Identification
Personal identification
- Full name
- Pedro Manuel Henriques Marques Matias
Citation names
- Matias, Pedro M
Author identifiers
- Ciência ID
- 781D-CE99-A983
- ORCID iD
- 0000-0001-6170-451X
- Scopus Author Id
- 6603792037
Addresses
- Instituto de Tecnologia Química e Biológica. Apartado 127, 2781-901, OEIRAS, Oeiras, Portugal (Professional)
Websites
- http://www.itqb.unl.pt/research/biological-chemistry/industry-and-medicine-applied-crystallography (Professional)
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) | Advanced (C1) |
French | Intermediate (B1) | Intermediate (B1) | Beginner (A1) | Intermediate (B1) | Intermediate (B1) |
Spanish; Castilian | Beginner (A1) | Intermediate (B1) | Beginner (A1) | Beginner (A1) | Intermediate (B1) |
Education
Degree | Classification | |
---|---|---|
1983/09 - 1986/11
Concluded
|
Ph.D. in Crystallography (Doctor of Philosophy)
University of Pittsburgh, PA 15260, EUA, United States
""X-ray and Neutron Diffraction Studies of Small Organic Molecules: Deuterionitromethane, Ethylene Carbonate, Isopropyl 1-S-beta-D-Galactopyrano-side
monohydrate and Diacetamide (cis-trans )"" (THESIS/DISSERTATION)
|
Approved |
1977/10 - 1983/06
Concluded
|
Chemical Engineering - Chemistry and Processes (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"n/a" (THESIS/DISSERTATION)
|
17 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2015 - Current | Principal Investigator (Research) | Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal |
2008/03/11 - Current | Principal Investigator (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
1995/11/02 - 2008/03/10 | Auxiliary Researcher (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
1992/11/02 - 1995/11/01 | Research Assistant (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2014 - Current | Associate Professor (University Teacher) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
1990/01/01 - 1992/11/01 | Assistant Professor (University Teacher) | Universidade de Lisboa Instituto Superior Técnico, Portugal |
Positions / Appointments
Category Host institution |
Employer | |
---|---|---|
2024/03 - Current | Coordinator of the Macromolecular Crystallography Unit | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2022 - Current | Member of the Institute Council of ITQB NOVA | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2015 - Current | Member of the Directive Board | Universidade Nova de Lisboa Microbiologia Molecular Estrutural e Celular, Portugal |
2016 - 2022 | Member of the Scientific Council of ITQB NOVA | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2016 - 2022 | Coordinator of the Biological Chemistry Division | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2008/01/01 - 2023/04/30 | Head of the Unit Structural Biology for Drug Development | Instituto de Biologia Experimental e Tecnológica, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2019/09/01 - 2023/02/28 | IMpaCT - Imaging life from Molecules to cells - building knowledge on Cryo-electron microscopy methodologies at ITQB NOVA
Principal investigator
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
European Research Executive Agency
Concluded
|
2016/01 - 2018/12 | Engineering a highly active NiFeSe Hydrogenase for electrocatalytic and photocatalytic applications
Principal investigator
|
Fundação para a Ciência e a Tecnologia, I.P. |
2016/01 - 2018/12 | Structure and Function of a Dodecameric Molecular Machine: the human RuvBL1/RuvBL2 Complex and its Role in Disease
Researcher
|
Fundação para a Ciência e a Tecnologia |
2013/06 - 2015/05 | Structural and functional insights into centriole biogenesis
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2013/03 - 2015/03 | Structural Determinants of Oxygen Tolerance in a NiFeSe Hydrogenase
Principal investigator
|
Fundação para a Ciência e a Tecnologia, I.P. |
2011/03 - 2014/08 | Structural determinants of superoxide reduction - A detoxification system essential for life
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2010/01 - 2013/06 | Engineering mini Superoxide Dismutases with tunable redox properties
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2010/02 - 2013/02 | Mind the gap: How extracellular respiration is linked across the periplasmic space to the cytoplasmic oxidation of substrates.
A key step in bioenergy harvesting.
