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Identificação

Identificação pessoal

Nome completo
Maria João Correia Pinto Carvalho de Matos

Identificadores de autor

Ciência ID
6F1F-ECC4-2714
ORCID iD
0000-0002-3470-8299

Endereços de correio eletrónico

  • mariajoao.correiapinto@usc.es (Profissional)
  • mariacmatos@gmail.com (Pessoal)

Websites

Domínios de atuação

  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Italiano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Galego Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Projetos

Projeto

Designação Financiadores
2023 - 2026 Towards a personalized medicine for Amyotrophic Lateral Sclerosis: ROS-sensitive nanoparticles as carriers for combined drug delivery
2023.13291.PEX
Investigador
Universidade do Porto, Portugal
 FCT, Fundação para a Ciência e Tcnologia
Em curso
Produções

Publicações

Artigo em revista
  1. Giovanna Delogu; Michela Begala; Maria Matos; Davide Crucitti; Valeria Sogos; Benedetta Era; Antonella Fais. "A New Class of Benzo[b]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies". Molecules (2024): https://doi.org/10.3390/molecules29163748.
    10.3390/molecules29163748
  2. Estela Guardado Yordi; Amaury Pérez Martínez; Matteo Radice; Laura Scalvenzi; Reinier Abreu-Naranjo; Eugenio Uriarte; Lourdes Santana; Maria Joao Matos. "Seaweeds as Source of Bioactive Pigments with Neuroprotective and/or Anti-Neurodegenerative Activities: Astaxanthin and Fucoxanthin". Marine Drugs (2024): https://doi.org/10.3390/md22070327.
    10.3390/md22070327
  3. Maria-Jesus Blanco; Joanne Bronson; Erin F. DiMauro; Carolyn Dzierba; MariJean Eggen; Amanda Garner; Gunda Georg; et al. "Empowering Voices: Inspiring Women in Medicinal Chemistry". Journal of Medicinal Chemistry (2024): http://dx.doi.org/10.1021/acs.jmedchem.4c00493.
    10.1021/acs.jmedchem.4c00493
  4. Maria-Jesus Blanco; Joanne Bronson; Erin F. DiMauro; Carolyn Dzierba; MariJean Eggen; Amanda Garner; Gunda Georg; et al. "Empowering Voices: Inspiring Women in Medicinal Chemistry". ACS Medicinal Chemistry Letters (2024): http://dx.doi.org/10.1021/acsmedchemlett.4c00097.
    10.1021/acsmedchemlett.4c00097
  5. André Rogerio Pereira; Ashley Silva Campos; Maria João Matos; Edson Luis Maistro. "Study of the DNA damage and cell death in human peripheral blood mononuclear and HepG2/C3A cells exposed to the synthetic 3-(3-hydroxyphenyl)-7-hydroxycoumarin". Journal of Toxicology and Environmental Health, Part A (2024): http://dx.doi.org/10.1080/15287394.2023.2274331.
    10.1080/15287394.2023.2274331
  6. David Cabezas; Guido Mellado; Nicolás Espinoza; José Antonio Gárate; César Morales; Alejandro Castro-Alvarez; Maria J. Matos; Marco Mellado; Jaime Mella. "In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies". Journal of Biomolecular Structure and Dynamics (2023): https://doi.org/10.1080/07391102.2023.2172457.
    10.1080/07391102.2023.2172457
  7. Paulo Gaio Leite; Allysson Thiago Cramer Soares; Natália Fernanda de Melo Oliveira; Samuel Porto; Lucas Kramer; Rayane Aparecida Nonato Rabelo; Rafaela das Dores Pereira; et al. "N-(coumarin-3-yl)cinnamamide Promotes Immunomodulatory, Neuroprotective, and Lung Function-Preserving Effects during Severe Malaria". Pharmaceuticals (2023): https://www.mdpi.com/1424-8247/17/1/46.
    10.3390/ph17010046
  8. Antonella Fais; Francesca Pintus; Benedetta Era; Sonia Floris; Amit Kumar; Debapriyo Sarmadhikari; Valeria Sogos; et al. "Front Cover: Design of 3-Phenylcoumarins and 3-Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies (ChemMedChem 21/2023)". ChemMedChem (2023): https://doi.org/10.1002/cmdc.202300595.
    10.1002/cmdc.202300595
  9. Antonella Fais; Francesca Pintus; Benedetta Era; Sonia Floris; Amit Kumar; Debapriyo Sarmadhikari; Valeria Sogos; et al. "Design of 3-Phenylcoumarins and 3-Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies". ChemMedChem (2023): https://doi.org/10.1002/cmdc.202300400.
    10.1002/cmdc.202300400
  10. Aitor Carneiro; Lourdes Santana; Maria João Matos. "Oxidation-labile linkers for controlled drug delivery". Bioorganic & Medicinal Chemistry Letters (2023): https://doi.org/10.1016/j.bmcl.2023.129264.
    10.1016/j.bmcl.2023.129264
  11. Maria J. Matos; Paula Novo; Lucía Mayán; Iria Torres; Eugenio Uriarte; Matilde Yáñez; José Ángel Fontenla; et al. "8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies". European Journal of Medicinal Chemistry (2023): https://doi.org/10.1016/j.ejmech.2023.115091.
