| Artigo em conferência |
- Luís, João; Mata, Ana; Alves, Nuno; Simões, Carlos; Pereira-Vaz, João; Vaz, Daniela; Duque, Vítor; Brito, Rui. "Influence
of codon 35 amino acid insertion in HIV-1 protease: insights from molecular dynamics". 2018.
10.3390/mol2net-04-06007
- Guerreiro Alves, Nuno; Luís, João; Simões, Carlos; Pereira-Vaz, João; Vaz, Daniela; Duque, Vitor; Brito, Rui. "Predicting
HIV-1 resistance to protease inhibitors: A new structure-based algorithm exploring binding-site Molecular Interaction Fields
dissimilarities". 2017.
10.3390/mol2net-03-05077
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| Artigo em revista |
- Alves, Américo J.S.; Alves, Nuno G.; Laranjo, Mafalda; Gomes, Clara S.B.; Cristina Gonçalves, Ana; Bela Sarmento-Ribeiro,
Ana; Filomena Botelho, M.; Pinho e Melo, Teresa M.V.D.. "Insights into the anticancer activity of chiral alkylidene-ß-lactams
and alkylidene-¿-lactams: Synthesis and biological investigation". Bioorganic & Medicinal Chemistry 63 (2022):
116738. http://dx.doi.org/10.1016/j.bmc.2022.116738.
10.1016/j.bmc.2022.116738
- Nuno Guerreiro Alves; Inês Bártolo; Américo J.S. Alves; Diana Fontinha; Denise Francisco; Susana M.M. Lopes; Maria I.L. Soares;
et al. "Synthesis and structure-activity relationships of new chiral spiro-ß-lactams highly active against HIV-1 and Plasmodium".
European Journal of Medicinal Chemistry 219 (2021): 113439-113439. https://doi.org/10.1016/j.ejmech.2021.113439.
10.1016/j.ejmech.2021.113439
- Alves, Nuno G.; Alves, Américo J. S.; Soares, Maria I. L.; Pinho e Melo, Teresa M. V. D.. "Recent Advances in the Synthesis
of Spiro-ß-Lactams and Spiro-d-Lactams". Advanced Synthesis & Catalysis (2021): http://dx.doi.org/10.1002/adsc.202100013.
10.1002/adsc.202100013
- Bártolo, Inês; Santos, Bruna S.; Fontinha, Diana; Machado, Marta; Francisco, Denise; Sepodes, Bruno; Rocha, João; et al. "Spiro-ß-lactam
BSS-730A Displays Potent Activity against HIV and Plasmodium". ACS Infectious Diseases 7 2 (2021): 421-434. http://dx.doi.org/10.1021/acsinfecdis.0c00768.
10.1021/acsinfecdis.0c00768
- Américo J. S. Alves; Nuno G. Alves; Maria I. L. Soares; Teresa M. V. D. Pinho e Melo. "Strategies and methodologies for the
construction of spiro-¿-lactams: an update". Organic Chemistry Frontiers (2021): https://doi.org/10.1039/D0QO01564D.
10.1039/D0QO01564D
- Rotureau, Elise; Rocha, Luciana S.; Goveia, Danielle; Alves, Nuno G.; Pinheiro, José Paulo. "Investigating the Binding Heterogeneity
of Trace Metal Cations With SiO2 Nanoparticles Using Full Wave Analysis of Stripping Chronopotentiometry at Scanned Deposition
Potential". Frontiers in Chemistry 8 (2020): http://dx.doi.org/10.3389/fchem.2020.614574.
10.3389/fchem.2020.614574
- Alves, Nuno G.; Mata, Ana I.; Luís, João P.; Brito, Rui M. M.; Simões, Carlos J. V.. "An Innovative Sequence-to-Structure-Based
Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease
Binding-Site Dissimilarities". Frontiers in Chemistry 8 (2020): http://dx.doi.org/10.3389/fchem.2020.00243.
Acesso aberto • 10.3389/fchem.2020.00243
- Alves, Américo J.S.; Alves, Nuno G.; Caratão, Cátia C.; Esteves, Margarida I.M.; Fontinha, Diana; Bártolo, Inês; Soares, Maria
I.L.; et al. "Spiro-Lactams as Novel Antimicrobial Agents". Current Topics in Medicinal Chemistry 20 2 (2020): 140-152.
http://dx.doi.org/10.2174/1568026619666191105110049.
10.2174/1568026619666191105110049
- Alves, Nuno G.; Rocha, Luciana S.; Moreira, José A.; da Costa, Ana M. Rosa; Pinheiro, José Paulo. "Effect of monomer organization
on the behavior of PSS-PS micelles". Colloids and Surfaces A: Physicochemical and Engineering Aspects 506 (2016): 313-319.
http://dx.doi.org/10.1016/j.colsurfa.2016.06.059.
10.1016/j.colsurfa.2016.06.059
- Rocha, Luciana S.; Botero, Wander G.; Alves, Nuno G.; Moreira, José A.; da Costa, Ana M. Rosa; Pinheiro, José Paulo. "LIGAND
SIZE POLYDISPERSITY EFFECT ON SSCP SIGNAL INTERPRETATION". Electrochimica Acta 166 (2015): 395-402. http://dx.doi.org/10.1016/j.electacta.2015.03.035.
10.1016/j.electacta.2015.03.035
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| Poster em conferência |
- Guerreiro Alves, Nuno; Alves, Américo; Bártolo, Inês; Simões, Carlos J.V.; Prudêncio, Miguel; Taveira, Nuno; Pinho e Melo,
Teresa M.V.D.. "A novel spiro-b-lactam with potent anti-HIV and anti-plasmodial activity". Trabalho apresentado em 13th
National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting, 2020.
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| Resumo em conferência |
- Alves, Américo J. S.; Bártolo, Inês; Alves, Nuno; Taveira, Nuno; Pinho e Melo, Teresa M. V. D.. "Novel Chiral Spiro-beta-Lactams
from Alkylidenepenicilanates via Cycloaddition reactions: Synthesis and Anti-HIV activity". Trabalho apresentado em International
Symposium on Synthesis and Catalysis 2021 (ISySyCat2021), Évora, 2021.
- Mata, Ana; Guerreiro Alves, Nuno; Luís, João P.; Simões, Carlos J.V.; Brito, Rui M. M.. "On the use of molecular interation
fields to predict drug resistance". Trabalho apresentado em 13th National Organic Chemistry Meeting - 6th National Medicinal
Chemistry Meeting, Aveiro, 2020.
- Alves, Nuno. "Understanding the mechanism of action of a new spiro-ß-lactam with dual anti-HIV and anti-Plasmodium activity
using in silico target fishing". Trabalho apresentado em XXVI Encontro Nacional da Sociedade Portuguesa de Química,
Porto, 2019.
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