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Henrique Vazão de Almeida received his Bachelor’s and Master’s degrees in Materials Engineering from Universidade NOVA (2007). Before starting his Ph.D., he worked in the Biomaterials field for 5 years (Industry-based). Henrique graduated in 2016 with his Ph.D. in Bioengineering from Trinity College Dublin, Ireland (Daniel J. Kelly and Fergal O’Brien as supervisors). In 2016, Henrique started to work as a Postdoc at Lino Ferreira’s Lab (University of Coimbra), and in 2017 he was awarded an FCT postdoctoral fellowship. In the context of the postdoctoral fellowship in cardiac tissue engineering, he moved to ITQB/iBET (2018). In 2019, he was awarded a junior PI funding (iBETXplore) to execute a project in the context of 3D bioprinted tissues for drug screening and disease modeling. In 2021, Henrique was awarded the “Individual Call to Scientific Employment Stimulus - 3rd Edition” fellowship. In the context of his recently granted award, Henrique moved to CENIMAT|i3N (2022). Henrique is a bioengineer, material engineer, and expert in nature-derived biomaterials. He is interested in novel tissue engineering and regenerative medicine approaches to restore damaged biological tissues and bioengineer in vitro models. Currently, he is focused on developing cardiac tissue engineering strategies based on conductive biomaterials. He also started to work with point-of-care devices for disease management and regenerative medicine.
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Identification

Personal identification

Full name
Henrique Vazão de Almeida

Citation names

  • Vazão de Almeida, Henrique

Author identifiers

Ciência ID
7C1E-12E1-6961
ORCID iD
0000-0001-9123-4475

Email addresses

  • hmmv.almeida@fct.unl.pt (Professional)

Telephones

Telephone
  • 212949626 Ext.: 11613 (Professional)

Addresses

  • CENTRO DE INVESTIGAÇÃO EM MATERIAIS - CENIMAT|i3N, NOVA School of Science and Technology | FCT NOVA, 2829 - 516, Caparica, Almada, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Materials Engineering - Materials Engineering
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2020/02/13 - 2020/02/14
Concluded
 Grant writing course (Pós-Graduação)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/02/21 - 2018/02/22
Concluded
 Hands-on course on human pluripotent stem cell culture (Postgraduate Certificate)
Major in human pluripotent stem cell
Institut für Molekulare Biotechnologie GmbH, Austria
2011/10/01 - 2016/04/08
Concluded
 Doctor in Philosophy, Ph.D. (Doutoramento)
Major in Bioengineering
University of Dublin Trinity College, Ireland

Trinity College Dublin School of Engineering, Ireland
"Cartilage extracellular matrix-derived scaffolds for joint regeneration" (THESIS/DISSERTATION)
 n/a
2015
Concluded
 Postgraduate Certificate in Innovation and Entrepreneurship (Postgraduate Certificate)
University of Dublin Trinity College, Ireland
"n/a" (THESIS/DISSERTATION)
 n/a
2001 - 2007
Concluded
 Mestrado em Engenharia de Materiais, pós-Bolonha; Mestrado integrado, com estágio em empresa. (Mestrado)
Major in Biomaterials
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Synthesis and characterization of new biocompatible chitosan derivatives" (THESIS/DISSERTATION)
 15 ( thesis 19 valores)
Affiliation

Science

Category
Host institution 		Employer
2022/07/01 - Current Contracted Researcher (Research) Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2021/05/01 - 2022/07/01 Contracted Researcher (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
(...)
2018/02/01 - 2021/04/30 Postdoc (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
2017/05/01 - 2018/02/01 Postdoc (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/04/01 - 2017/05/01 Postdoc (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra, Portugal

Others

Category
Host institution 		Employer
2012/09/01 - 2016/07/12 Ambassador - Innovation Academy University of Dublin Trinity College, Ireland
University of Dublin Trinity College, Ireland
2011/09/01 - 2016/02/01 Postgraduate Researcher University of Dublin Trinity College, Ireland
University of Dublin Trinity College, Ireland
2011/09/01 - 2015/09/01 Teaching assistant in Biomaterials University of Dublin Trinity College, Ireland
University of Dublin Trinity College, Ireland
2007/09/01 - 2011/08/01 R&D Engineer and Production Manager Ceramed & Altakitin in collaboration with New University of Lisbon , Portugal
Projects

