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I took my BSc degree in Biochemistry and Food Chemistry in 2008, and my MSc in Organic Chemistry and Natural Products in 2009, both at University of Aveiro (UA). In 2010, I was awarded with a research grant that allowed me to continue my investigation on synthesis and preparation of new flavonoids derivatives at the Professor Artur Silva Group. Later, I was awarded with a PhD fellowship in chemistry by FCT where I worked on Synthesis and transformation of chromones and 4-quinolones. I synthesized around 170 nitrogen and oxygen derivatives and structurally characterized mainly by Proton and Carbon Nuclear Magnetic Resonance (1H and 13C NMR) and Mass spectroscopy (MS). My PhD thesis was distinguished by the honorable mention in Portuguese Award for best PhD Thesis in Organic Chemistry 2017. In September 2016, I started a research fellow for three months, that consisted in synthesis and chemical characterization of pyrazoles, bis-pyrazoles and 1,2-di-hydropyridines. Posteriorly, I worked on DRUGORGINORG project where my investigation focused on evaluation of anticancer effects of organic compounds. In this project I worked on biological science, more precisely in anticancer evaluation of synthetic compounds. I worked at the Institute of Biomedicine (iBiMED) on cell culture and was responsible for the in vitro testing of many compounds (around 70) in 2 breast cancer cell lines (MDA-MB231 and T47-D) and prostate cancer cell line (PC3). I acquired skills and knowledge in cytotoxicity assays, cycle analysis, flow cytometry, immunohistochemistry cells maintenance. This period was very rich and fascinating for me. Between December 2018-Jule 2022, I was researcher at Compass Research Group where I developed investigation on SUPRASORT and COP2P projects. I worked on chemical functionalization and structural characterization of polymers (laminarin, chitosan, hyaluronic acid, peptides, collagen) and DNA nucleobases to be used in production biomaterials for biomedical applications. Once structurally modified these molecules are used in production of biomaterials (hydrogels, membranes) using different conditions like light (photo-crosslinking), temperature or pH. Different techniques are used for structural characterization such as RMN, FTIR, UV-Vis, SEM as well as their mechanical and chemical properties using equipment like Instron and Rheometer (viscosity, young's modulus) and swelling behavior. In February 2023, I integrated G-Cork project as researcher, I developed quartz crystal microbalance (QCM) sensors for volatile compounds detection in cork (project with Amorin Cork as partner). Since April 2024 I was researcher at SPECKO group in the PANACEA project. My duties focus on science management, coordinate students/research exchange, scientific events organization. I do also develop some management work as CO-PI of SUPRASORT project. The research I conducted during my PhD, along with the years leading up to it, allowed me to deepen and strengthen my expertise in organic chemistry, materials science, cell manipulation and biological screening, sensing and science management. I do also developed my skills in problem-solving, team works, communication and critical thinking. It also helped me grow up as a versatile chemist and professional. During my scientific career I had two period of scientific interruption due to maternity (2015 and 2020) and employment. Both interruptions had great impact in scientific and pedagogic career (number, planning and quality). I mentoring students and researchers, co-supervised BSc and 1 MSc students, lectured on experimental classes of Organic-Physical Chemistry and Bioorganic at Department of Chemistry-UA and was jury of academic degree (Master thesis, seminar and BSc projects). Since 2015, I published 15 scientific papers, 2 Portuguese patent (005/2024 and 240/2024), 3 book chapter, 3 thesis, 10 oral/poster communications, 2 magazine and newsletter papers. I organize scientific events and revise papers.
Identificação

Identificação pessoal

Nome completo
Djenisa Helene Ascenção Rocha

Nomes de citação

  • Rocha, Djenisa H. A.

