Identificação
Identificação pessoal
- Nome completo
- Joao Carlos Bettencourt de Medeiros relvas
Nomes de citação
- Relvas, JB
- Relvas, Joao B
- Relvas, João
- Bettencourt Relvas, João
Identificadores de autor
- Ciência ID
- 2D1A-908B-05A1
- ORCID iD
- 0000-0001-7636-0924
- Google Scholar ID
- https://scholar.google.com/citations?hl=en&user=ZK0Uvf0AAAAJ
- Scopus Author Id
- 6602197103
Endereços de correio eletrónico
- jrelvas@ibmc.up.pt (Profissional)
Moradas
- Instituto de Biologia Molecular e Celular e Instituto de Investigação e Inovação em Saúde. Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Profissional)
Websites
- https://www.i3s.up.pt/research-group?x=25 (Académico)
Domínios de atuação
- Ciências Médicas e da Saúde - Medicina Básica - Neurociências
Idiomas
Idioma | Conversação | Leitura | Escrita | Compreensão | Peer-review |
---|---|---|---|---|---|
Inglês | Utilizador proficiente (C2) | Utilizador proficiente (C2) | Utilizador proficiente (C2) | Utilizador proficiente (C2) | Utilizador proficiente (C2) |
Português (Idioma materno) | |||||
Francês | Utilizador independente (B1) | Utilizador independente (B2) | Utilizador independente (B1) | Utilizador independente (B2) | Utilizador independente (B1) |
Espanhol; Castelhano | Utilizador proficiente (C1) | Utilizador proficiente (C1) | Utilizador independente (B1) | Utilizador proficiente (C1) | Utilizador independente (B2) |
Formação
Grau | Classificação | |
---|---|---|
2023
Concluído
|
Neurosciences (Título de Agregado)
Universidade do Porto Faculdade de Medicina, Portugal
|
|
1997/01
Concluído
|
Molecular Genetics (Doctor of Philosophy)
Universidade de Lisboa, Portugal
|
cum laude |
1991 - 1993/05
Concluído
|
Post-graduate student (Outros)
Instituto Gulbenkian de Ciência, Portugal
|
|
1985 - 1990
Concluído
|
Biologia (Licenciatura)
Universidade de Coimbra, Portugal
|
16/20 |
Percurso profissional
Ciência
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2008/11 - Atual | Investigador principal (carreira) (Investigação) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
2006 - 2008 | Investigador Auxiliar (carreira) (Investigação) | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
2001/10 - 2002/10 | Pós-doutorado (Investigação) | University of Cambridge, Reino Unido |
1999/10 - 2001/10 | Pós-doutorado (Investigação) | MRC Cambridge Centre for Brain Repair - University of Cambridge, Reino Unido |
1997/10 - 1999/10 | Pós-doutorado (Investigação) | Wellcome/CRC Institute for Developmental Biology and Cancer - University of Cambridge, Reino Unido |
1993/06 - 1997 | Assistente de Investigação (carreira) (Investigação) | Charing Cross & Westminster Medical School (Imperial College of Medicine), Reino Unido |
Docência no Ensino Superior
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2024 - Atual | Professor Catedrático Convidado (Docente Universitário) | Universidade do Porto Faculdade de Medicina, Portugal |
2019/01 - 2023 | Professor Associado Convidado (Docente Universitário) | Universidade do Porto Faculdade de Medicina, Portugal |
2014 - 2015 | Professor Auxiliar Convidado (Docente Universitário) | Universidade do Porto Faculdade de Ciências, Portugal |
2011 - 2012 | Professor Auxiliar Convidado (Docente Universitário) | Universidade do Porto Faculdade de Medicina, Portugal |
Cargos e Funções
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2019/12 - 2023 | Vice-Diretor | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2015/01 - 2023 | Coordinator - "Neurobiology and Neurological Disease Program" | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2010/01 - 2023 | Coordinator - Neuroscience Unit | Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
2018 - 2020 | Coordinator- Porto Campus - Discoveries Centre for Regenerative and Personalised Medicine | Discoveries Centre for Regenerative and Personalised Medicine, Portugal |
Universidade do Porto, Portugal |
Outros
Categoria Profissional Instituição de acolhimento |
Empregador | |
---|---|---|
2010 - Atual | Coordinator and Lecturer in "Módulo de Neurónios e Glia" of the PhD Program in Neurosciences | Universidade do Porto Faculdade de Medicina, Portugal |
2010 - 2022 | Scientific Coordinator of the Histology and Electron Microscopy Service - IBMC and i3S, University of Porto | Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal |
2010 - 2018 | Coordinator and Lecturer of the yearly Glia Biology Course in the Graduate Program in Areas of Basic and Applied Biology | Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal |
2002/10 - 2008/10 | Group Leader | Eidgenössische Technische Hochschule Zürich, Suiça |
2002/10 - 2008/10 | Lecturer of Cell and Molecular Biology | Eidgenössische Technische Hochschule Zürich, Suiça |
