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Henrique Vazão de Almeida received his Bachelor’s and Master’s degrees in Materials Engineering from Universidade NOVA (2007). Before starting his Ph.D., he worked in the Biomaterials field for 5 years (Industry-based). Henrique graduated in 2016 with his Ph.D. in Bioengineering from Trinity College Dublin, Ireland (Daniel J. Kelly and Fergal O’Brien as supervisors). In 2016, Henrique started to work as a Postdoc at Lino Ferreira’s Lab (University of Coimbra), and in 2017 he was awarded an FCT postdoctoral fellowship. In the context of the postdoctoral fellowship in cardiac tissue engineering, he moved to ITQB/iBET (2018). In 2019, he was awarded a junior PI funding (iBETXplore) to execute a project in the context of 3D bioprinted tissues for drug screening and disease modeling. In 2021, Henrique was awarded the “Individual Call to Scientific Employment Stimulus - 3rd Edition” fellowship. In the context of his recently granted award, Henrique moved to CENIMAT|i3N (2022). Henrique is a bioengineer, material engineer, and expert in nature-derived biomaterials. He is interested in novel tissue engineering and regenerative medicine approaches to restore damaged biological tissues and bioengineer in vitro models. Currently, he is focused on developing cardiac tissue engineering strategies based on conductive biomaterials. He also started to work with point-of-care devices for disease management and regenerative medicine.
Identificação

Identificação pessoal

Nome completo
Henrique Vazão de Almeida

Nomes de citação

  • Vazão de Almeida, Henrique

Identificadores de autor

Ciência ID
7C1E-12E1-6961
ORCID iD
0000-0001-9123-4475

Endereços de correio eletrónico

  • hmmv.almeida@fct.unl.pt (Profissional)

Telefones

Telefone
  • 212949626 Ext.: 11613 (Profissional)

Moradas

  • CENTRO DE INVESTIGAÇÃO EM MATERIAIS - CENIMAT|i3N, NOVA School of Science and Technology | FCT NOVA, 2829 - 516, Caparica, Almada, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais - Engenharia dos Materiais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2020/02/13 - 2020/02/14
Concluído
Grant writing course (Pós-Graduação)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/02/21 - 2018/02/22
Concluído
Hands-on course on human pluripotent stem cell culture (Postgraduate Certificate)
Especialização em human pluripotent stem cell
Institut für Molekulare Biotechnologie GmbH, Áustria
2011/10/01 - 2016/04/08
Concluído
Doctor in Philosophy, Ph.D. (Doutoramento)
Especialização em Bioengineering
University of Dublin Trinity College, Irlanda

Trinity College Dublin School of Engineering, Irlanda
"Cartilage extracellular matrix-derived scaffolds for joint regeneration" (TESE/DISSERTAÇÃO)
n/a
2015
Concluído
Postgraduate Certificate in Innovation and Entrepreneurship (Postgraduate Certificate)
University of Dublin Trinity College, Irlanda
"n/a" (TESE/DISSERTAÇÃO)
n/a
2001 - 2007
Concluído
Mestrado em Engenharia de Materiais, pós-Bolonha; Mestrado integrado, com estágio em empresa. (Mestrado)
Especialização em Biomaterials
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Synthesis and characterization of new biocompatible chitosan derivatives" (TESE/DISSERTAÇÃO)
15 ( thesis 19 valores)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2022/07/01 - Atual Investigador Contratado (Investigação) Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2021/05/01 - 2022/07/01 Investigador Contratado (Investigação) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
(...)
2018/02/01 - 2021/04/30 Pós-doutorado (Investigação) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
2017/05/01 - 2018/02/01 Pós-doutorado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/04/01 - 2017/05/01 Pós-doutorado (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2012/09/01 - 2016/07/12 Ambassador - Innovation Academy University of Dublin Trinity College, Irlanda
University of Dublin Trinity College, Irlanda
2011/09/01 - 2016/02/01 Postgraduate Researcher University of Dublin Trinity College, Irlanda
University of Dublin Trinity College, Irlanda
2011/09/01 - 2015/09/01 Teaching assistant in Biomaterials University of Dublin Trinity College, Irlanda
University of Dublin Trinity College, Irlanda
2007/09/01 - 2011/08/01 R&D Engineer and Production Manager Ceramed & Altakitin in collaboration with New University of Lisbon , Portugal
Projetos