Identificadores de autor

Ciência ID
1B1F-0F26-5BF4
ORCID iD
0000-0002-3508-9135
Researcher Id
7746-2015
Scopus Author Id
55026027700

Endereços de correio eletrónico

  • djenisa@ua.pt (Profissional)
  • djenisarocha@gmail.com (Pessoal)

Moradas

  • Universidade de Aveiro - Departamento de Química - Campus Universitário de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Química - Química Orgânica
  • Ciências Exatas - Química - Ciência de Polímeros
  • Ciências da Engenharia e Tecnologias - Engenharia Médica
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências da Engenharia e Tecnologias - Engenharia do Ambiente - Controle Remoto

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Crioulo e pídgin, baseada em Português (Outras) (Idioma materno)
Português Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2024/10 - 2024/11
Concluído
English course (B2) (Outros)
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2024/07/09 - 2024/07/30
Concluído
Project Management (Outros)
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2023/12 - 2024/02
Concluído
Quality Management - Basic Concepts (Outros)
Instituto do Emprego e Formação Profissional, Portugal
2022/11 - 2023/02
Concluído
Internacionalization - Fundamentals (Outros)
Instituto do Emprego e Formação Profissional, Portugal
2015/03/26
Concluído
Doctoral program in Chemistry (Doutoramento)
Universidade de Aveiro, Portugal
""Estudos de síntese e transformação de cromonas e 4-quinolonas" Studies of the synthesis and transformation of chromones and 4-quinolones" (TESE/DISSERTAÇÃO)
Aprovaded
2009
Concluído
Master in Organic Chemistry and Natural Products (Mestrado)
Universidade de Aveiro, Portugal
""Estudos da reação de Heck de 3-bromoflavonas com estirenos" Studies of Heck reaction of 3-bromoflavones with styrenes" (TESE/DISSERTAÇÃO)
15
2008
Concluído
Biochemistry and Food Chemistry (Licenciatura)
Universidade de Aveiro, Portugal
""Síntese de novos compostos com potencial antioxidante" Synthesis of new compounds as potential antioxidant" (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/04/01 - Atual Investigador Contratado (Investigação) Universidade de Aveiro CICECO, Portugal
2023/02/20 - 2023/06/30 Investigador Contratado (Investigação) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro, Portugal
2018/12/01 - 2022/07/25 Investigador Contratado (Investigação) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Universidade de Aveiro, Portugal
2017/01/01 - 2018/11/30 Investigador (Investigação) Universidade de Aveiro Departamento de Química, Portugal
2016/09/16 - 2016/12/31 Investigador (Investigação) Universidade de Aveiro Departamento de Química, Portugal
2011/04/01 - 2015/03/31 Investigador (Investigação) Universidade de Aveiro Departamento de Química, Portugal
2010/02/02 - 2011/03/31 Investigador (Investigação) Universidade de Aveiro Departamento de Química, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2020/05 - 2020/12 Maternity leave Universidade de Aveiro, Portugal
Projetos

Bolsa

Designação Financiadores
2017/01/01 - 2018/11/30 DRUGORGINORG "Organic-Inorganic Chemotypes as Anticancer and Anti-tumor Drugs"
PT-DZ/0005/2015 - DRUGORGINORG
Bolseiro de Investigação
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/09/16 - 2016/12/31 Synthesis of pyrazoles, bis-pyrazoles 1,2-di-hydropyridines
UID/QUI/00062/2013
Bolseiro de Investigação
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2011/04/01 - 2015/03/31 Synthesis studies and transformation of chromones and 4-quinolones
-
Bolseiro de Doutoramento
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/02/02 - 2011/03/31 Studies of synthesis and processing of new type of flavonoids compounds
-
Bolseiro de Investigação
Universidade de Aveiro Departamento de Química, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares
Concluído

