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Filipe Castro. Completed the Doutoramento in PhD Biomedical Sciences (GABBA) in 2004/10/13 by Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar and Graduated in Biologia in 1996/09/10 by Universidade do Porto Faculdade de Ciências. Is Assistant Professor in Universidade do Porto Faculdade de Ciências. Published 165 articles in journals. Has 2 section(s) of books and 2 book(s). Organized 1 event(s). Participated in 1 event(s). Supervised 5 PhD thesis(es) e co-supervised 6. Supervised 4 MSc dissertation(s) e co-supervised 3. Participates and/or participated as Other in 1 project(s), Principal investigator in 4 project(s) and Researcher in 7 project(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Zoology, Evolutionary Biology, and Environmental Sciences. In their professional activities interacted with 584 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Genomics, Gene loss; Marine Sciences and Technologies; Part of the International Editorial Board of Comparative Biochemistry and Physiology (https://www.sciencedirect.com/journal/comparative-biochemistry-and-physiology-part-a-molecular-and-integrative-physiology/about/editorial-board); Council Member of the European Society of Comparative Endocrinology.
Identificação

Identificação pessoal

Nome completo
Filipe Castro
Género
Masculino

Nomes de citação

  • C. Castro, L. Filipe

Identificadores de autor

Ciência ID
941D-C777-CC18
ORCID iD
0000-0001-7697-386X
Scopus Author Id
16644781000

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Zoologia
  • Ciências Naturais - Ciências Biológicas - Biologia da Evolução das Espécies
  • Ciências Naturais - Ciências Biológicas - Biologia Marinha
  • Ciências Naturais - Ciências da Terra e do Ambiente - Ciências do Ambiente

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Formação
Grau Classificação
2004/10/13
Concluído
PhD Biomedical Sciences (GABBA) (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Organisation and evolution of the ANTP class of homeobox genes: insights from amphioxus" (TESE/DISSERTAÇÃO)
Approved
1996/09/10
Concluído
Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"N/a" (TESE/DISSERTAÇÃO)
15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2005/12/01 - 2019/12/31 Investigador Auxiliar (carreira) (Investigação) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2004/11/01 - 2005/11/01 Pós-doutorado (Investigação) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
1999/09/01 - 2000/08 Estagiário de Investigação (Investigação) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2019/11/01 - Atual Professor Auxiliar (Docente Universitário) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2013/12/01 - 2019/09/30 Professor Auxiliar (Docente Universitário) Universidade do Porto Faculdade de Ciências, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2013/01/01 - 2018/12/31 Member of the Board of Directors Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2000/09/01 - 2004/10/13 PhD Student GABBA Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
(...)
1997/04/01 - 1998/09/01 Assistant researcher Universidade do Porto Centro de Investigação em Biodiversidade e Recursos Genéticos, Portugal
Projetos

Bolsa

Designação Financiadores
2008/10 - 2012/06 An integrative study on the toxicopathic lesions in Portuguese estuarine fishes - Assessing injury impact and toxicogenomic implications in experimental models.
PTDC/MAR/70436/2006
Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2023/09/01 - 2026/08/31 Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches – Marma-detox
334739
PI of the Portuguese Team
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Em curso
2022/01/01 - 2024/12/31 Sustainable antifouling agents: from grape wastes to the sea with the green chemistry leading the way.
PTDC/CTA-AMB/0853/2021
Universidade do Porto Faculdade de Farmácia, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/04/01 - 2024/03/31 Mineração do mar profundo e alterações climáticas: novas ferramentas de modelação no suporte à gestão de risco ambiental
PTDC/CTA-AMB/7948/2020
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Instituto Português do Mar e da Atmosfera, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/03/01 - 2024/02/29 Bivalves no limite: genómica da adaptação em cenários de alteraçoes climáticas
PTDC/CTA-AMB/3065/2020
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade do Minho, Portugal

Université de Montréal, Canadá

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Investigação em Biodiversidade e Biologia Evolutiva, Portugal