Bolsa

Designação Financiadores
2023/05/01 - Atual PRR: Pacto Bioeconomia Azul
C644915664-00000026
Investigador
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
European Commission
Em curso
2023/01/01 - Atual PRR: From Fossil to Forest
-
Investigador
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Em curso
2023/05/01 - 2025/06/30 Emerging Printed Electronics Research Infrastructure (EMERGE)
Investigador responsável
UNINOVA Instituto de Desenvolvimento de Novas Tecnologias, Portugal
European Commission
Em curso
2023/03/01 - 2024/09/30 LIGHEART - Enhanced Cardiomyocyte Maturation by Electrical Stimulation based on Conductive Biomaterials for Drug Development
2022.08597.PTDC
Investigador responsável
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/06/01 - 2024/01/01 BEST - BiossEnSores mulTifuncionais a integrar na prática clínica e capacitação da pessoa com diabetes
ALT20 -03-0247-FEDER-113469
Investigador
Concluído
2017/05 - 2020/05 Bioengineering of mature cardiac constructs from hiPSC-derived CM for drug screening and disease modeling
SFRH/BPD/120595/2016
Bolseiro de Pós-Doutoramento
Instituto de Biologia Experimental e Tecnológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/10 - 2015/12 Cartilage extracellular matrix-derived scaffolds for joint regeneration
Bolseiro de Doutoramento
University of Dublin Trinity College, Irlanda
Science Foundation Ireland
Concluído

Projeto

Designação Financiadores
2020 - 2023 BRAV3 - Computational biomechanics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist device to provide lasting functional support to damaged hearts
Investigador
Instituto de Biologia Experimental e Tecnológica, Portugal
Horizon 2020
Em curso
2019 - 2021 3DbioprintCTE - 3D Bioprinting for Cardiac Tissue Engineering
Investigador responsável
Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica
Concluído
2018 - 2021 PEFPlateletValue - Pulsed Electric Fields for valorization of platelets with no therapeutic value into a high biomedical potential product
PTDC/BTM-ORG/32187/2017
Investigador
Instituto de Biologia Experimental e Tecnológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018 - 2020 NETDIAMOND - NEw Targets in DIAstolic heart failure: from coMOrbidities to persoNalizeD medicine
SAICTPAC/0047/2015
Investigador
Instituto de Biologia Experimental e Tecnológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2017 CARDIOSTEM- Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Concluído
2016 - 2017 NanoTrigger - Triggerable nanomaterials to modulate cell activity
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
European Commission Seventh Framework Programme for Research and Technological Development IDEAS The European Research Council
Concluído
2016 - 2017 BioPiezo - Development of novel piezoelectric materials based on nanostructured self-assembled peptide
PTDC/CTM-CTM/31679/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011 - 2015 STEMREPAIR - Novel mesenchymal stem cell based therapies for articular cartilage repair
Bolseiro de Doutoramento
University of Dublin Trinity College, Irlanda
European Commission Seventh Framework Programme for Research and Technological Development IDEAS The European Research Council
Concluído
Produções

