???global.info.a_carregar???
Liane Moura obtained her Ph.D. in Biotechnology in 2013 (University of Coimbra). Liane is a member of the BioNanoSciences group at iMed.ULisboa. From 2014-2019, Liane was a Post-Doctoral fellow and used a rational approach to design multifunctional poly (glutamic acid)-dendrimers to target dendritic cells and co-deliver antigens and adjuvants for the activation of APC. Since 2019, Liane is a Junior Researcher in the Faculty of Pharmacy, University of Lisbon. Understanding the complexity of tumor microenvironment (TME) and how tumor-stromal-microbiota-neuro-immune cell interplay impacts the efficacy of cancer nanovaccines are major research interests of Liane. In parallel, Liane is working on the development of polymeric/polypeptide-based nanocarriers as immunotherapeutic approaches, able to conjugate and deliver different active biomolecules to immune and cancer cells, for cancer treatment. Liane has developed nano-engineered vaccines to modulate the tumor-associated microbiota and TME immune profiling for different cancers. Liane is the PI of a project “Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer”. Liane has been a core member within the team of other cancer nanoimmune-related research projects ongoing in the lab. Since 2018, Liane is involved in the support of practical classes teaching in the FFUL, having a postgraduate course in Pedagogy in Higher Education. Since 2023, Liane is a Guest Editor of Pharmaceutics Journal. Liane is the first author of 1 invited book chapter and 9 peer-reviewed international papers (plus 1 under revision) and co-author of the other 13 (plus 1 under revision; 1 submitted). She has 1688 citations and an h-index of 17 (by Scopus). The list includes top specialty journals (Nature Nanotechnology, Advanced Science, Seminars in Immunology). Liane has 20 communication abstracts published in international journals with impact factor, 29 selected oral communications, and 67 presentations as poster (2 as corresponding author). Liane has developed various collaborations and participated actively in laboratory management. She was awarded 12 grants from renowed scientific societies. She was involved in the organization of scientific meetings for the dissemination of science and she is a member of various national/international scientific societies. Liane has participated in diverse national and international funded projects (as Co-PI and team member). She supervises various undergraduate students (5 ongoing; 9 finished), master students (4 finished) as well as ERASMUS students (3 finished). Liane also participated as Jury member in Master Thesis.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Liane Moura
Data de nascimento
1986/04/01
Género
Feminino

Nomes de citação

  • Moura, Liane I F

Identificadores de autor

Ciência ID
8110-8802-8E65
ORCID iD
0000-0003-4264-6865
Google Scholar ID
https://scholar.google.pt/citations?hl=ptBR&user=iZwCbtwAAAAJ
Researcher Id
F-6534-2015
Scopus Author Id
37661789300

Endereços de correio eletrónico

  • lmoura@ff.ulisboa.pt (Profissional)
  • moura.liane@gmail.com (Pessoal)

Telefones

Telefone
  • 217946400 (Profissional)

Moradas

  • iMed.ULisboa. Avenida Professor Gama Pinto, 1649-003, Lisboa – Portugal, Lisboa, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Português (Idioma materno)
Formação
Grau Classificação
2021/10 - 2022/07/30
Concluído
 Pedagogy for the Higher Education (Pós-Graduação)
Universidade de Lisboa Instituto da Educação, Portugal
 Approved
2009/10/01 - 2013/11/05
Concluído
 Engenharia Química - Biotecnologia (Doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Development of novel therapeutic approaches for wound healing in diabetes" (TESE/DISSERTAÇÃO)
 Summa cum laude
2004 - 2008
Concluído
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Effects of natural polyphenols in angiogenesis and inflammation" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/03/01 - Atual Investigador Auxiliar (carreira) (Investigação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/12/01 - 2019/02/28 Pós-doutorado (Investigação) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/10/01 - 2016/12/30 Investigador visitante (Investigação) Biomaterials Biodegradables and Biomimetics, Portugal
Universidade do Minho, Portugal
2015/07/01 - 2016/06/30 Investigador visitante (Investigação) University of Hertfordshire Department of Pharmacy, Reino Unido

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/02/01 - Atual Assistente Estagiário (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2023 - Atual Guest Editor Pharmaceutics Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - Atual Laboratory Management Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/10 - 2023/05 Maternity Leave Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/10/01 - 2020/04/26 Maternity Leave Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2013 Laboratory Management Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/04/01 - 2009/09/30 Graduate Research fellow Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/02/01 - 2008/10/31 Undergraduated training Universidade do Porto Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2022 - 2025 Multifunctional nano-immunotherapy for melanoma brain metastases treatment
PTDC/BTM-SAL/4350/2021
member of the Research Team
Fundação para a Ciência e a Tecnologia
Em curso
2022/09/01 - 2024/03/31 Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer
Exploratory Research Projects - 2022.04506.PTDC
Investigador responsável
Fundação para a Ciência e a Tecnologia
Em curso
2022/01/01 - 2023/06/30 Next-generation nanomaterials to sensitize breast cancer to immunotherapy
UTAP-EXPL/NPN/0041/2021
Outra
The University of Texas at Austin College of Pharmacy, Estados Unidos
 Fundação para a Ciência e a Tecnologia
Concluído
2020 - 2023 Instituto de Investigação do Medicamento
UIDP/04138/2020
Outra
Em curso
2019/11 - 2020/11 HybExo-ALS - Engineering hybrid exosomes as microRNAs nanocarriers to microglia in Amyotrophic Lateral Sclerosis
100021-UID/DTP/04138/2019
Investigador responsável
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Universidade de Lisboa Instituto de Investigação do Medicamento
Concluído
2013 - 2013 Promoting endothelial progenitor cell function in diabetic wound healing
EFSD/JDRF
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Foundation for the Study of Diabetes
Concluído

Projeto

Designação Financiadores
2018 - Atual MultiNano@MBM: Modulation of melanoma-stroma interactions using a rationally-designed nanomedicine combining BRAFi-, MEKi- and immune-therapies
ENMed/0051/2016
Investigador Pós-doutorado
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018 - Atual POLYMMUNE: Off-the-Shelf Polypeptide-based Immunotherapy for Advanced Melanoma Treatment
ERC-POC: SEP-210512889
Investigador Pós-doutorado
Centro de Investigacion Principe Felipe, Espanha
 European Research Council
Concluído
2018 - Atual Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer
PTDC/QUI-QOR/29967/2017
Investigador Pós-doutorado
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2023/03/12 - 2024/09/11 Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático
2022.04506.PTDC
10.54499/2022.04506.PTDC
Fundación de la Comunidad Valenciana Centro de Investigación Príncipe Felipe, Espanha

