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Currently, I am a PhD Student in Biology at NOVA School of Science and Technology. My work consists in studying an O-glycan, Sialyl-Tn, as a potential therapeutic target for pancreatic cancer. This work is funded by Fundação para a Ciência e Tecnologia (ref. 2024.05577.BD) and started in November 2024. Previously, I worked as a Quality Control (QC) Assistant at GenIbet Biopharmaceuticals, a contract manufacturing organization based in Oeiras, Portugal, that was recently acquired by Recipharm and integrated in ReciBioPharm business unit. In this work, I participated in the quality control of in-process control samples and final products to be used in early stage drug development, pre-clinical studies and Phase I to Phase III clinical trials, which comprises physico-chemical analyses, microbiological analyses, cell-based assays and nucleic acid analyses according to current Good Manufacturing Practices (cGMP). In addition, I performed other QC routine tasks, such as environmental monitoring of production cleanroom areas and Water for Injection (WFI) sampling and analysis. Furthermore, I had an active role in QC documentation preparation and frequently leaded investigations related to QC deviations. From September 2016 to December 2021, I attended the Integrated Master’s in Biological Engineering at Instituto Superior Técnico of the University of Lisbon. This 5-year course provided me with a solid background on Biology, Mathematics, Physics, Chemistry and Engineering, while having a strong laboratory component. My master’s thesis, entitled “Cardiac Differentiation of Human Induced Pluripotent Cells in Vertical-Wheel Reactors" was carried out at Stem Cell Engineering Research Group (SCERG) of the Institute for Bioengineering and Biosciences (iBB). In this work, I studied the influence of bioprocess parameters in the process costs of the production of cardiomyocytes derived from human induced pluripotent stem cells (hiPSCs) using Vertical-Wheel bioreactors. For this purpose, I developed a bioprocess economic model using Python. In addition, in the laboratory, I studied the impact of different expansion and differentiation medium in the differentiation efficiency of hiPSCs into cardiomyocytes. At the end of this work, I published 1 article, entitled “Bioprocess Economic Modeling: Decision Support Tools for the Development of Stem Cell Therapy Products”, in Bioengineering journal. From March 2022 to June 2022, I have worked in Renova S.A as a laboratory intern, where I used to analyse the mechanical and physical properties of tissue paper and perform the quality control of final products and raw materials (e.g paper pulp). In June 2022, I started working as a QC Trainee at GenIbet Biopharmaceuticals and I was promoted as a QC Assistant in June 2023.
Identificação

Identificação pessoal

Nome completo
INÊS ALEXANDRA BRITES RIBEIRO

Nomes de citação

  • Inês A. B. Ribeiro

Identificadores de autor

Ciência ID
2E10-7E9C-2476
Google Scholar ID
QJbWxSAAAAAJ&hl

Telefones

Telemóvel
  • 914932740 (Pessoal)

Moradas

  • Rua Banda Operária Torrejana Lote 7 2º C, 2350-529 , Torres Novas, Torres Novas, Portugal (Pessoal)

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Outras Ciências da Engenharia e Tecnologias - Outras áreas das Engenharias e Tecnologias

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2016/09/19 - 2021/12/06
Concluído
Biological Engineering (Mestrado integrado)
Especialização em Biological Engineering
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Cardiac Differentiation of Human Induced Pluripotent Cells in Vertical-Wheel Reactors" (TESE/DISSERTAÇÃO)
16/20
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2024/11/01 - Atual PhD Student in Biology Fundação para a Ciência e a Tecnologia, Portugal
Universidade Nova de Lisboa, Portugal
2022/06/14 - 2024/10/04 Quality Control GenIbet Biopharmaceuticals (part of ReciBioPharm), Portugal
GenIbet Biopharmaceuticals (part of ReciBioPharm), Portugal
2022/03/28 - 2022/06/09 Quality Control Renova S.A, Portugal
Renova S.A, Portugal
Projetos

Bolsa

Designação Financiadores
2021/03/01 - 2021/12/06 CARDIOWHEEL - Upscaling the Production of Human Pluripotent Stem Cell-derived Cardiomyocytes using Vertical-Wheel Bioreactors
PTDC/EQU-EQU/29653/2017
Bolseiro de Mestrado
Fundação para a Ciência e a Tecnologia, Portugal
Em curso
2021/03/01 - 2021/12/06 SMART: New technologies for Stem cell Manufacturing bioprocess monitoring and ARTificial intelligence-based modeling
PTDC/EQU-EQU/3853/2020
Bolseiro de Mestrado
Fundação para a Ciência e a Tecnologia, Portugal
Em curso
Produções

Publicações

Artigo em jornal
  1. Salvador, William O.S.; RIBEIRO, INÊS; Nogueira, Diogo E.S.; Ferreira, Frederico C. ; Cabral, Joaquim M.S; Rodrigues, Carlos A.V.. Autor correspondente: Rodrigues, Carlos A.V.. "Bioprocess Economic Modeling: Decision Support Tools for the Development of Stem Cell Therapy Products", Bioengineering, 2022, https://www.mdpi.com/2306-5354/9/12/791.
Tese / Dissertação
  1. "Cardiac Differentiation of Human Induced Pluripotent Stem Cells in Vertical-Wheel Reactors". Mestrado, 2021.