Diana Lina Jerónimo da Cunha Reis (1F1E-73C0-FD44)

Curriculum Vitae

Diana Cunha-Reis (DCR) is currently a Junior Researcher at Biosystems and Integrative Sciences Institute and Departamento de Química e Bioquímica (DQB), Faculty of Sciences, University of Lisbon (FCUL), Portugal. She is also course responsible and lecturer of the Physiology course, Biochemistry BSc degree, DQB, FCUL and secretary of the Portuguese Physiological Society. She graduated in Biochemistry in 1999 at the FCUL and completed her PhD in Biomedical Sciences, Neuroscience Specialty at the Faculty of Medicine, University of Lisbon (FMUL), Portugal in 2007. As part of her PhD studies she was a visiting fellow at the Rudolph-Boehm Institute for Pharmacology and Toxicology, Faculty of Medicine, University of Leipzig, Germany and Swammerdam Institute for Neurobiology, Faculty of Biology, University of Amsterdam, The Netherlands. From 2007 to 2010 DCR was a postdoctoral research fellow at the Neuroscience unit, Instituto de Medicina Molecular, FMUL, Portugal. From January 2012 to December 2017 DCR was a postdoctoral researcher fellow at Centro de Química e Bioquímica, DQB, FCUL, Instituto de Medicina Molecular and and Clínica Universitária de Neurologia, FMUL, Portugal. From September 2012 to September 2014, DCR was assistant professor in Human Physiology (course responsible) at ECTS, Universidade Lusófona de Humanidades e Tecnologias, Lisbon, Portugal. DCR was evaluator and reporter of the 2019 call of the of the Marie Sklodowska Curie Individual Fellowships H2020 MSCA IF 2019 European Global Fellowships and of the 2013 and 2014 calls (FP7 and H2020 European commission programs, respectively) of the Marie Curie Initial Training Networks (ITN).She supervised 8MSc students and one PhD student she currently supervises one MSc student in Human Biology and Environment. She currently studies: 1) The value of VPAC1 VIP receptor antagonists in reversing the plastic changes following in vitro seizures and its contributions to the epileptogenesis process in TLE; 2) Cognitive rescue in TLE and aging using novelty training strategies and VIP receptor ligands; 3) the changes in membrane lipid composition and lipid raft dynamics in TLE and the ability of the ketogenic diet therapy to reverse them.

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Identificação

Identificação pessoal

Nome completo: Diana Lina Jerónimo da Cunha Reis

Nomes de citação

Cunha-Reis, Diana

Identificadores de autor

Ciência ID: 1F1E-73C0-FD44
ORCID iD: 0000-0002-0900-9306
Google Scholar ID: e6U9J70AAAAJ
Researcher Id: F-1689-2011
Scopus Author Id: 8571270200

Domínios de atuação

Ciências Médicas e da Saúde - Medicina Básica - Neurociências
Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
Ciências Naturais - Ciências Biológicas - Bioquímica
Ciências Naturais - Ciências Biológicas - Biologia das Ciências do Comportamento

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Inglês	Utilizador independente (B1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador independente (B1)
Francês	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador independente (B1)
Espanhol; Castelhano	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2007/06/26 Concluído	Doutoramento em Ciências Biomédicas (Doutoramento) Especialização em Neurociências Básicas Universidade de Lisboa Faculdade de Medicina, Portugal "VIP increases GABAergic transmission to interneurones and pyramidal cells in the hippocamapus: consequences for pyramidal cell activity and modulation by endogenous adenosine." (TESE/DISSERTAÇÃO)	Aprovado com distinção e louvor
1999/01 Concluído	Bioquímica (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal "Modulação pelo péptido vasoactivo intestinal da transmissão sináptica no hipocampo de rato." (TESE/DISSERTAÇÃO)

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2019/07/01 - Atual	Investigador Contratado (Investigação)	Universidade de Lisboa Faculdade de Ciências, Portugal
	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2013 - 2014	Professor Auxiliar (Docente Universitário)	Universidade Lusófona de Humanidades e Tecnologias, Portugal

Cargos e Funções

	Categoria Profissional Instituição de acolhimento	Empregador
2019/10/01 - 2022/11/11	Secretary	Sociedade Portuguesa de Fisiologia, Portugal
	Sociedade Portuguesa de Fisiologia, Portugal
2019/09/01 - 2021/07/31	Physiology course responsible, Biochemistry BSc	Universidade de Lisboa Faculdade de Ciências, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2022/11/16 - Atual	Review editor Frontiers in Cellular Neuroscience	Frontiers Media SA, Suiça
	Frontiers Media SA, Suiça
2022/10/06 - 2022/11/24	Evaluator and reporter of the proposals submitted to the 2022 call of the of the Marie Sklodowska Curie Actions Postdoctoral Fellowships H2021 MSCA PF 2021	European Commission, Bélgica
	EU Framework Programme for Research and Innovation Excellent Science, Bélgica
2018/07/01 - 2022/06/30	PI of the project 'Contribution of neuronal membrane and lipid raft remodeling to the pathophysiology of mesial temporal lobe epilepsy (MTLE): insight into the beneficial effects of the ketogenic diet	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal
2021/11 - 2021/12	Evaluator of proposals submitted to the 2021 call of the of the Marie Sklodowska Curie Actions Postdoctoral Fellowships H2021 MSCA PF 2021	EU Framework Programme for Research and Innovation Excellent Science, Bélgica

2020/10/02 - 2020/12/04	Evaluator of proposals submitted to the 2020 call of the of the Marie Sklodowska Curie Individual Fellowships H2020 MSCA IF 2020 European Global Fellowships	EU Framework Programme for Research and Innovation Excellent Science, Bélgica
	Research Executive Agency, Bélgica
2019/09 - 2019/11	Evaluator of proposals submitted to the 2019 call of the of the Marie Sklodowska Curie Individual Fellowships H2020 MSCA IF 2019 European Global Fellowships	EU Framework Programme for Research and Innovation Science with and for Society, Bélgica

2012/01/01 - 2019/06/30	Postdoctoral research fellow - Evaluating therapeutic opportunities for preventing epileptogenesis, cognitive decline and sudden death in epilepsy (SFRH/BPD/81358/2011).	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal
2013/07/01 - 2017/12/31	PI of the project 'Evaluating therapeutic opportunities for preventing sudden death in epilepsy', AIDFM EPI-428, FML, internal funding, 10K€)	Universidade de Lisboa Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal
	Universidade de Lisboa Faculdade de Medicina, Portugal
2013/02 - 2016/07	Invited lecturer Physiology Health Sciences degree	Universidade de Lisboa Faculdade de Medicina, Portugal

2012/09/01 - 2014/09/01	Assistant professor in Human Physiology (course director, Pharmacological Sciences MSc). Physiology (course director, Nutrition degree).	Universidade Lusófona de Humanidades e Tecnologias, Portugal

2014/04/01 - 2014/06/01	Evaluator and rapporteur of proposals submitted to the 2014 call of the Marie Curie Initial Training Networks (ITN) program.	Horizon 2020 European Innovation Council Fast Track to Innovation, Bélgica

2010/02/01 - 2013/07/31	PI of project 'Role of VIP receptors in hippocampal dependent cognition and synaptic plasticity: therapeutic potential of VPAC1 receptor antagonists to ameliorate the cognitive deficits in MTLE'	Instituto de Medicina Molecular, Portugal

2012/10/01 - 2013/02/28	Evaluator and rapporteur of proposals submitted to the 2013 call of the Marie Curie Initial Training Networks (ITN) program.	European Commission Seventh Framework Programme for Research and Technological Development, Bélgica

