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Liliana Cristina Pereira Montezinho is an Assistant Professor at Vasco da Gama University School, where she teaches in the Integrated Master's Degree in Veterinary Medicine and the Degree in Bioveterinary Sciences. She has a good publication record with 25 articles published in peer-reviewed journals and two book chapters. Additionally, she holds one registered patent. From 2006 to 2014, Liliana worked as a Research Scientist at Lundbeck A/S, a pharmaceutical company in Denmark. During this period, she actively contributed to and led research projects focused on developing new drugs for the treatment of neurological diseases. Between 2014 and 2017, Liliana served as a consultant for "Eurotrials A/S Scientific Consultants," engaging in various medical writing activities. Since 2015, she has been an Assistant Professor at Vasco da Gama University School in Coimbra, responsible for teaching different Biochemistry Curricular Units in the Integrated cycle of studies leading to a Master's degree in Veterinary Medicine and a degree in Bioveterinary Sciences. As a European Commission expert since 2016 (CT-EX2016D288365), Liliana has evaluated a total of 28 projects under The Marie Sklodowska-Curie Actions. At Vasco da Gama University School, she actively participates in multiple committees, including holding key positions such as Vice-President of the Scientific Council, Coordinator of the Skills Accreditation Committee, and Member of the EUVG Ethics Committee. Liliana's professional career spans various areas of fundamental, applied, and clinical research. She has become a member of the Vasco da Gama Research Center (CIVG) and collaborates with the CNC research group, specifically the Mitochondrial Toxicology and Experimental Therapeutics Laboratory at the Center for Neuroscience and Cell Biology. In this role, she contributes as a member to funded research projects in the field of medical sciences.
Identificação

Identificação pessoal

Nome completo
Liliana Cristina Pereira Montezinho

Nomes de citação

  • Montezinho, LP

Identificadores de autor

Ciência ID
DF1F-AC3C-D459
ORCID iD
0000-0002-6877-4286
Formação
Grau Classificação
2001 - 2006
Concluído
Bioquímica (Doutoramento)
Especialização em Biofísica Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Efeitos do lítio nos processos de transdução de sinal acoplados à adenilato ciclase: importância para o tratamento da doença bipolar" (TESE/DISSERTAÇÃO)
Magna Cum Laude
2006
Concluído
Bioquímica (Doutoramento)
Especialização em Especialidade: Biofísica Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Efeitos do Lítio Nos Processos de Transdução de Sinal Acoplados À Adenilato Ciclase. Importância para o Tratamento da Doença Bipolar" (TESE/DISSERTAÇÃO)
1995 - 2000
Concluído
Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Estudos de transporte, ligação e competição do Lítio em células cromafins bovinas" (TESE/DISSERTAÇÃO)
16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2008 - 2014 Investigador principal (carreira) (Investigação) H Lundbeck A/S, Dinamarca
H Lundbeck A/S, Dinamarca
2006 - 2008 Pós-doutorado (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
H Lundbeck A/S, Dinamarca

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2015/02/01 - Atual Professor Auxiliar (Docente Universitário) Escola Universitária Vasco da Gama, Portugal
2014 - 2019 Professor Auxiliar (Docente Universitário) Escola Universitária Vasco da Gama, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2014 - 2019 Conselho científico/técnico-científico ou orgão correspondente Escola Universitária Vasco da Gama, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2014 - 2017 External Consultant CTI Clinical Trial and Consulting Services Lisbon, Portugal
CTI Clinical Trial and Consulting Services Lisbon, Portugal
Projetos