Projeto

Designação Financiadores
2024/04/01 - Atual A Pan-European Solid-State NMR Infrastructure for Chemistry-Enabling Access -PANACEA
101008500
Investigador
Universidade de Aveiro, Portugal
Horizon Europe Excellent Science
Em curso
2023/02/20 - 2023/06/30 Development of monitoring tools for cork volatile compounds (GCork). Co-promotion I&D Amorim
POCl-01-0247-FEDER-070302
Investigador
Universidade de Aveiro CICECO, Portugal
Concluído
2021/10/01 - 2022/07/25 Efficient methodologies for the conjugation of natural polysaccharides with peptides to obtain multifunctional membranes for periodontal regeneration.
COP2P (projeto nº 030771)
Investigador
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/12/01 - 2021/09/30 DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications (Suprasort)
PTDC/QUI-OUT/30658/2017
Investigador
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2021/01/01 - 2022/07/25 DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications (SUPRASORT))
PTDC/QUI-OUT/30658/2017
Co- Principal investigator (Co-PI)
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2022 - 2022 Nanocomposite light-responsive inks for healthcare 3D printing
-
Co-Investigador Responsável (Co-IR)
Não financiado
2022 - 2022 Supramolecular Design of Chemically Programmable and Dynamic Bioactive Self-assembling Multicomponent Biomaterials for Bone Tissue Regeneration
-
Team Member
Não financiado
2020 - 2020 Functionalization of natural polysaccharides with smart molecules mimicking the extracellular matrix
-
Investigador responsável
Não financiado
2019 - 2019 Cape Verde plants: BIOdiversity, ethanopharmacology and PHYTochemical profile
-
Team Member
Não financiado
2017 - 2017 Valorization of the native flora of Baixo Vouga Lagunar: Plants with medicinal properties
-
Investigador responsável
Não financiado
Produções

Publicações

Artigo em boletim informativo
  1. Rocha, Djenisa H. A.. "Synthesis of Benzophenones and in vitro Evaluation of Their Anticancer Potential in Breast and Prostate Cancer Cells", Associação Portuguesa de Investigação em Cancro (ASPIC), 2019, https://www.aspic.pt/pt-pt/node/6827#.YBQhFOj7RPZ.
Artigo em conferência
  1. Rocha, Djenisa H. A.; Leal, Stephanie B.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "New syntheses of potential biologically active xanthones and benzoxanthones". 2013.
Artigo em revista
  1. Liza Saher; Fátima L. Monteiro; Djenisa H. A. Rocha; Hélio M. T. Albuquerque; Artur M. S. Silva; Luisa Helguero. "Selective Induction of DNA Damage and Cell Cycle Arrest Mediated by Chromone-Triazole Dyads Derivatives: Effects on Breast and Prostate Cancer Cells". Chemistry & Biodiversity (2023): http://dx.doi.org/10.1002/cbdv.202300251.
    10.1002/cbdv.202300251
  2. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits". Marine Drugs 20 12 (2022): 789. http://dx.doi.org/10.3390/md20120789.
    Publicado • 10.3390/md20120789
  3. Rocha, Djenisa H. A.; Carmen M. Machado; Vera Sousa; Cristiana F. V. Sousa; Vera L. M. Silva; Artur M. S. Silva; João Borges; João F. Mano. "Customizable and Regioselective One-Pot N-H Functionalization of DNA Nucleobases to Create a Library of Nucleobase Derivatives for Biomedical Applications". European Journal of Organic Chemistry 2021 31 (2021): 4423-4433. https://doi.org/10.1002/ejoc.202100786.
    10.1002/ejoc.202100786
  4. Naouri, Abdelkader; Djemoui, Amar; Ouahrani, Mouhamad Ridha; Lahrech, Mokhtar Boualem; Lemouari, Najet; Rocha, Djenisa H.A.; Albuquerque, Hélio; et al. "Multicomponent and 1,3-dipolar cycloaddition synthesis of triazole- and isoxazole-acridinedione/xanthenedione heterocyclic hybrids: Cytotoxic effects on human cancer cells". Journal of Molecular Structure 1217 (2020): 128325. http://dx.doi.org/10.1016/j.molstruc.2020.128325.
    10.1016/j.molstruc.2020.128325
  5. Rocha, Djenisa H. A.; Batista, Vasco F.; Balsa, Emanuel J. F.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Chromene- and Quinoline-3-Carbaldehydes: Useful Intermediates in the Synthesis of Heterocyclic Scaffolds". Molecules 25 17 (2020): 3791. http://dx.doi.org/10.3390/molecules25173791.
    10.3390/molecules25173791
  6. Djemoui, Amar; Naouri, Abdelkader; Ouahrani, Mohammed Ridha; Djemoui, Djamila; Lahcene, Souli; Lahrech, Mokhtar Boualem; Boukenna, Leila; et al. "A step-by-step synthesis of triazole-benzimidazole-chalcone hybrids: Anticancer activity in human cells+". Journal of Molecular Structure 1204 (2020): 127487. http://dx.doi.org/10.1016/j.molstruc.2019.127487.
    10.1016/j.molstruc.2019.127487
  7. Rocha, Djenisa H. A.; Vaz, Patrícia A. A. M.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Synthesis Chalones and Their Isomerization into Flavanones and Azaflavanones". Methods and Protocols 2 3 (2019): 70. http://dx.doi.org/10.3390/mps2030070.
    10.3390/mps2030070
  8. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Synthesis of 4,5-disubstituted-1H-1,2,3-triazoles". Monatshefte für Chemie - Chemical Monthly (2019): http://dx.doi.org/10.1007/s00706-019-02463-x.
    10.1007/s00706-019-02463-x
  9. Saidi, Lydia; Rocha, Djenisa H. A.; Talhi, Oualid; Bentarzi, Yamina; Nedjar-Kolli, Bellara; Bachari, Khaldoun; Almeida Paz, Filipe A.; Helguero, Luisa A.; Silva, Artur M. S.. "Synthesis of Benzophenones and in vitro Evaluation of Their Anticancer Potential in Breast and Prostate Cancer Cells". ChemMedChem 14 10 (2019): 1041-1048. http://dx.doi.org/10.1002/cmdc.201900127.
    10.1002/cmdc.201900127
  10. Rocha, Djenisa H.A.; Pinto, Diana C. G. A.; Seca, Ana M. L.. "Seaweed Secondary Metabolites In Vitro and In Vivo Anticancer Activity". Marine Drugs 16 11 (2018): 410. http://dx.doi.org/10.3390/md16110410.
    10.3390/md16110410
  11. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Applications of the Wittig Reaction on the Synthesis of Natural and Natural-Analogue Heterocyclic Compounds". European Journal of Organic Chemistry 2018 20-21 (2018): 2443-2457. http://dx.doi.org/10.1002/ejoc.201800523.
    10.1002/ejoc.201800523
  12. Silva, Eduarda; Rocha, Djenisa; Silva, Artur. "Diels–Alder Reactions of 1,2-Dihydropyridines: An Efficient Tool for the Synthesis of Isoquinuclidines". Synthesis 50 12 (2018): 2432-2432. http://dx.doi.org/10.1055/s-0036-1589536.
    10.1055/s-0036-1589536
  13. Varandas, Pedro; Rocha, Djenisa H. A.; Silva, Eduarda M. P.; Silva, Artur M.S.; Paz, Filipe. "One-Pot Synthesis of Isoquinuclidines via 2,6-Diaryl-1,2-dihydropyridines using (E,E)-Cinnamylideneacetophenones as Templates". Synthesis 50 10 (2018): 1965-1972. http://dx.doi.org/10.1055/s-0036-1591767.
    10.1055/s-0036-1591767
  14. Silva, E.M.P.; Silva, A.M.S.; Rocha, Djenisa H. A.. "Diels-Alder Reactions of 1,2-Dihydropyridines: An Efficient Tool for the Synthesis of Isoquinuclidines". Synthesis (Germany) 50 9 (2018): 1773-1782. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045152753&partnerID=MN8TOARS.
    10.1055/s-0037-1609418
  15. Talhi, Oualid; Silva, Artur M.S.; Sousa, Joana L. C.; Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Almeida Paz, Filipe; Bachari, Khaldoun; Kirsch, Gilbert. "One-Pot Synthesis of Novel Highly Functionalized Furan-Based Polyphenolics". Synlett 26 19 (2015): 2724-2729. http://dx.doi.org/10.1055/s-0035-1560580.
    10.1055/s-0035-1560580
  16. Rocha, Djenisa H.A.; Pinto, Diana C.G.A.; Silva, Artur M.S.. "Synthesis and cyclisation studies of ( E )-2-aryl-1-methyl-3-styrylquinolin-4(1 H )-ones". Tetrahedron 71 40 (2015): 7717-7721. http://dx.doi.org/10.1016/j.tet.2015.07.058.
    10.1016/j.tet.2015.07.058
  17. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Seixas, Raquel S. G. R.; Silva, Artur M. S.. "3-Methylflavones characterization revisited: complete assignment of1H and13C NMR data". Magnetic Resonance in Chemistry 52 1-2 (2013): 47-50. http://dx.doi.org/10.1002/mrc.4026.
    10.1002/mrc.4026
  18. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "One-Pot Synthesis of 3-Methylflavones and Their Transformation into (E)-3-Styrylflavones via Wittig Reactions". Synlett 24 20 (2013): 2683-2686. http://dx.doi.org/10.1055/s-0033-1340013.
    10.1055/s-0033-1340013
  19. Rocha, Djenisa; Pinto, Diana C.G.A.; Silva, Artur M.S.; Patonay, Tamás; Cavaleiro, José. "A New Synthesis of 5-Arylbenzo[c]xanthones from Photoinduced Electrocyclisation and Oxidation of (E)-3-Styrylflavones". Synlett 23 04 (2012): 559-564. http://dx.doi.org/10.1055/s-0031-1290355.
    10.1055/s-0031-1290355
  20. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M. S.; Cavaleiro, Jose A. S.; Vaz, Patrícia A. A. M.. "New Syntheses of 3-Aroylflavone Derivatives; Knoevenagel Condensation and Oxidation versus One-Pot Synthesis". Synlett 16 (2012): 2353-2356. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309164100009&KeyUID=WOS:000309164100009.
    10.1055/s-0032-1317159
Artigo em revista (magazine)
  1. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "Estudos de síntese e transformação de cromonas e 4-quinolonas", Química- Boletim da SPQ, 2018, https://www.spq.pt/magazines/BSPQuimica/684.
Capítulo de livro
  1. Rocha, Djenisa; Mano, João F.. "Methacrylated Natural Macromolecules as Precursors of Hydrogels for Biomedical Application". In Synthesis and Applications in Chemistry and Materials, editado por Armando J. L. Pombeiro; Mahmudov, Kamran; M. Fátima C. Guedes da Silva. World Scientific, 2024.
    Publicado
  2. Silva, V. L. M.; Pinto, D. C. G. A.; dos Santos, C. M. M.; Rocha, D. H. A.. "15.4.5 Quinolinones and Related Systems (Update 2022)". In Knowledge Updates 2022/3, 182-442. Georg Thieme Verlag KG, 2022.
    Publicado • 10.1055/sos-sd-115-01218
  3. Rodrigues, J. M. M.; Castanheira, E. J.; Costa, D. C. S.; Rocha, D. H. A.; Borges, J.; Mano, J. F.. "Chapter 8. Extending the Functionality of Marine-origin Polysaccharides Through Chemical Modification for Biomedical Applications". In Soft Matter for Biomedical Applications, 180-204. Royal Society of Chemistry, 2021.
    Publicado • 10.1039/9781839161124-00180
Poster em conferência
  1. Vera Sousa; C.M. Machado; Cristiana F.V. Sousa; Djenisa H. A. Rocha; Vera L.M. Silva; Artur M. S. Silva; João Borges; João F. Mano. "Regioselective functionalization of DNA nucleobases towards a library of nucleobase derivatives for biomedicine". Trabalho apresentado em Jornadas CICECO, 2021.
  2. Rocha, Djenisa H. A.; Saher, Liza; Talhi, Oualid; Djemoui, Amar; Naouri, Abdelkader; Quahrani, M. R.; Djemoui, Djamila; et al. "Synthesis and anticancer activity of triazole-benzimidazolechalcone hybrids (PC90)". Trabalho apresentado em 13th National Organic Chemistry Meeting 6th National Medicinal Chemistry Meeting, 2020.
  3. Rocha, Djenisa H. A.; Machado, C. M; Silva, Vera L. M.; Silva, Artur M. S.; Borges, João; Mano, João F.. "Extending the functionality of nucleobases through regioselective N-derivatization". Trabalho apresentado em XXVI SPQ National Meeting, 2019.
  4. Rocha, Djenisa H.A.; Balsa, Emanuel J. F.; Pinto, Diana C.G.A.. "Synthesis of benzopyran-indole dyads with potential cannabinoid activity (HC31)". Trabalho apresentado em 15th National Meeting of Portuguese Society of Chemistry, 2017.
  5. Rocha, Djenisa H. A.; Saidi, Lydia; Talhi, Oualid; Nedjar-Kolli, B.; Bentarzi, Y.; Mendes, Ricardo F.; Paz, Filipe A.A.; et al. "Synthesis of benzophenone derivatives by the reaction of nitromethane with (E)-3-[3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]-4H-chromen-4-ones (HC65)". Trabalho apresentado em 15th National Meeting of Portuguese Society of Chemistry, 2017.
  6. Rocha, Djenisa H. A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "Strategies towards the synthesis of new (E)-2-aryl-3-styryl-4H-chromen-4-ones and (E)-1-methyl-2-aryl-3-styrylquinolin-4(1H)-ones (P1.77)". Trabalho apresentado em 15th Tetrahedron Symposium – Challenges in Bioorganic and Organic Medicinal Chemistry, 2014.
  7. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.. "Wittig and Heck reaction: two diferent strategies towards the synthesis of (E)-3-styrylflavones (P 1.54)". Trabalho apresentado em 13th National Meeting of Portuguese Society of Chemistry, 2013.
  8. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.. "3-Styrylflavones synthesis: Heck versus Wittig reactions (P-0279)". Trabalho apresentado em 4th EuCheMS Chemistry Congress, 2012.
  9. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.;; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "Synthesis of 3-styrylflavones and their transformation into 2-arylbenzo[c]xanthones (QO-CP 026)". Trabalho apresentado em 12th National Meeting of Chemistry, 2011.
  10. Rocha, Djenisa H.A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.. "Polyhydroxy 3-aroylflavones as potential antioxidant agentes (P47)". Trabalho apresentado em North West Organic Chemistry, 2010.
  11. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "New synthesis of 3-styrylflavones (P38)". Trabalho apresentado em 2nd Portuguese Young Chemists Meeting – 2PYCheM, 2010.
  12. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "Studies on the Heck reaction of 3-bromoflavones with styrenes (CP59)". Trabalho apresentado em 8th National Meeting of Organic Chemistry, 2009.
Tese / Dissertação
  1. Silva, Artur Manuel Soares da; Pinto, Diana Claúdia Gouveia Alves; Rocha, Djenisa Helene Ascenção. "Estudos de síntese e transformação de cromonas e 4-quinolonas". Doutoramento, 2015. http://hdl.handle.net/10773/14472.
  2. Pinto, Diana Cláudia Gouveia Alves; Silva, Artur Manuel Soares da; Rocha, Djenisa Helene Ascenção. "Estudos da reacção de Heck de 3-bromoflavonas com estirenos". Mestrado, 2009. http://hdl.handle.net/10773/4551.

Propriedade Intelectual

Patente
  1. João F. Mano; João M. M. Rodrigues; Luís P. G. Monteiro; Djenisa H. A. Rocha. 2024. "POLISSACARÍDEOS NATURAIS CARREGADOS POSITIVA OU NEGATIVAMENTE, METODOLOGIA PARA A OBTENÇÃO DOS MESMOS E APLICAÇÕES". Portugal.
    Concedida/Emitida
  2. João F. Mano; João Borges; Vera Sousa; Djenisa H. A. Rocha. 2023. "HIDROGÉIS SUPRAMOLECULARES DE G-QUADRUPLEXOS, PROCESSOS DE PRODUÇÃO E USO DOS MESMOS". Portugal.
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/06 Aplicação, otimização e monitorização laboratorial da extração com CO2 supercrítico de compostos voláteis off-flavors da cortiça Company event: Actividade 3, Tarefa 1. Gcork Project; Amorin Cork
(Portugal)
2021/08 Customizable and regioselective NH functionalization of nucleobases towards advanced biopolymer conjugates for biomedicine IUPAC Word Chemistry Congress Virtual
2021/05 Regioselective NH functionalization of DNA nucleobases towards advanced biopolymer conjugates for biomedical applications 7 th Portuguese Young Chemists Meeting
(Bragança)
2018/01/17 The footprint of organic chemistry in the synthesis of xanthone and acridone scaffolds (OC8, pg. 78) 12th National Meeting of Organic Chemistry and 5th Therapeutic Chemistry Meeting
(Coimbra, Portugal)
2015/12/01 Strategies towards the synthesis of new (E)-2-aryl-3-styryl-4H-chromen-4-ones and (E)-1-methyl-2-aryl-3-styrylquinolin-4(1H)-ones (OC-9, pg. 45) 11th National Meeting of Organic Chemistry and 4th Therapeutic Chemistry Meeting
(Porto, Portugal)
2013/09/04 New syntheses of potential biologically active xanthones and benzoxanthones ( IOC4, pg. 61) 10th National Meeting of Organic Chemistry and 1st Luso-Brasileiro Symposium of Organic Chemistry
(Lisboa, Portugal)
2013/09/04 Biological activities of oxygen and nitrogen heterocyclic compounds (IOC3, pg. 60) 0th National Meeting of Organic Chemistry and 1st Luso-Brasileiro Symposium of Organic Chemistry
(Lisboa, Portugal)
2012/08/13 New syntheses of novel arylxanthones (PO-39) 15th European Colloquium on Heterocyclic Chemistry
(Reading, Reino Unido)
2011/11/09 An easy synthetic approach to 1,2,3-triazole heterocycles (F-20, pg. 48) XVII Luso-Galego Meeting of Chemistry
(Pontevedra, Espanha)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021/10/01 - 2022/12/15 "Intelligent hydrogels for cartilage regeneration" The work developed in the master's thesis aimed the preparetion of CHI hydrogel that promotes cartilage regeneration, by attenuating inflammation, from the phased release of D-glucosamine units by the action of encapsulated enzymes.
Coorientador
Masters degree in Molecular Biotechnology and Bioengineering (Mestrado)
Universidade de Aveiro, Portugal
2021/03/15 - 2021/09/10 "Development of conjugates N-glucosamine/flavone with potential biological applications" This project propose the synthesis of hybrids combining N-glucosamine with flavones using simple coupling methodologies: Heck reaction. The structure of flavones and N-glucosamine was functionalyzed with specific terminal (alkene, and halogen) for doing the coupling reaction between these scaffolds.
Coorientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/09/24 - 2024/09/26 Third Annual PANACEA User Meeting NMR is a European forum for high-level discussion between academic and industrial users, and consortium partners on the latest developments in solid-state NMR spectroscopy and their applications in modern chemistry and materials research (2024/09/24 - 2024/09/26)
Encontro (Membro da Comissão Organizadora)
Universidade de Aveiro, Portugal
2024/09/22 - 2024/09/25 SMARTER 8 conference brings scientists from computation, diffraction, magnetic ressonance and other spectroscopic techniques to promote SMARTER approaches to optimally combine various techniques for structural elucidation of complex organic, inorganic and biological materials. (2024/09/22 - 2024/09/25)
Encontro (Membro da Comissão Organizadora)
Universidade de Aveiro, Portugal