Instituto Politécnico de Bragança, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/11/01 - 2022/10/31 Trans-phyletic obesogenic responses: from epigenetic modules to transgenerational environmental impacts
PTDC/CTA-AMB/31544/2017
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/03/16 - 2022/09/15 Anti-incrustantes sustentáveis: dos desperdícios da uva para o Mar, com a Química Verde a liderar o caminho.
PTDC/CTA-AMB/0853/2021
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/03/16 - 2022/09/15 NIAF- Sustainable antifouling agents: from grape wastes to the sea with the green chemistry leading the way
PTDC/CTA-AMB/0853/2021
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/10/15 - 2021/10/14 Applying elasmobranch immunogenetics to fisheries management and the study of vertebrate adaptive immunity
PTDC/ASP-PES/28053/2017
Investigador
Universidade do Porto Centro de Investigação em Biodiversidade e Recursos Genéticos, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/08/01 - 2021/07/31 Unraveling neuro-endocrine/immune modulatory roles of tryptophan during inflammation
PTDC/CVT-CVT/32349/2017
Investigador
2018/07/26 - 2021/07/25 Biosensor and biomimetic recognition element based devices for detection and separation of cyanobacteria metabolites with ecotoxicological and therapeutical applications
PTDC/BTA-GES/32359/2017
Investigador
2018/07/02 - 2021/07/01 Understanding Darwinian cancer evolution at the single-cell level
PTDC/BIA-EVL/32030/2017
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
2018/07 - 2021/07 EvoDis - The Metazoan Endocrine System in the Anthropocene Epoch: from EVOlution to DISruption,
PTDC/CTA-AMB/31342/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
2018/06/18 - 2021/05/31 The Sea and the Shore, Architecture and Marine Biology: The Impact of Sea Life on the Built Environment
PTDC/ART-DAQ/29537/2017
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/06/01 - 2021/05/31 Impacts of global change on environmentally realistic mixtures of endocrine disruptor compounds on the structure and functioning of coastal ecosystems ? Implications for a sustainable environment
PTDC/BIA-ECO/30552/2017
Investigador
2016/01 - 2018/12 CORAL - Sustainable ocean exploitation: tools and sensors
NORTE-01-0145-FEDER-000036
Investigador responsável
2011/04/01 - 2014/09/30 Estudo da modelação das vias de sinalização dos retinóides e das hormonas da tiróide, por disruptores endócrinos, em invertebrados
PTDC/MAR/115199/2009
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/04/01 - 2014/09/30 Peroxissomas, estrogénios e receptores nucleares: avaliação de "cross-talk" nos hepatócitos da truta como modelo animal - impactos no metabolismo lipídico.
PTDC/CVT/115618/2009
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/04/01 - 2013/09/30 The invertebrate repertoire of nuclear receptors: evolutionary and endocrine disruption insights
Investigador responsável
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
2010/04/01 - 2013/09/30 O repertório de receptores nucleares em invertebrados: investigações evolutivas e de disrupção endócrina
PTDC/MAR/105199/2008
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 15 - 2011-2012
PEst-C/MAR/LA0015/2011
Centro de Ciências do Mar, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/09/01 - 2012/05/31 The modulation of retinoic acid signalling pathways by environmental pollutants in teleosts
PTDC/MAR/68106/2006
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/08/01 - 2012/01/31 Disrupção do metabolismo lipídico em peixes marinhos por xenobióticos ligandos de receptores activados por proliferadores peroxissomais PPARs
PTDC/MAR/68885/2006
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2005/10/01 - 2008/09/30 The molecular mechanisms of sexual differentiation in gastropods and the role of vertebrate-like steroid hormones
POCI/MAR/59462/2004
Investigador responsável
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
2005/10/01 - 2007/06/30 Efeito de misturas complexas de disruptores endócrinos com actividade antagónica em duas espécies de peixes com diferentes ciclos de vida
POCI/MAR/60895/2004
Instituto Universitário de Ciências Psicológicas Sociais e da Vida, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2011/09/01 - 2012/10/30 Peroxisomes, estrogens, and nuclear receptors: cross-talk evaluation in hepatocytes of the trout as a fish model organism - impacts on lipid metabolism
PTDC/CVT/115618/2009
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. da Fonseca, Rute R.; Campos, Paula F.; Rey-Iglesia, Alba; Barroso, Gustavo V.; Bergeron, Lucie A.; Nande, Manuel; Tuya, Fernando; et al. "Population Genomics Reveals the Underlying Structure of the Small Pelagic European Sardine and Suggests Low Connectivity within Macaronesia". Genes 15 2 (2024): 170. http://dx.doi.org/10.3390/genes15020170.
    10.3390/genes15020170
  2. Ana Veríssimo; L Filipe C Castro; Antonio Muñoz-Mérida; Tereza Almeida; Arnaud Gaigher; Fabiana Neves; Martin F Flajnik; Yuko Ohta; Meredith Yeager. "An Ancestral Major Histocompatibility Complex Organization in Cartilaginous Fish: Reconstructing MHC Origin and Evolution". Molecular Biology and Evolution (2023): https://doi.org/10.1093/molbev/msad262.
    10.1093/molbev/msad262
  3. André Gomes-dos-Santos; Nair Vilas-Arrondo; André M. Machado; Esther Román-Marcote; Jose Luís Del Río Iglesias; Francisco Baldó; Montse Pérez; et al. "Mitochondrial replication's role in vertebrate mtDNA strand asymmetry". Open Biology (2023): https://doi.org/10.1098/rsob.230181.
    10.1098/rsob.230181
  4. Ana Matos; André Gomes-dos-Santos; Sofia Graça Aranha; Ester Dias; Ana Veríssimo; Alexandra Teodósio; Ivone Figueiredo; L. Filipe C. Castro; Elsa Froufe. "Dataset of the complete mitogenome of the deep-sea sailfin roughshark, Oxynotus paradoxus Frade, 1929". Data in Brief (2023): https://doi.org/10.1016/j.dib.2023.109836.
    10.1016/j.dib.2023.109836
  5. Bernardo Pinto; Machado AM; J.Miguel Cordeiro; Kolbadinezhad SM; Elza Fonseca; Andrade JP; Palma J; et al. "Extensive gene loss parallels kidney aglomerulism in Syngnathidae.". Current biology : CB (2023): https://doi.org/10.1016/j.cub.2023.08.045.
    10.1016/j.cub.2023.08.045
  6. Alberto Ribes-Navarro; Naoki Kabeya; L. Filipe C. Castro; André Gomes-dos-Santos; Miguel M. Fonseca; Hilke Alberts-Hubatsch; Francisco Hontoria; Juan C. Navarro; Óscar Monroig. "Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species". Open Biology (2023): https://doi.org/10.1098/rsob.230196.
    10.1098/rsob.230196
  7. Bernardo Pinto; Raul Valente; Filipe Caramelo; Raquel Ruivo; L. Filipe C. Castro. "Decay of Skin-Specific Gene Modules in Pangolins". Journal of Molecular Evolution (2023): https://doi.org/10.1007/s00239-023-10118-z.
    10.1007/s00239-023-10118-z
  8. André Gomes-dos-Santos; Elsa Froufe; John M. Pfeiffer; Nathan A. Johnson; Chase H. Smith; André M. Machado; L. Filipe C. Castro; et al. "A novel assembly pipeline and functional annotations for targeted sequencing: A case study on the globally threatened Margaritiferidae (Bivalvia: Unionida)". Molecular Ecology Resources (2023): https://doi.org/10.1111/1755-0998.13802.
