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Ana I. Matos (AIM) is currently a Junior Researcher at BioNanoSciences-Drug Delivery & Immunoengineering lab led by Prof. Helena Florindo at iMed.ULisboa (Research Institute for Medicines, Faculty of Pharmacy, University of Lisbon). Over the last decade, AIM's work has provided significant advances to immunotherapeutic approaches against cancer. AIM participates in national and international research projects covering multiple areas, such as the development of novel therapeutic vaccines and targeted immune modulatory and checkpoint therapies, where the nanotechnology, immune delivery, cancer immunology and immunotherapy research fields were bridged to develop combinatorial approaches against melanoma, colorectal, pancreatic and breast cancers. AIM's expertise has been an additional value to take advantage of novel functionalized nanomedicines to deliver combinations of bioactive molecules targeting distinct cell populations, namely dendritic cells (DC), and immune, tumor or stromal cells within the tumor microenvironment, to overcome immunosuppressive and evasion mechanisms and thereby control metastasis and disease recurrence. AIM earned her PhD in 2020 in Biomedical Engineering (TÉCNICO LISBOA). During her PhD studies she engineered a nanotechnology-based immunotherapy to re-educate host immunity against solid tumors. She demonstrated the synergism between this nano-immunotherapy, the checkpoint inhibitor anti-PD-1 and the polarization of macrophages into the pro-inflammatory phenotype, in colorectal cancer and melanoma mouse models. This project resulted in 2 first-author publications in a high impact journals, 2 oral presentations and 11 posters. From 2020 to 2023, AIM secured a Post-Doctoral position in “la Caixa”-funded international consortium (NanoPanther, LCF/PR/HR19/52160021, 1M€) designing nano-based tools as potential immunotherapies against pancreatic cancer, involving iMed.ULisboa (Lisboa, Portugal), Prince Felipe Research Center (Valencia, Spain) and Tel Aviv University (TAU) (Tel Aviv, Israel). In 2023, AIM embraced as a Junior Researcher an innovative project to develop translational nanotechnology-based immunotherapy to re-educate host immune response against breast brain metastases (LCF/PR/HR22/52420016, 1M€). AIM also participated in additional projects, such as those awarded by the Portuguese Foundation for Science and Technology (FCT) focused on the development of new immunotherapies against metastatic melanoma (NanoMetBrain, PTDC/BTM-SAL/4350/2021) and breast (NxGNanoTher, UTAP-EXPL/NPN/0041/2021) cancers, being the later awarded within the University of Texas at Austin-Portugal program. AIM is also actively sharing her research outputs with scientific community and other stakeholders (patients, clinicians, biotech, pharma, public) via media and scientific conferences. Over these years, AIM participated in the writing of scientific projects submitted for national and international funding and in several collaborations that resulted in review and original manuscripts published in high-impact journals (ORCID: 0000-0002-7325-6328), such as Advanced Science, Advanced Functional Materials, and Nature Nanotechnology. AIM interacted with more than 40 authors (+7 nationalities), publishing in total 19 articles and 4 conference proceedings with an H-index of 10, a cumulative Cite Score 2023 of 324 and a total of 901 citations (Scopus). Her findings were presented at several national and international meetings (21 oral communications and 46 posters). She was supported by 5 travel grants and 5 registration awards from renowned scientific societies to participate in highly recognized international meetings, including EACR, CIMT and CRS. AIM had been part of the team of 5 FCT-funded projects, and 4 international consortiums. AIM has actively mentored national and international PhD/MSc/BSc students, fostering next-generation scientists while managing laboratory and project tasks.
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Identificação

Identificação pessoal

Nome completo
Ana Isabel Neves de Matos

Nomes de citação

  • Matos AI
  • Ana I. Matos

Identificadores de autor

Ciência ID
3E17-536B-A110
ORCID iD
0000-0002-7325-6328
Scopus Author Id
56797725000

Endereços de correio eletrónico

  • aimatos@ff.ulisboa.pt (Profissional)
  • aimatos@farm-id.pt (Profissional)
  • anaisabelmatos_89@hotmail.com (Pessoal)

Telefones

Telefone
  • 217946400 (Profissional)

Moradas

  • Instituto de Investigação do Medicamento (iMed.ULisboa). Faculdade de Farmácia da Universidade de Lisboa, Avenida Prof. Gama Pinto, Edifício H, 1649-003, Lisboa, Lisboa, Portugal (Profissional)