Bolsa

Designação Financiadores
2006 - 2008 Study of the pro-cognitive properties of antidepressants in animal models of depression
SFRH/BPD/18389/2004
Bolseiro de Pós-Doutoramento
H Lundbeck A/S, Dinamarca
Fundação para a Ciência e a Tecnologia
Concluído
2001 - 2005 Effects of lithium on signal transduction processes coupled to adenylate cyclase: importance for the treatment of bipolar disorder
SFRH/BD/3286/2000
Bolseiro de Doutoramento
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2022/01/01 - 2023/12/31 Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07/26 - 2021/07/25 Restoring the Functionality to the Injured Spinal Cord Through the Combinatory Action of Pharmaco-Therapies and Tissue Engineering Strategies
PTDC/CAL-EST/29206/2017
Universidade do Minho, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2000/09/01 - 2001/06/30 Cellular and molecular targets of the therapeutic action of Li+ in bipolar disease
POCTI/36160/BCI/2000
Investigador
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2018/05/01 - 2021/04/30 Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2013/10 - 2015/09 immunotherapy with alpha-synuclein specific antibody
Synuclein Therapeutic Acceleration Program (SynT AP 2013)
Investigador
H Lundbeck A/S, Dinamarca
Michael J Fox Foundation for Parkinson's Research
Concluído
2000/07/01 - 2001/12/31 Cellular and Molecular Targets of the Therapeutic Action of Li+ in Bipolar Disorder
POCTI/1999/BCI/36160
Outra
Produções

