D.; Sillankorva, S.; Lavigne, Rob; Azeredo, J.. "Biochemical and antibacterial characterization of a novel phage endolysin against the Gram-negative pathogen Pseudomonas aeruginosa". Trabalho apresentado em Evergreen International Phage Biology Meeting, 2011.
  37. Kluskens, Leon; Santos, Sílvio B.; Fernandes, Elisabete Ramos; Oliveira, H.; Melo, Luís D. R.; Cerca, Nuno; Sillankorva, Sanna; Azeredo, Joana. "The use of bacteriophage endolysins as antibacterial compounds". Trabalho apresentado em CEB anual meeting, 2010.
Pré-impressão
  1. Vieira, Maria; Duarte, José; Domingues, Rita; Oliveira, H; Dias, Oscar. "PhageDPO: Phage Depolymerase Finder". 2023. http://dx.doi.org/10.1101/2023.02.24.529883.
    10.1101/2023.02.24.529883
Relatório
  1. Oliveira, H.. 2018. Create one new genus, Priunavirus, containing one new species, in the family Siphoviridae, order Caudovirales 2018. https://talk.ictvonline.org/ictv/proposals/2018.128B.A.v1.Priunasvirus.zip.
Website
  1. Oliveira, H. Microsummit. 2022. www.microsummit-2022.com.

Artística / Interpretação

Gravação vídeo
  1. Oliveira, H; TecMinho (Produtor). 2018. Novel antimicrobial therapy with phage derived depolymerases.
  2. Oliveira, H; Centre of Biological Enginnering (Produtor). 2017. Explorando o potencial dos vírus para o tratamento de infeções bacterianas.
  3. Oliveira, H; Tecminho (Produtor). 2013. MAGniPHI combate infeções.
Interpretação artística
  1. 2023. Podcast “Os Microbiólogos” creation.

Propriedade Intelectual

Patente
  1. Oliveira, H.; Azeredo, J.. 2018. "Novel endolysin (international patent)".
    Concedida/Emitida