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Médicas e da Saúde - Ciências da Saúde - Doenças Infeciosas
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1)
Formação
Grau Classificação
2022/04
Concluído
 Leadership and Management Skills Course for Postdocs (Outros)
Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal
2015/09 - 2020/04/30
Concluído
 Biomedical Engineering (Doctor of Philosophy)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
"COMBI-CRC: combinatorial multivalent nanoplatform for colorectal cancer treatment" (TESE/DISSERTAÇÃO)
 Pass with Distinction
2017/11/15 - 2017/11/17
Concluído
 Microfabrication Workshop - Microfluidics Fabrication for Biorecognition Detection (Outros)
INESC Microsistemas e Nanotecnologias, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/10/16 - 2017/10/20
Concluído
 FLxFlow Course - Principles and Applications of Flow Cytometry (Outros)
Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal
2016/04/26 - 2016/05/06
Concluído
 Course on Laboratory Animal Science in Mouse and Zebrafish (FELASA Category B) (Outros)
Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal
2015/10 - 2015/12
Concluído
 Statistics for Begginers Course (Outros)
Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal
2011/09 - 2014/10/24
Concluído
 Biochemistry (Master)
Especialização em Major in Biochemistry
Universidade de Lisboa Faculdade de Ciências, Portugal
"Development of nanosystems for HIV vaccine delivery" (TESE/DISSERTAÇÃO)
 17 (seventeen) values (120 ECTS)
2007/09 - 2011/02/09
Concluído
 Biochemistry (Bachelor)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Kinetic characterization of bionanoconjugates of gold nanoparticles and tyrosinase for use in biosensors" (TESE/DISSERTAÇÃO)
 13 (thirteen) values (180 ECTS)
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/05/01 - Atual Junior Researcher of La Caixa Foundation funded project MultiNano@BBM (LCF/PR/HR22/52420016) entitled "Multifunctional nano-immunotherapy against breast brain metastases" Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2022/08 - Atual Team member as Post-Doctoral Researcher of FCT funded research project PTDC/BTM-SAL/4350/2021 entitled "Multifunctional nano-immunotherapy for melanoma brain metastases treatment" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
(...)
2015/01/01 - Atual Team member at iMed.ULisboa - Research Institute for Medicines (50%) (UIDP/04138/2020) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015/01/01 - Atual Team member at Instituto de Medicina Molecular - IMM (50%) (UIDP/50005/2020) Instituto de Medicina Molecular João Lobo Antunes, Portugal
Instituto de Medicina Molecular João Lobo Antunes, Portugal
2013 - Atual Laboratory Management Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
(...)
2022/04 - 2023/06 Team member as Post-Doctoral Researcher of FCT funded research project UTAP-EXPL/NPN/0041/2021 entitled "Next-generation nanomaterials to sensitize breast cancer to immunotherapy" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
(...)
2020/08/01 - 2023/04/30 Post-Doctoral Research Fellow of La Caixa Foundation funded project NanoPanTher (LCF/PR/HR19/52160021) entitled "Sensitizing pancreatic cancer to immunotherapy with multimodal precision nanomedicines" Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
(...)
2017/01/01 - 2020/12/31 Team member of COMPETE2020 / FCT funded project SAICTPAC/0019/2015 entitled "Precision oncology by innovative therapies and technologies" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2017/01/01 - 2020/09/30 Team member of ERA-NET funded project ENMed/0051/2016 entitled "Modulation of melanoma-stroma interactions using a rationally-designed nanomedicine combining BRAFi-, MEKi- and immune-therapies" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2020/01/09 - 2020/07/09 Research Fellow (BI) at ERA-NET funded project ENMed/0051/2016 entitled "Modulation of melanomastroma interactions using a rationally designed nanomedicine combining BRAFi, MEKi and immunotherapies" Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015/10/01 - 2020/05/29 PhD fellow at FCT funded reseach grant PD/BD/113959/2015 entitled "COMBI-CRC: combinatorial multivalent nanoplatform for colorectal cancer treatment" (supervisor: Prof. João P. Conde; TÉCNICO LISBOA) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015 - 2019 Team member of ERA-NET funded project ENMed/0003/2015 entitled "Targeting tumor microenvironment by a translational multivalent nanomedicine: towards an effective anticancer combination immunotherapy" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015 - 2019 Team member of FCT funded research project UTAP-ICDT/DTPFTO/ 0016/2014 entitled "Multidisciplinary Strategy to Develop Novel Multicomponent Nanoscale Systems for Immune Modulation" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015/01/01 - 2015/12/31 Team member of Programa Gilead Génese funded project PGG/037/2014 entitled "COMBI-HIV: multivalent nanoplatform to modulate immunological cells against HIV/AIDS infection" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2015/07/01 - 2015/09/30 Research Fellow at Gilead Génese funded project PGG/037/2014 entitled "COMBI-HIV: multivalent nanoplatform to modulate immunological cells against HIV/AIDS infection" Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2014/12/20 - 2015/04/19 Research Fellow (BI) at FCT funded project PTDC/SAU-FAR/119389/2010 entitled "TherMelVac - Dendritic cell-targeted peptide vaccine against melanoma by ligand-modified nanoparticles" Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2013/09/15 - 2014/10/24 MSc Research Project entitled "Development of nanosystems for HIV vaccine delivery" (supervisor: Prof. Helena Florindo) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
(...)
2013/02/01 - 2013/06/30 Research Fellow (BI) at FCT funded project PTDC/AGR-AAM/102821/2008 entitled "Plant responses to trace element toxicity: cellular mechanisms for detoxification and tolerance" Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2012/08/06 - 2012/11/23 IAESTE Research Fellow at IAESTE funded research project entitled "Phytochemical and biological studies of medicinal plants" IAESTE - The International Association for the Exchange of Students for Technical Experience, Portugal
Universidade Federal da Grande Dourados Faculdade de Ciências Agrárias, Brasil
2011/06/08 - 2012/06/30 Research Fellow (BI) at FCT funded project PTDC/QUI/66612/2006 entitled "Novel methodology to self-assembling bio-functionalized gold nanoparticles for fabrication of biosensors" Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2010/09/15 - 2011/02/07 Bachelor Research Project entitled "Kinetic characterization of bionanoconjugates of gold nanoparticles and tyrosinase for use in biosensors" (supervisor: Prof. João Cortez) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2015/10/01 - 2020/05/29 COMBI-CRC: combinatorial multivalent nanoplatform for colorectal cancer treatment
PD/BD/113959/2015
Bolseiro de Doutoramento
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Universidade de Lisboa Instituto Superior Técnico
Concluído
2012/06/08 - 2012/11/23 Phytochemical and biological studies of medicinal plants
N/A
Bolseiro de Investigação
Universidade Federal da Grande Dourados Faculdade de Ciências Agrárias, Brasil
 IAESTE - The International Association for the Exchange of Students for Technical Experience
Concluído
2011/06/08 - 2012/06/30 Novel methodology to self-assembling bio-functionalized gold nanoparticles for fabrication of biosensors
PTDC/QUI/66612/2006
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2023/05/01 - Atual Multifunctional nano-immunotherapy against breast brain metastases
LCF/PR/HR22/52420016
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Tel Aviv University, Israel
Fundação 'la Caixa'
Em curso
2022 - Atual Multifunctional nano-immunotherapy for melanoma brain metastases treatment
PTDC/BTM-SAL/4350/2021
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal

Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal

Tel Aviv University Sackler Faculty of Medicine, Israel, Israel
Fundação para a Ciência e a Tecnologia
Em curso
2022 - 2023/06/30 Next-generation nanomaterials to sensitize breast cancer to immunotherapy
UTAP-EXPL/NPN/0041/2021
Investigador
Universidade de Lisboa Faculdade de Farmácia, Portugal