2003 - 2008 | Coordinator - Praktikum Neurobiologie | Eidgenössische Technische Hochschule Zürich, Suiça |
2003 - 2006 | Lecturer in the yearly advanced Course in Neuroscience | Eidgenössische Technische Hochschule Zürich, Suiça |
Projetos
Bolsa
Designação | Financiadores | |
---|---|---|
2023 - 2028 | CARE-IN-HEALTH - CardiovascularREsolution of INflammation to promote HEALTH
HORIZON-HLTH-2022-STAYHLTH-02-01
Team Member
|
Em curso
|
2021 - 2026 | NCBIO: Unlocking Excellence in Research and Innovation in Neurobiology and Neurological Disorders at IBMC/i3S
WIDESPREAD-06-2020 ERA Chairs, project 951923
Team Member
|
Em curso
|
2021 - 2025 | LIFESAVER - Living Impact on Fetal Evolution: Shelter-Analyze-Validate-Empower
H2020-LC-GD-2020-3
Team Member
|
Em curso
|
2022 - 2024 | ATTENUATION - Advanced therapeutic approaches in addiction: targeting neuroinflammation
PTDC/SAU-TOX/0067/2021
Team Member
|
Em curso
|
2022 - 2024 | Msense - a miniaturized biosensor technology for personalized diagnostics and monitoring of multiple sclerosis
Prémio de Investigação Científica Alfredo da Silva
Team Member
|
Em curso
|
2022 - 2023 | Brain Sense - a biosensor for the diagnosis of multiple sclerosis
Amyris Innovation BIG Impact Award
Team Member
|
Concluído
|
2021 - 2023 | Heart Failure-Chip: a miniaturized technology for self-monitoring of biomarkers in minimally or non-invasive body fluids
CaixaImpulse Validate
Team Member
|
Concluído
|
2021 - 2023 | MUSIIC - Multiple Sclerosis Investigation and Innovation Chip
Team Member
|
Concluído
|
2017 - 2022 | The Discoveries Centre for Regenerative and Precision Medicine
H2020-WIDESPREAD- TEAMMING; Project number 739572
Team Member
|
Concluído
|
2018 - 2021 | PsychoGlia - Psychostimulant-induced neuroinflammation: new insight in the crosstalk between microglia, astrocytes and neurons
PTDC/SAU-TOX/30647/2017Y
Co-Investigador Responsável (Co-IR)
|
Concluído
|
2016 - 2019 | Porto Neurosciences and Neurologic Disease Research Initiative at I3S
NORTE-01-0145-FEDER-000008
Coordinator
|
Concluído
|
2017 - 2018 | The Discoveries CTR - Setting Sails
NORTE-01-0246-FEDER-000022
Team Member
|
Concluído
|
2013 - 2017 | Neuro-Enhancement Responsible Research and Innovation (NERRI)
FP7-SCIENCE-IN-SOCIETY-2012-1
Team Member
|
Concluído
|
2013 - 2015 | Cell homeostasis, tissue organization and organism biology
Norte - 07-0124-FEDER-000003
Co-coordinator
|
Concluído
|
2007 - 2010 | Role of integrin-linked-kinase and associated molecules in myelination and remyelination of the nervous system.
PTDC/BIA-BCM/69841/2006
Investigador responsável
|
Concluído
|
2006 - 2009 | The Function of RhoA in Myelinating Cells in Development and Disease
Co-Investigador Responsável (Co-IR)
|
Concluído
|
2005 - 2009 | Neural Stem Cells: An Integrated Approach to Basic Knowledge and Therapeutic Applications; National Centre Competence in Research
(NCCR)
Team Member
|
Concluído
|
2005 - 2007 | Functional Role of cdc42 in Oligodendrocyte and Schwann Cell Biology
0-20217-04
Investigador responsável
|
|
2002 - 2005 | Beta 1 Integrin in Oligodendrocyte Differentiation
0-85060-03
Investigador responsável
|
Concluído
|
Projeto
Designação | Financiadores | |
---|---|---|
2022/01/01 - 2024/12/31 | Profilin1 at the crossroads between microglia, aging and neurodegeneration
PTDC/MED-NEU/1677/2021
Investigador responsável
|
Fundação para a Ciência e a Tecnologia
Em curso
|
2022/01/01 - 2023/06/30 | Increasing Vitamin C uptake in Microglia for halting Alzheimer´s disease
EXPL/MED-NEU/0588/2021
Investigador
|
Fundação para a Ciência e a Tecnologia
Em curso
|
2018/10/20 - 2021/10/19 | Rac1 regulation of microglia homeostasis and pro-inflammatory polarisation (Role: PI; Funding: 234,000.00EU)
PTDC/MED-NEU/31318/2017
Investigador responsável
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Instituto de Medicina Molecular João Lobo Antunes, Portugal |
Fundação para a Ciência e a Tecnologia
Em curso
|
2018 - 2021 | E-RISK (Role: participant; Funding Relvas lab: 33 250EU)
POCI-01-0145-FEDER-030356
Outra
|
Em curso
|
2016/07/01 - 2020/04/01 | Mecanismos moleculares envolvidos no reconhecimento de células com perda da E-caderina
PTDC/BIM-ONC/0281/2014
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal |
Fundação para a Ciência e a Tecnologia
Concluído
|
2016/07/01 - 2019/06/30 | Sensing dysfunctional E-cadherin cells in gastric epithelia
PTDC/BIM-ONC/0281/2014 -016586
Outra
|
Concluído
|
2016/01/01 - 2018/12/31 | Projecto ESSENCE (Delta) Portugal 2020 - SI I&DT - POCI-01-0247-FEDER-010887 (Role co-PI: 68.947EU)
POCI-01-0247-FEDER-010887
|
Concluído
|
2013/06/01 - 2015/09/30 | Mutações da Caderina-E e Novos Interactores no Cancro (MECANIC). O papel da caderina-E mutada na interação integrina-matriz
extracelular no cancro gástrico.
PTDC/BIM-ONC/0171/2012
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal |
Fundação para a Ciência e a Tecnologia
Concluído
|
2012/05/01 - 2015/09/30 | The ¿processosome¿: identification and characterization of proteins promoting oligodendrocyte process outgrowth, axon wrapping
and (re) myelination of axons (Role PI, 114.062EU)
PTDC/SAU-NMC/119937/2010
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
2013/06/01 - 2015/04/30 | Modulating Actin Dynamics during axonal regeneration: the role of adducin and profilin-1 (Co-PI. 35 000 CHF)
IRP Research Grant Contract P140
|
Concluído
|
2011/01/01 - 2014/06/30 | Rho GTPases in the myelination and remyelination of the peripheral nervous system (Role PI: 185.011,00EU)
PTDC/BIA-BCM/112730/2009
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
2011/01/01 - 2014/06/30 | Understanding the role of the axon/glia functional unit during developmental myelination and in remyelination (Role: PI 179.794EU)
PTDC/SAU-NEU/099007/2008
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
2011/04/01 - 2013/04/13 | FP7-PEOPLE-2010-IEF - 276322 - OligProcessExtension (159.650EU)
276322
|
Concluído
|
2009/03/01 - 2011/08/11 | AXOGLIA FP7 Marie Curie grant PIEF-GA-2009-236766 (165 000EU)
PIEF-GA-2009-236766
|
Concluído
|
Outro
Designação | Financiadores | |
---|---|---|
2017 - 2023 | EU Horizon 2020 -Teaming grant (Agreement: 641739) - The Discoveries Centre for Regenerative and Precision Medicine
641739
Outra
|
Em curso
|
2016/05/01 - 2019/12/30 | Porto Neurosciences and Neurologic Disease Research Initiative at I3S
NORTE-01-0145-FEDER-000008
Investigador responsável
|
Concluído
|
Produções
Publicações
Artigo em revista |
|
Capítulo de livro |
|
Pré-impressão |
|
Propriedade Intelectual
Pedido provisório de patente |
|
Outros
Empresa spin-off |
|
Outra produção |
|
Atividades
Apresentação oral de trabalho
Título da apresentação | Nome do evento Anfitrião (Local do evento) |
|
---|---|---|
2023 | Departing from a neurocentric-only view of the nervous system: the emerging roles of glia |
(Faro, Portugal)
|
2023 | Regulation of glia homeostasis by RhoGTPases comes with sex differences |
Centre for Integrative Physiology and Molecular Medicine (Homburg, Alemanha)
|
2023 | Regulation of Glial homeostasis by RhoGTPase signaling |
(Albufeira, Portugal)
|
2023 | Regulation of Glial Homeostasis: Implications for Neurological Disease |
Biotech Research and Innovation Centre (BRIC) (Copenhagen, Dinamarca)
|
2022 | Microglia goes to trial: from bystanders to presumed culprits | X Simpósio de Neurociências da UFF/ V Simpósio de Neurociências a UFF-Fiocruz
(Niterói, Brasil)
|
2021 | Glia homeostasis at i3S |
(Marvão, Portugal)
|
2021 | Glia Homeostasis |
(Brasil)
|
2021 | A revolução glial – Repensar o cérebro |
University of Brasília (Brasilia, Brasil)
|
2021 | A microglia view of neuronal homeostasis |
CNC, University of Coimbra (Coimbra, Portugal)
|
2020 | And the end of all our exploring will be to arrive where we started | EIT Health Ageing PhD School - Advanced Imaging Methods in Neuroscience
(Portugal)
|
2020 | A hora da actina: do Rio de Janeiro ao Porto |
(Brasil)
|
2019 | RhoGTPase regulation of redox homeostasis in microglia |
(Ferrara, Itália)
|
2019 | RhoGTPase signaling controls glia homeostasis |
(Lisbon, Portugal)
|
2019 | Microglia function regulation by RhoGTPases | XLV Sociedade Portuguesa de Imunologia
(Coimbra, Portugal)
|
2018 | Molecular mechanisms regulating glial homeostasis |
(Lisbon, Portugal)
|
2018 | Mechanisms of glia homeostasis: implications for neurological disease |
ITQB/IBET, Universidade Nova de Lisboa (Lisbon, Portugal)
|
2017 | Rho GTPase regulation of glia homeostasis |
(Edinburgh, Reino Unido)
|
2017 | Regulation of glial homeostasis |
(Braga, Portugal)
|
2017 | Microglia goes to trial: from bystanders to presumed culprits |
Instituto de investigação e Inovação em Saúde (i3S) (Porto, Portugal)
|
2017 | Microglia goes to trial: from bystanders to presumed culprits | Ciência falada ICVS - Seminar series
ICVS, University of Minho (Braga, Portugal)
|
2017 | Regulation of Glial homeostasis in the adult brain |
CEDOC, New University of Lisbon (Lisbon, Portugal)
|
2016 | Microglia homeostasis |
(Coimbra, Portugal)
|
2016 | RhoA regulation of microglial homeostasis |
Max Planck Institute for Molecular Medicine (Munich, Alemanha)
|
2016 | RhoA regulation of microglial homeostasis |
Departamento de Ciências Médicas, Instituto de Biomedicina - iBIMED, University of Aveiro (Aveiro, Portugal)
|
2015 | Rhocking glia and other tunes |
(Coimbra, Portugal)
|
2015 | RhoGTPase function in glia homeostasis |
Centre for Research in Molecular Medicine and Chronic Diseases (São Tiago de Compostela, Espanha)
|
2015 | RhoGTPase function in glia homeostasis |
Faculty of Medicine Universidad Autónoma Madrid (Madrid, Espanha)
|
2015 | RhoGTPases signaling regulation of glial homeostasis |
INL-International Iberian Nanotechnology Laboratory (Braga, Portugal)
|
2014 | The leading edge of myelination |
Federal University of Bahia (Bahia, Brasil)
|
2013 | The leading edge of myelination | Centre for Regenerative Medicine Seminar Series SCMR
University of Edinburgh (Edinburgh, Reino Unido)
|
2012 | PINCH signaling in myelination |
(Baltimore, Estados Unidos)
|
2012 | Regulation of myelination by cytoskeleton-associated proteins |
(Lisbon, Portugal)
|
2011 | Two PINCHs-two functions. Regulating radial sorting and autocrine Schwann cell survival in PNS development |
(Crete, Grécia)
|
2011 | The integrin-PINCH-parvin complex in nervous system myelination |
(Athens, Grécia)
|
2011 | Dois PINCH, duas funções. Relevância para o sistema nervoso periférico |
(Brasil)
|
2011 | Myelination of the Peripheral Nervous System | I International Conference on Neurophysiology
(Vila Nova de Gaia, Portugal)
|
2011 | Two PINCHs-two functions: insights in Schwann Cell biology |
(Lisbon, Portugal)
|
2011 | Rholling the wrap: insights in Schwann cell biology |
Biotech Research and Innovation Centre (BRIC) (Copenhagen, Dinamarca)
|
2011 | Two PINCHs-two functions: Regulating radials sorting and autocrine Schwann cell survival in PNS development |
Institute for Cell Biology, Swiss Federal Institute of Technology Zurich (ETHZ) (Zurich, Suiça)
|
2010 | Extracellular regulation of myelination: role of the IPP complex of proteins |
(Coimbra, Portugal)
|
2010 | Extracellular regulation of myelination |
(Faro, Portugal)
|
2010 | Extracellular regulation of myelination |
(Porto, Portugal)
|
2009 | Key roles for the IPP complex of proteins in myelination |
British Neuroscience Association Seminar Series at Edinburgh (Edinburgh, Reino Unido)
|
2009 | Extracellular regulation of myelination |
Instituto de Medicina Molecular (IMM), University of Lisbon (Lisbon, Portugal)
|
2009 | Extracellular regulation of myelination |
Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon (Lisbon, Portugal)
|
2009 | Extracellular regulation of myelinating Glia |
ICVS, University of Minho (Braga, Portugal)
|
2008 | Extracellular regulation of myelination |
(Brasil)
|
2008 | Regulation of PNS myelination by integrin-linked-kinase (ILK) and associated molecules |
(Itália)
|
2008 | Differentiation of oligodendrocytes in demyelinating diseases |
(Geneve, Suiça)
|
2008 | Extracelullar regulation of myelination |
(Porto, Portugal)
|
2007 | Extracellular signaling and the regulation of PNS and CNS myelination |
(Rio de Janeiro, Brasil)
|
2007 | Neural progenitor differentiation: oligodendrocytes and myelination |
(Coimbra, Portugal)
|
2007 | Remyelination as a regeneration paradigm |
(Ofir, Portugal)
|
2007 | Integrin signaling and downstream effectors in myelination |
Department of Materials, ETHZ (Zurich, Suiça)
|
2007 | The naked axon says: Catch me if you can! |
Institute of Anatomy, University of Zurich (Zurich, Suiça)
|
2007 | FILK it, PINCH it, and Rho’ ll it: it's getting on my nerves! |
Department of Anatomy, University of Basel (Basel, Suiça)
|
2007 | Studies on the extracellular regulation of myelination and remyelination |
INEB, University of Porto (Porto, Portugal)
|
2006 | Neural Stem Cells differentiation and repair |
(Porto, Portugal)
|
2006 | Rho GTPases in myelination |
University of Cambridge (Cambridge, Reino Unido)
|
2006 | Myelination - the nerve wraps and the rac Rhols | Developmental Biology Seminar Series
The Gurdon Institute, University of Cambridge (Cambridge, Reino Unido)
|
2005 | Rho GTPase function in myelination |
(Zurich, Suiça)
|
2005 | Integrin signaling and myelination |
CNC, University of Coimbra (Coimbra, Portugal)
|
2004 | Role of the small Rho GTPases cdc42 and rac1 in oligodendrocyte biology |
University of Tu¨bingen (Alemanha)
|
2004 | Rho GTPase cdc42 and CNS myelination |
Max-Planck-Institute for Biochemistry (Munich, Alemanha)
|
2004 | Role of the RhoGTPases cdc42 and rac1 in oligodendrocyte biology |
Max Planck Institute for Experimental Medicine (Gottingen, Alemanha)
|
2000 | Integrins, oligodendrocytes and myelin membrane formation |
Department of Neuropathology and Clinical Neuroscience, Imperial College Science and Medicine, University of London (London, Reino Unido)
|
1997 | Conversion of skin fibroblasts to the myogenic lineage |
