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Identificação

Identificação pessoal

Nome completo
Omer Markovitch

Nomes de citação

  • Markovitch, Omer

Identificadores de autor

Ciência ID
3F1A-E5CC-0F53
ORCID iD
0000-0002-9706-5323
Google Scholar ID
7HATWpEAAAAJ

Endereços de correio eletrónico

  • omermar@gmail.com (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Física - Física Química
  • Ciências Exatas - Química
  • Ciências Naturais - Ciências Biológicas - Biologia da Evolução das Espécies
  • Ciências Exatas - Química - Química Orgânica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2014
Concluído
 - (Doktor (PhD))
Weizmann Institute of Science, Israel
"Systems-Chemistry Approach to Prebiotic Evolution" (TESE/DISSERTAÇÃO)
2008
Concluído
 Chemistry (Master)
Hebrew University of Jerusalem, Israel
"Protonated Water" (TESE/DISSERTAÇÃO)
2005
Concluído
 Chemistry (Bachelor)
Hebrew University of Jerusalem, Israel
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2025 - Atual Investigador Auxiliar (carreira) (Investigação) Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2017 - Atual Investigador principal (carreira) (Investigação) Blue Marble Space Institute of Science, Estados Unidos
2021 - 2022 Investigador visitante (Investigação) Rijksuniversiteit Groningen Faculteit voor Wiskunde en Natuurwetenschappen, Países Baixos
Groningen Institute for Evolutionary Life Sciences, Países Baixos
(...)
2017 - 2021 Pós-doutorado (Investigação) Rijksuniversiteit Groningen Faculteit voor Wiskunde en Natuurwetenschappen, Países Baixos
Rijksuniversiteit Groningen Stratingh Institute for Chemistry, Países Baixos
(...)
2016 - 2017 Investigador visitante (Investigação) Tokyo Institute of Technology , Japão
Earth-Life Science Institute , Japão
2014 - 2016 Pós-doutorado (Investigação) University of Newcastle upon Tyne, Reino Unido
University of Newcastle upon Tyne, Reino Unido
Produções