Instituto de Medicina Molecular - João Lobo Antunes, Portugal, Portugal

The University of Texas at Austin, United States, Estados Unidos
Fundação para a Ciência e a Tecnologia
Em curso
2020/08/01 - 2023/04/30 Sensitizing pancreatic cancer to immunotherapy with multimodal precision nanomedicines
NanoPanTher/HR18-00589
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
La Caixa Foundation
Em curso
2017/01/01 - 2020/12/31 Precision oncology by innovative therapies and technologies
SAICTPAC/0019/2015
Team member
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2020/01/09 - 2020/07/09 Modulation of melanomastroma interactions using a rationally designed nanomedicine combining BRAFi, MEKi and immunotherapies
ENMed/0051/2016
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Em curso
2015 - 2019 NanoTumin - Targeting tumor microenvironment by a translational multivalent nanomedicine: towards an effective anticancer combination immunotherapy
ENMed/0003/2015
Team member
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2015/07/01 - 2015/09/30 COMBI-VIH: nanoplataforma multivalente para a modelação de células imunológicas para o controlo da infeção por VIH/SIDA
grant.Provided by PTCRIS: 137413
PGG/037/2014
PGG/037/2014
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Gilead Foundation
Concluído
2014/12/20 - 2015/04/19 TherMelVac- dendritic cell-targeted peptide vaccine against melanoma by ligand-modified nanoparticles
PTDC/SAU-FAR/119389/2010
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/02/01 - 2013/06/30 Plant responses to trace element toxicity: cellular mechanisms for detoxification and tolerance
PTDC/AGR-AAM/102821/2008
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Kleiner, Ron; Moura, Liane I F; Matos AI; Vaskovich, Daniela ; et al. "PO-835 Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Trabalho apresentado em American Association for Cancer Research, Orlando, Florida, 2023.
    Publicado • 10.1158/1538-7445.AM2023-835
  2. Matos AI; Peres, C; Moura, L; Carreira, B; Viana, AS; Graça, L; Gaspar, R; Conde, JP; Florindo, HF. "PO-415 Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". 2018.
    Publicado • 10.1136/esmoopen-2018-eacr25.926
  3. Moura, Liane I F; Duro-Castano, A; Peres, C; Gallon, E; Matos AI; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". 2018.
    Publicado • 10.1136/esmoopen-2018-eacr25.927
  4. Peres, Carina; Matos AI; Ana Pimenta da Gama da Silveira Viana Semedo; Graca, Luis; Préat, Véronique; Helena F Florindo. "ML-07.01.3-001: Nanoparticle-based cancer vaccine to target dendritic cells and the tumor microenvironment". 2016.
    Publicado • 10.1111/febs.13805
Artigo em revista
  1. Carvalho, Henrique M. B.; Fidalgo, Tiago A. S.; Acúrcio, Rita C.; Matos AI; Satchi-Fainaro, Ronit; Florindo, Helena F.. Autor correspondente: Matos AI. "Better, Faster, Stronger: Accelerating mRNA-Based Immunotherapies With Nanocarriers". WIREs Nanomedicine and Nanobiotechnology 16 6 (2024): http://dx.doi.org/10.1002/wnan.2017.
    Publicado • 10.1002/wnan.2017
  2. Ferro, Cláudio; Matos AI; Serpico, Luigia; Fontana, Flavia; Chiaro, Jacopo; D'Amico, Carmine; Correia, Alexandra; et al. "Selenium Nanoparticles Synergize with a KRAS Nanovaccine against Breast Cancer". Advanced Healthcare Materials (2024): http://dx.doi.org/10.1002/adhm.202401523.
    Publicado • 10.1002/adhm.202401523
  3. Peres, Carina; Matos AI; Carreira, Bárbara; Moura, Liane I. F.; Kleiner, Ron; Vaskovich-Koubi, Daniella; Reshef, Keren; et al. "Multifunctional Nanovaccine Sensitizes Breast Cancer to Immune Checkpoint Therapy". Advanced Functional Materials (2024): http://dx.doi.org/10.1002/adfm.202401749.
    Publicado • 10.1002/adfm.202401749
  4. Matos AI; Peres, Carina; Carreira, Barbara; Moura, Liane I. F.; Acúrcio, Rita C.; Vogel, Theresa; Wegener, Erik; et al. "Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors". Advanced Science 10 25 (2023): http://dx.doi.org/10.1002/advs.202300299.
    Publicado • 10.1002/advs.202300299
  5. Pires, David; Mandal, Manoj; Matos AI; Peres, Carina; Catalão, Maria João; Azevedo-Pereira, José Miguel; Satchi-Fainaro, Ronit; Florindo, Helena F.; Anes, Elsa. "Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis". Antibiotics 12 4 (2023): 729. http://dx.doi.org/10.3390/antibiotics12040729.
    Publicado • 10.3390/antibiotics12040729
  6. Peres, Carina; Matos AI; Moura, Liane I.F.; Acúrcio, Rita C.; Carreira, Barbara; Pozzi, Sabina; Vaskovich-Koubi, Daniella; et al. "Preclinical models and technologies to advance nanovaccine development". Advanced Drug Delivery Reviews 172 (2021): 148-182. http://dx.doi.org/10.1016/j.addr.2021.03.001.
    Publicado • 10.1016/j.addr.2021.03.001
  7. Carreira, Barbara; Acúrcio, Rita C.; Matos AI; Peres, Carina; Pozzi, Sabina; Vaskovich-Koubi, Daniella; Kleiner, Ron; et al. "Nanomedicines as Multifunctional Modulators of Melanoma Immune Microenvironment". Advanced Therapeutics 4 1 (2020): 2000147. http://dx.doi.org/10.1002/adtp.202000147.
    Publicado • 10.1002/adtp.202000147
  8. Conniot, João; Scomparin, Anna; Peres, Carina; Yeini, Eilam; Pozzi, Sabina; Matos AI; Kleiner, Ron; et al. "Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators". Nature Nanotechnology 14 9 (2019): 891-901. http://dx.doi.org/10.1038/s41565-019-0512-0.
    Publicado • 10.1038/s41565-019-0512-0
  9. Matos AI; Carreira, Barbara; Peres, Carina; Moura, Liane I.F.; Conniot, João; Fourniols, Thibaut; Scomparin, Anna; et al. "Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer". Journal of Controlled Release 307 (2019): 108-138. http://dx.doi.org/10.1016/j.jconrel.2019.06.017.
    Publicado • 10.1016/j.jconrel.2019.06.017
  10. Moura, Liane I. F.; Malfanti, Alessio; Peres, Carina; Matos AI; Guegain, Elise; Sainz, Vanessa; Zloh, Mire; Vicent, María J.; Florindo, Helena F.. "Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders". Materials Horizons 6 10 (2019): 1956-1973. http://dx.doi.org/10.1039/c9mh00628a.
    Publicado • 10.1039/c9mh00628a
  11. Santos, Fábio M. F.; Domínguez, Zoe; Alcaide, María M.; Matos AI; Florindo, Helena F.; Candeias, Nuno R.; Gois, Pedro M. P.; Pischel, Uwe. "Highly Efficient Energy Transfer Cassettes by Assembly of Boronic Acid Derived Salicylidenehydrazone Complexes". ChemPhotoChem 2 12 (2018): 1038-1045. http://dx.doi.org/10.1002/cptc.201800150.
    Publicado • 10.1002/cptc.201800150
  12. Sainz, Vanessa; Moura, Liane I.F.; Peres, Carina; Matos AI; Viana, Ana S.; Wagner, Angela M.; Vela Ramirez, Julia E.; et al. "a-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma". Acta Biomaterialia 76 (2018): 193-207. http://dx.doi.org/10.1016/j.actbio.2018.06.029.
    Publicado • 10.1016/j.actbio.2018.06.029
  13. Silva, Ana Luísa; Peres, Carina; Conniot, João; Matos AI; Moura, Liane; Carreira, Bárbara; Sainz, Vanessa; et al. "Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation". Seminars in Immunology 34 (2017): 3-24. http://dx.doi.org/10.1016/j.smim.2017.09.003.
    Publicado • 10.1016/j.smim.2017.09.003