Universidade NOVA de Lisboa NOVA Medical School, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020 - 2021 Nanomateriais para desenho de novas vacinas
UTA-EXPL/NPN/0082/2019
10.54499/UTA-EXPL/NPN/0082/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 Research Institute for Medicines
UID/DTP/04138/2019
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2018 Multidisciplinary Strategy to Develop Novel Multicomponent Nanoscale Systems for Immune Modulation.
UTAP-ICDT/DTP-FTO/0016/2014
Investigador Pós-doutorado
Fundação para a Ciência e a Tecnologia
Concluído
2012/10/01 - 2014/11/30 Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level
info:eu-repo/grantAgreement/EC/FP7/316331/EU
Bolseiro de Pós-Doutoramento
Biomaterials Biodegradables and Biomimetics, Portugal
 European Commission
Concluído
2013/06/01 - 2013/11 Anticipating diabetes and diabetic wounding for siblings of Type 2 diabetics.
EXCL/DTP-PIC/0069/2012
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia
2013/01/01 - 2013 MECHANISMS AND TREATMENT STRATEGIES OF IMPAIRED WOUND HEALING IN DIABETES
EXPL/BIM-MED/0492/2012
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012 - 2013 Neuropeptide release in wounds: a new therapeutic approach for the treatment of diabetic foot ulceration
PTDC/SAU-FAR/121109/2010
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009 - 2012 Dissecting the molecular mechanisms of wound healing in diabetes - the role of neuropeptides
PTDC/SAU-MII/098567/2008
Bolseiro de Investigação
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Carreira B; Acúrcio R; Pozzi S; Moura, Liane I F; Vaskovich D; Peres C; Fernandes A; et al. "Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Trabalho apresentado em Proceedings of the American Association for Cancer Research Annual Meeting 2023, 2023.
    10.1158/1538-7445.AM2023-835
  2. C Peres; AI Matos; Moura, Liane I F; B Carreira; M Verdial; J Conniot; MB Afonso; et al. Autor correspondente: H Florindo. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Trabalho apresentado em 46th FEBS Congress, 2022.
    Publicado • -
  3. Moura, LIF; Duro-Castano A; Peres C; Gallon E; Sainz V; Vicent MJ; Florindo H. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research, 2018.
  4. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". 2018.
    10.1136/esmoopen-2018-eacr25.927
  5. Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy-a computational design approach". Trabalho apresentado em 42nd FEBS Congress, 2017, Jerusalem, 2017.
    Publicado
  6. Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, Liane I F; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Trabalho apresentado em 53rd EASD Annual Meeting, 2017.
    Publicado
  7. Moura, Liane I F. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". 2017.
  8. Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M. "Computational design of a novel poly-glutamic dendrimer-based platform as an anticancer therapeutic approach". Trabalho apresentado em 41st FEBS Congress, 2016.
  9. Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, LIF; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Diabetes Decreases CB1 Cannabinoid Receptor Expression Promoting Early Skin Aging". Trabalho apresentado em 75th Scientific Sessions of the American Diabetes Association, 2015.
  10. Carvalho, Lina; Moura, Liane I F; Ferreira Teresa; Aguiar MJ; Dinis A; Dias, Ana M. A.; Suesca, Edward; et al. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Trabalho apresentado em 24th European Congress of Pathology, 2013.
  11. Moura, Liane I F; Dias, AM; Suesca, E; Casadiegos, S.; Duque, MF; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em Annual Meeting of Portuguese Society of Diabetology, 2013, 2013.
  12. Pirgsgalska, R; Moura, Liane I F; Espinoza, D; Koffalvi, A; Leal, EC; Carvalho, Eugénia. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Trabalho apresentado em Anual Meeting of Portuguese Society of Diabetology, 2013, 2013.
  13. Moura, Liane I F; Dias, AM; Suesca, E.; Casadiegos, S.; Duque MF; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em 48th EASD Annual Meeting, 2012.
  14. Carvalho, Lina; Moura, Liane I F; Dias, Ana M.A.; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Trabalho apresentado em European Conference of Pathology, 2012.
  15. Moura, Liane I F; Morgado, C; Pedro, JR; Lemos, C; Carvalho, Eugénia; Kofalvi, A. "Streptozotocin-induced type-1 diabetes triggers deregulation of cerebral glucose metabolism identical to genetic deletion of the CB1 cannabinoid receptor". Trabalho apresentado em 8th FENS Forum of Neuroscience 2012, 2012.
  16. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, HC; Carvalho, Eugénia. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 10º Congresso Português de Diabetes, 2012, 2012.
  17. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells in a fibrin gel". 2011.
  18. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, H.C.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 47th EASD Annual Meeting, 2011, 2011.
  19. Leal, EC; Tellechea, A; Moura, Liane I F; Veves, A; Carvalho, E. "The role of neurotensin in wound healing in diabetic and iNOS knockout mice". Trabalho apresentado em 70th Scientific Sessions of the American Diabetes Association, 2010.
Artigo em revista
  1. Peres, Carina; Matos, Ana I.; Carreira, Bárbara; Moura, Liane I. F.; Kleiner, Ron; Vaskovich-Koubi, Daniella; Reshef, Keren; et al. "Multifunctional Nanovaccine Sensitizes Breast Cancer to Immune Checkpoint Therapy". Advanced Functional Materials (2024): http://dx.doi.org/10.1002/adfm.202401749.
    10.1002/adfm.202401749