Grant

Designation Funders
2023/05/01 - Current PRR: Pacto Bioeconomia Azul
C644915664-00000026
Researcher
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
European Commission
Ongoing
2023/01/01 - Current PRR: From Fossil to Forest
-
Researcher
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Ongoing
2023/05/01 - 2025/06/30 Emerging Printed Electronics Research Infrastructure (EMERGE)
Grant agreement ID: 101008701
Principal investigator
UNINOVA Instituto de Desenvolvimento de Novas Tecnologias, Portugal
 European Commission
Ongoing
2023/03/01 - 2024/09/30 LIGHEART - Enhanced Cardiomyocyte Maturation by Electrical Stimulation based on Conductive Biomaterials for Drug Development
2022.08597.PTDC
Principal investigator
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/06/01 - 2024/01/01 BEST - BiossEnSores mulTifuncionais a integrar na prática clínica e capacitação da pessoa com diabetes
ALT20 -03-0247-FEDER-113469
Researcher
Concluded
2017/05 - 2020/05 Bioengineering of mature cardiac constructs from hiPSC-derived CM for drug screening and disease modeling
SFRH/BPD/120595/2016
Post-doc Fellow
Instituto de Biologia Experimental e Tecnológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/10 - 2015/12 Cartilage extracellular matrix-derived scaffolds for joint regeneration
GREP Eng
PhD Student Fellow
University of Dublin Trinity College, Ireland
 Science Foundation Ireland
Concluded

Contract

Designation Funders
2020 - 2023 BRAV3 - Computational biomechanics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist device to provide lasting functional support to damaged hearts
874827
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
 Horizon 2020
Ongoing
2019 - 2021 3DbioprintCTE - 3D Bioprinting for Cardiac Tissue Engineering
3DBioprintCTE
Principal investigator
Instituto de Biologia Experimental e Tecnológica, Portugal
 Instituto de Biologia Experimental e Tecnológica
Concluded
2018 - 2021 PEFPlateletValue - Pulsed Electric Fields for valorization of platelets with no therapeutic value into a high biomedical potential product
PTDC/BTM-ORG/32187/2017
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018 - 2020 NETDIAMOND - NEw Targets in DIAstolic heart failure: from coMOrbidities to persoNalizeD medicine
SAICTPAC/0047/2015
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2017 CARDIOSTEM- Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications
info:eu-repo/grantAgreement/FCT/5665-PICT/137185/PT
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Concluded
2016 - 2017 NanoTrigger - Triggerable nanomaterials to modulate cell activity
307384
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission Seventh Framework Programme for Research and Technological Development IDEAS The European Research Council
Concluded
2016 - 2017 BioPiezo - Development of novel piezoelectric materials based on nanostructured self-assembled peptide
PTDC/CTM-CTM/31679/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011 - 2015 STEMREPAIR - Novel mesenchymal stem cell based therapies for articular cartilage repair
258463
PhD Student Fellow
University of Dublin Trinity College, Ireland
 European Commission Seventh Framework Programme for Research and Technological Development IDEAS The European Research Council
Concluded
Outputs

