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Susana Costa completed her BSc degree in Biochemistry in 2017 and her MSc degree in Cellular and Molecular Biology in 2019, at the University of Coimbra. She published 3 papers in peer-reviewed journals. Her MSc thesis was developed at the "RNA & Infection" laboratory, under the supervision of Dr Ana Eulalio, at the Center for Neurosciences and Cell Biology (CNC-CIBB, University of Coimbra). This work allowed her to specialize in the study of host-pathogen interactions, the intracellular lifestyle of Salmonella Typhimurium and microRNAs. She has worked as a Research Fellow at the "RNA & Infection" and "Functional Genomics and RNA-Based Therapeutics" headed by Dr. Ana Eulalio and Dr. Miguel Mano, respectively. She is currently a PhD student in the PhD Programme in Experimental Biology and Biomedicine (PDBEB). Her PhD work is focused on identifying and characterizing host factors that regulate the intracellular lifestyle of various bacterial pathogens, including Salmonella.
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Identificação

Identificação pessoal

Nome completo
Susana Maria dos Santos Costa
Data de nascimento
1996/06/11
Género
Feminino

Nomes de citação

  • Costa, Susana

Identificadores de autor

Ciência ID
371A-9C60-E497
ORCID iD
0000-0002-3020-5918

Endereços de correio eletrónico

  • susana.mscosta96@gmail.com (Profissional)

Telefones

Telefone
  • 231419040 (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Microbiologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português (Idioma materno)
Formação
Grau Classificação
2020 - 2025
Em curso
 Experimental Biology and Biomedicine (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019
Concluído
 Cellular and Molecular Biology (Mestrado)
Especialização em Área de especialização: Biologia Molecular e Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Towards a better understanding of host cell requirements for Salmonella cytosolic replication" (TESE/DISSERTAÇÃO)
 19/20
2017
Concluído
 Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Notch signalling in adipose tissue after bariatric surgery in diabetic rats: implications for angiogenesis" (TESE/DISSERTAÇÃO)
 17/20
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/12/01 - Atual PhD Student, RNA & Infection Laboratory Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2019/11/15 - 2020/11/30 Research Fellow (MSc), RNA & Infection Laboratory/Functional Genomics and RNA-based Therapeutics Laboratory Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/06/01 - 2019/09/04 MSc Thesis Project, RNA & Infection Laboratory Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/04/02 - 2018/04/30 Laboratory Rotation, RNA & Infection Laboratory Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
2018/01/29 - 2018/02/23 Laboratory Rotation, Laboratory of Physiology Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/02/05 - 2017/07/15 BSc Final Project, Laboratory of Physiology Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/07/18 - 2016/09/16 Research Trainee, Laboratory of Microbiology Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2020/12/01 - Atual Deciphering host cell microRNAs controlling Salmonella replication and persistence within macrophages
2020.06572.BD
Bolseiro de Doutoramento
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/02/01 - 2020/11/30 Intracellular Staphylococcus aureus: deciphering bacterial and cellular factors involved in host cell invasion by clinically relevant strains to define new therapeutic approaches (StaphIN)
Infect-ERA/0001/2015
Bolseiro de Investigação
Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 European Commission Seventh Framework Programme for Research and Technological Development Health
Produções