  2. Matos, Ana I. I.; Peres, Carina; Carreira, Barbara; Moura, Liane I. F.; Acurcio, Rita C. C.; Vogel, Theresa; Wegener, Erik; et al. "Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors". Advanced Science (2023): https://publons.com/wos-op/publon/55939439/.
    10.1002/ADVS.202300299
  3. Peres, C.; Matos, A. I.; Moura, L. I. F.; Carreira, B.; Verdial, M.; Conniot, J.; Afonso, M. B.; et al. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". FEBS Open Bio (2022): https://publons.com/wos-op/publon/53912188/.
  4. C. Leal, Ermelindo; F. Moura, Liane I.; Pirzgalska, Roksana M.; Marques-da-Silva, Dorinda; Ledent, Catherine; Köfalvi, Attila; Carvalho, Eugenia. "Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin". Experimental Gerontology 154 (2021): 111528. http://dx.doi.org/10.1016/j.exger.2021.111528.
    10.1016/j.exger.2021.111528
  5. Peres, Carina; Matos, Ana I.; Moura, Liane I.F.; Acúrcio, Rita C.; Carreira, Barbara; Pozzi, Sabina; Vaskovich-Koubi, Daniella; et al. "Preclinical models and technologies to advance nanovaccine development". Advanced Drug Delivery Reviews 172 (2021): 148-182. http://dx.doi.org/10.1016/j.addr.2021.03.001.
    10.1016/j.addr.2021.03.001
  6. Pedro, Joana Reis; Moura, Liane I.F.; Valério-Fernandes, Ângela; Baptista, Filipa I.; Gaspar, Joana M.; Pinheiro, Bárbara S.; Lemos, Cristina; et al. "Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes". Brain Research Bulletin 161 (2020): 106-115. http://dx.doi.org/10.1016/j.brainresbull.2020.05.004.
    10.1016/j.brainresbull.2020.05.004
  7. Conniot, João; Scomparin, Anna; Peres, Carina; Yeini, Eilam; Pozzi, Sabina; Matos, Ana I.; Kleiner, Ron; et al. "Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators". Nature Nanotechnology 14 9 (2019): 891-901. http://dx.doi.org/10.1038/s41565-019-0512-0.
    10.1038/s41565-019-0512-0
  8. Matos, Ana I.; Carreira, Barbara; Peres, Carina; Moura, Liane I.F.; Conniot, João; Fourniols, Thibaut; Scomparin, Anna; et al. "Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer". Journal of Controlled Release 307 (2019): 108-138. http://dx.doi.org/10.1016/j.jconrel.2019.06.017.
    10.1016/j.jconrel.2019.06.017
  9. Liane I.F. Moura; Cristina Lemos; Catherine Ledent; Eugénia Carvalho; Attila Köfalvi. "Chronic insulinopenia/hyperglycemia decreases cannabinoid CB1 receptor density and impairs glucose uptake in the mouse forebrain". Brain Research Bulletin 147 (2019): 101-109. https://doi.org/10.1016/j.brainresbull.2019.01.024.
    Publicado • 10.1016/j.brainresbull.2019.01.024
  10. Liane I. F. Moura; Alessio Malfanti; Carina Peres; Ana I. Matos; Elise Guegain; Vanessa Sainz; Mire Zloh; María J. Vicent; Helena F. Florindo. "Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders". Materials Horizons 6 10 (2019): 1956-1975. https://doi.org/10.1039/C9MH00628A.
    Publicado • 10.1039/C9MH00628A
  11. Moura, Liane I F; Sains, V; Peres, C; Matos, AI; Viana, AS; Wagner, AM; Ramirez, JV; et al. "a-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma". Acta Biomaterialia 76 (2018): 193-207.
    Publicado • 10.1016/j.actbio.2018.06.029
  12. Silva, Ana Luísa; Peres, Carina; Conniot, João; Matos, Ana I.; Moura, Liane; Carreira, Bárbara; Sainz, Vanessa; et al. "Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation". Seminars in Immunology 34 (2017): 3-24. http://dx.doi.org/10.1016/j.smim.2017.09.003.
    10.1016/j.smim.2017.09.003
  13. Moura, L. I. F.; Martinho, N.; Silva, L. C.; Barata, T. S.; Brocchini, S.; Florindo, H. F.; Zloh, M.; et al. "Poly-glutamic dendrimer-based conjugates for cancer vaccination – a computational design for targeted delivery of antigens". Journal of Drug Targeting 25 9-10 (2017): 873-880. http://dx.doi.org/10.1080/1061186x.2017.1363213.
    Publicado • 10.1080/1061186x.2017.1363213
  14. Moura, L.; Martinho, N.; Florindo, H.; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy - a computational design approach". The FEBS Journal (2017): https://publons.com/wos-op/publon/10909664/.
  15. Leal, E. C.; Pirzgalska, R.; Marques-da-Silva, D.; Moura, L.; Espinoza, D.; Ledent, C.; Kofalvi, A.; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Diabetologia (2017): https://publons.com/wos-op/publon/18569683/.
  16. Sainz, Vanessa; Conniot, João; Matos, Ana I.; Peres, Carina; Zupanoio, Eva; Moura, Liane; Silva, Liana C.; Florindo, Helena F.; Gaspar, Rogério S.. "Regulatory aspects on nanomedicines". Biochemical and Biophysical Research Communications 468 3 (2015): 504-510. http://dx.doi.org/10.1016/j.bbrc.2015.08.023.
    10.1016/j.bbrc.2015.08.023
  17. Moura, Liane I F; Dias, Ana M A; Suesca, Edward; Casadiegos, Sergio; Leal, Ermelindo C; Fontanilla, Marta R; Carvalho, Lina; et al. "Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 1 (2014): 32-43. http://hdl.handle.net/10316/80404.
    10.1016/j.bbadis.2013.10.009
  18. Moura, L.I.; Cruz, M.T.; Carvalho, E.. "The effect of neurotensin in human keratinocytes - implication on impaired wound healing in diabetes". Experimental Biology and Medicine 239 1 (2014): 6-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891928865&partnerID=MN8TOARS.
    10.1177/1535370213510665
  19. Pereira da Silva, Lucília; Miguel Neves, Bruno; Moura, Liane; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Decreases the Proinflammatory Status of Human Skin Fibroblasts and Increases Epidermal Growth Factor Expression". International Journal of Inflammation 2014 (2014): 1-9. http://dx.doi.org/10.1155/2014/248240.
    Publicado • 10.1155/2014/248240
  20. Moura, L.I.F.; Dias, A.M.A.; Leal, E.C.; Carvalho, L.; De Sousa, H.C.; Carvalho, E.. "Chitosan-based dressings loaded with neurotensin - An efficient strategy to improve early diabetic wound healing". Acta Biomaterialia 10 2 (2014): 843-857. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896548394&partnerID=MN8TOARS.