Publicações

Artigo em conferência
  1. "Bioinspired Manufacturing of hiPSC-based Therapy Products for application in Cardiovascular Regenerative Medicine". 2020.
Artigo em revista
  1. Pinheiro, Tomás; Caetano, Joana; Fortunato, Elvira; Sales, M. Goreti F.; Vazão de Almeida, Henrique; Martins, Rodrigo. "One-Step Laser Synthesis of Copper Nanoparticles and Laser-Induced Graphene in a Paper Substrate for Non-Enzymatic Glucose Sensing". Advanced Sensor Research 3 11 (2024): http://dx.doi.org/10.1002/adsr.202400052.
    Publicado • 10.1002/adsr.202400052
  2. Matias, Maria Leonor; Pereira, Cláudia; Vazão de Almeida, Henrique; Jana, Santanu; Panigrahi, Shrabani; Menda, Ugur Deneb; Nunes, Daniela; et al. "3D printed MXene architectures for a plethora of smart applications". Materials Today Advances 23 (2024): 100512. http://dx.doi.org/10.1016/j.mtadv.2024.100512.
    10.1016/j.mtadv.2024.100512
  3. Majka, Tomasz M.; Pimentel, Ana Cláudia; Fernandes, Susete; Vazão de Almeida, Henrique; Borges, João Paulo; Martins, Rodrigo. "Experimental consideration of the effects of calcium lignosulfonate and tannic acid on the flammability and thermal properties of polylactide composites". Thermochimica Acta 737 (2024): 179769. http://dx.doi.org/10.1016/j.tca.2024.179769.
    10.1016/j.tca.2024.179769
  4. Pinheiro, Tomás; Morais, Maria; Silvestre, Sara; Carlos, Emanuel; Coelho, João; Vazão de Almeida, Henrique; Barquinha, Pedro; Fortunato, Elvira; Martins, Rodrigo. "Direct Laser Writing: From Materials Synthesis and Conversion to Electronic Device Processing". Advanced Materials 36 26 (2024): http://dx.doi.org/10.1002/adma.202402014.
    10.1002/adma.202402014
  5. Levingstone, Tanya J.; Sheehy, Eamon J.; Moran, Conor J.; Cunniffe, Gráinne M.; Diaz Payno, Pedro J.; Brady, Robert T.; Almeida, Henrique V.; et al. "Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model". Biomaterials and Biosystems 8 (2022): 100066. http://dx.doi.org/10.1016/j.bbiosy.2022.100066.
    Publicado • 10.1016/j.bbiosy.2022.100066
  6. Sebastião, Maria J.; Almeida, Henrique V.; Serra, Margarida; Hamdani, Nazha; Saraiva, Francisca; Lourenço, André P.; Barros, António S.; et al. "Unveiling Human Proteome Signatures of Heart Failure with Preserved Ejection Fraction". Biomedicines 10 11 (2022): 2943. http://dx.doi.org/10.3390/biomedicines10112943.
    Publicado • 10.3390/biomedicines10112943
  7. Salvador, Daniela; Almeida, Henrique; Rego, Duarte; Mendonça, Pedro; Sousa, Ana Paula; Serra, Margarida; Redondo, Luis. "Pulsed Electric Fields for Valorization of Platelets with No Therapeutic Value towards a High Biomedical Potential Product—A Proof of Concept". Applied Sciences 12 12 (2022): 5773. http://dx.doi.org/10.3390/app12125773.
    Publicado • 10.3390/app12125773
  8. Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida. "Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-00226-5.
    Publicado • 10.1038/s41598-021-00226-5
  9. Levingstone, Tanya J.; Moran, Conor; Almeida, Henrique V.; Kelly, Daniel J.; O'Brien, Fergal J.. "Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair". Materials Today Bio 12 (2021): 100173. http://dx.doi.org/10.1016/j.mtbio.2021.100173.
    Publicado • 10.1016/j.mtbio.2021.100173
  10. Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al. "Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation". ACS Applied Bio Materials 4 2 (2021): 1888-1899. http://dx.doi.org/10.1021/acsabm.0c01490.
    Publicado • 10.1021/acsabm.0c01490
  11. Abecasis, Bernardo; Canhão, Pedro G.M.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Gomes-Alves, Patrícia; Serra, Margarida; Alves, Paula M.. "Toward a Microencapsulated 3D hiPSC-Derived in vitro Cardiac Microtissue for Recapitulation of Human Heart Microenvironment Features". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.580744.
    Publicado • 10.3389/fbioe.2020.580744
  12. Cunniffe, G.M.; Díaz-Payno, P.J.; Sheehy, E.J.; Critchley, S.E.; Almeida, H.V.; Pitacco, P.; Carroll, S.F.; et al. "Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues". Biomaterials 188 (2019): 63-73. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056176967&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2018.09.044
  13. Almeida, Henrique V.; Dikina, Anna D.; Mulhall, Kevin J.; O’Brien, Fergal J.; Alsberg, Eben; Kelly, Daniel J.. "Porous Scaffolds Derived from Devitalized Tissue Engineered Cartilaginous Matrix Support Chondrogenesis of Adult Stem Cells". ACS Biomaterials Science & Engineering 3 6 (2017): 1075-1082. http://dx.doi.org/10.1021/acsbiomaterials.7b00019.
    Publicado • 10.1021/acsbiomaterials.7b00019
  14. Dikina, Anna D.; Almeida, Henrique V.; Cao, Meng; Kelly, Daniel J.; Alsberg, Eben. "Scaffolds Derived from ECM Produced by Chondrogenically Induced Human MSC Condensates Support Human MSC Chondrogenesis". ACS Biomaterials Science & Engineering 3 7 (2017): 1426-1436. http://dx.doi.org/10.1021/acsbiomaterials.6b00654.
    Publicado • 10.1021/acsbiomaterials.6b00654