Department of Anatomy Seminars, Charing Cross and Westminster Medical School (London, Reino Unido)
|
Orientação
Título / Tema Papel desempenhado |
Curso (Tipo) Instituição / Organização |
|
---|---|---|
2024 - Atual | Impact of mushroom nutrition on gut microbiota modulation and association with neuroprotective capacity
Coorientador
|
|
2022 - Atual | Utilization of Omega 3 and Conjugated Fatty Acids to Develop New Antiobesity Strategies
Coorientador
|
|
2022 - Atual | Nonconventional Biomarkers in Multiple Sclerosis
Coorientador
|
|
2021 - Atual | Role of cdc42 in microglia function
Orientador
|
|
2021 - Atual | Psychostimulant-induced neuroinflammation: the role of RhoGTPases in microglia
Coorientador
|
|
2020/01 - Atual | Regulation of Myelination by PINCH-Mediated Signaling
Orientador
|
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2020/01 - Atual | Unveilling the Roles of Small Rho GTPase Rac1 in Microglia Homeostasis and Activation During Neuroinflammation
Orientador
|
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2022 - 2023 | Characterisation of microglial response to environmental enrichment: the role of the RhoGTPase Rac1
Coorientador
|
|
2022 - 2023 | Modulating ascorbate transport in microglia to target learning and memory deficits in Parkinson´s disease
Coorientador
|
|
2018 - 2023 | Psychostimulants and neuroinflammation: finding critical players in the crosstalk between glial cells and neurons
Coorientador
|
|
2021 - 2022 | Impact of neuronal activity on redox balance of neurons and glia
Coorientador
|
|
2017/09 - 2022 | Mechanical principles driving microglia activation
Orientador
|
GABBA
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2021 - 2021 | More bit than bio: communicating and discussing whole Brain Emulation, Mind Uploading & Superintellingence using thought experiments
Orientador
|
|
2019 - 2020 | Alcohol intake triggers aberrant synaptic pruning and synapse loss
Orientador
|
|
2019 - 2019 | Profilin1 delivery tunes cytoskeleton dynamics towards CNS axon regeneration
Coorientador
|
|
2019 - 2019 | Two birds, one frog: evaluating the therapeutic potential of amphibian ocellatin-PT4 and -PT9 peptides for application in
leishmaniasis and neuroinflammation-related diseases
Coorientador
|
|
2018 - 2019 | Deciphering the role of RhoA in microglia inflammation
Coorientador
|
|
2018 - 2019 | Control of microglia morphodynamics by the small RhoGTPase RhoA
Orientador
|
|
2018 - 2018/10 | Mechanisms of actin cytoskeletal dynamics in oligodendrocyte biology and myelin formation
Orientador
|
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2017 - 2018 | Birds of a different feather: Pinch1 and Pinch2-mediated signaling in CNS myelination
Coorientador
|
|
2017 - 2018 | Rac1 Regulation of microglia during homeostasis and neuroinflammation
Coorientador
|
|
2017 - 2018 | Regulation of developmental myelination in the peripheral nervous system by Rho signaling
Coorientador
|
|
2017 - 2018 | Impact of SVCT2 modulation in neurodegeneration: a fly-based approach
Coorientador
|
|
2016 - 2016 | Aggregation-Promoting Factors in Neurodegenerative Diseases
Coorientador
|
|
2015 - 2015 | Towards the development of new therapeutic strategies for demyelinating diseases: a microengineering platform for the screening
of therapeutical targets promoting remyelination
Coorientador
|
|
2015 - 2015 | The oligodendrocyte processosome: novel regulators of differentiation and myelination
Orientador
|
|
2013 - 2013 | Identification and validation of new potential targets for neuroprotection following experimental demyelination
Orientador
|
|
2012 - 2012/04 | Functional Characterization of Frabin, a Protein mutant in Charcot-Marie-Tooth Disease
Coorientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
2012 - 2012/04 | Analysis of Rho GTPase signalling in peripheral nervous system development: Proteomic and functional approaches
Coorientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
2012 - 2012 | Functional Characterization of Frabin, a Protein mutant in Charcot-Marie-Tooth Disease
Coorientador
|
|
2012 - 2012 | Analysis of Rho GTPase signaling in peripheral nervous system development: Proteomic and functional approaches
Coorientador
|
|
2012 - 2012 | Identifying neuromuscular abnormalities in RhoBTB3 deficient mice, using SHIRPA
Orientador
|
|
2010 - 2010/10 | Analysis of the role of PINCH in system nervous myelination
Orientador
|
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
|
2010 - 2010 | Rnd3/RhoE interactome
Orientador
|
|
2010 - 2010 | Mielinização e remielinização do Sistema Nervoso Periférico: funções das proteínas gelsolina e profilina 1.