    10.1016/j.actbio.2013.09.040
  21. Moura, Liane I F; Dias, Ana M A; Carvalho, Eugénia; de Sousa, Hermínio C; Moura, L.I.F.; Dias, A.M.A.; Carvalho, E.; De Sousa, H.C.. "Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review". Acta Biomaterialia 9 7 (2013): 7093-7114. http://hdl.handle.net/10316/80328.
    10.1016/j.actbio.2013.03.033
  22. Moura, Liane I. F.; Silva, Lucília; Leal, Ermelindo C.; Tellechea, Ana; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Modulates the Migratory and Inflammatory Response of Macrophages under Hyperglycemic Conditions". BioMed Research International 2013 (2013): 1-13. http://dx.doi.org/10.1155/2013/941764.
    10.1155/2013/941764
  23. Carvalho, L.; Moura, L.; Ferreira, T.; d'Aguiar, M. J.; Dinis, A.; Suesca, E.; Casadiegas, S.; Fontanilla Duque, M.; de Sousa, H. C.. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Virchows Archiv (2013): https://publons.com/wos-op/publon/10403277/.
  24. Moura, L.; Dias, A.; Suesca, E.; Casadiegos, S.; Duque, M. F.; Sousa, H.; Carvalho, E.. "Neurotensin and collagen dressings improve diabetic wound healing". Diabetologia (2012): https://publons.com/wos-op/publon/5975838/.
  25. Carvalho, L.; Moura, L.; Dias, A.; Sousa, H.; Carvalho, E.. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Virchows Archiv (2012): https://publons.com/wos-op/publon/10403276/.
  26. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells". PLoS ONE 6 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79551528768&partnerID=MN8TOARS.
    10.1371/journal.pone.0016114
  27. da Silva, L.; Moura, L.; Neves, B. M.; Cruz, M. T.; Carvalho, E.; Neves, B.M.; Cruz, M.T.. "Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression". Diabetologia 1813 10 (2011): 1863-1871. https://publons.com/wos-op/publon/10403304/.
    10.1016/j.bbamcr.2011.06.018
  28. Moura, L.; Dias, A.; Leal, E.; Sousa, H.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Diabetologia (2011): https://publons.com/wos-op/publon/5975822/.
  29. Negrão, R.; Costa, R.; Duarte, D.; Taveira Gomes, T.; Mendanha, M.; Moura, L.; Vasques, L.; Azevedo, I.; Soares, R.. "Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells". Journal of Cellular Biochemistry 111 5 (2010): 1270-1279. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649890064&partnerID=MN8TOARS.
    10.1002/jcb.22850
  30. Leal, Ermelindo; Tellechea, Ana; Moura, Liane; Veves, Aristidis; Carvalho, Eugenia. "The Role of Neurotensin in Wound Healing in Diabetic and iNOS Knockout Mice". Diabetes (2010): https://publons.com/wos-op/publon/6216558/.
  31. Negrao, Rita; Moura, Liane; Duarte, Delfim; Silva, Rafael; Soares, Raquel. "Modulation effect of catechin in angiogenesis and inflammation". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403305/.
  32. Negrao, Rita; Moura, Liane; Soares, Raquel. "Establishing the molecular modulation of the inflammation by xanthohumol and its metabolites in endothelial and smooth muscle cells". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403306/.
Capítulo de livro
  1. Moura, Liane I F; Silva, Ana Luísa; Carreira, Barbara; Conniot, J; Matos, AI; Peres, C; Sainz, V.; et al. "Functional moieties for intracellular traffic of nanomaterials.". In Biomedical Applications of Functionalized Nanomaterials. Elsevier, 2018.
    Aceite para publicação
Poster em conferência
  1. Ana I. Matos; Carina Peres; Bárbara Carreira; Moura, Liane I F; Rita C. Acúrcio; Ana S. Viana; Luís Graça; Ronit Satchi-Fainaro ; Helena F. Florindo. "Polyoxazoline Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and PD-1 blockade against Solid Tumors". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  2. R.C. Acúrcio; I. C. Sanchez; Moura, Liane I F; M. J. Vicent; R. Satchi-Fainaro ; H.F. Florindo. "From cold to hot: Nanotechnology-based immunotherapy driving effective PDAC anti-tumor response". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  3. Jéssica Cordeiro; Immaculada Conejos-Sánchez; Ana I Matos; Moura, Liane I F; María J. Vicent; Helena Florindo. Autor correspondente: Moura, Liane I F. "Combined nano-immunotherapy to regulate immune profiling and tumor-associated stroma in breast cancer". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024.
  4. Silva M; Carreira B; Acúrcio R; Bonomo A; Matos AI; Moura LIF; Florindo HF. "Nano-immunotherapy for melanoma – a window of translation oncology". Trabalho apresentado em III ASPIC-ASEICA International Meeting, 2023.
  5. Cordeiro, Jéssica; CONEJOS-SANCHEZ, INMACULADA; Acúrcio, Rita C; Moura, Liane I F; María J. Vicente; Helena F Florindo. Autor correspondente: Moura, Liane I F. "Nano-immunotherapy to modulate immune cells in pancreatic cancer". Trabalho apresentado em "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas¿, 2023.
  6. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Kleiner, Ron; Vaskovich-Koubi, Daniella; et al. Autor correspondente: Helena F Florindo. "Translational nanotechnology-based cancer nanovaccine to re-educate host immune response against melanoma brain metastases". Trabalho apresentado em Gordon Research Conference on Cancer Nanotechnology and Gordon Research Seminar on Cancer Nanotechnology, 2023.
  7. Carreira, Bárbara; Rita Acúrcio; Sabina Pozzi; Moura, Liane I F; Peres, Carina; Fernandes, Adelaide; Xapelli Sara; Satchi-Fainaro, Ronit; Helena F Florindo. "Precision Nanomedicine-based Immunotherapy to Overcome Immunosuppression Against Metastatic Melanoma.". Trabalho apresentado em Champalimaud Research Symposium: Tumor Microenvironment (from cancer initiation to metastasis), 2022.