  15. Almeida, Henrique V.; Sathy, Binulal N.; Dudurych, Ivan; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.; Almeida, H.V.; et al. "Anisotropic Shape-Memory Alginate Scaffolds Functionalized with Either Type I or Type II Collagen for Cartilage Tissue Engineering". Tissue Engineering Part a 23 1-2 (2017): 55-68. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000391740200006&KeyUID=WOS:000391740200006.
    10.1089/ten.tea.2016.0055
  16. Ronaldo J. F. C. do Amaral; Henrique V. Almeida; Daniel J. Kelly; Fergal J. O’Brien; Cathal J. Kearney. "Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy". Stem Cells International 2017 (2017): 1-10. https://doi.org/10.1155%2F2017%2F6843727.
    10.1155/2017/6843727
  17. Gouveia, P.J.; Rosa, S.; Ricotti, L.; Abecasis, B.; Almeida, H.V.; Monteiro, L.; Nunes, J.; et al. "Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes". Biomaterials 139 (2017): 213-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020728965&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2017.05.048
  18. Henrique V. Almeida; Kevin J. Mulhall; Fergal J. O'Brien; Daniel J. Kelly. "Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds". Journal of Tissue Engineering and Regenerative Medicine 11 11 (2016): 2979-2987. https://doi.org/10.1002%2Fterm.2199.
    10.1002/term.2199
  19. Almeida, H. V.; Eswaramoorthy, R.; Cunniffe, G. M.; Buckley, C. T.; O'Brien, F. J.; Kelly, Dj.. "Fibrin hydrogels functionalized with cartilage extracellular matrix and incorporating freshly isolated stromal cells as an injectable for cartilage regeneration". Acta Biomaterialia 36 (2016): 55-62. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375888000004&KeyUID=WOS:000375888000004.
    10.1016/j.actbio.2016.03.008
  20. Almeida, Henrique V.; Cunniffe, Grainne M.; Vinardell, Tatiana; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.. "Coupling Freshly Isolated CD44(+) Infrapatellar Fat Pad-Derived Stromal Cells with a TGF-3 Eluting Cartilage ECM-Derived Scaffold as a Single-Stage Strategy for Promoting Chondrogenesis". Advanced Healthcare Materials 4 7 (2015): 1043-1053. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000354481100011&KeyUID=WOS:000354481100011.
    10.1002/adhm.201400687
  21. Almeida, Henrique V.; Liu, Yurong; Cunniffe, Grainne M.; Mulhall, Kevin J.; Matsiko, Amos; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.. "Controlled release of transforming growth factor-beta 3 from cartilage-extra-cellular-matrix-derived scaffolds to promote chondrogenesis of human-joint-tissue-derived stem cells". Acta Biomaterialia 10 10 (2014): 4400-4409. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342523800034&KeyUID=WOS:000342523800034.
    10.1016/j.actbio.2014.05.030
  22. Liu, Yurong; Buckley, Conor Timothy; Almeida, Henrique V.; Mulhall, Kevin J.; Kelly, Daniel John. "Infrapatellar Fat Pad-Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and Can be Used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions". Tissue Engineering Part a 20 21-22 (2014): 3050-3062. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344592600023&KeyUID=WOS:000344592600023.
    10.1089/ten.tea.2014.0035
Livro
  1. Daniela Nunes; Ana Pimentel; Barquinha, Pedro; Manuel J. Mendes; Joao Coelho; Vazão de Almeida, Henrique; Fortunato, Elvira; Martins, Rodrigo. Flexible Devices Based on Metal Oxides: achievements and prospects. Elsevier. 2024.
    Em revisão
Poster em conferência
  1. Vazão de Almeida, Henrique. Autor correspondente: Vazão de Almeida, Henrique. "From 2D to 3D: Enhancing Cardiomyocyte Maturation in 3D Conductive Environment for Cardiovascular Tissue Engineering". Trabalho apresentado em Advances in 3D Bioprinting (Haifa, Israel), 2023.
  2. Vazão de Almeida, Henrique. Autor correspondente: Vazão de Almeida, Henrique. "Laser-Induced Graphene Anisotropic Substrates for Cardiac Tissue Engineering". Trabalho apresentado em TERMIS-EU 2023, 2023.
  3. Vazão de Almeida, Henrique. Autor correspondente: Vazão de Almeida, Henrique. "Extracellular-Matrix Functionalization of Human iPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation". Trabalho apresentado em World Biomaterial Congress, 2020.
  4. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Human Extracellular-Matrix Functionalization of Alginate-based Cardiac Tissues Derived from Pluripotent Stem Cells". Trabalho apresentado em Termis-EU 2020, 2020.
  5. Louro, Ana Filipa; Almeida, Henrique; Alves, Patrícia; Alves, Paula; Serra, Margarida. "Beyond stem cells: extracellular vesicles from hiPSC and hiPSC-cardiomyocytes as therapeutic approaches for heart failure". Trabalho apresentado em International Society of Extracellular Vesicles (ISEV) 2020, 2020.
  6. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Abecasis, Bernardo; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Extracellular Matrix Functionalization of Human Cardiac Models". Trabalho apresentado em 11th International Meeting of the Portuguese Society For Stem Cells and Cell Therapies, 2019.
