???global.info.a_carregar???
Identificação

Identificação pessoal

Nome completo
Eugenio Uriarte Villares

Nomes de citação

  • Villares, Eugenio

Identificadores de autor

Ciência ID
0810-5F01-5443
ORCID iD
0000-0001-6218-2899
Formação
Grau Classificação
1983
Concluído
 Farmacia (Doktor (PhD))
Universidade de Santiago de Compostela, Espanha
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2008 - Atual Professor Catedrático (Docente Universitário) Universidade de Santiago de Compostela, Espanha
Projetos

Projeto

Designação Financiadores
2011/01/20 - 2014/01/19 BP4Brain - Benzopirano uma estrutura priveligiada para o desenho racional de compostos multi-alvo com aplicação potencial em doenças neurodegenerativas
PTDC/QUI-QUI/113687/2009
Universidade do Porto Centro de Investigação em Química, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Mellado, M.; González, C.; Mella, J.; Aguilar, L.F.; Celik, I.; Borges, F.; Uriarte, E.; et al. "Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin". Molecules 27 3 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85123595460&partnerID=MN8TOARS.
    10.3390/molecules27030928
  2. Pozo-Martínez, J.; Salgado, F.; Liempi, A.; Kemmerling, U.; Mera-Adasme, R.; Olea-Azar, C.; Moncada-Basualto, M.; et al. "Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in ß-cyclodextrin complexes and combination with benznidazole". Arabian Journal of Chemistry 15 3 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85121970186&partnerID=MN8TOARS.
    10.1016/j.arabjc.2021.103641
  3. Mellado M; González C; Mella J; Aguilar LF; Viña D; Uriarte E; Cuellar M; Matos MJ. "Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors.". Bioorganic chemistry (2021): http://europepmc.org/abstract/med/33571810.
    10.1016/j.bioorg.2021.104689
  4. Carneiro A; Matos MJ; Uriarte E; Santana L. "Trending Topics on Coumarin and Its Derivatives in 2020.". Molecules (Basel, Switzerland) (2021): http://europepmc.org/abstract/med/33477785.
    10.3390/molecules26020501
  5. Mesiti F; Maruca A; Silva V; Rocca R; Fernandes C; Remião F; Uriarte E; et al. "4-Oxoquinolines and monoamine oxidase: When tautomerism matters.". European journal of medicinal chemistry (2021): http://europepmc.org/abstract/med/33493825.
    10.1016/j.ejmech.2021.113183
  6. Villares, Eugenio. "Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents". Arabian Journal of Chemistry (2021):
    10.1016/j.arabjc.2020.102975
  7. López-Lira, C.; Tapia, R.A.; Herrera, A.; Lapier, M.; Maya, J.D.; Soto-Delgado, J.; Oliver, A.G.; Graham Lappin, A.; Uriarte, E.. "New benzimidazolequinones as trypanosomicidal agents". Bioorganic Chemistry 111 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106326429&partnerID=MN8TOARS.
    10.1016/j.bioorg.2021.104823
  8. Lopez Cisneros, C.L.; Cazar Ramírez, M.E.; Bailon-Moscoso, N.; Guardado, E.; Borges, F.; Uriarte, E.; Matos, M.J.. "Study of a Selected Series of 3- and 4-Arylcoumarins as Antifungal Agents against Dermatophytic Fungi: T. rubrum and T. mentagrophytes". ChemistrySelect 6 37 (2021): 9981-9989. http://www.scopus.com/inward/record.url?eid=2-s2.0-85116404984&partnerID=MN8TOARS.
    10.1002/slct.202103099
  9. Quezada, E.; Rodríguez-Enríquez, F.; Laguna, R.; Cutrín, E.; Otero, F.; Uriarte, E.; Viña, D.. "Curcumin–coumarin hybrid analogues as multitarget agents in neurodegenerative disorders". Molecules 26 15 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111755335&partnerID=MN8TOARS.
    10.3390/molecules26154550
  10. Yordi, E.G.; Santana, L.; Uriarte, E.; Borges, F.; Matos, M.J.. "Computer-aided Design of Coumarins for Neurodegenerative Diseases: Trends of the Last Decade". Current topics in medicinal chemistry 21 25 (2021): 2245-2257. http://www.scopus.com/inward/record.url?eid=2-s2.0-85122489527&partnerID=MN8TOARS.
    10.2174/1568026621666211011101429
  11. Matos, M.J.; Uriarte, E.; Santana, L.. "3-phenylcoumarins as a privileged scaffold in medicinal chemistry: The landmarks of the past decade". Molecules 26 21 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85119599138&partnerID=MN8TOARS.
    10.3390/molecules26216755
  12. Yañez O; Osorio MI; Uriarte E; Areche C; Tiznado W; Pérez-Donoso JM; García-Beltrán O; González-Nilo F. "In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease.". Frontiers in chemistry (2020): http://europepmc.org/abstract/med/33614592.
    10.3389/fchem.2020.595097
  13. Matos, M.J.; Vilar, S.; Vazquez-Rodriguez, S.; Kachler, S.; Klotz, K.-N.; Buccioni, M.; Delogu, G.; et al. "Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists". Journal of Medicinal Chemistry 63 5 (2020): 2577-2587. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076242889&partnerID=MN8TOARS.
    10.1021/acs.jmedchem.9b01572
  14. Era, B.; Delogu, G.L.; Pintus, F.; Fais, A.; Gatto, G.; Uriarte, E.; Borges, F.; Kumar, A.; Matos, M.J.. "Looking for new xanthine oxidase inhibitors: 3-Phenylcoumarins versus 2-phenylbenzofurans". International Journal of Biological Macromolecules 162 (2020): 774-780. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087367847&partnerID=MN8TOARS.
    10.1016/j.ijbiomac.2020.06.152
  15. Vazquez-Rodriguez, S.; Vilar, S.; Kachler, S.; Klotz, K.-N.; Uriarte, E.; Borges, F.; Matos, M.J.. "Adenosine receptor ligands: Coumarin–Chalcone hybrids as modulating agents on the activity of hARs". Molecules 25 18 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85091582471&partnerID=MN8TOARS.
    10.3390/molecules25184306
  16. Mellado, M.; Mella, J.; González, C.; Viña, D.; Uriarte, E.; Matos, M.J.. "3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?". Bioorganic Chemistry 101 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85085497505&partnerID=MN8TOARS.
    10.1016/j.bioorg.2020.103964
  17. Benfeito, S.; Fernandes, C.; Vilar, S.; Remião, F.; Uriarte, E.; Borges, F.. "Exploring the multi-target performance of mitochondriotropic antioxidants against the pivotal Alzheimer’s disease pathophysiological hallmarks". Molecules 25 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85077871023&partnerID=MN8TOARS.
    10.3390/molecules25020276
  18. Rodríguez-Enríquez, F.; Viña, D.; Uriarte, E.; Fontenla, J.A.; Matos, M.J.. "Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies". Bioorganic Chemistry 101 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85086580394&partnerID=MN8TOARS.
    10.1016/j.bioorg.2020.103986
  19. Matos, M.J.; Herrera Ibatá, D.M.; Uriarte, E.; Viña, D.. "Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents". ChemMedChem 15 6 (2020): 532-538. http://www.scopus.com/inward/record.url?eid=2-s2.0-85080135466&partnerID=MN8TOARS.
    10.1002/cmdc.202000018
  20. Rodríguez-Enríquez, F.; Viña, D.; Uriarte, E.; Laguna, R.; Matos, M.J.. "7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation". ChemMedChem (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85089783911&partnerID=MN8TOARS.
    10.1002/cmdc.202000454
  21. Pisano, M.B.; Kumar, A.; Medda, R.; Gatto, G.; Pal, R.; Fais, A.; Era, B.; et al. "Antibacterial Activity and Molecular Docking Studies of a Selected Series of Hydroxy-3-arylcoumarins". Molecules 24 15 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071158849&partnerID=MN8TOARS.
    10.3390/molecules24152815
  22. Yordi, E.G.; Koelig, R.; Matos, M.J.; Martínez, A.P.; Caballero, Y.; Santana, L.; Quintana, M.P.; Molina, E.; Uriarte, E.. "Artificial intelligence applied to flavonoid data in food matrices". Foods 8 11 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075068681&partnerID=MN8TOARS.
    10.3390/foods8110573
  23. Oliveira, C.; Bagetta, D.; Cagide, F.; Teixeira, J.; Amorim, R.; Silva, T.; Garrido, J.; et al. "Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents". European Journal of Medicinal Chemistry 174 (2019): 116-129. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064621799&partnerID=MN8TOARS.
    10.1016/j.ejmech.2019.04.026
  24. Duarte, Y.; Fonseca, A.; Gutiérrez, M.; Adasme-Carreño, F.; Muñoz-Gutierrez, C.; Alzate-Morales, J.; Santana, L.; et al. "Novel Coumarin-Quinoline Hybrids: Design of Multitarget Compounds for Alzheimer's Disease". ChemistrySelect 4 2 (2019): 551-558. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060222461&partnerID=MN8TOARS.
    10.1002/slct.201803222
  25. Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al. "Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction". European Journal of Medicinal Chemistry 167 (2019): 525-545. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061639088&partnerID=MN8TOARS.
    10.1016/j.ejmech.2019.01.055
  26. Dhiman, P.; Malik, N.; Sobarzo-Sánchez, E.; Uriarte, E.; Khatkar, A.. "Quercetin and related chromenone derivatives as monoamine oxidase inhibitors: Targeting neurological and mental disorders". Molecules 24 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060523265&partnerID=MN8TOARS.
    10.3390/molecules24030418
  27. Mellado, M.; Salas, C.O.; Uriarte, E.; Viña, D.; Jara-Gutiérrez, C.; Matos, M.J.; Cuellar, M.. "Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity". ChemistrySelect 4 26 (2019): 7698-7703. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068955355&partnerID=MN8TOARS.
    10.1002/slct.201901282
  28. Chavarria, D.; Fernandes, C.; Aguiar, B.; Silva, T.; Garrido, J.; Remião, F.; Oliveira, P.J.; Uriarte, E.; Borges, F.. "Insights into the discovery of novel neuroprotective agents: A comparative study between sulfanylcinnamic acid derivatives and related phenolic analogues". Molecules 24 23 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076316732&partnerID=MN8TOARS.
    10.3390/molecules24234405
  29. Munin, J.; Quezada, E.; Viña, D.; Uriarte, E.; Delogu, G.L.; Gil-Longo, J.. "Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels". Future Medicinal Chemistry 11 3 (2019): 179-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063491770&partnerID=MN8TOARS.
    10.4155/fmc-2018-0250
  30. Amin, S.; Ullah, B.; Ali, M.; Rauf, A.; Khan, H.; Uriarte, E.; Sobarzo-Sánchez, E.. "Potent in Vitro a-Glucosidase Inhibition of Secondary Metabolites Derived from Dryopteris cycadina". Molecules 24 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060552485&partnerID=MN8TOARS.
    10.3390/molecules24030427
  31. Hajialyani, M.; Farzaei, M.H.; Echeverría, J.; Nabavi, S.M.; Uriarte, E.; Eduardo, S.-S.. "Hesperidin as a neuroprotective agent: A review of animal and clinical evidence". Molecules 24 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85061540322&partnerID=MN8TOARS.
    10.3390/molecules24030648
  32. Fernandes C; Martins CAU; Fonseca A; Nunes R; Matos MJ; Silva R; Garrido J; et al. "PEGylated PLGA nanoparticles as a smart carrier to increase the cellular uptake of a coumarin-based monoamine oxidase B inhibitor.". ACS applied materials & interfaces (2018): http://europepmc.org/abstract/med/30352150.
    10.1021/acsami.8b17224
  33. Reis J; Cagide F; Valencia ME; Teixeira J; Bagetta D; Pérez C; Uriarte E; et al. "Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.". European journal of medicinal chemistry (2018): http://europepmc.org/abstract/med/30245401.
    10.1016/j.ejmech.2018.07.056
  34. Fais A; Era B; Asthana S; Sogos V; Medda R; Santana L; Uriarte E; et al. "Coumarin derivatives as promising xanthine oxidase inhibitors.". International journal of biological macromolecules (2018): http://europepmc.org/abstract/med/30189275.
    10.1016/j.ijbiomac.2018.09.001
  35. Nabavi SM; Uriarte E; Rastrelli L; Sobarzo-Sanchez E. "Aporphines and Alzheimer's disease: Towards a Medical Approach Facing the Future.". Current medicinal chemistry (2018): http://europepmc.org/abstract/med/29756568.
    10.2174/0929867325666180514102933
  36. Reis J; Cagide F; Chavarria D; Silva T; Fernandes C; Gaspar A; Uriarte E; et al. "Correction to Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.". Journal of medicinal chemistry (2018): http://europepmc.org/abstract/med/29809006.
    10.1021/acs.jmedchem.8b00600
  37. Reis J; Manzella N; Cagide F; Mialet-Perez J; Uriarte E; Parini A; Borges F; Binda C. "Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis.". Journal of medicinal chemistry (2018): http://europepmc.org/abstract/med/29648817.
    10.1021/acs.jmedchem.8b00357
  38. Oliveira C; Cagide F; Teixeira J; Amorim R; Sequeira L; Mesiti F; Silva T; et al. "Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors.". Frontiers in chemistry (2018): http://europepmc.org/abstract/med/29740575.
    10.3389/fchem.2018.00126
  39. Vilar S; Sobarzo-Sanchez E; Santana L; Uriarte E. "Ligand and Structure-based Modeling of Passive Diffusion through the Blood-Brain Barrier.". Current medicinal chemistry (2018): http://europepmc.org/abstract/med/29110594.
    10.2174/0929867324666171106163742
  40. Moncada-Basualto M; Lapier M; Maya JD; Matsuhiro B; Olea-Azar C; Delogu GL; Uriarte E; Santana L; Matos MJ. "Evaluation of Trypanocidal and Antioxidant Activities of a Selected Series of 3-amidocoumarins.". Medicinal chemistry (Shariqah (United Arab Emirates)) (2018): http://europepmc.org/abstract/med/29669503.
    10.2174/1573406414666180419113437
  41. Lizama-Bizama, I.; Pérez, C.; Baeza, C.M.; Uriarte, E.; Becerra, J.. "Alkaloids from chilean species of the genus Rhodophiala C. Presl (Amaryllidaceae) and their chemotaxonomic importance,Alcaloides de especies chilenas del género Rhodophiala C. Presl (amaryllidaceae) y su importancia quimiotaxonómica". Gayana - Botanica 75 1 (2018): 459-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057746299&partnerID=MN8TOARS.
    10.4067/S0717-66432018000100459
  42. Figueroa-Benavides, C.; Matos, M.J.; Peñaloza-Amion, M.; Veas, R.; Valenzuela-Barra, G.; Zapata, G.; Delogu, G.; et al. "Targeting a -(1,4)-glucosidase in diabetes mellitus type 2: The role of new synthetic coumarins as potent inhibitors". Current Topics in Medicinal Chemistry 18 27 (2018): 2327-2337. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061569837&partnerID=MN8TOARS.
    10.2174/1568026619666181130113033
  43. Vilar S; Sobarzo-Sanchez E; Uriarte E. "In Silico Prediction of P-glycoprotein Binding: Insights from Molecular Docking Studies.". Current medicinal chemistry (2017): http://europepmc.org/abstract/med/29189117.
    10.2174/0929867325666171129121924
  44. Fonseca A; Matos MJ; Vilar S; Kachler S; Klotz KN; Uriarte E; Borges F. "Coumarins and adenosine receptors: New perceptions in structure-affinity relationships.". Chemical biology & drug design (2017): http://europepmc.org/abstract/med/28734062.