Publications

Conference abstract
  1. Eswaramoorthy, R.; Almeida, Henrique; Critchley, Susan; Downey, Richard; Mulhall, Kevin J.; Kelly, Daniel. "A co-culture of chondrons and infra-patellar fat pad derived stem cells isolated from osteoarthritic joints enhances chondrogenesis in both normoxic and hypoxic environments". Paper presented in TERMIS, 2014.
    10.1002/term.1931
  2. Almeida, Henrique; Eswaramoorthy, R.; Vinardell, Tatiana; Cunniffe, Grainne; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel. "Combining human infrapatellar fat pad stem cells with a growth factor releasing ECM-derived scaffold to develop a single-stage therapy for cartilage repair: in vitro and in vivo assessment". Paper presented in TERMIS, 2014.
    Published
  3. Díaz-Payno, Pedro; Ramey, James Scott; Almeida, Henrique; Cunniffe, Grainne; Kelly, Daniel. "Layered decellularized extracellular matrix derived scaffolds for osteochondral tissue engineering". Paper presented in TERMIS, 2014.
    Published
  4. Almeida, Henrique; Buckley, Conor; Cunniffe, Grainne; Ahearne, Mark; O'Brien, Fergal; Kelly, Daniel. "Combining freshly isolated CD271+ positive infrapatellar fat pad stem cells and a TGF-b3 releasing scaffold to develop a single stage therapy for cartilage repair". Paper presented in TERMIS, Vienna, 2012.
    Published
  5. Cunniffe, Grainne; Almeida, Henrique; Kelly, Daniel. "Comparison of extracellular matrix-based scaffolds for cartilage tissue regeneration". Paper presented in TERMIS, Vienna, 2012.
    Published
Conference paper
  1. "Bioinspired Manufacturing of hiPSC-based Therapy Products for application in Cardiovascular Regenerative Medicine". 2020.
Conference poster
  1. Vazão de Almeida, Henrique. Corresponding author: Vazão de Almeida, Henrique. "From 2D to 3D: Enhancing Cardiomyocyte Maturation in 3D Conductive Environment for Cardiovascular Tissue Engineering". Paper presented in Advances in 3D Bioprinting (Haifa, Israel), 2023.
  2. Vazão de Almeida, Henrique. Corresponding author: Vazão de Almeida, Henrique. "Laser-Induced Graphene Anisotropic Substrates for Cardiac Tissue Engineering". Paper presented in TERMIS-EU 2023, 2023.
  3. Vazão de Almeida, Henrique. Corresponding author: Vazão de Almeida, Henrique. "Extracellular-Matrix Functionalization of Human iPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation". Paper presented in World Biomaterial Congress, 2020.
  4. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Human Extracellular-Matrix Functionalization of Alginate-based Cardiac Tissues Derived from Pluripotent Stem Cells". Paper presented in Termis-EU 2020, 2020.
  5. Louro, Ana Filipa; Almeida, Henrique; Alves, Patrícia; Alves, Paula; Serra, Margarida. "Beyond stem cells: extracellular vesicles from hiPSC and hiPSC-cardiomyocytes as therapeutic approaches for heart failure". Paper presented in International Society of Extracellular Vesicles (ISEV) 2020, 2020.
  6. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Abecasis, Bernardo; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Extracellular Matrix Functionalization of Human Cardiac Models". Paper presented in 11th International Meeting of the Portuguese Society For Stem Cells and Cell Therapies, 2019.
  7. Louro, Ana Filipa; Kasper, Katarina; Paiva, Marta; Almeida, Henrique; Alves, Patrícia; Alves, Paula; Serra, Margarida. "Beyond Stem Cells: EVs from hiPSC-Cardiomyocytes as Therapeutic Approaches to Heart Failure". Paper presented in EMBO practical course - "Extracellular Vesicles: from Biology to Biomedical Applications", 2019.
  8. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Engineering 3D hiPSC-based Cardiac Tissues for Preclinical Research". Paper presented in Advances in Cell Based Screening in Drug Discovery, 2019.
  9. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Gouveia, Pedro; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "3D hiPSC-based Cardiac Tissues For Preclinical Research". Paper presented in 26th ESACT Meeting, 2019.
  10. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Rosa, Susana; Gouveia, Pedro; Alves, Patrícia; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Towards a microencapsulated 3D hiPSC-derived in vitro cardiac microtissue for recapitulation of human heart microenvironment features". Paper presented in ESTIV 2018, 2018.