    10.1016/j.ejmech.2023.115091
  12. Aitor Carneiro; Eugenio Uriarte; Fernanda Borges; Maria João Matos. "Propargylamine: an important moiety in drug discovery". Future Medicinal Chemistry (2023): https://doi.org/10.4155/fmc-2022-0243.
    10.4155/fmc-2022-0243
  13. Laura Fernández-Peña; Maria João Matos; Enol López. "Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation". Marine Drugs (2022): https://doi.org/10.3390/md21010037.
    10.3390/md21010037
  14. Maria João Matos; Eugenio Uriarte; Nuria Seoane; Aitor Picos; José Gil-Longo; Manuel Campos-Toimil. "Front Cover: Synthesis and Vasorelaxant Activity of Nitrate-Coumarin Derivatives (ChemMedChem 21/2022)". ChemMedChem (2022): https://doi.org/10.1002/cmdc.202200567.
    10.1002/cmdc.202200567
  15. Maria João Matos; Eugenio Uriarte; Nuria Seoane; Aitor Picos; José Gil-Longo; Manuel Campos-Toimil. "Synthesis and Vasorelaxant Activity of Nitrate-Coumarin Derivatives". ChemMedChem (2022): https://doi.org/10.1002/cmdc.202200476.
    10.1002/cmdc.202200476
  16. Francesca Pintus; Sonia Floris; Antonella Fais; Benedetta Era; Amit Kumar; Gianluca Gatto; Eugenio Uriarte; Maria João Matos. "Hydroxy-3-Phenylcoumarins as Multitarget Compounds for Skin Aging Diseases: Synthesis, Molecular Docking and Tyrosinase, Elastase, Collagenase and Hyaluronidase Inhibition, and Sun Protection Factor". Molecules (2022): https://doi.org/10.3390/molecules27206914.
    10.3390/molecules27206914
  17. Castanha APM; Almeida-Terassi LM; Guardado-Yordi E; Matos MJ; Maistro EL. "Cytogenotoxicity assessment of 3-(3,4-dihydroxyphenyl)-7,8-dihydroxycoumarin on HepG2/C3A cells and leukocytes.". Journal of applied toxicology : JAT (2022): http://europepmc.org/abstract/med/36000810.
    10.1002/jat.4384
  18. Maria J. Matos; Lourdes Santana; Eugenio Uriarte; Fernanda Borges. "Thiocoumarins: From the Synthesis to the Biological Applications". Molecules (2022): https://doi.org/10.3390/molecules27154901.
    10.3390/molecules27154901
  19. Maria João Matos; Maria-Jesus Blanco. "Medicinal Chemistry in Portugal and Spain: A Strong Iberian Alliance". ACS Medicinal Chemistry Letters (2022): https://doi.org/10.1021/acsmedchemlett.2c00194.
    10.1021/acsmedchemlett.2c00194
  20. Maria João Matos. "Treating neurodegenerative diseases with multitarget drugs: an interview with Maria João Matos". Future Medicinal Chemistry (2022): https://doi.org/10.4155/fmc-2022-0077.
    10.4155/fmc-2022-0077
  21. Xhenti Ferhati; Ester Jiménez-Moreno; Emily A. Hoyt; Giulia Salluce; Mar Cabeza-Cabrerizo; Claudio D. Navo; Ismael Compañón; et al. "Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry". Journal of the American Chemical Society 144 12 (2022): 5284-5294. https://doi.org/10.1021/jacs.1c07675.
    10.1021/jacs.1c07675
  22. Giovanna L. Delogu; Antonella Fais; Francesca Pintus; Chinmayi Goyal; Maria J. Matos; Benedetta Era; Amit Kumar. "Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold". Pharmaceuticals (2022): https://doi.org/10.3390/ph15030304.
    10.3390/ph15030304
  23. "A comprehensive ethnobotanical profile of Ocimum campechianum (Lamiaceae): from traditional medicine to phytochemical and pharmacological evidences". Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology (2022): 1-17. http://dx.doi.org/10.1080/11263504.2022.2056647.
    10.1080/11263504.2022.2056647
  24. Maria J. Matos; Dolores Viña; Lourdes Santana; Eugenio Uriarte. "Facing Novel Challenges in Neurodegenerative Diseases Drug Discovery: From Small Molecules to Targeted Therapies". Proceedings (2019): https://www.mdpi.com/2504-3900/22/1/14.
    10.3390/proceedings2019022014

Outros

Outra produção
  1. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry.. 2022. Xhenti Ferhati; Ester Jiménez-Moreno; Emily Hoyt; Giulia Salluce; Mar Cabeza-Cabrerizo; Claudio D. Navo; Ismael Compañón; et al.
    10.17863/cam.82214
  2. Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates.. 2018. Maria J. Matos; Carlos Labão-Almeida; Claire Sayers; Oyinlola Dada; Matthias Tacke; Gonçalo J. L. Bernardes.
    10.17863/CAM.26706
  3. A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging.. 2018. Benjamin Stenton; Bruno Oliveira; Maria J. Matos; Laura Sinatra; Gonçalo J. L. Bernardes.
    10.17863/CAM.25027