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E. Logarinho concluded her PhD in Biomedical Sciences by the University of Porto (UP) in 2002. After her PhD, embraced a full-time professorship career path. E. Logarinho became an Assistant Professor at the ISCS-N/CESPU Health Sciences School (2002-2007), and in 2007, she joined the Medical School/ICVS/UMinho as full-time Assistant Professor (2007-2009). In 2009, E. Logarinho returned to full-time research career path under Ciência 2008 program, joining H. Maiato lab at IBMC. Her work on mechanisms ensuring mitotic spindle-pole integrity (Nat Cell Biol 2012, 1st author) was acknowledged with an invited review in Nat Cell Biol 2014 (co-senior author) and Pfizer 2011 and SPGH 2013 prestigious national prizes. In July 2013, she was awarded a Junior Researcher position funded by ON.2/QREN/FEDER to launch innovative research lines at IBMC (now part of the i3S Consortium/UP). In 2015, she was highly recommended by the IBMC External Advisory Board for an independent research group status, and simultaneously awarded with an FCT Investigator competitive grant. Currently, she holds a CEEC (FCT scientific employment) position and leads the Aging & Aneuploidy group, composed of 5 Post-Docs (2 CEEC), 2 PhD and 2 MSc students , dedicated to high-profile research on molecular mechanisms contributing to aging and age-related diseases. Her group applies interdisciplinary approaches to address how regulated instruction of proliferative fitness and genomic stability decelerates senescence in mouse models of Down syndrome, progeria and aging. Within i3S Cancer Program, E. Logarinho is tackling the question on how aging is the major risk factor for tumorigenesis, with focus on CIN and senescence. The originality of her work has caught international recognition as attested by the Maximon Longevity Prize 2022, a strong collaborative network and track record, the delivery of invited talks in prestigious conferences (e.g. Salk Institute, CNIO, CSHL, ERIBA), the evaluation of international grants as expert, invited reviews, and co-chairing of a Forbeck forum in Cancer. Selected publications, out of 18 in the last 5 years, include as senior/co-senior author: Nat Aging, Nat Commun, Embo Rep, Cell Death Dis. The past quinquennial was auspicious to her career consolidation: i) in managing a team (completed the supervision of 7 PhD, 4 MSc and 2 Post-Docs); ii) in securing funding (as a PI, secured >1.7M euros competitive funding in grants: 4 FCT national grants; 1 grant from Progeria Research Foundation; 1 grant from Jeróme Lejeune Foundation; 1 grant from Compete 2020/Portugal2020 in co-promotion with Insparya company, plus 3 CEEC postdoctoral positions (1 PI, 1 Assistant and 1 Junior) (>1.1M euros), and 7 PhD fellowships (>500k euros); moreover, the IR was a work package leader in 3 institutional network grants funded by Norte2020/Portugal2020, participant in a H2020-WIDESPREAD-2020-5 Twinning project (PhasAGE), and co-PI in a FCT project awarded to CEEC team member); and iii) in collaborating in-house within all i3S Integrative Programs. Besides her core scientific activities, the IR was vice-coordinator of the Cancer Program and member of the Restrictive Scientific Council at i3S during 2019-2022, and she has been continuously involved in MSc/PhD lectures and examinations and in outreach activities. She is also a Research Consultant at the Insparya Hair Company. E. Logarinho co-authored a total of 43 publications with >2300 citations and an h-index of 25 (Google Scholar). E. Logarinho had 3 maternity leaves (2004, 2011, 2012) and an unconventional path due to professorship career (2001-2009).
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Identification

Personal identification

Full name
Elsa Logarinho

Citation names

  • Logarinho, Elsa

Author identifiers

Ciência ID
441F-F340-784C
ORCID iD
0000-0002-8741-0744
Scopus Author Id
6506315519

Email addresses

  • elsa.logarinho@ibmc.up.pt (Professional)