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2008/01 - 2011/09 | Towards biohydrogen production - study of a high-activity, oxygen-resistant bacterial hydrogenase
Principal investigator
|
Fundação para a Ciência e a Tecnologia, I.P. |
2008/01 - 2011/06 | Molecular Adaptation to Extreme Environments: Structural Studies of Proteins Involved in the Synthesis of Osmolytes in (hyper)thermophylic
micro-organisms
Principal investigator
|
Fundação para a Ciência e a Tecnologia, I.P. |
2008/01 - 2011/03 | Iron Metabolism Study in Deinococcus radiodurans- Novel strategies
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2008/02 - 2011/01 | Iron metabolism in sulphate reducing bacteria
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
2008/01 - 2009/12 | A structural genomics approach to membrane transport proteins from Archaea
Researcher
|
Fundação para a Ciência e a Tecnologia, I.P. |
Outputs
Publications
Book |
|
Book chapter |
|
Encyclopedia entry |
|
Journal article |
|
Preprint |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2022/03/20 | A structural overview of RuvBL1, RuvBL2 and their complexes | IMpaCT Tomography Workshop
Weizmann Institute of Science (Rehovot, Israel)
|
2021/12/14 | Catching up with the CryoEM Resolution Revolution |
ITQB NOVA (virtual) (Oeiras, Portugal)
|
2019/06/14 | Improving the O2 tolerance of a [NiFeSe] hydrogenase | 1st National Crystallographic Meeting
Universidade de Aveiro (Aveiro, Portugal)
|
2019/04/01 | Improving the O2 tolerance of a [NiFeSe] hydrogenase | 12th International Conference on Hydrogenases and other Redox (Bio)catalysts for Energy Conversion
(Lisboa, Portugal)
|
2018/07/03 | The Portuguese Beam Allocation Group at the ESRF: a 19-year old success history (1999-2018) | Encontro Ciência 2018
(Lisboa, Portugal)
|
2014/11/04 | A structural Overview of Pontin (RuvBL1), Reptin (RuvBL2) and their complex(es) | PSDI 2014 – 22nd Protein Structure Determination in Industry Conference
Merck KgaA (Cascais)
|
2013/07/09 | Redox State-Dependent Structural Changes in [NiFeSe] Hydrogenase from Desulfovibrio vulgaris Hildenborough | 10th International Hydrogenase Conference
(Szeged, Hungary)
|
2013/02/14 | The Portuguese MX Block Allocation Group at the ESRF: a 14-year success history (1999-2013) | 2º Encontro Nacional de Utilizadores de Radiação Sincrotrão
(Lisboa)
|
2012/10/17 | A structural Overview of Pontin (RuvBL1), Reptin (RuvBL2) and their complex(es) | First International Meeting on Reptin and Pontin
(Bordéus, France)
|
2011/05/06 | The Three Dimensional Structure of a Dodecameric Molecular Machine – The RuvBL1/RuvBL2 Complex | INTERBIO Symposium Frontiers in Protein Research
(Oeiras, Portugal)
|
2010/09/14 | Structural Analysis of Thermus thermophilus HB27 Mannosyl-3-Phosphoglycerate Synthase | 8th International Congress on Extremophiles
(Ponta Delgada, Portugal)
|
2006/07/24 | Three-dimensional structure of a ferritin from the hyperthermophilic archaeon and anaerobe Pyrococcus furiosus | 2006 Annual Meeting of the American Crystallographic Association
American Crystallographic Association (Honolulu)
|
2005/08/25 | The activation process of D.desulfuricans ATCC 27774 [NiFe] Hydrogenase | IUCr 2005 - XX Congress of the International Union of Crystallography
International Union of Crystallography (Florença, Italy)
|
2003/08/26 | Sulfate respiration in Desulfovibrio bacteria: a Short Crystallographic Overview | ECM-21 - 21st congress of the European Crystallographic Association
European Crystallographic Association (Durban, South Africa)
|
2001/07/01 | Hydrogen recycling in D.desulfuricans ATCC 27774: crystallographic and molecular modelling studies on the periplasmic electron transfer chain | Joint 27th FEBS Meeting and PABMB Meeting
FEBS (Lisboa, Portugal)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2020/01/02 - 2023/12/31 | Structure and Function of a Dodecameric Molecular Machine: the Human RuvBL1/RuvBL2 Complex and its Role in Disease
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2019/10/01 - 2023/09/30 | Biocatalytic H2 production with a high activity [NiFeSe] hydrogenase
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2020/09/01 - 2022/03/16 | X-ray crystal structure of Human GAPDH with a selective inhibitor
Co-supervisor
|
Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2015/09/01 - 2020/12/31 | Structural and Functional insights into a dodecameric machine
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2015/09/01 - 2019/11/07 | Engineering a [NiFeSe] Hydrogenase for an efficient hydrogen production
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2017/09/01 - 2019/02/15 | Cyclophilin D as a multiple sclerosis and cardiovascular disease drug target
Co-supervisor
|
Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2017/09/01 - 2018/10/31 | CRYSTAL STRUCTURE OF BONE MARROW TYROSINE KINASE FROM CHROMOSOME X WITH COVALENT LIGANDS
Co-supervisor
|
Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2013/01/01 - 2017/11/27 | Structural insights into the human multifunctional protein RuvBL2
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2010/09/01 - 2014/12/17 | Structural and functional studies of a high-activity [NiFeSe] hydrogenase
Co-supervisor
|
Biociências Moleculares (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2005/09/01 - 2012/05/11 | Structural studies on the structure-function relationship in a glycosyltransferase, a phosphatase and an oxidorreductase.
Supervisor
|
Bioquímica (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2022/07/10 - 2022/07/15 | 7th European Crystallographic School - ECS7 (2022/07/10 - 2022/07/15)
Workshop (Member of the Organising Committee)
|
Universidade de Lisboa Instituto Superior Técnico, Portugal |
2019/03/31 - 2019/04/04 | 12th International Conference on Hydrogenases and other Redox (Bio)catalysts for Energy Conversion (2019/03/31 - 2019/04/04)
Congress (Member of the Organising Committee)
|
Universidade Nova de Lisboa, Portugal |
2016/06/17 - 2016/06/17 | 5º Encontro Nacional de Utilizadores de Radiação Sincrotrão (2016/06/17)
Meeting (Member of the Organising Committee)
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2016/01/31 - 2016/02/02 | BioStruct-X Workshop on Ensemble Refinement of Protein Crystal Structures (2016/01/31)
Workshop (Member of the Organising Committee)
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2014/10/10 - 2014/10/12 | Second International Workshop on Reptin and Pontin, 10 a 12 de Outubro de 2014, Oeiras, Portugal. (2014/10/10)
Workshop (Member of the Organising Committee)
|
Instituto de Biologia Experimental e Tecnológica, Portugal |
2006/07/02 - 2006/07/07 | Eurobic 8, the 8th European Biological Chemistry Conference, 2 a 7 de Julho de 2006, Aveiro, Portugal (2006/07/02)
Congress (Member of the Organising Committee)
|
Universidade de Aveiro, Portugal |