    10.1111/cbdd.13075
  45. Fonseca A; Reis J; Silva T; Matos MJ; Bagetta D; Ortuso F; Alcaro S; Uriarte E; Borges F. "Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?". Journal of medicinal chemistry (2017): http://europepmc.org/abstract/med/28753307.
    10.1021/acs.jmedchem.7b00918
  46. Costas-Lago MC; Besada P; Rodríguez-Enríquez F; Viña D; Vilar S; Uriarte E; Borges F; Terán C. "Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors.". European journal of medicinal chemistry (2017): http://europepmc.org/abstract/med/28797881.
    10.1016/j.ejmech.2017.07.045
  47. Bacho M; Coelho-Cerqueira E; Follmer C; Nabavi SM; Rastrelli L; Uriarte E; Sobarzo-Sanchez E. "A Medical Approach to the Monoamine Oxidase Inhibition by Using 7Hbenzo[ e]perimidin-7-one Derivatives.". Current topics in medicinal chemistry (2017): http://europepmc.org/abstract/med/27558674.
    10.2174/1568026616666160824120929
  48. Vilar S; Sobarzo-Sanchez E; Santana L; Uriarte E. "Molecular Docking and Drug Discovery in ß-Adrenergic Receptors.". Current medicinal chemistry (2017): http://europepmc.org/abstract/med/28738772.
    10.2174/0929867324666170724101448
  49. Pintus F; Matos MJ; Vilar S; Hripcsak G; Varela C; Uriarte E; Santana L; et al. "New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies.". Bioorganic & medicinal chemistry (2017): http://europepmc.org/abstract/med/28189394.
    10.1016/j.bmc.2017.01.037
  50. Matos, M.J.; Vazquez-Rodriguez, S.; Fonseca, A.; Uriarte, E.; Santana, L.; Borges, F.. "Heterocyclic antioxidants in nature: Coumarins". Current Organic Chemistry 21 4 (2017): 311-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011026227&partnerID=MN8TOARS.
    10.2174/1385272820666161017170652
  51. Nabavi, S.M.; Uriarte, E.; Fontenla, J.A.; Rastrelli, L.; Sobarzo-Sánchez, E.. "Aporphine alkaloids and their antioxidant medical application: From antineoplastic agents to motor dysfunction diseases". Current Organic Chemistry 21 4 (2017): 342-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011061593&partnerID=MN8TOARS.
    10.2174/1385272820666161017165735
  52. Munín, J.; Quezada, E.; Campos-Toimil, M.; Cano, E.; Uriarte, E.; Viña, D.. "Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives". Medicinal Chemistry Research 26 8 (2017): 1682-1688. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016941619&partnerID=MN8TOARS.
    10.1007/s00044-017-1879-9
  53. E. Guardado Yordi; M. J. Matos; A. Pérez Martínez; A. C. Tornes; L. Santana; E. Molina; E. Uriarte; et al. "In silico genotoxicity of coumarins: application of the Phenol-Explorer food database to functional food science". Food & Function (2017): https://doi.org/10.1039/C7FO00402H.
    10.1039/C7FO00402H
  54. Robledo-O'Ryan N; Matos MJ; Vazquez-Rodriguez S; Santana L; Uriarte E; Moncada-Basualto M; Mura F; et al. "Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins.". Bioorganic & medicinal chemistry (2016): http://europepmc.org/abstract/med/27908757.
    10.1016/j.bmc.2016.11.033
  55. Fonseca A; Gaspar A; Matos MJ; Gomes LR; Low JN; Uriarte E; Borges F. "Structural elucidation of a series of 6-methyl-3-carboxamidocoumarins.". Magnetic resonance in chemistry : MRC (2016): http://europepmc.org/abstract/med/27733011.
    10.1002/mrc.4541
  56. Vilar S; Quezada E; Uriarte E; Costanzi S; Borges F; Viña D; Hripcsak G. "Computational Drug Target Screening through Protein Interaction Profiles.". Scientific reports (2016): http://europepmc.org/abstract/med/27845365.
    10.1038/srep36969
  57. Silva T; Mohamed T; Shakeri A; Rao PP; Martínez-González L; Pérez DI; Martínez A; et al. "Development of Blood-Brain Barrier Permeable Nitrocatechol-Based Catechol O-Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity.". Journal of medicinal chemistry (2016): http://europepmc.org/abstract/med/27463695.
    10.1021/acs.jmedchem.6b00666
  58. Reis J; Cagide F; Chavarria D; Silva T; Fernandes C; Gaspar A; Uriarte E; et al. "Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.". Journal of medicinal chemistry (2016): http://europepmc.org/abstract/med/27244485.
    10.1021/acs.jmedchem.6b00527
  59. Fazel Nabavi S; Uriarte E; Rastrelli L; Modak B; Sobarzo-Sánchez E. "Aporphines and Parkinson's Disease: Medical Tools for the Future.". Current topics in medicinal chemistry (2016): http://europepmc.org/abstract/med/26845550.
    10.2174/1568026616666160204122935
  60. Fonseca, A.; Matos, M.J.; Reis, J.; Duarte, Y.; Gutiérrez, M.; Santana, L.; Uriarte, E.; Borges, F.. "Exploring coumarin potentialities: Development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold". RSC Advances 6 55 (2016): 49764-49768. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973562593&partnerID=MN8TOARS.
    10.1039/c6ra05262b
  61. Torres, S.; Cabrera-Pardo, J.R.; Alonso, F.; Bustos, E.; Pérez, C.; Palfner, G.; Hernández, V.; Uriarte, E.; Becerra, J.. "Changes in secondary metabolites profiles and biological activity of the fresh fruiting bodies of Stereum hirsutum exposed to high-dose UV-B radiation". Journal of the Chilean Chemical Society 61 4 (2016): 3224-3227. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010409264&partnerID=MN8TOARS.
    10.4067/S0717-97072016000400015
  62. Matos, M.J.; Vilar, S.; Kachler, S.; Vazquez-Rodriguez, S.; Varela, C.; Delogu, G.; Hripcsak, G.; et al. "Progress in the development of small molecules as new human A3 adenosine receptor ligands based on the 3-thiophenylcoumarin core". MedChemComm 7 5 (2016): 845-852. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971242753&partnerID=MN8TOARS.
    10.1039/c5md00573f
  63. Vazquez-Rodriguez, S.; Guíñez, R.F.; Matos, M.J.; Olea-Azar, C.; Maya, J.D.; Uriarte, E.; Santana, L.; et al. "Facing chagas' disease: Trypanocidal properties of new coumarinchalcone scaffolds". Medicinal Chemistry 12 6 (2016): 537-543. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983670782&partnerID=MN8TOARS.
    10.2174/1573406412666160107111809
  64. Muñoz, A.; Fonseca, A.; Matos, M.J.; Uriarte, E.; Santana, L.; Borges, F.; Figueroa, R.; Olea Azar, C.. "Evaluation of Antioxidant and Antitrypanosomal Properties of a Selected Series of Synthetic 3-Carboxamidocoumarins". ChemistrySelect 1 15 (2016): 4957-4964. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041947854&partnerID=MN8TOARS.
    10.1002/slct.201601336
  65. Matos MJ; Rodríguez-Enríquez F; Borges F; Santana L; Uriarte E; Estrada M; Rodríguez-Franco MI; Laguna R; Viña D. "3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases.". ChemMedChem (2015): http://europepmc.org/abstract/med/26493007.
    10.1002/cmdc.201500408
  66. Vazquez-Rodriguez S; Lama López R; Matos MJ; Armesto-Quintas G; Serra S; Uriarte E; Santana L; et al. "Design, synthesis and antibacterial study of new potent and selective coumarin-chalcone derivatives for the treatment of tenacibaculosis.". Bioorganic & medicinal chemistry (2015): http://europepmc.org/abstract/med/26433630.
    10.1016/j.bmc.2015.09.028
  67. Matos MJ; Vazquez-Rodriguez S; Uriarte E; Santana L; Borges F. "Synthesis and pharmacological activities of non-flavonoid chromones: a patent review (from 2005 to 2015).". Expert opinion on therapeutic patents (2015): http://europepmc.org/abstract/med/26291463.
    10.1517/13543776.2015.1078790
  68. Matos MJ; Vilar S; Kachler S; Celeiro M; Vazquez-Rodriguez S; Santana L; Uriarte E; et al. "Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold.". Bioorganic chemistry (2015): http://europepmc.org/abstract/med/26042529.
    10.1016/j.bioorg.2015.05.008
  69. Matos MJ; Mura F; Vazquez-Rodriguez S; Borges F; Santana L; Uriarte E; Olea-Azar C. "Study of coumarin-resveratrol hybrids as potent antioxidant compounds.". Molecules (Basel, Switzerland) (2015): http://europepmc.org/abstract/med/25690290.
    10.3390/molecules20023290
  70. Sobarzo-Sánchez E; Nabavi SM; Uriarte E; Santana L. "Nanoparticles in the treatment of mental disorders: a new tool in the psychiatric medication.". Current topics in medicinal chemistry (2015): http://europepmc.org/abstract/med/25579348.
    10.2174/1568026615666150108124533
  71. Gaspar A; Milhazes N; Santana L; Uriarte E; Borges F; Matos MJ. "Oxidative stress and neurodegenerative diseases: looking for a therapeutic solution inspired on benzopyran chemistry.". Current topics in medicinal chemistry (2015): http://europepmc.org/abstract/med/25658803.
    10.2174/1568026614666141229124141
  72. Figueroa-Guiñez R; Matos MJ; Vazquez-Rodriguez S; Santana L; Uriarte E; Borges F; Olea-Azar C; Maya JD. "Interest of antioxidant agents in parasitic diseases. The case study of coumarins.". Current topics in medicinal chemistry (2015): http://europepmc.org/abstract/med/25697564.
    10.2174/1568026615666150220113155
  73. Vazquez-Rodriguez S; Matos MJ; Borges F; Uriarte E; Santana L. "Bioactive Coumarins from Marine Sources: Origin, Structural Features and Pharmacological Properties.". Current topics in medicinal chemistry (2015): http://europepmc.org/abstract/med/25915605.
    10.2174/1568026615666150427125916
  74. Matos MJ; Vazquez-Rodriguez S; Uriarte E; Santana L. "Potential pharmacological uses of chalcones: a patent review (from June 2011 - 2014).". Expert opinion on therapeutic patents (2015): http://europepmc.org/abstract/med/25598152.
    10.1517/13543776.2014.995627
  75. Cagide, F.; Gaspar, A.; Reis, J.; Chavarria, D.; Vilar, S.; Hripcsak, G.; Uriarte, E.; et al. "Navigating in chromone chemical space: Discovery of novel and distinct A3 adenosine receptor ligands". RSC Advances 5 96 (2015): 78572-78585. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942156288&partnerID=MN8TOARS.
    10.1039/c5ra14988f
  76. Nuñez, J.; Fontenla, J.A.; Nabavi, S.M.; Uriarte, E.; Herrera, A.; Sobarzo-Sánchez, E.. "Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice". Current Topics in Medicinal Chemistry 15 17 (2015): 1750-1754. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931831872&partnerID=MN8TOARS.
    10.2174/1568026615666150427125535
  77. Yordi, E.G.; Matos, M.J.; Pupo, R.C.; Santana, L.; Uriarte, E.; Pérez, E.M.. "In silico clastogenic activity of dietary phenolic acids". LWT - Food Science and Technology 61 1 (2015): 216-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926014500&partnerID=MN8TOARS.
    10.1016/j.lwt.2014.11.012
  78. Munín, J.; Santana, L.; Uriarte, E.; Borges, F.; Quezada, E.. "A comparative synthesis of 6-benzyl-2,3-dihydroimidazo[2,1-a]phthalazine and 2H-7-benzyl-3,4-dihydropyrimido[2,1-a]phthalazine". Tetrahedron Letters 56 6 (2015): 828-830. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921296279&partnerID=MN8TOARS.
    10.1016/j.tetlet.2014.12.121
  79. Matos, M.J.; Varela, C.; Vilar, S.; Hripcsak, G.; Borges, F.; Santana, L.; Uriarte, E.; et al. "Design and discovery of tyrosinase inhibitors based on a coumarin scaffold". RSC Advances 5 114 (2015): 94227-94235. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946594387&partnerID=MN8TOARS.
    10.1039/c5ra14465e
  80. Matos MJ; Rodríguez-Enríquez F; Vilar S; Santana L; Uriarte E; Hripcsak G; Estrada M; Rodríguez-Franco MI; Viña D. "Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives.". Bioorganic & medicinal chemistry letters (2014): http://europepmc.org/abstract/med/25532905.
    10.1016/j.bmcl.2014.12.001
  81. Gaspar A; Milhazes N; Santana L; Uriarte E; Borges F; Matos MJ. "Oxidative Stress and Neurodegenerative Diseases: Looking for a Therapeutic Solution Inspired on Benzopyran Chemistry.". Current topics in medicinal chemistry (2014): http://europepmc.org/abstract/med/25547103.
  82. Vilar S; Uriarte E; Santana L; Lorberbaum T; Hripcsak G; Friedman C; Tatonetti NP. "Similarity-based modeling in large-scale prediction of drug-drug interactions.". (2014): http://europepmc.org/abstract/med/25122524.
    10.1038/nprot.2014.151
  83. Vilar, S.; Uriarte, E.; Santana, L.; Friedman, C.; Tatonetti, N.P.. "State of the art and development of a drug-drug interaction large scale predictor based on 3D pharmacophoric similarity". Current Drug Metabolism 15 5 (2014): 490-501. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924596658&partnerID=MN8TOARS.
    10.2174/138920021505141126102223
  84. Matos, M.J.; Janeiro, P.; Santana, L.; Uriarte, E.; Oliveira-Brett, A.M.. "Synthesis and electrochemical study of new 3-(hydroxyphenyl)benzo[f] coumarins". Journal of Electroanalytical Chemistry 726 (2014): 62-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902150437&partnerID=MN8TOARS.
    10.1016/j.jelechem.2014.05.003
  85. Munín, J.; Quezada, E.; Cuiñas, A.; Campos-Toimil, M.; Uriarte, E.; Santana, L.; Viña, D.. "Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity". European Journal of Medicinal Chemistry 82 (2014): 407-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902510004&partnerID=MN8TOARS.
    10.1016/j.ejmech.2014.05.052
  86. Delogu, G.L.; Serra, S.; Quezada, E.; Uriarte, E.; Vilar, S.; Tatonetti, N.P.; Viña, D.. "Monoamine oxidase (MAO) inhibitory activity: 3-phenylcoumarins versus 4-hydroxy-3-phenylcoumarins". ChemMedChem 9 8 (2014): 1672-1676. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905280467&partnerID=MN8TOARS.
    10.1002/cmdc.201402010
  87. Matos, M.J.; Janeiro, P.; González Franco, R.M.; Vilar, S.; Tatonetti, N.P.; Santana, L.; Uriarte, E.; et al. "Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases". Future Medicinal Chemistry 6 4 (2014): 371-383. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896967797&partnerID=MN8TOARS.
    10.4155/fmc.14.9
  88. Matos, M.J.; Vilar, S.; Kachler, S.; Fonseca, A.; Santana, L.; Uriarte, E.; Borges, F.; Tatonetti, N.P.; Klotz, K.-N.. "Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors". ChemMedChem (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84904274612&partnerID=MN8TOARS.
    10.1002/cmdc.201402205
  89. Gaspar, A.; Matos, M.J.; Garrido, J.; Uriarte, E.; Borges, F.. "Chromone: A valid scaffold in medicinal chemistry". Chemical Reviews 114 9 (2014): 4960-4992. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900440197&partnerID=MN8TOARS.