Publicações

Artigo em conferência
  1. Markovitch, Omer; Weizmann Institute of Science; Lancet Doron. "Prebiotic Evolution of Molecular Assemblies: From Molecules to Ecology". 2013.
    Publicado • 10.7551/978-0-262-31709-2-ch020
Artigo em revista
  1. Eleveld, Marcel J.; Wu, Juntian; Liu, Kai; Ottelé, Jim; Markovitch, Omer; Kiani, Armin; Herold, Lukas C.; et al. "Departure from randomness: Evolution of self-replicators that can self-sort through steric zipper formation". Chem (2024): 102374. https://doi.org/10.1016/j.chempr.2024.11.012.
    10.1016/j.chempr.2024.11.012
  2. Markovitch, Omer; Wu, Juntian; Otto, Sijbren. Autor correspondente: Markovitch, Omer. "Binding of Precursors to Replicator Assemblies Can Improve Replication Fidelity and Mediate Error Correction [Hot Paper]". Angewandte Chemie International Edition (2024): e202317997. http://dx.doi.org/10.1002/anie.202317997.
    Acesso aberto • 10.1002/anie.202317997
  3. Mayer, Christian; Lancet, Doron; Markovitch, Omer. "The GARD Prebiotic Reproduction Model Described in Order and Complexity". Life 14 3 (2024): 288. https://doi.org/10.3390/life14030288.
    10.3390/life14030288
  4. Bin Liu; Juntian Wu; Marc Geerts; Markovitch, Omer; Charalampos G. Pappas; Kai Liu; Sijbren Otto. "Out-of-Equilibrium Self-Replication Allows Selection for Dynamic Kinetic Stability in a System of Competing Replicators". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202117605.
    Acesso aberto • Publicado • 10.1002/anie.202117605
  5. Shuo Yang; Gael Schaeffer; Elio Mattia; Markovitch, Omer; Kai Liu; Andreas S. Hussain; Jim Ottelé; Ankush Sood; Sijbren Otto. "Chemical Fueling Enables Molecular Complexification of Self-Replicators**". Angewandte Chemie International Edition 60 20 (2021): 11344-11349. http://dx.doi.org/10.1002/anie.202016196.
    Publicado • 10.26434/chemrxiv.12162135
  6. Markovitch, Omer; Jim Ottelé; Obe Veldman; Sijbren Otto. Autor correspondente: Markovitch, Omer. "Automated device for continuous stirring while sampling in liquid chromatography systems". Communications Chemistry 3 (2020): 180. https://doi.org/10.1038/s42004-020-00427-5.
    Acesso aberto • Publicado • 10.1038/s42004-020-00427-5
  7. Gregory B. Boursalian; Eise R. Nijboer; Ruth Dorel; Lukas Pfeifer; Markovitch, Omer; Alex Blokhuis; Ben L. Feringa. Autor correspondente: Ben L. Feringa. "All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement". Journal of the American Chemical Society 142 39 (2020): 16868-16876. https://doi.org/10.1021/jacs.0c08249.
    Acesso aberto • Publicado • 10.1021/jacs.0c08249
  8. Rafael Loureiro; Markovitch, Omer; Crystal S Riley; H James Cleaves, II; I Haritina Mogo¿anu; Ivan G Paulino-Lima; Jeffrey J Marlow; Sanjoy M Som. Autor correspondente: Markovitch, Omer. "Perspective: Science policy through public engagement". Science and Public Policy (2020): https://doi.org/10.1093/scipol/scaa039.
    Acesso aberto • Publicado • 10.1093/scipol/scaa039
  9. Sourav Maity; Jim Ottelé; Guillermo Monreal Santiago; Pim W. J. M. Frederix; Peter Kroon; Markovitch, Omer; Marc C. A. Stuart; et al. "Caught in the Act: Mechanistic Insight into Supramolecular Polymerization-Driven Self-Replication from Real-Time Visualization". Journal of the American Chemical Society 142 32 (2020): 13709-13717. https://doi.org/10.1021/jacs.0c02635.
    Acesso aberto • Publicado • 10.1021/jacs.0c02635
  10. Markovitch, Omer; Boris H. Kramer; Franz J. Weissing; G. Sander van Doorn; Sijbren Otto. Autor correspondente: Markovitch, Omer. "Competition Dynamics in a Chemical System of Self-replicating Macrocycles". Artificial Life (2020): http://dx.doi.org/10.1162/isal_a_00289.
    Acesso aberto • Publicado • 10.1162/isal_a_00289
  11. Doron Lancet; Raphael Zidovetzki; Markovitch, Omer. "Systems protobiology: origin of life in lipid catalytic networks". Journal of The Royal Society Interface 15 144 (2018): 20180159-20180159. https://doi.org/10.1098/rsif.2018.0159.
    Acesso aberto • Publicado • 10.1098/rsif.2018.0159
  12. Markovitch, Omer; Natalio Krasnogor. "Predicting species emergence in simulated complex pre-biotic networks". PLOS ONE 13 2 (2018): e0192871-e0192871. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192871.
    Acesso aberto • Publicado • 10.1371/journal.pone.0192871
  13. Fellermann, H.; Markovitch, Omer; Gilfellon, O.; Madsen, C.; Phillips, A.. "Toward Programmable Biology". ACS Synthetic Biology 5 8 (2016): 793-794. https://pubs.acs.org/doi/10.1021/acssynbio.6b00213.
    Acesso aberto • Publicado • 10.1021/acssynbio.6b00213
  14. Markovitch, Omer; Doron Lancet. "Multispecies population dynamics of prebiotic compositional assemblies". Journal of Theoretical Biology 357 (2014): 26-34. https://www.sciencedirect.com/science/article/abs/pii/S0022519314002756.