Publicações

Artigo em revista
  1. Teresa Cunha-Oliveira; Liliana Montezinho; Rui F. Simões; Marcelo Carvalho; Elisabete Ferreiro; Filomena S. G. Silva. "Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis". Cells (2024): https://doi.org/10.3390/cells13030248.
    10.3390/cells13030248
  2. Sacoor, Carina; Marugg, John D.; Lima, Nuno R.; Empadinhas, Nuno; Montezinho, Liliana. "Gut-Brain Axis Impact on Canine Anxiety Disorders: New Challenges for Behavioral Veterinary Medicine". Veterinary Medicine International 2024 (2024): 1-10. http://dx.doi.org/10.1155/2024/2856759.
    Publicado • 10.1155/2024/2856759
  3. Santos, João Campos; Marques, Carla Cruz; Baptista, Maria Conceição; Pimenta, Jorge; Teixeira, José; Montezinho, Liliana; Cagide, Fernando; et al. "Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production". (2022): http://hdl.handle.net/10316/102837.
    https://doi.org/10.3390/ani12070804
  4. Sacoor, Carina; Barros, Luís Meireles; Montezinho, Liliana. "What are the potential biomarkers that should be considered in diagnosing and managing canine chronic inflammatory enteropathies?". Open Veterinary Journal 10 4 (2021): 412-430. http://dx.doi.org/10.4314/ovj.v10i4.9.
    10.4314/ovj.v10i4.9
  5. Teresa Cunha-Oliveira; Liliana Montezinho; Catarina Mendes; Omidreza Firuzi; Luciano Saso; Paulo J. Oliveira; Filomena S. G. Silva; et al. "Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention". Oxidative Medicine and Cellular Longevity 2020 (2020): 1-29. https://doi.org/10.1155/2020/5021694.
    10.1155/2020/5021694
  6. Grattagliano, Ignazio; Montezinho, Liliana P.; Oliveira, Paulo J.; Frühbeck, Gema; Gómez-Ambrosi, Javier; Montecucco, Fabrizio; Carbone, Federico; et al. "Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease". Biochemical pharmacology (2019): http://hdl.handle.net/10316/95077.
    https://doi.org/10.1016/j.bcp.2018.11.020
  7. Majbour NK; Vaikath NN; van Dijk KD; Ardah MT; Varghese S; Vesterager LB; Montezinho LP; et al. "Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.". (2016): http://europepmc.org/abstract/med/26782965.
    10.1186/s13024-016-0072-9
  8. Thirstrup K; Sotty F; Montezinho LC; Badolo L; Thougaard A; Kristjánsson M; Jensen T; Watson S; Nielsen SM. "Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.". (2015): http://europepmc.org/abstract/med/26731018.
    10.1016/j.phrs.2015.12.028
  9. Heegaard, Niels HH; Tanassi, Julia T; Bech, Sara; Salvesen, Lisette; Jensen, Peter Lüttge; Montezinho, Liliana CP; Winge, Kristian. "Cerebrospinal fluid a-synuclein in the differential diagnosis of parkinsonian syndromes". Future Neurology 9 5 (2014): 525-532. http://dx.doi.org/10.2217/fnl.14.51.
    10.2217/fnl.14.51
  10. Redrobe JP; Jørgensen M; Christoffersen CT; Montezinho LP; Bastlund JF; Carnerup M; Bundgaard C; Lerdrup L; Plath N. "In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.". (2014): http://europepmc.org/abstract/med/24577516.
    10.1007/s00213-014-3492-7
  11. Sørensen G; Husum H; Brennum LT; Bundgaard C; Montezinho LC; Mørk A; Wörtwein G; Woldbye DP. "Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse.". (2014): http://europepmc.org/abstract/med/24314270.
    10.1111/bcpt.12182
  12. Fonseca CP; Fonseca LL; Montezinho LP; Alves PM; Santos H; Castro MM; Geraldes CF. "23Na multiple quantum filtered NMR characterisation of Na+ binding and dynamics in animal cells: a comparative study and effect of Na+/Li + competition.". (2013): http://europepmc.org/abstract/med/23563802.
    10.1007/s00249-013-0899-8
  13. Mørk A; Montezinho LP; Miller S; Trippodi-Murphy C; Plath N; Li Y; Gulinello M; Sanchez C. "Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats.". (2013): http://europepmc.org/abstract/med/23380522.
    10.1016/j.pbb.2013.01.019
  14. Montezinho, LP. "Lu AA21004, a novel multimodal antidepressant with activity exerted through serotonergic targets". Biological Psychiatry 71 8 (2012): 217S-316S. http://dx.doi.org/10.1016/j.biopsych.2012.02.014.
    10.1016/j.biopsych.2012.02.014
  15. Hovelsø N; Sotty F; Montezinho LP; Pinheiro PS; Herrik KF; Mørk A. "Therapeutic potential of metabotropic glutamate receptor modulators.". (2012): http://europepmc.org/abstract/med/22942876.
    10.2174/157015912799362805
  16. Montezinho LP; Miller S; Plath N; Jensen NH; Karlsson JJ; Witten L; Mørk A. "The effects of acute treatment with escitalopram on the different stages of contextual fear conditioning are reversed by atomoxetine.". (2010): http://europepmc.org/abstract/med/20676614.
    10.1007/s00213-010-1917-5
  17. Witten L; Sager T; Thirstrup K; Johansen JL; Larsen DB; Montezinho LP; Mørk A. "HIF prolyl hydroxylase inhibition augments dopamine release in the rat brain in vivo.". (2009): http://europepmc.org/abstract/med/19156859.