  14. Santos, Fábio M. F.; Matos AI; Ventura, Ana E.; Gonçalves, João; Veiros, Luís F.; Florindo, Helena F.; Gois, Pedro M. P.. "Modular Assembly of Reversible Multivalent Cancer-Cell-Targeting Drug Conjugates". Angewandte Chemie International Edition 56 32 (2017): 9346-9350. http://dx.doi.org/10.1002/anie.201703492.
    Publicado • 10.1002/anie.201703492
  15. Peres, Carina; Matos AI; Conniot, João; Sainz, Vanessa; Zupancic, Eva; Silva, Joana M.; Graça, Luís; et al. "Poly(lactic acid)-based particulate systems are promising tools for immune modulation". Acta Biomaterialia 48 (2017): 41-57. http://dx.doi.org/10.1016/j.actbio.2016.11.012.
    Publicado • 10.1016/j.actbio.2016.11.012
  16. Santos, Fábio M. F.; Rosa, João N.; Candeias, Nuno R.; Carvalho, Cátia Parente; Matos AI; Ventura, Ana E.; Florindo, Helena F.; et al. "A Three-Component Assembly Promoted by Boronic Acids Delivers a Modular Fluorophore Platform (BASHY Dyes)". Chemistry - A European Journal 22 5 (2015): 1537-1537. http://dx.doi.org/10.1002/chem.201504919.
    Publicado • 10.1002/chem.201504919
  17. Sainz, Vanessa; Conniot, João; Matos AI; Peres, Carina; Zupanoio, Eva; Moura, Liane; Silva, Liana C.; Florindo, Helena F.; Gaspar, Rogério S.. "Regulatory aspects on nanomedicines". Biochemical and Biophysical Research Communications 468 3 (2015): 504-510. http://dx.doi.org/10.1016/j.bbrc.2015.08.023.
    Publicado • 10.1016/j.bbrc.2015.08.023
  18. Zupancic, Eva; Peres, Carina; Matos AI; Lopes, Joao; N Moreira, Joao; S Gaspar, Rogerio; F Florindo, Helena. "Translational Peptide-associated Nanosystems: Promising Role as Cancer Vaccines". Current Topics in Medicinal Chemistry 16 3 (2015): 291-313. http://dx.doi.org/10.2174/1568026615666150701115508.
    Publicado • 10.2174/1568026615666150701115508
  19. Formagio, A.S.N.; Vieira, M.C.; Volobuff, C.R.F.; Silva, M.S.; Matos AI; Cardoso, C.A.L.; Foglio, M.A.; Carvalho, J.E.. "In vitro biological screening of the anticholinesterase and antiproliferative activities of medicinal plants belonging to Annonaceae". Brazilian Journal of Medical and Biological Research 48 4 (2015): 308-315. http://dx.doi.org/10.1590/1414-431x20144127.
    Publicado • 10.1590/1414-431x20144127
  20. Niu, Yu; Matos AI; Abrantes, Luisa M.; Viana, Ana S.; Jin, Gang. "Antibody Oriented Immobilization on Gold using the Reaction between Carbon Disulfide and Amine Groups and Its Application in Immunosensing". Langmuir 28 51 (2012): 17718-17725. http://dx.doi.org/10.1021/la303032f.
    Publicado • 10.1021/la303032f
Capítulo de livro
  1. Silva, Ana L.; Moura, Liane I.F.; Carreira, Bárbara; Conniot, João; Matos AI; Peres, Carina; Sainz, Vanessa; et al. "Functional Moieties for Intracellular Traffic of Nanomaterials". In Biomedical Applications of Functionalized Nanomaterials, 399-448. Portugal: Elsevier, 2018.
    Publicado • 10.1016/b978-0-323-50878-0.00014-8
Poster em conferência
  1. .. "Mandal M, Pires D, Matos AI, Florindo HF, Anes E. Chitosan-particle-based cystatin F RNA silencing as a therapeutic strategy to improve the control of intracellular Mycobacterium tuberculosis. ESCMID Global 2025. Vienna, Austria.". Trabalho apresentado em ESCMID Global 2025, 2025.
  2. .. "Matos AI, Carreira B, Acúrcio RC, Ferreira M, Ferro C, Graça L, Satchi-Fainaro R, Florindo HF. Multidirectional Nano-Immunotherapy against Breast Brain Metastases. 5th SPLC-CRS Young Scientists Meeting: Small Pieces for Big Breakthroughs. Barcelona, Spain". Trabalho apresentado em 5th SPLC-CRS Young Scientists Meeting: Small Pieces for Big Breakthroughs, 2025.
  3. .. "Ferro C, Matos AI, Acúrcio RC, Correia A, Fontana F, Santos HA, Florindo HF. Preclinical anti-tumor immune-mediated synergy of selenium nanoparticles and a nanovaccine against breast cancer. XV iMed.ULisboa Posgraduate Students Meeting. Lisbon, Portugal.". Trabalho apresentado em iMed.ULisboa Posgraduate Students Meeting., 2024.
  4. .. "Matos AI, Peres C, Carreira B, Moura LIF, Acúrcio AC, Viana AS, Graça L, Satchi-Fainaro R, Florindo HF. Polyoxazoline Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and PD-1 blockade against Solid Tumors. XV Spanish-Portuguese Conference on Controlled Drug Delivery. Lisbon, Portugal.". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  5. .. "Santos AC, Matos AI, Florindo HF. Regulation of breast cancer extracellular matrix to boost breast cancer immunity. 14th iMed.ULisboa Postgraduate Students Meeting, Lisbon, Portugal.". 2023.
  6. .. "Rebordão R, Matos AI, Florindo HF. Charactherization of the FAK and MDSC inhibition on breast cancer immunity. 14th iMed.ULisboa Postgraduate Students Meeting, Lisbon, Portugal.". 2023.
  7. .. "Gouveia R, Matos AI, Florindo HF. Assessment of the FAK and MDSC inhibition on breast cancer immunity. XXIX Porto Cancer Meeting: Glycosylation in tumour biology and its clinical implications, The cancer bittersweet portrait. Porto, Portugal". 2023.
  8. .. "Gouveia R, Matos AI, Florindo HF. Evaluation of the FAK and MDSC inhibitors on breast cancer immunity. 4th SPLC-CRS Young Scientists Meeting: Delivering Science, Bridging Opportunities. Porto, Portugal". 2023.
  9. .. "Carreira B, Acúrcio RC, Pozzi S, Moura LIF, Matos AI, Peres C, Kleiner R, Fernandes A, Xapell S, Vaskovich D, Satchi-Fainaro R, Florindo HF. Translational nanotechnology-based cancer vaccine to re-educate host immune response against melanoma brain metastases. 4th SPLC-CRS Young Scientists Meeting: Delivering Science, Bridging Opportunities. Porto, Portugal". 2023.
  10. .. "Matos AI, Peres C, Moura LIF, Carreira B, Viana AS, Graça L, Satchi-Fainaro R, Florindo HF. Targeted nanovaccine as a powerfull platform to improve immune modulation and checkpoint therapies in colorectal cancer. 4th SPLC-CRS Young Scientists Meeting: Delivering Science, Bridging Opportunities. Porto, Portugal". 2023.
  11. .. "Acúrcio RC, Mendes N, Carreira B, Matos AI, Peres C, Vicent MJ, Satchi-Fainaro R, Florindo HF. Unlocking Pancreatic Cancer to Nano-Immunotherapy. EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine. Seville, Spain". 2022.
  12. .. "Matos AI, Peres C, Moura LIF, Carreira B, Viana AS, Graça L, Satchi-Fainaro R, Florindo HF. Targeted nanovaccine as a powerful platform to improve immune modulation and checkpoint therapies in colorectal cancer. EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine. Seville, Spain". 2022.
  13. .. "Peres C, Matos AI, Moura LIF, Carreira B, Graça L, Satchi-Fainaro R, Florindo HF. Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer. EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine. Seville, Spain". 2022.
  14. .. "Moura, Liane I F; Malfanti, Alessio; Duro-Castano, A; Dordevic, S; Matos, Ana I.; Carina G. Peres; Carreira, Bárbara; et al. "Multivalent branched polypeptide-based nanovaccine as a novel immunotherapeutic approach for melanoma". II ASPIC-ASEICA International Meeting - Current Trends of Precision Medicine in Cancer. Online event.". 2021.