    Acesso aberto • Publicado • 10.1016/j.jtbi.2014.05.005
  15. Renan Gross; Itzhak Fouxon; Doron Lancet; Markovitch, Omer. Autor correspondente: Markovitch, Omer. "Quasispecies in population of compositional assemblies". BMC Evolutionary Biology 14 1 (2014): 265-265. http://dx.doi.org/10.1186/s12862-014-0265-1.
    Acesso aberto • Publicado • 10.1186/s12862-014-0265-1
  16. Markovitch, Omer; Daniel Sorek; Leong Ting Lui; Doron Lancet; Natalio Krasnogor. Autor correspondente: Markovitch, Omer. "Is There an Optimal Level of Open-Endedness in Prebiotic Evolution?". Origins of Life and Evolution of Biospheres 42 5 (2012): 469-474. http://dx.doi.org/10.1007/s11084-012-9309-y.
    Publicado • 10.1007/s11084-012-9309-y
  17. Markovitch, Omer; Lancet, D.. "Excess mutual catalysis is required for effective evolvability". Artificial Life 18 3 (2012): 243-266. https://direct.mit.edu/artl/article/18/3/243/2728/Excess-Mutual-Catalysis-Is-Required-for-Effective.
    Acesso aberto • Publicado • 10.1162/artl-a-00064
  18. Don L Armstrong; Markovitch, Omer; Raphael Zidovetzki; Doron Lancet. "Replication of simulated prebiotic amphiphile vesicles controlled by experimental lipid physicochemical properties". Physical Biology 8 6 (2011): 066001-066001. http://dx.doi.org/10.1088/1478-3975/8/6/066001.
    Publicado • 10.1088/1478-3975/8/6/066001
  19. Ran Kafri; Markovitch, Omer; Doron Lancet. "Spontaneous chiral symmetry breaking in early molecular networks". Biology Direct 5 1 (2010): http://dx.doi.org/10.1186/1745-6150-5-38.
    Acesso aberto • Publicado • 10.1186/1745-6150-5-38
  20. Markovitch, Omer; Inger, A.; Shenhav, B.; Lancet, D.. "Replication and darwinian selection define life's origin". Origins of Life and Evolution of Biospheres 40 4 (2010): 484-488. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954911470&partnerID=MN8TOARS.
  21. Markovitch, Omer; Noam Agmon. "Reversible geminate recombination of hydrogen-bonded water molecule pair". The Journal of Chemical Physics 129 8 (2008): 084505-084505. http://dx.doi.org/10.1063/1.2968608.
    Publicado • 10.1063/1.2968608
  22. Markovitch, Omer; Hanning Chen; Sergei Izvekov; Francesco Paesani; Gregory A. Voth; Noam Agmon. "Special Pair Dance and Partner Selection: Elementary Steps in Proton Transport in Liquid Water". The Journal of Physical Chemistry B 112 31 (2008): 9456-9466. http://dx.doi.org/10.1021/jp804018y.
    Publicado • 10.1021/jp804018y
  23. Markovitch, Omer; Noam Agmon. "The distribution of acceptor and donor hydrogen-bonds in bulk liquid water". Molecular Physics 106 2-4 (2008): 485-495. http://dx.doi.org/10.1080/00268970701877921.
    Publicado • 10.1080/00268970701877921
  24. Markovitch, Omer; Noam Agmon. "Structure and Energetics of the Hydronium Hydration Shells". The Journal of Physical Chemistry A 111 12 (2007): 2253-2256. http://dx.doi.org/10.1021/jp068960g.
    Publicado • 10.1021/jp068960g
Artigo em revista (magazine)
  1. Markovitch, Omer. Autor correspondente: Markovitch, Omer. "How everything began", Galileo, 2012, https://microbiology-heb.blogspot.com/2012/12/How-Life-Start.html.
Capítulo de livro
  1. Eloi Camprubi; Markovitch, Omer; Kamila B. Muchowska; Sijbren Otto; Inge Loes ten Kate. "Prebiotic chemistry: From dust to molecules and beyond". 19-47. Elsevier, 2022.
    Publicado • 10.1016/b978-0-12-824162-2.00005-1
Pré-impressão
  1. Liu, Kai; Markovitch, Omer; van Ewijk, Chris; Knelissen, Yari Katar; Kiani, Armin; Eleveld, Marcel; Roos, Wouter H.; Otto, Sijbren. "Selection for Photocatalytic Function through Darwinian Evolution of Synthetic Self-Replicators". 2024. https://doi.org/10.26434/chemrxiv-2024-x4fdr-v2.
    10.26434/chemrxiv-2024-x4fdr-v2
  2. OOLEN writing team. "What it takes to solve the Origin(s) of Life: An integrated review of techniques". 2023. https://arxiv.org/abs/2308.11665.
  3. Markovitch, Omer; Olaf Witkowski; Nathaniel Virgo. Autor correspondente: Markovitch, Omer. "Chemical Heredity as Group Selection at the Molecular Level". 2018. https://arxiv.org/abs/1802.08024.
    https://doi.org/10.48550/arXiv.1802.08024
Resumo em conferência
  1. Doron Lancet; Raphael Zidovetzki; Shenhav Barak; Markovitch, Omer. "Metabolic GARD: Replicating Catalytic Network of Lipid-Anchored Metabolites". Trabalho apresentado em XVIIIth Intl Conf on Origin of Life 2017, 2017.
    Publicado
Tese / Dissertação
  1. "Systems-chemistry approach to prebiotic evolution". Doutoramento, 2014. https://doi.org/10.5281/zenodo.1134791.
    https://doi.org/10.5281/zenodo.1134791
  2. "Protonated Water". Mestrado, Hebrew University of Jerusalem, 2007. https://huji.primo.exlibrisgroup.com/discovery/fulldisplay?vid=972HUJI_INST:972HUJI_V1&tab=LibraryCatalog&docid=alma990014428490203701&context=L&search_scope=MyInstitution&lang=en.

