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Teresa Raquel Tremoço Dias de Abreu. Completed the Mestrado integrado in Integrated master's degree (BSc and MSc) in Pharmaceutical Sciences in 2018/09/13 by University of Coimbra, Faculty of Pharmacy . Attends the Doutoramento in Doctoral Programme in Pharmaceutical Sciences - Major in Pharmaceutical Technology by University of Coimbra, Faculty of Pharmacy since 2021. Is PhD Student in iMed.ULisboa . Published 2 articles in journals. Has 2 section(s) of books. Organized 1 event(s). Participated in 3 event(s). Has received 6 awards and/or honors. Participates and/or participated as Research Fellow in 3 project(s) and Researcher in 1 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Anticancer Immunotherapy. In her professional activities interacted with 37 collaborator(s) co-authorship of scientific papers. In her curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: CAR-T cells; solid tumors; in vitro testing
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Identificação

Identificação pessoal

Nome completo
Teresa Raquel Tremoço Dias de Abreu
Data de nascimento
1995/03/27
Género
Feminino

Nomes de citação

  • Abreu, Teresa

Identificadores de autor

Ciência ID
2E18-0BF5-6D94
ORCID iD
0000-0002-7462-3257

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B1)
Formação
Grau Classificação
2021 - 2025
Em curso
 Doctoral Programme in Pharmaceutical Sciences - Major in Pharmaceutical Technology (Doutoramento)
University of Coimbra, Faculty of Pharmacy , Portugal
2020/09 - 2021/01/07
Concluído
 Advanced Course in Academic English I (Outros)
Faculty of Letters, University of Coimbra, Portugal
 17
2013/09/13 - 2018/09/13
Concluído
 Integrated master's degree (BSc and MSc) in Pharmaceutical Sciences (Mestrado integrado)
University of Coimbra, Faculty of Pharmacy , Portugal
"CAR-T cells as an anticancer therapy: current challenges and emerging opportunities" (TESE/DISSERTAÇÃO)
 17
2007 - 2015
Concluído
 Violin Course, 7th Grade (7/8) (Outros)
Music Conservatory of Coimbra (CMC), Portugal
 14
2005 - 2011
Concluído
 Cambridge ESOL level 1: First Certificate in English B2 (Outros)
British Council, Portugal
 B
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/12 - 2021/02 Investigador (Investigação) Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
2016/11 - 2017/05 Estagiário de Investigação (Investigação) Molecular Biology and Cell Culture Laboratory, FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/02/19 - 2020/08/31 Assistente Convidado (Docente Universitário) University of Coimbra, Faculty of Pharmacy , Portugal
University of Coimbra, Faculty of Pharmacy , Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/03 - Atual PhD Student iMed.ULisboa , Portugal
Faculty of Pharmacy, University of Lisbon, Portugal
2023/02 - 2023/09 Visiting PhD Student (Pathology Department) Leids Universitair Medisch Centrum, Países Baixos
Universiteit Leiden, Países Baixos
2020/04 - 2020/05 Volunteer at COVID-19 UC Lab University of Coimbra, Portugal
Center for Neuroscience and Cell Biology (CNC), Portugal
2018/05 - 2018/08 Curricular Traineeship Program Autoridade Nacional do Medicamento e Produtos de Saúde, I.P, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2018/01 - 2018/04 Curricular Traineeship Program Farmácia São José Unipessoal Lda, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2017/07/01 - 2017/07/31 Summer Internship (Quality Control Department) Bluepharma, Portugal
University of Coimbra, Portugal
2016/09 - 2016/11 Extracurricular Internship Program Clinical Analysis Laboratory, FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2016/07/01 - 2016/07/31 Summer Internship Farmácia São José Unipessoal Lda, Portugal
University of Coimbra, Portugal
2015/10 - 2016/05 Extracurricular Internship Program Observatory of Herb-Drug Interactions (OIPM), FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
Projetos

Bolsa

Designação Financiadores
2022/01 - 2023/12 EXPL/MED-FAR/1512/2021_nuCAR/Anti-PDL1
EXPL/MED-FAR/1512/2021
Investigador
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2020/04/01 - 2021/06/30 HEALTHYAGING 2020 (BIM 7.1.4)
HEALTHYAGING 2020 (BIM 7.1.4)
Bolseiro de Investigação
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2020/05/11 - 2021/03/31 BIM-PAC CANCEL_STEM/2020/04
BIM-PAC CANCEL_STEM/2020/04
Bolseiro de Investigação
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Concluído
2018/12/16 - 2020/02/09 HEALTHYAGING 2020 (BIM 7.1.2)
CENTRO-01-0145-FEDER-000012
Bolseiro de Investigação
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
 University of Coimbra
Concluído
Produções