Telephones

Telephone
  • 220408800 Ext.: 6129 (Professional)

Addresses

  • Instituto de Investigação e Inovação em Saúde, i3S; Instituto de Biologia Molecular e Celular, IBMC; Ageing and Aneuploidy Group. Rua Alfredo Allen, 208, 4200-135 , Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Elementary (A2)
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2002/01/10
Concluded
 Doutoramento em Ciências Biomédicas, domínio de especialização em Genética Molecular da Mitose (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Regulation of cell cycle progression in Drosophila melanogaster" (THESIS/DISSERTATION)
 Aprovada por unanimidade
1994/09/19
Concluded
 Licenciatura em Bioquímica, ramo de especialização em Bioquímica Fundamental (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Relatório de estágio: Análise fenotípica e molecular de mutantes do ciclo celular em Drosophila melanogaster" (THESIS/DISSERTATION)
 15 valores
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2013/09/15 - 2014/09/15 Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
2007/02/01 - 2009/01/31 Assistant Professor (University Teacher) Universidade do Minho Escola de Medicina, Portugal
2002/02/01 - 2007/01/31 Assistant Professor (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2001/01/01 - 2002/01/31 Assistant (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
1999/10/01 - 2000/12/31 Invited Assistant (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
1994/10/01 - 1999/07/31 Invited Assistant (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Others

Category
Host institution 		Employer
2017/01/13 - Current Group Leader - Aging and Aneuploidy Lab Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/07/01 - Current Group Leader - Aging and Aneuploidy Lab Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2021/04/01 - 2027/03/31 Emprego Científico Individual 2020 - Principal Investigator 2020.00654.CEECIND Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/07/01 - 2020/06/30 FCT Investigator (Starting Grant for Auxiliary level) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/07/01 - 2015/06/30 Auxiliary Researcher - ON.2/QREN/FEDER Starting grant Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2009/07/01 - 2013/06/30 Auxiliary Researcher - Programa Ciência 2008 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2007/02/01 - 2009/01/31 Affiliate Post-Doc Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2002/01/11 - 2007/01/31 Affiliate Post-Doc Researcher Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
1997/01/01 - 2002/01/10 PhD in Biomedical Sciences Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1997/01/01 - 2000/12/31 PhD student (grant: PRAXIS XXI/BD/9305/96) Supervisor: Claudio Sunkel Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
1998/09/15 - 1998/12/15 Visiting PhD student, Supervisor: Caetano Gonzalez European Molecular Biology Laboratory, Germany
1995/01/01 - 1996/12/31 Graduate student (grant: PRAXIS XXI/4/4.1/BIC 904) Supervisor: Claudio Sunkel Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
1993/10/01 - 1994/09/19 Undergraduate student (last year graduation project) Supervisor: Claudio Sunkel Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Projects

