Curriculum Vitae
Filipa Sofia Silva Engrola
Identification
Personal identification
- Full name
- Filipa Sofia Silva Engrola
Citation names
- Engrola, Filipa
- Filipa S. S. Engrola
Author identifiers
- Ciência ID
- 4219-13FE-6152
- ORCID iD
- 0000-0002-7066-5126
Email addresses
- f.engrola@campus.fct.unl.pt (Professional)
Telephones
- Telephone
-
- 212948300 Ext.: 10962 (Professional)
Websites
Education
| Degree | Classification | |
|---|---|---|
|
2021/05/01 - 2025/05/01
Ongoing
|
Doctoral Program in Biochemistry (Doutoramento)
Major in Structural Biochemistry
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal |
|
|
2017/09 - 2019/11
Concluded
|
Bioquímica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Bacterial arsenite oxidation at the molecular level " (THESIS/DISSERTATION)
|
|
|
2014/09 - 2017/07
Concluded
|
Bioquímica (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Phase transformations and controlled delivery of an ionic liquid derived from
Ibuprofen" (THESIS/DISSERTATION)
|
Affiliation
Science
| Category Host institution |
Employer | |
|---|---|---|
| 2021/05/01 - Current | Research Trainee (Research) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal (...) |
||
| 2020/05/01 - 2021/04/30 | Research Trainee (Research) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal | ||
| 2018/09 - 2019/11 | Research Trainee (Research) | Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal | ||
| 2017/07/01 - 2017/07/31 | Research Trainee (Research) | Universidade de Lisboa Instituto Superior Técnico, Portugal |
| Universidade de Lisboa Instituto Superior Técnico, Portugal |
Projects
Grant
| Designation | Funders | |
|---|---|---|
| 2020/05/01 - 2021/04/30 | BACTERIAL ABC-TYPE MULTITASK ENERGIZERS: ONE ATPASE FITS ALL?
Research Fellow
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
Outputs
Publications
| Book chapter |
|
| Conference poster |
|
| Thesis / Dissertation |
|
| Working paper |
|
Artistic / Performance
| Video recording |
|
Activities
Oral presentation
| Presentation title | Event name Host (Event location) |
|
|---|---|---|
| 2023/06/07 | Enzyme-substrate & protein-protein interaction: the case study of Arsenite oxidase (Flash presentation) | Affinity 2023 - 25th meeting of the International Society for Molecular Recognition, Portugal
(Lisboa, Portugal)
|
| 2023/05/26 | Arsenite oxidase interaction with substrates and partners: a structural and biophysical characterization (Flash Presentation) | 8th International School of Biological Crystallization - ISBC 2023, Spain
(Granada, Spain)
|
| 2022/07/16 | Arsenite oxidase: a complex enzyme to tackle a complex environmental problem: arsenite water contamination | 2nd National Crystallographic Meeting
Técnico Lisboa - Universidade de Lisboa (Lisboa, Portugal)
|
| 2021/09/21 | Flash talk - How to choose a good electron partner for arsenite oxidase? | 12th Molybdenum and Tungsten Enzymes Conference, MoTEC21
Virtual (Marseille, France)
|
| 2019/07 | Arsenite oxidase: from the substrate analogue to the electron acceptors – Structural and functional insights | The 8th Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019)
Faculty of Sciences of University of Porto (FCUP) (Porto, Portugal)
|
| 2019/03 | Bacterial arsenite oxidation at the molecular level – Protein crystallography and Small Angle X-ray Scattering | VII Encontro Nacional de Estudantes de Química 2019 / "VII National Meeting of Chemistry Students" (ENEQUI '19)
NOVA School of Science and Technology (FCT NOVA) (Caparica, Portugal)
|
| 2019/02/15 | Bacterial arsenite oxidation at the molecular level – Protein crystallography and Small Angle X-ray Scattering | Jornadas Intercalares das Dissertações Anuais dos Mestrados do Departamento de Química e do Departamento de Ciências da Vida
(JIM)
Universidade Nova de Lisboa (Portugal)
|
| 2018/11/28 | Amor à Primeira Vista - as hormonas / Love at first sight - the hormones | World's Biggest Chemistry Class Cascais 2018/ A Maior Aula de Química do Mundo Cascais 2018
CASCAIS 2018 - CAPITAL EUROPEIA DA JUVENTUDE (Cascais, Portugal)
|
Supervision
| Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
|---|---|---|
| 2023/11/01 - 2024/01/01 | Structural studies in an arsenite oxidase - Rotações laboratoriais em Técnicas Biomoleculares I
Co-supervisor of Guilherme Oliveira
|