  8. Bento M; Mendes N; Moura, Liane I F; Wegener E; Jordan R, ; Conejos-Sánchez I; Vicent MJ,; Satchi-Fainaro R; Florindo HF. Autor correspondente: Florindo HF. "Multifunctional Nano-therapy to Overcome Pancreatic Cancer Immune Evasion". Trabalho apresentado em 13th iMed.ULisboa – Postgraduate Students Meeting, 2022.
  9. Peres C; Matos A; Moura, Liane I F; Carreira B; Graça L; Préat V; Satchi-Fainaro R; Florindo HF. "Targeted nanovaccine as a powerfull platform to improve immune modulation and checkpoint therapies in colorectal cancer". Trabalho apresentado em 28th Congress of the European Association for Cancer Research, 2022.
  10. Matos A; Peres C; Moura, Liane I F; Carreira B; Viana AS; Graça L; Satchi-Fainaro R; Florindo HF. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Trabalho apresentado em 28th Congress of the European Association for Cancer Research, 2022.
  11. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, A. S.; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. "Targeted nanovaccine as a powerful platform to improve immune modulation and checkpoint therapies in colorectal cancer". Trabalho apresentado em EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  12. Moura, LIF; Manfanti A; Vicent MJ; Florindo H. "Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy". Trabalho apresentado em 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022.
  13. Bento M; Moura, Liane I F; Florindo HF. "Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion". Trabalho apresentado em 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022.
  14. Moura, Liane I F; Florindo H. "Student centered teaching towards critical thinking in pharmaceutical technology". Trabalho apresentado em Jornadas Pedagógicas da Universidade de Lisboa - Ensino 4.0: Transição Digital, 2022.
  15. "Multivalent branched polypeptide-based nanovaccine as a novel immunotherapeutic approach for melanoma". Trabalho apresentado em LPCC_Cutaneous Melanoma: From Where to Where?, 2021.
    -
  16. "Precision Nanomedicine-based therapeutics to regulate immunosuppression against metastatic melanoma". Trabalho apresentado em Virtual iMed.ULisboa Meeting 2021, 2021.
    -
  17. "Multifunctional nanovaccine synergizes with OX-40 agonist in triple-negative breast cancer". Trabalho apresentado em EACR2021, 2021.
    -
  18. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Satchi-Fainaro, Ronit; Helena F Florindo. Autor correspondente: Helena F Florindo. "Precision Multifunctional Nanomedicines to Regulate Immunosuppression Against Melanoma Brain Metastasis". Trabalho apresentado em Cutaneous Melanoma: From Where to Where?,, 2021.
  19. Ana I. Matos; Pena, Sandra; Mateus, Mariana; Carreira, Bárbara; Peres, Carina; Moura, Liane I F; Viana, Ana S. or Viana, Ana; et al. "Targeted nanovaccine as a powerful platform to improve immune modulation therapy in colorectal cancer". Trabalho apresentado em EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  20. "Multifunctional nanovaccine synergizes with immune checkpoint therapy against triple-negative breast cancer". Trabalho apresentado em EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020.
    -
  21. "Targeted nanovaccine as a powerfull platform to improve immune modulation therapy in colorectal cancer". Trabalho apresentado em EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020.
    -
  22. "Functionalized nanobiomaterials as novel combination immunotherapies in cancer.". Trabalho apresentado em EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
    -
  23. Moura, Liane I F; Duro-Castano A; Malfanti A; Peres, C; Gallon E; Matos, AI; Benito AA; Vicent, MJ; Florindo, HF. "Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma". Trabalho apresentado em 17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT, 2019.
  24. Aguiam N; Moura, Liane I F; Florindo, HF; Lopes JA. "Nanotechnology in medicine and challenges for the manufacturing of nanomedicines.". Trabalho apresentado em 14th Meeting of the Spanish Society of Pharmaceutics and Pharmaceutical Technology, 2019.
  25. Matos, AI; Carreira, Barbara; Moura, Liane I F; Peres, Carina; Viana, AS; Conde, JP; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. Autor correspondente: Helena F Florindo. "Targeted nanovaccine as a powerfull platform to treat colorectal cancer.". Trabalho apresentado em EACR-AACR-ASPIC Conference: Nanotechnology in Cancer: Engineering for Oncology,, 2019.
  26. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research., 2018.
    10.1136/esmoopen-2018-eacr25.927
  27. Peres, C; Matos, AI; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Préat, V.; Satchi-Fainaro, R.; Florindo, H.F.; Graça, L. "Nanoparticle- based vaccine improved OX40 anti-tumor efficacy in breast cancer". Trabalho apresentado em 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018.
  28. Peres, Carina; Ana I. Matos; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; et al. "Nanoparticle-based vaccine improved the anti-tumor efficacy of the immune checkpoint co-stimulator OX40 in breast carcinoma". Trabalho apresentado em 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018.
  29. Florindo, H.F.; Peres, C; Conniot, J.; Moura, Liane I F; Matos, AI; Satchi-Fainaro, R.. "Polymeric nano-vaccines improved OX40 anti-tumor efficacy against breast cancer". Trabalho apresentado em Controlled Release Society Annual Meeting and Exposition., 2018.
  30. Moura, Liane I F; Duro-Castano, A; Peres, Carina; Gallon, Elena; Sainz, Vanessa; Ana I. Matos; Vicent, María J.; Helena F Florindo. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em Frontiers in Immunomodulation and Cancer Therapy, 2018.
  31. Matos, AI; Peres, C; Moura, L; Carreira, B; Viana, AS; Graça, L; Gaspar, R; Conde, JP; Florindo, HF. "PO-415 Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research, 2018.