Outros

Conjunto de dados
  1. Omer Markovitch; Olaf Witkowski; Nathaniel Virgo. Accompnaying Dataset For: Chemical Heredity As Group Selection At The Molecular Level.
    10.5281/ZENODO.1172466
  2. Omer Markovitch; Natalio Krasnogor. Accompanying Dataset For: Predicting Species Emergence In Simulated Complex Pre-Biotic Networks.
    10.5281/ZENODO.56534
  3. Omer Markovitch; Jim Ottelé; Sijbren Otto. Accompanying files: Automated device for continuous stirring while sampling in liquid chromatography systems.
    10.5281/ZENODO.3898290
  4. Markovitch, Omer; Wu, Juntian; Otto, Sijbren. Accompanying dataset: Binding of precursors to replicator assemblies can improve replication fidelity and mediate error correction. 2023.
    10.5281/zenodo.8287184
Outra produção
  1. BCAM hosted a workshop on “Theoretical and Experimental Approaches to Goal-Directed Behavior”. 2024. Press Release. https://www.bcamath.org/en/news-events/news/bcam-hosted-workshop-theoretical-and-experimental-approaches-goal-directed.
  2. For the first time, large self-replicating molecules win evolution. 2021. Shuo Yang; Markovitch, Omer. https://sciworthy.com/for-the-first-time-self-replicating-molecules-win-evolution/.
  3. Using 3D printing to automate experiments involving stirring and liquid chromatography. 2020. Markovitch, Omer; Jim Ottelé. https://chemistrycommunity.nature.com/posts/using-3d-printing-to-automate-experiments-involving-stirring-and-liquid-chromatography.
  4. How did life get started? [YouTube]. Self-replicating systems are likely to have played a central role in the origin of life. The goal of the project is to learn principles related to the emergent behaviour we call ‘life’, from different classes of self-replicating systems including synthetic chemical replicators, RNA viruses and bacteria. This will be achieved by investigating the diversification and adaptive potential of each syste. 2019. Markovitch, Omer. https://www.youtube.com/watch?v=puJVWPWnUvg.
  5. Wikipedia ‘Hackathon’. 2017. Markovitch, Omer. https://bmsis.org/outreach-wikipedia-hackathon/.
  6. Commentary: Excess mutual catalysis is required for effective evolvability. The essays listed below (with links to pdfs) were originally published online as part of the Origin of Life Focus Group within the NASA Astrobiology Institute. 2012. Markovitch, Omer. https://www.nasa.gov/ames/spacescience-and-astrobiology/center-for-the-emergence-of-life/essays-on-the-emergence-of-life.
Software
  1. Markovitch, Omer. "Chemical model to simulate all the oxidation and exchange reactions of dithiol building blocks". 2024.
    10.5281/zenodo.12686958