  15. .. "Matos AI, Pena S, Mateus M, Carreira B, Peres C, Moura L, Viana AS, Conde JP, Graça L, Satchi-Fainaro R, Florindo HF. Targeted nanovaccine as a powerfull platform to improve immune modulation therapy in colorectal cancer. EACR-AACR-ASPIC Basic and Translational Research Conference: Tumor Microenvironment, Lisbon, Portugal". 2020.
  16. .. "Peres C, Matos AI, Moura L, Conniot J, Carreira B, Viana AS, Préat V, Graça L, Satchi-Fainaro R, Florindo HF. Multifunctional nanovaccine synergizes with immune checkpoint therapy against triple-negative breast cancer. EACR-AACR-ASPIC Basic and Translational Research Conference: Tumor Microenvironment, Lisbon, Portugal". 2020.
  17. .. "Conniot J, Scomparin A, Carreira B, Peres C, Matos AI, Acúrcio R, Moura L, Yeini E, Pozzi S, Graça L, Préat V, Satchi-Fainaro R, Florindo HF. Functionalized nanobiomaterials as novel combination immunotherapies in cancer. EACR-AACR-ASPIC Basic and Translational Research Conference: Tumor Microenvironment, Lisbon, Portugal". 2020.
  18. .. "Matos AI, Carreira B, Moura L, Peres C, Viana AS, Conde JP, Graça L, Satchi-Fainaro R, Florindo HF. Targeted nanovaccine as a powerfull platform to treat colorectal cancer. EACR-AACR-ASPIC Conference: Nanotechnology in Cancer: Engineering for Oncology, Cambridge, United Kingdom". 2019.
  19. .. "Carreira B, Scomparin A, Krivitsky A, Matos AI, Acúrcio RA, Conniot JM, Satchi-Fainaro R, Florindo HF. Precision Nanotechnology-based Therapeutics To Regulate Tumor-immune Cells Crosstalk Against Melanoma. 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, Lisbon, Portugal". 2019.
  20. .. "Matos AI, Carreira B, Peres C, Moura L, Viana AS, Conde JP, Graça L, Satchi-Fainaro R, Florindo HF. Targeted nanovaccine as a powerfull platform to treat colorectal cancer. 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, Lisbon, Portugal". 2019.
  21. .. "Peres C, Matos AI, Moura L, Conniot J, Carreira B, Viana AS, Graça L, Préat V, Satchi-Fainaro R, Florindo HF. Nanoparticle-based vaccine improved the anti-tumor efficacy of the immune checkpoint co-stimulator OX40 in breast carcinoma. 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, Lisbon, Portugal". 2018.
  22. .. "Peres C, Conniot J, Moura LIF, Matos AI, Scomparin A, Yeini E, Graca L, Préat V, Satchi-Fainaro R, Florindo HF. Polymeric nano-vaccines improved OX40 anti-tumor efficacy against breast cancer. Controlled Release Society Annual Meeting and Exposition. New York City, NY, USA". 2018.
  23. .. "Moura LIF, Duro-Castano A, Peres C, Gallon E, Sainz V, Matos AI, Vicent MJ, Florindo HF. A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma. Frontiers in Immunomodulation and Cancer Therapy. Madrid, Spain". 2018.
  24. .. "Matos AI, Peres C, Moura LIF, Carreira B, Viana AS, Graça L, Gaspar R, Conde JP, Florindo HF. Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer. EACR25: From Fundamental Insight to Rational Cancer Treatment. Amsterdam, the Netherlands". 2018.
  25. .. "Moura LIF, Duro-Castaño A, Peres C, Gallon E, Matos AI, Vicent MJ, and Florindo HF. A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma. EACR25: From Fundamental Insight to Rational Cancer Treatment. Amsterdam, the Netherlands". 2018.
  26. .. "Moura LIF, Duro-Castaño A, Peres C, Gallon E, Sainz V, Matos AI, Vicent MJ, Florindo HF. A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma. 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. Valencia, Spain". 2018.
  27. .. "Matos AI, Peres C, Moura LIF, Carreira B, Viana AS, Graça L, Gaspar R, Conde JP, Florindo HF. Multivalent polymeric nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation. 16th CIMT Annual Meeting - Pushing Frontiers in Cancer Immuntherapy. Mainz, Germany". 2018.
  28. .. "Peres C, Matos AI, Moura LIF, Conniot J, Carreira B, Scomparin A, Yeini E, Viana AS, Graça L, Préat V, Satchi-Fainaro R, Florindo HF. Nanoparticle- based vaccine improved OX40 anti-tumor efficacy in breast cancer. 16th CIMT Annual Meeting - Pushing Frontiers in Cancer Immunotherapy. Mainz, Germany". 2018.
  29. .. "Matos AI, Peres C, Moura LIF, Carreira B, Viana AS, Graça L, Gaspar R, Conde JP, Florindo HF. Multivalent PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation. 3rd ASPIC International Congress. Lisbon, Portugal". 2018.
  30. .. "Moura LIF, Duro-Castaño A, Peres C, Gallon E, Sainz V, Matos AI, Vicent MJ, Florindo HF. Multifunctional polypeptide-based platform as an anti-cancer immunotherapeutic approach for melanoma. XII Spanish-Portuguese Conference on Controlled Drug Delivery. Coimbra, Portugal". 2018.
  31. .. "Matos AI, Peres C, Moreiras H, Viana AS, Graça L, Barral D, Conde JP, Florindo HF. Multivalent polymeric nanoparticles for colorectal cancer immunotherapy and immunomodulation. 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, Lisbon, Portugal". 2017.
  32. .. "Peres C, Moura LIF, Matos AI, Sainz V, Viana AS, Gaspar RS, Graça L, Préat V, Florindo HF. Polymeric nanoparticles as cancer vaccines and immunomodulators. 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, Lisbon, Portugal". 2017.
  33. .. "Sainz V, Peres C, Moura LIF, Matos AI, Viana AS, Lopes JA, Gaspar MM, Brocchini S, Zloh M, Florindo HF. Hybrid Lipid-Polymeric Nanoparticles for the Treatment of Melanoma by Strengthening the Host Immune Response. 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, Lisbon, Portugal". 2017.
  34. .. "Moura LIF, Duro-Caetano A, Peres C, Gallon E, Sainz V, Matos A, Gaspar G, Vicente MJ, Florindo HF. A novel multifunctional star-shaped polypeptide-based platform as an anti-cancer immunotherapeutic approach. GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer; Mount Snow, West Dover (VT), USA". 2017.
  35. .. "Matos AI, Peres C, Moreiras H, Viana AS, Graça L, Barral D, Gaspar R, Conde JP, Florindo HF. Multivalent polymeric based biodegradable nanoparticles for colorectal cancer immunotherapy and immunomodulation. GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer; Mount Snow, West Dover (VT), USA". 2017.
  36. .. "Peres C, Moura LIF, Matos AI, Sainz V, Viana AS, Gaspar RS, Graça L, Préat V, Florindo HF. Polymeric nanoparticles as breast cancer vaccines and immunomodulators. GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer; Mount Snow, West Dover (VT), USA". 2017.
  37. .. "Florindo HF, Zupancic E, Peres C, Sainz V, Matos AI, Moura LIF, Curato C, Yeini E, Jung S, and Satchi-Fainaro R. Multicomponent Nanoscale Systems for Immune Modulation Against Solid Tumors. Frontiers in Cancer Immunotherapy, New York, USA". 2017.
  38. .. "Peres C, Sainz V, Matos AI, Viana AS, Moura LIF, Graça L, Préat V and Florindo HF. Multicomponent aliphatic polyester-based nanoparticles for antigen delivery and immune modulation against cancer disease. NanoBio&Med2016 Conference, Barcelona, Spain". 2016.
  39. .. "Peres C, Matos AI, Santos AC, Viana AS, Gonçalves J, Graça L, Gaspar R, Préat V, Florindo HF. UT Austin Team: Angela M. Wagner, Julia Vela, Nicholas A. Peppas. Polymeric nanoparticle-based vaccine to target dendritic cells and the tumor microenvironment. UT Austin | Portugal Annual Conference". 2016.