Biochemistry (Specialization course)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2022/07 - 2022/07 | ESCOLA DE VERÃO UCIBIO 2022 Iniciação à Investigação em Ciências Biomoleculares Aplicadas - Estudos estruturais e funcionais
com duas enzimas de molibdénio
Co-supervisor
|
Biochemistry (Scientific initiation)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2022/02 - 2022/06 | Projecto final de Bioquímica - Compreender o mecanismo enzimático para a detoxificação de arsénio com vista à produção de
novos biossensores
Co-supervisor
|
Bioquímica (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
Event organisation
| Event name Type of event (Role) |
Institution / Organization | |
|---|---|---|
| 2019/04 - Current | Volunteer in hosting and organizing an event at EXPO-FCT 2019. This annual event is destined to present the faculty and its
educational offer, which aims to facilitate the choice of higher education by young pre-university students, through demonstrations
and activities in science and engineer areas. (2019/04/23)
Exhibition (Co-organisor)
|
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| 2017/09/01 - Current | Founding member of the “Núcleo de estudantes de Bioquímica FCT-UNL (NuBioq)” (2017/09/01)
Exhibition (Member of the Organising Committee)
|
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| 2016/11/25 - Current | This lecture aimed to clarify how it is to work within the scientific community, tips on how to build a solid career and how
to deal with the struggles. Pedro Viana Baptista, Professor at FCT-NOVA and Helena Santos, Professor at ITQB were the invited
guests. (2016/11/25)
Seminar (President of the Organising Committee)
|
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal |
| 2019/03 - 2019/03 | Laboratory experiments planning for
primary school students. (2019/03 - 2019/03)
Exhibition (Member of the Organising Committee)
|
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal Agrupamento de Escolas Professor Armando de Lucena, Portugal |
| 2016/06 - 2017/06 | Former Director "área educativa do núcleo de estudantes de Bioquímica FCT-NOVA". Charity, science communication or mentoring
are some of the activities developed to help the student body. (2016/06)
Exhibition (President of the Organising Committee)
|
Event participation
| Activity description Type of event |
Event name Institution / Organization |
|
|---|---|---|
| 2022/07/08 - Current | The FEBS Congress is one of the most visible activities of FEBS. As one of the largest bio-congresses in Europe, featuring
up to approx. 2500 attendees, the Congress provides a platform for international scientific exchange and showcases the newest
developments in biochemistry, molecular biology and related areas. The Congress comprises plenary lectures presented by outstanding
scientists including Nobel Laureates, and a range of subject-specific symposia to provide the latest updates in different
areas of bioscience research.
Conference
|
IUBMB-FEBS-PABMB 2022 CONGRESS
Federation of European Biochemical Societies, United Kingdom
|
| 2019/07/28 - Current | Researchers, users of synchrotron radiaton from any infrastructure and research field present their recent works both by oral
and poster communications.
Conference
|
The 8TH Meeting of Portuguese Synchrotron Radiation Users (ENURS 2019)
Universidade do Porto Faculdade de Ciências, Portugal
|
| 2018/11/28 - Current | Key speaker at the World Guinness Record "World's Biggest Chemistry Class Cascais 2018/A Maior Aula de Química do Mundo Cascais
2018". A science communication event that took place in Cascais, where 1440 elementary school students learned about chemistry.
Seminar
|
World's Biggest Chemistry Class Cascais 2018/ A Maior Aula de Química do Mundo Cascais 2018 |
| 2024/01/03 - 2024/01/05 | CCP4 Study Weekend 2024 - “Decision making in MX – how to be a productive structural biologist”
Conference
|
CCP4 Study Weekend 2024 - “Decision making in MX – how to be a productive structural biologist”
University of Nottingham School of Biosciences, United Kingdom
|
| 2023/06/21 - 2023/06/21 | The meeting provides an opportunity to hear about the developments upgrades and new opportunities at the European Synchrotron
Research Facility in Grenoble France and the Alba Synchrotron Light Source in Barcelona, Spain. The meeting also provides
opportunities for users to share their recent research via oral or poster presentations.