2011/05/01 - 2011/12/31	Researcher (SARIN Educational Fellowship).	Universidade de Lisboa Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

2008/02/01 - 2010/07/31	Invited Lecturer of the Neurochemistry course	Universidade de Lisboa Faculdade de Ciências, Portugal

2007/07/01 - 2010/06/30	Postdoctoral research fellow (FCT, SFRH/BPD/34661/2007) at the Institute of Pharmacology and Neurosciences, IMM, ULisboa	Fundação para a Ciência e a Tecnologia, Portugal
	Instituto de Medicina Molecular, Portugal
2007/10/01 - 2009/02/15	Invited teaching Assistant (electrophysiology experimental work of the Neuroscience Master Course	Universidade de Lisboa Faculdade de Medicina, Portugal

2008/03/01 - 2008/12/15	Member of the Organizing Commitee of the 39th Annual Meeting of Portuguese Pharmacological Society	Sociedade Portuguesa de Farmacologia, Portugal

1998/07/15 - 2007/09/15	Invited teaching assistant of the practical intensive course of the Neuroscience discipline	Universidade de Lisboa Faculdade de Medicina, Portugal

2000/09/01 - 2006/10/31	PhD Student SFRH/BD/889/2000 at the Faculty of Medicine, Univ. Lisbon, Fac. Biology, Univ. Amsterdam and Faculty of Medicine, Univ. Leipzig	Fundação para a Ciência e a Tecnologia, Portugal

2000/09/01 - 2000/12/31	research fellow of the COST B10 Program	Universiteit van Amsterdam Swammerdam Institute for Life Sciences, Países Baixos

1999/02/01 - 2000/08/31	research fellow GGPXXI/BIC/4437/96 and PRAXIS XXI/BIC/17319/99	Universidade de Lisboa Faculdade de Medicina, Portugal

1997/10/01 - 1999/01/31	undergraduate research fellow PRAXIS XXI/BICJ/17319/99 of PRAXIS 2/2.1/BIA/137/94	Universidade de Lisboa Faculdade de Medicina, Portugal

Projetos

Bolsa

	Designação	Financiadores
2023/01/14 - 2023/12/31	Investigating altered lipid raft dynamics following seizures at hippocampal synapses P08.C BioISI 2023 Investigador responsável Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018/07 - 2022/06	Contribuição da reorganização das membranas e jangadas lipídicas para a fisiopatologia da epilesia mesial temporal com esclerose do hipocampo (MTLE-HS): relação com o tratamento com dieta cetogénica. 149547PRJ	Fundação para a Ciência e a Tecnologia
2012/01/01 - 2017/12/31	EVALUATING THERAPEUTIC OPPORTUNITIES FOR PREVENTING EPILEPTOGENESIS, COGNITIVE DECLINE AND SUDDEN DEATH IN EPILEPSY SFRH/BPD/81358/2011 33546DFA	Fundação para a Ciência e a Tecnologia Concluído
2010/02 - 2013/07	Genetic modification of the paraventricular nucleus of the hypothalamus (PVN) and rostroventrolateral medula (RVLM) cells to control hypertension chronically. Provided by PTCRIS: 109081 Investigador Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia
2010/02 - 2013/07	On the role of VIP receptors in hippocampal dependent cognition and synaptic plasticity: evaluation of the therapeutic potential of VPAC1 receptor antagonists to ameliorate the cognitive deficits in TLE Provided by PTCRIS: 103639 103639 Investigador responsável Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010/02 - 2013/07	Papel dos receptores para o VIP na aprendizagem e plasticidade sináptica dependente do hipocampo: avaliação do potencial terapeutico de antagonistas dos receptores VPAC1 para mitigar as deficiências cognitivas em na ELT. 103639PRJ	Fundação para a Ciência e a Tecnologia
2009/10 - 2011/05	Membrane receptors and mediators involved in plastic changes induced by neuronal insults: implications for neuroprotection Provided by PTCRIS: 68607 Bolseiro de Pós-Doutoramento Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007/07/01 - 2010/06/30	ROLE OF VIP CONTAINING INTERNEURONES IN THE CONTROL OF THE RAT HIPPOCAMPAL CIRCUITS DURING LOCOMOTION, EXPLORATION AND IN EPILEPSY SFRH/BPD/34661/2007 22310DFA	Fundação para a Ciência e a Tecnologia Concluído
2007/07 - 2009/06	Neurotrophins and neuronal communication: fine tuning by adenosine Provided by PTCRIS: 56332 Bolseiro de Pós-Doutoramento Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2005/08 - 2007/06	Neurotrophins and neuronal communication: fine tuning by adenosine Provided by PTCRIS: 82305 Bolseiro de Pós-Doutoramento	Fundação para a Ciência e a Tecnologia Concluído
2003 - 2006	Modulation of synaptic transmission in interneurons: role of adenosine POCTI/37398/NSE/2001 Bolseiro de Doutoramento	Fundação para a Ciência e a Tecnologia Concluído

Projeto

	Designação	Financiadores
2019/07/01 - Atual	Alternative therapeutic strategies to the treatment of drug-refractory temporal lobe epilepsy DL 57/2016/CP1479/CT0044 Investigador Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2019/07/01 - 2025/06/30	Not Available DL 57/2016/CP1479/CT0044 10.54499/DL57/2016/CP1479/CT0044 Universidade de Lisboa Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/01 - 2022/06/30	Contribution of neuronal membrane and lipid raft remodelling to the pathophysiology of mesial temporal lobe epilepsy (MTLE): insight into the beneficial effects of the ketogenic diet therapy. PTDC/SAU-PUB/28311/2017 LISBOA-01-0145-FEDER-028311 Investigador responsável FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Universidade do Porto, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Ministério da Ciência Tecnologia e Ensino Superior Concluído
2019/01/01 - 2019/12/31	Biosystems & Integrative Sciences Institute UID/Multi/04046/2019 FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal Universidade do Minho, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2019/01/01 - 2019/12/31	Center of Chemistry and Biochemistry UID/Multi/00612/2019 FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Universidade de Lisboa Centro de Química e Bioquímica, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2019/01/01 - 2019/12/31	Instituto de Medicina Molecular UID/BIM/50005/2019 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2012/01/01 - 2019/06/30	Evaluating therapeutic opportunities for preventing epileptogenesis, cognitive decline and sudden death in epilepsy SFRH/BPD/81358/2011 Bolseiro de Pós-Doutoramento Universidade de Lisboa Centro de Química e Bioquímica, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2013/03/01 - 2016/09/30	New approaches for preventing epileptogenesis, cognitive decline and sudden death in a rat model of temporal lobe epilepsy: training in novelty exploration tasks and the role of VIP VPAC1 receptors SFRH/BD/88350/2012 Orientador Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Desativado
2010/02/01 - 2013/07/31	On the role of VIP receptors in hippocampal dependent cognition and synaptic plasticity: evaluation of the therapeutic potential of VPAC1 receptor antagonists to ameliorate the cognitive deficits in TLE PTDC/SAU-NEU/103639/2008 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/04/01 - 2013/02/28	Development and behavioural characterization of a rat model of MTLE PTDC/SAU-NEU/103639/2008 Orientador Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia
2010/03/01 - 2010/09/30	Involvement of AMPA receptor phosphorylation in VIP modulation of LTP in hippocampal CA1 area PTDC/SAU-NEU/103639/2008 Orientador Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007/07/01 - 2010/06/30	Role of VIP containing interneurones in the control of the rat hippocampal circuits during locomotion, exploration and in epilepsy SFRH/BPD/34661/2007 Bolseiro de Pós-Doutoramento Instituto de Medicina Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2005/08/15 - 2007/06/30	Neurotrophins and neuronal communication: fine tuning by adenosine POCI/SAU-NEU/56332/2004 Bolseiro de Doutoramento Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2000/09/01 - 2004/12/31	Modulation by Vasoactive intestinal peptide (VIP) increases GABAergic transmission to interneurones and pyramidal cells in the hippocampus: consequences for pyramidal cell activity and modulation by endogenous adenosine SFRH/BD/889/2000 Bolseiro de Doutoramento Universidade de Lisboa Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1999/02/01 - 2000/08/31	Modulation of hippocampal synaptic transmission and GABA release by VIP PRAXIS XXI/BIC/17319/99 Bolseiro de Investigação Universidade de Lisboa Faculdade de Medicina, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em conferência	Bento, Marta; Serpa, Andre; Caulino-Rocha, Ana; Seweryn Pawlak; Cunha-Reis, Diana. "VPAC1 and VPAC2 receptors are opposingly altered in the Li2+-pilocarpine model of temporal lobe epilepsy". Trabalho apresentado em 2nd International Meeting of the Portuguese Society of Physiology, Coimbra, 2022. No prelo Cunha-Reis, Diana. "Exploring the role of metaplasticity in synaptic function under physiological conditions and in animal models of aging and epilepsy using integrative approaches". Trabalho apresentado em 2nd International Meeting of the Portuguese Society of Physiology, Coimbra, 2022. No prelo Bento, Marta; Caulino-Rocha, Ana; Cunha-Reis, Diana. "Postweaning development influences synaptic VPAC1 and VPAC2 receptor expression and the expression and phosphorylation of AMPA GluA1 and GluA2 subunits". Trabalho apresentado em 2nd International Meeting of the Portuguese Society of Physiology, Coimbra, 2022. No prelo Laia Amat-Garcia; Nádia Carolina Rodrigues; Carvalho-Rosa, JD; Isabel Silva; Cunha-Reis, Diana. "Profound alterations in hippocampal lipid rafts follow in vitro epileptiform activity, hypoxia and oxygen-glucose deprivation". Trabalho apresentado em Neuronus 2022 Meeting, Krakow, 2022. Publicado Gil, Marta; Caulino-Rocha, Ana; Beatriz Vila-Verde; Diana Reis-Borges; Carlos Nascimento; Cunha-Reis, Diana; Vila-Verde, Beatriz; et al. "Altered synaptic physiology and impaired cognition, response to novelty and motor behavior in a rodent model of accelerated aging". Trabalho apresentado em Neuronus 2022 Meeting, Krakow, 2022. Publicado Gil, Marta; Bento, Marta; Rodrigues, Nádia Carolina; Silva-Cruz, Armando (0000-0002-4403-622X); Cunha-Reis, Diana. "Postweaning development shifts endogenous VPAC1 modulation of LTP induced by theta-burst stimulation". Trabalho apresentado em Europhysiology 2022, Copenhagen, 2022. Publicado Cunha-Reis, Diana. "Mismatch novelty exploration training shaping of hippocampal synaptic plasticity and cognition and the role of disinhibition and VIP expressing interneurons". Trabalho apresentado em 55th Annual Congress of SBFIS (Sociedade Brasileira de Fisiologia) - Joint meeting with SPFis, Online, 2020. Publicado Caulino-Rocha, Ana; Aidil-Carvalho, Fatima; Ribeiro, JA; Cunha-Reis, Diana. "Influence of novelty exploration training on modulation of hippocampal synaptic plasticity by endogenous VIP acting on VPAC1 receptors.". Trabalho apresentado em 55th Annual Congress of SBFIS (Sociedade Brasileira de Fisiologia) - Joint meeting with SPFis, Online, 2020. Publicado José Diogo Carvalho-Rosa; Rodrigues, Nádia Carolina Amorim; Cunha-Reis, Diana; Carvalho-Rosa, JD; Rodrigues, NC. "Endogenous VIP VPAC1 receptor activation during ictal and interictal-like activity induced in vitro by bicuculine and 0-Mg2+ modulates subsequent LTP expression in the rat hippocampus". Trabalho apresentado em XVI Meeting of the Portuguese Society for Neuroscience (SPN2019), Lisboa, 2019. Publicado Beatriz Vila-Verde; Diana Reis-Borges; Carlos Nascimento; Diana Cunha-Reis; Cunha-Reis, Diana. "Impaired response to novelty and motor behaviour in the D-Gal rat model of accelerated aging.". Trabalho apresentado em Front. Cell. Neurosci. Conference Abstract: XVI Meeting of the Portuguese Society for Neuroscience (SPN2019), Lisboa, 2019. Publicado • 10.3389/conf.fncel.2019.01.00002 Cunha-Reis, D.; Ribeiro, J. A.; Sebastiao, A. M.. "VIP modulates K+-evoked H-3 -GABA release from hippocampal synaptosomes through activation of both VPAC1 and VPAC2 receptors". 2004. Cunha-Reis, Diana; Sebastiao, Ana M.; Ribeiro, Joaquim A.. "Adenosine modulates the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus". Trabalho apresentado em British Pharmacological Society Winter meeting 2000, Cambridge, 2000. Cunha-Reis, D. L.; Sebastiao, A. M.; Ribeiro, J. A.. "Transduction mechanisms involved in the action of VIP in the rat hippocampus". 2000.