    10.1021/cr400265z
  90. Matos, M.J.; Vilar, S.; García-Morales, V.; Tatonetti, N.P.; Uriarte, E.; Santana, L.; Viña, D.. "Insight into the functional and structural properties of 3-arylcoumarin as an interesting scaffold in monoamine oxidase B inhibition". ChemMedChem 9 7 (2014): 1488-1500. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903816963&partnerID=MN8TOARS.
    10.1002/cmdc.201300533
  91. López MC; Fontenla JA; Uriarte E; Santana L; Sobarzo-Sánchez E; López, M.C.; Fontenla, J.A.; et al. "Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.". Current topics in medicinal chemistry 14 2 (2014): 234-238. http://europepmc.org/abstract/med/24359197.
    10.2174/1568026613666131213162753
  92. Guíñez RF; Matos MJ; Vazquez-Rodriguez S; Santana L; Uriarte E; Olea-Azar C; Maya JD; et al. "Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives.". Future Medicinal Chemistry 5 16 (2013): 1911-1922. http://europepmc.org/abstract/med/24175743.
    10.4155/fmc.13.147
  93. Ferino, G.; Cadoni, E.; Matos, M.J.; Quezada, E.; Uriarte, E.; Santana, L.; Vilar, S.; et al. "MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, invitro Study, and Docking Calculations". ChemMedChem 8 6 (2013): 956-966. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878358843&partnerID=MN8TOARS.
    10.1002/cmdc.201300048
  94. Vazquez-Rodriguez, S.; Figueroa-Guíñez, R.; Matos, M.J.; Santana, L.; Uriarte, E.; Lapier, M.; Maya, J.D.; Olea-Azar, C.. "Synthesis of coumarin-chalcone hybrids and evaluation of their antioxidant and trypanocidal properties". MedChemComm 4 6 (2013): 993-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878776771&partnerID=MN8TOARS.
    10.1039/c3md00025g
  95. Matos, M.J.; Pérez-Cruz, F.; Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L.; Borges, F.; Olea-Azar, C.. "Remarkable antioxidant properties of a series of hydroxy-3-arylcoumarins". Bioorganic and Medicinal Chemistry 21 13 (2013): 3900-3906. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878557237&partnerID=MN8TOARS.
    10.1016/j.bmc.2013.04.015
  96. Matos, M.J.; Uriarte, E.; Santana, L.; Vilar, S.. "Synthesis, NMR characterization, X-ray structural analysis and theoretical calculations of amide and ester derivatives of the coumarin scaffold". Journal of Molecular Structure 1041 (2013): 144-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875921084&partnerID=MN8TOARS.
    10.1016/j.molstruc.2013.03.014
  97. Vilar, S.; Uriarte, E.; Santana, L.; Tatonetti, N.P.; Friedman, C.. "Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints". PLoS ONE 8 3 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84874766004&partnerID=MN8TOARS.
    10.1371/journal.pone.0058321
  98. Matos, M.J.; Vilar, S.; Gonzalez-Franco, R.M.; Uriarte, E.; Santana, L.; Friedman, C.; Tatonetti, N.P.; Viña, D.; Fontenla, J.A.. "Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study". European Journal of Medicinal Chemistry 63 (2013): 151-161. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874527492&partnerID=MN8TOARS.
    10.1016/j.ejmech.2013.02.009
  99. Vazquez-Rodriguez, S.; Matos, M.J.; Santana, L.; Uriarte, E.; Borges, F.; Kachler, S.; Klotz, K.-N.. "Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists". Journal of Pharmacy and Pharmacology 65 5 (2013): 697-703. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876471857&partnerID=MN8TOARS.
    10.1111/jphp.12028
  100. Gaspar, A.; Cagide, F.; Quezada, E.; Reis, J.; Uriarte, E.; Borges, F.. "Synthesis and NMR studies of novel chromone-2-carboxamide derivatives". Magnetic Resonance in Chemistry 51 4 (2013): 251-254. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875254988&partnerID=MN8TOARS.
    10.1002/mrc.3937
  101. Pérez-Cruz, F.; Aguilera-Venegas, B.; Lapier, M.; Sobarzo-Sánchez, E.; Uriarte Villares, E.; Olea-Azar, C.. "Host-guest interaction between new nitrooxoisoaporphine and ß-cyclodextrins: Synthesis, electrochemical, electron spin resonance and molecular modeling studies". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 102 (2013): 226-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870373491&partnerID=MN8TOARS.
    10.1016/j.saa.2012.09.068
  102. Janeiro, P.; Matos, M.J.; Santana, L.; Uriarte, E.; Oliveira-Brett, A.M.. "New hydroxylated 3-arylcoumarins, synthesis and electrochemical study". Journal of Electroanalytical Chemistry 689 (2013): 243-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871787111&partnerID=MN8TOARS.
    10.1016/j.jelechem.2012.10.020
  103. Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L.. "3-(4-Methoxybenzoyl)-6-nitrocoumarin". Acta Crystallographica Section E: Structure Reports Online 69 3 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84874841051&partnerID=MN8TOARS.
    10.1107/S1600536813002948
  104. Matos, M.J.; Vazquez-Rodriguez, S.; Santana, L.; Uriarte, E.; Fuentes-Edfuf, C.; Santos, Y.; Muñoz-Crego, A.. "Synthesis and structure-activity relationships of novel amino/nitro substituted 3-arylcoumarins as antibacterial agents". Molecules 18 2 (2013): 1394-1404. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874632606&partnerID=MN8TOARS.
    10.3390/molecules18021394
  105. Matos, M.J.; Gaspar, A.; Kachler, S.; Klotz, K.-N.; Borges, F.; Santana, L.; Uriarte, E.. "Targeting adenosine receptors with coumarins: Synthesis and binding activities of amide and carbamate derivatives". Journal of Pharmacy and Pharmacology 65 1 (2013): 30-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870870474&partnerID=MN8TOARS.
    10.1111/j.2042-7158.2012.01571.x
  106. Matos, M.J.; Hogger, V.; Gaspar, A.; Kachler, S.; Borges, F.; Uriarte, E.; Santana, L.; Klotz, K.-N.. "Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins". Journal of Pharmacy and Pharmacology 65 11 (2013): 1590-1597. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886085159&partnerID=MN8TOARS.
    10.1111/jphp.12135
  107. Bonet, I.; Franco-Montero, P.; Rivero, V.; Teijeira, M.; Borges, F.; Uriarte, E.; Morales Helguera, A.. "Classifier ensemble based on feature selection and diversity measures for predicting the affinity of A2B adenosine receptor antagonists". Journal of Chemical Information and Modeling 53 12 (2013): 3140-3155. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896502130&partnerID=MN8TOARS.
    10.1021/ci300516w
  108. Matos, M.J.; Vilar, S.; Tatonetti, N.P.; Santana, L.; Uriarte, E.. "Comparative study of the 3-phenylcoumarin scaffold: Synthesis, X-ray structural analysis and semiempirical calculations of a selected series of compounds". Journal of Molecular Structure 1050 (2013): 185-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881490731&partnerID=MN8TOARS.
    10.1016/j.molstruc.2013.07.037
  109. Pérez-Cruz, F.; Vazquez-Rodriguez, S.; Matos, M.J.; Herrera-Morales, A.; Villamena, F.A.; Das, A.; Gopalakrishnan, B.; et al. "Synthesis and electrochemical and biological studies of novel coumarin-chalcone hybrid compounds". Journal of Medicinal Chemistry 56 15 (2013): 6136-6145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881404683&partnerID=MN8TOARS.
    10.1021/jm400546y
  110. Molina, E.; Uriarte, E.; Santana, L.; Matos, M.J.; Borges, F.. "QSAR and complex network recognition of miRNAs in stem cells". Current Bioinformatics 8 4 (2013): 438-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882741932&partnerID=MN8TOARS.
    10.2174/1574893611308040006
  111. Sobarzo-Sánchez E; Bilbao-Ramos P; Dea-Ayuela M; González-Díaz H; Yañez M; Uriarte E; Santana L; et al. "Synthetic oxoisoaporphine alkaloids: in vitro, in vivo and in silico assessment of antileishmanial activities.". PloS one 8 10 (2013): http://europepmc.org/abstract/med/24204870.
    10.1371/journal.pone.0077560
  112. Molina E; Sobarzo-Sánchez E; Speck-Planche A; Matos MJ; Uriarte E; Santana L; Yáñez M; et al. "Monoamino Oxidase A: an interesting pharmacological target for the development of multi-target QSAR.". Mini-Reviews in Medicinal Chemistry 12 10 (2012): 947-958. http://europepmc.org/abstract/med/22303975.
    10.2174/138955712802762383
  113. Matos, M.J.; Viña, D.; Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L.; Matos MJ; Viña D; et al. "Focusing on new monoamine oxidase inhibitors: Differently substituted coumarins as an interesting scaffold". Current Topics in Medicinal Chemistry 12 20 (2012): 2210-2239. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874893498&partnerID=MN8TOARS.
    10.2174/156802612805220002
  114. Matos, M.J.; Santana, L.; Uriarte, E.. "N-(2-Oxo-2H-chromen-3-yl)cyclohexanecarboxamide". Acta Crystallographica Section E: Structure Reports Online 68 12 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84870891646&partnerID=MN8TOARS.
    10.1107/S1600536812047903
  115. Matos, M.J.; Gaspar, A.; Borges, F.; Uriarte, E.; Santana, L.. "Improved synthesis of 3-(aminoaryl)coumarins". Organic Preparations and Procedures International 44 6 (2012): 522-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870010404&partnerID=MN8TOARS.
    10.1080/00304948.2012.730937
  116. Serra, S.; Chicca, A.; Delogu, G.; Vázquez-Rodríguez, S.; Santana, L.; Uriarte, E.; Casu, L.; Gertsch, J.. "Erratum: Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives (Bioorganic and Medicinal Chemistry Letters (2012) 22 (5791-5794))". Bioorganic and Medicinal Chemistry Letters 22 21 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84867571525&partnerID=MN8TOARS.
    10.1016/j.bmcl.2012.09.019
  117. Matos, M.J.; Vazquez-Rodriguez, S.; Santana, L.; Uriarte, E.; Fuentes-Edfuf, C.; Santos, Y.; Muñoz-Crego, A.. "Looking for new targets: Simple coumarins as antibacterial agents". Medicinal Chemistry 8 6 (2012): 1140-1145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868010131&partnerID=MN8TOARS.
    10.2174/1573406411208061140
  118. Vilar, S.; Harpaz, R.; Uriarte, E.; Santana, L.; Rabadan, R.; Friedman, C.. "Drug-drug interaction through molecular structure similarity analysis". Journal of the American Medical Informatics Association 19 6 (2012): 1066-1074. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867675481&partnerID=MN8TOARS.
    10.1136/amiajnl-2012-000935
  119. Matos, M.J.; Santana, L.; Uriarte, E.. "3-Phenyl-coumarin". Acta Crystallographica Section E: Structure Reports Online 68 9 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865745576&partnerID=MN8TOARS.
    10.1107/S1600536812034277
  120. Gaspar, A.; Reis, J.; Matos, M.J.; Uriarte, E.; Borges, F.. "In search for new chemical entities as adenosine receptor ligands: Development of agents based on benzo-¿-pyrone skeleton". European Journal of Medicinal Chemistry 54 (2012): 914-918. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864409949&partnerID=MN8TOARS.
    10.1016/j.ejmech.2012.05.033
  121. Serra, S.; Chicca, A.; Delogu, G.; Vázquez-Rodríguez, S.; Santana, L.; Uriarte, E.; Casu, L.; Gertsch, J.. "Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives". Bioorganic and Medicinal Chemistry Letters 22 18 (2012): 5791-5794. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865462648&partnerID=MN8TOARS.
    10.1016/j.bmcl.2012.07.099
  122. Pérez-Cruz, F.; Serra, S.; Delogu, G.; Lapier, M.; Maya, J.D.; Olea-Azar, C.; Santana, L.; Uriarte, E.. "Antitrypanosomal and antioxidant properties of 4-hydroxycoumarins derivatives". Bioorganic and Medicinal Chemistry Letters 22 17 (2012): 5569-5573. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865145129&partnerID=MN8TOARS.
    10.1016/j.bmcl.2012.07.013
  123. Dalla Via, L.; Gia, O.; Caffieri, S.; García-Argáez, A.N.; Quezada, E.; Uriarte, E.. "A novel tetrahydrobenzoangelicin with dark and photo biological activity". Bioorganic and Medicinal Chemistry 20 11 (2012): 3603-3608. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861193868&partnerID=MN8TOARS.
    10.1016/j.bmc.2012.03.071
  124. Matos, M.J.; Santana, L.; Uriarte, E.; Serra, S.; Corda, M.; Fadda, M.B.; Era, B.; Fais, A.. "Tyrosine-like condensed derivatives as tyrosinase inhibitors". Journal of Pharmacy and Pharmacology 64 5 (2012): 742-746. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859616269&partnerID=MN8TOARS.
    10.1111/j.2042-7158.2012.01467.x
  125. Vilar, S.; Harpaz, R.; Santana, L.; Uriarte, E.; Friedman, C.. "Enhancing adverse drug event detection in electronic health records using molecular structure similarity: Application to pancreatitis". PLoS ONE 7 7 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84864204553&partnerID=MN8TOARS.
    10.1371/journal.pone.0041471
  126. Gaspar, A.; Reis, J.; Kachler, S.; Paoletta, S.; Uriarte, E.; Klotz, K.-N.; Moro, S.; Borges, F.. "Discovery of novel A 3 adenosine receptor ligands based on chromone scaffold". Biochemical Pharmacology 84 1 (2012): 21-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860664996&partnerID=MN8TOARS.
    10.1016/j.bcp.2012.03.007
  127. Viña, D.; Matos, M.J.; Yáñez, M.; Santana, L.; Uriarte, E.. "3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease". MedChemComm 3 2 (2012): 213-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857253918&partnerID=MN8TOARS.
    10.1039/c1md00221j
  128. Serra, S.; Ferino, G.; Matos, M.J.; Vázquez-Rodríguez, S.; Delogu, G.; Viña, D.; Cadoni, E.; Santana, L.; Uriarte, E.. "Hydroxycoumarins as selective MAO-B inhibitors". Bioorganic and Medicinal Chemistry Letters 22 1 (2012): 258-261. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655170309&partnerID=MN8TOARS.
    10.1016/j.bmcl.2011.11.020
  129. Viña, D.; Matos, M.J.; Ferino, G.; Cadoni, E.; Laguna, R.; Borges, F.; Uriarte, E.; Santana, L.. "8-Substituted 3-Arylcoumarins as Potent and Selective MAO-B Inhibitors: Synthesis, Pharmacological Evaluation, and Docking Studies". ChemMedChem 7 3 (2012): 464-470. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857718412&partnerID=MN8TOARS.
    10.1002/cmdc.201100538
  130. Yordi, E.G.; Molina Pérez, E.; Joao Matos, M.; Uriarte Villares, E.. "Structural alerts for predicting clastogenic activity of pro-oxidant flavonoid compounds: Quantitative structure-activity relationship study". Journal of Biomolecular Screening 17 2 (2012): 216-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856277168&partnerID=MN8TOARS.
    10.1177/1087057111421623
  131. Ferino G; Vilar S; Matos MJ; Uriarte E; Cadoni E; Ferino, G.; Vilar, S.; et al. "Monoamine oxidase inhibitors: ten years of docking studies.". Current Topics in Medicinal Chemistry 12 20 (2012): 2145-2162. http://europepmc.org/abstract/med/23231393.