Meeting
|
9th National Meeting of Synchrotron Radiation Users - ENURS 2023, Portugal
Instituto Politécnico de Leiria, Portugal
|
| 2023/06/05 - 2023/06/07 | Global scientific event that covers fundamental and applied aspects of molecular recognition and affinity technology in industry
for health and disease, bioprocessing and biosensing.
Conference
|
Affinity 2023 - 25th meeting of the International Society for Molecular Recognition, Portugal |
| 2023/05/21 - 2023/05/28 | The Laboratory of Crystallographic Studies (LEC) hosted the ISBC2023 in Granada (Spain) for the eighth time. The school provided
five days of lectures and practical demonstrations on the crystallization of biological macromolecules, including large crystals
for neutron diffraction and tiny crystals for XFEL or EM. One day was devoted to case studies on the crystallization of membrane
proteins, viruses, large macromolecular complexes, and sample preparation for cryoEM.
Workshop
|
8th International School of Biological Crystallization - ISBC2023, Spain |
| 2022/09/25 - 2022/09/30 | The main objective of the course is to provide the fundamental concepts and integrative hands-on applications of Macromolecular
Crystallography (MX), Nuclear Magnetic Resonance (NMR), Magnetic Resonance Mass Spectrometry (MRMS) and single-particle analysis
Cryo-Electron Microscopy (EM) in structural biology. The major strengths and limitations associated with each technique will
be also highlighted and discussed along with their complementarity to achieve truly integrative structural biology approaches
to tackle challenging science.
Workshop
|
Joint Instruct-iNEXT Course: Integrating Structural Biology Techniques
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
| 2020/08/09 - 2020/10/09 | This annual meeting gathers synchrotron users, at a scientific event that includes presentations in plenary, poster, and parallel
sessions. Participants are able to learn about current/future facility capabilities and the latest user research as well as
to discuss science with colleagues from academia, research laboratories, and industry worldwide.
Conference
|
2020 Virtual SSRL/LCLS Users' Meeting
Stanford Synchrotron Radiation Lightsource, United States
|
| 2020/05/05 - 2020/06/02 | This online course aims at young biochemists/biophysicists and researchers active in related structural methods with little
or no experience in solution scattering. The course covered basics of SAXS, instrumentation, sample preparation, modelling
techniques and complementary use with other methods.
Workshop
|
Solution Scattering from Biological Macromolecules
European Molecular Biology Laboratory Hamburg, Germany
|
| 2020/02/20 - 2020/02/20 | Practical and theoretical insights into ChemDraw and Reaxys software.
Workshop
|
Chemistry Software Workshop: ChemDraw and Reaxys
Universidade Nova de Lisboa, Portugal
|
| 2019/11 - 2019/11 | Protein purification workshop
Workshop
|
Protein purification workshop: Technical tips & tricks Column replacement day
GE Healthcare Healthcare Systems, Netherlands
|
| 2019/06 - 2019/06 | “Rock the elements – The challenge” was an event where scientists, students and the general public were invited to produce a science communication video, aiming to disseminate scientific knowledge. | 3rd place in “Rock The elements – the challange”
Universidade Nova de Lisboa, Portugal
|
| 2019/05/22 - 2019/05/24 | International Structural Biology conference | Instruct Biennial Structural Biology Conference: Deeper into the Cell
Instruct-ERIC, Spain
|
| 2019/05/22 - 2019/05/22 | Women in Science Workshop - Instruct-ERIC.
Practical advice from leading women scientists in industry and academia and discussions about how Instruct-ERIC can support
our community to progress in their careers.
Workshop
|
Women in Science Workshop - Instruct-ERIC
INSTRUCT-ULTRA, Spain
|
| 2019/03/22 - 2019/03/25 | At the National Meeting of Chemistry Students (in Portuguese, Encontro Nacional de Estudantes de Química) all chemistry students
can attend presentations of national and international speakers, as well as participate in workshops.