    10.1111/1755-0998.13802
  9. André Gomes-dos-Santos; Manuel Lopes-Lima; André M. Machado; Thomas Forest; Guillaume Achaz; Amílcar Teixeira; Vincent Prié; L. Filipe C. Castro; Elsa Froufe. "The Crown Pearl V2: an improved genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758)". Gigabyte (2023): https://doi.org/10.46471/gigabyte.81.
    10.46471/gigabyte.81
  10. Inês Páscoa; Rita Biltes; João Sousa; Marco Aurélio Correia Preto; Vitor Vasconcelos; Luís Filipe Castro; Raquel Ruivo; Isabel Cunha. "A Multiplex Molecular Cell-Based Sensor to Detect Ligands of PPARs: An Optimized Tool for Drug Discovery in Cyanobacteria". Sensors (2023): https://doi.org/10.3390/s23031338.
    10.3390/s23031338
  11. Malzahn, AM; Villena Rodriguez, A; Monroig, O; Johansen, A; Castro, LFC; Navarro, JC; Hagemann, A. "Diet rather than temperature determines the biochemical composition of the ragworm Hediste diversicolor (OF Muller, 1776) (Annelida: Nereidae)". AQUACULTURE (2023):
    10.1016/j.aquaculture.2023.739368
  12. Sun, B; Huang, YW; Castro, LFC; Yang, S; Huang, SQ; Jin, W; Zhou, H; et al. "The chromosome-level genome and key genes associated with mud-dwelling behavior and adaptations of hypoxia and noxious environments in loach (Misgurnus anguillicaudatus)". BMC BIOLOGY (2023):
    10.1186/s12915-023-01517-1
  13. Mucientes, G; Vilas Arrondo, N; Secci Petretto, G; Vázquez, U; Pin, X; López, A; Castro, LFC; Froufe, E. "First Confirmed Record of the Smalltooth Sand Tiger, Odontapis Ferox, in Galicia (NW Spain)". THALASSAS (2023):
    10.1007/s41208-023-00526-9
  14. Gomes-dos-Santos, A; Froufe, E; Machado, AM; Lajtner, J; Cernecky, J; Castro, LFC; Lima, ML. "A PacBio Hi-Fi Genome Assembly of the Painter's Mussel Unio pictorum (Linnaeus, 1758)". GENOME BIOLOGY AND EVOLUTION (2023):
    10.1093/gbe/evad116
  15. Froufe, E; Gomes dos Santos, A; Matos, A; Wilson, J; Malakpourkolbadinezhad, S; Pereira, DD; Singer, R; Castro, LFC. "How complex is the hidden species diversity of the teleost Plotosus genus?". ICHTHYOLOGICAL RESEARCH (2023):
    10.1007/s10228-023-00924-2
  16. Dias, E; Dromby, M; Ferreira, R; Gil, A; Tejerina, R; Castro, LFC; Rosso, M; et al. "Trophic ecology of common bottlenose dolphins in a pelagic insular environment inferred by stable isotopes". HYDROBIOLOGIA (2023):
    10.1007/s10750-023-05294-4
  17. "Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions". Progress in Lipid Research 86 (2022): 101157-101157. http://dx.doi.org/10.1016/j.plipres.2022.101157.
    10.1016/j.plipres.2022.101157
  18. "The era of reference genomes in conservation genomics". Trends in Ecology & Evolution 37 3 (2022): 197-202. http://dx.doi.org/10.1016/j.tree.2021.11.008.
    10.1016/j.tree.2021.11.008
  19. "Neuroendocrine pathways at risk? Simvastatin induces inter and transgenerational disruption in the keystone amphipod Gammarus locusta". Aquatic Toxicology 244 (2022): 106095-106095. http://dx.doi.org/10.1016/j.aquatox.2022.106095.
    10.1016/j.aquatox.2022.106095
  20. Machado, André M.; Gomes-dos-Santos, André; Fonseca, Miguel M.; da Fonseca, Rute R.; Veríssimo, Ana; Felício, Mónica; Capela, Ricardo; et al. "A genome assembly of the Atlantic chub mackerel (Scomber colias): a valuable teleost fishing resource". Gigabyte 2022 (2022): 1-21. http://dx.doi.org/10.46471/gigabyte.40.
    10.46471/gigabyte.40
  21. P. Ferreira; G. T. Kwan; S. Haldorson; J. L. Rummer; F. Tashiro; L. F. C. Castro; M. Tresguerres; J. M. Wilson. "A multi-tasking stomach: functional coexistence of acid–peptic digestion and defensive body inflation in three distantly related vertebrate lineages". Biology Letters (2022): https://doi.org/10.1098/rsbl.2021.0583.
    10.1098/rsbl.2021.0583
  22. "Biofortified Diets Containing Algae and Selenised Yeast: Effects on Growth Performance, Nutrient Utilization, and Tissue Composition of Gilthead Seabream (Sparus aurata)". Frontiers in Physiology 12 (2022): http://dx.doi.org/10.3389/fphys.2021.812884.
    10.3389/fphys.2021.812884
  23. Inês Páscoa; Elza Fonseca; Renato Ferraz; André M. Machado; Francisca Conrado; Raquel Ruivo; Isabel Cunha; Luís Filipe C. Castro. "The Preservation of PPAR¿ Genome Duplicates in Some Teleost Lineages: Insights into Lipid Metabolism and Xenobiotic Exploitation". Genes (2022): https://doi.org/10.3390/genes13010107.
    10.3390/genes13010107
  24. Machado, A.M.; Fernández-Boo, S.; Nande, M.; Pinto, R.; Costas, B.; Castro, L.F.C.. "The male and female gonad transcriptome of the edible sea urchin, Paracentrotus lividus: Identification of sex-related and lipid biosynthesis genes". Aquaculture Reports 22 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85119052510&partnerID=MN8TOARS.
    10.1016/j.aqrep.2021.100936
  25. Esfandiyari, K; Pfeifer, LJ; Farahani, MA; Kolbadinezhad, SM; Castro, LF; Wilson, JM. "The gastric proton pump in gobiid and mudskipper fishes. Evidence of stomach loss?". COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2022):
    10.1016/j.cbpa.2022.111300
  26. Gomes dos Santos, A; Machado, AM; Castro, LFC; Prie, V; Teixeira, A; Lopes Lima, M; Froufe, E. "The gill transcriptome of threatened European freshwater mussels". SCIENTIFIC DATA (2022):
    10.1038/s41597-022-01613-x
  27. Ferraz, RB; Paixao, RV; Lopes-Marques, M; Machado, AM; Salaro, AL; Castro, LFC; Monroig, O; O'Sullivan, FLA. "The repertoire of the elongation of very long-chain fatty acids (Elovl) protein family is conserved in tambaqui (Colossoma macropomum): Gene expression profiles offer insights into the sexual differentiation process". COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2022):
    10.1016/j.cbpb.2022.110749
  28. Zhao, Y; Castro, LFC; Monroig, O; Cao, XJ; Sun, YH; Gao, J. "A zebrafish ppar gamma gene deletion reveals a protein kinase network associated with defective lipid metabolism". FUNCTIONAL & INTEGRATIVE GENOMICS (2022):
    10.1007/s10142-022-00839-7
  29. Nande, M; Monroig, O; Machado, AM; Castro, LFC; Lopes-Marques, M; Capitao, A; Navarro, JC. "Dietary lipids as modulators of fatty acid profile and gene expression patterns on body compartments of Octopus vulgaris paralarvae". AQUACULTURE (2022):
    10.1016/j.aquaculture.2022.738293
  30. Vilas Arrondo, N; Gomes dos Santos, A; Perez, M; Baldo, F; Verissimo, A; Catarino, D; Machado, AM; et al. "A mitochondrial genome assembly of the opal chimaera, Chimaera opalescens Luchetti, Iglesias et Sellos 2011, using PacBio HiFi long reads". MITOCHONDRIAL DNA PART B-RESOURCES (2022):
    10.1080/23802359.2022.2044403
  31. Raquel Ruivo; João Sousa; Teresa Neuparth; Olivier Geffard; Arnaud Chaumot; L. Filipe C. Castro; Davide Degli-Esposti; Miguel M. Santos. "From Extrapolation to Precision Chemical Hazard Assessment: The Ecdysone Receptor Case Study". Toxics (2021): https://doi.org/10.3390/toxics10010006.
    10.3390/toxics10010006
  32. Raul Valente; Filipe Alves; Isabel Sousa-Pinto; Raquel Ruivo; L. Filipe C. Castro; Isabel Sousa Pinto. "Functional or Vestigial? The Genomics of the Pineal Gland in Xenarthra". Journal of Molecular Evolution (2021): https://doi.org/10.1007/s00239-021-10025-1.
    10.1007/s00239-021-10025-1