  7. Louro, Ana Filipa; Kasper, Katarina; Paiva, Marta; Almeida, Henrique; Alves, Patrícia; Alves, Paula; Serra, Margarida. "Beyond Stem Cells: EVs from hiPSC-Cardiomyocytes as Therapeutic Approaches to Heart Failure". Trabalho apresentado em EMBO practical course - "Extracellular Vesicles: from Biology to Biomedical Applications", 2019.
  8. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Engineering 3D hiPSC-based Cardiac Tissues for Preclinical Research". Trabalho apresentado em Advances in Cell Based Screening in Drug Discovery, 2019.
  9. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Gouveia, Pedro; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "3D hiPSC-based Cardiac Tissues For Preclinical Research". Trabalho apresentado em 26th ESACT Meeting, 2019.
  10. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Gouveia, Pedro; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Towards a microencapsulated 3D hiPSC-derived in vitro cardiac microtissue for recapitulation of human heart microenvironment features". Trabalho apresentado em ESTIV 2018, 2018.
  11. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Alves, Patricia; Rosa, Susana; Gouveia, Pedro; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Development of a complex engineered cardiac tissue using human induced pluripotent stem cell derivatives". Trabalho apresentado em Cardiovascular Research Workshop @ Bayer, 2018.
  12. Critchley, Susan; O'Reilly, Adam; Cunniffe, Grainne; Díaz-Payno, P.J.; McAlinden, A; Almeida, Henrique; Kelly, Daniel. "Regeneration of osteochondral defects by spatial modulation of endochondral ossification within engineered cartilage grafts". Trabalho apresentado em Termis-EU 2016, 2016.
  13. Almeida, Henrique; Eswaramoorthy, Raja; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "Functionalizing fibrin hydrogels with cartilage ECM microparticles enhances chondrogenesis of human infrapatellar fat pad stem cells in vitro and in vivo". Trabalho apresentado em Orthopaedic Research Society, 2015.
  14. Almeida, Henrique; Irvine, Alan; Vinardell, Tatiana; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "An in vitro and in vivo assessment of a growth factor releasing cartilage ECM-derived scaffold seeded with infrapatellar fat pad stem cells for articular cartilage repair". Trabalho apresentado em Orthopaedic Research Society, 2014.
  15. Almeida, Henrique; Liu, Yurong; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "The composition and architecture of cartilage ECM-derived scaffolds regulates stem cell infiltration and their chondrogenic differentiation". Trabalho apresentado em Termis-EU 2013, 2013.
  16. Almeida, Henrique; Liu, Yurong; Cunniffe, Grainne; Buckley, Conor; Mulhall, Kevin; Matsiko, Amos; O'Brien, Fergal; Kelly, Daniel. "Controlled release of TGF-ß3 from cartilage extra cellular matrix-derived scaffolds induces robust chondrogenesis of diseased human stem cells". Trabalho apresentado em Orthopaedic Research Society, 2013.
  17. Cunniffe, Grainne; Almeida, Henrique; Kelly, Daniel. "Comparison of extracellular matrix-based scaffolds for cartilage tissue regeneration". Trabalho apresentado em 3rd TERMIS World Congress, Vienna, Austria, 2012.
    10.5220/0002765102290234
Resumo em conferência
  1. Eswaramoorthy, R.; Almeida, Henrique; Critchley, Susan; Downey, Richard; Mulhall, Kevin J.; Kelly, Daniel. "A co-culture of chondrons and infra-patellar fat pad derived stem cells isolated from osteoarthritic joints enhances chondrogenesis in both normoxic and hypoxic environments". Trabalho apresentado em TERMIS, 2014.
    10.1002/term.1931
  2. Almeida, Henrique; Eswaramoorthy, R.; Vinardell, Tatiana; Cunniffe, Grainne; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel. "Combining human infrapatellar fat pad stem cells with a growth factor releasing ECM-derived scaffold to develop a single-stage therapy for cartilage repair: in vitro and in vivo assessment". Trabalho apresentado em TERMIS, 2014.
    Publicado
  3. Díaz-Payno, Pedro; Ramey, James Scott; Almeida, Henrique; Cunniffe, Grainne; Kelly, Daniel. "Layered decellularized extracellular matrix derived scaffolds for osteochondral tissue engineering". Trabalho apresentado em TERMIS, 2014.
    Publicado
  4. Almeida, Henrique; Buckley, Conor; Cunniffe, Grainne; Ahearne, Mark; O'Brien, Fergal; Kelly, Daniel. "Combining freshly isolated CD271+ positive infrapatellar fat pad stem cells and a TGF-b3 releasing scaffold to develop a single stage therapy for cartilage repair". Trabalho apresentado em TERMIS, Vienna, 2012.
    Publicado
  5. Cunniffe, Grainne; Almeida, Henrique; Kelly, Daniel. "Comparison of extracellular matrix-based scaffolds for cartilage tissue regeneration". Trabalho apresentado em TERMIS, Vienna, 2012.
    Publicado
Tese / Dissertação
  1. Almeida, Henrique. "Cartilage extracellular matrix-derived scaffolds for joint regeneration". Doutoramento, University of Dublin Trinity College, 2016. http://www.tara.tcd.ie/handle/2262/82890?show=full.
  2. Almeida, Henrique. "Synthesis and characterization of new biocompatible chitosan derivatives". Mestrado, Universidade Nova de Lisboa, 2007.