    10.2174/156802612805220048
  132. Gaspar, A.; Silva, T.; Yáñez, M.; Vina, D.; Orallo, F.; Ortuso, F.; Uriarte, E.; Alcaro, S.; Borges, F.. "Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors". Journal of Medicinal Chemistry 54 14 (2011): 5165-5173. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960651250&partnerID=MN8TOARS.
    10.1021/jm2004267
  133. Matos, M.J.; Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L.; Viña, D.. "MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins". Bioorganic and Medicinal Chemistry Letters 21 14 (2011): 4224-4227. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959884460&partnerID=MN8TOARS.
    10.1016/j.bmcl.2011.05.074
  134. Matos, M.J.; Terán, C.; Pérez-Castillo, Y.; Uriarte, E.; Santana, L.; Viña, D.. "Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors". Journal of Medicinal Chemistry 54 20 (2011): 7127-7137. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054908624&partnerID=MN8TOARS.
    10.1021/jm200716y
  135. Gaspar, A.; Teixeira, F.; Uriarte, E.; Milhazes, N.; Melo, A.; Cordeiro, M.N.D.S.; Ortuso, F.; Alcaro, S.; Borges, F.. "Towards the Discovery of a Novel Class of Monoamine Oxidase Inhibitors: Structure-Property-Activity and Docking Studies on Chromone Amides". ChemMedChem 6 4 (2011): 628-632. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953066953&partnerID=MN8TOARS.
    10.1002/cmdc.201000452
  136. Delogu, G.; Picciau, C.; Ferino, G.; Quezada, E.; Podda, G.; Uriarte, E.; Viña, D.. "Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives". European Journal of Medicinal Chemistry 46 4 (2011): 1147-1152. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952282900&partnerID=MN8TOARS.
    10.1016/j.ejmech.2011.01.033
  137. Matos, M.J.; Santana, L.; Uriarte, E.; Delogu, G.; Corda, M.; Fadda, M.B.; Era, B.; et al. "New halogenated phenylcoumarins as tyrosinase inhibitors". Bioorganic and Medicinal Chemistry Letters 21 11 (2011): 3342-3345. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956100956&partnerID=MN8TOARS.
    10.1016/j.bmcl.2011.04.012
  138. Marzaro, G.; Chilin, A.; Guiotto, A.; Uriarte, E.; Brun, P.; Castagliuolo, I.; Tonus, F.; González-Díaz, H.. "Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors". European Journal of Medicinal Chemistry 46 6 (2011): 2185-2192. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955637731&partnerID=MN8TOARS.
    10.1016/j.ejmech.2011.02.072
  139. Gaspar, A.; Reis, J.; Fonseca, A.; Milhazes, N.; Viña, D.; Uriarte, E.; Borges, F.. "Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors". Bioorganic and Medicinal Chemistry Letters 21 2 (2011): 707-709. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651257725&partnerID=MN8TOARS.
    10.1016/j.bmcl.2010.11.128
  140. Speck-Planche, A.; Guilarte-Montero, L.; Yera-Bueno, R.; Rojas-Vargas, J.A.; García-López, A.; Uriarte, E.; Molina-Pérez, E.. "Rational design of new agrochemical fungicides using substructural descriptors". Pest Management Science 67 4 (2011): 438-445. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952600178&partnerID=MN8TOARS.
    10.1002/ps.2082
  141. Matos, M.J.; Vazquez-Rodriguez, S.; Borges, F.; Santana, L.; Uriarte, E.. "Synthesis of 3-arylcoumarins via Suzuki-cross-coupling reactions of 3-chlorocoumarin". Tetrahedron Letters 52 11 (2011): 1225-1227. http://www.scopus.com/inward/record.url?eid=2-s2.0-79751532872&partnerID=MN8TOARS.
    10.1016/j.tetlet.2011.01.048
  142. Alcaro, S.; Gaspar, A.; Ortuso, F.; Milhazes, N.; Orallo, F.; Uriarte, E.; Yáñez, M.; Borges, F.. "Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B". Bioorganic and Medicinal Chemistry Letters 20 9 (2010): 2709-2712. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950954802&partnerID=MN8TOARS.
    10.1016/j.bmcl.2010.03.081
  143. Planche, A.S.; Scotti, M.T.; De Emerenciano, V.P.; López, A.G.; Pérez, E.M.; Uriarte, E.. "Designing novel antitrypanosomal agents from a mixed graph-theoretical substructural approach". Journal of Computational Chemistry 31 4 (2010): 882-894. http://www.scopus.com/inward/record.url?eid=2-s2.0-76249132000&partnerID=MN8TOARS.
    10.1002/jcc.21374
  144. Dalla Via, L.; Gia, O.; Marciani Magno, S.; Braga, A.; González-Gómez, J.C.; Pérez-Montoto, L.G.; Uriarte, E.. "Pyridazinopsoralens of wide chemotherapeutic interest". Bioorganic and Medicinal Chemistry 18 15 (2010): 5708-5714. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955416799&partnerID=MN8TOARS.
    10.1016/j.bmc.2010.06.006
  145. Sobarzo-Sánchez, E.; Uriarte, E.; Santana, L.; Tapia, R.A.; Lourido, P.P.. "New approaches to 6-oxoisoaporphine and tetrahydroisoquinoline derivatives". Helvetica Chimica Acta 93 7 (2010): 1385-1394. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954911252&partnerID=MN8TOARS.
    10.1002/hlca.200900394
  146. Quezada, E.; Viña, D.; Delogu, G.; Borges, F.; Santana, L.; Uriarte, E.. "Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction: O2- vs. N1-alkylation". Helvetica Chimica Acta 93 2 (2010): 309-313. http://www.scopus.com/inward/record.url?eid=2-s2.0-76649117736&partnerID=MN8TOARS.
    10.1002/hlca.200900242
  147. Matos, M.J.; Delogu, G.; Podda, G.; Santana, L.; Uriarte, E.. "Regioselective synthesis of bromo-substituted 3-arylcoumarins". Synthesis 16 (2010): 2763-2766. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955398573&partnerID=MN8TOARS.
    10.1055/s-0029-1218835
  148. Estrada, E.; Molina, E.; Nodarse, D.; Uriarte, E.. "Structural contributions of substrates to their binding to P-glycoprotein. A TOPSMODE approach". Current Pharmaceutical Design 16 24 (2010): 2676-2709. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957964586&partnerID=MN8TOARS.
    10.2174/138161210792389243
  149. Perez-Bello, A.; Munteanu, C.R.; Ubeira, F.M.; Lopes De Magalhães, A.; Uriarte, E.; González-Díaz, H.. "Alignment-free prediction of mycobacterial DNA promoters based on pseudo-folding lattice network or star-graph topological indices". Journal of Theoretical Biology 256 3 (2009): 458-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149187912&partnerID=MN8TOARS.
    10.1016/j.jtbi.2008.09.035
  150. Prado-Prado, F.J.; de la Vega, O.M.; Uriarte, E.; Ubeira, F.M.; Chou, K.-C.; González-Díaz, H.. "Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks". Bioorganic and Medicinal Chemistry 17 2 (2009): 569-575. http://www.scopus.com/inward/record.url?eid=2-s2.0-58749107670&partnerID=MN8TOARS.
    10.1016/j.bmc.2008.11.075
  151. Agüero-Chapin, G.; Varona-Santos, J.; De La Riva, G.A.; Antunes, A.; González-Villa, T.; Uriarte, E.; González-Díaz, H.. "Alignment-free prediction of polygalacturonases with pseudofolding topological indices: Experimental isolation from coffea arabica and prediction of a new sequence". Journal of Proteome Research 8 4 (2009): 2122-2128. http://www.scopus.com/inward/record.url?eid=2-s2.0-65249098338&partnerID=MN8TOARS.
    10.1021/pr800867y
  152. Munteanu, C.R.; Magalhães, A.L.; Uriarte, E.; González-Díaz, H.. "Multi-target QPDR classification model for human breast and colon cancer-related proteins using star graph topological indices". Journal of Theoretical Biology 257 2 (2009): 303-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749111710&partnerID=MN8TOARS.
    10.1016/j.jtbi.2008.11.017
  153. García, I.; Munteanu, C.R.; Fall, Y.; Gómez, G.; Uriarte, E.; González-Díaz, H.. "QSAR and complex network study of the chiral HMGR inhibitor structural diversity". Bioorganic and Medicinal Chemistry 17 1 (2009): 165-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-57749180853&partnerID=MN8TOARS.
    10.1016/j.bmc.2008.11.007
  154. Concu, R.; Dea-Ayuela, M.A.; Perez-Montoto, L.G.; Prado-Prado, F.J.; Uriarte, E.; Bolás-Fernández, F.; Podda, G.; et al. "3D entropy and moments prediction of enzyme classes and experimental-theoretic study of peptide fingerprints in Leishmania parasites". Biochimica et Biophysica Acta - Proteins and Proteomics 1794 12 (2009): 1784-1794. http://www.scopus.com/inward/record.url?eid=2-s2.0-72449156778&partnerID=MN8TOARS.
    10.1016/j.bbapap.2009.08.020
  155. Prado-Prado, F.J.; Uriarte, E.; Borges, F.; González-Díaz, H.. "Multi-target spectral moments for QSAR and Complex Networks study of antibacterial drugs". European Journal of Medicinal Chemistry 44 11 (2009): 4516-4521. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349766733&partnerID=MN8TOARS.
    10.1016/j.ejmech.2009.06.018
  156. Vilar, S.; González-Díaz, H.; Santana, L.; Uriarte, E.. "A network-QSAR model for prediction of genetic-component biomarkers in human colorectal cancer". Journal of Theoretical Biology 261 3 (2009): 449-458. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350187090&partnerID=MN8TOARS.
    10.1016/j.jtbi.2009.07.031
  157. Prado-Prado, F.J.; Borges, F.; Uriarte, E.; Peréz-Montoto, L.G.; González-Díaz, H.. "Multi-target spectral moment: QSAR for antiviral drugs vs. different viral species". Analytica Chimica Acta 651 2 (2009): 159-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349274100&partnerID=MN8TOARS.
    10.1016/j.aca.2009.08.022
  158. Matos, M.J.; Viña, D.; Picciau, C.; Orallo, F.; Santana, L.; Uriarte, E.. "Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors". Bioorganic and Medicinal Chemistry Letters 19 17 (2009): 5053-5055. http://www.scopus.com/inward/record.url?eid=2-s2.0-68349155549&partnerID=MN8TOARS.
    10.1016/j.bmcl.2009.07.039
  159. Planche, A.S.; Scotti, M.T.; López, A.G.; De Paulo Emerenciano, V.; Pérez, E.M.; Uriarte, E.. "Design of novel antituberculosis compounds using graph-theoretical and substructural approaches". Molecular Diversity 13 4 (2009): 445-458. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349904699&partnerID=MN8TOARS.
    10.1007/s11030-009-9129-9
  160. Concu, R.; Dea-Ayuela, M.A.; Perez-Montoto, L.G.; Bolas-Fernández, F.; Prado-Prado, F.J.; Podda, G.; Uriarte, E.; Ubeira, F.M.; González-Díaz, H.. "Prediction of enzyme classes from 3D structure: A general model and examples of experimental-theoretic scoring of peptide mass fingerprints of Leishmania proteins". Journal of Proteome Research 8 9 (2009): 4372-4382. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349895744&partnerID=MN8TOARS.
    10.1021/pr9003163
  161. Viña, D.; Uriarte, E.; Orallo, F.; González-Díaz, H.. "Alignment-free prediction of a drug-target complex network based on parameters of drug connectivity and protein sequence of receptors". Molecular Pharmaceutics 6 3 (2009): 825-835. http://www.scopus.com/inward/record.url?eid=2-s2.0-67249095008&partnerID=MN8TOARS.
    10.1021/mp800102c
  162. Dalla Via, L.; González-Gómez, J.C.; Pérez-Montoto, L.G.; Santana, L.; Uriarte, E.; Marciani Magno, S.; Gia, O.. "A new psoralen derivative with enlarged antiproliferative properties". Bioorganic and Medicinal Chemistry Letters 19 10 (2009): 2874-2876. http://www.scopus.com/inward/record.url?eid=2-s2.0-65349140777&partnerID=MN8TOARS.
    10.1016/j.bmcl.2009.03.073
  163. Concu, R.; Podda, G.; Uriarte, E.; González-Díaz, H.. "Computational chemistry study of 3D-structure-function relationships for enzymes based on markov models for protein electrostatic, HINT, and van der waals potentials". Journal of Computational Chemistry 30 9 (2009): 1510-1520. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650113056&partnerID=MN8TOARS.
    10.1002/jcc.21170
  164. Matos, M.J.; Viña, D.; Quezada, E.; Picciau, C.; Delogu, G.; Orallo, F.; Santana, L.; Uriarte, E.. "A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors". Bioorganic and Medicinal Chemistry Letters 19 12 (2009): 3268-3270. http://www.scopus.com/inward/record.url?eid=2-s2.0-65749116833&partnerID=MN8TOARS.
    10.1016/j.bmcl.2009.04.085
  165. Vilar, S.; González-Díaz, H.; Santana, L.; Uriarte, E.. "QSAR model for alignment-free prediction of human breast cancer biomarkers based on electrostatic potentials of protein pseudofolding HP-lattice networks". Journal of Computational Chemistry 29 16 (2008): 2613-2622. http://www.scopus.com/inward/record.url?eid=2-s2.0-57049145806&partnerID=MN8TOARS.
    10.1002/jcc.21016
  166. Cruz-Monteagudo, M.; Munteanu, C.R.; Borges, F.; Cordeiro, M.N.D.S.; Uriarte, E.; Chou, K.-C.; González-Díaz, H.. "Stochastic molecular descriptors for polymers. 4. Study of complex mixtures with topological indices of mass spectra spiral and star networks: The blood proteome case". Polymer 49 25 (2008): 5575-5587. http://www.scopus.com/inward/record.url?eid=2-s2.0-56149097042&partnerID=MN8TOARS.
    10.1016/j.polymer.2008.09.070
  167. González-Díaz, H.; Cabrera-Pérez, M.A.; Agüero-Chapín, G.; Cruz-Monteagudo, M.; Castañeda-Cancio, N.; del Río, M.A.; Uriarte, E.. "Multi-target QSPR assemble of a Complex Network for the distribution of chemicals to biphasic systems and biological tissues". Chemometrics and Intelligent Laboratory Systems 94 2 (2008): 160-165. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349164135&partnerID=MN8TOARS.
    10.1016/j.chemolab.2008.07.006
  168. Ferino, G.; González-Díaz, H.; Delogu, G.; Podda, G.; Uriarte, E.. "Using spectral moments of spiral networks based on PSA/mass spectra outcomes to derive quantitative proteome-disease relationships (QPDRs) and predicting prostate cancer". Biochemical and Biophysical Research Communications 372 2 (2008): 320-325. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649104406&partnerID=MN8TOARS.
    10.1016/j.bbrc.2008.05.071
  169. Quezada, E.; Delogu, G.; Viña, D.; Santana, L.; Picciau, C.; Podda, G.; Uriarte, E.. "Synthesis and complete assignment of the 1H and 13C NMR signals of some oxopyrancoumarin and oxofuropyrancoumarin derivatives". Magnetic Resonance in Chemistry 46 7 (2008): 701-705. http://www.scopus.com/inward/record.url?eid=2-s2.0-48549103276&partnerID=MN8TOARS.