    10.1002/jnr.21988
  18. Sotty F; Montezinho LP; Steiniger-Brach B; Nielsen J. "Phosphodiesterase 10A inhibition modulates the sensitivity of the mesolimbic dopaminergic system to D-amphetamine: involvement of the D1-regulated feedback control of midbrain dopamine neurons.". (2009): http://europepmc.org/abstract/med/19236563.
    10.1111/j.1471-4159.2009.06004.x
  19. Sotty F; Damgaard T; Montezinho LP; Mørk A; Olsen CK; Bundgaard C; Husum H. "Antipsychotic-like effect of retigabine [N-(2-Amino-4-(fluorobenzylamino)-phenyl)carbamic acid ester], a KCNQ potassium channel opener, via modulation of mesolimbic dopaminergic neurotransmission.". (2009): http://europepmc.org/abstract/med/19098162.
    10.1124/jpet.108.146944
  20. Montezinho, L.; Miller, S.; Plath, N.; Mørk, A.. "P.2.d.014 Escitalopram modulates fear conditioning in rats". European Neuropsychopharmacology 17 (2007): S369-S370. http://dx.doi.org/10.1016/s0924-977x(07)70543-6.
    10.1016/s0924-977x(07)70543-6
  21. Montezinho, Liliana P; Mørk, Arne; Duarte, Carlos B; Penschuck, Silke; Geraldes, Carlos FGC; Castro, M Margarida CA. "Effects of mood stabilizers on the inhibition of adenylate cyclase via dopamine D2-like receptors". Bipolar Disorders 9 3 (2007): 290-297. http://dx.doi.org/10.1111/j.1399-5618.2007.00354.x.
    10.1111/j.1399-5618.2007.00354.x
  22. Montezinho, Liliana P.; Castro, M. Margarida C. A.; Duarte, Carlos B.; Penschuck, Silke; Geraldes, Carlos F. G. C.; Mørk, Arne; Montezinho LP; et al. "The interaction between dopamine D2-like and beta-adrenergic receptors in the prefrontal cortex is altered by mood-stabilizing agents". (2006): http://hdl.handle.net/10316/8094.
    https://doi.org/10.1111/j.1471-4159.2005.03654.x
  23. Fonseca CP; Jones JG; Carvalho RA; Jeffrey FM; Montezinho LP; Geraldes CF; Castro MM. "Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.". (2005): http://europepmc.org/abstract/med/16095758.
    10.1016/j.neuint.2005.06.005
  24. Montezinho LP; B Duarte C; Fonseca CP; Glinka Y; Layden B; Mota de Freitas D; Geraldes CF; Castro MM. "Intracellular lithium and cyclic AMP levels are mutually regulated in neuronal cells.". (2004): http://europepmc.org/abstract/med/15287898.
    10.1111/j.1471-4159.2004.02551.x
  25. Fonseca CP; Montezinho LP; Nabais C; Tomé AR; Freitas H; Geraldes CF; Castro MM. "Effects of Li+ transport and intracellular binding on Li+/Mg2+ competition in bovine chromaffin cells.". (2004): http://europepmc.org/abstract/med/15110989.
    10.1016/j.bbamcr.2003.12.005
  26. Montezinho LP; Fonseca CP; Geraldes CF; Castro MM. "Quantification and localization of intracellular free mg in bovine chromaffin cells.". (2002): http://europepmc.org/abstract/med/18475427.
    10.1155/MBD.2002.69
  27. Montezinho, Liliana P.; Fonseca, Carla P.; Geraldes, Carlos F. G. C.; Castro, M. Margarida C. A.. "Quantification and Localization of Intracellular Free Mg2+ in Bovine Chromaffin Cells". (2002): http://hdl.handle.net/10316/12770.
    https://doi.org/10.1155/MBD.2002.69
  28. Fonseca CP; Montezinho LP; Baltazar G; Layden B; Freitas DM; Geraldes CF; Castro MM; et al. "Li influx and binding, and li/mg competition in bovine chromaffin cell suspensions as studied by li NMR and fluorescence spectroscopy.". (2000): http://europepmc.org/abstract/med/18475968.
    10.1155/MBD.2000.357
Capítulo de livro
  1. Crans, Debbie C.; Barkley, Noah E.; Montezinho, Liliana; Castro, M. Margarida. "CHAPTER 7. Vanadium Compounds as Enzyme Inhibitors with a Focus on Anticancer Effects". In Metal-based Anticancer Agents, 169-195. Royal Society of Chemistry, 2019.
    10.1039/9781788016452-00169
  2. P., Carla; P., Liliana; C.A. Castro, M. Margarida. "Li+ in Bipolar Disorder – Possible Mechanisms of Its Pharmacological Mode of Action". In Bipolar Disorder - A Portrait of a Complex Mood Disorder. InTech, 2012.
    10.5772/34560
Poster em conferência
  1. Montezinho, LP; J. Santos; C. Marques; M.C. Baptista; J. Pimenta; J. Teixeira; F. Cagide; et al. "Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development". Trabalho apresentado em 55th Annual Scientific Meeting - ESCI Virtual 2021, 2021.
  2. Montezinho, LP. "Effect of a new mitochondriotropic antioxidant on oocyte maturation and embryo production". Trabalho apresentado em The European Federation of Animal Science (EAAP)- Online virtual meeting, 2020.
  3. Montezinho, LP. "Quantification of zonulin plasma levels in felines with inflammatory disease: a pilot study". Trabalho apresentado em XVI Congresso Internacional Veterinário Montenegro, 2020.
  4. Montezinho, LP. "Lu AA21004, a novel multimodal antidepressant". Trabalho apresentado em American Society for Experimental NeuroTherapeutics, 2012.
  5. Montezinho, LP; Bundgaard C; Montezinho LP; Anderson N; Thomsen C; Mørk A. "Selegiline induces a wake promoting effect in rats which is related to formation of its active metabolites". Trabalho apresentado em Society for Neuroscience Meeting, Washington, 2011.
    10.1016/j.pbb.2016.10.003
  6. Montezinho, LP. "Lu AA21004, a novel antidepressant with multimodal activity modulates brain neurotransmitter levels and hippocampal theta oscillations, and exerts procognitive effects in preclinical models". Trabalho apresentado em 24th ECNP Congress, 2011.
  7. Montezinho, LP. "Acute treatment with the selective serotonin reuptake inhibitor escitalopram potentiates memory consolidation in rats". Trabalho apresentado em Society for Neuroscience Meeting, Washington, 2008.
  8. Montezinho, LP. "1-aminoindan, a main metabolite of rasagiline, enhances dopamine release and provides symptomatic benefit in an animal model of Parkinson’s disease". Trabalho apresentado em XVIIth World Congress on Parkinson’s Disease and Related Disorders, 2007.
  9. Montezinho, LP. "Escitalopram modulates fear conditioning in rats". Trabalho apresentado em 20th ECNP Congress, 2007.
  10. Montezinho, LP. "Effects of mood stabilizing drugs on dopamine D2-like and beta-adrenergic receptors present in rat prefrontal cortex". Trabalho apresentado em Satellite Symposium on Lithium, 2005.
  11. Montezinho, LP; Montezinho, L.P.; Duarte, C.B.; Foneeca, C.P.; Geraldes, C.F.G.; Castro, A.. "Intracellular cAMP levels regulate the accumulation of lithium in neuronal cells". Trabalho apresentado em 17th ECNP Congress, 2004.
    10.1016/s0924-977x(04)80188-3
  12. Montezinho, LP. "Studies of lithium effects in neuronal cellular models: towards the understanding of the therapeutic action of this drug". Trabalho apresentado em 39 Congresso Ibérico de Espectroscopia, 2004.
  13. Montezinho, LP. "Li+ influx and binding, and Li+/Mg2+ competition in bovine chromaffin cells as studied by 7Li NMR and fluorescence spectroscopy". Trabalho apresentado em VII Encontro de Usuários de Ressonância Magnética Nuclear, 2001.
  14. Montezinho, LP. "Molecular mechanisms of the therapeutic action of lithium in manic-depression". Trabalho apresentado em 6th FIGIPS Meeting in Inorganic Chemistry, 2001.
Resumo em conferência
  1. Montezinho, LP. "Beneficial effect of mitochondriotropic antioxidants on oocyte maturation and embryo production". Trabalho apresentado em European Society for Clinical Investigation (ESCI), ESCI Virtual Meeting - COVID Edition, 2020.
    Publicado
  2. Montezinho, LP. "Warburg effect in queens with spontaneous mammary tumors". Trabalho apresentado em 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
    Publicado
  3. Montezinho, LP. "Understanding the cell growth profile of lymphoblasts to study as a model to discover the amyotrophic lateral sclerosis disease mechanisms". Trabalho apresentado em 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
Tese / Dissertação
  1. Botelho, Ana Lourenço. "Quantification and categorisation of microplastics in wild and aquaculture fish and in the water of the Aegean Sea". Mestrado, 2021. http://hdl.handle.net/10400.26/38130.
  2. Nunes, Ana Margarida Martins. "Chemical restraint in free-ranging phocid seals with Tiletamine and Zolazepam". Mestrado, 2021. http://hdl.handle.net/10400.26/38086.
  3. Simões, Andreia Inês Amado. "Abordagem clínica à Diabetes Insipidus em cães e gatos". Mestrado, 2021. http://hdl.handle.net/10400.26/38133.
  4. Bastos, Nádia Filipa Fernandes. "Discinesia paroxística em cães". Mestrado, 2021. http://hdl.handle.net/10400.26/38170.
  5. Santos, João Pedro Campos dos. "Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development". Mestrado, 2020. http://hdl.handle.net/10400.26/34026.
  6. Sacoor, Carina. "What potential biomarkers should be considered in diagnosing and managing canine chronic inflammatory enteropathies?". Mestrado, 2019. http://hdl.handle.net/10400.26/29775.
  7. Almeida, Pedro Manuel Oliveira. "Orthopedic shoeing in equines". Mestrado, 2018. http://hdl.handle.net/10400.26/24491.
  8. Barros, Ana Carolina Fernandes. "Central and peripheral vestibular syndrome in cats and dogs". Mestrado, 2017. http://hdl.handle.net/10400.26/19010.
  9. Miranda, Ana Margarida Cabral Carvalho. "Leptospirosis in dogs: a retrospective study of 9 cases in coimbra". Mestrado, 2015. http://hdl.handle.net/10400.26/16847.
  10. Montezinho, Liliana Cristina Pereira. "Efeitos do lítio nos processos de transdução de sinal acoplados à adenilato ciclase : importância para o tratamento da doença bipolar". Doutoramento, 2006. http://hdl.handle.net/10316/1601.
  11. Montezinho, LP. "Lithium transport, binding and competition studies in bovine chromaffin cells". Licenciatura, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2001.