Publicações

Artigo em revista
  1. Fonseca, Nuno A.; Gregório, Ana C.; Mendes, Vera M.; Lopes, Rui; Abreu, Teresa; Gonçalves, Nélio; Manadas, Bruno; et al. "GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposure". Nano Today 37 (2021): 101095. http://dx.doi.org/10.1016/j.nantod.2021.101095.
    10.1016/j.nantod.2021.101095
  2. Abreu, Teresa R.; Fonseca, Nuno A.; Gonçalves, Nélio; Moreira, João Nuno. "Current challenges and emerging opportunities of CAR-T cell therapies". Journal of Controlled Release 319 (2020): 246-261. http://dx.doi.org/10.1016/j.jconrel.2019.12.047.
    10.1016/j.jconrel.2019.12.047
Capítulo de livro
  1. Abreu, Teresa; Biscaia, Mariana; Gonçalves, N.; Fonseca, Nuno A.; Moreira, João Nuno. "In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles". In Biomedicine for Cancer Therapy, editado por Hélder Santos; Flavia Fontana. Springer Nature, 2020.
    Publicado
  2. Ribeiro, Rita; Abreu, Teresa; Silva, Ana Catarina; Gonçalves, João; Moreira, João Nuno. "Insights on the Formulation of Recombinant Proteins". In Current Applications of Pharmaceutical Biotechnology, 23-54. Springer International Publishing, 2019.
    Publicado • 10.1007/10_2019_119
Poster em conferência
  1. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J.. "Poster nº 24: Nucleolin as a CAR-T cell target for solid tumors - brief notions into anti-nucleolin CAR-T cells manufacturing and in vitro testing". Trabalho apresentado em III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  2. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J. "First steps on producing and testing anti-nucleolin CAR-T cells in vitro". Trabalho apresentado em Scientific Symposium "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas", 2023.
  3. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J.. "Anti-nucleolin CAR (chimeric antigen receptor)-T cells against Triple-Negative Breast Cancer - optimizing CAR-T cells production". Trabalho apresentado em ESGCT 29th Congress in collaboration with BSGCT, 2022.
  4. Abreu, Teresa; Fonseca, Nuno A.; Moreira, João Nuno. "The role of N-glycosylation on the specific binding of the tumor homing F3 peptide to nucleolin". Trabalho apresentado em BEBday 2019, 2019.
  5. Abreu, Teresa; Lopes, Rui; Fonseca, Nuno A.; Moreira, João Nuno. "Specific recognition of the onco-target nucleolin by the tumor homing F3 peptide". Trabalho apresentado em 1st Annual Meeting in Pharmaceutical Sciences, 2019.
  6. Abreu, Teresa; Moreira, João Nuno. "CAR-T cells as an Anticancer Therapy: current challenges and emerging opportunities". Trabalho apresentado em IPAP18 - Innovation in Pharmacy: Advances and Perspectives, 2018.
Resumo em conferência
  1. Abreu, Teresa; Godinho-Santos, A; Moreira, JN; Gonçalves, J. "P06.02 Anti-nucleolin CAR (chimeric antigen receptor)-T cell targeting triple-negative breast cancer - critical parameters in CAR-T cells generation". Trabalho apresentado em 9th Immunotherapy of Cancer Conference, Munique, 2022.
    Publicado • 10.1136/jitc-2022-itoc9.42
Tese / Dissertação
  1. Abreu, Teresa. "CAR-T cells as an anticancer therapy: current challenges and emerging opportunities". Mestrado, Universidade de Coimbra Faculdade de Farmácia, 2018. http://hdl.handle.net/10316/84667.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/03/04 "Potential and limitations of CAR-T cell therapies" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2023/01/24 "Generating CAR-T cells - brief comparison between research and clinical settings" (Laboratorial Course) Laboratorial Course in Advanced Therapy Medicinal Products (ATMPs)
Research Institute for Medicines ( imed.ULisboa ), Faculty of Pharmacy, University of Lisbon (Lisbon, Portugal)
2022/05/11 "Basic steps on CAR-T cells generation" (Academic Lecture) Master's Degree in Biopharmaceutical Sciences
Faculty of Pharmacy, University of Lisbon (Lisbon, Portugal)
2022/04/30 "CAR-T cell therapies: from the bench to the clinic" (Invited Oral Communication) 30ª Sabatina de Hematologia , Fórum Hematológico
University Hospital of Coimbra (CHUC) (Coimbra, Portugal)
2022/02/19 "CAR-T cell therapies - a brief introduction to their potential and limitations" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2021/11/23 "CAR-T cell therapies in solid tumors - limitations, clinical overview and monitoring" (Invited Oral Communication) Advanced Course entitled Novos avanços da citometria de fluxo nas neoplasias sólidas
University Hospital of Coimbra (CHUC) (Coimbra , Portugal)
2021/01/13 "Current challenges and emerging opportunities of CAR-T cells" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/09/27 - 2019/09/27 European Researchers' Night 2019 (2019/09/27 - 2019/09/27)
Outro (Membro da Comissão Organizadora)
 Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2021/10/12 - 2021/10/14 Representing researcher of the "Tumor microenvironment and targeted therapies" lab from the Center of Neuroscinece and Cell Biology of the University of Coimbra (CNC)
Festival
 International Festival of Science (FICA)
Camara Municipal Oeiras, Portugal
Distinções

Prémio

2023 EACR Travel Fellowship
European Association For Cancer Research, Reino Unido
2023 Best Poster of the Scientific Symposium "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas"
Ordem dos Farmaceuticos, Portugal
2018 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2017 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2016 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2015 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal