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In September of 2018, I completed my PhD in Biochemistry at University of Aveiro (UA). My PhD was supported by a Grant from an European Research Council (ERC) project intitled: "IgY Technology: A Purification Platform using Ionic-Liquid-Based Aqueous Biphasic Systems". During my PhD, from January 2015 to March 2015, I was a trainee at Institut National des Sciences Appliquées de Lyon, France. From October 2018 to March 2019, I was a post-doctoral researcher involved in the same International Project from the ERC, at UA, now focused on the developed technologies scale-up. In October of 2018, I was a visiting researcher at Université de Reims Champagne Ardenne - Institut de Chimie Moléculaire de Reims, France, working on ionic liquids synthesis. From April 2019 to January 2022, I was a researcher involved in the development of new platforms for the purification of L-Asparaginase, an antileukemic biopharmaceutical of current high-cost. In June 2019, I was a visiting researcher at Université de Reims Champagne Ardenne, and from October to November 20219, I was a visiting researcher in School of Pharmaceutical Sciences, UNESP, Araraquara, Brazil. Since February 2022 I'm a researcher in ITQB-NOVA focused on heme homeostasis in human pathogens, namely on the enzymes involved in heme biosynthesis and acquisition pathways. Since 2014, I published 30 articles in international peer reviewed journals and 6 book chapters, demonstrating my commitment to science. Besides my publications, during my PhD an efficient technology to purify Immunoglobulin Y (IgY) was developed and an international patent (WO 2020/058937 A1) application was filled. With the aim to promote my research work over the world, I participated in several national/international meetings. During the past years, I was the supervisor of 9 BSc final projects and co-supervisor of 4 MSc theses, and collaborated in the supervision of 4 MSc theses and 1 BSc final project.
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Identificação

Identificação pessoal

Nome completo
Ana Mafalda Rodrigues Almeida Rocha

Nomes de citação

  • Mafalda R. Almeida

Identificadores de autor

Ciência ID
8E16-D486-1960
ORCID iD
0000-0003-2101-8309
Scopus Author Id
56096309900

Endereços de correio eletrónico

  • mafalda.almeida90@gmail.com (Pessoal)

Telefones

Telemóvel
  • 911885716 (Pessoal)

Moradas

  • ITQB-NOVA, 2780-157, Oeiras, Oeiras, Portugal (Profissional)
  • Rua Prof. António Rainho, nº1, 1ºEsq., 2500-118, Caldas da Rainha, Caldas da Rainha, Portugal (Pessoal)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Microbiologia
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1)
Português (Idioma materno)
Formação
Grau Classificação
2018/10 - 2019/03
Concluído
 Research fellow (Pós-doutoramento)
Universidade de Aveiro, Portugal
2014/02/01 - 2018/09/21
Concluído
 Bioquímica (Doutoramento)
Especialização em Sem especialidade
Universidade de Aveiro, Portugal
"Development of purification platforms for Immunoglobulin Y using aqueous biphasic systems" (TESE/DISSERTAÇÃO)
2017/02 - 2017/07
Concluído
 COHiTEC Program (Outros)
Universidade do Porto Porto Business School, Portugal
2015/01/08 - 2015/03/30
Concluído
 Centrifugal partition chromatography course (Outros)
Institut des Sciences Analytiques, França
2011 - 2013/07/11
Concluído
 Bioquímica (Mestrado)
Especialização em Área de especialização: Métodos Biomoleculares
Universidade de Aveiro, Portugal
"Purification of antibodies using aqueous-two phase systems" (TESE/DISSERTAÇÃO)
2008 - 2011/09
Concluído
 Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/02/23 - Atual Investigador (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/04/01 - 2022/01/31 Investigador (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
2019/10/22 - 2019/11/21 Investigador visitante (Investigação) Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brasil
Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brasil
2019/06/18 - 2019/06/27 Investigador visitante (Investigação) Institut de Chimie Moléculaire de Reims, França
Institut de Chimie Moléculaire de Reims, França
2018/10 - 2019/03 Pós-doutorado (Investigação) Universidade de Aveiro CICECO, Portugal
2018/10/09 - 2018/10/19 Investigador visitante (Investigação) Institut de Chimie Moléculaire de Reims, França
Institut de Chimie Moléculaire de Reims, França
2014/02/01 - 2018/09/21 Estagiário de Investigação (Investigação) Universidade de Aveiro CICECO, Portugal
2015/01 - 2015/03 Investigador visitante (Investigação) Institut National des Sciences Appliquées de Lyon, França
Projetos

Bolsa

Designação Financiadores
2014/02/01 - 2018/09/20 IgY technology: a purification platform using ionic-liquid-based aqueous biphasic systems
ECR-2013-StG-337753
Bolseiro de Doutoramento
Universidade de Aveiro CICECO, Portugal
 European Research Council
Concluído

Projeto

Designação Financiadores
2022/10/01 - Atual Interaction of RIC with iron-sulfur biogenesis systems
PTDC/BIA-MIC/0268/2021
Investigador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Em curso
2022/02/23 - 2022/09/30 Diversity and complexity of microbial multidomain oxygen and/or nitric oxide reductases flavodiiron enzymes from Clostridiales
PTDC/BIA-BQM/27959/2017
Investigador
Concluído
2019/04/01 - 2022/01/31 Development of sustainable nanomaterials for the purification of antileukemic drugs
POCI-01-0145-FEDER-031268
Investigador
Universidade de Aveiro, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal

Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brasil
Fundação para a Ciência e a Tecnologia
Concluído

Outro

Designação Financiadores
2018/06 - 2019/12/31 Extraction and purification of RuBisCo: from waste product to high-value functional protein
4318/40851YL
Investigador
Universidade de Aveiro CICECO, Portugal