Propriedade Intelectual

Patente
  1. Montezinho, Liliana; Montezinho, LP. 2017. "Agents, Uses and Methods for the Treatment of Synucleinopathy".
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2014 Detection of different species of a-synuclein in plasma, extracellular fluid, CSF and brain in transgenic animal models for PD Keystone conference
(Estados Unidos)
2012 Preclinical effects of Lu AA21004, a novel multimodal antidepressant 25th ECNP Congress
(Áustria)
2012 The novel antidepressant vortioxetine (Lu AA21004): implications of its multimodal mechanism of action in preclinical functional and behavioral models Serotonin Club meeting
2012 Lu AA21004, a multimodal antidepressant, is active in a fluoxetine-insensitive rat model of depression and enhances cognitive function in rats 165th Annual Meeting of the American Psychiatric Association
2005 Li+ effects on the tricarboxylic acid cycle flux in the human neuroblastoma SHSY5Y cell line: a 13C NMR isotopomer analysis Satellite Symposium on Lithium
2004 Spectroscopic studies of lithium effects on neuronal cellular models and on brain cell metabolism Congresso Luso- Espanhol de Biofísica

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2019/09/01 - 2020/07/31 Impacts of a novel mitochondrial-directed antioxidant on bovine sperm function and in vitro embryo development
Orientador
2018/09/03 - 2019/07/19 What potential biomarkers should be considered in diagnosing and managing canine chronic inflammatory enteropathies?
Orientador
Escola Universitária Vasco da Gama, Portugal
2019 - 2019 Avaliação da zonulina plasmática como potencial biomarcador de patologia inflamatória em Felídeos
Orientador
Medicina Veterinária (Outra)
Escola Universitária Vasco da Gama, Portugal
2018 - 2019 What potential biomarkers should be considered in diagnosing and managing canine chronic inflammatory enteropathies?
Orientador
Medicina Veterinária (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2017 - 2018 Ferração ortopédica em equinos
Orientador
Medicina Veterinária (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2016 - 2017 Síndrome Vestibular Central e Periférica em Cães e Gatos
Orientador
Medicina Veterinária (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2015 - 2015 Leptospirosis in dogs: a retrospective study of 9 cases in Coimbra
Orientador
Medicina Veterinária
Escola Universitária Vasco da Gama, Portugal
2014 - 2015 Interplay between a-synuclein and neuroinflammation for the neurogenesis process and cognition in mice
Orientador
H Lundbeck A/S, Dinamarca
2009 - 2009 Lipopolysaccharide-induced cytokine production in the brain and plasma
Orientador
H Lundbeck A/S, Dinamarca