  11. Abecasis, Bernardo; Canhão, Pedro; Almeida, Henrique; Alves, Patricia; Rosa, Susana; Gouveia, Pedro; Ferreira, Lino; Serra, Margarida; Alves, Paula. "Development of a complex engineered cardiac tissue using human induced pluripotent stem cell derivatives". Paper presented in Cardiovascular Research Workshop @ Bayer, 2018.
  12. Critchley, Susan; O'Reilly, Adam; Cunniffe, Grainne; Díaz-Payno, P.J.; McAlinden, A; Almeida, Henrique; Kelly, Daniel. "Regeneration of osteochondral defects by spatial modulation of endochondral ossification within engineered cartilage grafts". Paper presented in Termis-EU 2016, 2016.
  13. Almeida, Henrique; Eswaramoorthy, Raja; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "Functionalizing fibrin hydrogels with cartilage ECM microparticles enhances chondrogenesis of human infrapatellar fat pad stem cells in vitro and in vivo". Paper presented in Orthopaedic Research Society, 2015.
  14. Almeida, Henrique; Irvine, Alan; Vinardell, Tatiana; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "An in vitro and in vivo assessment of a growth factor releasing cartilage ECM-derived scaffold seeded with infrapatellar fat pad stem cells for articular cartilage repair". Paper presented in Orthopaedic Research Society, 2014.
  15. Almeida, Henrique; Liu, Yurong; Cunniffe, Grainne; Buckley, Conor; O'Brien, Fergal; Kelly, Daniel. "The composition and architecture of cartilage ECM-derived scaffolds regulates stem cell infiltration and their chondrogenic differentiation". Paper presented in Termis-EU 2013, 2013.
  16. Almeida, Henrique; Liu, Yurong; Cunniffe, Grainne; Buckley, Conor; Mulhall, Kevin; Matsiko, Amos; O'Brien, Fergal; Kelly, Daniel. "Controlled release of TGF-ß3 from cartilage extra cellular matrix-derived scaffolds induces robust chondrogenesis of diseased human stem cells". Paper presented in Orthopaedic Research Society, 2013.
  17. Cunniffe, Grainne; Almeida, Henrique; Kelly, Daniel. "Comparison of extracellular matrix-based scaffolds for cartilage tissue regeneration". Paper presented in 3rd TERMIS World Congress, Vienna, Austria, 2012.
    10.5220/0002765102290234
Journal article
  1. Levingstone, Tanya J.; Sheehy, Eamon J.; Moran, Conor J.; Cunniffe, Gráinne M.; Diaz Payno, Pedro J.; Brady, Robert T.; Almeida, Henrique V.; et al. "Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model". Biomaterials and Biosystems 8 (2022): 100066. http://dx.doi.org/10.1016/j.bbiosy.2022.100066.
    Published • 10.1016/j.bbiosy.2022.100066
  2. Sebastião, Maria J.; Almeida, Henrique V.; Serra, Margarida; Hamdani, Nazha; Saraiva, Francisca; Lourenço, André P.; Barros, António S.; et al. "Unveiling Human Proteome Signatures of Heart Failure with Preserved Ejection Fraction". Biomedicines 10 11 (2022): 2943. http://dx.doi.org/10.3390/biomedicines10112943.
    Published • 10.3390/biomedicines10112943
  3. Salvador, Daniela; Almeida, Henrique; Rego, Duarte; Mendonça, Pedro; Sousa, Ana Paula; Serra, Margarida; Redondo, Luis. "Pulsed Electric Fields for Valorization of Platelets with No Therapeutic Value towards a High Biomedical Potential Product—A Proof of Concept". Applied Sciences 12 12 (2022): 5773. http://dx.doi.org/10.3390/app12125773.
    Published • 10.3390/app12125773
  4. Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida. "Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-00226-5.
    Published • 10.1038/s41598-021-00226-5
  5. Levingstone, Tanya J.; Moran, Conor; Almeida, Henrique V.; Kelly, Daniel J.; O'Brien, Fergal J.. "Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair". Materials Today Bio 12 (2021): 100173. http://dx.doi.org/10.1016/j.mtbio.2021.100173.
    Published • 10.1016/j.mtbio.2021.100173
  6. Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al. "Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation". ACS Applied Bio Materials 4 2 (2021): 1888-1899. http://dx.doi.org/10.1021/acsabm.0c01490.
    Published • 10.1021/acsabm.0c01490
  7. Abecasis, Bernardo; Canhão, Pedro G.M.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Gomes-Alves, Patrícia; Serra, Margarida; Alves, Paula M.. "Toward a Microencapsulated 3D hiPSC-Derived in vitro Cardiac Microtissue for Recapitulation of Human Heart Microenvironment Features". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.580744.
    Published • 10.3389/fbioe.2020.580744
  8. Cunniffe, G.M.; Díaz-Payno, P.J.; Sheehy, E.J.; Critchley, S.E.; Almeida, H.V.; Pitacco, P.; Carroll, S.F.; et al. "Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues". Biomaterials 188 (2019): 63-73. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056176967&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2018.09.044