Institut de Chimie Moléculaire de Reims, França
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em boletim informativo
  1. Mafalda R. Almeida. "Publication | Purification of green fluorescent protein using fast centrifugal partition chromatography", UAveiro Research, 2021, https://mailchi.mp/7524680bc85a/uaveiro-research-newsletter-234?e=1ea214807b.
  2. Mafalda R. Almeida. "Publication | Recovery of immunoglobulin G from rabbit serum using k-carrageenan-modified hybrid magnetic nanoparticles", UAveiro Research, 2020, https://mailchi.mp/a575adaa7157/uaveiro-research-newsletter-199?e=1ea214807b.
  3. Mafalda R. Almeida. "Publication | Improvements in the enzymatic degradation of textile dyes using ionic-liquid-based surfactants", UAveiro Research, 2020, https://mailchi.mp/035941664835/uaveiro-research-newsletter-193?e=ccad0147cd.
Artigo em revista
  1. Jordi Zamarreno Beas; Marco A. M. Videira, ; Val Karavaeva; Frederico M. Lourenço; Mafalda R. Almeida; Filipa Sousa; Lígia M. Saraiva. "In Campylobacter jejuni, a new type of chaperone receives heme from ferrochelatase". Frontiers in Genetics 14 (2023): http://dx.doi.org/10.3389/fgene.2023.1199357.
    10.3389/fgene.2023.1199357
  2. João C. F. Nunes; Mafalda R. Almeida; Gabriela B. de Paiva; Danielle B. Pedrolli; Valéria C. Ebinuma-Santos; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "A flow-through strategy using supported ionic liquids for L-asparaginase purification". Separation and Purification Technology 315 (2023): 123718. http://dx.doi.org/10.1016/j.seppur.2023.123718.
    No prelo • 10.1016/j.seppur.2023.123718
  3. Liliana S O Silva; Frederico M. Lourenço; Mafalda R. Almeida; Saraiva, Ligia M. "Structural Basis of Escherichia coli YtfE Iron Donor Properties". Encyclopedia of Inorganic and Bioinorganic Chemistry (2023):
    Publicado
  4. Marguerita E. Rosa; Ana M. Ferreira; Catarina M. S. S. Neves; Mafalda R. Almeida; Rafael Barros; Ana C. Cristóvão; Ana C. A. Sousa; et al. "Valorisation of red beet waste: one-step extraction and separation of betalains and chlorophylls using thermoreversible aqueous biphasic systems". Green Chemistry 25 5 (2023): 1852-1864. http://dx.doi.org/10.1039/d2gc04480c.
    Publicado • 10.1039/d2gc04480c
  5. Mafalda R. Almeida; Rita A. M. Barros; Matheus M. Pereira; Daniel Castro; Joaquim L. Faria; Mara G. Freire; Cláudia G. Silva; Ana P.M.Tavares. "Multi-walled carbon nanotubes as a platform for Immunoglobulin G attachment". Chemical Engineering and Processing - Process Intensification 183 (2023): 109214. http://dx.doi.org/10.1016/j.cep.2022.109214.
    10.1016/j.cep.2022.109214
  6. Bojan Kopilovic; Ana I. Valente; Ana M. Ferreira; Mafalda R. Almeida; Ana P. M. Tavares; Mara G. Freire; Joao A. P. Coutinho. "Towards the sustainable extraction and purification of non-animal proteins from biomass using alternative solvents". RSC Sustainability 1 6 (2023): 1314-1331. http://dx.doi.org/10.1039/d3su00062a.
    10.1039/d3su00062a
  7. Mafalda R. Almeida; Filipe Ferreira; Pedro Domingues; João A. P. Coutinho; Mara G. Freire. "Towards the purification of IgY from egg yolk by centrifugal partition chromatography". Separation and Purification Technology 299 (2022): 121697. http://dx.doi.org/10.1016/j.seppur.2022.121697.
    10.1016/j.seppur.2022.121697
  8. Heitor B. S. Bento; Gabriela B. Paiva; Mafalda R. Almeida; Cláudia G. Silva; Pedro J. Carvalho; Ana P. M. Tavares; Danielle B. Pedrolli; Valéria C. Ebinuma-Santos. "Aliivibrio fischeri L-asparaginase production by engineered Bacillus subtilis: a potential new biopharmaceutical". Bioprocess and Biosystems Engineering 45 10 (2022): 1635-1644. http://dx.doi.org/10.1007/s00449-022-02769-x.
    10.1007/s00449-022-02769-x
  9. Mafalda R. Almeida; Ana F.C.S. Rufino; Diana C.V. Belchior; Pedro J. Carvalho; Mara G. Freire. "Characterization of cholinium-carboxylate-based aqueous biphasic systems". Fluid Phase Equilibria 558 (2022): 113458. http://dx.doi.org/10.1016/j.fluid.2022.113458.
    10.1016/j.fluid.2022.113458
  10. João C. F. Nunes; Mafalda R. Almeida; Rui M. F. Bento; Matheus M. Pereira; Valéria C. Santos-Ebinuma; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Enhanced enzyme reuse through the bioconjugation of L-asparaginase and silica-based supported ionic liquid-like phase materials". Molecules 27 3 (2022): 929. http://dx.doi.org/10.3390/molecules27030929.
    10.3390/molecules27030929
  11. Ana F. C. S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P. Coutinho; Mara G. Freire. "Separation of albumin from bovine serum applying ionic-liquid-based aqueous biphasic systems". Applied Sciences 12 2 (2022): 707. http://dx.doi.org/10.3390/app12020707.
    10.3390/app12020707
  12. Ana I. Valente; Ana M. Ferreira; Mafalda R. Almeida; Aminou Mohamadou; Mara G. Freire; Ana P. M. Tavares. Autor correspondente: Ana P. M. Tavares. "Efficient extraction of the RuBisCO enzyme from spinach leaves using aqueous solutions of biocompatible ionic liquids". Sustainable Chemistry 3 1 (2021): 1-18. http://dx.doi.org/10.3390/suschem3010001.
    10.3390/suschem3010001
  13. Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Rui A. R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. Autor correspondente: Cláudia G. Silva. "Superior operational stability of immobilized l-asparaginase over surface-modified carbon nanotubes". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-00841-2.
    Publicado • 10.1038/s41598-021-00841-2
  14. Castro, Daniel; Marques, Ana Sofia C.; Almeida, Mafalda R.; de Paiva, Gabriela B.; Bento, Heitor B. S.; Pedrolli, Danielle B.; Freire, Mara G.; Tavares, Ana P. M.; Santos-Ebinuma, Valéria C.. "L-asparaginase production review: bioprocess design and biochemical characteristics". Applied Microbiology and Biotechnology 105 11 (2021): 4515-4534. http://dx.doi.org/10.1007/s00253-021-11359-y.
    10.1007/s00253-021-11359-y
  15. João C. F. Nunes; Mafalda R. Almeida; Joaquim L. Faria; Cláudia G. Silva; Neves, Márcia C.; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Overview on protein extraction and purification using ionic-liquid-based processes". Journal of Solution Chemistry (2021): http://dx.doi.org/10.1007/s10953-021-01062-x.
    10.1007/s10953-021-01062-x
  16. Álvaro Silva Lima; Bruno Sales de Oliveira; Selesa Vanessa Shabudin; Mafalda R. Almeida; Mara G. Freire; Katharina Bica. "Purification of anthocyanins from grape pomace by centrifugal partition chromatography". Journal of Molecular Liquids 326 (2021): 115324. http://dx.doi.org/10.1016/j.molliq.2021.115324.
    10.1016/j.molliq.2021.115324
  17. Bruna P. Soares; João H.P.M. Santos; Margarida Martins; Mafalda R. Almeida; Nathalia V. Santos; Mara G. Freire; Valéria C. Santos-Ebinuma; et al. "Purification of green fluorescent protein using fast centrifugal partition chromatography". Separation and Purification Technology 257 (2021): 117648. http://dx.doi.org/10.1016/j.seppur.2020.117648.
    10.1016/j.seppur.2020.117648
  18. Ana R.F. Carreira; Ana M. Ferreira; Mafalda R. Almeida; João A.P. Coutinho; Tânia E. Sintra. "Propranolol resolution using enantioselective biphasic systems". Separation and Purification Technology 254 (2021): 117682. http://dx.doi.org/10.1016/j.seppur.2020.117682.
    10.1016/j.seppur.2020.117682
  19. Daniela Millan; Mafalda R. Almeida; Ana Filipa Rufino; Joao A. P. Coutinho; Mara G. Freire. "Nucleophilic degradation of Diazinon in thermoreversible polymer-polymer aqueous biphasic systems". Physical Chemistry Chemical Physics (2021): http://dx.doi.org/10.1039/d0cp06086k.
    10.1039/d0cp06086k
  20. Raquel O. Cristóvão; Mafalda R. Almeida; Maria A. Barros; João C. F. Nunes (FA1D-F3E2-FBA8); Rui A.R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. "Development and characterization of a novel l-asparaginase/MWCNT nanobioconjugate". RSC Advances 10 52 (2020): 31205-31213. http://dx.doi.org/10.1039/d0ra05534d.
    10.1039/d0ra05534d