Orientador
|
|
2009 - 2009 | Role of the small Rho GTPase rhoA in Neural stem and progenitor cells
Orientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
2008 - 2008/12 | Integrin-linked-kinase function in nervous system myelination
Orientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
2008 - 2008/10 | Analysis of the role of TGFB signaling in central nervous myelination and remyelination
Orientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
Universidade de Coimbra, Portugal |
2008 - 2008 | Analysis of the role of the small GTPase RhoA in peripheral nervous system myelination and remyelination
Orientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
2006 - 2006 | Studies on vertebrate nervous system myelination
Orientador
|
Diss., Naturwissenschaften (Doutoramento)
Eidgenössische Technische Hochschule Zürich, Suiça
|
2006 - 2006 | Analysis of the role of integrin beta 1 and the Rho GTPases cdc42 and rac1 in central nervous myelination
Orientador
|
Eidgenössische Technische Hochschule Zürich, Suiça
|
Organização de evento
Nome do evento Tipo de evento (Tipo de participação) |
Instituição / Organização | |
---|---|---|
2023 - 2023 | XV ISN Biennal Meeting on Myelin
(2023/08/02 - 2023/08/04)
Encontro (Membro da Comissão Organizadora)
|
|
2023 - 2023 | Joint International Society of Neurochemistry-European Society of Neurochemistry (ISN-ESN) Meeting (2023/07/30 - 2023/08/10)
Encontro (Membro da Comissão Organizadora)
|
|
2023 - 2023 | XVI European Glial meeting, Glial Cells in Health and Disease (2023/07/08 - 2023/07/11)
Encontro (Membro da Comissão Organizadora)
|
|
2021 - 2021 | XV European Glial meeting, Glial Cells in Health and Disease (2021/07/07 - 2021/07/10)
Encontro (Membro da Comissão Organizadora)
|
|
2019 - 2019 | XIV European Glial meeting, Glial Cells in Health and Disease (2019/07/10 - 2019/07/13)
Encontro (Membro da Comissão Organizadora)
|
|
2019 - 2019 | Meeting of the Portuguese Society for Neuroscience (2019/05/30 - 2019/06/01)
Encontro (Membro da Comissão Científica)
|
Sociedade Portuguesa de Neurociências, Portugal |
2019 - 2019 | Discoveries Forum on Regenerative and Precision Medicine (2019/09/25 - 2019/09/27)
Encontro (Outra)
|
|
2019 - 2019 | Satellite Meeting – SPN Meeting 2019 – IV Symposium – Glia Diversity in Modulation and Neurodegeneration (2019/05/29 - 2019/05/29)
Encontro (Membro da Comissão Organizadora)
|
|
2018 - 2018 | III Symposium Portuguese Glial Meeting (2018/05/18 - 2018/05/18)
Encontro (Membro da Comissão Organizadora)
|
|
2017 - 2017 | XV Meeting of the Portuguese Society for Neuroscience (2017/05/25 - 2017/05/26)
Encontro (Membro da Comissão Científica)
|
|
2015 - 2015 | XIV Meeting of the Portuguese Society for Neuroscience (SPN2015) (2015/06/04 - 2015/06/05)
Encontro (Membro da Comissão Organizadora)
|
|
2013 - 2013 | XIII Meeting of the Portuguese Society for Neuroscience (2013/05/30 - 2013/06/01)
Encontro (Membro da Comissão Científica)
|
|
2010 - 2010 | XVII Congresso Nacional de Bioquímica (2010/12/15 - 2010/12/17)
Congresso (Membro da Comissão Científica)
|
|
2010 - 2010 | Harvard Medical School Workshop on Animal Models for Neuroscience (2010/10/18 - 2010/10/22)
Oficina (workshop) (Coorganizador)
|
|
2007 - 2007 | 2nd International Meeting of the Portuguese Society for Stem Cells and Cellular Therapy. (2007/04/27 - 2007/04/28)
Encontro (Membro da Comissão Organizadora)
|
Participação em evento
Descrição da atividade Tipo de evento |
Nome do evento Instituição / Organização |
|
---|---|---|
2023 - 2023 | Session Chair - 2nd Symposium on Alzheimer´s Disease: An update on Pathology and Therapeutics
Simpósio
|
Universidade do Porto Faculdade de Engenharia, Portugal
|
2022 - 2022 | Chair - VI Symposium Portuguese Glial Network
Simpósio
|
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
|
2022 - 2022 | Poster at The Future of Redox Biology, Siena, Italy (last author)
Encontro
|
The Future of Redox Biology |
2020 - 2020 | Session Chair - Neurosciences session, YES Meeting
Encontro
|
|
2019 - 2019 | Session Chair - XIV European Meeting on Glial Cells in Health and Disease
Encontro
|
|
2019 - 2019 | Session Chair - XVI Meeting of the Portuguese Society for Neurosciences, Lisbon
Encontro
|
|
2019 - 2019 | Session Chair - Glial Diversity in Neuromodulation and Neurodegeneration, IV Portuguese Glial Network Symposium
Simpósio
|
|
2019 - 2019 | Poster at XIV European Glial meeting, Glial Cells in Health and Disease Porto, Portugal (last author)
Encontro
|
|
2019 - 2019 | Poster at 16th Meeting of the Portuguese Society of Neurosciences, Lisbon, Portugal (last author)
Encontro
|
16th Meeting of the Portuguese Society of Neurosciences |
2018 - 2018 | Chair - III Symposium Portuguese Glial Network
Simpósio
|
|
2017 - 2017 | Poster at XIII European Glial meeting, Glial Cells in Health and Disease, Edinburgh, UK (last author)
Encontro
|
XIII European Glial meeting, Glial Cells in Health and Disease |
2016 - 2016 | Session Chair - Brain without boarders | |
2015 - 2015 | XII European Glial meeting, Glial Cells in Health and Disease, Bilbao, Spain
Encontro
|
XII European Glial meeting, Glial Cells in Health and Disease |
2015 - 2015 | Poster at 15th Meeting of the Portuguese Society for Neurosciences, Póvoa do Varzim, Portugal (last author)