  9. Almeida, Henrique V.; Dikina, Anna D.; Mulhall, Kevin J.; O’Brien, Fergal J.; Alsberg, Eben; Kelly, Daniel J.. "Porous Scaffolds Derived from Devitalized Tissue Engineered Cartilaginous Matrix Support Chondrogenesis of Adult Stem Cells". ACS Biomaterials Science & Engineering 3 6 (2017): 1075-1082. http://dx.doi.org/10.1021/acsbiomaterials.7b00019.
    Published • 10.1021/acsbiomaterials.7b00019
  10. Dikina, Anna D.; Almeida, Henrique V.; Cao, Meng; Kelly, Daniel J.; Alsberg, Eben. "Scaffolds Derived from ECM Produced by Chondrogenically Induced Human MSC Condensates Support Human MSC Chondrogenesis". ACS Biomaterials Science & Engineering 3 7 (2017): 1426-1436. http://dx.doi.org/10.1021/acsbiomaterials.6b00654.
    Published • 10.1021/acsbiomaterials.6b00654
  11. Almeida, Henrique V.; Sathy, Binulal N.; Dudurych, Ivan; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.; Almeida, H.V.; et al. "Anisotropic Shape-Memory Alginate Scaffolds Functionalized with Either Type I or Type II Collagen for Cartilage Tissue Engineering". Tissue Engineering Part a 23 1-2 (2017): 55-68. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000391740200006&KeyUID=WOS:000391740200006.
    10.1089/ten.tea.2016.0055
  12. Ronaldo J. F. C. do Amaral; Henrique V. Almeida; Daniel J. Kelly; Fergal J. O’Brien; Cathal J. Kearney. "Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy". Stem Cells International 2017 (2017): 1-10. https://doi.org/10.1155%2F2017%2F6843727.
    10.1155/2017/6843727
  13. Gouveia, P.J.; Rosa, S.; Ricotti, L.; Abecasis, B.; Almeida, H.V.; Monteiro, L.; Nunes, J.; et al. "Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes". Biomaterials 139 (2017): 213-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020728965&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2017.05.048
  14. Henrique V. Almeida; Kevin J. Mulhall; Fergal J. O'Brien; Daniel J. Kelly. "Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds". Journal of Tissue Engineering and Regenerative Medicine 11 11 (2016): 2979-2987. https://doi.org/10.1002%2Fterm.2199.
    10.1002/term.2199
  15. Almeida, H. V.; Eswaramoorthy, R.; Cunniffe, G. M.; Buckley, C. T.; O'Brien, F. J.; Kelly, Dj.. "Fibrin hydrogels functionalized with cartilage extracellular matrix and incorporating freshly isolated stromal cells as an injectable for cartilage regeneration". Acta Biomaterialia 36 (2016): 55-62. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375888000004&KeyUID=WOS:000375888000004.
    10.1016/j.actbio.2016.03.008
  16. Almeida, Henrique V.; Cunniffe, Grainne M.; Vinardell, Tatiana; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.. "Coupling Freshly Isolated CD44(+) Infrapatellar Fat Pad-Derived Stromal Cells with a TGF-3 Eluting Cartilage ECM-Derived Scaffold as a Single-Stage Strategy for Promoting Chondrogenesis". Advanced Healthcare Materials 4 7 (2015): 1043-1053. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000354481100011&KeyUID=WOS:000354481100011.
    10.1002/adhm.201400687
  17. Almeida, Henrique V.; Liu, Yurong; Cunniffe, Grainne M.; Mulhall, Kevin J.; Matsiko, Amos; Buckley, Conor T.; O'Brien, Fergal J.; Kelly, Daniel J.. "Controlled release of transforming growth factor-beta 3 from cartilage-extra-cellular-matrix-derived scaffolds to promote chondrogenesis of human-joint-tissue-derived stem cells". Acta Biomaterialia 10 10 (2014): 4400-4409. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342523800034&KeyUID=WOS:000342523800034.
    10.1016/j.actbio.2014.05.030
  18. Liu, Yurong; Buckley, Conor Timothy; Almeida, Henrique V.; Mulhall, Kevin J.; Kelly, Daniel John. "Infrapatellar Fat Pad-Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and Can be Used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions". Tissue Engineering Part a 20 21-22 (2014): 3050-3062. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344592600023&KeyUID=WOS:000344592600023.
    10.1089/ten.tea.2014.0035
Thesis / Dissertation
  1. Almeida, Henrique. "Cartilage extracellular matrix-derived scaffolds for joint regeneration". PhD, University of Dublin Trinity College, 2016. http://www.tara.tcd.ie/handle/2262/82890?show=full.
  2. Almeida, Henrique. "Synthesis and characterization of new biocompatible chitosan derivatives". Master, Universidade Nova de Lisboa, 2007.