  21. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Maria C. Gomes; João F. Mano; et al. "Instantaneous fibrillation of egg white proteome with ionic liquid and macromolecular crowding". Communications Materials 1 1 (2020): http://dx.doi.org/10.1038/s43246-020-0035-0.
    10.1038/s43246-020-0035-0
  22. Aleksandra Dimitrijevic; Ana P. M. Tavares (2A10-5072-A254); Mafalda R. Almeida; Milan Vrane; Ana C. A. Sousa; Ana C. Cristóvão; Tatjana Trtic-Petrovic; Slobodan Gad¿uric; Mara G. Freire. "Valorization of expired energy drinks by designed and integrated ionic liquid-based aqueous biphasic systems". ACS Sustainable Chemistry & Engineering 8 14 (2020): 5683-5692. http://dx.doi.org/10.1021/acssuschemeng.0c00429.
    10.1021/acssuschemeng.0c00429
  23. Rui M. F. Bento; Mafalda R. Almeida; Pankaj Bharmoria; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Improvements in the enzymatic degradation of textile dyes using ionic-liquid-based surfactants". Separation and Purification Technology 235 (2020): 116191. http://dx.doi.org/10.1016/j.seppur.2019.116191.
    10.1016/j.seppur.2019.116191
  24. Flávia F. Magalhães; Mafalda R. Almeida; Sofia F. Soares (6D19-4755-BF06); Tito Trindade; Mara G. Freire; Ana Luísa Daniel-da-Silva; Ana P. M. Tavares (2A10-5072-A254). "Recovery of immunoglobulin G from rabbit serum using ¿-carrageenan-modified hybrid magnetic nanoparticles". International Journal of Biological Macromolecules (2020): http://dx.doi.org/10.1016/j.ijbiomac.2020.02.135.
    Publicado • 10.1016/j.ijbiomac.2020.02.135
  25. Mafalda R. Almeida; Diana C. V. Belchior; Pedro J. Carvalho; Mara G. Freire. "Liquid-liquid equilibrium and extraction performance of aqueous biphasic systems composed of water, cholinium carboxylate ionic liquids and K2CO3". Journal of Chemical & Engineering Data (2019): http://dx.doi.org/10.1021/acs.jced.9b00452.
    Publicado • 10.1021/acs.jced.9b00452
  26. Diana C. V. Belchior; Mafalda R. Almeida; Tânia E. Sintra; Sónia P. M. Ventura; Iola F. Duarte; Mara G. Freire. "Odd-even effect in the formation and extraction performance of ionic-liquid-based aqueous biphasic systems". Industrial & Engineering Chemistry Research (2019): http://dx.doi.org/10.1021/acs.iecr.9b00663.
    Publicado • 10.1021/acs.iecr.9b00663
  27. João H. P. M. Santos; Ana M. Ferreira; Mafalda R. Almeida; Paula S. G. N. Quinteiro; Ana C. R. V. Dias; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire; Carlota O. Rangel-Yagui; Sónia P. M. Ventura. "Continuous separation of cytochrome-c PEGylated conjugates by fast centrifugal partition chromatography". Green Chemistry (2019): http://dx.doi.org/10.1039/c9gc01063g.
    Publicado • 10.1039/c9gc01063g
  28. João H. P. M. Santos; Mafalda R. Almeida; Cáudia I. R. Martins; Ana C. R. V. Dias; Mara G. Freire; Joao A. P. Coutinho; Sónia P. M. Ventura. "Separation of phenolic compounds by centrifugal partition chromatography". Green Chemistry 20 8 (2018): 1906-1916. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045949682&partnerID=MN8TOARS.
    Publicado • 10.1039/c8gc00179k
  29. Matheus M. Pereira; Mafalda R. Almeida; Joana M. Gomes; Ana F. C. S. Rufino; Marguerita E. Rosa; Joao A. P. Coutinho (8B1B-C80E-3C50); Aminou Mohamadou; Mara G. Freire. "Glycine-betaine ionic liquid analogues as novel phase-forming components of aqueous biphasic systems". Biotechnology Progress 34 5 (2018): 1205-1212. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053194986&partnerID=MN8TOARS.
    Publicado • 10.1002/btpr.2685
  30. Matheus M. Pereira; Rafaela A. P. Cruz; Mafalda R. Almeida; Álvaro S. Lima; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Single-step purification of ovalbumin from egg white using aqueous biphasic systems". Process Biochemistry 51 6 (2016): 781-791. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978321056&partnerID=MN8TOARS.
    Publicado • 10.1016/j.procbio.2016.03.002
  31. Mohamed Taha; Mafalda R. Almeida; Francica A. e Silva; Pedro Domingues; Sónia P. M. Ventura; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Novel biocompatible and self-buffering ionic liquids for biopharmaceutical applications". Chemistry - A European Journal 21 12 (2015): 4781-4788. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924062386&partnerID=MN8TOARS.
    Publicado • 10.1002/chem.201405693
  32. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire. "Ionic liquids as additives to enhance the extraction of antioxidants in aqueous two-phase systems". Separation and Purification Technology 128 (2014): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897480798&partnerID=MN8TOARS.
    Publicado • 10.1016/j.seppur.2014.03.004
Capítulo de livro
  1. João C. F. Nunes; Flávia F. Magalhães; Marília T. Araújo; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares. "Expansion of targeted drug-delivery systems using microbially sources biosurfactant". In Green Sustainable Process for Chemical and Environmental Engineering and Science, editado por Mohd Imran Ahamed; Charles Adetunji, 105-120. Elsevier, 2022.
    Publicado • 10.1016/b978-0-323-85146-6.00034-6
  2. Mafalda R. Almeida; João C. F. Nunes; Raquel O. Cristóvão; Joaquim L. Faria; Ana P. M. Tavares; Cláudia G. Silva; Mara G. Freire. "Carbon nanotubes for biomedical applications". In Materials Horizons: From Nature to Nanomaterials, 285-331. Springer Singapore, 2022.
    Publicado • 10.1007/978-981-16-7483-9_14
  3. Flávia F. Magalhães; João C. F. Nunes (FA1D-F3E2-FBA8); Marília T. Araújo; Ana M. Ferreira; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Anti-cancer biosurfactants". In Microbial Biosurfactants: Preparation, Properties and Applications. Springer, 2021.
    Publicado • 10.1007/978-981-15-6607-3
  4. Mafalda R. Almeida; Márcia C. Neves; Sérgio Morales-Torres; Mara G. Freire; Joaquim L. Faria; Valéria C. Santos-Ebinuma; Cláudia G. Silva; Ana P. M. Tavares. "Biomedical related applications of functionalized nanomaterials". In Handbook of Functionalized Nanomaterials for Industrial Applications, editado por Chaudhery Mustansar Hussain. Elsevier, 2020.
    Publicado
  5. Mafalda R. Almeida; Ana M. Ferreira; João C. F. Nunes (FA1D-F3E2-FBA8); Ana P. M. Tavares (2A10-5072-A254). "Purification, characterization and clinical applications of therapeutic enzymes". In Research Advances in the Fungal World: Culture, Isolation, Identification, Classification, Characterization, Properties and Kinetics. Nova Science Publishers, 2020.
    Publicado
  6. Maria V. Quental; Mafalda R. Almeida; Joana Gomes; Judite Resende; Pedro Domingues; Mara G. Freire. "Imunoglobulina Y (IgY): uma alternativa promissora aos anticorpos de mamíferos". In Bioquímica e Bem-Estar, editado por Manuel António Coimbra. Portugal, 2017.
    Publicado
Entrada de enciclopédia
  1. Liliana S. Silva; Frederico M. Lourenço; Mafalda R. Almeida; Lígia M. Saraiva. "Structural Basis of Escherichia coli YtfE Iron Donor Properties". In Encyclopedia of Inorganic and Bioinorganic Chemistry, 2023.
    Publicado
Poster em conferência
  1. Jordi Zamarreno Beas; Mafalda R. Almeida; Marco A. M. Videira; Val Karavaeva; Frederico M. Lourenço; Filipa Sousa; Lígia Saraiva. "Revealing heme b biosynthesis pathway in Campylobacter jejuni". Trabalho apresentado em Tetrapyrrole discussion group meeting, 2023.
  2. Ana F.C.S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P. Coutinho; Mara G. Freire. "Ionic liquid-based aqueous biphasic systems for extraction and purification of albumin from bovine serum". Trabalho apresentado em Jornadas CICECO 2022, 2022.
  3. Ana F.C.S Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P Coutinho; Mara G. Freire. "Separation of albumin from bovine serum applying ionic-liquid-based aqueous biphasic systems". Trabalho apresentado em BPP 2022, Biopartitiong & Purification Conference, 2022.
  4. João A. P. Coutinho; Mafalda R. Almeida; Filipe Ferreira; Pedro Domingues; Mara G. Freire. "Towards the purification of IgY from egg yolk by centrifugal partition chromatography". Trabalho apresentado em ISEC 2022, International solvent extraction conference, 2022.