  33. Shouxiang Sun; Yumei Wang; Pei-Tian Goh; Mónica Lopes-Marques; L. Filipe C. Castro; Óscar Monroig; Meng-Kiat Kuah; et al. "Evolution and Functional Characteristics of the Novel elovl8 That Play Pivotal Roles in Fatty Acid Biosynthesis". Genes (2021): https://doi.org/10.3390/genes12081287.
    10.3390/genes12081287
  34. Tereza Almeida; Yuko Ohta; Arnaud Gaigher; Antonio Muñoz-Mérida; Fabiana Neves; L. Filipe C. Castro; André M. Machado; et al. "A Highly Complex, MHC-Linked, 350 Million-Year-Old Shark Nonclassical Class I Lineage". The Journal of Immunology (2021): ji2000851-ji2000851. https://doi.org/10.4049/jimmunol.2000851.
    10.4049/jimmunol.2000851
  35. Bárbara Matos; Stephen J. Publicover; Luis Filipe C. Castro; Pedro J. Esteves; Margarida Fardilha. "Brain and testis: more alike than previously thought?". Open Biology (2021): https://doi.org/10.1098/rsob.200322.
    10.1098/rsob.200322
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  146. Castro, L.F.C.; Lobo-da-Cunha, A.; Rocha, M.J.; Urbatzka, R.; Rocha, E.. "Pex11a in brown trout (Salmo trutta f. fario): Expression dynamics during the reproductive cycle reveals sex-specific seasonal patterns". Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology 164 1 (2013): 207-214. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870253034&partnerID=MN8TOARS.
    10.1016/j.cbpa.2012.09.003
  147. Urbatzka, R.; Galante-Oliveira, S.; Rocha, E.; Castro, L.F.C.; Cunha, I.. "Normalization strategies for gene expression studies by real-time PCR in a marine fish species, Scophthalmus maximus". Marine Genomics 10 (2013): 17-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877664667&partnerID=MN8TOARS.
    10.1016/j.margen.2013.02.001
  148. Urbatzka, R.; Galante-Oliveira, S.; Rocha, E.; Castro, L.F.C.; Cunha, I.. "Tissue expression of PPAR-alpha isoforms in Scophthalmus maximus and transcriptional response of target genes in the heart after exposure to WY-14643". Fish Physiology and Biochemistry 39 4 (2013): 1043-1055. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879843607&partnerID=MN8TOARS.
    10.1007/s10695-012-9761-7
  149. Carneiro, J.; Duarte-Pereira, S.; Azevedo, L.; Castro, L.F.C.; Aguiar, P.; Moreira, I.S.; Amorim, A.; Silva, R.M.. "The Evolutionary Portrait of Metazoan NAD Salvage". PLoS ONE 8 5 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84878391235&partnerID=MN8TOARS.
    10.1371/journal.pone.0064674
  150. Philip, S.; Castro, L.F.C.; Da Fonseca, R.R.; Reis-Henriques, M.A.; Vasconcelos, V.; Santos, M.M.; Antunes, A.. "Adaptive evolution of the Retinoid X receptor in vertebrates". Genomics 99 2 (2012): 81-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856458490&partnerID=MN8TOARS.
    10.1016/j.ygeno.2011.12.001
  151. Costa, J.; Reis-Henriques, M.A.; Castro, L.F.C.; Ferreira, M.. "ABC transporters, CYP1A and GSTa gene transcription patterns in developing stages of the Nile tilapia (Oreochromis niloticus)". Gene 506 2 (2012): 317-324. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864568459&partnerID=MN8TOARS.
    10.1016/j.gene.2012.06.092
  152. Costa, J.; Reis-Henriques, M.A.; Castro, L.F.C.; Ferreira, M.. "Gene expression analysis of ABC efflux transporters, CYP1A and GSTa in Nile tilapia after exposure to benzo(a)pyrene". Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 155 3 (2012): 469-482. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858794993&partnerID=MN8TOARS.
    10.1016/j.cbpc.2011.12.004
  153. Castro, L.F.; Monroig, O.; Leaver, M.J.; Wilson, J.; Cunha, I.; Tocher, D.R.. "Functional desaturase Fads1 (¿5) and Fads2 (¿6) orthologues evolved before the origin of jawed vertebrates.". PloS one 7 2 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865314614&partnerID=MN8TOARS.
    10.1371/journal.pone.0031950
  154. Castro, L.F.C.; Lopes-Marques, M.; Wilson, J.M.; Rocha, E.; Reis-Henriques, M.A.; Santos, M.M.; Cunha, I.. "A novel Acetyl-CoA synthetase short-chain subfamily member 1 (Acss1) gene indicates a dynamic history of paralogue retention and loss in vertebrates". Gene 497 2 (2012): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862829496&partnerID=MN8TOARS.
    10.1016/j.gene.2012.01.013
  155. Gesto, M.; Castro, L.F.C.; Reis-Henriques, M.A.; Santos, M.M.. "Tissue-specific distribution patterns of retinoids and didehydroretinoids in rainbow trout Oncorhynchus mykiss". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 161 1 (2012): 69-78. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856482907&partnerID=MN8TOARS.
    10.1016/j.cbpb.2011.09.006
  156. Castro, L.F.C.; Lopes-Marques, M.; Gonçalves, O.; Wilson, J.M.. "The evolution of pepsinogen C genes in vertebrates: Duplication, loss and functional diversification". PLoS ONE 7 3 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84863247989&partnerID=MN8TOARS.
    10.1371/journal.pone.0032852
  157. Soares, J.; Castro, L.F.C.; Reis-Henriques, M.A.; Monteiro, N.M.; Santos, M.M.. "Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways". Ecotoxicology 21 5 (2012): 1513-1522. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864965676&partnerID=MN8TOARS.
    10.1007/s10646-012-0905-4
  158. Abidli, S.; Santos, M.M.; Lahbib, Y.; Castro, L.F.C.; Reis-Henriques, M.A.; Trigui El Menif, N.. "Tributyltin (TBT) effects on Hexaplex trunculus and Bolinus brandaris (Gastropoda: Muricidae): Imposex induction and sex hormone levels insights". Ecological Indicators 13 1 (2012): 13-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-80955181064&partnerID=MN8TOARS.
    10.1016/j.ecolind.2011.05.001
  159. Ribeiro, C.; Urbatzka, R.; Castro, L.F.C.; Carrola, J.; Fontainhas-Fernandes, A.; Monteiro, R.A.F.; Rocha, E.; Rocha, M.J.. "In vitro exposure of Nile tilapia (Oreochromis niloticus) testis to estrogenic endocrine disrupting chemicals: mRNA expression of genes encoding steroidogenic enzymes". Toxicology Mechanisms and Methods 22 1 (2012): 47-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455166345&partnerID=MN8TOARS.
    10.3109/15376516.2011.593053
  160. Gesto, M.; Castro, L.F.C.; Reis-Henriques, M.A.; Santos, M.M.. "Retinol metabolism in the mollusk osilinus lineatus indicates an ancient origin for retinyl ester storage capacity". PLoS ONE 7 4 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84859514628&partnerID=MN8TOARS.
    10.1371/journal.pone.0035138
  161. Coelho, I.; Lima, D.; André, A.; Melo, C.; Ruivo, R.; Reis-Henriques, M.A.; Santos, M.M.; Castro, L.F.C.. "Molecular characterization of Adh3 from the mollusc Nucella lapillus: Tissue gene expression after tributyltin and retinol exposure". Journal of Molluscan Studies 78 4 (2012): 343-348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868033168&partnerID=MN8TOARS.
    10.1093/mollus/eys018
  162. Theunissen, T.W.; Costa, Y.; Radzisheuskaya, A.; van Oosten, A.L.; Lavial, F.; Pain, B.; Castro, L.F.C.; Silva, J.C.R.. "Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain". Development 138 22 (2011): 4853-4865. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054906800&partnerID=MN8TOARS.
    10.1242/dev.068775