  40. .. "Peres C, Matos AI, Viana AS, Graça L, Préat V, Florindo HF. Polymeric nanoparticle-based vaccine to target dendritic cells and the tumor microenvironment. 14th CIMT Annual Meeting, Mechanisms of efficacy in cancer immunotherapy, Mainz, Germany". 2016.
  41. .. "Sainz V, Matos AI, Viana AS, Lopes JA, Brocchini S, Zloh M, Florindo HF. Promising melanoma therapeutic cancer vaccine based on hybrid lipid-polymeric nanoparticles. 14th CIMT Annual Meeting, Mechanisms of efficacy in cancer immunotherapy, Mainz, Germany". 2016.
  42. .. "Peres C, Matos AI, Viana AS, Graça L, Préat V, Florindo HF. Polymeric nanoparticle-based vaccine to deliver tumor-associated antigens and for immunomodulation. 2nd ASPIC International Congress, Porto Cancer Meeting Conference, Porto, Portugal". 2016.
  43. .. "Sainz V, Matos AI, Viana AS, Lopes JA, Brocchini S, Zloh M, Florindo HF. Hybrid lipid-polymeric nanoparticles as cancer immunotherapeutics. 2nd ASPIC International Congress, Porto Cancer Meeting Conference, Porto, Portugal". 2016.
  44. .. "Peres C, Matos AI, Viana AS, Graça L, Préat V, Florindo HF. Polymeric nanoparticle-based vaccine: targeting dendritic cells and the tumor microenvironment. XI Spanish-Portuguese Conference on Controlled Drug Delivery "Revolutionary Approaches in Nanomedicine Development". Granada, Spain". 2016.
  45. .. "Matos AI, Peres C, Ventura AE, Viana AS, Borrego P, Góis P, Silva LC, Taveira N and Florindo HF. Development of PLGA-based nanocariers for Human Immunodeficiency Virus Type 1 vaccine delivery. Molecular and Supramolecular Carriers for Imaging and Therapy Conference, FP7-PEOPLE-2012-ITN - Marie-Curie Action: "Initial Training Networks" Lisbon, Portugal". 2015.
  46. .. "Matos AI, Viana AS, Real C, Taveira N, Florindo HF. Development of polymeric nanocarriers for Human Imunodeficiency Virus type 1 vaccine delivery. 6th iMed.ULisboa Postgraduate Students Meeting, Lisbon, Portugal". 2014.
  47. .. "Matos AI, Rocha MM, Neto MM, Martins LL, Mourato MP. Determination of plant-toxicity inductors metals at a rotating-disc bismuth film electrode by anodic stripping voltammetry. III Jornadas de Electroquímica e Inovação: Nanomateriais e Electroquímica, Vila Real, Portugal". 2013.
  48. .. "Almeida I, Matos AI, Viana AS. Modified electrodes with functionalized nanoparticles assembled using in-situ dithiocarbamate chemistry. 3rd International Symposium on Surface Imaging/Spectroscopy at the Solid/Liquid Interface, Cracow, Poland". 2012.
Tese / Dissertação
  1. "COMBI-CRC: combinatorial multivalent nanoplatform for colorectal cancer treatment". Doutoramento, Universidade de Lisboa Instituto Superior Técnico, 2020.
  2. "Development of nanosystems for HIV vaccine delivery". Mestrado, Universidade de Lisboa Faculdade de Farmácia, 2014.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/05 Preclinical anti-tumor immune-mediated synergy of selenium nanoparticles and a nanovaccine against luminal B breast cancer Nanobiomed2024 International Conference
(Barcelona, Espanha)
2024/07/11 Preclinical anti-tumor immune-mediated synergy of selenium nanoparticles and a nanovaccine against breast cancer XV iMed.ULisboa Posgraduate Students Meeting
(Lisbon, Portugal)
2024/02/14 Preclinical anti-tumor immune-mediated effect of selenium nanoparticles against Breast Cancer XVth Spanish-Portuguese Conference on Controlled Drug Delivery – New Horizons in Drug Delivery
(Lisbon, Portugal)
2023/11/21 Anticancer and immunological properties of selenium nanoparticles in 3D breast cancer spheroids Nanobiomed2023 International Conference
(Barcelona, Espanha)
2023/02/06 Targeted nanovaccine as a powerfull platform to improve immune modulation and checkpoint therapies in colorectal cancer 4th SPLC-CRS Young Scientists Meeting: Delivering Science, Bridging Opportunities
(Porto, Portugal)
2022/07/24 Precision Nanomedicine-based Immunotherapy to Overcome Immunosuppression Against Melanoma Brain Metastasis CRS 2022 Annual Meeting & Expo
(Montreal, Canadá)
2022/05/23 Multivalent anticancer nanovaccines ISPT 2022
(Valencia, Espanha)
2021/01/21 Multivalent branched polypeptide-based nanovaccine as promising immunotherapeutic strategy for melanoma. 3rd SPLC-CRS Young Scientists Virtual Meeting
2020/09/23 Nanotechnological approaches for immune modulation against solid cancers. NanoPT 2020
(Braga, Portugal)
2020/06/29 Nanovaccines as modulators of germinal center responses against cancer CRS Virtual Annual Meeting
2019/09/12 Multi-targeting nano-based platform as an effective immunotherapy against solid tumors. Nanotechnology in Cancer: Engineering for Oncology
(Cambridge, Reino Unido)
2018/11/20 Polymeric nano-vaccines improved immune checkpoint anti-tumor efficacy against breast cancer. NanoBio&Med2018
(Barcelona, Espanha)
2018/05/28 A Novel Multifunctional Polypeptide-Based Nanosystem As An Anti-Cancer Immunotherapeutic Approach For Melanoma 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
(Valencia, Espanha)
2017/04/23 A novel nanoplatform as metastatic melanoma cancer vaccine 1st SPLC-CRS Young Scientist Meeting
(Santiago de Compostela, Espanha)
2016/09/03 Nanoparticle-based cancer vaccine to target dendritic cells and the tumor microenvironment 41st Federation of European Biochemical Societies (FEBS) congress
(Ephesus/Kusadasi, Turquia)
2016/08/31 Nanoparticle-based cancer vaccine to target dendritic cells and the tumor microenvironment 16th FEBS Young Scientists’ Forum
(Ephesus/Kusadasi, Turquia)
2016/01/21 Development of polymeric vaccine delivery nanosystems for HIV/AIDS control through dendritic cell modulation XI Spanish-Portuguese Conference on Controlled Drug Delivery - Revolutionary Approaches in Nanomedicine Development
(Granada, Espanha)
2016/01/21 Polymeric nanoparticle-based vaccine: targeting dendritic cells and the tumor microenvironment XI Spanish-Portuguese Conference on Controlled Drug Delivery - Revolutionary Approaches in Nanomedicine Development
(Granada, Espanha)
2015/07/13 Multicomponent nanoparticles for vaccine delivery and immunomodulation Molecular and Supramolecular Carriers for Imaging and Therapy Conference, FP7-PEOPLE-2012-ITN - Marie-Curie Action: "Initial Training Networks"
(Lisboa, Portugal)
2012/08/19 New gold biosensor interfaces with ability to reduce non-specific adsorption 63rd Annual Meeting of the International Society of Electrochemistry
(Prague, República Checa)
2012/05/26 Antibody immobilization on carbon disulfide modified gold surface and Its biosensing application 2012 World Congress of Medical Physics and Biomedical Engineering (WC2012)
(Beijing, China)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/09 - 2024/07 Tumor Immune Evasion in Brain Metastases of Melanoma
Coorientador de Diogo Morim Costa
 Undergraduate research Project III of the Integrated Master in Pharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/02 - 2024/05 Regulation of tumor micro-environment against melanoma
Coorientador de Laura Debroux
 Erasmus+ trainee MSc research project of the Master in Immunology (Mestrado)
Vrije Universiteit Brussel, Bélgica

Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/02 - 2024/05 Regulation of tumor microenvironment against solid tumors
Coorientador de Catarina Pinto
 Erasmus+ trainee MSc research project of the Master in Immunology (Mestrado)
Université Paris Cité, França

Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/03 - 2023/09 Nano-immunotherapy against breast cancer
Coorientador de Tanja Schickschneit
 MSc thesis of the Master in Immunology (Erasmus+ Exchange Program) (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Otto-von-Guericke-Universität Magdeburg, Alemanha
2022/09 - 2023/09 Regulation of breast cancer extracellular matrix to boost breast cancer immunity
Coorientador de Ana Carolina Branco Santos
 MSc thesis of the Master in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/09 - 2023/09 Characterization of the FAK inhibition on breast cancer immunity
Coorientador de Raquel Ventura Rebordão Gouveia
 MSc thesis of the Master in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/06 - 2022/12 Characterization of the focal adhesion kinase (FAK) and phosphorylated focal adhesion kinase (pFAK) inhibitory effect on breast cancer immunity
Coorientador de Ana Carolina Azevedo
 Undergraduate research Project III of the Integrated Master in Pharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/06 - 2021/12 Modulation of melanoma tumor microenvironment
Coorientador de Jéssica César Luís
 Undergraduate research Project III of the Integrated Master in Pharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/06 - 2021/12 Modulation of Pancreatic Ductal Adenocarcinoma Proliferation-Associated Pathways
Coorientador de Alice Marques de Sá Gonçalves
 Undergraduate research Project III of the Integrated Master in Pharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/03 - 2021/06 Characterization of the Cancer Antigen Release Profile of Nanoparticle-based Immunotherapy
Coorientador de Maria Machado Rodrigues González
 Undergraduate research project of the degree in Cell and Molecular Biology (Licenciatura/Bacharelato)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/10 - 2020/12 Combinational nanovaccine against colorectal cancer
Coorientador de Raquel Ferreira Coelho
 MSc thesis of the Master in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/04 - 2019/06 Poly(2-oxazoline) nanoparticles for combinatorial treatment of colorectal cancer
Coorientador de Theresa Vogel
 Erasmus+ research project in Pharmaceutics and Pharmaceutical Technology (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/12 - 2018/03 Development of nanoparticulate vaccine and study of its impact on the activation of dendritic cells
Coorientador de Ana Rita Barão Lemos
 Undergraduate research Project I of the Integrated Master in Pharmaceutical Sciences (Licenciatura/Bacharelato)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/11/21 Micro and nanoformulations to improve biopharmaceutical properties of extracts obtained from olive leaf
Arguente principal
 Marta Lourenço (Mestrado)
Università degli Studi di Firenze, Itália

Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/09/23 Tumor immune evasion in brain metastases of breast cancer
Arguente principal
 Carolina Oliveira (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/12/13 Regulation of the immune response against pancreatic cancer
Arguente
 Nicole de Jesus Mendes (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/12/20 Combination of a Multifunctional Nanovaccine with Modulators of Pancreatic Cancer Microenvironment
Arguente
 Paula Cristina de Medeiros Anselmo (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/02/15 Combination immunotherapy against Pancreatic Cancer
Arguente
 Inês Raquel Domingos Vilar (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Membro de associação

Nome da associação Tipo de participação
2016 - Atual Spanish-Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)
2016 - Atual Association for Cancer Immunotherapy (CIMT)
2015 - Atual Portuguese Association for Cancer Research (ASPIC)
2015 - Atual European Association for Cancer Research (EACR)

Tutoria

Tópico Nome do aluno
2017 - Atual Mentoring of 21 BSc/MSc/PhD students from different backgrounds (Biopharmaceutical Sciences, Pharmaceutical Engenering, Pharmacy, Biochemistry) e.g. Mariana Mateus, Sandra Pena, Theresa Vogel, Raquel Coelho, Alice Gonçalves, Jéssica Luís, Cláudio Ferro
Distinções

Prémio

2022 EACR meeting bursary (travel, accommodation, and free registration awards) from the European Association for Cancer Research - EACR to attend the EACR 2022 Congress-Innovative Cancer Science:Translating Biology to Medicine, Seville, Spain(20-23 June 2022)
European Association For Cancer Research, Reino Unido
2019 EACR-Worldwide Cancer Research Meeting Bursary (travel, accommodation, and free registration awards) to attend the Nanotechnology in Cancer: Engineering for Oncology, in Cambridge, United Kingdom (12 - 14 September 2019)
European Association For Cancer Research, Reino Unido
2018 Travel grant and free registration awards to attend the 16th CIMT Annual Meeting - Pushing Frontiers in Cancer Immuntherapy, in Mainz, Germany (15 - 17 May 2018).
Association for Cancer Immunotherapy CIMT, Alemanha
2018 EACR meeting bursary (travel and free registration awards) to attend the 25th Biennial Congress - EACR25: From Fundamental Insight to Rational Cancer Treatment, in Amsterdam, the Netherlands (30 June - 3 July 2018)
European Association For Cancer Research, Reino Unido
2017 Free registration award to attend the Accelerating Cancer Immunotherapy Conference, in London, United Kingdom (29 - 30 March 2017).
European Association For Cancer Research, Reino Unido
2017 Travel award to attend the GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer, in Mount Snow, West Dover (VT), USA (18 - 23 June 2017)
TTP Labtech Ltd, Reino Unido
2015 Research project (PGG/037/2014) from Programa Gilead Génese
Gilead Sciences Lda, Portugal
2012 IAESTE Research Fellow (traineeship research grant)
IAESTE - The International Association for the Exchange of Students for Technical Experience, Portugal