2019/10/21 - 2019/10/23 3rd Training school under COST action EBNA entitled Bioinspired Adhesive Hydrogels and Polymers. Some practical experiments were shown to foreign students (2019/10/21 - 2019/10/23)
Oficina (workshop) (Coorganizador)
Universidade de Aveiro CICECO, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2021/09/21 Indolylmethyl Pyrazinoquinazoline Alkaloids inspired by the sea: Total synthesis and evaluation of antimicrobial activities
Arguente principal
Mariana da Costa Almeida (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021/03/23 - 2021/06/30 Laboratory of Biorganic Chemistry (QB). Practical classes. During these classes the students done 5 works, 3 laboratory techniques (distillations, chromatography separation, extraction and purification) and 2 chemical properties of aminoacids and carbohydrates. They has 2 discussion classes where the works were discussed and doubts were cleared. The continuous evaluation of these students was under my responsibility as well as the monitoring of classes. Laboratory of Biorganic chemistry (Licenciatura) Universidade de Aveiro, Portugal
2020/03/20 - 2020/06/07 Laboratory of Biorganic Chemistry (QB). Practical classes. The continuous evaluation of these students was under my responsibility as well as the monitoring/supervision and teaching of classes. Laboratory of biorganic Chemistry (Licenciatura) Universidade de Aveiro, Portugal
2019/09/23 - 2019/12/09 Laboratory of Organic Chemistry-Physical Chemistry (QO-QF). Practical classes. During these classes the students done 8 works, 5 laboratory techniques (distillations, dialysis, chromatography separation, extraction and purification) and 3 synthesis (chalcone, hypuric acid and benzaldazine). The students done 2 complete reports and 6 summary reports. They also had 2 discussion classes where the works were discussed and doubts were cleared. The continuous evaluation of these students was under my responsibility as well as the monitoring of classes. Laboratory QO-QF (Mestrado integrado) Universidade de Aveiro, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2022/09/02 - 2022/09/02 Evaluation of monograph for the Chair of Seminars in Biotechnology. Course : Master’s degree in Industrial and Environmental Biotechnology Tithe of monograph: 3D Printing Human-Based Nanocomposite Biomaterial Inks for Tissue Regeneration Candidate: João M. Maia Universidade de Aveiro, Portugal
2021/06 - 2021/06 Jury at the final project of BSc students - Graduation in Biochemistry Universidade de Aveiro, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024/11/21 - Atual Life MDPI
2021/12/02 - Atual Pharmaceuticals (1424-8247) MDPI
2021/01/05 - Atual International Journal of Molecular Science (IJMS) (1422-0067) MDPI
2020/10/27 - Atual Journal Molecular Structure (00222860) Elsevier
2020/10/21 - Atual Nutrients (2072-6643) MDPI
2020/09/21 - Atual Molecules (1420-3049) MDPI
2020/03/06 - Atual Marine Drugs (1660-3397) MDPI
2020/07/16 - 2023/05/12 Applied Science (2673-3161) MDPI
2022/02/12 - 2022/02/12 New Journal of Chemistry (1144-0546) Royal Society of Chemistry
2022/01/07 - 2022/01/14 Journal of Aquatic Food Product Technology Taylor and Francis Online
2021/09/06 - 2021/09/06 Materials (1996-1944) MDPI
2021/07/20 - 2021/07/20 Membranes (2077-0375) MDPI

Tutoria

Tópico Nome do aluno
2020/03/18 - Atual DNA nucleobase and polymers chemical functionalization Vera Sousa
2019/04/01 - 2019/12 DNA nucleobase chemical functionalization Mariana Machado
2019/01/02 - 2019/06/30 Synthesis and characterization of polyphenolic compounds (acetophenone and coumarin) Lakhdari Houria
2019/01/02 - 2019/06/30 Synthesis and characterization of polyphenolic compounds (acetophenone and coumarin) Brahim Cherfaoui
2018/09/30 - 2018/10/31 Cytotoxicity assays Ana Sofia Santos Dias
2018/02/05 - 2018/10 Synthesis and characterization of polyphenolic compounds Liza Saher
Distinções

Prémio

2019 Out of the Box 2019 Award

Outra distinção

2019 SYNTHESIS - Best Paper Award competition
2018 Honorable Mention in Portuguese Award for best PhD Thesis in Organic Chemistry 2017