  163. Neves, J.V.; Wilson, J.M.; Kuhl, H.; Reinhardt, R.; Castro, L.F.C.; Rodrigues, P.N.S.. "Natural history of SLC11 genes in vertebrates: Tales from the fish world". BMC Evolutionary Biology 11 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79955087907&partnerID=MN8TOARS.
    10.1186/1471-2148-11-106
  164. Castro, L.F.C.; Wilson, J.M.; Gonçalves, O.; Galante-Oliveira, S.; Rocha, E.; Cunha, I.. "The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates". BMC Evolutionary Biology 11 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79956002928&partnerID=MN8TOARS.
    10.1186/1471-2148-11-132
  165. Lima, D; Reis Henriques, MA; Silva, R; Santos, AI; Castro, LFC; Santos, MM. "Tributyltin-induced imposex in marine gastropods involves tissue-specific modulation of the retinoid X receptor". AQUATIC TOXICOLOGY (2011):
    10.1016/j.aquatox.2010.09.022
  166. Sarria, MP; Soares, J; Vieira, MN; Filipe, L; Castro, C; Santos, MM; Monteiro, NM. "Rapid-behaviour responses as a reliable indicator of estrogenic chemical toxicity in zebrafish juveniles". CHEMOSPHERE (2011):
    10.1016/j.chemosphere.2011.07.0.48
  167. Castro, L.F.C.; Rocha, M.J.; Lobo-da-Cunha, A.; Batista-Pinto, C.; Machado, A.; Rocha, E.. "The 17ß-hydroxysteroid dehydrogenase 4: Gender-specific and seasonal gene expression in the liver of brown trout (Salmo trutta f. fario)". Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology 153 2 (2009): 157-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-66949137818&partnerID=MN8TOARS.
    10.1016/j.cbpb.2009.02.015
  168. Batista-Pinto, C.; Rocha, E.; Castro, L.F.C.; Rodrigues, P.; Lobo-da-Cunha, A.. "Seasonal and gender variation of peroxisome proliferator activated receptors expression in brown trout liver". General and Comparative Endocrinology 161 1 (2009): 146-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749117732&partnerID=MN8TOARS.
    10.1016/j.ygcen.2008.11.019
  169. Ferreira, F.; Santos, M.M.; Castro, L.F.C.; Reis-Henriques, M.A.; Lima, D.; Vieira, M.N.; Monteiro, N.M.. "Vitellogenin gene expression in the intertidal blenny Lipophrys pholis: A new sentinel species for estrogenic chemical pollution monitoring in the European Atlantic coast?". Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 149 1 (2009): 58-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-56949104846&partnerID=MN8TOARS.
    10.1016/j.cbpc.2008.07.002
  170. Santos, M.M.; Enes, P.; Reis-Henriques, M.A.; Kuballa, J.; Castro, L.F.C.; Vieira, M.N.. "Organotin levels in seafood from Portuguese markets and the risk for consumers". Chemosphere 75 5 (2009): 661-666. http://www.scopus.com/inward/record.url?eid=2-s2.0-64149118377&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2008.12.066
  171. Soares, J.; Coimbra, A.M.; Reis-Henriques, M.A.; Monteiro, N.M.; Vieira, M.N.; Oliveira, J.M.A.; Guedes-Dias, P.; et al. "Disruption of zebrafish (Danio rerio) embryonic development after full life-cycle parental exposure to low levels of ethinylestradiol". Aquatic Toxicology 95 4 (2009): 330-338. http://www.scopus.com/inward/record.url?eid=2-s2.0-71849083390&partnerID=MN8TOARS.
    10.1016/j.aquatox.2009.07.021
  172. Kortner, T.M.; Rocha, E.; Silva, P.; Castro, L.F.C.; Arukwe, A.. "Genomic approach in evaluating the role of androgens on the growth of Atlantic cod (Gadus morhua) previtellogenic oocytes". Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics 3 3 (2008): 205-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-47849111881&partnerID=MN8TOARS.
    10.1016/j.cbd.2008.04.001
  173. Santos, M.M.; Reis-Henriques, M.A.; Guillot, R.; Lima, D.; Franco-Duarte, R.; Mendes, I.; Queirós, S.; Castro, L.F.C.. "Anti-androgenic effects of sewage treatment plant effluents in the prosobranch gastropod Nucella lapillus". Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 148 1 (2008): 87-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-44149107048&partnerID=MN8TOARS.
    10.1016/j.cbpc.2008.03.012
  174. Castro, L.F.C.; Lima, D.; Machado, A.; Melo, C.; Hiromori, Y.; Nishikawa, J.; Nakanishi, T.; Reis-Henriques, M.A.; Santos, M.M.. "Imposex induction is mediated through the Retinoid X Receptor signalling pathway in the neogastropod Nucella lapillus". Aquatic Toxicology 85 1 (2007): 57-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548665935&partnerID=MN8TOARS.
    10.1016/j.aquatox.2007.07.016
  175. Castro, L.F.C.; Melo, C.; Guillot, R.; Mendes, I.; Queirós, S.; Lima, D.; Reis-Henriques, M.A.; Santos, M.M.. "The estrogen receptor of the gastropod Nucella lapillus: Modulation following exposure to an estrogenic effluent?". Aquatic Toxicology 84 4 (2007): 465-468. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548252418&partnerID=MN8TOARS.
    10.1016/j.aquatox.2007.07.008
  176. Gonçalves, A.F.; Castro, L.F.C.; Pereira-Wilson, C.; Coimbra, J.; Wilson, J.M.. "Is there a compromise between nutrient uptake and gas exchange in the gut of Misgurnus anguillicaudatus, an intestinal air-breathing fish?". Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics 2 4 (2007): 345-355. http://www.scopus.com/inward/record.url?eid=2-s2.0-35648978869&partnerID=MN8TOARS.
    10.1016/j.cbd.2007.08.002
  177. Alexandrino, P.; Faria, R.; Linhares, D.; Castro, F.; Le Corre, M.; Sabatié, R.; Baglinière, J.L.; Weiss, S.. "Interspecific differentiation and intraspecific substructure in two closely related clupeids with extensive hybridization, Alosa alosa and Alosa fallax". Journal of Fish Biology 69 SUPPL. B (2006): 242-259. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845538905&partnerID=MN8TOARS.
    10.1111/j.1095-8649.2006.01289.x
  178. Castro, L.F.C.; Rasmussen, S.L.K.; Holland, P.W.H.; Holland, N.D.; Holland, L.Z.. "A Gbx homeobox gene in amphioxus: Insights into ancestry of the ANTP class and evolution of the midbrain/hindbrain boundary". Developmental Biology 295 1 (2006): 40-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745887790&partnerID=MN8TOARS.
    10.1016/j.ydbio.2006.03.003
  179. Minguillón, C.; Gardenyes, J.; Serra, E.; Castro, L.F.; Hill-Force, A.; Holland, P.W.; Amemiya, C.T.; Garcia-Fernàndez, J.. "No more than 14: the end of the amphioxus Hox cluster.". International journal of biological sciences 1 1 (2005): 19-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-28844487573&partnerID=MN8TOARS.
  180. Santos, M.M.; Castro, L.F.C.; Vieira, M.N.; Micael, J.; Morabito, R.; Massanisso, P.; Reis-Henriques, M.A.. "New insights into the mechanism of imposex induction in the dogwhelk Nucella lapillus". Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 141 1 (2005): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-21844434956&partnerID=MN8TOARS.
    10.1016/j.cca.2005.05.008
  181. Castro, L.F.C.; Santos, M.M.; Reis-Henriques, M.A.. "The genomic environment around the Aromatase gene: Evolutionary insights". BMC Evolutionary Biology 5 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-25444529171&partnerID=MN8TOARS.
    10.1186/1471-2148-5-43
  182. Castro, L.F.C.; Furlong, R.F.; Holland, P.W.H.. "An antecedent of the MHC-linked genomic region in amphioxus". Immunogenetics 55 11 (2004): 782-784. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542359004&partnerID=MN8TOARS.