Intellectual property

Patent
  1. 2020. "Method for making a porous scaffold suitable for use in repair of osseous, chondral, or osteochondral defects in a mammal".
    Granted/Issued
Provisional application for patent
  1. 2017. "A method for making a porous scaffold suitable for use in repair of osseous, chondral, or osteochondral defects in a mammal".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09 Unleashing the Potential of Laser-Induced Graphene for Cardiomyocyte Stimulation in Cardiac Tissue Engineering E-MRS
(Warsaw, Poland)
2021/11/15 Extracellular matrix functionalization of human induced pluripotent stem cell-based cardiac tissues improves cardiomyocyte maturation 5th TERMIS World Congress
TERMIS (Maastricht, Netherlands)
2019/05 ECM Functionalization of Stem Cell-Derived Cardiac 3D Spheroids TERMIS-EU 2019
TERMIS (Rhodes, Greece)
2019/05 Engineering 3D hiPSC-based Cardiac Tissues for Preclinical Research TERMIS-EU 2019
TERMIS (Rhodes, Greece)
2019/05 Extracellular-Matrix Functionalization of human iPSC-based cardiac tissues improves cardiomyocyte maturation SPCCTV 4D Visions
SPCCTV (Albufeira, Portugal)
2016/06/28 A bilayered scaffold derived from growth plate and articular cartilage extracellular matrix for osteochondral tissue regeneration in a caprine model TERMIS-EU 2016
TERMIS (Uppsala, Sweden)
2016/01 Regeneration of osteochondral defects by spatial modulation of endochondral ossification within engineered cartilage grafts Bioengineering in Ireland 22nd Annual Conference
(Galway, Ireland)
2016/01 A bi-phasic scaffold derived from growth plate & articular cartilage ECM for osteochondral defect repair in a caprine model Bioengineering in Ireland 22nd Annual Conference
(Galway, Ireland)
2016/01 Directed osteogenesis and chondrogenesis in a multi-layered osteochondral scaffold facilitates joint regeneration in a goat model using both cell-free and cell-seeded approaches Bioengineering in Ireland 22nd Annual Conference
(Galway, Ireland)
2015/01 Functionalizing fibrin hydrogels with cartilage ECM microparti-cles enhances chondrogenesis of human infrapatellar fat pad stem cells in vitro and in vivo Bioengineering in Ireland 21nd Annual Conference
(Maynooth, Ireland)
2015/01 Development of a bilayered decellularized extracellular matrix (ECM) derived scaffold for osteochondral tissue engineering Bioengineering in Ireland 21nd Annual Conference
(Maynooth, Ireland)
2014/06/10 Combining human infrapatellar fat pad stem cells with a growth factor releasing ECM-derived scaffold to develop a single-stage therapy for cartilage repair: in vitro and in vivo assessment TERMIS-EU 2014
TERMIS (Genoa, Italy)
2014/06/10 A co-culture of chondrons and infrapatellar-derived stem cells isolated from osteoarthritic joints enhances chondrogenesis in both normoxic and hypoxic environments TERMIS-EU 2014
TERMIS (Genoa, Italy)
2014/06/10 Layered decellularized extracellular matrix-derived scaffolds for osteochondral tissue engineering TERMIS-EU 2014
TERMIS (Genoa, Italy)
2014/01 An in vitro and in vivo assessment of a growth factor releasing cartilage ECM-derived scaffold seeded with infrapatellar fat pad stem cells for articular cartilage repair Bioengineering in Ireland 20nd Annual Conference
(Limerick, Ireland)
2014/01 The effect of oxygen tension on cartilage engineered using diseased human stem cells within ECM-derived scaffolds Bioengineering in Ireland 20nd Annual Conference
(Limerick, Ireland)
2014/01 Layered decellularized extracellular matrix (ECM) derived scaffolds for osteo-chondral defect regeneration Bioengineering in Ireland 20nd Annual Conference
(Limerick, Ireland)
2013/09 Optimizing cartilage extracellular matrix-derived scaffolds to act as growth factor delivery platforms to promote chondrogenesis of mesenchymal stem cells “Where Science meets Clinic” The symposium of AOER
AOER (Davos, Switzerland)
2013/01 Controlled release of TGF- ß3 from cartilage extra cellular matrix derived scaffolds induces robust chondrogenesis of diseased human stem cells Bioengineering in Ireland 19nd Annual Conference
(Co. Meath, Ireland)
2012/01 Combining freshly isolated CD271+ positive infrapatellar fat pad stem cells and a TGF-ß3 releasing scaffold to develop a single stage therapy for cartilage repair Bioengineering in Ireland 18nd Annual Conference