  5. Mafalda R. Almeida; Bruno A. Salgueiro; Filipe Folgosa; Miguel Teixeira. "Characterization of Pseudogulbenkiana ferrooxidans and Photobacterium swingsii flavorubredoxins". Trabalho apresentado em Final Annual Meeting, Twin to illuminate metal in biology and biocatalysis through biospectroscopy, TIMB3, 2022.
  6. Ana P. M. Tavares (2A10-5072-A254); Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Joaquim L. Faria; Márcia C. Neves; et al. "Immobilization of L-asparaginase towards surface-modified carbon nanotubes". Trabalho apresentado em ISPPP 2021, 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides, 2021.
  7. João C. F. Nunes; Mafalda R. Almeida; Valéria C. Santos-Ebinuma; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "Sustainable lysis of Bacillus subtilis biomass to recover the biopharmaceutical L-asparaginase". Trabalho apresentado em MICROBIOTEC 21, Congress of Microbiology and Biotechnology 2021, 2021.
  8. Mafalda R. Almeida; Ana I. Valente; Ana M. Ferreira; Mara G. Freire; Ana P. M. Taes. "Extraction and purification of RuBisCO from residual biomass". Trabalho apresentado em RRB 2021, Renewable Resources & Biorefeneries Confererence, 2021.
  9. Ana F.C.S. Rufino; Mafalda R. Almeida; Mukesh Sharma; João A. P Coutinho; Mara G. Freire. "Ionic liquid-based aqueous biphasic systems for the pre-purification of bovine serum albumin". Trabalho apresentado em DCE 2021, Doctoral Congress in Engineering, 2021.
  10. Mafalda R. Almeida; Raquel O. Cristóvão; Maria A. Barros; João C. F. Nunes; Rui A.R. Boaventura; José M. Loureiro; Joaquim L. Faria; et al. "Immobilization of L-asparaginase towards surface-modified carbon nanotubes". Trabalho apresentado em Affinity 2021, 2021.
  11. Ana I. Valente; Ana M. Ferreira; Mara G. Freire; Mafalda R. Almeida; Aminou Mohamadou; Ana P. M. Tavares (2A10-5072-A254). "RuBisCOs' extraction and purification: from residual biomass to a value-added enzyme". Trabalho apresentado em Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  12. Daniel F. Castro; Valéria C. Santos-Ebinuma; Mara G. Freire; Mafalda R. Almeida; Ana P. M. Tavares (2A10-5072-A254). "Optimization of L-asparaginase production by Bacillus Subtilis". Trabalho apresentado em Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  13. Ana R. F. Carreira; Ana M. Ferreira; Mafalda R. Almeida; Joao A. P. Coutinho (8B1B-C80E-3C50); Tânia E. Sintra. "A selective journey: enantioselective biphasic systems for the resolution of propranolol". Trabalho apresentado em Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  14. João C. F. Nunes (FA1D-F3E2-FBA8); Rui M. F. Bento; Mafalda R. Almeida; Márcia C. Neves; Valéria C. Santos-Ebinuma; Ana P. M. Tavares (2A10-5072-A254); Mara G. Freire. "Improved immobilization of L-asparaginase on silica-based supported ionic liquids". Trabalho apresentado em Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  15. Rui M. F. Bento; Mafalda R. Almeida; Márcia C. Neves; Valéria C. Santos-Ebinuma; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Enzyme adsorption on modified silica carriers". Trabalho apresentado em Jornadas CICECO 2020 - THE FUTURE OF SCIENCE AND CICECO: what have we learned from the pandemic?, 2020.
  16. João C. F. Nunes (FA1D-F3E2-FBA8); Raquel O. Cristóvão; M. Amélia Barros; Mafalda R. Almeida; Joaquim L. Faria; Maria J. Sampaio; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254); Cláudia G. Silva. "Using carbon nanotubes for antileukemic drugs purification". Trabalho apresentado em Microbiotec'19, 2019.
  17. João C. F. Nunes (FA1D-F3E2-FBA8); Margarida Rosmaninho; Margarida C. Ribeiro; Mafalda R. Almeida; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Extraction of L-asparaginase through supported ionic liquid materials based on silica". Trabalho apresentado em Microbiotec'19, 2019.
  18. Rui M. F. Bento; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Decolorization of dyes from textile effluents by laccase using ionic liquids". Trabalho apresentado em XXV Encontro Galego Portugués de Química, 2019.
  19. Sónia P. M. Ventura; João H. P. M. Santos; Mafalda R. Almeida; Ana C. R. V. Dias; Mara G. Freire; Joao A. P. Coutinho (8B1B-C80E-3C50). "Up-scale fractionation of phenolic compounds using centrifugal partition chromatography". Trabalho apresentado em ECAB5, 5th European Congress of Applied Biotechnology, 2019.
  20. Mafalda R. Almeida; Nunes, João C. F.; Raquel O. Cristóvão; M. Amélia Barros; Mara G. Freire; Valéria C. Santos-Ebinuma; Cláudia G. Silva; Ana P. M. Tavares. "Purification of antileukemic drugs using functionalized nanomaterials". Trabalho apresentado em BPP 22019, Bipartitiong & Purification Conference, 2019.
  21. Márcia C. Neves; Rui Bento; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Micelar ionic liquid-based micellar systems in an integrated platform for the removal of indigo". Trabalho apresentado em RICI 8, 8th Iberian Meeting on Colloids and Interfaces, 2019.
  22. Mafalda R. Almeida; Leonor S. Castro; Patrícia Pereira; Luís Passarinha; Fani Sousa; Joao A. P. Coutinho (8B1B-C80E-3C50); Ana P. M. Tavares (2A10-5072-A254); Mara G. Freire; Augusto Q. Pedro. "Aqueous two-phase systems comprising ionic liquids for the extraction of recombinant proteins". Trabalho apresentado em XIV Annual CICS-UBI Symposium (Universidade da Beira Interior), 2019.
  23. Mafalda R. Almeida; Sandra C. Bernardo; Ana Isabel Valente; Mara G. Freire; Aminou Mohamadou; Ana P. M. Tavares (2A10-5072-A254). "Extraction of RuBisCO through glycine-betaine ionic liquids-based aqueous biphasic systems". Trabalho apresentado em Jornadas CICECO 2019, 2019.
  24. Mafalda R. Almeida; Margarida F. C. Faria; Mara G. Freire; Luísa M. P. Martinez; Cláudia G. Silva; Ana P. M. Tavares (2A10-5072-A254). "Purification of human serum IgG with carbon nanomaterials". Trabalho apresentado em Jornadas CICECO 2019, 2019.
  25. João C. F. Nunes (FA1D-F3E2-FBA8); Mafalda R. Almeida; Margarida Rosmaninho; Margarida Ribeiro; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Antileukemic biopharmaceuticals purification using supported ionic liquid materials based on silica". Trabalho apresentado em Jornadas CICECO 2019, 2019.
  26. Rui M. F. Bento; Mafalda R. Almeida; Joao A. P. Coutinho (8B1B-C80E-3C50); Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Degradation of persistent pollutants using enzymatic micellar systems". Trabalho apresentado em Jornadas CICECO 2019, 2019.
  27. Leonor S. Castro; Mafalda R. Almeida; Patrícia Pereira; Luís Passarinha; Fani Sousa; Joao A. P. Coutinho (8B1B-C80E-3C50); Ana P. M. Tavares (2A10-5072-A254); Augusto Q. Pedro; Mara G. Freire. "Improving the purification of recombinant proteins by the use of ionic liquids as adjuvants in aqueous two-phase systems". Trabalho apresentado em Jornadas CICECO 2019, 2019.
  28. João C. F. Nunes; Mafalda R. Almeida; Margarida Rosmaninho; Margarida Ribeiro; Márcia C. Neves; Mara G. Freire; Ana P. M. Tavares. "Purification of antileukemic biopharmaceuticals using supported ionic liquid materials based on silica". Trabalho apresentado em 4th Meeting of Medicional Biotechnology, 2019.
  29. João C. F. Nunes; Margarida Rosmaninho; Margarida Ribeiro; Mafalda R. Almeida; Mara G. Freire; Ana P. M. Tavares (2A10-5072-A254). "Supported ionic liquid materials on silica for the purification of L-asparaginase". Trabalho apresentado em XII ENEBIOQ, XII Encontro Nacional de Estudantes de Bioquímica, 2019.
  30. Mara G. Freire; Mafalda R. Almeida; Ana Filipa M. Cláudio; Armando J. D. Silvestre; Erika S. Santos. "Salicornia crop in sustainable and highly saline agronomic systems as source of added-value compounds". Trabalho apresentado em 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences, 2018.
  31. João H. P. M. Santos; Mafalda R. Almeida; Cláudia Martins; Ana C. R. V. Dias; Mara G. Freire; João A. P. Coutinho; Sónia P. M. Ventura. "Fractionation of phenolic compounds derived from lignin depolymerization by centrifugal partition chromatography". Trabalho apresentado em 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences, 2018.