Encontro
|
15th Meeting of the Portuguese Society for Neurosciences |
2013 - 2013 | Poster at 13th Meeting of the Portuguese Society for Neurosciences, Luso, Portugal (last author)
Encontro
|
13th Meeting of the Portuguese Society for Neurosciences |
2012 - 2012 | Poster at 42nd Meeting of the Society of Neuroscience, New Orleans, USA (last author)
Encontro
|
|
2011 - 2011 | Poster at 23rd ISN-ESN Meeting 2011 Athens, Greece (last author)
Encontro
|
23rd ISN-ESN Meeting 2011 |
2011 - 2011 | Poster at 41st Meeting of the Society of Neuroscience, Washington, DC, USA (last author)
Encontro
|
41st Meeting of the Society of Neuroscience |
2009 - 2009 | Poster at IX European Glial meeting, Glial Cells in Health and Disease, Paris, France (last author)
Encontro
|
IX European Glial meeting, Glial Cells in Health and Disease |
2009 - 2009 | Poster at 11th Meeting of the Portuguese Society for Neurosciences, Lisbon, Portugal (last author)
Encontro
|
11th Meeting of the Portuguese Society for Neurosciences |
2008 - 2008 | Poster at Federation of European Neuroscience Societies Forum, Geneva, Switzerland (last author)
Encontro
|
Federation of European Neuroscience Societies Forum |
2008 - 2008 | Poster at Gordon Research Conference on Myelin, Il Ciocco, Italy (last author)
Conferência
|
Gordon Research Conference on Myelin |
2007 - 2007 | Poster at 10th Meeting of the Portuguese Society for Neurosciences, Ofir, Portugal (last author)
Encontro
|
10th Meeting of the Portuguese Society for Neurosciences |
2006 - 2006 | Poster at D-Biol Symposium (ETH) Davos, Switzerland (last author)
Simpósio
|
D-Biol Symposium (ETH) |
2005 - 2005 | Poster at Satellite Meeting of the International and European Society for Neurochemistry (ISN/ESN) on Myelin Development and
Function, Irsee, Germany (last author)
Encontro
|
Satellite Meeting of the International and European Society for Neurochemistry (ISN/ESN) on Myelin Development and Function |
2004 - 2004 | Poster at Federation of European Neuroscience Societies Forum, Lisbon, Portugal (last author)
Encontro
|
Federation of European Neuroscience Societies Forum |
Júri de grau académico
Tema Tipo de participação |
Nome do candidato (Tipo de grau) Instituição / Organização |
|
---|---|---|
2023 | PhD in Ageing and Chronic Diseases (PhDOC)
Arguente principal
|
Joana Rodrigues (Doutoramento) |
2021 | GABBA doctoral Program
Vogal
|
Vitoria Brugada (Doutoramento) |
2020 | PhD in Ageing and Chronic Diseases (PhDOC)
Arguente principal
|
Sofia Neves (Doutoramento) |
2020 | PhD thesis, Department of Experimental Medical Science
Arguente principal
|
Carla Azevedo (Doutoramento) |
2020 | PhD in Health Sciences
Arguente principal
|
Susana Monteiro (Doutoramento) |
2018 | PhD in Biomedical Engineering
Arguente principal
|
Ana Rita Bento (Doutoramento) |
2018 | PhD in Pharmacy
Arguente principal
|
Gisela Santos (Doutoramento) |
2018 | Doctoral thesis of the Inter-University Doctoral Program in Aging and Chronic Diseases
Arguente principal
|
Vanessa Coelho-Santos (Doutoramento) |
2018 | PhD in Experimental Biology and Biomedicine Neurosciences and Disease
Arguente principal
|
Patrícia Morais (Doutoramento) |
2018 | PhD in Experimental Biology and Medicine
Arguente principal
|
Dominique Fernandes (Doutoramento) |
2018 | PhD in Neuroscience | Carla Jeres (Doutoramento) |
2018 | PhD in pharmacy
Arguente principal
|
Andreia Barateiro (Doutoramento) |
2018 | PhD in Biomedical Sciences
Vogal
|
Ana Rita Malheiros (Doutoramento) |
2018 | GABBA doctoral Program
Vogal
|
Filipa Neto (Doutoramento) |
2018 | Doctoral Program in Neurosciences
Vogal
|
Carina Fernandes (Doutoramento) |
2017 | PhD in Experimental Biology and Biomedicine Neurosciences and Disease
Arguente principal
|
Blanka Kerlenmeyer (Doutoramento) |
2017 | PhD in Biomedical Sciences
Vogal
|
Filipa Franquinho (Doutoramento) |
2017 | PhD Program in Biomedical Sciences
Vogal
|
Tiago Silva (Doutoramento) |
2016 | PhD in Experimental Biology and Biomedicine, Neurosciences and Disease
Arguente principal
|
Mariana Pinto (Doutoramento) |
2014 | PhD in Experimental Biology and Medicine, Neurosciences and Disease
Arguente principal
|
Graciano Leal (Doutoramento) |
2014 | PhD Program in Biomedical Sciences
Vogal
|
Maria Teresa Pinto de Almeida (Doutoramento) |
2013 | PhD in Biochemistry
Arguente principal
|
Ana Rosa Silva (Doutoramento) |
2013 | PhD in Cell Biology
Arguente principal
|
Bruno Carreira (Doutoramento) |
2013 | PhD in Biomedicine
Vogal
|
Jorge Ferreira (Doutoramento) |
2013 | GABBA doctoral Program
Vogal
|
André Sousa (Doutoramento) |
2012 | PhD thesis, School of Medicine and Veterinary Medicine
Arguente principal
|
Ana Cristina Fonseca (Doutoramento) |
2012 | PhD in Biomedical Sciences
Vogal
|
Catarina Miranda (Doutoramento) |
2011 | Doctoral Program in Neurosciences
Vogal
|
Carla Morgado (Doutoramento) |
2009 | PhD In Biomedical Sciences (Neurosciences)
Arguente principal
|
Susana Rocha (Doutoramento) |
2009 | PhD in Biomedicine
Arguente principal
|
Ana Luísa Pereira (Doutoramento) |
2008 | PhD in Cell Biology
Arguente principal
|
PhD in Cell Biology (Doutoramento) |
2008 | PhD in Cell Biology
Arguente principal
|
Liliana Bernardino (Doutoramento) |
2007 | PhD thesis, Eidgenössische Technische Hochschule ETH Zürich
Arguente principal
|
François Castagner (Doutoramento) |
Comissão de avaliação
Descrição da atividade Tipo de assessoria |
Instituição / Organização | Entidade financiadora | |
---|---|---|---|
2009 - Atual | Selection Committee for the Graduate Program in Areas of Basic and Applied Biology (GABBA) | Universidade do Porto, Portugal | |
2009 - Atual | Membro do Quadro de Avaliação de Doutoramento e Pós-Doutoramento (Biomedicina) - Fundação para a Ciência e Tecnologia (FCT-
https://www.fct.pt)
Membro
|
||
2006 - 2007 | Selection Committee for admission to the International PhD Program in Neurosciences | Eidgenössische Technische Hochschule Zürich, Suiça |
Membro de associação
Nome da associação | Tipo de participação | |
---|---|---|
2008 - Atual | Sociedade Portuguesa de Neurociências | |
2006 - Atual | American Society for Neuroscience |
Membro de comissão
Descrição da atividade Tipo de participação |
Instituição / Organização | |
---|---|---|
2024 - Atual | Member of the Executive Board of Network Glial (Treasurer) - Max Delbruck Center for Molecular Medicine (MDC), Berlin | |
2024 - Atual | Member of the External Advisory Board of the Achucarro Basque Centre for Neurosciences | |
2022 - Atual | Member of the History of Neuroscience Committee - Federation of the European Neuroscience Societies (FENS)
Membro
|
|
2019 - Atual | GABBA-Graduate Program in Areas of Basic and Applied Biology
Coordenador
|
|
2017 - Atual | Co-founder and Member of the Board of the Portuguese Glial Network
Membro
|
|
2016 - Atual | Member of the Scientific Committee for Fundação Bial
Membro
|
|
2023 - 2025 | Member of the International Society of Neuroscience Advanced School Committee - International Society of Neuroscience (ISN)
Membro
|
|
2017 - 2023 | Member of the Network Glia - Max Delbruck Center for Molecular Medicine (MDC), Berlin | |
2015 - 2023 | Member of the Scientific Committee of Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto
Membro
|
|
2010 - 2023 | Member of the Scientific and Executive Committees of Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto
Membro
|
|
2018 - 2020 | Member of the Scientific and Executive Committee of the Discoveries Centre for Regenenrative and Precision Medicine
Membro
|
|
2013 - 2016 | Member and vice-president of the Scientific Committee for Life and Health Sciences of Fundação para a Ciência e a Tecnologia |
Outro júri / avaliação
Descrição da atividade | Instituição / Organização | |
---|---|---|
2024 - Atual | Member of the Maria de Sousa Prize jury | Fundação Bial, Portugal |
2019 - Atual | Editorial board of Glia | |
2018 - Atual | Editorial Board- Glia | |
2018 - Atual | Editorial Board of Frontiers in Molecular Neuroscience | |
2012 - Atual | Editorial Board - Plos One | |
2012 - Atual | Editorial Board of Plos One | |
2011 - Atual | Editorial Board - Developmental Neuroscience | |
2000 - Atual | Ad hoc reviewer: Acta Neuropathologica, Advanced Biology, Brain Research, Cell and Molecular Life Sciences, Development, Developmental Biology, Developmental Neuroscience, European Journal Neuroscience, European Journal of Cell Biology, ELife, Experimental Neurology, FEBS Letters, Frontiers in Molecular Neuroscience, Frontiers in Cellular and Molecular Neuroscience, Glia, Human Molecular Genetics, iScience, Journal of Biological Chemistry, Journal of Neurochemistry, Journal of Neurological Sciences, Nature Communications, Neuroscience Letters | |
2000 - Atual | Ad hoc reviewer: Neurobiology of Disease, Neuroscience, Plos One, Scientific Reports, The Journal of Cell Biology, The Journal of Cell Science, The Journal of Neuroscience | |
2000 - Atual | Reviewer for Funding Agencies: ARSEP Multiple Sclerosis France, Austrian Science Fund (FWF), Bial Foundation, European Science Foundation, French National Research Foundation (ANR), Fundação para a Ciência e a Tecnologia (FCT), Israel Science Foundation (ISF), LaCaixa Foundation, Medical Research Council (MRC), Multiple Sclerosis Society Canada, Multiple Sclerosis Society Australia, National Science Foundation (NSF), Netherlands Organisation for Scientific Research (NWO)! Santa Casa da Misericórdia, Stichting Alzheimer Onderzoek, ETH | |
2023 - 2023 | Assessment Committee Member on the Appointment of an Assistant Professorship in Developmental Biology, Faculty of Science, University of Lisbon | |
2011 - 2023 | Editorial Board of Developmental Neuroscience | |
2022 - 2022 | Assessment Committee on the Appointment of an Assistant Professorship in Neurobiology, Faculty of Science, University of Lisbon | |
2018 - 2018 | Assessment Committee on the Appointment of Tenure Track/Associate Professorships in Molecular Cell Biology, Department of Molecular Biology and Genetics, Aarhus University, Denmark | |
2013 - 2013 | Assessment Committee on the Appointment for a Promotion to a Professorial Research Fellowship or a Readership in Faculty of Medicine and Dentistry, University of Bristol, UK |
Tutoria
Tópico | Nome do aluno | |
---|---|---|
2014 - Atual | PhD Program in Biomedical Sciences | Sérgio Leite |
Distinções
Outra distinção
2001 | EMBO Short Term Fellowship |
1997 | Post-doctoral Fellowship from Programa Praxis XXI (BPD/11785/97) |
1995 | Fellowship Muscular Dystrophy UK |
1991 | PhD Fellowship from Programa Praxis XXI (BD/1108/90) |