Artigo em revista	Marta Gil; Ana Caulino-Rocha; Marta Bento; Nádia C. Rodrigues; Armando Silva-Cruz; Joaquim A. Ribeiro; Diana Cunha-Reis. "Postweaning Development Influences Endogenous VPAC1 Modulation of LTP Induced by Theta-Burst Stimulation: A Link to Maturation of the Hippocampal GABAergic System". Biomolecules (2024): https://doi.org/10.3390/biom14030379. 10.3390/biom14030379 Nascimento, Carlos; Guerreiro-Pinto, Vasco; Pawlak, Seweryn; Caulino-Rocha, Ana; Amat-Garcia, Laia; Cunha-Reis, Diana. "Impaired Response to Mismatch Novelty in the Li2+-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs". Biomedicines 12 3 (2024): 631. http://dx.doi.org/10.3390/biomedicines12030631. 10.3390/biomedicines12030631 Marta Bento; Caulino-Rocha, Ana; Joaquim A Ribeiro; Cunha-Reis, Diana. Autor correspondente: Cunha-Reis, Diana. "A decrease in GluA1 basal phosphorylation levels may contribute to the enhancement in LTP induced by theta-burst stimulation along postweaning development". IBRO Neuroscience Reports 15 (2023): S304-S304. Publicado Cunha-Reis, Diana; Vaz, Sandra Henriques; Correia-de-Sá, Paulo. "Editorial: Cellular and molecular targets in epileptogenesis focusing on disease prevention". Frontiers in Cellular Neuroscience 17 (2023): http://dx.doi.org/10.3389/fncel.2023.1251038. 10.3389/fncel.2023.1251038 José D. Carvalho-Rosa; Nádia C. Rodrigues; Armando Silva-Cruz; Sandra H. Vaz; Diana Cunha-Reis. "Epileptiform activity influences theta-burst induced LTP in the adult hippocampus: a role for synaptic lipid raft disruption in early metaplasticity?". Frontiers in Cellular Neuroscience 17 (2023): http://dx.doi.org/10.3389/fncel.2023.1117697. 10.3389/fncel.2023.1117697 Marta Bento; Ana Caulino-Rocha; Joaquim Ribeiro; Diana Cunha-Reis. "A DECREASE IN GLUA1 BASAL PHOSPHORYLATION LEVELS MAY CONTRIBUTE TO THE ENHANCEMENT IN LTP INDUCED BY THETA-BURST STIMULATION ALONG POSTWEANING DEVELOPMENT". IBRO Neuroscience Reports (2023): https://publons.com/wos-op/publon/66800618/. 10.1016/J.IBNEUR.2023.08.544 André Serpa; Marta Bento; Ana Caulino-Rocha; Seweryn Pawlak; Diana Cunha-Reis. "Opposing reduced VPAC1 and enhanced VPAC2 VIP receptors in the hippocampus of the Li2+-pilocarpine rat model of temporal lobe epilepsy". Neurochemistry International 158 (2022): 105383-105383. https://doi.org/10.1016/j.neuint.2022.105383. 10.1016/j.neuint.2022.105383 Ana Caulino-Rocha; Nádia Carolina Rodrigues; Joaquim Alexandre Ribeiro; Diana Cunha-Reis. "Endogenous VIP VPAC1 Receptor Activation Modulates Hippocampal Theta Burst Induced LTP: Transduction Pathways and GABAergic Mechanisms". Biology 11 5 (2022): 627-627. https://doi.org/10.3390/biology11050627. 10.3390/biology11050627 Rodrigues, Nádia Carolina; Silva-Cruz, Armando; Caulino-Rocha, Ana; Bento-Oliveira, Andreia; Alexandre Ribeiro, Joaquim. "Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited". European Journal of Neuroscience 54 4 (2021): 5272-5292. http://dx.doi.org/10.1111/ejn.15390. 10.1111/ejn.15390 Cunha-Reis, Diana. "Corrigendum: VIP Modulation of Hippocampal Synaptic Plasticity: A Role for VIP Receptors as Therapeutic Targets in Cognitive Decline and Mesial Temporal Lobe Epilepsy". Frontiers in Cellular Neuroscience 15 (2021): http://dx.doi.org/10.3389/fncel.2021.691978. 10.3389/fncel.2021.691978 D. Cunha-Reis; A. Caulino-Rocha; P. Correia-de-Sá. "VIPergic neuroprotection in epileptogenesis: challenges and opportunities". Pharmacological Research 164 (2021): 105356-105356. https://doi.org/10.1016/j.phrs.2020.105356. Publicado • 10.1016/j.phrs.2020.105356 Cunha-Reis, Diana; Caulino-Rocha, Ana. "VIP Modulation of Hippocampal Synaptic Plasticity: A Role for VIP Receptors as Therapeutic Targets in Cognitive Decline and Mesial Temporal Lobe Epilepsy". Frontiers in Cellular Neuroscience 14 (2020): http://dx.doi.org/10.3389/fncel.2020.00153. Acesso aberto • 10.3389/fncel.2020.00153 Diana Cunha-Reis; Joaquim Alexandre Ribeiro; Rodrigo F M de Almeida; Ana M Sebastião. "VPAC1 and VPAC2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways". British Journal of Pharmacology (2017): https://doi.org/10.1111/bph.14051. 10.1111/bph.14051 Aidil-Carvalho, M.F.; Carmo, A.J.S.; Ribeiro, J.A.; Cunha-Reis, D.. "Mismatch novelty exploration training enhances hippocampal synaptic plasticity: A tool for cognitive stimulation?". Neurobiology of Learning and Memory 145 (2017): 240-250. http://dx.doi.org/10.1016/j.nlm.2017.09.004. Publicado • 10.1016/j.nlm.2017.09.004 Cunha-Reis, Diana; Aidil-Carvalho, Maria de Fatima; Ribeiro, Joaquim A.. "Endogenous inhibition of hippocampal LTD and depotentiation by vasoactive intestinal peptide VPAC1receptors". Hippocampus 24 11 (2014): 1353-1363. http://dx.doi.org/10.1002/hipo.22316. Publicado • 10.1002/hipo.22316 Cunha-Reis, Diana; Ribeiro, Joaquim A.; Sebastião, Ana M.. "A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+-evoked [3H]-GABA release from rat hippocampal nerve terminals". Neuroscience Letters 430 3 (2008): 207-212. http://dx.doi.org/10.1016/j.neulet.2007.10.037. Publicado • 10.1016/j.neulet.2007.10.037 Cunha-Reis, D.; Fontinha, B.M.; Ribeiro, J.A.; Sebastião, A.M.. "Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus". Neuropharmacology 52 2 (2007): 313-320. http://dx.doi.org/10.1016/j.neuropharm.2006.08.003. 10.1016/j.neuropharm.2006.08.003 Cunha-Reis, Diana; Fontinha, B. M.; Ribeiro, Joaquim A.; Sebastião, Ana M. "Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus". (2007): http://hdl.handle.net/10451/8275. http://dx.doi.org/10.1016/j.neuropharm.2006.08.003 CUNHA-REIS, D.. "VPAC2 Receptor Activation Mediates VIP Enhancement of Population Spikes in the CA1 Area of the Hippocampus". Annals of the New York Academy of Sciences 1070 1 (2006): 210-214. http://dx.doi.org/10.1196/annals.1317.016. 10.1196/annals.1317.016 Cunha-Reis, Diana; Ribeiro, Joaquim A.; Sebastião, Ana M. "VPAC2 receptor activation mediates VIP enhancement of population spikes in the CA1 area of the hippocampus". (2006): http://hdl.handle.net/10451/7598. http://dx.doi.org/10.1196/annals.1317.016 Cunha-Reis, Diana; Ribeiro, Joaquim Alexandre; Sebastião, Ana M.. "VIP enhances synaptic transmission to hippocampal CA1 pyramidal cells through activation of both VPAC1 and VPAC2 receptors". Brain Research 1049 1 (2005): 52-60. http://dx.doi.org/10.1016/j.brainres.2005.04.077. 10.1016/j.brainres.2005.04.077 Cunha-Reis, Diana; Sebastião, Ana M; Wirkner, Kerstin; Illes, Peter; Ribeiro, Joaquim Alexandre. "VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells". British Journal of Pharmacology 143 6 (2004): 733-744. http://dx.doi.org/10.1038/sj.bjp.0705989. 10.1038/sj.bjp.0705989 Ribeiro, J. Alexandre; Cunha-Reis, Diana; Lopes, Luisa V.; Coelho, Joana E.; Costenla, Ana Rita; Correia-de-Sá, Paulo; Cunha, Rodrigo A.; de Mendonça, Alexandre; Sebastião, Ana M.. "Adenosine receptor interactions in the hippocampus". Drug Development Research 52 1-2 (2001): 337-345. http://dx.doi.org/10.1002/ddr.1132. 10.1002/ddr.1132
Capítulo de livro	Cunha-Reis, Diana. "Zinco: Senhor zinco, proteja essas sinapses!". In Os Elementos em Ciências - Uma viagem pela Tabela Periódica, editado por Ana Mourato; Ana Paula Carvalho; Filomena Martins; Teresa Pamplona. Lisboa, Portugal: Ciências ULisboa, 2020. Publicado
Poster em conferência	Carvalho-Rosa, JD; Rodrigues, NC; Cunha-Reis, Diana. "VPAC1 receptor activation by endogenous VIP during interictal-like activity induced in vitro by 0-Mg2+ influences subsequent LTP expression in the rat hippocampus". Trabalho apresentado em 12 FENS Forum of Neuroscience ¿ Virtual Forum, 2020. Caulino-Rocha, Ana; Nádia C. Rodrigues; Andreia Oliveira; Joaquim A Ribeiro; Cunha-Reis, Diana. "Molecular pathways involved in VIP inhibition of LTP in the CA1 area of the hippocampus". Trabalho apresentado em FENS 2020, 2020. Bento-Oliveira, Andreia; Pereira, Pedro; de Almeida, Rodrigo F.M. ; Amaro-Leal, Ângela; Cunha-Reis, Diana. "Altered synaptic plasticity and lipid raft composition in a rat model of MTLE". Trabalho apresentado em Workshop on Integrative approaches in neurodegeneration, 2018. Leal, Ângela; Cunha-Reis, Diana; Amaro-Leal, Ângela; Amaro-Leal, A; Rocha, I; Cunha-Reis, Diana. "Training in novelty exploration tasks prevents cognitive decline in a rat model of TLE (Poster A-778-0003-00425)". Trabalho apresentado em 12th European Congress on Epileptology (Prague, Czech Republic), 2016. 10.1111/epi.13609 Cunha-Reis, D; Rosa, N; Amaro-Leal, A; Nunes-da-Silva, C; Rocha, I. "Impaired spatial memory and response to novelty in a rat model of metabolic syndrome. ". 2014. Amaro-Leal, Ângela; Cunha-Reis, Diana. "Preventing epileptogenesis, cognitive decline and sudden death in a rat model of TLE: training in novelty exploration tasks". Trabalho apresentado em VII PhD Students Meeting CAML (Portugal), 2013. Leal, Ângela; Cunha-Reis, Diana. "Cognitive impact of repeated exposure to novel spatial arrangement of objects (Poster 7)". Trabalho apresentado em SPE: 10º Congresso Nacional de Etiologia (Portugal), 2013. Cunha-Reis, Diana. "Contribution of endogenous VIP VPAC1 receptor activation during hypoxia and interictal-like activity induced in vitro by 0-Mg2+ to subsequent changes in LTP expression in the rat hippocampus". Trabalho apresentado em IUPS 2013, 2013. Amaro-Leal, A; Carmo, AJS; Rocha, I; Cunha-Reis, D; Leal, Ângela; Cunha-Reis, Diana. "Repeated exposure to novel spatial arrangement of objects: impact on hippocampal-dependent learning and synaptic plasticity.". Trabalho apresentado em IUPS 2013, 2013. 10.5220/0001051702640268 Cunha-Reis, Diana; Aidil-Carvalho, Fatima; Ribeiro, Joaquim Alexandre. "Endogenous inhibition of hippocampal LTD and depotentiation by vasoactive intestinal peptide VPAC1 receptors.". Trabalho apresentado em 8th FENS Forum of European Neuroscience – Fens 2012, 2012. 10.1002/hipo.22316 Carmo, AJ; Amaro-Leal, A; Rocha, I; Cunha-Reis, D. "Hippocampal-dependent learning and synaptic plasticity in rats experiencing repeated exposure to novel spatial arrangement of objects.". Trabalho apresentado em 8th Forum of European Neuroscience, 2012.