Grant

Designation Funders
2022/01/01 - 2024/12/31 Small-molecule inhibition of genomic instability-driven senescence in Down Syndrome
2094-LE2021B
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fondation Jérôme Lejeune
Ongoing
2021/02/01 - 2024/09/30 Small-molecule modulation of aging-associated DNA damage and epigenetic erosion
PTDC/MED-OUT/2747/2020
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/12/31 - 2023/12/31 Excellence Hub on Phase Transitions in Aging and Age-Related Disorders - PhasAGE - H2020-WIDESPREAD-2020-5
952334
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 European Commission
Concluded
2022/01/01 - 2023/06/30 AGEAGENT- Feedback regulation behind age-associated cell cycle slow down as a potential anti-aging target
EXPL/BIA-CEL/0446/2021
Co-Principal Investigator (Co-PI)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2020/09/01 - 2023/06/30 HAIRCULES - Estratégias de regeneração do folículo capilar para tratamento de alopecia humana (EUR 641 822,47)
70201
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Saúde Viável SA, Portugal
Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização
Concluded
2021/03/01 - 2023/02/28 CANCER THERAPY - Cancer research on therapy resistance: from basic mechanisms to novel targets
CCDRN-2021-FEDER-000051
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2020/08/01 - 2022/07/31 Small-molecule enhancement of chromosomal stability as senotherapeutic strategy for HGPS
PRF 2020-78
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Progeria Research Foundation
Concluded
2018/07/26 - 2021/07/25 AGELeSS:In vivo amelioration of AGE-associated haLlmarkS by tranScriptional modulation
PTDC/BIA-CEL/31120/2017
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/07/01 - 2020/06/30 Effects of human ageing and aneuploidy in mitotic fitness and chromosome stability
IF/00916/2014
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/05 - 2019/12 Advanced cancer research: from basic knowledge to application
NORTE-01-0145-FEDER-000029
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 European Regional Development Fund
Concluded
2016/06/15 - 2019/10/30 Ageing: cells losing their mitotic fitness and chromosome balance
PTDC/BEX-BCM/2090/2014
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/07 - 2015/06 Cell homeostasis, tissue organization and organism biology
NORTE-07-0124-FEDER-000003
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Programa Operacional Regional do Norte (ON.2)/QREN
Concluded
2011 - 2015 PRECISE - Spatiotemporal regulation of chromosome segregation fidelity
260892
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 European Research Council
Concluded
2010/05/05 - 2013/10/30 Dissecting the cross-talk between mitotic checkpoint, ageing and cancer: towards the understanding of cell fate after mitotic slippage
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/100261/PT
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/09 Ataxin-3: gain and loss of function in Machado-Joseph disease
101572
Provided by PTCRIS: 101572
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010/05 - 2013/04 Functional dissection of mitotic spindle assembly pathways by comparative genomics
99704
Provided by PTCRIS: 99704
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2004/01/01 - 2007/12/31 Genes Involved in The Mitotic Checkpoint in Drosophila melanogaster
POCTI/BCI/42341/2001
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/01/02 - 2004/01/01 Genetic and molecular analysis of proteins required for the organization and function of the mitotic apparatus
POCTI/BME/35187/2000
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2011/01/01 - 2012/12/31 Strategic Project - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2017/01/01 - 2019/12/31 Impact of storage conditions used during hair follicle unit extraction (FUE) in dermal papilla cell stemness
NA
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Saúde Viável, Lda
Concluded
2005/10/01 - 2006/09/30 Analysis of molecular mechanisms that coordinate microtubule-kinetochore interactions with spindle checkpoint signaling
1F/06/CESPU/2006
Principal investigator
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
2005/10/01 - 2006/09/30 Chromosome instability associated with Bub3 gene silencing in human cells: a functional analysis
1F/08/CESPU/2006
Principal investigator
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
 Cooperativa de Ensino Superior Politécnico e Universitário
Concluded
Outputs