  32. Mafalda R. Almeida; Matheus M. Pereira; Joana Gomes; Ana F. C. S. Rufino; Marguerita E. Rosa; João A. P. Coutinho; Mara G. Freire. "Glycine-betaine ionic liquid analogues as novel phase-forming components of aqueous biphasic systems". Trabalho apresentado em Living science together, Jornadas CICECO 2018, 2018.
  33. Sónia P. M. Ventura; João H. P. M. Santos; Mafalda R. Almeida; Cláudia I. R. Martins; Ana C. R. V. Dias; Mara G. Freire; João A. P. Coutinho. "Centrifugal partition chromatography applied on the fractionation of phenolic compounds from lignin depolymerization". Trabalho apresentado em 2nd AGChem, 2nd Advances in Green Chemistry Conference, 2018.
  34. Mafalda R. Almeida; Judite Resende; Ana P. M. Tavares; Pedro Domingues; Mara G. Freire. "Aqueous biphasic systems (ABS) as an alternative platform to purify hen antibodies". Trabalho apresentado em ESIB2017, European Summit of Industrial Biotechnology 2017, 2017.
  35. João H. P. M. Santos; Cláudia Martins; Mafalda R. Almeida; Mara G. Freire; João A. P. Coutinho; Sónia P. M. Ventura. "Purification of phenolic compounds in continuous flow by centrifugal partition chromatography". Trabalho apresentado em BPP2017, Biopartitioning & Purification Conference 2017, 2017.
  36. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Igor Bdikin; João A. P. Coutinho; Mara G. Freire. "Growth of functional protein fibrils from egg white proteome: effect of protein crowding". Trabalho apresentado em II Jornadas Nacionais de Caracterização de Materiais, 2017.
  37. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk". Trabalho apresentado em ISPPP2016, International Symposium on the Separation of Proteins, Peptides and Polynucleotides 2016, 2016.
  38. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Platform for the purification of immunoglobulin Y (IgY) from egg yolk using aqueous biphasic systems". Trabalho apresentado em ESBES2016, European Symposium on Biochemical Engineering Sciences 2016, 2016.
  39. Pankaj Bharmoria; Dibyendu Mondal; Matheus M. Pereira; Márcia C. Neves; Mafalda R. Almeida; Mara G. Freire. "Growth of functional protein fibrils from egg white proteome: effect of protein crowding". Trabalho apresentado em Energy: trends and future chalenges, Jornadas CICECO 2016, 2016.
  40. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Purification of therapeutic immunoglobulin Y (IgY) from egg yolk using aqueous biphasic systems". Trabalho apresentado em IV ENEQUI, IV Encontro Nacional de Estudantes de Química, 2016.
  41. Emanuel V. Capela; Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Purification of immunoglobulin Y (IgY) using Aqueous Biphasic Systems". Trabalho apresentado em 2nd EuGSC, 2nd EuCheMS Congress on Green and Sustainable Chemistry, 2015.
  42. Mafalda R. Almeida; Maria V. Quental; Kiki A. Kurnia; João A. P. Coutinho; Mara G. Freire. "Extraction of IgY using a new category of aqueous biphasic systems composed of two ionic liquids". Trabalho apresentado em ECAB 3, 3rd European Congress of Applied Biotechnology, 2015.
  43. Maria V. Quental; Mafalda R. Almeida; Kiki A. Kurnia; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems composed of two ionic liquids as novel extraction platforms". Trabalho apresentado em IMIL15, Iberomerican Meeting on Ionic Liquids, 2015.
  44. Mafalda R. Almeida; Mohamed Taha; Francisca A. e Silva; Pedro Domingues; Sónia P. M. Ventura; João A. P. Coutinho; Mara G. Freire. "Novel biocompatible and self-buffering ionic liquids for biopharmaceutical applications". Trabalho apresentado em BPP 2015, Biopartitioning & Purification Conference 2015, 2015.
  45. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems with ionic liquids as additives to upgrade the extraction of three antioxidants". Trabalho apresentado em BPP 2015, Biopartitioning & Purification Conference 2015, 2015.
  46. Mafalda R. Almeida; Maria V. Quental; Mara G. Freire; João A. P. Coutinho. "Aqueous biphasic systems composed of two ionic liquids: a new plethora of separation platforms". Trabalho apresentado em Nineteenth Symposium on Thermophysical Properties, 2015.
  47. Joana Gomes; Judite Resende; Mafalda R. Almeida; Ana P. M. Tavares; Pedro Domingues; João A. P. Coutinho; Mara G. Freire. "Extraction of Immunoglobulin Y using aqueous biphasic systems". Trabalho apresentado em Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  48. Isabel Boal-Palheiros; Tatiana S. M. Vaz; Mafalda R. Almeida; Mara G. Freire. "Novel aqueous biphasic systems composed of phosphonium-based ionic liquids and polyvinylpirrolidone". Trabalho apresentado em Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  49. Mafalda R. Almeida; Helena Passos; Matheus M. Pereira; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Remarkable extraction of antioxidants using ionic liquids as adjuvants in aqueous biphasic systems". Trabalho apresentado em Nanotechnology-from the lab to the industry, Jornadas CICECO 2015, 2015.
  50. Mafalda R. Almeida; Emanuel V. Capela; Helena Passos; João A.P. Coutinho; Mara G. Freire. "Addition of ionic liquids to tune the phases polarities of polymer-salt aqueous biphasic systems". Trabalho apresentado em ECTP2014, 20th European Conference on Thermophysical Properties, 2014.
  51. Mafalda R. Almeida; Ana Filipa M. Cláudio; Mara G. Freire; Erika S. Santos; Joana Pacheco. "Characterization of phenolic compounds from different species of halophytes from Reserva Natural do Sapal de Castro Marim e Vila Real de Santo António". Trabalho apresentado em IMMR’14, Internation Meeting on Marine Research’ 2014, 2014.
  52. Isabel Boal-Palheiros; Tatiana S. M. Vaz; Mafalda R. Almeida; Mara G. Freire. "Novel aqueous biphasic systems composed of phosphonium-based ionic liquids and polivinylpirrolidone". Trabalho apresentado em EUCHEM2014, Conference on Molten Salts and Ionic Liquids, 2014.
  53. Tatiana S. M. Vaz; Mafalda R. Almeida; Isabel Boal-Palheiros; Mara G. Freire. "Aqueous biphasic systems composed of phosphonium-based ionic liquids and polyvinylpyrrolidone". Trabalho apresentado em ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology, 2014.
  54. Mafalda R. Almeida; Emanuel V. Capela; Helena Passos; João A. P. Coutinho; Mara G. Freire. "Tailoring the phases polarities of polymer-salt aqueous biphasic systems by the addition of ionic liquids". Trabalho apresentado em ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology, 2014.
  55. Mafalda R. Almeida; Helena Passos; Álvaro S. Lima; João A. P. Coutinho; Mara G. Freire. "Extraction of antioxidants using aqueous biphasic systems with ionic liquids as adjuvants". Trabalho apresentado em EXIL Workshop 2014, 2014.
  56. Matheus M. Pereira; Rafaela A. P. Cruz; Mafalda R. Almeida; Mara G. Freire. "Ionic liquids as adjuvants in aqueous two-phase systems for the selective extraction of ovalbumin from egg white". Trabalho apresentado em MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013, 2013.
  57. Mafalda R. Almeida; Helena Passos; Mara G. Freire. "Purification of immunoglobulin Y (IgY) using aqueous biphasic systems". Trabalho apresentado em MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013, 2013.
  58. Mafalda R. Almeida; João A. P. Coutinho; Mara G. Freire. "Aqueous biphasic systems composed of polymers and salts: effect of ionic liquids through their phase diagrams". Trabalho apresentado em Summer School on Ionic Liquids, 2013.
  59. Mafalda R. Almeida; Matheus M. Pereira; Helena Passos; João A. P. Coutinho; Mara G. Freire. "Immunoglobulin Y (IgY): a purification platform using ionic-liquid-based aqueous biphasic systems". Trabalho apresentado em Research Day 2013, 2013.
Tese / Dissertação
  1. Mafalda R. Almeida. "Development of purification platforms for immunoglobulin Y using aqueous biphasic systems". Doutoramento, Universidade de Aveiro CICECO, 2018.
  2. Mafalda R. Almeida. "Purification of antibodies using aqueous two-phase systems". Mestrado, Universidade de Aveiro CICECO, 2013.