    10.1002/mrc.2223
  170. Cruz-Monteagudo, M.; Munteanu, C.R.; Borges, F.; Cordeiro, M.N.D.S.; Uriarte, E.; González-Díaz, H.. "Quantitative Proteome-Property Relationships (QPPRs). Part 1: Finding biomarkers of organic drugs with mean Markov connectivity indices of spiral networks of blood mass spectra". Bioorganic and Medicinal Chemistry 16 22 (2008): 9684-9693. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949158392&partnerID=MN8TOARS.
    10.1016/j.bmc.2008.10.004
  171. Santana, L.; González-Díaz, H.; Quezada, E.; Uriarte, E.; Yáñez, M.; Viña, D.; Orallo, F.. "Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors". Journal of Medicinal Chemistry 51 21 (2008): 6740-6751. http://www.scopus.com/inward/record.url?eid=2-s2.0-56249083925&partnerID=MN8TOARS.
    10.1021/jm800656v
  172. Chilin, A.; Battistutta, R.; Bortolato, A.; Cozza, G.; Zanatta, S.; Poletto, G.; Mazzorana, M.; et al. "Coumarin as attractive Casein Kinase 2 (CK2) inhibitor scaffold: An integrate approach to elucidate the putative binding motif and explain structure-activity relationships". Journal of Medicinal Chemistry 51 4 (2008): 752-759. http://www.scopus.com/inward/record.url?eid=2-s2.0-39749107915&partnerID=MN8TOARS.
    10.1021/jm070909t
  173. González-Díaz, H.; González-Díaz, Y.; Santana, L.; Ubeira, F.M.; Uriarte, E.. "Proteomics, networks and connectivity indices". Proteomics 8 4 (2008): 750-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-40549136471&partnerID=MN8TOARS.
    10.1002/pmic.200700638
  174. Molina, E.; Estrada, E.; Nodarse, D.; Torres, L.A.; González, H.; Uriarte, E.. "Quantitative structure-antibacterial activity relationship modeling using a combination of piecewise linear regression-discriminant analysis (I): Quantum chemical, topographic, and topological descriptors". International Journal of Quantum Chemistry 108 10 (2008): 1856-1871. http://www.scopus.com/inward/record.url?eid=2-s2.0-45749127483&partnerID=MN8TOARS.
    10.1002/qua.21702
  175. Diniz, C.; Borges, F.; Santana, L.; Uriarte, E.; Oliveira, J.M.A.; Gonçalves, J.; Fresco, P.. "Ligands and therapeutic perspectives of adenosine A2A receptors". Current Pharmaceutical Design 14 17 (2008): 1698-1722. http://www.scopus.com/inward/record.url?eid=2-s2.0-47349120493&partnerID=MN8TOARS.
    10.2174/138161208784746842
  176. Patlewicz, G.; Roberts, D.W.; Uriarte, E.. "A comparison of reactivity schemes for the prediction skin sensitization potential". Chemical Research in Toxicology 21 2 (2008): 521-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-41649099510&partnerID=MN8TOARS.
    10.1021/tx700338q
  177. Patlewicz, G.; Aptula, A.O.; Roberts, D.W.; Uriarte, E.. "A minireview of available skin sensitization (Q)SARs/expert systems". QSAR and Combinatorial Science 27 1 (2008): 60-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849134167&partnerID=MN8TOARS.
    10.1002/qsar.200710067
  178. Quezada, E.; Vilar, S.; Viña, D.; Santana, L.; Uriarte, E.. "Assignment of the 1H and 13C NMR signals of some hydroxyphenylcoumarins". Magnetic Resonance in Chemistry 45 1 (2007): 99-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845961054&partnerID=MN8TOARS.
    10.1002/mrc.1924
  179. Prado-Prado, F.J.; González-Díaz, H.; Santana, L.; Uriarte, E.. "Unified QSAR approach to antimicrobials. Part 2: Predicting activity against more than 90 different species in order to halt antibacterial resistance". Bioorganic and Medicinal Chemistry 15 2 (2007): 897-902. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845316136&partnerID=MN8TOARS.
    10.1016/j.bmc.2006.10.039
  180. González-Díaz, H.; Olazábal, E.; Santana, L.; Uriarte, E.; González-Díaz, Y.; Castañedo, N.. "QSAR study of anticoccidial activity for diverse chemical compounds: Prediction and experimental assay of trans-2-(2-nitrovinyl)furan". Bioorganic and Medicinal Chemistry 15 2 (2007): 962-968. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845283571&partnerID=MN8TOARS.
    10.1016/j.bmc.2006.10.032
  181. González-Díaz, H.; Pérez-Castillo, Y.; Podda, G.; Uriarte, E.. "Computational chemistry comparison of stable/nonstable protein mutants classification models based on 3d and topological indices". Journal of Computational Chemistry 28 12 (2007): 1990-1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547347534&partnerID=MN8TOARS.
    10.1002/jcc.20700
  182. Cruz-Monteagudo, M.; González-Díaz, H.; Agüero-CHAPÍN, G.; Santana, L.; Borges, F.; Domínguez, E.R.; Podda, G.; Uriarte, E.. "Computational chemistry development of a unified free energy Markov Model for the distribution of 1300 chemicals to 38 different environmental or biological systems". Journal of Computational Chemistry 28 11 (2007): 1909-1923. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547364589&partnerID=MN8TOARS.
    10.1002/jcc.20730
  183. Milhazes, N.; Martins, P.; Uriarte, E.; Garrido, J.; Calheiros, R.; Marques, M.P.M.; Borges, F.. "Electrochemical and spectroscopic characterisation of amphetamine-like drugs: Application to the screening of 3,4-methylenedioxymethamphetamine (MDMA) and its synthetic precursors". Analytica Chimica Acta 596 2 (2007): 231-241. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447260978&partnerID=MN8TOARS.
    10.1016/j.aca.2007.06.027
  184. Patlewicz, G.; Aptula, A.O.; Uriarte, E.; Roberts, D.W.; Kern, P.S.; Gerberick, G.F.; Kimber, I.; et al. "An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential". SAR and QSAR in Environmental Research 18 5-6 (2007): 515-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547500757&partnerID=MN8TOARS.
    10.1080/10629360701427872
  185. Estrada, E.; Uriarte, E.. "Erratum to "Folding degrees of azurins and pseudoazurins. Implications for structure and function" [Comput. Biol. Chem. 29 (2005) 345-353] (DOI:10.1016/j.compbiolchem.2005.06.005)". Computational Biology and Chemistry 31 4 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-34447643951&partnerID=MN8TOARS.
    10.1016/j.compbiolchem.2007.05.005
  186. Delogu, G.; Picciau, C.; Quezada, E.; Santana, L.; Uriarte, E.. "Divergent synthesis of linear and angular furocoumarin acetic acids from phloroglucinol". Synlett 12 (2007): 1951-1953. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547617918&partnerID=MN8TOARS.
    10.1055/s-2007-984536
  187. González-Díaz, H.; Vilar, S.; Santana, L.; Uriarte, E.. "Medicinal chemistry and bioinformatics - Current trends in drugs discovery with networks topological indices". Current Topics in Medicinal Chemistry 7 10 (2007): 1015-1029. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447254270&partnerID=MN8TOARS.
    10.2174/156802607780906771
  188. González-Díaz, H.; Agüero-Chapin, G.; Varona, J.; Molina, R.; Delogu, G.; Santana, L.; Uriarte, E.; Podda, G.. "2D-RNA-coupling numbers: A new computational chemistry approach to link secondary structure topology with biological function". Journal of Computational Chemistry 28 6 (2007): 1049-1056. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947725480&partnerID=MN8TOARS.
    10.1002/jcc.20576
  189. Estrada, E.; Uriarte, E.; Vilar, S.. "Erratum: Effect of protein folding on the stability of protein-ligand complexes (Journal of Proteome Research (2006) 5 (105-111))". Journal of Proteome Research 6 7 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-34547222495&partnerID=MN8TOARS.
    10.1021/pr0702870
  190. González-Díaz, H.; Bonet, I.; Terán, C.; De Clercq, E.; Bello, R.; García, M.M.; Santana, L.; Uriarte, E.. "ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds". European Journal of Medicinal Chemistry 42 5 (2007): 580-585. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248201649&partnerID=MN8TOARS.
    10.1016/j.ejmech.2006.11.016
  191. González-Díaz, H.; Saiz-Urra, L.; Molina, R.; Santana, L.; Uriarte, E.. "A model for the recognition of protein kinases based on the entropy of 3D van der waals interactions". Journal of Proteome Research 6 2 (2007): 904-908. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847420914&partnerID=MN8TOARS.
    10.1021/pr060493s
  192. González-Díaz, H.; Pérez-Bello, A.; Cruz-Monteagudo, M.; González-Díaz, Y.; Santana, L.; Uriarte, E.. "Chemometrics for QSAR with low sequence homology: Mycobacterial promoter sequences recognition with 2D-RNA entropies". Chemometrics and Intelligent Laboratory Systems 85 1 (2007): 20-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845662803&partnerID=MN8TOARS.
    10.1016/j.chemolab.2006.03.005
  193. González-Díaz, H.; Vilar, S.; Santana, L.; Podda, G.; Uriarte, E.. "On the applicability of QSAR for recognition of miRNA bioorganic structures at early stages of organism and cell development: Embryo and stem cells". Bioorganic and Medicinal Chemistry 15 7 (2007): 2544-2550. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847675464&partnerID=MN8TOARS.
    10.1016/j.bmc.2007.01.050
  194. Vilar, S.; Quezada, E.; Alcaide, C.; Orallo, F.; Santana, L.; Uriarte, E.. "Quantitative structure vasodilatory activity relationship - Synthesis and "in silico" and "in vitro" evaluation of resveratrol-coumarin hybrids". QSAR and Combinatorial Science 26 3 (2007): 317-332. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250675344&partnerID=MN8TOARS.
    10.1002/qsar.200630006
  195. Vilar, S.; Quezada, E.; Santana, L.; Uriarte, E.; Yánez, M.; Fraiz, N.; Alcaide, C.; Cano, E.; Orallo, F.. "Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids". Bioorganic and Medicinal Chemistry Letters 16 2 (2006): 257-261. http://www.scopus.com/inward/record.url?eid=2-s2.0-27944434132&partnerID=MN8TOARS.
    10.1016/j.bmcl.2005.10.013
  196. Estrada, E.; Uriarte, E.; Vilar, S.. "Effect of protein backbone folding on the stability of protein-ligand complexes". Journal of Proteome Research 5 1 (2006): 105-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-30744442311&partnerID=MN8TOARS.
    10.1021/pr0503174
  197. Agüero-Chapin, G.; González-Díaz, H.; Molina, R.; Varona-Santos, J.; Uriarte, E.; González-Díaz, Y.. "Novel 2D maps and coupling numbers for protein sequences. The first QSAR study of polygalacturonases; isolation and prediction of a novel sequence from Psidium guajava L.". FEBS Letters 580 3 (2006): 723-730. http://www.scopus.com/inward/record.url?eid=2-s2.0-31444455638&partnerID=MN8TOARS.
    10.1016/j.febslet.2005.12.072
  198. González-Díaz, H.; Pérez-Bello, A.; Uriarte, E.; González-Díaz, Y.. "QSAR study for mycobacterial promoters with low sequence homology". Bioorganic and Medicinal Chemistry Letters 16 3 (2006): 547-553. http://www.scopus.com/inward/record.url?eid=2-s2.0-29544451730&partnerID=MN8TOARS.
    10.1016/j.bmcl.2005.10.057
  199. Estrada, E.; Uriarte, E.; Molina, E.; Simón-Manso, Y.; Milne, G.W.A.. "An integrated in silico analysis of drug-binding to human serum albumin". Journal of Chemical Information and Modeling 46 6 (2006): 2709-2724. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845733253&partnerID=MN8TOARS.
    10.1021/ci600274f
  200. Martinez-Bisbal, M.C.; Vilar, S.; Teijeira, M.; Celda, B.; Uriarte, E.; Santana, L.. "Synthesis and structural study of carbocyclic analogues of 1,2-disubstituted nucleosides". Structural Chemistry 17 5 (2006): 465-471. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845346493&partnerID=MN8TOARS.
    10.1007/s11224-006-9068-3
  201. Cruz-Monteagudo, M.; González-Díaz, H.; Uriarte, E.. "Simple stochastic fingerprints towards mathematical modeling in biology and medicine 2. Unifying Markov model for drugs side effects". Bulletin of Mathematical Biology 68 7 (2006): 1527-1554. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748705541&partnerID=MN8TOARS.
    10.1007/s11538-005-9013-4
  202. Viña, D.; Quezada, E.; Santana, L.; Uriarte, E.. "Regioselective synthesis of O2- and O6-cyclopyrimidine nucleoside analogues". Tetrahedron 62 42 (2006): 9949-9952. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748132157&partnerID=MN8TOARS.
    10.1016/j.tet.2006.08.007
  203. Canoa, P.; González-Moa, M.J.; Teijeira, M.; Terán, C.; Uriarte, E.; Pannecouque, C.; De Clercq, E.. "Synthesis and anti-HIV activity of novel cyclopentenyl nucleoside analogues of 8-azapurine". Chemical and Pharmaceutical Bulletin 54 10 (2006): 1418-1420. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749385788&partnerID=MN8TOARS.
    10.1248/cpb.54.1418
  204. Dalla Via, L.; Mammi, S.; Uriarte, E.; Santana, L.; Lampronti, I.; Gambari, R.; Gia, O.. "New furan side tetracyclic allopsoralen derivatives: Synthesis and photobiological evaluation". Journal of Medicinal Chemistry 49 14 (2006): 4317-4326. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745807609&partnerID=MN8TOARS.
    10.1021/jm058032q
  205. González-Moa, M.J.; Besada, P.; Terán, C.; Santana, L.; Uriarte, E.; Viña, D.. "Synthesis of 1,2-disubstituted carbocyclic nucleoside analogues of cytidine". Helvetica Chimica Acta 89 5 (2006): 954-961. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744948896&partnerID=MN8TOARS.
    10.1002/hlca.200690099
  206. Quezada, E.; Vilar, S.; Valencia, L.; Santana, L.; Mosquera, R.A.; Uriarte, E.. "3D comparative structural study of 6-hydroxy-4-methyl-5,7-dinitrocoumarin using experimental and theoretical approaches". Structural Chemistry 17 5 (2006): 459-464. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845289792&partnerID=MN8TOARS.
    10.1007/s11224-006-9097-y
  207. González-Díaz, H.; Prado-Prado, F.J.; Santana, L.; Uriarte, E.. "Unify QSAR approach to antimicrobials. Part 1: Predicting antifungal activity against different species". Bioorganic and Medicinal Chemistry 14 17 (2006): 5973-5980. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746075173&partnerID=MN8TOARS.
    10.1016/j.bmc.2006.05.018
  208. Vilar, S.; Santana, L.; Uriarte, E.. "Probabilistic neural network model for the in silico evaluation of anti-HIV activity and mechanism of action". Journal of Medicinal Chemistry 49 3 (2006): 1118-1124. http://www.scopus.com/inward/record.url?eid=2-s2.0-32344439358&partnerID=MN8TOARS.
    10.1021/jm050932j
  209. Santana, L.; Uriarte, E.; González-Díaz, H.; Zagotto, G.; Soto-Otero, R.; Méndez-Álvarez, E.. "A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins". Journal of Medicinal Chemistry 49 3 (2006): 1149-1156. http://www.scopus.com/inward/record.url?eid=2-s2.0-32344446616&partnerID=MN8TOARS.