Conference
|
VII National Chemistry Students Meeting (ENEQUI '19)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2019/03 - 2019/03 | Leacture and laboratory activity to middle school students about the importance of the elements of the periodic table in our
lives.
Exhibition
|
Escola Básica e Secundária Professor Armando de Lucena, Portugal
|
| 2018/09/28 - 2018/09/28 | The UCIBIO Annual Meeting counts with 3 keynote speakers, invited speakers from industry, Presentations and Flash Presentations
on the Thematic Lines, and Poster Sessions.
Meeting
|
UCIBIO anual meeting 2018
Universidade Nova de Lisboa, Portugal
|
| 2018/03 - 2018/03 | International science communication contest, sponsored by the British Council and integrated in the National Geographic Summit.
Exhibition
|
Fame LAb
British Council Portugal, Portugal
|
| 2017/07/24 - 2017/07/25 | Supramolecular Chemistry Workshop.
1) Basic principles of supramolecular chemistry and molecular recognition.
2) Practical Class: Determination of an association constant of an inclusion complex.
3) Molecular recognition of neutral and ionic molecules - case studies.
Workshop
|
Supramolecular Chemistry Workshop
Universidade Nova de Lisboa, Portugal
|
| 2017/07 - 2017/07 | Summer internship where students integrate a research team at IST and work in a project and learn about the workings of the
institute, how to develop their ideas and do a presentation at the end.
Workshop
|
Técnico Summer Internships 2017
Universidade de Lisboa Instituto Superior Técnico, Portugal
|
Mentoring / Tutoring
| Topic | Student name | |
|---|---|---|
| 2019/10 - 2019/10 | Support in the supervision of a MSc Student in the Biomolecular Techniques subject | Marlene Cunha |
| 2019/10 - 2019/10 | Support in the supervision of a MSc Student in the Biomolecular Techniques course | Kleyde Delgado |
| 2019/04 - 2019/04 | Suport in the supervion of a BSc Student during a laboratory internship | Rita Jesus |
Scientific expedition
| Activity description | Institution / Organization | |
|---|---|---|
| 2022/09/05 - 2022/09/16 | Human Norepinephrine Transporter expression trials were conducted in an insect cell system, under the supervision of Dr. Manuel Etzkorn, at the Institute of Physical Biology Heinrich-Heine-Universität and Dr. Aldino Viegas, at UCIBIO@NOVA. These tests were conducted under the scope of the project "Biochemical, functional and structural studies of the human norepinephrine transporter", 2021.09576.CBM. | Heinrich-Heine-Universität Düsseldorf, Germany |
| 2021/10/01 - 2021/12/01 | Unravelling arsenite oxidation reaction mechanism through Time-resolved Crystallography. Experience in sample preparation and optimisation for serial crystallography; knowledge on serial data collection using fixed targets at the T-REXX endstation @ PETRA III, Hamburg; data processing and structure determination. | Universität Hamburg Hamburg Centre for Ultrafast Imaging, Germany |
Distinctions
Award
| 2023 | Best Poster Award - ENURS 2023
9th National Meeting of Synchrotron Radiation Users - ENURS 2023, Portugal
|
| 2023 | Best Poster Award - ISBC 2023
8th International School of Biological Crystallization, ISBC2023, Spain
|
| 2023 | Younger Investigator Award for Best Flash Presentation - Affinity 2023
• Affinity 2023 - 25th meeting of the International Society for Molecular Recognition, Portugal, Portugal
|
| 2020 | EMBL Workshop fellowship
European Molecular Biology Laboratory, France
|
| 2020 | Best Poster Award - In situ Structural Biology: From Cryo-EM to Integrative Modelling
European Molecular Biology Laboratory, Germany
|
| 2019 | Instruct-ERIC Women in Science fellowship award
INSTRUCT-ULTRA, Spain
|
| 2019 | Best presentation at "Jornadas Intercalares dos mestrados do Departamento de Química e Ciências da Vida 2018/2019"
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
| 2019 | 3rd place in - Rock The elements - the challange |
Title
| 2018 | Semi-finalist at FameLAB contest
FameLab, Portugal
|
Other distinction
| 2024 | Travel Bursery
CCP4 Study Weekend 2024 , United Kingdom
|