Publications

Book chapter
  1. Macedo, Joana Catarina; Vaz, Sara; Logarinho, Elsa. "Mitotic Dysfunction Associated with Aging Hallmarks". In Advances in Experimental Medicine and Biology, 153-188. Springer International Publishing, 2017.
    10.1007/978-3-319-57127-0_7
Conference abstract
  1. Mendes-da-Silva, Maria; Sousa-Soares, Carlos; Macedo, Joana Catarina; Logarinho, Elsa. "Improvement of aging hallmarks through mitotic epigenetic bookmarking". Paper presented in 16th IJUP, Porto, 2023.
    Published
  2. Lima, Vera; Macedo, J; Pinheiro, D; Alves, C; Castedo, S; Barros, Alberto; Maiato, H; Dória, S; Logarinho, Elsa. "Dissecting a link between aneuploidy and chromosome instability in humans. Chromosome". Paper presented in European Cytogenetics Conference, 2013.
    Published
Conference paper
  1. Mesquita, A.; Silva, Alexandra; Sampaio-Marques, B.; Almeida, Bruno; Logarinho, Elsa; Leão C; Rodrigues F; Ludovico P. "Oxidative stress during chronological life span in Saccharomyces cerevisiae". Paper presented in MicroBiotec 09, 2009.
    Published
Conference poster
  1. Lucas, Diogo; Silvério, Diogo; Soares, Carlos; Vieira, Paulo; Saraiva, Margarida; Logarinho, Elsa. "FOXM1 induction as hematopoietic aging targeting therapy". Paper presented in 6th PhDay, 2023.
  2. Sousa-Soares, Carlos; Mendes-da-Silva, Maria; Macedo, Joana Catarina; Logarinho, Elsa. "Defective H3K9me2-mediated heterochromatin bookmarking in aging". Paper presented in 6th PhDay, 2023.
  3. Araujo, Ana Rita; Gaspar-Silva, Filipa; Logarinho, Elsa. "The fundamental principles of cell cycle control: what goes wrong with aging?". Paper presented in The cell cycle: One engine - many cycles, 2022.
  4. Ferreira, Fábio J.; Galhardo, Mafalda; Logarinho, Elsa; Bessa, José. Corresponding author: Bessa, José. "The FOXM1/AP-1 axis: an enhancer hub at the center of chromatin accessibility in senescence". Paper presented in 7th International Cell Senescence Association (ICSA) Conference, Groningen, The Netherlands, 2022.
  5. Ferreira, Fábio J.; Teixeira, Joana; Galhardo, Mafalda; Logarinho, Elsa; Bessa, José. Corresponding author: Bessa, José. "The impact of chromatin accessibility in aging-associated transcriptional profiles". Paper presented in 19th Portugaliæ Genetica - Phenotypic Manifestation of Genetic Heterogeneity, 2022.
  6. Monteiro, Luís; Pitrez, Patricia R.; Correia-Santos, Simão; Nicola Dark; Deolinda Santinha; Xavier, Nissan; Sardão, Vilma; et al. Corresponding author: Monteiro, Luís. "Disease modeling and drug screening on cardiomyocytes derived from Hutchinson-Gilford Progeria Syndrome- induced pluripotent stem cells". Paper presented in The Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), 2022.
  7. Lopes, Danilo; Orr, Bernardo; Bettencourt-Dias, Mónica; Logarinho, Elsa; Maiato, Helder. "The role of tubulin post-translational modifications in human cancers and during aging". Paper presented in II PGCD PhD Students Meeting, 2017.
  8. Ferreira, Daniela; Silva, Teresa; Gomes-Alves, Ana; Rodrigues, Ana-João; Chaves, Raquel; Logarinho, Elsa. "Human centrosomal protein Cep57 is required for proper mitotic spindle structure". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010.
Journal article
  1. Ana Rita Castro; Carlos Portinha; Elsa Logarinho. "The booming business of hair loss". Trends in Biotechnology (2023): https://doi.org/10.1016/j.tibtech.2022.12.020.
    10.1016/j.tibtech.2022.12.020