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2020/07/23 Implementation of an On Farm Culture system in dairy cattle farms in Terceira Island - preliminary results
Presidente do júri
Margarida Mendes Santos Cascão (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2020/07/22 Proximal desmite of the suspensory billet ligament
Presidente do júri
Pedro Alves Neto (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2020/07/21 Septic peritonitis in cats and dogs: A retrospective study
Presidente do júri
Diana Maria Gonçalves de Oliveira S. António (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2020/07/15 Microsurgery teaching methods in Veterinary Medicine
Presidente do júri
Francisco Miguel Costa Cunha Batalha (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2020/06/05 Observation of Wasting Syndrome and diagnosis of Lentivirosis in Small Ruminants - What relationship?
Presidente do júri
Diana Margarida da Silva Valente (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2020/04/15 Cryptosporidiosis in Cattle - Bibliographic Review
Presidente do júri
Pedro João Batista Cairrão (Mestrado)
2019/10/08 Biological and Therapeutic Properties of Honey in the Treatment of Wounds
Arguente principal
Ivan Gonçalves dos Santos (Mestrado)
2019/07/24 Feline psychogenic alopecia
Presidente do júri
Ana Sofia da Silva Andrade (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/07/17 Canine dilated cardiomyopathy, from etiology to therapeutics - what's new?
Presidente do júri
Mariana Gusmão Pinheiro Magano Canha (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/07/17 Primary corneal endotelial degeneration in dogs?
Presidente do júri
Rita Cacho Miranda (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/07/11 Canine mastocytoma: main therapeutic approaches
Presidente do júri
Ana Carina Pereira da Silva (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/07/11 The role of flow cytometry in the assessment of minimal residual disease in dogs with diffuse large cell B lymphoma.
Presidente do júri
Marta Filipa Pimenta Rainho Monteiro (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/07/09 Exotic human-animal cohabitation: addressing this growing interest
Presidente do júri
Mariana Ribeiro da Fonseca (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2019/06/07 Causes of refuse in dairy farms: Literature review
Presidente do júri
Maria de Fátima dos Santos Martins (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2018/07/05 Warburg effect in queens with mammary tumors
Presidente do júri
Melissa Isabelle Martinho de Almeida (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2018/06/13 Prospective and retrospective study of breast tumors in cats
Presidente do júri
Filipa Alexandra Brízido Silva Fernandes (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2018/06/07 Acute phase proteins in queens with pyometra – sérum amyloid alfa .
Presidente do júri
Telma Adriana Ferreira Santos (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2017/07/18 Feline hypertrophic cardiomyopathy: literature review
Presidente do júri
António Manuel Graça Matos Pereira (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2017/07/18 Main cardiac changes found in pre-anesthetic evaluations in dogs
Presidente do júri
Rosa Alexandra Oliveira Henriques Roma (Mestrado)
Escola Universitária Vasco da Gama, Portugal
2016/07/13 Retrospective Study of Leptospirosis in the Baixo Vouga Region between 2011 and 2015
Presidente do júri
João Pedro Gonçalo da Cruz (Mestrado)
Escola Universitária Vasco da Gama, Portugal

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2016 - Atual Evaluation of 28 Marie Sklodowska Curie Individual Fellowships. Expert number CT-EX2016D288365.
Avaliador
European Commission, Bélgica European Commission