Propriedade Intelectual

Patente
  1. Mafalda R. Almeida; Judite Resende; Ana P. M. Tavares; Pedro Miguel Dimas Neves Domingues; Mara G. Freire. 2020. "Purification of Immunoglobulin Y and uses thereof".
    Pendente
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/06 Enhanced enzyme reuse through ASNase SILs bioconjugates EUCHEMSIL 2022, 28th EUCHEM Conference on Molten Salts and Ionic Liquids
(Patras, Grécia)
2022/05 Extraction of RuBisCO from spinach leaves using aqueous solutions of biocompatible ionic liquids ISGC 2022, International Symposium on Green Chemistry
(La Rochelle, França)
2021/11/19 ELISA- Enzyme linked immunosorbent assays Microbial Biotechnology class
Universidade de Aveiro (Aveiro, Portugal)
2021/11 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids NEQConSCIENCE Day “Biotech and Chem Edition"
Universidade de Aveiro (Aveiro, Portugal)
2021/11 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids Science & Technology Week
Health Sciences Research Center of the University of Beira Interior (Covilhã, Portugal)
2021/11 Purification of antileukemic drugs through silica-based supported ionic liquids ISPPP 2021, 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides
(Porto, Portugal)
2021/09 Purification of L-asparaginase produced by Bacillus subtilis using silica-based supported ionic liquids 3rd NanoPurAsp Mini Symposium
2021/03 Supported ionic liquid materials for L-asparaginase immobilization 14º Encontro de Química Física
2019/11 Extraction of RuBisCO using aqueous biphasic systems composed of analogues of glycine-betaine ionic liquids BPP 2019, Bipartitiong & Purification Conference
(Guarujá, Brasil)
2019/11 Development of sustainable nanomaterials for the purification of antileukemic drugs 1º Seminário de Cooperação entre as Universidades de Aveiro e São Paulo.
Universidade de São Paulo (São Paulo, Brasil)
2019/11 Continuous separation of PEGylated proteins by fast centrifugal partition chromatography BPP 2019, Bipartitiong & Purification Conference
(Guarujá, Brasil)
2019/11 L-Asparaginase recovery through supported ionic liquid materials based on silica XXV Encontro Galego Portugués de Química, Santiago de Compostela
(Santiago de Compostela, Espanha)
2019/09 Carbon nanomaterials for the purification of antileukemic drugs NANOMAT2019, International Functional Nanomaterials and Nanodevices Conference 2019
(Prague, República Checa)
2019/09 Downstream processing of recombinant proteins using alternative purification platforms ILSEPT 2019, 4th International Conference on Ionic Liquids in Separation and Purification Technology
(Sitges, Espanha)
2019/09 Aqueous biphasic systems applied on the purification of recombinant green fluorescent protein up-scaled by centrifugal partition chromatography ILSEPT 2019, 4th International Conference on Ionic Liquids in Separation and Purification Technology
(Sitges, Espanha)
2019/09 Development of sustainable nanomaterials for the purification of antileukemic drugs ECAB5, 5th European Congress of Applied Biotechnology
(Florence, Itália)
2019/06 Bioprocessing of recombinant proteins using alternative purification platforms Biotec Vigo 2019, Congreso Nacional de Biotecnología 2019
(Vigo, Espanha)
2019/06 Tailoring carbon nanotubes surface chemistry for the purification of antileukemic drugs DCE 2019, 3rd Doctoral Congress in Engineering
Faculdade de Engenharia da Universidade do Porto (Porto, Portugal)
2018/09 Green fluorescent protein purification using centrifugal partition chromatography 12th ESBES, 12th European Symposium on Biochemical Engineering Sciences
(Lisbon, Portugal)
2018/04 Extraction of Green fluorescent protein and its purification using centrifugal partition chromatography 2nd AGChem, 2nd Advances in Green Chemistry Conference
(Poznan, Polónia)
2017/11 Aqueous biphasic systems (ABS) as an alternative platform to purify hen antibodies ESIB 2017, European Summit of Industrial Biotechnology 2017
(Graz, Áustria)
2017/11 Purification of hen immunoglobulins (IgY) using liquid-liquid centrifugal partitioning chromatography (CPC) ABC2, Anything But Conventional Chromatography 2017
(Lisbon, Portugal)
2017/11 Application of bio-based ionic liquids in aqueous biphasic systems to extract value-added compounds from expired energetic drinks ABC2, Anything But Conventional Chromatography 2017
(Lisbon, Portugal)
2017/09 Purification of phenolic compounds in continuous flow by centrifugal partition chromatography BPP2017, Biopartitioning & Purification Conference 2017
(Copenhagen, Dinamarca)
2016/11 Exploring ionic liquids for the development of a purification platform for therapeutic immunoglobulin Y (IgY) from egg yolk XXIIELGQ, XXII Encontro Luso-Galego de Química
(Bragança, Portugal)
2016/05 Addition of ionic liquids to tune the phases polarities of polymer-salt aqueous biphasic systems PATh Spring Workshop
(Ílhavo, Portugal)
2016/05 Purification of IgY using polymer-based aqueous biphasic systems combined with centrifugal partitioning chromatography PATh Spring Workshop
(Ílhavo, Portugal)
2016/05 Aqueous biphasic systems comprising two ionic liquids aiming at the development of improved separation techniques PATh Spring Workshop
(Ílhavo, Portugal)
2015/09 Purification of hen antibodies using aqueous biphasic systems combined with centrifugal partitioning chromatography ECAB 3, 3rd European Congress of Applied Biotechnology
(Nice, França)
2015/05 Novel aqueous biphasic systems composed of two ionic liquids ISGC 2015, 3rd International Symposium on Green Chemistry
(La Rochelle, França)
2014/11 Extaction and identification of added-value compounds from different species of halophytes from Reserva Natural de Sapal de Castro Marim e Vila Real de Santo António Seminar III Sustainable Growing of halophytes
(Castro Marim, Portugal)
2014/07 Ionic liquids as additives to improve the extraction of antioxidants in aqueous biphasic systems ILSEPT, 2nd International Conference on Ionic Liquids in Separation and Purification Technology
(Toronto, Canadá)
2013/12 Purification of Immunoglobulin Y (IgY) using aqueous biphasic systems MicroBiotec13, Portuguese Congress of Microbiology and Biotechnology' 2013
(Aveiro, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022/03 - 2022/12/16 Antileukemic biopharmaceuticals production and purification using nanomaterials
Coorientador
 Engenharia Química (Mestrado)
Universidade de Aveiro, Portugal
2021/09 - 2022/12 Produção e purificação de L-asparginase utilizando líquidos iónicos suportados
Orientador
 Biotecnologia (Mestrado)
Universidade de Aveiro, Portugal
2022/02 - 2022/07 Purificação da L-asparaginase utilizando líquidos iónicos suportados
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Líquidos iónicos suportados em sílica para a extração e purificação da L-asparaginase
Coorientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Extração e purificação da L-asparaginase utilizando líquidos iónicos suportados em sílica
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2021/02 - 2021/07 Otimização da produção de L-asparaginase por Bacillus subtillis
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/09 - 2020/12/17 RuBisCO extraction and purification: from residual biomass to value added protein
Coorientador
 Biotecnologia (Mestrado)
Universidade de Aveiro, Portugal
2019/09/18 - 2020/12 Optimization of L-asparaginase production by Bacillus Subtilis
Coorientador
 Biotecnologia (Mestrado)
Universidade de Aveiro, Portugal
2020/02 - 2020/07 Otimização da produção de L-asparaginase por Bacillus Subtillis
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/02 - 2020/07 Extração de biomoléculas utilizando sistemas aquosos bifásicos
Coorientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Purification of human serum IgG with functionalized carbon nanomaterials
Coorientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Supported ionic liquids for the extraction and purification of L-asparaginase
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/02 - 2019/07 Carbon nanomaterials for the extraction and purification of L-asparaginase
Orientador
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2021/09 - 2021/10 Co-organizer of 3rd NanoPurAsp Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs (2021/10)
Simpósio
 Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brasil
2020/10/01 - 2020/10/10 Co-organizer of Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs within the 2nd year of the NanoPurAsp project (2020/11/09 - 2020/11/10)
Simpósio (Coorganizador)
 Universidade de Aveiro, Portugal
2014/08 - 2014/09 Co-organizer of 20th European Conference on Thermophysical Properties (ECTP 2014) (2014/08/31 - 2014/09/04)
Conferência (Outra)
 Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Aveiro CICECO, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2023/04/26 - 2023/04/27 Participation in Tetrapyrrole Discussion Group Meeting. Poster presentation.
Encontro
 Tetrapyrrole Discussion Group Meeting
University of Kent, Reino Unido
2023/02/10 - 2023/02/11 Participation in 2nd Symposium on Alzheimers Disease: An Update on Pathology and Therapeutics
Simpósio
 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics
Universidade do Porto Faculdade de Engenharia, Portugal
2023/02/08 - 2023/02/08 Participation in LS4FUTURE - 1st General Meeting
Encontro
 LS4FUTURE - 1st General Meeting
2022/11/18 - 2022/11/18 Participation in CoLife Postdoc Day
Outro
 CoLife Postdoc Day
Instituto Gulbenkian de Ciência, Portugal
2022/10/14 - 2022/10/14 Participation in V International Conference NOVAhealth Chronic Disease and Infection
Conferência
 V International Conference NOVAhealth Chronic Disease and Infection
Universidade Nova de Lisboa, Portugal
2022/07 - 2022/07 Participation in the Final Annual Meeting of Twin to illuminate metal in biology and biocatalysis through biospectroscopy. Poster presentation.
Encontro
 Final Annual Meeting of Twin to illuminate metal in biology and biocatalysis through biospectroscopy
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/11 - 2021/11 Participation in NEQConSCIENCE Day Biotech and Chem Edition, with an invited oral presentation
Oficina (workshop)
 NEQConSCIENCE Day
Universidade de Aveiro, Portugal
2021/11 - 2021/11 Participation in Science & Technology Week, from Health Sciences Research Center of the University of Beira Interior, with an invited oral presentation
Oficina (workshop)
 Science & Technology Week
Universidade da Beira Interior, Portugal
2021/11 - 2021/11 Participation in the 40th International Symposium on the Purification of Proteins, Peptides and Polynucleotides (ISPPP 2021). Both poster and oral presentations.
Congresso
Universidade da Beira Interior, Portugal
2021/10/14 - 2021/10/16 Participation in TechDays 2021, Aveiro, Portugal. In this event I show the work that I developed under the NanoPurAsp Project
Exposição
 TechDays 2021
Universidade de Aveiro, Portugal
2021/09 - 2021/09 Participation in 3rd NanoPurAsp Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs, with an invited oral presentation
Simpósio
 3rd NanoPurAsp Mini Symposium
Universidade Estadual Paulista Júlio de Mesquita Filho Câmpus de Araraquara Faculdade de Ciências Farmacêuticas, Brasil
2020/11/09 - 2020/11/10 Participation in Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs
Simpósio
 Mini Symposium - Development of sustainable nanomaterials for the purification of antileukemic drugs
Universidade de Aveiro, Portugal
2020/09/21 - 2020/09/21 Participation in PATh/IonCytDevice Workshop: A Technological Perspective on Cancer: from Diagnosis and Treatment to Environmental Fate and Remediation
Oficina (workshop)
 PATh/IonCytDevice Workshop-A Technological Perspective on Cancer: from Diagnosis and Treatment to Environmental Fate and Remediation
Universidade de Aveiro, Portugal
2019/11/11 - 2019/11/13 Participation in BPP 2019 Biopartitioning & Purification Conference. Both poster and oral presentations. BPP 2019 Biopartitioning & Purification Conference
2019/11/08 - 2019/11/08 Participation in 1º Seminário de Cooperação entre Universidades de Aveiro e São Paulo, with an invited oral presentation.
Encontro
 1º Seminário de Cooperação entre Universidades de Aveiro e São Paulo
Universidade de São Paulo, Brasil
2019/10/10 - 2019/10/12 Participation in TechDays 2019, Aveiro, Portugal. In this event I show the work that I developed under the NanoPurAsp Project
Exposição
 TechDays 2019
2019/09/15 - 2019/09/19 Participation in 5th European Congress of Applied Biotechnology - ECAB5. Poster presentation.
Conferência
 5th European Congress of Applied Biotechnology - ECAB5
Associazione Italiana Di Ingegneria Chimica, Itália
2019/06/11 - 2019/06/12 Participation in Jornadas CICECO 2019: Where Science meets Society
Conferência
 ornadas CICECO 2019: Where Science meets Society
Universidade de Aveiro CICECO, Portugal
2019/05/17 - 2019/05/17 Participation in the 4th Meeting on Medicinal Biotechnology. This event is focus on Red Biotechnology (Health Biotechnology), and intends to present and disseminate relevant work done in this field.
Encontro
 4th Meeting on Medicinal Biotechnology
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/04/11 - 2019/04/11 Participation in PAth Spring Workshop: Deeping in the Eutectic Mixtures & Polymers
Oficina (workshop)
 PAth Spring Workshop
Universidade de Aveiro CICECO, Portugal
2018/06/11 - 2018/06/12 Participation in Jornadas CICECO 2018
Encontro
 Jornadas CICECO 2018 - living science together
Universidade de Aveiro CICECO, Portugal
2018/03/22 - 2018/03/24 Participation in UA Open Campus 2018. In this event I show the work that I was developing in my PhD regarding the purification of antibodies from egg yolk.
Exposição
 UA Open Campus 2018
Universidade de Aveiro, Portugal
2017/11/22 - 2017/11/24 Participation in Anything But Conventional Chromatography 2017 (ABC2). Oral presentations.
Congresso
 ABC2 - Anything But Conventional Chromatography
European Society of Biochemical Engineering Sciences, Alemanha
2017/11/14 - 2017/11/16 Participation in European Summit of Industrial Biotechnology 2017 (ESIB2017). Both oral and poster presentations.
Congresso
 ESIB 2017 - European Summit of Industrial Biotechnology 2017
Austrian Centre of Industrial Biotechnology, Áustria
2017/10/12 - 2017/10/14 Participation in TechDays 2017, Aveiro, Portugal. In this event I show the work that I was developing in my PhD regarding the purification of antibodies from egg yolk.
Exposição
 TechDays2017
Universidade de Aveiro, Portugal
2017/06/08 - 2017/06/08 Participartion in the 2nd edition of PATh Spring Workshop.
Oficina (workshop)
 PATh Spring Workshop
Universidade de Aveiro CICECO, Portugal
2016/06/08 - 2016/06/09 Participation in Jornadas CICECO 2016. Poster presentation.
Encontro
 nergy: trends and future chalenges - Jornadas CICECO 2016
Universidade de Aveiro CICECO, Portugal
2016/05/09 - 2016/05/09 Participation in Path Spring Workshop. Two oral presentations.
Oficina (workshop)
 PATh Spring Workshop
Universidade de Aveiro CICECO, Portugal
2016/02/10 - 2016/02/11 Participation in a chromatography seminar.
Seminário
 Chromatography seminar
TECNOCROMA, Portugal
2015/09/27 - 2015/10/01 Participation in the 3rd European Congress of Applied Biotechnology (ECAB 3). Both poster and oral presentations.
Congresso
 ECAB 3 - 3rd European Congress of Applied Biotechnology
European Federation of Chemical Engineering, França