    10.1021/jm0509849
  210. González-Díaz, H.; Viña, D.; Santana, L.; De Clercq, E.; Uriarte, E.. "Stochastic entropy QSAR for the in silico discovery of anticancer compounds: Prediction, synthesis, and in vitro assay of new purine carbanucleosides". Bioorganic and Medicinal Chemistry 14 4 (2006): 1095-1107. http://www.scopus.com/inward/record.url?eid=2-s2.0-30344455624&partnerID=MN8TOARS.
    10.1016/j.bmc.2005.09.039
  211. Vilar, S.; Estrada, E.; Uriarte, E.; Santana, L.; Gutierrez, Y.. "In silico studies toward the discovery of new anti-HIV nucleoside compounds through the use of tops-mode and 2D/3D connectivity indices. 2. Purine derivatives". Journal of Chemical Information and Modeling 45 2 (2005): 502-514. http://www.scopus.com/inward/record.url?eid=2-s2.0-18344374912&partnerID=MN8TOARS.
    10.1021/ci049662o
  212. González-Díaz, H.; Cruz-Monteagudo, M.; Molina, R.; Tenorio, E.; Uriarte, E.. "Predicting multiple drugs side effects with a general drug-target interaction thermodynamic Markov model". Bioorganic and Medicinal Chemistry 13 4 (2005): 1119-1129. http://www.scopus.com/inward/record.url?eid=2-s2.0-12844277442&partnerID=MN8TOARS.
    10.1016/j.bmc.2004.11.030
  213. González-Díaz, H.; Tenorio, E.; Castañedo, N.; Santana, L.; Uriarte, E.. "3D QSAR Markov model for drug-induced eosinophilia - Theoretical prediction and preliminary experimental assay of the antimicrobial drug G1". Bioorganic and Medicinal Chemistry 13 5 (2005): 1523-1530. http://www.scopus.com/inward/record.url?eid=2-s2.0-13444271897&partnerID=MN8TOARS.
    10.1016/j.bmc.2004.12.028
  214. González-Díaz, H.; Torres-Gómez, L.A.; Guevara, Y.; Almeida, M.S.; Molina, R.; Castañedo, N.; Santana, L.; Uriarte, E.. "Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design III: 2.5D indices for the discovery of antibacterials". Journal of Molecular Modeling 11 2 (2005): 116-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844496945&partnerID=MN8TOARS.
    10.1007/s00894-004-0228-3
  215. González-Díaz, H.; Uriarte, E.; Ramos De Armas, R.. "Predicting stability of Arc repressor mutants with protein stochastic moments". Bioorganic and Medicinal Chemistry 13 2 (2005): 323-331. http://www.scopus.com/inward/record.url?eid=2-s2.0-10444231203&partnerID=MN8TOARS.
    10.1016/j.bmc.2004.10.024
  216. Viña, D.; Santana, L.; Uriarte, E.; Terán, C.. "1,2-Disubstituted cyclohexane nucleosides: Comparative study for the synthesis of cis and trans adenosine analogues". Tetrahedron 61 2 (2005): 473-478. http://www.scopus.com/inward/record.url?eid=2-s2.0-9744244962&partnerID=MN8TOARS.
    10.1016/j.tet.2004.10.076
  217. González-Díaz, H.; Agüero, G.; Cabrera, M.A.; Molina, R.; Santana, L.; Uriarte, E.; Delogu, G.; Castañedo, N.. "Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species:: Distribution of the antimicrobial G1 on rat tissues". Bioorganic and Medicinal Chemistry Letters 15 3 (2005): 551-557. http://www.scopus.com/inward/record.url?eid=2-s2.0-12444269951&partnerID=MN8TOARS.
    10.1016/j.bmcl.2004.11.059
  218. Gia, O.; Marciani Magno, S.; Gonzalez-Diaz, H.; Quezada, E.; Santana, L.; Uriarte, E.; Dalla Via, L.. "Design, synthesis and photobiological properties of 3,4- cyclopentenepsoralens". Bioorganic and Medicinal Chemistry 13 3 (2005): 809-817. http://www.scopus.com/inward/record.url?eid=2-s2.0-11844285631&partnerID=MN8TOARS.
    10.1016/j.bmc.2004.10.044
  219. Galán, J.J.; González-Pérez, A.; Seijas, J.A.; Uriarte, E.; Rodríguez, J.R.. "Effect of counterion on thermodynamic micellar properties of tetradecylpyridinium in aqueous solutions". Colloid and Polymer Science 283 4 (2005): 456-460. http://www.scopus.com/inward/record.url?eid=2-s2.0-12144254609&partnerID=MN8TOARS.
    10.1007/s00396-004-1206-0
  220. González-Díaz, H.; Molina, R.; Uriarte, E.. "Recognition of stable protein mutants with 3D stochastic average electrostatic potentials". FEBS Letters 579 20 (2005): 4297-4301. http://www.scopus.com/inward/record.url?eid=2-s2.0-23644443075&partnerID=MN8TOARS.
    10.1016/j.febslet.2005.06.065
  221. González-Díaz, H.; Pérez-Bello, A.; Uriarte, E.. "Stochastic molecular descriptors for polymers. 3. Markov electrostatic moments as polymer 2D-folding descriptors: RNA-QSAR for mycobacterial promoters". Polymer 46 17 (2005): 6461-6473. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645291006&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.04.104
  222. González-Díaz, H.; Uriarte, E.. "Proteins QSAR with Markov average electrostatic potentials". Bioorganic and Medicinal Chemistry Letters 15 22 (2005): 5088-5094. http://www.scopus.com/inward/record.url?eid=2-s2.0-25844519060&partnerID=MN8TOARS.
    10.1016/j.bmcl.2005.07.056
  223. Estrada, E.; Uriarte, E.. "Folding degrees of azurins and pseudoazurins: Implications for structure and function". Computational Biology and Chemistry 29 5 (2005): 345-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-27644503774&partnerID=MN8TOARS.
    10.1016/j.compbiolchem.2005.06.005
  224. González-Gómez, J.C.; Santana, L.; Uriarte, E.. "A furan ring expansion approach to the synthesis of novel pyridazino-psoralen derivatives". Tetrahedron 61 20 (2005): 4805-4810. http://www.scopus.com/inward/record.url?eid=2-s2.0-17844396930&partnerID=MN8TOARS.
    10.1016/j.tet.2005.03.018
  225. Borges, F.; Roleira, F.; Milhazes, N.; Santana, L.; Uriarte, E.. "Simple coumarins and analogues in medicinal chemistry: Occurrence, synthesis and biological activity". Current Medicinal Chemistry 12 8 (2005): 887-916. http://www.scopus.com/inward/record.url?eid=2-s2.0-15944389028&partnerID=MN8TOARS.
    10.2174/0929867053507315
  226. González-Díaz, H.; Agüero-Chapin, G.; Varona-Santos, J.; Molina, R.; De La Riva, G.; Uriarte, E.. "2D RNA-QSAR: Assigning ACC oxidase family membership with stochastic molecular descriptors; isolation and prediction of a sequence from Psidium guajava L". Bioorganic and Medicinal Chemistry Letters 15 11 (2005): 2932-2937. http://www.scopus.com/inward/record.url?eid=2-s2.0-19544379174&partnerID=MN8TOARS.
    10.1016/j.bmcl.2005.03.017
  227. Saíz-Urra, L.; González-Díaz, H.; Uriarte, E.. "Proteins Markovian 3D-QSAR with spherically-truncated average electrostatic potentials". Bioorganic and Medicinal Chemistry 13 11 (2005): 3641-3647. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144386946&partnerID=MN8TOARS.
    10.1016/j.bmc.2005.03.041
  228. González-Díaz, H.; Saíz-Urra, L.; Molina, R.; Uriarte, E.. "Stochastic molecular descriptors for polymers. 2. Spherical truncation of electrostatic interactions on entropy based polymers 3D-QSAR". Polymer 46 8 (2005): 2791-2798. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844364760&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.01.066
  229. González-Díaz, H.; Cruz-Monteagudo, M.; Viña, D.; Santana, L.; Uriarte, E.; De Clercq, E.. "QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices". Bioorganic and Medicinal Chemistry Letters 15 6 (2005): 1651-1657. http://www.scopus.com/inward/record.url?eid=2-s2.0-14644425176&partnerID=MN8TOARS.
    10.1016/j.bmcl.2005.01.047
  230. González-Díaz, H.; Uriarte, E.. "Biopolymer stochastic moments. I. Modeling human rhinovirus cellular recognition with protein surface electrostatic moments". Biopolymers 77 5 (2005): 296-303. http://www.scopus.com/inward/record.url?eid=2-s2.0-17444397734&partnerID=MN8TOARS.
    10.1002/bip.20234
  231. Ramos De Armas, R.; González Díaz, H.; Molina, R.; Uriarte, E.. "Stochastic-based descriptors studying biopolymers biological properties: Extended MARCH-INSIDE methodology describing antibacterial activity of lactoferricin derivatives". Biopolymers 77 5 (2005): 247-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-17444377548&partnerID=MN8TOARS.
    10.1002/bip.20202
  232. Santana L; Uriarte E; Roleira F; Milhazes N; Borges F; Santana, L.; Uriarte, E.; et al. "Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity.". Current Medicinal Chemistry 11 24 (2004): 3239-3261. http://europepmc.org/abstract/med/15579011.
    10.2174/0929867043363721
  233. Viña, D.; Santana, L.; Uriarte, E.; Quezada, E.; Valencia, L.. "Synthesis of 1-[2-(hydroxymethyl)cyclohexyl]pyrimidine analogues of nucleosides: A comparative study". Synthesis 15 (2004): 2517-2522. http://www.scopus.com/inward/record.url?eid=2-s2.0-7644234690&partnerID=MN8TOARS.
    10.1055/s-2004-831224
  234. González-Díaz, H.; Molina, R.; Uriarte, E.. "Markov entropy backbone electrostatic descriptors for predicting proteins biological activity". Bioorganic and Medicinal Chemistry Letters 14 18 (2004): 4691-4695. http://www.scopus.com/inward/record.url?eid=2-s2.0-8544220400&partnerID=MN8TOARS.
    10.1016/j.bmcl.2004.06.100
  235. Begala M; González-Gómez JC; Podda G; Santana L; Tocco G; Uriarte E; Begala, M.; et al. "Characterisation of new pyridazinofurocoumarins by electron ionisation and multiple stage tandem mass spectrometry using an ion trap mass spectrometer.". Rapid Communications in Mass Spectrometry 18 5 (2004): 564-570. http://europepmc.org/abstract/med/14978801.
    10.1002/rcm.1363
  236. Molina E; Díaz HG; González MP; Rodríguez E; Uriarte E; Molina, E.; Díaz, H.G.; et al. "Designing antibacterial compounds through a topological substructural approach.". Journal of Chemical Information and Computer Sciences 44 2 (2004): 515-521. http://europepmc.org/abstract/med/15032531.
    10.1021/ci0342019
  237. Leiro, J.; Álvarez, E.; Arranz, J.A.; Laguna, R.; Uriarte, E.; Orallo, F.. "Effects of cis-resveratrol on inflammatory murine macrophages: Antioxidant activity and down-regulation of inflammatory genes". Journal of Leukocyte Biology 75 6 (2004): 1156-1165. http://www.scopus.com/inward/record.url?eid=2-s2.0-2642559707&partnerID=MN8TOARS.
    10.1189/jlb.1103561
  238. González Díaz, H.; Molina, R.; Uriarte, E.. "Stochastic molecular descriptors for polymers. 1. Modelling the properties of icosahedral viruses with 3D-Markovian negentropies". Polymer 45 11 (2004): 3845-3853. http://www.scopus.com/inward/record.url?eid=2-s2.0-2342498249&partnerID=MN8TOARS.
    10.1016/j.polymer.2004.03.071
  239. Ramos De Armas, R.; González Dí-az, H.; Molina, R.; Pérez González, M.; Uriarte, E.. "Stochastic-based descriptors studying peptides biological properties: Modeling the bitter tasting threshold of dipeptides". Bioorganic and Medicinal Chemistry 12 18 (2004): 4815-4822. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444320784&partnerID=MN8TOARS.
    10.1016/j.bmc.2004.07.017
  240. De Armas, R.R.; González Díaz, H.; Molina, R.; Uriarte, E.. "Markovian Backbone Negentropies: Molecular descriptors for protein research. I. Predicting protein stability in Arc repressor mutants". Proteins: Structure, Function and Genetics 56 4 (2004): 715-723. http://www.scopus.com/inward/record.url?eid=2-s2.0-4043133700&partnerID=MN8TOARS.
    10.1002/prot.20159
  241. Dalla Via, L.; Uriarte, E.; Santana, L.; Magno, S.M.; Gia, O.. "Methyl derivatives of tetracyclic psoralen analogues: Antiproliferative activity and interaction with DNA". Arkivoc 2004 5 (2004): 131-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942666302&partnerID=MN8TOARS.
  242. González-Moa, M.J.; Besada, P.; Teijeira, M.; Terán, C.; Uriarte, E.. "A short and convenient synthesis of new 1,2-disubstituted carbocyclic nucleoside analogues of pyrimidine based on a cyclopentene ring". Synthesis 4 (2004): 543-548. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144435108&partnerID=MN8TOARS.
  243. González-Gómez, J.C.; Santana, L.; Uriarte, E.; Brea, J.; Villazón, M.; Loza, M.I.; De Luca, M.; et al. "New arylpiperazine derivatives with high affinity for a1A, D2 and 5-HT2A receptors". Bioorganic and Medicinal Chemistry Letters 13 2 (2003): 175-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-17944395201&partnerID=MN8TOARS.
    10.1016/S0960-894X(02)00933-2
  244. González-Gómez, J.C.; Uriarte, E.. "Efficient Preparation of 2-Substituted Pyridazino[4,3-h]psoralen Derivatives". Synlett 14 (2003): 2225-2227. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242491558&partnerID=MN8TOARS.
  245. Begala, M.; Delogu, G.; Podda, G.; Gonzalez Gomez, J.C.; Santana, L.; Uriarte, E.. "Characterization of some isomeric furocoumarinones using gas chromatography ion trap tandem mass spectrometry". Spectroscopy Letters 36 4 (2003): 387-401. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141841685&partnerID=MN8TOARS.
    10.1081/SL-120024586
  246. Casellato, U.; Graziani, R.; Teijeira, M.; Uriarte, E.. "Crystal structure of {2-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl-methyl] cyclopentyl}-(4-fluorophenyl)-methanone, C24H27ClFNO 2". Zeitschrift fur Kristallographie - New Crystal Structures 218 4 (2003): 437-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748123608&partnerID=MN8TOARS.
  247. Gonzáles-Díaz, H.; Gia, O.; Uriarte, E.; Hernádez, I.; Ramos, R.; Chaviano, M.; Seijo, S.; et al. "Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design I: Discovery of anticancer compounds". Journal of Molecular Modeling 9 6 (2003): 395-407. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346670217&partnerID=MN8TOARS.
    10.1007/s00894-003-0148-7
  248. Terán, C.; Santana, L.; Uriarte, E.; Viña, D.; De Clercq, E.. "Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides". Nucleosides, Nucleotides and Nucleic Acids 22 5-8 (2003): 787-789. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141537140&partnerID=MN8TOARS.
    10.1081/NCN-120022635
  249. Via, L.D.; Uriarte, E.; Quezada, E.; Dolmella, A.; Ferlin, M.G.; Gia, O.. "Novel pyrone side tetracyclic psoralen derivatives: Synthesis and photobiological evaluation". Journal of Medicinal Chemistry 46 18 (2003): 3800-3810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042420821&partnerID=MN8TOARS.