Pré-impressão	C Nascimento; V Guerreiro-Pinto; S Pawlak; A Caulino-Rocha; L Amat-Garcia; D Cunha-Reis. "Impaired response to mismatch novelty in the Li2+-pilocarpine rat model of TLE: correlation with hippocampal monoaminergic inputs". 2024. https://doi.org/10.1101/2024.02.07.579299. 10.1101/2024.02.07.579299 Marta Gil; Ana Caulino-Rocha; Marta Bento; Nadia Carolina Rodrigues; Armando Silva-Cruz; Joaquim Alexandre Ribeiro; Diana Cunha-reis. "Postweaning development influences endogenous VPAC1 modulation of LTP induced by theta-burst stimulation: a link to maturation of the hippocampal GABAergic system?". 2024. https://doi.org/10.1101/2024.02.18.580862. 10.1101/2024.02.18.580862 Fatima Aidil-Carvalho; Ana Caulino-Rocha; Joaquim A Ribeiro; Diana Cunha-Reis. "Mismatch novelty exploration training impairs VPAC1 receptor mediated modulation of hippocampal synaptic plasticity by endogenous VIP". 2022. https://doi.org/10.1101/2022.12.21.521348. 10.1101/2022.12.21.521348 JD Carvalho-Rosa; NC Rodrigues; A Silva-Cruz; SH Vaz; D Cunha-Reis. "Epileptiform activity influences theta-burst induced LTP in the adult hippocampus: a role for lipid raft dynamics in early metaplasticity". 2022. https://doi.org/10.1101/2022.12.06.519267. 10.1101/2022.12.06.519267 Rodrigues, NC; Silva-Cruz, A; Caulino-Rocha, A; Bento-Oliveira, A; Ribeiro, JA; Cunha-Reis, D. "Cellular and molecular mechanisms involved in LTP induced by mild theta-burst stimulation in hippocampal slices from young male rats: from weaning to adulthood". 2021. https://doi.org/10.1101/2021.04.19.440440. 10.1101/2021.04.19.440440 Rodrigues, Nadia; Caulino-Rocha, Ana; Ribeiro, Joaquim; Cunha-Reis, Diana. "Tonic activation of VPAC1 receptors by VIP modulates theta-burst induced LTP in the hippocampus: transduction pathways and GABAergic mechanisms.". 2021. http://dx.doi.org/10.22541/au.161787961.10433709/v1. 10.22541/au.161787961.10433709/v1
Resumo em conferência	Caulino-Rocha, Ana; Carlos Nascimento; Amaro-Leal, Ângela; Serpa, Andre; Cunha-Reis, Diana. "Impaired response to mismatch novelty in the Li2+-pilocarpine rat model of TLE: correlation with synaptic remodeling and hippocampal monoamines. Epilepsia, 64(S2), 227-228 .". Trabalho apresentado em 35th International Epilepsy Congress, Dublin, 2023. Publicado Carmo, A. J.; Cunha-Reis, D.. "Evidence of emergent patterns in GluR1 phosphorylation in theta-burst LTP experiments with data mining tools". Trabalho apresentado em Amino Acids (Journal) PROCEEDINGS 12th FORUM OF AMINO ACID, PEPTIDE AND PROTEIN RESEARCH, 1st–5th AUG, BEIJING, 2011. Publicado Cunha-Reis, D.; Carmo, A. J.. "Correlation of VIP VPAC(1) modulation of GluR1 phosphorylation and inhibition of protein kinases in theta-burst LTP experiments with data mining tools". Trabalho apresentado em Amino Acids (Journal) PROCEEDINGS 12th FORUM OF AMINO ACID, PEPTIDE AND PROTEIN RESEARCH, 1st–5th AUG, Beijing, 2011. Publicado Cunha-Reis, Diana; Rodrigues, Nadia C.; Ribeiro, Joaquim A.. "On the cellular and molecular pathways involved in the inhibition of LTP in the CA1 area of the hippocampus". Trabalho apresentado em J Mol Neurosci PROCEEDINGS OF THE 9th INTERNATIONAL SYMPOSIUM ON VIP, PACAP AND RELATED PEPTIDES, 5th -8th OCTOBER 2009, Kagoshima, 2009. Publicado Cunha-Reis, Diana; Ribeiro, Joaquim A.; Sebastiao, Ana M.. "On the pathways involved in VPAC1 and VPAC2 receptor mediated modulation of GABA release from hippocampal synaptosomes". Trabalho apresentado em J Neurochem - PROCEEDINGS OF THE ISN-ESN 2005 MEETING, 21ST-26TH AUGUST 2005, Innsbruck, 2005. Publicado
Tese / Dissertação	"Changes in synaptic plasticity and lipid raft composition in the hippocampus induced in vitro by hypoxia and oxygen-glucose deprivation". Licenciatura, Universitat de Girona, 2022. "Changes in synaptic plasticity and lipid raft composition in the hippocampus in different ages and gender, induced in vitro by epileptiform activity and neuroprotective role of VPAC1 VIP receptor antagonists". Mestrado, Universidade de Lisboa Faculdade de Ciências, 2021. http://hdl.handle.net/10451/51710. Rosa, José Diogo Carvalho. "Alterações da plasticidade sináptica e da composição de jangadas lipídicas no hipocampo em diferentes idades e sexos assim como induzidas in vitro por atividade epiletiforme e o papel neuroprotetor dos recetores VPAC1 para o VIP". Mestrado, 2021. http://hdl.handle.net/10451/51710. Araújo, Margarida Nóbrega Campos de Freitas. "Investigating the mechanisms of synaptic dysfunction in late-onset Alzheimer’s disease". Mestrado, 2020. http://hdl.handle.net/10451/48747. Oliveira, Andreia Bento de. "Changes in synaptic plasticity and lipid raft composition in a rat model of temporal lobe epilepsy". Mestrado, 2018. http://hdl.handle.net/10451/37090. Martins, Maria Luísa Casanova Alves. "Contribuição da actividade física para a recuperação na epilepsia". Mestrado, 2014. http://hdl.handle.net/10437/5861. Remígio, Ana Maria Duarte. "Alterações cardiovasculares na epilepsia do lobo temporal". Mestrado, 2014. http://hdl.handle.net/10437/5860. Cruz, Armando Dulcídio da Silva. "The influence of epilepsy in synaptic plasticity in the hippocampus: neuroprotective role of VIP and its receptors". Mestrado, 2010. http://hdl.handle.net/10451/4546. Rodrigues, Nádia Carolina Amorim. "Vias de transdução envolvidas no efeito do VIP na LTP na área CA1 do hipocampo". Mestrado, 2009. http://hdl.handle.net/10316/28668. Cunha-Reis, Diana. "Vasoactive intestinal peptide (VIP) increases GABAergic transmission to interneurones and pyramidal cells in the hippocampus: consequences for pyramidal cell activity and modulation by endogenous adenosine". Doutoramento, Universidade de Lisboa Faculdade de Medicina, 2007.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2024/02/11	Alterations in GluA1 and GluN1 basal phosphorylation levels: impact on TBS-induced LTP enhancement along postweaning development?	54th Reunion of The Portuguese Pharmacological Society Universidade Nova de Lisboa (Lisboa, Portugal)
2023/05/30	Invited lecture - Dynamic changes in VIP VPAC1 and VPAC2 receptor expression during post-weaning development and in epilepsy: relevance for synaptic plasticity’, Spring Hippocampal Research Conference, 28th May-2nd June, 2023, Verona, Italy.	Spring Hippocampal Research Conference Organizing committee (Verona, Itália)
2022/02/11	Postweaning development influences endogenous VPAC1 modulation of LTP induced by theta-burst stimulation	52nd Reunion of The Portuguese Pharmacological Society, Porto, Portugal, 9th -11th February 2022 Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2021/10/13	Metaplasticity following brain hyperactivity and brief hypoxia: significance for endogenous neuroprotection	Simpósio Brasileiro-Ibérico de Fisiologia – ‘Cellular and molecular pathways controlling homeostasis by the brain’, representing the Portuguese Society of Physiology held at the 56º Congresso Annual da SBFis (Sociedade Brasileira de Fisiologia). Sociedade Brasileira de Fisiologia (Online, Brasil)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2022/02/01 - 2022/07/17	Changes in synaptic plasticity and lipid raft composition induced in vitro by hypoxia and oxygen-glucose deprivation Orientador de Laia Amat Garcia	Biotechnology (Licenciatura/Bacharelato) Universitat de Girona Departament de Biologia, Espanha
2019/09/15 - 2021/12/03	Changes in synaptic plasticity, lipid raft composition in the hippocampus in different ages and gender, induced in vitro by epileptiform activity and neuroprotective role of VPAC1 VIP receptor antagonists Orientador de José Diogo Carvalho Rosa	Biologia Humana e Ambiente (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2017/09/01 - 2019/01/31	Changes in synaptic plasticity and lipid raft composition in a rat model of temporal lobe epilepsy MSc thesis Andreia Bento-Oliveira Orientador de Andreia Bento de Oliveira	Bioquímica (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2018/07/01 - 2018/08/05	Supervision of an IASTE (International Association for the Exchange of Students for Technical Experience) internship of Tania Azem, BSc student in Chemistry (Biology minor, Université Pierre et Marie Curie/Sorbonne Universités) Orientador	Universidade de Lisboa Faculdade de Ciências, Portugal