European Society of Biochemical Engineering Sciences, Alemanha
2015/06/07 - 2015/06/10 Participation in Biopartitioning & Purification Conference 2015 (BPP 2015). Poster presentation.
Congresso
 BPP 2015 - Biopartitioning & Purification Conference 2015
Austrian Centre of Industrial Biotechnology, Áustria
2015/04/14 - 2015/04/15 Participation in Jornadas CICECO 2015. Poster presentation.
Encontro
 Nanotechnology-from the lab to the industry, Jornadas CICECO 2015
Universidade de Aveiro CICECO, Portugal
2014/08/31 - 2014/09/04 Participartion in the 20th European Conference on Thermophysical Properties (ECTP 2014). Poster presentation.
Conferência
 ECTP 2014 - 20th European Conference on Thermophysical Properties
Universidade do Porto Faculdade de Ciências, Portugal

Universidade de Aveiro CICECO, Portugal
2014/06/29 - 2014/07/02 Participation in the 2nd International Conference on Ionic Liquids in Separation and Purification Technology (ILSEPT). Both poster and oral presentations.
Congresso
 ILSEPT 2014, 2nd International Conference on Ionic Liquids in Separation and Purification Technology
Elsevier BV, Países Baixos
2014/04/24 - 2014/04/26 Participation in Liquid/liquid extraction by use of Ionic Liquids workshop. Poster presentation.
Oficina (workshop)
 Liquid/liquid extraction by use of Ionic Liquids workshop
EXIL - EXchange on Ionic Liquids, Bélgica
2013/12/06 - 2013/12/08 Participation in Portuguese Congress of Microbiology and Biotechnology 2013 (MicroBiotec'13). Both poster and oral presentation.
Congresso
 MicroBiotec'13, Portuguese Congress of Microbiology and Biotechnology 2013,
Portuguese Society of Microbiology, Portugal
2013/06/09 - 2013/06/12 Participation in "Summer School on Ionic Liquids". Poster presentation.
Conferência
 Summer School on Ionic Liquids
La Red Gallega de Líquidos Iónicos, Espanha
2013/06 - 2013/06 Participation in Research Day 2013. Poster presentation.
Encontro
 Research Day 2013

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/11/26 Specific Avian Antibodies, Immunoglobulin Y (IgY), as Biopharmaceuticals to Tackle Multirresistent Bacteria
Arguente principal
 Débora Sofia Tavares de Sousa (Mestrado)
Universidade de Aveiro, Portugal
2022/12/16 Purification of immunoglobulin G-based biopharmaceuticals using supported ionic liquids
Arguente principal
 Mariana Meireles e Castro (Mestrado)
Universidade de Aveiro, Portugal
2022/12/16 Produção e purificação de biofármacos anti-leucémicos
Orientador
 Tatiana Domingues Ferreira (Mestrado)
Universidade de Aveiro, Portugal
2022/12/14 Valorisation of plastic waste: degradation based on enzymatic depolymerization
Arguente principal
 Mariana Isabel dos Santos Aguiar (Mestrado)
Universidade de Aveiro, Portugal
2022/07/29 Purification and stability of antibodies using alternative materials and solvents
Arguente principal
 Ana Sofia Correia Marques (Mestrado)
Universidade de Aveiro, Portugal
2022 Innovative and sustainable platforms for the downstream processing of antibody-based biopharmaceuticals
Arguente
 Emanuel Augusto Vieira Capela (Doutoramento)
Universidade de Aveiro, Portugal
2021/07/28 Integrated recovery-purification strategies of protein-based biopharmaceuticals
Arguente principal
 João Luís Pereira Fernandes (Outro)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2020/12/18 Optimization of L-asparaginase production by Bacillus Subtilis
Orientador
 Daniel Figueiredo de Castro (Mestrado)
Universidade de Aveiro, Portugal
2020/07/24 Carbon nanotubes as a novel platform for L-asparaginase immobilization
Arguente principal
 João Gonçalves Pinho (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2022/10 - Atual Pharmaceuticals MDPI
2022/09 - Atual Scientific Reports Nature
2022/09 - Atual Fermentation MDPI
2022/01 - Atual Molecules MDPI
2021/10 - Atual Foods (2304-8158) MDPI
2020/12 - Atual Journal of Chemistry Hindawi
2020/05 - Atual Separation and Purification Technology (1383-5866) Elsevier
2022 - 2022 BioTech-Guest Editor of the Special Issue: Progress on the Production, Purification and Applications of Microbial Enzymes MDPI

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2021/07/13 - Atual Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Chemical Enginnering curricular plan from Flávia Carina Freitas Magalhães Universidade de Aveiro, Portugal
2021/02 - Atual Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Biotecnhology curricular plan from Ana Catarina Almeida Santos Universidade de Aveiro, Portugal
2021/02 - Atual Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Biotecnhology curricular plan from João Cláudio Fonseca Nunes Universidade de Aveiro, Portugal
2019/07 - Atual Jury member in the evaluation of Thesis Proposal Preparation-Doctorate in Chemical Engineering curricular plan from Marguerita Evangelho da Rosa Universidade de Aveiro, Portugal
2016/04 - Atual In the aim of the 8th Biochemistry Day at University of Aveiro, the BSc and MSc students in Biochemistry were invited to present their works in the form of a poster, based on the available bibliography, current knowledge or student’s experience on the subject. Me and my colleagues, PhD students in Biochemistry, evaluated the posters and decided the top three winners. Universidade de Aveiro Departamento de Química, Portugal
2017/04 - 2017/04 In the aim of the 9th Biochemistry Day at University of Aveiro, the BSc and MSc students in Biochemistry were invited to present their works in the form of a poster, based on the available bibliography, current knowledge or student’s experience on the subject. Me and my colleagues, PhD students in Biochemistry, evaluated the posters and decided the top three winners. Universidade de Aveiro Departamento de Química, Portugal

Tutoria

Tópico Nome do aluno
2016/09 - 2017/10 MSc thesis Filipe Miguel Garcia Ferreira
2015/09 - 2016/07 MSc thesis Juliana Meixedo Calheiros
2014/09 - 2015/07 MSc thesis Joana Margarida Mota Gomes
2014/09 - 2015/05 MSc thesis Judite Sofia Santos Resende
2014/02 - 2014/07 BSc final project Emanuel Augusto Vieira Capela
Distinções

Prémio

2021 Best Poster Award
International Symposium on the Separation of Proteins, Peptides & Polynucleotides, Portugal
2017 Best Poster Award
Biopartitioning & Purification Conference, Brasil
2017 2nd Place at Conference Contest for Young Researchers
European Society of Biochemical Engineering Sciences, Alemanha
2016 Best Poster Award
Encontro Nacional de Estudantes de Química, Portugal

Outra distinção

2022 Article highlighted on the Sustainable Chemistry homepage
MDPI AG, Suiça
2019 Honorable Mention
Biopartitiong & Purification Conference 2019, Brasil