    10.1007/s00251-004-0642-9
  183. Cabral, H.N.; Castro, F.; Linhares, D.; Alexandrino, P.. "Genetic differentiation of Solea solea (Linnaeus, 1758) and Solea senegalensis Kaup, 1858, (Pisces: Pleuronectiformes) from several estuarine systems of the Portuguese coast,Diferenciacíon genética de Solea solea (Linneus, 1758) y Solea senegalensis Kaup, 1858), (Pisces: Pleuronectiformes) en varios sistemas estuáricos de la costa Portuguesa". Scientia Marina 67 1 (2003): 43-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038814743&partnerID=MN8TOARS.
    10.3989/scimar.2003.67n143
  184. Luke, G.N.; Castro, L.F.C.; McLay, K.; Bird, C.; Coulson, A.; Holland, P.W.H.. "Dispersal of NK homeobox gene clusters in amphioxus and humans". Proceedings of the National Academy of Sciences of the United States of America 100 9 (2003): 5292-5295. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038303006&partnerID=MN8TOARS.
    10.1073/pnas.0836141100
  185. Castro, L.F.C.; Holland, P.W.H.. "Chromosomal mapping of ANTP class homeobox genes in amphioxus: Piecing together ancestral genomes". Evolution and Development 5 5 (2003): 459-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141454675&partnerID=MN8TOARS.
    10.1046/j.1525-142X.2003.03052.x
  186. Castro, L.F.C.; Holland, P.W.H.. "Fluorescent in situ hybridisation to amphioxus chromosomes". Zoological Science 19 12 (2002): 1349-1353. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036991862&partnerID=MN8TOARS.
    10.2108/zsj.19.1349
  187. Castro, F.; Linhares, D.; Alexandrino, P.. "Acid phosphatase polymorphism in European shad (fish: Clupeids)". Biochemical Genetics 37 7-8 (1999): 251-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032705679&partnerID=MN8TOARS.
    10.1023/A:1018746907940
  188. Le Corre, M.; Linhares, D.; Castro, F.; Alexandrino, P.; Sabatié, R.; Bagliniere, J.L.. "Premiers éléments de caractérisation génétique de l'alose du rhône (Alosa fallax rhodanensis roule, 1924)". BFPP - Bulletin Francais de la Peche et de la Protection des Milieux Aquatiques 71 350-51 (1998): 635-645. http://www.scopus.com/inward/record.url?eid=2-s2.0-0010880452&partnerID=MN8TOARS.
    10.1051/kmae:1998031
Capítulo de livro
  1. Fonseca, Elza; Ruivo, Raquel; Miguel M. Santos; C. Castro, L. Filipe; Elza Fonseca; Raquel Ruivo; L. Filipe C. Castro. Autor correspondente: C. Castro, L. Filipe. "1.4. Endocrine Disruption Chemicals and their Mode of Action: the case of Nuclear Receptors and the evolution of the Metazoa". In Environmental Contaminants and Endocrine Health, editado por Oliana Carnevali; Gary Hardiman. Academic Press, 2023.
    No prelo • 10.1016/B978-0-12-824464-7.00016-7
  2. Monroig, O.; Tocher, D.R.; Castro, L.F.C.. "Polyunsaturated Fatty acid biosynthesis and metabolism in fish". 31-60. 2018.
    10.1016/b978-0-12-811230-4.00003-x
  3. Neuparth, T.; Castro, L.F.C.; Santos, M.M.. "Biological effects of organotins in the marine environment". 103-120. 2017.
Livro
  1. Santos, M.M.; Reis-Henriques, M.A.; Castro, L.F.C.. Lipid homeostasis perturbation by organotins: Effects on vertebrates and invertebrates. 2012.
    10.2174/978160805265311201010083
  2. Wilson, J.M.; Castro, L.F.C.. Morphological diversity of the gastrointestinal tract in fishes. 2010.
    10.1016/S1546-5098(10)03001-3
Poster em conferência
  1. SILVA, NÁDIA; C. Castro, L. Filipe; Raquel Ruivo; Valente, Raul. "The hunger hormone in Cetacea: a remarkable story of duplication and loss". Trabalho apresentado em Blue Think Conference, 2023.
  2. Beatriz Santos Silva; Alves, Filipe; Ana Dinis; Rita Ferreira; Correia, Mafalda; Raúl Valente; Ágatha Gil; et al. "Investigation of respiratory prokaryotic communities of free-ranging short-finned pilot whales using non-invasive sampling". Trabalho apresentado em Blue Think Conference 22', 2022.
  3. Raúl Valente; ALVES, LUÍS; Miguel Nabais; Alves, Filipe; Isabel Sousa-Pinto; Ruivo, Raquel; C. Castro, L. Filipe. "Setting the rhythm: how gene loss events shaped marine mammal circadian rhythmicity". Trabalho apresentado em 24th Biennial Conference on the Biology of Marine Mammals, 2022.
  4. Maria Tomasino; Beatriz Santos Silva; Alves, Filipe; Ana Dinis; Rita Ferreira; Correia, Mafalda; Raúl Valente; et al. "Dive into the blow microbiome of free-ranging short-finned pilot whales: protocol optimization and preliminary results". Trabalho apresentado em 24th Biennial Conference on the Biology of Marine Mammals, 2022.
  5. Sousa, João; Degli-Esposti, Davide; Geffard, Olivier; Chaumot, Arnaud; C. Castro, L. Filipe; Miguel M. Santos; Neuparth, Teresa; Ruivo, Raquel 1614-5EAA-2361. "Risk assessment in the Anthropochemical era: A receptor-based tool for the identification of Endocrine Disrupting Chemicals". Trabalho apresentado em 32nd European Society for Comparative Biochemistry and Physiology (ESCPB), 2022.
  6. Biltes,R; Páscoa, Inês; Sousa, João; Vasconcelos, Vitor; C. Castro, L. Filipe; Preto, Marco; Ruivo, R. A.; Cunha, Isabel. "Can Cyanobacteria help on lipid metabolism and inflammatory disorders?". Trabalho apresentado em 12th European Conference on Marine Natural Products Galway, Ireland, 2021.
  7. Biltes, Rita; Páscoa, Inês; Sousa, João; Vasconcelos, Vitor; C. Castro, L. Filipe; Preto, Marco; Ruivo, Raquel; Cunha, I. "CAN CYANOBACTERIA HELP OUT LIPID METABOLISM AND INFLAMMATORY DISORDERS?". Trabalho apresentado em XII European Conference on Marine Natural Products, 2021.
  8. Sousa, João; Neuparth, Teresa; Chaumot, Arnaud; C. Castro, L. Filipe; Geffard, Olivier; Santos, Miguel; Degli-Esposti, Davide; Ruivo, Raquel 1614-5EAA-2361. "Endocrine disrupting chemicals in gammarids: the Ecdysone Receptor as molecular sentinel". Trabalho apresentado em Blue Think Conference, CIIMAR, Matosinhos, Portugal, 2021.
  9. Sousa, João; Neuparth, Teresa; C. Castro, L. Filipe; Santos, Miguel; Ruivo, Raquel 1614-5EAA-2361. "The Amphipod Ecdysone Receptor: In vitro identification of endocrine disrupting chemicals". Trabalho apresentado em IJUP- Encontro de Investigação Jovem, 2021.
  10. Biltes, Rita; Páscoa, Inês; Sousa, João; Lopes-Marques, Mónica; Preto, Marco; Vasconcelos, Vitor; C. Castro, L. Filipe; et al. "A molecular cell-based sensor to detect PPAR ligands - an optimized tool for drug discovery in cyanobacteria". Trabalho apresentado em Blue Think Conference, CIIMAR, Matosinhos, Portugal, 2020.
  11. Alves, Filipe; Dromby, Morgane; Baptista, Vânia; Ferreira, Rita; Correia, Mafalda; Wyen, Mieke; Valente, Raul; et al. "Using RNA/DNA ratios and Carbon/Nitrogen stable isotopes to assess the nutritional condition and trophic ecology of two cetacean species in an oceanic habitat.". Trabalho apresentado em World Marine Mammal Science Conference, 2019.
  12. Páscoa, Inês; Biltes, Rita; Sousa, João; Vasconcelos, Vitor; C. Castro, L. Filipe; Preto, Marco; Lopes-Marques, Mónica; Ruivo, Raquel 1614-5EAA-2361; Cunha, Isabel. "A multiplex vector-based cell sensor for PPARs related drug discovery". Trabalho apresentado em Genomics for a Blue Economy Conference, Stazione Zoologica Anton Dohrn, Napoles, Italy, 2019.