2013/03/01 - 2016/09/30	New approaches for preventing epileptogenesis, cognitive decline and sudden death in a rat model of temporal lobe epilepsy: training in novelty exploration tasks and the role of VIP VPAC1 receptors Orientador de Ângela Raquel Amaro Leal	Neurociências (Doutoramento) Universidade de Lisboa Faculdade de Medicina, Portugal
2014 - 2014	Deficiências cognitivas associadas à diabetes mellitus Orientador de Mariam Iqbal Haji	Ciências farmacêuticas (Mestrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2014 - 2014	Alterações Cardiovasculares na Epilepsia do Lobo Temporal Orientador de Ana Maria Remígio	Mestrado Integrado Ciências Farmacêuticas (Mestrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2014 - 2014	Contribuição da Actividade Física para a Recuperação na Epilepsia Orientador de Maria Luísa Casanova Alves Martins	Mestrado Integrado Ciências Farmacêuticas (Mestrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012 - 2014	Evaluation of the impact of novelty exploration training tasks on spatial memory in the rat: a primer for potential use in preventing cognitive decline in CNS Orientador de Ângela Raquel Amaro Leal	Neurociências (Mestrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2009 - 2010	The Influence of epilepsy in synaptic plasticity in the hippocampus: Neuroprotective role of VIP and its receptors	Bioquímica (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2008 - 2009	Vias de transdução envolvidas no efeito do VIP na LTP na área CA1 do hipocampo Orientador de Nádia Carolina Amorim Rodrigues	Biologia Celular e Molecular (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007/10/01 - 2008/12/31	Modulation of LTD and depotentiation by VIP receptors and novelty exploration training Orientador	Neurociências (Mestrado) Universidade de Lisboa Faculdade de Medicina, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2023/07/24 - 2023/07/28	Coordinator of 'Ser Cientista' research activities under the project ¿Surviving an epileptic crisis¿, held from 24-28th July 2023 at the Epilepsy and Aging Lab, BioISI ¿ Biosystems and Integrative Sciences Institute, Ciências, ULisboa. (2023) Outro (Outra)	Universidade de Lisboa Faculdade de Ciências, Portugal
2022/02 - 2022/03	March 2022 - Organizer and participant of the Brain Awareness Week 2019 activities that have taken place from 18th march 2022 at BioISI - Biosystems and Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa. Lectures and practical activities involved over 6 BioISI researchers and colaborators in the fields of Biology, Biochemistry, Biomedical Engineering and Informatics. (http://bioisi.pt/bioisi-hosted-a-high-school-students-visit-within-the-brain-awareness-week). (2022/03/18 - 2022/03/18) Oficina (workshop) (Presidente da Comissão Organizadora)
2019/02/01 - 2019/03/17	February to March 2019 - Organizer and participant of the Brain Awareness Week 2019 activities that have taken place from 11-17th march 2019 at BioISI - Biosystems and Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa. Lectures and practical activities involved over 15 BioISI researchers and colaborators in the fields of Biology, Biochemistry, Biomedical Engineering and Informatics. (http://bioisi.pt/newsletter-april/). (2019/03/11 - 2019/03/17) Outro (Presidente da Comissão Organizadora)	Universidade de Lisboa Faculdade de Ciências, Portugal
2011/07/11 - 2011/07/19	Local support to the organizing committee of the 2nd EFAS School (School of Autonomic Neuroscience), 16th-19th June 2011 IMM Lisbon Portugal (2011/07/11 - 2011/07/19) Oficina (workshop) (Outra)	Universidade de Lisboa Faculdade de Medicina, Portugal
2010/12/13 - 2010/12/15	Local support to the organizing committee of the 4th Portuguese Mass Spectrometry Meeting, 13th-15th December 2010, FCUL, Portugal (2010/12/11 - 2010/12/13) Encontro (Outra)	Universidade de Lisboa Faculdade de Ciências, Portugal
2008/01/01 - 2010/06/30	Weekly Neuroscience Seminars at the Neuroscience and Pharmacology Unit, Institute of Molecular Medicine, University of Lisbon (2008/01/01 - 2010/06/30) Encontro (Membro da Comissão Organizadora)	Instituto de Medicina Molecular, Portugal
2008/03 - 2008/12	39th Annual meeting of the Portuguese Pharmacological Society (2008/12/03 - 2008/12/05) Congresso (Membro da Comissão Organizadora)	Sociedade Portuguesa de Neurociências, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2022/11/12 - Atual	Co-chair with Professor Telmo Pereira (in substitution of Prof. Ana Fernandes) of the Podium Session for selected meeting presentations at the 2nd International Meeting of the Portuguese Society of Physiology (Physioma 2022), ESTEC, Coimbra, Portugal Conferência	2nd International Meeting of the Portuguese Society of Physiology (Physioma 2022)
2017/05/31 - Atual	Poster communication - Cunha-Reis D (2017) Role of endogenous VIP VPAC1 receptor activation during hypoxia and interictal-like activity induced in vitro by 0-Mg2+ in LTP expression in the rat hippocampus. Encontro	CQB-Day 2017, CQB, DQB, FCUL Universidade de Lisboa Faculdade de Ciências, Portugal
2024/02/09 - 2024/02/11	Co-chair with Professor Jorge Oliveira of symposium Session XIX at the 54th Reunion of The Portuguese Pharmacological Society held at Lisbon, Portugal, 7th -9th February 2024. Conferência	54th Reunion of The Portuguese Pharmacological Society Universidade Nova de Lisboa, Portugal
2020/07/11 - 2020/07/15	Poster communication - Caulino-Rocha A, Rodrigues NC, Bento Oliveira A, Ribeiro JA, Cunha-Reis D (2020) Molecular pathways involved in VIP inhibition of LTP in the CA1 area of the hippocampus. Communication to the 12th FENS Forum of European Neuroscience - Fens 2020, Glasgow, UK, 11th -15th July 2020. Congresso	12th FENS Forum of European Neuroscience – Fens 2020 Federation of European Neuroscience Societies, Bélgica
2020/07/11 - 2020/07/15	Poster communication - Carvalho-Rosa J, Rodrigues NC, Cunha-Reis D (2020) VPAC1 receptor activation by endogenous VIP during interictal-like activity induced in vitro by 0-Mg2+ influences subsequent LTP expression in the rat hippocampus. Communication to the 12th FENS Forum of European Neuroscience - Fens 2020, Glasgow, UK, 11th -15th July 2020. Congresso	12th FENS Forum of European Neuroscience – Fens 2020 Federation of European Neuroscience Societies, Bélgica
2019/10/10 - 2019/10/11	Poster communication - Bento-Oliveira A, Pereira P, Amaro Leal A, Cunha Reis D (2019) Evidence for altered lipid raft composition and synaptic plasticity in a rat model of MTLE. Communication to the 1st International Meeting of The Portuguese Society Of Physiology - Physioma 2019, Lisbon, Portugal, 10th -11th October 2019. Encontro	Physioma 2019 Sociedade Portuguesa de Fisiologia, Portugal
2019/02/04 - 2019/02/04	Contributing to discussion on strategies to fund human resources in science . Conferência	How to support human resources and careers in science? Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2018/12/17 - 2018/12/17	Speaker at Round Table - As carreiras científicas em Portugal: debate com investigadores, docentes e gestores de ciência' at the meeting 'Universidade e trabalho científico' held 17 de Dezembro, FCSH, Univ. Nova de Lisboa, Portugal. Mesa-redonda	Universidade e trabalho científico
2018/06/21 - 2018/06/23	Poster communication - Bento-Oliveira A, Pereira P, de Almeida RF, Amaro-Leal A Cunha-Reis, D (2018). Altered synaptic plasticity and lipid raft composition in a rat model of MTLE. Oficina (workshop)	Workshop on Integrative Approaches in Neurodegeneration Universidade de Lisboa Faculdade de Ciências, Portugal
2018/06/21 - 2018/06/23	Poster communication - Nascimento C, Pereira P, Tavares C, Gonçalves-Rosa N Esteves-Coelho J, Cunha-Reis, D (2018). Impaired response to novelty and motor behaviour in a rat model of accelerated aging. Oficina (workshop)	Workshop on Integrative Approaches in Neurodegeneration Universidade de Lisboa Faculdade de Ciências, Portugal
2018/06/21 - 2018/06/23	Poster communication - Bento-Oliveira A, Pereira P, de Almeida RF, Amaro-Leal A Cunha-Reis, D (2018). Altered synaptic plasticity and lipid raft composition in a rat model of MTLE. Communication to the Workshop on Integrative Approaches in Neurodegeneration, FCUL, Lisboa, Portugal, 21st -23rd June 2018. Oficina (workshop)	Workshop on Integrative Approaches in Neurodegeneration Universidade de Lisboa Faculdade de Ciências, Portugal
2018/02/05 - 2018/02/07	Oral Communication - Bento-Oliveira A, Rodrigues NC, Ribeiro JA, de Almeida RF, Cunha-Reis, D (2018). Changes in AMPA receptors GluA1 subunit and Kv4.2 phosphorylation in rat hippocampus. Encontro	48th REUNION OF THE PORTUGUESE PHARMACOLOGICAL SOCIETY