Propriedade Intelectual

Patente
  1. 2020. "Method for making a porous scaffold suitable for use in repair of osseous, chondral, or osteochondral defects in a mammal".
    Concedida/Emitida
Pedido provisório de patente
  1. 2017. "A method for making a porous scaffold suitable for use in repair of osseous, chondral, or osteochondral defects in a mammal".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/09 Unleashing the Potential of Laser-Induced Graphene for Cardiomyocyte Stimulation in Cardiac Tissue Engineering E-MRS
(Warsaw, Polónia)
2021/11/15 Extracellular matrix functionalization of human induced pluripotent stem cell-based cardiac tissues improves cardiomyocyte maturation 5th TERMIS World Congress
TERMIS (Maastricht, Países Baixos)
2019/05 ECM Functionalization of Stem Cell-Derived Cardiac 3D Spheroids TERMIS-EU 2019
TERMIS (Rhodes, Grécia)
2019/05 Engineering 3D hiPSC-based Cardiac Tissues for Preclinical Research TERMIS-EU 2019
TERMIS (Rhodes, Grécia)
2019/05 Extracellular-Matrix Functionalization of human iPSC-based cardiac tissues improves cardiomyocyte maturation SPCCTV 4D Visions
SPCCTV (Albufeira, Portugal)
2016/06/28 A bilayered scaffold derived from growth plate and articular cartilage extracellular matrix for osteochondral tissue regeneration in a caprine model TERMIS-EU 2016
TERMIS (Uppsala, Suécia)
2016/01 Regeneration of osteochondral defects by spatial modulation of endochondral ossification within engineered cartilage grafts Bioengineering in Ireland 22nd Annual Conference
(Galway, Irlanda)
2016/01 A bi-phasic scaffold derived from growth plate & articular cartilage ECM for osteochondral defect repair in a caprine model Bioengineering in Ireland 22nd Annual Conference
(Galway, Irlanda)
2016/01 Directed osteogenesis and chondrogenesis in a multi-layered osteochondral scaffold facilitates joint regeneration in a goat model using both cell-free and cell-seeded approaches Bioengineering in Ireland 22nd Annual Conference
(Galway, Irlanda)
2015/01 Functionalizing fibrin hydrogels with cartilage ECM microparti-cles enhances chondrogenesis of human infrapatellar fat pad stem cells in vitro and in vivo Bioengineering in Ireland 21nd Annual Conference
(Maynooth, Irlanda)
2015/01 Development of a bilayered decellularized extracellular matrix (ECM) derived scaffold for osteochondral tissue engineering Bioengineering in Ireland 21nd Annual Conference
(Maynooth, Irlanda)
2014/06/10 Combining human infrapatellar fat pad stem cells with a growth factor releasing ECM-derived scaffold to develop a single-stage therapy for cartilage repair: in vitro and in vivo assessment TERMIS-EU 2014
TERMIS (Genoa, Itália)
2014/06/10 A co-culture of chondrons and infrapatellar-derived stem cells isolated from osteoarthritic joints enhances chondrogenesis in both normoxic and hypoxic environments TERMIS-EU 2014
TERMIS (Genoa, Itália)
2014/06/10 Layered decellularized extracellular matrix-derived scaffolds for osteochondral tissue engineering TERMIS-EU 2014
TERMIS (Genoa, Itália)
2014/01 An in vitro and in vivo assessment of a growth factor releasing cartilage ECM-derived scaffold seeded with infrapatellar fat pad stem cells for articular cartilage repair Bioengineering in Ireland 20nd Annual Conference
(Limerick, Irlanda)
2014/01 The effect of oxygen tension on cartilage engineered using diseased human stem cells within ECM-derived scaffolds Bioengineering in Ireland 20nd Annual Conference
(Limerick, Irlanda)
2014/01 Layered decellularized extracellular matrix (ECM) derived scaffolds for osteo-chondral defect regeneration Bioengineering in Ireland 20nd Annual Conference
(Limerick, Irlanda)
2013/09 Optimizing cartilage extracellular matrix-derived scaffolds to act as growth factor delivery platforms to promote chondrogenesis of mesenchymal stem cells “Where Science meets Clinic” The symposium of AOER
AOER (Davos, Suiça)
2013/01 Controlled release of TGF- ß3 from cartilage extra cellular matrix derived scaffolds induces robust chondrogenesis of diseased human stem cells Bioengineering in Ireland 19nd Annual Conference
(Co. Meath, Irlanda)
2012/01 Combining freshly isolated CD271+ positive infrapatellar fat pad stem cells and a TGF-ß3 releasing scaffold to develop a single stage therapy for cartilage repair Bioengineering in Ireland 18nd Annual Conference
(Belfast, Reino Unido)
2012 Combining freshly isolated CD271+ infrapatellar fat pad stem cells and TGF-ß3 releasing scaffold to develop a single stage therapy for cartilage repair 3rd TERMIS World Congress