  13. Fonseca, Elza; Ruivo, Raquel; Corado, Francisca; Machado, André; Santos, Miguel; C. Castro, L. Filipe. "Preservation and loss of the Pregnane X Receptor in chondrichthyans sheds light into the early evolution of detoxification mechanisms in gnathostomes.". Trabalho apresentado em 31st ESCPB congress - European Society of Comparative Physiology and Biochemistry, 2018.
  14. Corado, Francisca; Ruivo, Raquel; Machado, André; Fonseca, Elza; Santos, Miguel; C. Castro, L. Filipe. "PPARg evolution in teleosts: gene duplication, retention, and loss.". Trabalho apresentado em 31st ESCPB congress - European Society of Comparative Physiology and Biochemistry, 2018.
  15. Fonseca, Elza; Ruivo, Raquel; Lopes-Marques, Mónica; Fonseca, Miguel; Machado, André; Santos, Miguel; C. Castro, L. Filipe. "The "Neglected": the "insightful" repertoire of nuclear receptors in Protostomes". Trabalho apresentado em 7th meeting of the European Society for Evolutionary Developmental Biology (EED), 2018.
  16. Lopes-Marques, Mónica; CAPITÃO, ANA; Ruivo, Raquel; Fonseca, Elza; Santos, Miguel; C. Castro, L. Filipe. "Structural and Molecular Underpinnings of Variable Obesogen Sensitivity in Vertebrates". Trabalho apresentado em 18º Portugaliae Genetica, 2018.
  17. Brito, Francisca; Sthelio, F.; Peixoto, MJ; Domingues, A.; Damasceno-Oliveira, A.; Gonçalves, José; C. Castro, L. Filipe; Cunha, I.; Ozório, R.O.A.. "Metabolic regulation in meagre, Argyrosomus regius (Asso, 1801): Study of gene-diet interactions on lipid metabolism". Trabalho apresentado em IMMR | International Meeting on Marine Research 2014, 2014.
    10.3389/conf.fmars.2014.02.00014
  18. Cunha, Isabel; Galante-Oliveira, Susana; Rocha, Eduardo; C. Castro, L. Filipe; Galante-Oliveira S,; Resende D,; Castro LFC.; et al. "Effects of treatment with the standard PPAR¿ ligand WY14,643 on juvenile turbot Scophthalmus maximus. II. Gene expression". Trabalho apresentado em Society of Environmental Toxicology and Chemistry (SETAC) Meeting, 2010.
Pré-impressão
  1. Raul Valente; Miguel Cordeiro; Bernardo Pinto; André Machado; Filipe Alves; Isabel Sousa-Pinto; Raquel Ruivo; L. Filipe C. Castro. "Alterations of Pleiotropic Neuropeptide-Receptor gene couples in Cetacea". 2024. https://doi.org/10.1101/2024.02.03.578746.
    10.1101/2024.02.03.578746
  2. André Gomes-dos-Santos; Manuel Lopes-Lima; André M. Machado; Thomas Forest; Guillaume Achaz; Amílcar Teixeira; Vincent Prié; L. Filipe C. Castro; Elsa Froufe. "The Crown Pearl V2: an improved genome assembly of the European freshwater pearl musselMargaritifera margaritifera(Linnaeus, 1758)". 2023. https://doi.org/10.1101/2023.02.11.528107.
    10.1101/2023.02.11.528107
  3. André Gomes-dos-Santos; Nair Vilas-Arrondo; André M. Machado; Esther Román-Marcote; Jose Luís Del Río Iglesias; Francisco Baldó; Montse Pérez; et al. "Rare but not absent: the Inverted Mitogenomes of Deep-Sea Hatchetfish". 2023. https://doi.org/10.1101/2023.06.12.544378.
    10.1101/2023.06.12.544378
Resumo em conferência
  1. Pinto, Rui; Miguel M. Fonseca; Josefin Stiller; Valente, Raul; Ruivo, Raquel; Rute da Fonseca; C. Castro, L. Filipe. "From PseudoChecker2.0 to PseudoViz: a story of gene loss". Trabalho apresentado em SMBE23, Ferrara, 2023.
    Publicado
  2. Fonseca, E; Silva, Beatriz; Gomes-dos-Santos, André; Machado, André; Pinto, Rui; C. Castro, L. Filipe; Froufe, Elsa. "Genomic Adaptations Associated with Climate Change and Biological Changes in the unionid mussel Unio delphinus (Spengler, 1793)". Trabalho apresentado em SMBE23, Ferrara, 2023.
    No prelo
  3. Pinheiro, João; Gomes-dos-Santos, André; C. Castro, L. Filipe; Froufe, Elsa; Fonseca, Elza. "Nuclear receptors and the mussels that "don't get better with butter"". Trabalho apresentado em IJUP 2023, Porto, 2023.
    No prelo
  4. Lago, Íris; Fonseca, Elza; Gasnier, Bruno; C. Castro, L. Filipe; Ruivo, Raquel. "MiT/TFE Family of Transcription Factors in Invertebrates: from nutrient sensing to environmental markers?". Trabalho apresentado em IJUP 2023, Porto, 2023.
    No prelo
  5. Pinto, Bernardo; Malakpourkolbadinezhad, Salman; Cordeiro, Miguel; Machado, André; Ruivo, Raquel; Fonseca, Elza; Andrade, José Pedro; et al. "Sans Glomeruli: the recurrent origin of aglomerular kidneys in teleosts". Trabalho apresentado em IJUP 2023, 2023.
    No prelo
  6. Beatriz Silva; Alves, Filipe; Ana Dinis; Rita Ferreira; Correia, Ana M.; Valente, Raul; Ágatha Gil; et al. "Blow microbiota of free-ranging short-finned pilot whales: Comparison of 16S rRNA primers for studies of blow prokaryotic communities". Trabalho apresentado em 34th Annual Conference of the European Cetacean Society, O'Grove, 2023.
    Aceite para publicação
  7. Valente, Raul; Kang H; Sun S; da Fonseca RR; Correia, Ana M.; Ágatha Gil; Sousa-Pinto, I; et al. "The last piece of the puzzle: a population genomics study in Globicephala macrorhynchus". Trabalho apresentado em 34th Annual Conference of the European Cetacean Society, O'Grove, 2023.
    Aceite para publicação
  8. Bernardo Pinto; Valente, Raul; Salvador-Caramelo, Filipe; Raquel Ruivo; C. Castro, L. Filipe. "Convergent Gene Decay of Skin specific Gene Modules in the Pangolin Ancestor". Trabalho apresentado em Young Sistematists¿ Forum 2022, 2022.
  9. Diogo Oliveira; Valente, Raul; Daniela Soares; Susana Barbosa; Miguel Santos; C. Castro, L. Filipe; Raquel Ruivo. "Massive gene loss and the making of xenobiotic-induced responses in cetacea". Trabalho apresentado em Blue Think Conference 2022, 2022.
  10. Valente, Raul; Bernardo Pinto; Salvador-Caramelo, Filipe; Andre M. Machado; Alves, Filipe; Sousa-Pinto, Isabel; Miguel Cordeiro; Raquel Ruivo; C. Castro, L. Filipe. "Modelling Mammalian behavioural traits: Inactivation of several Neuropeptides and Receptors in Cetacea and other mammals". Trabalho apresentado em Blue Think Conference 2022, 2022.
  11. C. Castro, L. Filipe; Andre M. Machado; Diogo Oliveira; Valente, Raul; et al.. "The Snail, the Shark and the Whale: From Evolution to Endocrine Disruption". Trabalho apresentado em Euro Evo Devo Meeting 2022, 2022.
  12. Sousa, Diogo; Fonseca, Elza; Sousa, João; Ruivo, Raquel; Santos, Miguel; C. Castro, L. Filipe. "Evolution of endocrine systems in Lophotrochozoans". Trabalho apresentado em IJUP 2022, Porto, 2022.
    Publicado
  13. Bernardo Pinto; Valente, Raul; Raquel Ruivo; C. Castro, L. Filipe. "Gene erosion of Sebum-producing genes in Pangolins". Trabalho apresentado em Young Investigation Conference of University of Porto (IJUP), 2022.
  14. Lopes, G; Castro, LFC; Sousa, V; Valente, LMP. "LONG TERM FEEDING OF VEGETABLE OIL BASED DIETS AFFECTS MUSCLE CELLULARITY AND THE EXPRESSION OF GROWTH-RELATED GENES". 2017.
  15. Santo, Miguel; Lyssimachou, Angeliki; Lopes-Marques, Mónica; CAPITÃO, ANA; Fonseca, Elza; Ruivo, Raquel; C. Castro, L. Filipe. "Obesogens: molecular signaling pathways in fish". Trabalho apresentado em XV European Congress of Ichthyology, Porto, 2015.
    Publicado
  16. Goncalves, OM; Fontainhas Fernandes, A; Castro, LC; Smolka, A; Wilson, J. "Gastric proton pump expression in teleost fishes: Nongastric sites of expression in gastric versus agastric fishes". 2008.
    10.1016/j.cbpa.2008.04.225