    10.1021/jm0210919
  250. González-Gómez, J.C.; Santana, L.; Uriarte, E.. "Synthesis and convenient functionalisation of pyridazinofurocoumarins: Nitrogenated isosters of potent DNA inhibitors". Tetrahedron 59 41 (2003): 8171-8176. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141682321&partnerID=MN8TOARS.
    10.1016/j.tet.2003.08.051
  251. González Díaz, H.; Marrero, Y.; Hernández, I.; Bastida, I.; Tenorio, E.; Nasco, O.; Uriarte, E.; et al. "3D-MEDNEs: An Alternative "In Silico" Technique for Chemical Research in Toxicology. 1. Prediction of Chemically Induced Agranulocytosis". Chemical Research in Toxicology 16 10 (2003): 1318-1327. http://www.scopus.com/inward/record.url?eid=2-s2.0-10444249026&partnerID=MN8TOARS.
    10.1021/tx0256432
  252. Estrada, E.; Uriarte, E.; Gutierrez, Y.; González, H.. "Quantitative structure-toxicity relationships using TOPS-MODE. 3. Structural factors influencing the permeability of commercial solvents through living human skin". SAR and QSAR in Environmental Research 14 2 (2003): 145-163. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041402848&partnerID=MN8TOARS.
    10.1080/1062936031000073162
  253. González-Gómez, J.C.; Santana, L.; Uriarte, E.. "Regioselective synthesis of dihydrofuro[3,2-g]coumarin-6-one". Synthesis 1 (2003): 27-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037238449&partnerID=MN8TOARS.
  254. Díaz, H.G.; Sánchez, I.H.; Uriarte, E.; Santana, L.. "Symmetry considerations in Markovian chemicals 'in silico' design (MARCH-INSIDE) I: Central chirality codification, classification of ACE inhibitors and prediction of s-receptor antagonist activities". Computational Biology and Chemistry 27 3 (2003): 217-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042229159&partnerID=MN8TOARS.
    10.1016/S0097-8485(02)00053-0
  255. Estrada, E.; Patlewicz, G.; Uriarte, E.. "From molecular graphs to drugs. A review on the use of topological indices in drug design and discovery". Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry 42 6 (2003): 1315-1329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041559788&partnerID=MN8TOARS.
  256. Santana, L.; Teijeira, M.; Uriarte, E.; Balzarini, J.; De Clercq, E.. "Synthesis, conformational analysis and antiviral and antitumoral activity of new 1,2-disubstituted carbocyclic nucleosides". European Journal of Medicinal Chemistry 37 9 (2002): 755-760. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036753618&partnerID=MN8TOARS.
    10.1016/S0223-5234(02)01352-1
  257. Estrada, E.; Vilar, S.; Uriarte, E.; Gutierrez, Y.. "In silico studies toward the discovery of new anti-HIV nucleoside compounds with the use of TOPS-MODE and 2D/3D connectivity indices. 1. Pyrimidyl derivatives". Journal of Chemical Information and Computer Sciences 42 5 (2002): 1194-1203. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036708531&partnerID=MN8TOARS.
    10.1021/ci0255331
  258. González-Gómez, J.C.; Uriarte, E.. "A convenient preparation of 4-carboxamide derivatives of pyridazino [4,5-b]indoles and pyridazino[4,5-b]benzo[b]furans". Synlett 12 (2002): 2095-2097. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036458552&partnerID=MN8TOARS.
  259. González, J.C.; Lobo-Antunes, J.; Pérez-Lourido, P.; Santana, L.; Uriarte, E.. "Synthesis of angular pyrrolocoumarins". Synthesis 4 (2002): 475-478. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036199055&partnerID=MN8TOARS.
  260. Campos-Toimil, M.; Orallo, F.; Santana, L.; Uriarte, E.. "Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives". Bioorganic and Medicinal Chemistry Letters 12 5 (2002): 783-786. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037060914&partnerID=MN8TOARS.
    10.1016/S0960-894X(02)00015-X
  261. González-Gómez, J.C.; Uriarte-Villares, E.; Figueroa-Pérez, S.. "A cyclative cleavage approach to the solid phase synthesis of 2-oxo-1,4-piperazines". Synlett 7 (2002): 1085-1088. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036066524&partnerID=MN8TOARS.
  262. Santana, L.; Uriarte, E.; Fall, Y.; Teijeira, M.; Terán, C.; García-Martínez, E.; Tolf, B.-R.. "Synthesis and structure-activity relationships of new arylpiperazines: Para substitution with electron-withdrawing groups decrease binding to 5-HT1A and D2A receptors". European Journal of Medicinal Chemistry 37 6 (2002): 503-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036592242&partnerID=MN8TOARS.
    10.1016/S0223-5234(02)01357-0
  263. González-Gómez, J.C.; Santana, L.; Uriarte, E.. "Regioselective synthesis of linear and angular pyridazine furocoumarins". Synthesis 1 (2002): 43-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036137268&partnerID=MN8TOARS.
  264. Besada, P.; González-Moa, M.J.; Terán, C.; Santana, L.; Uriarte, E.. "Novel 1,2-disubstituted carbocyclic nucleoside analogues of purine with a cyclopentene ring". Synthesis 16 (2002): 2445-2449. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037923583&partnerID=MN8TOARS.
  265. Estrada E; Uriarte E. "Quantitative structure--toxicity relationships using TOPS-MODE. 1. Nitrobenzene toxicity to Tetrahymena pyriformis.". (2001): http://europepmc.org/abstract/med/11696927.
    10.1080/10629360108032919
  266. Estrada E; Molina E; Uriarte E. "Quantitative structure-toxicity relationships using TOPS-MODE. 2. Neurotoxicity of a non-congeneric series of solvents.". (2001): http://europepmc.org/abstract/med/11813810.
    10.1080/10629360108035384
  267. Fall, Y.; Santana, L.; Uriarte, E.. "Synthesis and characterization of some coumarins with two hydroxy or methoxy substituents". Journal of Heterocyclic Chemistry 38 5 (2001): 1231-1232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034749213&partnerID=MN8TOARS.
  268. Santana, L.; Teijeira, M.; Terán, C.; Uriarte, E.; Viña, D.. "Synthesis of 1,2-disubstituted carbocyclic analogs of pyrimidine and purine nucleosides". Synthesis 10 (2001): 1532-1538. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034919838&partnerID=MN8TOARS.
  269. Begala, M.; Delogu, G.; Maccioni, E.; Podda, G.; Tocco, G.; Quezada, E.; Uriarte, E.; et al. "Electrospray ionisation tandem mass spectrometry in the characterisation of isomeric benzofurocoumarins". Rapid Communications in Mass Spectrometry 15 12 (2001): 1000-1010. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034950947&partnerID=MN8TOARS.
    10.1002/rcm.331
  270. Estrada, E.; Uriarte, E.; Estrada E; Uriarte E. "Recent advances on the role of topological indices in drug discovery research". Current Medicinal Chemistry 8 13 (2001): 1573-1588. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035159445&partnerID=MN8TOARS.
    10.2174/0929867013371923
  271. Estrada, E.; Molina, E.; Uriarte, E.. "Quantitative structure-toxicity relationships using TOPS-MODE. 2. Neurotoxicity of a non-congeneric series of solvents.". SAR and QSAR in environmental research 12 5 (2001): 445-459. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035755060&partnerID=MN8TOARS.
  272. Viña, D.; Santana, L.; Uriarte, E.. "1,2-Disubstituted cyclohexane carbocyclic analogues of nucleosides". Nucleosides, Nucleotides and Nucleic Acids 20 4-7 (2001): 1363-1365. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034853647&partnerID=MN8TOARS.
    10.1081/NCN-100002556
  273. Besada, P.; Terán, C.; Quezada, E.; Seco, J.M.; Uriarte, E.. "Resolution of racemic mixtures of carbocyclic analogues of nucleosides and assignment of their absolute configuration". Nucleosides, Nucleotides and Nucleic Acids 20 4-7 (2001): 1359-1361. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034846046&partnerID=MN8TOARS.
    10.1081/NCN-100002555
  274. Estrada, E.; Uriarte, E.. "Quantitative structure--toxicity relationships using TOPS-MODE. 1. Nitrobenzene toxicity to Tetrahymena pyriformis.". SAR and QSAR in environmental research 12 3 (2001): 309-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035225894&partnerID=MN8TOARS.
  275. Quezada, E.; Santana, L.; Uriarte, E.. "Resolution of racemic carbonucleosides and assignment of the absolute configuration by NMR". Tetrahedron Asymmetry 12 19 (2001): 2637-2639. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035976091&partnerID=MN8TOARS.
    10.1016/S0957-4166(01)00470-0
  276. Teran C; Santana L; Teijeira M; Uriarte E; De Clercq E; Teran, C.; Santana, L.; et al. "Design, synthesis, conformational analysis and biological activities of purine-based 1,2-di-substituted carbocyclic nucleosides.". Chemical and Pharmaceutical Bulletin 48 2 (2000): 293-295. http://europepmc.org/abstract/med/10705524.
  277. Estrada, E.; González, J.C.; Santana, L.; Uriarte, E.; Castiñeiras, A.. "Synthesis, X-ray molecular structure, and semiempirical calculations of a new heteroarylpiperazine derivative". Structural Chemistry 11 4 (2000): 249-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034508648&partnerID=MN8TOARS.
    10.1023/A:1009214326827
  278. Santana, L.; Uriarte, E.; Dalla Via, L.; Gia, O.; Santana L; Uriarte E; Dalla Via L; Gia O. "A new benzoangelicin with strong photobiological activity". Bioorganic and Medicinal Chemistry Letters 10 2 (2000): 135-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034677022&partnerID=MN8TOARS.
    10.1016/S0960-894X(99)00640-X
  279. Estrada, E.; Uriarte, E.; Montero, A.; Teijeira, M.; Santana, L.; De Clercq, E.. "A novel approach for the virtual screening and rational design of anticancer compounds". Journal of Medicinal Chemistry 43 10 (2000): 1975-1985. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034038110&partnerID=MN8TOARS.
    10.1021/jm991172d
  280. Viola, G.; Uriarte, E.; Gia, O.; Moro, S.. "Interactions between DNA and benzo- and tetrahydrobenzofurocoumarins: Thermodynamic and molecular modeling studies". Farmaco 55 4 (2000): 276-286. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033846301&partnerID=MN8TOARS.
    10.1016/S0014-827X(00)00041-0
  281. Fall, Y.; Terán, C.; Teijeira, M.; Santana, L.; Uriarte, E.. "Synthesis of new 4-cyclohexylcoumarin derivatives". Synthesis 5 (2000): 643-645. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034035201&partnerID=MN8TOARS.
  282. Gonzalez, J.C.; Dedola, T.; Santana, L.; Uriarte, E.; Begala, M.; Copez, D.; Podda, G.. "Inverse electron demand Diels-Alder reactions of psoralens. Synthesis and mass spectra of novel pyridazinocoumarins". Journal of Heterocyclic Chemistry 37 4 (2000): 907-910. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033786420&partnerID=MN8TOARS.
  283. Dalla Via, L.; Gia, O.; Marciani Magno, S.; Santana, L.; Teijeira, M.; Uriarte, E.. "New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8- MOP: Synthesis, DNA interaction, and antiproliferative activity". Journal of Medicinal Chemistry 42 21 (1999): 4405-4413. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032741791&partnerID=MN8TOARS.
    10.1021/jm9910829
  284. Teijeira, M.; Terán, C.; Uriarte, E.. "Assignment of the 13C NMR signals of some 8-azaadenine, 2,6-diaminopurine and 2,6-diamino-8-azapurine carbonucleosides". Magnetic Resonance in Chemistry 37 8 (1999): 598-599. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033177322&partnerID=MN8TOARS.
  285. Santana, L.; Teijeira, M.; Uriarte, E.. "A slightly shorter route to carbocyclic nucleosides. Synthesis of (±)- trans-1-[2-(hydroxymethyl)cyclopentylmethyl]uracil". Journal of Heterocyclic Chemistry 36 1 (1999): 293-295. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032950817&partnerID=MN8TOARS.
  286. Besada, P.; Terán, C.; Santana, L.; Teijeira, M.; Uriarte, E.. "Nucleoside analogues of purine with a 1,2-disubstituted cyclopentene ring". Nucleosides and Nucleotides 18 4-5 (1999): 725-726. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033022012&partnerID=MN8TOARS.
  287. Santana, L.; Teijeira, M.; Uriarte, E.; Teran, C.; Liñares, B.; Villar, R.; Laguna, R.; Cano, E.. "AM1 theoretical study, synthesis and biological evaluation of some benzofuran analogues of anti-inflammatory arylalkanoic acids". European Journal of Pharmaceutical Sciences 7 2 (1999): 161-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032944624&partnerID=MN8TOARS.
    10.1016/S0928-0987(98)00019-0
  288. Zagotto, G.; Palumbo, M.; Uriarte, E.; Bonsignore, L.; Delogu, G.; Podda, G.. "Synthesis of 2H,9H-naphtho[2,3-b:7,6-b']dipyran-2,9-diones as potential DNA-reactive agents". Farmaco 53 10-11 (1998): 675-679. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032453581&partnerID=MN8TOARS.
    10.1016/S0014-827X(98)00085-8
  289. Dalla Via, L.; Gia, O.; Viola, G.; Bertoloni, G.; Santana, L.; Uriarte, E.. "Photobiological studies of new cyclopentene-psoralens". Farmaco 53 10-11 (1998): 638-644. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032463077&partnerID=MN8TOARS.
    10.1016/S0014-827X(98)00079-2
  290. Terán, C.; Santana, L.; Uriarte, E.; Fall, Y.; Unelius, L.; Tolf, B.-R.. "Phenylpiperazine derivatives with strong affinity for 5HT(1A), D(2A) and D3 receptors". Bioorganic and Medicinal Chemistry Letters 8 24 (1998): 3567-3570. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032535672&partnerID=MN8TOARS.
    10.1016/S0960-894X(98)00646-5
  291. Corda, L.; Delogu, G.; Favretto, D.; Maccioni, E.; Podda, G.; Santana, L.; Tomaselli, C.; Traldi, P.; Uriarte, E.. "Synthesis and mass spectrometric investigations of some new coumarin derivatives". Rapid Communications in Mass Spectrometry 12 24 (1998): 2041-2046. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032438694&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0231(19981230)12:24<2041::AID-RCM415>3.0.CO;2-0
  292. Santana, L.; Teijeira, M.; Uriarte, E.; Balzarini, J.; De Clercq, E.; Teijera, M.; Terán, C.; et al. "Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 2-amino-6-substituted purine and 8-azapurine". Bioorganic and Medicinal Chemistry Letters 8 11 (1998): 1349-1352. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032474494&partnerID=MN8TOARS.
    10.1016/S0960-894X(98)00216-9
  293. Orallo, F.; Lamela, M.; Camiña, M.; Uriarte, E.; Calleja, J.M.; Orallo F; Lamela M; et al. "Preliminary study of the potential vasodilator effects on rat aorta of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis". Planta Medica 64 2 (1998): 116-119. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031955470&partnerID=MN8TOARS.
  294. Teran, C.; Santana, L.; Teijeira, M.; Uriarte, E.; Balzarini, U.; De Clercq, E.; Terán C; et al. "Synthesis and chemotherapeutic activity of a carbocyclic analogue of tegafur". Pharmazie 53 9 (1998): http://www.scopus.com/inward/record.url?eid=2-s2.0-0031694514&partnerID=MN8TOARS.