Outros

Outra produção
  1. Special issue. Oliveira, Ana. 2019. Special issue: Bacteriophage Ecology and Evolution. Guest Editor of Virology Journal.. 2019. Oliveira, H. https://www.biomedcentral.com/collections/bacteriophageecoevo.
  2. Online tool. PhagePromoter detects promoters in phage genomes.. 2019. Oliveira, H. https://bit.ly/2Dfebfv..
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024 Advancements in bacteriophage-based therapies to control multidrug resistant infections 13th Congress of the Serbian Society for Microbiology
(Belgrade , Sérvia)
2023 Genetic manipulation of A. baumannii-infecting bacteriophages to tackle a larger range of capsular types 13th International Symposium on the Biology of Acinetobacter
(Coimbra, Portugal)
2023 Engineering Phages to Target Different Bacterial Capsule Serotypes IV Encontro Internacional da Sociedade Portuguesa de Genética
(Braga, Portugal)
2023 Machine Learning in the Service of Phage Analysis: Advancements, Applications, Future Prospects Phages Hands on International Course
2023 The use of bacteriophages to reduce antibiotic-resistant pathogens 2th Egas Moniz One Health Symposium
(Lisbon, Portugal)
2022 Disclosing the full diversity of A. baumannii bacteriophage capsular depolymerases AcinetoVibes
2022 Understanding the complete reservoir of bacteriophage depolymerases against A. baumannii capsules Viruses of Microbes
(Guimarães, Portugal)
2022 Proteínas imunogénicas contra A. baumannii: recurso para combater multirresistência
2021/11/23 Prevalence and control of Shiga toxin-producing E. coli: from diversity in dairy cattle to phage therapy Microbiotec 2021
(Portugal)
2021/08/04 CkP1 is a novel S16-like broad-host-range myovirus that recognizes Citrobacter koseri lipopolysaccharide through its long tail fibres 24th Biennial Evergreen Phage Meeting
Evergreen State College (Evergreen, Seattle, Estados Unidos)
2021/06 Reprograming bacteriophage tailspikes through structure-guided design Portuguese Centre for Integrated Structural Biology webinar
Universidade NOVA de Lisboa (Lisbon, Portugal)
2021/06 Phage Capsular Depolymerases World Microbe Forum
American Society of Microbiology (ASM) and the Federation of European Microbiological Societies (FEMS)
2021 Encapsulated bacteriophages for pre-slaughter interventions to reduce Shiga toxin-producing E. coli (STEC) in ruminants VIII jornadas Internacionais de Bovinicultura
2021 Phage Capsular Depolymerases, from exploration to exploitation Word Microbe Forum
2021 Bacteriophage tailspikes through structure-guided design Instruct-Eric webinar
2020/09/10 Long tail fibers of CkP1, a S16-like phage, exhibit broad binding spectrum against Citrobacter koseri Oxford Bacteriophage Conference – Phages 2020
Oxford University (Oxford, Reino Unido)
2020/02/05 Bacteriophage depolymerases: evolutionary insights and antivirulence strategies against bacterial pathogens Viruses 2020 - Novel Concepts in Virology
(Barcelona, Espanha)
2019/12/06 Novel capsular depolymerases-based strategy to kill multidrug-resistant pathogenic bacteria Microbiotec'19 - Congress of Microbiology and Biotechnology 2019
University of Coimbra (Coimbra, Portugal)
2019/09/11 Bacteriophage-depolymerases: their diversity and therapeutic properties Oxford Bacteriophage Conference – Phages
University of Leicester (Oxford, Reino Unido)
2018/11/08 Endolysin binding domain is highly conserved in staphylococcal phage genomes International symposoium on Antimicrobial hydrolytic enzymes
Rockefeller university (New york, Estados Unidos)
2018/11/08 Bacteriophages lysins to detect and control pathogens: two case studies The 2nd International Symposium on Antimicrobial Hydrolytic Enzymes
Rockefeller University (New York, Estados Unidos)
2018/07/09 Novel antimicrobial therapy with phage derived depolymerases iTeams
PhD MIT program (Lisbon, Portugal)
2018/07/03 Bacteriophage polysaccharide depolymerases, their role and biotechnological applications Viruses of Microbes 2018
University of Wroclaw (Wroclaw, Polónia)
2017/11/23 Explorando o potencial dos vírus para o tratamento de infeções bacterianas CEB Talk
Startup Braga (Braga, Portugal)
2017/07/06 Bacteriophage-derived enzymes: from exploration to exploitation CEB Scientific Annual Meeting
University of Minho (Braga, Portugal)
2016/10/13 Capsule depolymerase activity of phages infecting the Acinetobacter baumannii-calcoaceticus complex International Scientific Conference. Bacteriophages: Theoretical and Practical Aspects of Their Application in Medicine
Marins Park Hotel (Moscow, Rússia)
2014/07/05 Development of Bacteriophage Endolysins to Control Gram-negative Pathogens Symposium
Istituto di Chimica del Riconoscimento Molecolare (Milan, Itália)
2013/10/02 Molecular and functional aspects of bacteriophage endolysins BioMicroWorld – International Conference on Environmental, Industrial and Applied Microbiology
Faculty of Medicine - Complutense University (Madrid, Espanha)
2012/03/01 Insights into phage endolysins Bioinformatics Open Days
University of Minho (Braga, Portugal)
2010/10/27 The use of bacteriophage endolysins as antibacterial compounds 2nd Meeting of the Institute for Biotechnology and Bioengineering
Uniservidade do Minho (Braga, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024 - 2034 Isolation of broad-host range phages targeting Acinetobacter/Klebsiella
Orientador
 Biological Engineering (Mestrado)
Universidade do Minho, Portugal
2023 - 2024 Isolation of bacteriophages targeting E. amylovora phytopathogen isolates
Orientador
 Applied Biochemistry (Mestrado)
Universidade do Minho, Portugal
2023 - 2024 ErwiniaTyping - Genotyping tool for Erwinia amylovora capsules
Orientador
 Bioinformatics (Mestrado)
Universidade do Minho, Portugal
2021/01/01 - 2023/12/31 A flexible platform for generating Acinetobacter synthetic phages to control infectious diseases
Coorientador
 Chemical and Biologiocal Enginnering (Outra)
2022 - 2023 PhageAnnotate: Viral Genome Classifier
Orientador
 Bioinformatics (Mestrado)
Universidade do Minho, Portugal
2022 - 2023 New Vector for Controlled Gene Expression in Acinetobacter baumannii
Orientador
 Biotechnology (Mestrado)
Universidade do Minho, Portugal
2021/09 - 2022/07 Assessing a novel anti-virulence therapy against drug-resistant bacterial infections using the Zebrafish in vivo model
Orientador
 Biomedical Engineering (Mestrado)
Universidade do Minho, Portugal
2021/09 - 2022/07 Isolation of novel immunogenic protein carriers for vaccine development
Orientador
 Biotechnology (Mestrado)
Universidade do Minho, Portugal
2021 - 2022 Characterization of novel Acinetobacter baumannii phage-derived depolymerases with anti-virulence properties
Orientador
 Biotechnology (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2021 - 2022 PhageDPO: Phage Depolymerase Finder
Orientador
 Computer science (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2021 - 2021 Instruct project
Orientador
 Master researcher (Outra)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2018 - 2021 PhageSTEC project
Orientador
 Postdoctoral Reseracher (Outra)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2019 - 2020 Bacteriophage-host determinants: identification of bacteriophage receptors through machine learning techniques
Coorientador de Pedro Henrique Matela Aidos Manso de Araújo
 Bioinformatics (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2019 - 2020 Microencapsulation of bacteriophages against food pathogens for oral administration to ruminants
Orientador
 Biotechnology (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2019 - 2019 Phage-based depolymerases as antibiotics
Orientador
 Applied Biology (Licenciatura/Bacharelato)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2017 - 2018 PhagePromoter: Phage Promoters Online Analysis Tool
Coorientador de Marta Sofia Costa Sampaio
 Bioinformatics (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2017 - 2018 Otopathogens: characterization and alternative treatments
Orientador
 Biomedical Engineering (Mestrado)
Universidade do Minho, Portugal
2016 - 2017 Targeting acinetobacter baumannii infectious biofilms with a multivalent phage and bacteria based enzyme cocktail
Orientador de Alice Maria Fernandes Ferreira
 Biotechnology (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2016 - 2017 Genomic comparisons of novel Providencia infecting bacteriophages
Orientador
 Computer science (Mestrado)
Universidade do Minho Centro de Engenharia Biológica, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023 - 2024 iVoM2023 (iVOM3) webinar (2023 - 2024)
Encontro (Coorganizador)
 Universidade do Minho, Portugal
2020/09 - 2021/03 iVoM2020 and the title Viruses of Microbes 2020 webinar series: take a walk on the VoM side (2020/09 - 2021/03)
Seminário (Coorganizador)
 Universidade do Minho Centro de Engenharia Biológica, Portugal
2020/07/13 - 2020/07/17 Organizer of Virus of Microbes 2020 (2020/07/13 - 2020/07/17)
Conferência (Coorganizador)
 Universidade do Minho, Portugal
2017/06/19 - 2017/06/23 Organiser of the 3rd International hands-on phage biotechnology course (HOP III) (2017/06/19 - 2017/06/23)
Oficina (workshop) (Coorganizador)
 Universidade do Minho, Portugal
2015/06/15 - 2015/06/19 Organiser of the 2nd International hands-on phage biotechnology course (HOP II) (2015/06/15 - 2015/06/19)
Oficina (workshop) (Coorganizador)
 Universidade do Minho, Portugal
2013/07/01 - 2013/07/04 Organiser of the 1st International hands-on phage biotechnology course (HOP I) (2013/07/01 - 2013/07/04)
Oficina (workshop) (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2009/05/09 - 2009/05/13 3rd International Practical Course on Biofilm Sciences (2009/05/09 - 2009/05/13)
Oficina (workshop) (Coorganizador)
 Universidade do Minho, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022/05/18 - 2022/05/20 Participant
Conferência
 London Calling 2022
Oxford Nanopore Technologies Plc, Reino Unido
2022 - 2022 Microsummit 2022
Conferência
Universidade do Minho, Portugal
2021/11/26 - 2021/11/26 Speaker at t secondary school of Barcelos, Portugal about phage biotechonolgy
Seminário
 CEB AT SCHOOL
Universidade do Minho, Portugal
2021/09/24 - 2021/09/24 Increase awareness of research and innovation activities to the general public
Exposição
 European Researchers' Night 2021
Universidade do Minho, Portugal
2018/11/24 - 2018/11/24 Instructor
Oficina (workshop)
 CEB open day (outreach activity)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2018/07/26 - 2018/07/26 Instructor
Oficina (workshop)
 Verão no Campus (outreach activity)
Universidade do Minho Centro de Engenharia Biológica, Portugal
2016/02 - 2016/02 Participant
Oficina (workshop)
 Course in Laboratory Animal Science - FELASA, category C
Universidade do Minho Escola de Medicina, Portugal
2013/09 - 2013/12 Participant
Oficina (workshop)
 Training program in technology commercialization (COHiTEC)
Universidade Católica Portuguesa Católica Porto Business School, Portugal
2010/05 - 2010/05 Participant
Oficina (workshop)
 Methods of DNA analyses: state of the art
Universidade do Minho Escola de Medicina, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023 Insights on the mechanisms underlying the development of heteroresistance to colistin in Acinetobacter baumannii
Arguente principal
 Sarah Viegas (Mestrado)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022 PhageDPO: Phage Depolymerase Finder
Orientador
 José Duarte (Mestrado)
Universidade do Minho, Portugal
2022 Isolation of novel immunogenic protein carriers for vaccine development
Orientador
 Marta Gomes (Mestrado)
Universidade do Minho, Portugal
2021/07 Aptamers for Staphylococcal Enterotoxin A: Effect of nucleic acid mimics
Arguente
 Roberto Pinto (Outro)
Instituto Politécnico do Porto, Portugal
2021 PhagePro: Prophage ¿nding tool
Arguente
 João Dias (Mestrado)
Universidade do Minho, Portugal
2021 Characterization of novel Acinetobacter baumannii phage-derived depolymerases with anti-virulence properties
Orientador
 Rita Domingues (Mestrado)
Universidade do Minho, Portugal
2017 Genomic comparisons of novel Providencia infecting bacteriophages
Orientador
 Bruna Silva (Mestrado)
Universidade do Minho, Portugal
2017 Targeting Acinetobacter species with bacteriophage derived proteins
Orientador
 Alice Ferreira (Mestrado)
Universidade do Minho, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2022 - Atual Microbiologia 2022 Online conference
2022 - Atual Microsummit 2022
2021 - Atual World Microbe Forum Online conference
2024 - 2024 13th Congress of the Serbian Society for Microbiology
2022/03 - 2022/03 Viruses of Microbes 2022