Outros

Conjunto de dados
  1. Machado, M.M; Sarropolou. E.; C. Castro, L. Filipe; Vasconcelos, Vitor; Cunha, I.. DATASET: An important resource for understanding bio-adhesion mechanisms: Cement gland transcriptomes of two goose barnacles, Pollicipes pollicipes and Lepas anatifera (Cirripedia, Thoracica). https://figshare.com/s/0ea6cbea86bfdd39d7e7.
Outra produção
  1. Uncovering a 500 million year old history and evidence of pseudogenization for TLR15 (vol 13, 1020601, 2022). 2023. Neves, F; Munoz-Merida, A; Machado, AM; Almeida, T; Gaigher, A; Esteves, PJ; Castro, LFC; Verissimo, A.
    10.3389/fimmu.2023.1216338
  2. How genomics can help biodiversity conservation. 2023. Theissinger K.; Fernandes C.; Formenti G.; Bista I.; Berg P.R.; Bleidorn C.; Bombarely A.; et al.
    10.1016/j.tig.2023.01.005
  3. PacBio Hi-Fi genome assembly of the Iberian dolphin freshwater mussel Unio delphinus Spengler, 1793. 2023. Gomes-dos-Santos, A; Lopes-Lima, M; Machado, MA; Teixeira, A; Castro, LFC; Froufe, E; Gomes-dos-Santos André; et al. https://doi.org/10.1101/2023.01.16.524251.
    10.1038/s41597-023-02251-7
  4. A drastic shift in the energetic landscape of toothed whale sperm cells. Current Biology. 2021. Alves, L.Q.; Ruivo, R.; Valente, R.; Fonseca, M.M.; Machado, A.M.; Plön, S.; Monteiro, N.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105608441&partnerID=MN8TOARS.
    10.1101/2021.03.01.432277
  5. A genome assembly of the Atlantic chub mackerel (Scomber colias): A valuable teleost fishing resource. 2021. Machado, A.M.; Gomes-Dos-Santos, A.; Fonseca, M.; da Fonseca, R.R.; Veríssimo, A.; Felício, M.; Capela, R.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85121411422&partnerID=MN8TOARS.
    10.1101/2021.11.19.468211
  6. The male and female gonad transcriptome of the edible sea urchin, Paracentrotus lividus: identification of sex-related and lipid biosynthesis genes. 2021. Machado, A.M.; Fernández-Boo, S.; Nande, M.; Pinto, R.; Costas, B.; Castro, L.F.C.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115589759&partnerID=MN8TOARS.
    10.1101/2021.08.30.458199
  7. Temporal and sex-dependent gene expression patterns in a renal ischemia-reperfusion injury and recovery pig model. 2021. Nemours, S.; Castro, L.; Ribatallada-Soriano, D.; Semidey, M.E.; Aranda, M.; Ferrer, M.; Sanchez, A.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118024335&partnerID=MN8TOARS.
    10.1101/2021.09.01.458480
  8. The Crown Pearl: a draft genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758). 2020. André Gomes-dos-Santos; Manuel Lopes-Lima; André M. Machado; António Marcos Ramos; Ana Usié; Ivan N. Bolotov; Ilya V. Vikhrev; et al. https://doi.org/10.1101/2020.12.06.413450.
    10.1101/2020.12.06.413450
  9. Differential cetacea circadian rhythmicity is associated with the molecular erosion of cortistatin. 2020. Valente, R.; Alves, L.Q.; Nabais, M.; Alves, F.; Sousa-Pinto, I.; Ruivo, R.; Castro, L.F.C.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098910863&partnerID=MN8TOARS.
    10.1101/2020.05.11.087833
  10. The dopamine receptor D5 gene shows signs of independent erosion in Toothed and Baleen whales. 2019. Luís Q. Alves; Juliana Alves; Rodrigo Ribeiro; Raquel Ruivo; L. Filipe C. Castro. https://doi.org/10.1101/556035.
    10.1101/556035
  11. Expansion, retention and loss in the Acyl-CoA Synthetase “Bubblegum” (Acsbg) gene family in vertebrate history. 2018. Mónica Lopes-Marques; André M. Machado; Raquel Ruivo; Elza Fonseca; Estela Carvalho; L. Filipe C. Castro. https://doi.org/10.1101/288530.
    10.1101/288530
  12. A taxonomically-restricted Uric Acid transporter provides insight into antioxidant equilibrium. 2018. Diogo Oliveira; André Machado; Tiago Cardoso; Mónica Lopes-Marques; L. Filipe C. Castro; Raquel Ruivo. https://doi.org/10.1101/287870.
    10.1101/287870
  13. The singularity of Cetacea behaviour parallels the complete inactivation of melatonin gene modules. 2018. Lopes-Marques, M.; Ruivo, R.; Alves, L.Q.; Sousa, N.; Machado, A.M.; Castro, L.F.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85095644533&partnerID=MN8TOARS.
    10.1101/490219
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2019/10/01 - Atual Unravelling the genomic basis of physiological diving adaptations and population structure in Cetacea
Orientador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/09/12 - Atual Inferring phylogeny, demography and adaptive evolution in Margaritiferidae from High-throughput Sequencing data
Coorientador de André Santos
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/09/12 - Atual Genetic diversity within Thymallus: from species delimitation to whole genome sequencing
Coorientador de Giulia Secci
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2016/02/26 - Atual Development of high throughput embryo bioassays as screening tools for the hazard assessment of emerging pollutants
Coorientador de Ricardo Capela
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2015/02/05 - 2020/06/30 Nuclear Receptors in Metazoan lineages: the cross-talk between Evolution and Endocrine Disruption
Orientador de Elza Fonseca
Doutoramento em Biologia (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2017/09/01 - 2020/06/21 From genes to nutrition: lipid metabolism in the Brazilian teleost tambaqui (Colossoma macropomum)
Orientador de Renato Ferraz
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/10/15 - 2019/10/15 PseudoChecker: An integrated online platform for automated gene loss inference in mammals
Orientador de Luís Quádrio Alves
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2014/10/14 - 2018/10/14 Screening obesogens in aquatic model organisms
Orientador de Ana Capitão
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2017/09/13 - 2018/10/13 Ecotoxicology of deep sea environments.
Coorientador de Bárbara Marlene Teixeira Pinheiro
2016/09/07 - 2017/09/07 Obesity and environmental pollutants: a reason for concern?
Coorientador de Melanie Audrey Gomes Barbosa
2013/09/01 - 2017/09/04 The evolution of fatty acid metabolism in chordates
Orientador de Mónica Marques-Lopes
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/08/13 - 2017/08/31 Cobalamin Receptors: Transitions for Novel Functions?
Coorientador de Diogo Oliveira
2012/02 - 2017/02/10 The origin of the vertebrate stomach and the paradox of loss
Coorientador de Odete Gonçalves
PhD (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/01/01 - 2016/06/23 Environmental monitoring and molecular mechanistic insights on pesticides in water and in the bivalve Scrobicularia plana, from Mondego and Tagus estuaries and Ria Formosa Lagoon.
Coorientador de Catarina Cruzeiro
Doutoramento (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/01/01 - 2016/06/21 Impact of endocrine disrupting chemicals in nuclear receptor signaling in marine organisms: invertebrate insight
Coorientador de Ana André
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2018/09/09 - 2018/09/12 Organizer and host of the 31st Congress of the European Comparative Physiology and Biochemistry, Porto (Portugal). (2018/09/09 - 2018/09/12)
Conferência (Coorganizador)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2020/02/16 - 2020/02/16 CONVERSAS COM CIÊNCIA | O MISTERIOSO SONO DOS GOLFINHOS: HISTÓRIAS DE EVOLUÇÃO DEBAIXO DE ÁGUA
Seminário
CONVERSAS COM CIÊNCIA
Fundação Serralves, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2019/02/01 - 2020/02/18 Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (1532-0456) Elsevier

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2018/03/28 - 2018/06/30 Scientific Expert for the National Research Agency (ANR) - France, in the evaluation process of the Generic Call 2018.
Avaliador
Agence nationale de la recherche, França Agence nationale de la recherche

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2019/05/22 O que há de tão especial na pele dos golfinhos e das baleias? Público
2018/10/13 Eis (finalmente) o genoma da sardinha. E em duplicado Público
2018/05/07 Biologia - Corais, lapas e amêijoas também produzem ómega-3 Público
2013/12/25 Como se perde um estômago? Gene a gene, ao longo da evolução Público

Entrevista / Programa (rádio / tv)

Programa Tema
2019/05/21 - 2019/05/21 Mentes que Brilham, Porto Canal Baleias e golfinhos dormem só com metade do cérebro
2018/03/27 - 2018/03/27 90 segundos de ciência Projecto CORAL desenvolve sensores para explorar o mar profundo

Membro de associação

Nome da associação Tipo de participação
2018/08/29 - 2022/08/29 European Society of Comparative Endocrinology Council member
2018 - 2020 European Society of Comparative Physiology and Biochemistry. Co-President