    10.1136/esmoopen-2018-eacr25.926
  32. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogerio S; Conde, J.P.; Helena Florindo. "Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Trabalho apresentado em EACR25: From Fundamental Insight to Rational Cancer Treatment, 2018.
  33. Moura, Liane I F; Duro-Castano, A; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma.". Trabalho apresentado em 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, 2018.
  34. Matos, AI; Moura, Liane I F; Conde, JP; Florindo, HF. "Multivalent polymeric nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Trabalho apresentado em 16th CIMT Annual Meeting – Pushing Frontiers in Cancer Immunotherapy, 2018.
  35. Matos, AI; Peres, C; Moura, Liane I F; Conde, JP; Florindo, HF. "PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Trabalho apresentado em 3rd ASPIC International Congress, 2018.
  36. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogério; Conde, J.P.; Helena Florindo. "Multivalent PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation". Trabalho apresentado em 3rd ASPIC International Congress, 2018.
  37. Moura, Liane I F; Duro-Castano, A; Peres, C; Vicent, MJ; Florindo, H. F.. "Multifunctional polypeptide-based platform as an anti-cancer immunotherapeutic approach for melanoma.". Trabalho apresentado em XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  38. Moura, Liane I F; Duro-Castano, A; Peres, C; Gallon E; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma". Trabalho apresentado em Frontiers in Immunomodulation and Cancer Therapy, 2018.
  39. Moura, Liane I F; Martinho, N; Florindo, HF; Zloh, M. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach". Trabalho apresentado em 42nd FEBS Conference, 2017.
  40. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as cancer vaccines and immunomodulators". Trabalho apresentado em 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017.
  41. Sainz, Vanessa; Peres, Carina; Moura, Liane I F; Ana I. Matos; Viana, Ana S. or Viana, Ana; Lopes, João; Gaspar, Maria Manuela; et al. "Hybrid Lipid-Polymeric Nanoparticles for the Treatment of Melanoma by Strengthening the Host Immune Response". Trabalho apresentado em 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017.
  42. Moura, Liane I F; Duro-Castano, A; Vicent, MJ. "A novel multifunctional star-shaped polypeptide-based platform as an anti-cancer immunotherapeutic approach". Trabalho apresentado em Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer”, 2017.
  43. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as breast cancer vaccines and immunomodulators". Trabalho apresentado em GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer, 2017.
  44. Sainz, V.; Peres, C; Moura, Liane I F; Zloh, M; Florindo, HF. "A novel nanoplatform as metastatic melanoma cancer vaccine". Trabalho apresentado em 1st SPLC-CRS Young Scientist Meeting, 2017.
  45. Helena F Florindo; Zupancic, Eva; Peres, Carina; Sainz, Vanessa; Ana I. Matos; Moura, Liane I F; Curato, Caterina; et al. "Multicomponent Nanoscale Systems for Immune Modulation Against Solid Tumors.". Trabalho apresentado em Frontiers in Cancer Immunotherapy, 2017.
  46. Peres, Carina; Sainz, Vanessa; Ana I. Matos; Viana, Ana S. or Viana, Ana; Moura, Liane I F; Graca, Luis; Préat, Véronique; Helena F Florindo. "Multicomponent aliphatic polyester-based nanoparticles for antigen delivery and immune modulation against cancer disease". Trabalho apresentado em NanoBio&Med2016, 2016.
  47. Moura, Liane I F; Martinho, N; Florindo, H.F.; Zloh, M. "Computational design of a novel poly–glutamic dendrimer-based platform as an anticancer therapeutic approach". Trabalho apresentado em 41th FEBS Congress, 2016.
  48. Sainz, V.; Moura, Liane I F; Florindo HF. "Multicomponent nanoscale systems as metastatic melanoma therapeutic cancer vaccines". Trabalho apresentado em UT Austin|Portugal Annual Conference, 2016.
  49. Moura, Liane I F; Aroso, I; Reis, RL; Pires, RA. "Cork extracts induce a cytoprotective effect against H2O2 oxidative damage in SH--SY5Y cells". Trabalho apresentado em IV ICVS/3B´S Meeting, 2014.
  50. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em Annual Meeting of Portuguese Society of Diabetology, 2013.
  51. Pirsgalska, R; Moura, Liane I F; Espinoza, D; Leal, EC; Carvalho, E. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Trabalho apresentado em CISE 2012 Conference, 2012.
  52. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em 8th EASD Annual Meeting, 2012.
  53. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 47th EASD Annual Meeting, 2011.
  54. Moura, Liane I F; Soares Raquel; Negrão, Rita. "Effects of natural polyphenols on angiogenesis and inflammation". Trabalho apresentado em XVI National Congress of Biochemistry, 2008.
Resumo em conferência
  1. Barbara Carreira; Rita C. Acúrcio; Ana I. Matos; Liane M. Moura; Ronit Satchi-Fainaro; Helena F. Florindo. "Unlocking solid tumors to nano-immunotherapy". Trabalho apresentado em Proceedings of the American Association for Cancer Research Annual Meeting 2024, San Diego, 2024.
    Publicado • 10.1158/1538-7445.AM2024-493
  2. Carreira, Bárbara; Acúrcio, Rita C; Pozzi, Sabina; Ron Kleiner; Moura, Liane I F; Ana I. Matos; Daniella Vaskovich-Koubi; et al. Autor correspondente: Ronit Satchi. "Abstract 835: Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Trabalho apresentado em AACR Annual Meeting 2023, Orlando, 2023.
    Publicado • 10.1158/1538-7445.AM2023-835
Tese / Dissertação
  1. Moura, Liane. "Development of novel therapeutic approaches for wound healing in diabetes". Doutoramento, 2013. http://hdl.handle.net/10316/23741.