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2021 - Atual Expert evaluator of grant research proposals
Avaliador
 Poland National Science Centre, Polónia Poland National Science Centre
2021 - Atual Evaluator of Marie Sklodowska-Curie Individual Fellowships (HE-MSCA-PF 2021) from the European Commission
Avaliador
 European Commission, Bélgica European Commission
2024 - 2026 Expert evaluator of grant research proposals
Avaliador
 ESF College of Expert Reviewers
2023 - 2023 Expert evaluator of grant research proposals
Avaliador
 Belgian Public Research Programme (BPRP)
2023 - 2023 Expert evaluator of grant research proposals
Avaliador
 Swiss National Science Foundation (SNSF)
2023 - 2023 Expert evaluator of grant research proposals
Avaliador
 University of Ljubljana for new, expanded and start-up research programmes (ICUL)
2022/02 - 2022/02 Expert evaluator of FCT PhD studenships
Avaliador
 Universidade do Minho, Portugal Associação para a Inovação e Desenvolvimento da FCT
2022 - 2022 Expert evaluator of grant research proposals
Avaliador
2021/07/26 - 2021/09/07 Expert evaluator of grant research proposals in response to the call entitled: Resistance Pathogens.
Avaliador
 Ministry of science and technology of Israel, Israel Ministry of science and technology of Israel
2020/09 - 2020/11 Expert evaluator of Individual Marie Sklodowska-Curie Fellowships (H2020-MSCA-IF-2020)
Avaliador
 European Commission, Bélgica European Commission

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020 - Atual Laboratório de Bioprocessos em Bioprocessos Biotecnologia (Mestrado integrado) Universidade do Minho, Portugal
2019 - Atual Transferência de Calor e Massa Engenharia Biomédica (Mestrado integrado) Universidade do Minho, Portugal
2015 - Atual Técnicas Avançadas em Bioengenharia Biotecnologia (Mestrado integrado) Universidade do Minho, Portugal
2014 - Atual Tópicos Avançados em Engenharia Química e Biológica II Engenharia Química e Biológica (Doutoramento) Universidade do Minho, Portugal
2024 - 2024 Virologia Aplicada Licenciatura em Biologia Aplicada (Ensino básico 2º ciclo) Universidade do Minho, Portugal
2016 - 2019 Projeto de Biotecnologia Biotecnologia (Mestrado integrado) Universidade do Minho, Portugal
2016 - 2018 Projeto de Bioinformatica Bioinformática (Mestrado integrado) Universidade do Minho, Portugal
2014 - 2018 Laboratórios Integrados de Bioengenharia Biotecnologia (Mestrado integrado) Universidade do Minho, Portugal
2016 - 2017 Fenómenos Interfaciais Engenharia Biomédica (Mestrado integrado) Universidade do Minho, Portugal
2014 - 2017 Laboratórios Integrados I Engenharia Biomédica (Mestrado integrado) Universidade do Minho, Portugal

Membro de associação

Nome da associação Tipo de participação
2021 - Atual SPM - Sociedade Portuguesa de Microbiologia Member
2019 - Atual ANICT - National Association of Researchers in Science and Technology Member
2018 - Atual ICTV - International Committee on Taxonomy of Viruses, United States Evaluator
2018 - Atual ESCMID - European Society of Clinical Microbiology and Infectious Diseases Member
2015 - Atual CEB - Integrated member of the Scientific Committee of the Centre of Biological Engineering, University of Minho Member

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2018 - Atual Editor
Membro
 Virology Journal, Reino Unido

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2022 - Atual Nature comunications Nature Publishing Group
2022 - Atual Frontiers in Cellular and Infection Microbiology Frontiers Media SA
2021 - Atual Current Opinion in Microbiology Elsevier
2021 - Atual Current Opinion in Biotechnology Elsevier
2021 - Atual ACS Infectious Diseases ACS publications
2020 - Atual Journal of Virology ASM
2019 - Atual Frontiers in Microbiology Frontiers Media SA
2019 - Atual Environmental Microbiology Wiley
2019 - Atual International Journal of Molecular Sciences MDPI
2019 - Atual Viruses MPDI
2018 - Atual Applied and Environmental Microbiology ASM
2018 - Atual Open Life Sciences Walter de Gruyter GmbH
2017 - Atual Journal of General Virology Microbiology Society
2017 - Atual Microbial Drug Resistance Mary Ann Liebert
2016 - Atual Applied Microbiology and Biotechnology Springer-Verlag
2015 - Atual Scientific Reports Springer Nature
2015 - Atual Journal of Infection and Chemotherapy Elsevier
2015 - Atual PLoS ONE Public Library of Science
2014 - Atual Virology Journal Springer (Biomed Central Ltd.)
2013 - Atual Antimicrobial Agents and Chemotherapy ASM

Tutoria

Tópico Nome do aluno
2019 - 2020 Phage-based depolymerases as antibiotics Rita Alexandra Carpinteiro Domingues
2018 - 2019 Biotechnology of bacteriophages Seila Agún García
2017 - 2018 Biotechnology of bacteriophages Jennifer Otero Carrera
2016 - 2017 Control of bacterial infectious with phage endolysins Mafalda Almeida
Distinções

Prémio

2020 Science comunication for non-specialists
Portuguese Society of Microbiology, Portugal
2015 Post-Doc fellowship (SFRH/BPD/ 111653/2015)
Fundação para a Ciência e a Tecnologia, Portugal
2013 Best poster award at MicroBiotec'13 - Congress of Microbiology and Biotechnology
Universidade de Aveiro, Portugal
2011 Best poster award at the MicroBiotec'11 - Congress of Microbiology and Biotechnology
Universidade do Minho, Portugal
2010 PhD fellowship (SFRH/BD/63734/2009)
Fundação para a Ciência e a Tecnologia, Portugal

Outra distinção

2020 Spotlight recognition - Oliveira H et al. AEM journal. doi: 10.1128/AEM.00073-20
Applied and Environmental journal (AEM), Estados Unidos
2019 Spotlight recognition - Oliveira H et al. AEM journal. doi: 10.1128/AEM.00934-19
Applied and Environmental journal (AEM), Estados Unidos
2013 Highly cited - Oliveira H et al. JV journal. doi: 10.1128/JVI.03277-12
Journal of Virology (JV), Estados Unidos