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2014 - 2017 Realization of different Medical writing ativities CTI Clinical Trial and Consulting Services Lisbon, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2017 - Atual Coordinator of the first year in the integrated Master in Veterinary Medicine taught in French
Coordenador
Escola Universitária Vasco da Gama, Portugal
2021/02 - 2025 Vice-President of the Scientific Council - EUVG
Presidente / Vice-presidente
Escola Universitária Vasco da Gama, Portugal
2018/07 - 2021/01 President of the Scientific Council - EUVG
Presidente / Vice-presidente
Escola Universitária Vasco da Gama, Portugal

Tutoria

Tópico Nome do aluno
2021/02/01 - 2021/02/28 Integrated Veterinary Practice (internship) Élise Michèle Francine Poret
2021/02/01 - 2021/02/28 Integrated Veterinary Practice (internship) Emeric Stéphane Nicolas Gerbaud
2021/02/01 - 2021/02/28 Integrated Veterinary Practice (internship) Helene Jeanne Yvonne Le Cavorzin
2021/02/01 - 2021/02/28 Integrated Veterinary Practice (internship) Inaia Marie Bertrand
2021/02/01 - 2021/02/28 Integrated Veterinary Practice (internship) Tiên San Lya Sellin
2020/02/28 - 2020/02/28 Integrated Veterinary Practice (internship) Léa Villemagne
2020/02/03 - 2020/02/28 Integrated Veterinary Practice (internship) Léa Godard
2020/02/03 - 2020/02/28 Integrated Veterinary Practice (internship) Léa Mann
2020/02/03 - 2020/02/28 Integrated Veterinary Practice (internship) Luann Blanquet
2020/02/03 - 2020/02/28 Integrated Veterinary Practice (internship) Tânia Monteiro
2019/02/01 - 2019/02/28 Integrated Veterinary Practice (internship) Rosalie Violette Marie Menard
2019/02/01 - 2019/02/28 Integrated Veterinary Practice (internship) Diogo Manuel Francisco Manso
2019/02/01 - 2019/02/28 Integrated Veterinary Practice (internship) Sabrina Khedidja Rabia Kidad-Falhi
2019/02/01 - 2019/02/28 Integrated Veterinary Practice (internship) Sandra Gonçalves
2019/02/01 - 2019/02/28 Integrated Veterinary Practice (internship) Anaelle Marquier
2018/02/01 - 2018/02/28 Integrated Veterinary Practice (internship) Margaux Louise Bolzer
2018/02/01 - 2018/02/28 Integrated Veterinary Practice (internship) Mathilde Nathalie Élisabeth Guillot
2018/02/01 - 2018/02/28 Integrated Veterinary Practice (internship) Melanie dos Santos
2018/02/01 - 2018/02/28 Integrated Veterinary Practice (internship) Olivier David Gérard San German
2017/02/01 - 2017/02/28 Integrated Veterinary Practice (internship) João Miguel Fonseca Marques Pena Dias
2017/02/01 - 2017/02/28 Integrated Veterinary Practice (internship) Luís Nuno Moreirão Cerca Monteiro Oliveira
2017/02/01 - 2017/02/28 Integrated Veterinary Practice (internship) Mafalda Inês Jardim Fernandes
2017/02/01 - 2017/02/28 Integrated Veterinary Practice (internship) Manuel Francisco Cortez Camões
2017/02/01 - 2017/02/01 Integrated Veterinary Practice (internship) Mafalda Inês Jardim Fernandes
2016/02/01 - 2016/02/29 Integrated Veterinary Practice (internship) Anthony Leal
2016/02/01 - 2016/02/28 Integrated Veterinary Practice (internship) Catherine Castel
2016/02/01 - 2016/02/28 Integrated Veterinary Practice (internship) Cindy Lucas
2016/02/01 - 2016/02/28 Integrated Veterinary Practice (internship) Diana Valente
2016/02/01 - 2016/02/28 Integrated Veterinary Practice (internship) Dulce Vieira