Propriedade Intelectual

Pedido provisório de patente
  1. 2019. "Cross-linked star-shaped self-assembled polypeptides as immunotherapies".
    Protegido
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/04/29 Nano-immunotherapy combination to regulate imune profiling and tumor-associated stroma in pancreatic cancer 6th ASPIC International Congress
(Faro, Portugal)
2024/02/15 Personalized neoantigen cancer nanovaccine to guide host immune response against melanoma brain metastases XV Spanish-Portuguese Conference on Controlled Drug Delivery
2022/05/23 Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice
(Valencia, Espanha)
2022/05/23 Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice
(Valencia, Espanha)
2022/04/22 Multivalent polypetide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma International Conference on Pharmaceutics and Novel Drug Delivery Systems
2021/10/15 Precision Multifunctional Nanomedicines to regulate immunosuppression against melanoma brain metastasis LPCC Cutaneous Melanoma: From Where to Where?
(Portugal)
2021/03 Immuno-engineering: nanodelivery systems as tools for immune modulation in cancer PhD Programme in Pharmacy - PhD Advanced Course in “Advanced Drug Delivery”
(Portugal)
2021/01/21 Multivalent branched polypeptide-based nanovaccine as promising immunotherapeutic strategy for melanoma 3rd SPLC-CRS Young Scientists Virtual Meeting
2020/09/23 Nanotechnological approaches for immune modulation against solid cancers. NanoPT 2020
2020/06/29 Nanovaccines as modulators of germinal center responses against cancer CRS Virtual Meeting 2020
2019/09/12 Multi-targeting nano-based platform as an effective immunotherapy against solid tumors. Nanotechnology in Cancer: Engineering for Oncology
(Cambridge, Reino Unido)
2019/05/22 Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma 17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT
(Mainz, Alemanha)
2018/11/22 Polymeric nano-vaccines improved immune checkpoint anti-tumor efficacy against breast cancer NanoBio&Med 2018
(Barcelona, Espanha)
2018/09/18 Polymer conjugates as cancer vaccines FCT PhD Programme i3DU Course on “Advanced Drug Delivery”
Universidade de Lisboa Faculdade de Farmácia (Portugal)
2018/05/28 A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
(Valencia, Espanha)
2017/11/24 Impact of multicomponent nano-vaccine on immune modulation against solid tumors NanoBio&Med2017
(Barcelona, Espanha)
2017/09/14 Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach 42nd FEBS Conference
(Jerusalem, Israel)
2017/06/18 Insights on the Impact of Controlled Multicomponent Nanoscale Systems on Immune Modulation Against Solid Tumors Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer”
(Mount Snow, Estados Unidos)
2016/01/23 Melanoma cancer vaccine based on multifunctional nanoparticles for antigen delivery and immunomodulation XI Spanish-Portuguese Conference on Controlled Drug Delivery;
(Granada, Espanha)
2012/01/27 Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment V SPB Clinical Biochemistry Workshop
(Coimbra, Portugal)
2011/12/19 Neurotensin improves diabetic wound healing via inducible nitric oxide synthase IX Annual Meeting of Center for Neuroscience and Cell Biology
(Coimbra, Portugal)
2011/09/13 Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression 47th EASD Annual Meeting
(Lisbon, Portugal)
2010/03/10 Wound healing in diabetic and iNOS knockout mice: the role of Neurotensin 9º Congresso Português de Diabetes
(Vilamoura, Portugal)
2010/01/28 Neurotensin improves wound healing in diabetic and iNOS knockout mice IV SPB Clinical Biochemistry Workshop
(Faro, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2024/01 - Atual Modulation of tumor-immune microenvironment against cancer
Coorientador
 Ciências Farmacêuticas
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual The Neuro-immune Axis in the Tumor Microenvironment
Orientador
 Ciências Farmacêuticas
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual The impact of microbiome in immunotherapy for breast cancer
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual Collagen as a wound healing material
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual Sphingosomes: A modified Lipid nanoparticle platform for mRNA delivery
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10 - Atual Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer
Orientador
2022/09/01 - 2023 Recent nanotechnological approaches for immunotherapy in type 1 diabetes
Orientador
2022/09/01 - 2022/12/15 Liposomal siRNA Formulation for the Treatment of rheumatoid arthritis
Orientador
2022/02/01 - 2022/06 Cyclodextrins associated to polymeric nanovaccines for immune cell targeting
Coorientador
2022/02/01 - 2022/06 Cyclodextrins associated nanocarriers for immune modulation.
Coorientador
2022/02/01 - 2022/06 Nanovaccines for immune modulation in pancreatic cancer
Coorientador
Univerza v Ljubljani, Eslovénia
2021/09/01 - 2022 Impact of microbiome in cancer nano-immunotherapy
Orientador
2021/09/01 - 2022 PLGA in situ forming microparticles loaded with nanosized dexamethasone as long-term drug delivery carriers
Orientador
2020/09/01 - 2021/12 Combination of a multifunctional nanovaccine with modulators of pancreatic cancer microenvironment
Coorientador
 M.Sc. in BioPharmaceutical Sciences (FFUL) (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/01 - 2021/04 Nanovaccines for immune modulation in pancreatic cancer
Coorientador
2021 - 2021 Recent nanotechnological approaches for immunotherapy in type 1 diabetes
Orientador
 Master Thesis in Pharmaceutical Sciences at FFUL (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 Impact of microbiome in cancer nano-immunotherapy
Orientador
 Master Thesis in Pharmaceutical Sciences at FFUL (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Detection of mannose moieties on the surface of nanoparticle-based immunotherapy
Coorientador
 Biologia Celular e Molecular (Licenciatura/Bacharelato)
Universidade Nova de Lisboa, Portugal
2020 - 2021 Development of PCL-based nanovaccine for DC-targeting
Orientador
2020 - 2021 PCL-based nanovaccines for pancreatic cancer
Coorientador
2019/10 - 2020/09 Nanoplatform to modulate dendritic cells and tumor microenvironment against Triple negative breast cancer
Coorientador
 Master Thesis in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/12 Nanovaccines as tumor microenvironment modulators
Coorientador
 Thesis (2nd semester) in Pharmaceutical Sciences(FFUL) (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12 Multi-functional nanovaccine modulates dendritic cell effector function against melanoma
Coorientador
 Master Thesis in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12 Impact of the modulation of tumor vasculature on cancer vaccine efficacy against colorectal cancer
Coorientador
 Master Thesis in Biopharmaceutical Sciences (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/07 Development of polysaccharide-based biodegradable nanovaccines for dendritic cell targeting
Coorientador
 Project II (2nd semester) Pharmaceutical Sciences(FFUL) (Outra)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02 Optimization of Dendritic Cell- targeting nanovaccines
Coorientador
 Project III (1st semester) Pharmaceutical Sciences(FFUL) (Outra)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02 Optimization of polymeric based-nanovaccines for dendritic cell targeting
Coorientador
 Project I (1st semester) Pharmaceutical Sciences(FFUL) (Outra)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09 - 2018/02 Combination of ß-glucan and mannose as immunomodulators in a multicomponent nanoscale therapeutic cancer vaccine
Coorientador
 Project I (1st semester) Pharmaceutical Sciences(FFUL) (Outra)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/01/23 - 2019/01/23 2nd SPLC-CRS Young Scientist Meeting (2019/01/23 - 2019/01/23)
Conferência (Membro da Comissão Científica)
2012/12/19 - 2012/12/19 IX Annual Meeting of Center for Neuroscience and Cell Biology (2012 - 2012)
Encontro (Membro da Comissão Organizadora)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2018/07/10 - 2018/07/12 Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain
Oficina (workshop)
2017/10/04 - 2017/10/06 Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland
Oficina (workshop)
2017/01/17 - 2017/01/19 Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”, Eindhoven, Netherlands
Oficina (workshop)
2011/11/14 - 2011/11/18 Course of “International de la Red Iberoamericana de Nuevos Materiales para el Diseño de Sistemas Avanzados de Liberación de Fármacos en Enfermedades de Alto Impacto Socioeconómico (RIMADEL)”, Santiago de Compostela, Spain
Oficina (workshop)
2011/02/28 - 2011/03/04 Course of “Fluorescence/ Confocal Microscopy and Flow Cytometry – An integrative approach to cell analysis”, Braga, Portugal
Oficina (workshop)
2010/04/19 - 2010/04/30 Course of “Laboratory Animal Science - Category C”, accredited by FELASA, Coimbra, Portugal
2009/03/09 - 2009/03/13 Course of “Obesity and Type II Diabetes”, Coimbra, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/12/15 Characterization of breast cancer immunity
Arguente
 Raquel Ventura Rebordão Gouveia (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12 Alginate Rubber Mask as a Double Friend: Cosmetic and Skin Barrier Protector
Arguente principal
 Maria Rita Ramos Curva (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/20 Formulation and characterization of drug-loaded PLGA nanoparticles Imaging capabilities of Raman-bas
Arguente principal
 Teresa Ramires Ruas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/15 Formulações Lipossomais de Glucocorticóides para o tratamento da Artrite Reumatóide: Preparação, caracterização e avaliação in vitro.
Arguente principal
 Tatiana Filipa Rebelo Pereira (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11/18 Evaluation of neuron/glia network signals using 2D/3D platforms and ALS experimental models
Arguente
 Beatriz da Cunha Suyumov (Mestrado)
2022/11/16 Investigation of a correlation between the stability of polymeric NPs towards temperature and gene knockdown efficiency
Arguente principal
 Daniela Azedo (Mestrado)
2022/07/22 Pancreatic Ductal Adenocarcinoma (PDAC): Modulation of Cathepsin S
Arguente
 Ana Marta Reinold´s Nunes (Outro)