TERMIS (Vienna)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021/09/01 - 2025/09/01 Skin interfaced graphene-based platforms for sweat analysis
Orientador
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2022/12/01 - 2023/10/31 Estudo do impacto de diferentes materiais na deteção do CMV nos Dried blood spots; Study of the impact of different materials on CMV detection in Dried blood spots
Coorientador
Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2023/02/01 - 2023/09/30 3D-Bioprinted Conductive Substrates for Cardiac Tissue Engineering
Orientador
Engenharia Biomédica (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 Nature-derived Conductive Scaffolds for Therapeutic Applications (Chitosan)
Orientador
Ciências de Engenharia de Micro e Nanotecnologias (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 Nature-derived Conductive Scaffolds for Therapeutic Applications (Collagen)
Orientador
Engenharia Biomédica (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 ZrO2 Nanostructures on Anisotropic Alginate Scaffolds for Osteochondral Tissue Engineering
Orientador
Ciências de Engenharia de Micro e Nanotecnologias (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/01/01 - 2023/09/30 Biofabrication of Conductive and Magnetic Auxetic Materials for Cardiac Regeneration
Orientador
Enhenharia Biomédica e Biofísica (Mestrado)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2018 - 2022/07/05 Cell-based and cell-free strategies for cardiac repair (PD/BD/139078/2018)
Coorientador
MIT-Portugal (Doutoramento)
Instituto de Biologia Experimental e Tecnológica, Portugal
2018 - 2019 Engineering Extracellular Matrix-derived Constructs for Human Cardiac Tissue Models
Coorientador
Engenharia Biomédica (Mestrado)
Instituto de Biologia Experimental e Tecnológica, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2023/01/01 - 2023/03/05 VIII Annual Meeting - Jornadas i3N 2023 (https://www.i3n.org/viii-annual-meeting-jornadas-i3n-2023) (2023/03/03 - 2023/03/04)
Encontro (Membro da Comissão Organizadora)
Instituto de Nanoestruturas Nanomodelação e Nanofabricação, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2024 New Multiresponsive Materials Platforms for Cancer Treatment: Smart Electroconductive Nanoparticles and Transdermal Devices
Arguente
Leonor Resina (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universitat Politècnica de Catalunya, Espanha
2023/11 DEVELOPMENT OF NEW HYDROGEL BIOINKS FOR LIGHT-BASED BIOPRINTING 4D MATERIALS FOR ADDITIVE MANUFACTURING
Arguente principal
Vasco Teixeira (Mestrado)
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2023/09 BIOPRINTING OF ENZYMATICALLY CROSSLINKED HYALURONIC ACIDGELATIN HYDROGELS
Arguente principal
TERESA DÍAZ JORDÀ (Mestrado)
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2023/05 POLY(IONIC LIQUID) DERIVED MATERIALS FOR TISSUE ENGINEERING APPLICATIONS
Arguente principal
Marta Alexandra de Oliveira Henriques (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/10 Design and fabrication of microgel shapes as red blood cell substitutes (RBCs) by UV-assisted punching
Arguente principal
MARIANA FILIPA DE ABREU ALVES (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/09 3D BIOPRINTED CONDUCTIVE HYDROGEL FOR OPTIMIZED SMOOTH MUSCLE TISSUE ENGINEERING
Arguente principal
CLÁUDIA VAZQUEZ PEREIRA (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/07 Cryopreservation and cold storage of human induced pluripotent stem cell-derived cardiomyocytes
Arguente principal
Beatriz Assunção Gamelas (Outro)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022 The role of DAND5 in the coordination of hiPSC-derived cardiomyocyte environmental cues: their impact on cardiomyocyte electrophysiology
Arguente principal
Mafalda Dos Santos Marques Nunes (Mestrado)
2022 Desenvolvimento de um modelo de epiderme 3D inflamada, in vitro, para avaliar a eficácia de compostos anti-inflamatórios; Development of an in vitro 3D inflamed epidermis model to evaluate the efficacy of anti-inflammatory compounds
Arguente principal
Madalena Celeiro Rei (Mestrado)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022 - Atual Biosensors Universidade Nova de Lisboa, Portugal
2022 - Atual Introduction to Material Science & Engineering Universidade Nova de Lisboa, Portugal
2022 - Atual Nanofabrication & Characterization of Biomaterials Universidade Nova de Lisboa, Portugal
2022 - Atual Introduction to Micro & Nanotechnology Universidade Nova de Lisboa, Portugal
2011 - 2015 Biomaterials Mechanical Engineering (Master) University of Dublin Trinity College, Irlanda