  295. Terán, C.; Teijeira, M.; Santana, L.; Uriarte, E.; Castiñeiras, A.. "1-cyclopentyluracils: Synthesis and conformational analysis by X-ray crystallography and AM1 theoretical calculations". Journal of Molecular Structure 448 1 (1998): 69-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032490675&partnerID=MN8TOARS.
    10.1016/S0022-2860(98)00367-6
  296. Teijeira, M.; Santana, L.; Uriarte, E.. "Assignment of the 13C NMR spectra of some adenine, hypoxanthine and guanine carbonucleosides". Magnetic Resonance in Chemistry 35 11 (1997): 806-807. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031496019&partnerID=MN8TOARS.
  297. Gia O; Anselmo A; Pozzan A; Antonello C; Magno SM; Uriarte E; Gia, O.; et al. "Some new methyl-8-methoxypsoralens: synthesis, photobinding to DNA, photobiological properties and molecular modelling.". Farmaco 52 6-7 (1997): 389-397. http://europepmc.org/abstract/med/9372591.
  298. Fadda, A.M.; Podda, G.; Teijeira, M.; Uriarte, E.; Favretto, D.; D'Alpaos, M.; Traldi, P.; et al. "Synthesis and mass spectrometric behaviour of some new nucleosides as potential anti-HIV agents". Rapid Communications in Mass Spectrometry 11 7 (1997): 774-780. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030949327&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0231(19970422)11:7<774::AID-RCM906>3.0.CO;2-J
  299. Terán, C.; Miranda, R.; Santana, L.; Teijeira, M.; Uriarte, E.. "Synthesis of linear and angular benzofurocoumarins". Synthesis 12 (1997): 1384-1386. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031464458&partnerID=MN8TOARS.
  300. Jones, I.G.; Jones, W.; North, M.; Teijeira, M.; Uriarte, E.. "Desymmetrisation of bicyclic, meso-anhydrides by proline esters". Tetrahedron Letters 38 5 (1997): 889-892. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031016070&partnerID=MN8TOARS.
    10.1016/S0040-4039(96)02433-1
  301. Santana, L.; Teijeira, M.; Uriarte, E.; Terán, C.; Andrei, G.; Snoeck, R.; De Clercq, E.. "Synthesis and biological activity of some 2-aminopurine carbonucleosides". Nucleosides and Nucleotides 16 7-9 (1997): 1337-1339. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030734879&partnerID=MN8TOARS.
  302. Teijeira, M.; Uriarte, E.. "13C NMR spectral assignments of some cyclopentyluracils and 5-halouracils". Magnetic Resonance in Chemistry 35 5 (1997): 348-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031484394&partnerID=MN8TOARS.
  303. Zagotto, G.; Moro, S.; Uriarte, E.; Ferrazzi, E.; Palù, G.; Palumbo, M.; Zagotto G; et al. "Amido analogs of mitoxantrone: Physico-chemical properties, molecular modeling, cellular effects and antineoplastic potential". Anti-Cancer Drug Design 12 2 (1997): 99-112. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030893194&partnerID=MN8TOARS.
  304. Gia, O.; Conconi, M.T.; Uriarte, E.. "Benzo- and tetrahydrobenzo-furocoumarins: New potential photochemotherapeutic drugs". Farmaco 52 5 (1997): 289-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030857294&partnerID=MN8TOARS.
  305. Escuredo, V.; Ferro, B.; Santana, L.; Teijeira, M.; Uriarte, E.. "1,2-disubstituted carbocyclic analogues of thymine nucleosides". Nucleosides and Nucleotides 16 7-9 (1997): 1453-1456. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030782755&partnerID=MN8TOARS.
  306. Teijeira M; Santana L; Uriarte E; Jorge ML; Seoane R; Teijeira, M.; Santana, L.; et al. "Synthesis and cytostatic activity of some sulfamido-anthraquinones.". Farmaco 51 6 (1996): 447-450. http://europepmc.org/abstract/med/8766230.
  307. Santana L; Teijeira M; Uriarte E; Fadda A; Podda G; Catinella S; Traldi P; et al. "Electron impact mass spectrometry of some potential anti-HIV nucleosides.". Rapid communications in mass spectrometry : RCM 10 10 (1996): 1316-1319. http://europepmc.org/abstract/med/8759336.
    10.1002/(SICI)1097-0231(19960731)10:10<1316::AID-RCM617>3.0.CO;2-H
  308. Santana, L.; Teijeira, M.; Uriarte, E.; Teran, C.; Casellato, U.; Graziani, R.. "Synthesis of cis-1-(2-hydroxymethyl) cyclopentyljuridine and determination of its conformation by x-ray crystallography and AM1 theoretical calculations". Nucleosides and Nucleotides 15 6 (1996): 1179-1187. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029932873&partnerID=MN8TOARS.
  309. Gia, O.; Anselmo, A.; Conconi, M.T.; Antonello, C.; Uriarte, E.; Caffieri, S.. "4'-Methyl derivatives of 5-MOP and 5-MOA: Synthesis, photoreactivity, and photobiological activity". Journal of Medicinal Chemistry 39 22 (1996): 4489-4496. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029911840&partnerID=MN8TOARS.
    10.1021/jm960117r
  310. Gatto, B.; Zagotto, G.; Sissi, C.; Cera, C.; Uriarte, E.; Palù, G.; Capranico, G.; Palumbo, M.. "Peptidyl anthraquinones as potential antineoplastic drugs: Synthesis, DNA binding, redox cycling, and biological activity". Journal of Medicinal Chemistry 39 16 (1996): 3114-3122. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029761654&partnerID=MN8TOARS.
    10.1021/jm950924a
  311. Albers, T.; Biagini, S.C.G.; Hibbs, D.E.; Hursthouse, M.B.; Malik, K.M.A.; North, M.; Uriarte, E.; Zagotto, G.. "Desymmetrisation of meso-anhydrides utilising (S)-proline derivatives". Synthesis 3 (1996): 393-398. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029925723&partnerID=MN8TOARS.
  312. Fall, Y.; Santana, L.; Teijeira, M.; Uriarte, E.. "A convenient synthesis of benzofuran-3-acetic acids". Heterocycles 41 4 (1995): 647-650. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001464941&partnerID=MN8TOARS.
  313. Santana, L.; Teijeira, M.; Uriarte, E.; Balzarini, J.; De Clercq, E.. "Synthesis and antiviral activity of 1,2-carbonucleosides". Nucleosides and Nucleotides 14 3-5 (1995): 521-523. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029055952&partnerID=MN8TOARS.
  314. Antonello, C.; Zagotto, G.; Mobilio, S.; Marzano, C.; Gia, O.; Uriarte, E.; Antonello C; et al. "Synthesis and characterization of new methylpsoralens as potential photochemotherapeutic agents". Farmaco 49 4 (1994): 277-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028236746&partnerID=MN8TOARS.
  315. Miranda, R.; Santana, L.; Uriarte, E.; Zagotto, G.. "NMR study of some coumarins and furocoumarins methylated". Spectrochimica Acta Part A: Molecular Spectroscopy 50 1 (1994): 161-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942646782&partnerID=MN8TOARS.
  316. Antonello, C.; Uriarte, E.; Palumbo, M.; Valisena, S.; Parolin, C.; Palù, G.. "Synthesis and biological activity of new quinolone derivatives". European Journal of Medicinal Chemistry 28 4 (1993): 291-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027299053&partnerID=MN8TOARS.
  317. Zagotto, G.; Gia, O.; Baccichetti, F.; Uriarte, E.; Palumbo, M.; Zagotto G; Gia O; et al. "Synthesis and photobiological properties of 4-hydroxymethyl-4'-methylpsoralen derivatives.". Photochemistry and Photobiology 58 4 (1993): 486-491. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027675358&partnerID=MN8TOARS.
    10.1111/j.1751-1097.1993.tb04919.x
  318. Gia, O.; Uriarte, E.; Zagotto, G.; Baccichetti, F.; Antonello, C.; Marciani-Magno, S.. "Synthesis and photobiological activity of new methylpsoralen derivatives". Journal of Photochemistry and Photobiology B: Biology 14 1-2 (1992): 95-104. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026625145&partnerID=MN8TOARS.
    10.1016/1011-1344(92)85085-9
  319. Zagotto, G.; Uriarte, E.; Antonello, C.; Conconi, M.T.; Marciani Magno, S.; Palumbo, M.. "New hydroxy-amido-anthraquinones as potential antineoplastic drugs.". Bioorganic and Medicinal Chemistry Letters 2 7 (1992): 659-662. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026730268&partnerID=MN8TOARS.
  320. Fernández, B.; Mosquera, R.; Uriarte, E.. "Structure-activity relationships in verapamil and analogues using molecular mechanics calculations". International Journal of Pharmaceutics 79 1-3 (1992): 199-203. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026542266&partnerID=MN8TOARS.
  321. D'Auria, M.V.; Minale, L.; Riccio, R.; Uriarte, E.. "Dehydroophioxanthin, a new acetylenic carotenoid sulfate from the ophiuroid Ophiocomina nigra". Journal of Natural Products 54 2 (1991): 606-608. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026009683&partnerID=MN8TOARS.
  322. D'Auria, M.V.; Iorizzi, M.; Minale, L.; Riccio, R.; Uriarte, E.. "Starfish saponins, part 41. Structure of two new steroidal glycoside sulfates (Miniatosides A and B) and two new polyhydroxysteroids from the starfish Patiria miniata". Journal of Natural Products 53 1 (1990): 94-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025267474&partnerID=MN8TOARS.
  323. Eirín, A.; Fernández, F.; Gómez, G.; López, C.; Uriarte, E.. "1H NMR Study of phenanthrylacetic and 2-(phenanthryl)propionic acids". Spectrochimica Acta Part A: Molecular Spectroscopy 46 5 (1990): 843-844. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242625024&partnerID=MN8TOARS.
  324. Antonello C; Uriarte E; Palumbo M; Antonello, C.; Uriarte, E.; Palumbo, M.. "Diethylaminopropionamido-hydroxy-anthraquinones as potential anticancer agents: synthesis and characterization.". Archiv der Pharmazie 322 9 (1989): 541-544. http://europepmc.org/abstract/med/2610587.
    10.1002/ardp.19893220906
  325. Mosquera, R.A.; Uriarte, E.. "A study of the molecular structure of cocaine using molecular mechanics and NMR". Journal of Molecular Structure 195 C (1989): 325-333. http://www.scopus.com/inward/record.url?eid=2-s2.0-0009577481&partnerID=MN8TOARS.
  326. D'Auria, M.V.; Riccio, R.; Uriarte, E.; Minale, L.; Tanaka, J.; Higa, T.. "Isolation and structure elucidation of seven new polyhydroxylated sulfated sterols from the ophiuroid Ophiolepis superba". Journal of Organic Chemistry 54 1 (1989): 234-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001640193&partnerID=MN8TOARS.
  327. Pouilhes, A.; Uriarte, E.; Kouklovsky, C.; Langlois, N.; Langlois, Y.; Chiaroni, A.; Riche, C.. "Chiral a,ß-unsaturated oxazolines in the asymmetric diels-alder reaction". Tetrahedron Letters 30 11 (1989): 1395-1398. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001064472&partnerID=MN8TOARS.
  328. Santana, L.; Cortizo, L.; Uriarte, E.; Garcia-Dominguez, N.; Ravina, E.; Garrido, M.J.. "Preparation of ß-aminomethyl-ß-benzoylpropionic acids and related cis ß-aminomethyl-¿-phenyl-¿-butyrolactones as potential antibacterial agents". Journal de Pharmacie de Belgique 44 2 (1989): 121-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024406165&partnerID=MN8TOARS.
  329. Santana L; Cortizo L; Uriarte E; Garcia-Dominquez N; Raviña E; Garrido MJ. "Preparation of beta-aminomethyl-beta-benzoylpropionic acids and related cis beta-aminomethyl-gamma-phenyl-gamma-butyrolactones as potential antibacterial agents.". (1989): http://europepmc.org/abstract/med/2778622.
  330. Antonello C; Uriarte E; Palumbo M; Antonello, C.; Uriarte, E.; Palumbo, M.. "New anthracenediones with potential anticancer activity: synthesis and characterization of bis-diethylaminopropionamido derivatives.". Archiv der Pharmazie 321 9 (1988): 513-515. http://europepmc.org/abstract/med/3240064.
    10.1002/ardp.19883210904
  331. D'Auria, M.V.; Minale, L.; Riccio, R.; Uriarte, E.. "Marine eicosanoids: Occurrence of 8-(R)-HETE in the starfish Patiria miniata". Experientia 44 8 (1988): 719-720. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344314130&partnerID=MN8TOARS.
    10.1007/BF01941042
  332. Caamaño, O.; Eirín, A.; Fernández, F.; Gómez, G.; Uriarte, E.. "An approach to the enantioselective synthesis of 2-azabicyclo[2.2.1] hept-5-en-3-one(1)". Heterocycles 27 12 (1988): 2839-2841. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750452601&partnerID=MN8TOARS.
  333. Sánchez González A; Uriarte E. "[The NMR technic in pharmaceutical analysis. Quantitative evaluation of cocaine hydrochloride].". (1987): http://europepmc.org/abstract/med/3428415.
  334. Sanchez Gonzalez, A.; Uriarte, E.. "The NMR technique in pharmaceutical analysis. Quantitative evaluation of cocaine hydrochloride | LA TECNICA DE R.M.N. EN EL ANALISIS FARMACEUTICO. VALORACION CUANTITATIVA DEL CLORHIDRATO DE COCAINA". Farmaco, Edizione Pratica 42 10 (1987): 281-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-0343096145&partnerID=MN8TOARS.
  335. Caamano, O.; Eirin, A.; Fernandez, F.; Uriarte, E.. "Semi-rigid models of butyrophenones: Trans-phenyl-[2-(1-piperidinylmethyl)cyclopentyl]methanone". Archiv der Pharmazie 320 5 (1987): 425-429. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023177218&partnerID=MN8TOARS.
  336. Caamano, O.; Fernandez, F.; Eirin, A.; Uriarte, E.; Calleja, J.M.; Gato, A.; Orallo, F.. "Synthesis and neuroleptic activity of some trans-(2-aminomethyl)-cyclopentyl aryl ketones". European Journal of Medicinal Chemistry 22 4 (1987): 311-317. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023226304&partnerID=MN8TOARS.
Capítulo de livro
  1. Sobarzo-Sánchez, E.; Nabavi, S.M.; Rastrelli, L.; Uriarte, E.. "Nanomedicine and Parkinson’s disease: A nanoparticle medical approach". 153-168. 2018.
  2. Yordi, E.G.; Martínez, A.P.; Pérez, R.D.A.; Molina, E.; Santana, L.; Uriarte, E.; Abreu, O.A.; Mat, M.J.. "Ellagic acid: Its importance in diet". 73-110. 2016.
Livro
  1. Concu, R.; Podda, G.; Uriarte, E.; Prado-Prado, F.J.; Del Río Vazquez, M.A.; González-Díaz, H.. A new computational chemistry and complex networks approach to structure-function and similarity relationships in protein enzymes. 2010.
  2. González-Díaz, H.; Ferino, G.; Prado-Prado, F.J.; Vilar, S.; Uriarte, E.; Pazos, A.; Munteanu, C.R.. Protein graphs in cancer prediction. 2010.
    10.1007/978-90-481-2675-0_7

Outros

Outra produção
  1. Study of 3-(4’-Nitrobenzamido)coumarin using an Alzheimer’s Disease Model. 2021. Rodríguez-Enríquez F; Viña D; Uriarte E; Fontenla JÁ; Matos MJ. http://europepmc.org/abstract/PPR/PPR287395.
    10.21203/rs.3.rs-226609/v1