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2021/12/03	Changes in synaptic plasticity, lipid raft composition in the hippocampus in different ages and gender, induced in vitro by epileptiform activity and neuroprotective role of VPAC1 VIP receptor antagonists Orientador	José Diogo Carvalho Rosa (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2021/09/10	Effect of cannabidiol on synchronous GABA and glutamate release from resting hippocampal nerve terminals Arguente principal	Laura Pereira Marinho (Outro) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/11/22	THE EFFECT OF CANNABIDIOL IN THE IMMATURE BRAIN Arguente principal	Ana Veiga Caulino Rocha (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/01	Changes in synaptic plasticity and lipid raft composition in a rat model of temporal lobe epilepsy Orientador	Andreia Bento de Oliveira (Mestrado) Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Arbitragem científica em conferência

	Nome da conferência	Local da conferência
2023/11 - Atual	3rd International Meeting of the Portuguese Society of Physiology (Physioma 2024)	Faculdade de Medicina da Universidade do Porto
2023/11 - Atual	FEPS-Spanish Society for Physiological Sciences (SECF) meeting	Spanish Society for Physiological Sciences
2022/05 - 2022/11/18	2nd International Congress of the Portuguese Society of Physiology	Sociedade Portuguesa de Fisiologia
2003/12/01 - 2014/01/31	FENS Forum 2014	Lisboa, Portugal

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2022/11/10 - Atual	Frontiers in Cellular Neuroscience	Frontiers Media S.A.
2022/09/05 - Atual	Editor of special issue in Biomedicines - Drugs Targeting the Disease Progression, Cognitive Impairment, Anxiety and Other Co-Morbidities in Epilepsy: From Bench to Bedside (2227-9059)	MDPI
2021/07 - 2023/06/30	Frontiers in Cellular Neuroscience Special issue: Cellular and Molecular Targets In Epileptogenesis Focusing on Disease Prevention	Frontiers
2018/01 - 2018/09	Experimental Gerontology (0531-5565)	Elsevier
2013 - 2013	Journal of Zhejiang University SCIENCE B (1862-1783)	Zhejiang University Press

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2023/10 - 2023/12	Evaluator of the proposals submitted to the 2023 call of the of the Marie Sklodowska Curie Actions Postdoctoral Fellowships H2022 MSCA PF 2023 Avaliador	Research Executive Agency, Bélgica	Horizon 2020
2022/10/07 - 2022/11/22	Evaluator of the proposals submitted to the 2022 call of the of the Marie Sklodowska Curie Actions Postdoctoral Fellowships H2022 MSCA PF 2022. Avaliador	European Commission, Bélgica	EU Framework Programme for Research and Innovation Excellent Science
2022/10/04 - 2022/10/10	Scientific evaluator of the abstracts submitted to the 2nd International Conference of the Portuguese Physiology Society Avaliador	Sociedade Portuguesa de Fisiologia, Portugal
2021/11/01 - 2021/12/21	Evaluator of the proposals submitted to the 2021 call of the of the Marie Sklodowska Curie Actions Postdoctoral Fellowships H2021 MSCA PF 2021. Avaliador	European Commission, Bélgica	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2020/10/02 - 2020/12/04	Evaluation of the proposals submitted to the Marie Sklodowska-Curie Individual Fellowships H2020-MSCA-IF-2020 Avaliador	Research Executive Agency, Bélgica	European Commission
2019/10/01 - 2019/12/05	Evaluator of the proposals submitted to the Marie Sklodowska-Curie Individual Fellowships H2020-MSCA-IF-2019 Avaliador	Research Executive Agency, Bélgica	European Commission

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2019/09/01 - 2021/07/31	Physiology lecturer and course responsible, Biochemistry BSc FCUL by invitation.	Biochemistry (Licenciatura)	Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2014	Human Physiology I (Pharmacological Sciences integrated MSc)	Fisiologia Humana I (Mestrado integrado)	Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012 - 2014	Physiology I (Nutrition degree)	Fisiologia I (Licenciatura)	Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012 - 2013	Human Physiology II	Fisiologia humana II (Mestrado integrado)	Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012 - 2013	Physiology II (Nutrition degree)	Fisiologia II (Mestrado integrado)	Universidade Lusófona de Humanidades e Tecnologias, Portugal

Entrevista / Programa (rádio / tv)

	Programa	Tema
2008/03/18 - Atual	TV Ciência - Neurociências	Comunicação entre neurónios pode ser chave do segredo de algumas doenças

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2020 - 2020	Referee of a manuscript (review paper) submitted to Biology (2020)	Multidisciplinary Digital Publishing Institute AG, Suiça
2019 - 2019	Referee of a manuscript submitted to Frontiers in Cellular Neuroscience (2019)	Frontiers Media SA, Suiça

Revisão ad hoc de artigos em revista

	Nome da revista (ISSN)	Editora
2023 - 2023	Neuroscience Letters	Elsevier
2023 - 2023	Frontiers in Cellular Neuroscience	Frontiers Media
2022/09 - 2022/09	Neural Regeneration Research (1876-7958)	Wolters Kluwer
2022/09 - 2022/09	Frontiers in Neural Circuits (1970-5565)	Frontiers Media S.A.
2022/07 - 2022/08	International Journal of Molecular Sciences ( 1422-0067)	MDPI
2022/05 - 2022/05	International Journal of Molecular Sciences ( 1422-0067)	MDPI
2022/04 - 2022/05	Biomedicines (2227-9059)	MDPI
2022/01/24 - 2022/02/07	International Journal of Environmental Research and Public Health	MDPI
2021 - 2021	International Journal of Molecular Sciences	MDPI
2021 - 2021	Journal of Inflammation Research	Dove Press
2020 - 2020	Biology	MDPI
2019 - 2019	Frontiers in Cellular Neuroscience	Frontiers

Tutoria

	Tópico	Nome do aluno
2023/09/01 - Atual	Altered phosphorylation of hippocampal ionotropic glutamate receptors along post-weaning development	Vasco Guerrero Pinto
2021/11/01 - Atual	Expression of VIP and VIP receptors during postweaning development and in epilepsy	Marta Berardo Pina Santos Bento
2018/09/01 - Atual	Cell culture models of the blood-brain barrier for drug delivery studies to the CNS	Diana Georgete Silva Monteiro Dos Reis Borges
2018/09/01 - Atual	Cell culture models to study in vitro epileptiform activity	Beatriz Pereira e Vila-Verde da Costa e Silva
2021/03/01 - 2021/09/30	Changes in lipid peroxidation and lipid raft composition in a rat model of temporal lobe epilepsy -	Seweryn Pawlak
2021/03/01 - 2021/09/30	Synaptic proteins, VIP receptors and synaptic plasticity in the hippocampus: influence of age and developmental influence -	Marta Gil
2020/09/01 - 2021/06/30	Synaptic proteins, synaptic plasticity and monoaminergic inputs to the hippocampus: influence of mismatch novelty training -	Ana Carolina Duque Queiroz
2014/05/01 - 2015/09/30	Involvement of Kv4.2 channels in endogenous VIP modulation of LTP in the hippocampus	Stivon Silva
2009/07/01 - 2009/07/31	Modulation of hippocampal LTP by VIP receptors	Suzanne Gotham
2009/02/01 - 2009/05/31	VPAC1 receptors in a rat model of MTLE	Ewa Tauroginska Tokarczyk

Distinções

Prémio

2009	Invited speaker congress grant for participation in the meeting ‘9th International Symposium on VIP, PACAP and related peptides’, October 5th-8th 2009, Kagoshima, Japan. VIP-PACAP 2009 Congress Organizers, Japão
2007	Bolsa para participação em Summer School Advanced Course in Neuroplasticity Fundação Calouste Gulbenkian, Portugal
2005	Bolsa participação em congresso VIP-PACAP2005 Fundação Calouste Gulbenkian, Portugal
2004	Bolsa participação em congresso FENS2004 Sociedade Portuguesa de Neurociências, Portugal
2002	Bolsa participação em congresso FENS2002 Sociedade Portuguesa de Neurociências, Portugal
1998	Young Investigator Congress Fellowship

Outra distinção

2021	Invited speaker and seminar coordinator at the 56th Congress of SBFis (Brazilian Society of Physiology) Sociedade Brasileira de Fisiologia, Brasil
2020	Invited speaker at the 55th Annual Congress of SBFIS October 2020 Sociedade Portuguesa de Fisiologia, Portugal
2006	Bolsa participação em congresso FENS2006 Sociedade Portuguesa de Neurociências, Portugal