  2. Ana Rita Castro; Carlos Portinha; Elsa Logarinho. "The Emergent Power of Human Cellular vs Mouse Models in Translational Hair Research". Stem Cells Translational Medicine (2022): https://doi.org/10.1093/stcltm/szac059.
    10.1093/stcltm/szac059
  3. Ribeiro, Rui; Macedo, Joana C.; Costa, Madalena; Ustiyan, Vladimir; Shindyapina, Anastasia V.; Tyshkovskiy, Alexander; Gomes, Rita N.; et al. "In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan". Nature Aging 2 5 (2022): 397-411. http://dx.doi.org/10.1038/s43587-022-00209-9.
    Published • 10.1038/s43587-022-00209-9
  4. Sara Vaz; Fábio J. Ferreira; Joana C. Macedo; Gil Leor; Uri Ben-David; José Bessa; Elsa Logarinho. "FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation". Cell Death & Disease (2021): https://doi.org/10.1038/s41419-021-03822-5.
    10.1038/s41419-021-03822-5
  5. Fábio J. Ferreira; Leonor Carvalho; Elsa Logarinho; José Bessa. "foxm1 Modulates Cell Non-Autonomous Response in Zebrafish Skeletal Muscle Homeostasis". Cells 10 5 (2021): 1241-1241. https://doi.org/10.3390/cells10051241.
    10.3390/cells10051241
  6. Siranjeevi Nagaraj; Andrew Want; Katarzyna Laskowska-Kaszub; Aleksandra Fesiuk; Sara Vaz; Elsa Logarinho; Urszula Wojda. "Candidate Alzheimer’s Disease Biomarker miR-483-5p Lowers TAU Phosphorylation by Direct ERK1/2 Repression". International Journal of Molecular Sciences 22 7 (2021): 3653-3653. https://doi.org/10.3390/ijms22073653.
    Published • 10.3390/ijms22073653
  7. Ferreira, Luísa T.; Logarinho, Elsa; Macedo, Joana C.; Maia, Ana Rita R.; Maiato, Helder. "SOGA1 and SOGA2/MTCL1 are CLASP-interacting proteins required for faithful chromosome segregation in human cells". Chromosome Research (2021): http://dx.doi.org/10.1007/s10577-021-09651-8.
    Published • 10.1007/s10577-021-09651-8
  8. Barroso-Vilares, Monika; Macedo, Joana C; Reis, Marta; Warren, Jessica D; Compton, Duane; Logarinho, Elsa. "Small-molecule inhibition of aging-associated chromosomal instability delays cellular senescence". EMBO reports (2020): http://dx.doi.org/10.15252/embr.201949248.
    Published • 10.15252/embr.201949248
  9. Castro, Ana Rita; Logarinho, Elsa. "Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal? Concise review". STEM CELLS Translational Medicine (2019): http://dx.doi.org/10.1002/sctm.19-0301.
    Open access • Published • 10.1002/sctm.19-0301
  10. Castro, Ana Rita; Portinha, Carlos; Logarinho, Elsa. "Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression". Dermatologic Surgery 45 12 (2019): 1649-1659. http://dx.doi.org/10.1097/dss.0000000000001895.
    Published • 10.1097/dss.0000000000001895
  11. Barroso-Vilares, Monika; Logarinho, Elsa. "Chromosomal instability and pro-inflammatory response in aging". Mechanisms of Ageing and Development 182 (2019): 111118. http://dx.doi.org/10.1016/j.mad.2019.111118.
    Published • 10.1016/j.mad.2019.111118
  12. Nellikka, Rohith Kumar; Sreeja, Jamuna S.; Dharmapal, Dhrishya; John, Rince; Monteiro, Augusta; Macedo, Joana Catarina; Conde, Carlos; et al. "a-Fodrin is required for the organization of functional microtubules during mitosis". Cell Cycle 18 20 (2019): 2713-2726. http://dx.doi.org/10.1080/15384101.2019.1656476.
    Published • 10.1080/15384101.2019.1656476
  13. Shukla, Samriddhi; Milewski, David; Pradhan, Arun; Rama, Nihar; Rice, Kathryn; Le, Tien; Flick, Matthew J.; et al. "The FOXM1 Inhibitor RCM-1 Decreases Carcinogenesis and Nuclear ß-Catenin". Molecular Cancer Therapeutics 18 7 (2019): 1217-1229. http://dx.doi.org/10.1158/1535-7163.mct-18-0709.