Publicações

Artigo em revista
  1. Lisowski, Clivia; Dias, Jane; Costa, Susana; Silva, Ricardo Jorge; Mano, Miguel; Eulalio, Ana. "Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication". Autophagy (2021): 1-16. http://dx.doi.org/10.1080/15548627.2021.1999561.
    10.1080/15548627.2021.1999561
  2. Aguilar, Carmen; Costa, Susana; Maudet, Claire; Vivek-Ananth, R. P.; Zaldívar-López, Sara; Garrido, Juan J.; Samal, Areejit; Mano, Miguel; Eulalio, Ana. "Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells". Nature Communications 12 1 (2021): http://dx.doi.org/10.1038/s41467-021-23593-z.
    10.1038/s41467-021-23593-z
  3. Eickhoff, Hans; Rodrigues, Tiago; Neves, Inês; Marques, Daniela; Ribeiro, Diana; Costa, Susana; Seiça, Raquel; Matafome, Paulo. "Effect of Sleeve Gastrectomy on Angiogenesis and Adipose Tissue Health in an Obese Animal Model of Type 2 Diabetes". Obesity Surgery 29 9 (2019): 2942-2951.
    10.1007/s11695-019-03935-z
Poster em conferência
  1. Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. Autor correspondente: Costa, Susana. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Trabalho apresentado em Antimicrobial Chemotherapy Conference 2025, 2025.
  2. Costa, Susana; Caio Franco; Miguel Mano; Ana Euláio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Trabalho apresentado em Non-coding RNA World 2024: Exploring Mechanisms, Designing Medicines, 2024.
  3. Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Trabalho apresentado em EMBO | EMBL Symposium: The non-coding genome, 2023.
  4. Costa, Susana; Caio Franco; Miguel Mano; Ana Eulálio. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Trabalho apresentado em BEB DAY 2023 - Science Challenges: This fight of ours, 2023.
  5. Franco, C. H.; Costa, Susana; Mano, Miguel; Eulalio, Ana. "Identification of host microRNAs regulating the infection of macrophages by invasive and non-invasive Salmonella strains". Trabalho apresentado em XI ptRNA Meeting - RNA in Disease, 2023.
Tese / Dissertação
  1. Costa, Susana Maria dos Santos. "Towards a better understanding of host cell requirements for Salmonella cytosolic replication". Mestrado, 2019. http://hdl.handle.net/10316/88111.
Atividades

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2024/12 - Atual “Superbugs: The invisible threat” - Development and execution of multiple activities including ludic games to perform with elementary school students. The activities were focused on microbiology, bacterial pathogens and the threat of antibiotic resistance to public health. Semana da Ciência & Tecnologia CiBB
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2024/09 - 2024/09 European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments. European Research Night
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2023/09 - 2023/09 European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments.
Exposição
 European Research Night
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/09 - 2022/09 European Research Night - Communicate Science to Society Awareness about multi-resistant bacteria and the efforts of scientists to find new strategies to combat infections Development of didactic activities for different group ages, including a card game and environmental microbiology experiments.
Exposição
 European Research Night
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/01/18 - 2022/01/19 PDBEB Students meeting
Simpósio
 BEB Day 2022 - The Overview Effect
Universidade de Coimbra, Portugal
2021/03/15 - 2021/03/19 Lecturers address multiple aspects of infection, host responses to strategies to fight infectious agents and highlight the importance of constantly monitoring environmental microbiology and epidemiology.
Oficina (workshop)
 Fighting Infection Course
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/02/01 - 2021/02/05 The course was focused on the principles, design, and application of different types of screenings (interference RNA; drug; CRISPR...), applied to diverse models (in vitro and in vivo) and diverse research fields. Practical sessions of microscopy image analysis using Columbus and Cellprofiler software.
Oficina (workshop)
 High-Throughput Screening for Target and Drug Discovery Course
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/11/11 - 2019/11/11 Meeting with theoretical sessions for the basis of Scanning Electron Microscopy, complemented with practical sessions: preparation of biological samples for scanning electron microscopy; negative staining (IGC).
Oficina (workshop)
 IV Technical Meeting of Electron Microscopy
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/09/10 - 2018/09/10 Online course: Introduction to BSL-2. By labsafetyworkspace.org
Outro
2018/09/09 - 2018/09/09 Online course : Introduction to Laboratory Safety. By labsafetyworkspace.org
Outro
2016/05/28 - 2016/05/28 Pedagogic meeting of Chemistry Students. Participation in the workshops: "Nanomaterials"; "The use of proteomics to answer biological questions".
Encontro
 INPEQ - Intercâmbio Pedagógico de Estudantes de Química
Universidade de Aveiro, Portugal

Membro de associação

Nome da associação Tipo de participação
2015 - 2018 MiniBioqs - Volunteer project that promotes the realization of basic biochemistry experiences for children to encourage the practice of science in the Pediatric Hospital of Coimbra and other Institutions. Coordinator / Colaborator
Distinções

Prémio

2020 PhD Scholarship
Fundação para a Ciência e a Tecnologia, Portugal
2019 Merit Scholarship
Universidade de Coimbra, Portugal
2014 Academic excellency
Escola Secundária da Mealhada, Portugal