Arbitragem científica em conferência

Nome da conferência Local da conferência
2018/09 - 2020/08 SPLC-CRS Young Scientist Meeting

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021 - Atual Pharmaceutics

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2021 - Atual COST Association External Reviewer
Avaliador

Membro de associação

Nome da associação Tipo de participação
2018 - Atual Association for Cancer Immunotherapy (CIMT)
2016 - Atual European Association for Cancer Research (EACR)
2016 - Atual Portuguese Association for Cancer Research (ASPIC)
2015 - Atual The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)
2015 - Atual Portuguese Society of Biochemistry (SPB)
2015 - Atual Federation of European Biochemical Societies (FEBS)
2012 - 2013 Grupo de Investigação Fundamental e Translacional (GIFT)
2012 - 2013 Grupo de Estudos de Pé Diabético em Portugal (GREPED)
2009 - 2013 Portuguese Society of Diabetology (SPD)
2009 - 2013 European Association for the Study of Diabetes (EASD)

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2023/08 - Atual President of the Jury - call for the award of 1 (One) Master Research Grant within the scope of the project 2022.04506.PTDC, titled “Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático Reference: BICNCG/14/FARM-ID/2023 Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019 Jury of undergraduated student research project - Project II (2nd semester) Pharmaceutical Sciences(FFUL) Universidade de Lisboa Faculdade de Farmácia, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2024 - Atual Genes
2024 - Atual Cells
2024 - Atual Biochimica et Biophysica Acta
2022 - Atual Viruses
2021 - Atual Materials Today Bio
2021 - Atual Vaccines
2020 - Atual DDTR
2020 - Atual Pharmaceutics

Tutoria

Tópico Nome do aluno
2023/07/01 - 2023/07/06 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO Célia Borges
2023/07 - 2023/07 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro” Katarina Coelho
2023/07 - 2023/07 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro” Luana Favaro
2022/06/27 - 2022/07/01 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório Letícia Soares Barcelos
2022/06/27 - 2022/07/01 OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório João Carneiro
2011/02 - 2012/02 A cicatrização de feridas está comprometida durante a fase inicial de cura em ratinhos Balb/c/Rag2-/-IL2R-/- Jenifer Gonçalves
2010/09 - 2011/04 Role of neurotensin in diabetic wound healing Valentina Maio
2009/10 - 2010/07 Neurotensin effect on skin dendritic cells and fibroblasts: repercussions in wound healing and diabetic wound healing Lucilia Pereira da Silva
Distinções

Prémio

2022 ERASMUS + - mobility grant, for 13th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
2011 Bolsa Dr. M. M. Almeida Ruas - S.P.D. / Novo Nordisk - "Promoting endothelial progenitor cell function in diabetic wound healing"
Sociedade Portuguesa de Diabetologia, Portugal

Outra distinção

2020 Topic Editor - Journal Pharmaceutics
2019 Travel Grant fellowship for 17th CIMT Annual Meeting; Mainz, Germany, 21st – 23rd May 2019
2018 Grant by Cost Action for Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain, 10th-12th July 2018
2018 Travel Grant fellowship for 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. Valencia, Spain; 28th-30th May 2018
2017 Grant by Cost Action for Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland, 4th-6th October 2017
2017 FEBS Bursary for 42nd FEBS Congress; Jerusalem, 10-14 September 2017
2017 Grant by Cost Action for Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”; Eindhoven, Netherlands, 17th-19th January 2017
2016 Travel Grant fellowship for 16th YSF and 41st FEBS Congress; Kusadasi, Turkey; 30 August - 9 September 2016
2014 Post-Doctoral fellowship reference SFRH/BPD/94111/2013 from the Portuguese Foundation for Science and Technology (FCT)
Fundação para a Ciência e a Tecnologia, Portugal
2014 Post-Doctoral fellowship funded by the European project Ref: REGPOT-CT2012-316331-POLARIS
Biomaterials Biodegradables and Biomimetics, Portugal
2012 Travel grant fellowship for 48th EASD Annual Meeting; Berlim; Germany; 1st-5th October 2012
2009 PhD Fellowship reference SFRH/BD/60837/2009 from the Portuguese Foundation for Science and Technology (FCT)
Fundação para a Ciência e a Tecnologia, Portugal
2009 Graduate Research fellowship funded by the FCT project Ref: POCI/SAU-MMO/57598/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008 Grant by IBeSa to attend XVI National Congress of Biochemistry, Ponta Delgada, Portugal, 22th – 25th October 2008