(Belfast, United Kingdom)
2012 Combining freshly isolated CD271+ infrapatellar fat pad stem cells and TGF-ß3 releasing scaffold to develop a single stage therapy for cartilage repair 3rd TERMIS World Congress
TERMIS (Vienna)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/09/01 - 2025/09/01 Skin interfaced graphene-based platforms for sweat analysis
Supervisor
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2022/12/01 - 2023/10/31 Estudo do impacto de diferentes materiais na deteção do CMV nos Dried blood spots; Study of the impact of different materials on CMV detection in Dried blood spots
Co-supervisor
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2023/02/01 - 2023/09/30 3D-Bioprinted Conductive Substrates for Cardiac Tissue Engineering
Supervisor
 Engenharia Biomédica (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 Nature-derived Conductive Scaffolds for Therapeutic Applications (Chitosan)
Supervisor
 Ciências de Engenharia de Micro e Nanotecnologias (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 Nature-derived Conductive Scaffolds for Therapeutic Applications (Collagen)
Supervisor
 Engenharia Biomédica (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/02/01 - 2023/09/30 ZrO2 Nanostructures on Anisotropic Alginate Scaffolds for Osteochondral Tissue Engineering
Supervisor
 Ciências de Engenharia de Micro e Nanotecnologias (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/01/01 - 2023/09/30 Biofabrication of Conductive and Magnetic Auxetic Materials for Cardiac Regeneration
Supervisor
 Enhenharia Biomédica e Biofísica (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2018 - 2022/07/05 Cell-based and cell-free strategies for cardiac repair (PD/BD/139078/2018)
Co-supervisor
 MIT-Portugal (PhD)
Instituto de Biologia Experimental e Tecnológica, Portugal
2018 - 2019 Engineering Extracellular Matrix-derived Constructs for Human Cardiac Tissue Models
Co-supervisor
 Engenharia Biomédica (Master)
Instituto de Biologia Experimental e Tecnológica, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/01/01 - 2023/03/05 VIII Annual Meeting - Jornadas i3N 2023 (https://www.i3n.org/viii-annual-meeting-jornadas-i3n-2023) (2023/03/03 - 2023/03/04)
Meeting (Member of the Organising Committee)
 Instituto de Nanoestruturas Nanomodelação e Nanofabricação, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/11 DEVELOPMENT OF NEW HYDROGEL BIOINKS FOR LIGHT-BASED BIOPRINTING 4D MATERIALS FOR ADDITIVE MANUFACTURING
(Thesis) Main arguer
 Vasco Teixeira (Master)
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2023/09 BIOPRINTING OF ENZYMATICALLY CROSSLINKED HYALURONIC ACIDGELATIN HYDROGELS
(Thesis) Main arguer
 TERESA DÍAZ JORDÀ (Master)
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
2023/05 POLY(IONIC LIQUID) DERIVED MATERIALS FOR TISSUE ENGINEERING APPLICATIONS
(Thesis) Main arguer
 Marta Alexandra de Oliveira Henriques (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/10 Design and fabrication of microgel shapes as red blood cell substitutes (RBCs) by UV-assisted punching
(Thesis) Main arguer
 MARIANA FILIPA DE ABREU ALVES (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/09 3D BIOPRINTED CONDUCTIVE HYDROGEL FOR OPTIMIZED SMOOTH MUSCLE TISSUE ENGINEERING
(Thesis) Main arguer
 CLÁUDIA VAZQUEZ PEREIRA (Master)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/07 Cryopreservation and cold storage of human induced pluripotent stem cell-derived cardiomyocytes
(Thesis) Main arguer
 Beatriz Assunção Gamelas (Other)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2022 The role of DAND5 in the coordination of hiPSC-derived cardiomyocyte environmental cues: their impact on cardiomyocyte electrophysiology
(Thesis) Main arguer
 Mafalda Dos Santos Marques Nunes (Master)
2022 Desenvolvimento de um modelo de epiderme 3D inflamada, in vitro, para avaliar a eficácia de compostos anti-inflamatórios; Development of an in vitro 3D inflamed epidermis model to evaluate the efficacy of anti-inflammatory compounds
(Thesis) Main arguer
 Madalena Celeiro Rei (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Association member

Society Organization name Role
2012 - Current TERMIS - Tissue Engineering and Regenerative Medicine International Society

Committee member

Activity description
Role 		Institution / Organization
2021/09/01 - Current ITQB/iBET Postdoctoral Association (PDA) - The ITQB/iBET Postdoctoral Association (PDA) represents and supports interests of the early career researchers working at Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA) and at Instituto de Biologia Experimental e Tecnológica (iBET). The PDA exists to promote a sense of community among the early career researchers, to organise activities that enhance professional and personal development, to organise networking and career development events.
Coordinator
 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Biosensors Universidade Nova de Lisboa, Portugal
2022 - Current Introduction to Material Science & Engineering Universidade Nova de Lisboa, Portugal
2022 - Current Nanofabrication & Characterization of Biomaterials Universidade Nova de Lisboa, Portugal
2022 - Current Introduction to Micro & Nanotechnology Universidade Nova de Lisboa, Portugal
2011 - 2015 Biomaterials Mechanical Engineering (Master) University of Dublin Trinity College, Ireland
Distinctions

Other distinction

2021 Stimulus of Scientific Employment, Individual Support (CEECIND) - 3rd Edition
Fundação para a Ciência e a Tecnologia, Portugal
2019 Bioengineering of 3D-Bioprinted Constructs for Cardiac Tissue Engineering (3DBioPrintCTE) - iBETXplore starting grant, 2019.
Instituto de Biologia Experimental e Tecnológica, Portugal
2017 Postdoctoral Fellowship (SFRH/BPD/120595/2016)
Fundação para a Ciência e a Tecnologia, Portugal
2014 2nd Prize in PhD Student Category for Annual Symposium
University of Dublin Trinity College, Ireland
2013 CRANN Commercialization Award (1)
2013 CRANN Commercialization Award (2)
2011 Graduate Research Education Program (GREP-Eng) in Engineering funding award
University of Dublin Trinity College, Ireland

European Regional Development Fund, Belgium
2007 Student with the highest score for Master degree in Material Science and Engineering
Universidade Nova de Lisboa, Portugal