Membro de associação

Nome da associação Tipo de participação
2012 - Atual TERMIS - Tissue Engineering and Regenerative Medicine International Society

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021/09/01 - Atual ITQB/iBET Postdoctoral Association (PDA) - The ITQB/iBET Postdoctoral Association (PDA) represents and supports interests of the early career researchers working at Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA) and at Instituto de Biologia Experimental e Tecnológica (iBET). The PDA exists to promote a sense of community among the early career researchers, to organise activities that enhance professional and personal development, to organise networking and career development events.
Coordenador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Distinções

Outra distinção

2021 Stimulus of Scientific Employment, Individual Support (CEECIND) - 3rd Edition
Fundação para a Ciência e a Tecnologia, Portugal
2019 Bioengineering of 3D-Bioprinted Constructs for Cardiac Tissue Engineering (3DBioPrintCTE) - iBETXplore starting grant, 2019.
Instituto de Biologia Experimental e Tecnológica, Portugal
2017 Postdoctoral Fellowship (SFRH/BPD/120595/2016)
Fundação para a Ciência e a Tecnologia, Portugal
2014 2nd Prize in PhD Student Category for Annual Symposium
University of Dublin Trinity College, Irlanda
2013 CRANN Commercialization Award (1)
2013 CRANN Commercialization Award (2)
2011 Graduate Research Education Program (GREP-Eng) in Engineering funding award
University of Dublin Trinity College, Irlanda

European Regional Development Fund, Bélgica
2007 Student with the highest score for Master degree in Material Science and Engineering
Universidade Nova de Lisboa, Portugal