    10.1158/1535-7163.mct-18-0709
  14. Pinho, Marta; Macedo, Joana C.; Logarinho, Elsa; Pereira, Paulo S.. "NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging". Molecular and Cellular Biology 39 12 (2019): http://dx.doi.org/10.1128/mcb.00099-19.
    Open access • Published • 10.1128/mcb.00099-19
  15. Melo Pereira, Sofia; Ribeiro, Rui; Logarinho, Elsa. "Approaches towards Longevity: Reprogramming, Senolysis, and Improved Mitotic Competence as Anti-Aging Therapies". International Journal of Molecular Sciences 20 4 (2019): 938. http://dx.doi.org/10.3390/ijms20040938.
    Open access • Published • 10.3390/ijms20040938
  16. Ghazaryan, Narine; Movsisyan, Naira; Macedo, Joana Catarina; Vaz, Sara; Ayvazyan, Naira; Pardo, Luis; Logarinho, Elsa. "The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model". Investigational New Drugs 37 5 (2019): 1044-1051. http://dx.doi.org/10.1007/s10637-019-00734-2.
    10.1007/s10637-019-00734-2
  17. Macedo, Joana Catarina; Vaz, Sara; Bakker, Bjorn; Ribeiro, Rui; Bakker, Petra Lammigje; Escandell, Jose Miguel; Ferreira, Miguel Godinho; et al. "FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence". Nature Communications 9 1 (2018): http://dx.doi.org/10.1038/s41467-018-05258-6.
    10.1038/s41467-018-05258-6
  18. Cimino, M.; Gonçalves, R.M.; Bauman, E.; Barroso-Vilares, M.; Logarinho, E.; Barrias, C.C.; Martins, M.C.L.. "Optimization of the use of a pharmaceutical grade xeno-free medium for in vitro expansion of human mesenchymal stem/stromal cells". Journal of Tissue Engineering and Regenerative Medicine 12 3 (2017): e1785-e1795. http://dx.doi.org/10.1002/term.2588.
    10.1002/term.2588
  19. Rutledge, Samuel D.; Douglas, Temple A.; Nicholson, Joshua M.; Vila-Casadesús, Maria; Kantzler, Courtney L.; Wangsa, Darawalee; Barroso-Vilares, Monika; et al. "Selective advantage of trisomic human cells cultured in non-standard conditions". Scientific Reports 6 1 (2016): http://dx.doi.org/10.1038/srep22828.
    10.1038/srep22828
  20. Nicholson, Joshua M; Macedo, Joana C; Mattingly, Aaron J; Wangsa, Darawalee; Camps, Jordi; Lima, Vera; Gomes, Ana M; et al. "Chromosome mis-segregation and cytokinesis failure in trisomic human cells". eLife 4 MAY (2015): http://dx.doi.org/10.7554/elife.05068.
    10.7554/elife.05068
  21. Neves-Carvalho, Andreia; Logarinho, Elsa; Freitas, Ana; Duarte-Silva, Sara; Costa, Maria do Carmo; Silva-Fernandes, Anabela; Martins, Margarida; et al. "Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells". Human Molecular Genetics 24 1 (2014): 100-117. http://dx.doi.org/10.1093/hmg/ddu422.
    10.1093/hmg/ddu422
  22. Maiato, Helder; Logarinho, Elsa. "Mitotic spindle multipolarity without centrosome amplification". Nature Cell Biology 16 5 (2014): 386-394. http://dx.doi.org/10.1038/ncb2958.
    10.1038/ncb2958
  23. Schweizer, Nina; Ferrás, Cristina; Kern, David M.; Logarinho, Elsa; Cheeseman, Iain M.; Maiato, Helder. "Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis". Journal of Cell Biology 203 6 (2013): 883-893. http://dx.doi.org/10.1083/jcb.201309076.
    10.1083/jcb.201309076
  24. Logarinho, Elsa; Maffini, Stefano; Barisic, Marin; Marques, Andrea; Toso, Alberto; Meraldi, Patrick; Maiato, Helder. "CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment". Nature Cell Biology 14 3 (2012): 295-303. http://dx.doi.org/10.1038/ncb2423.
    Published • 10.1038/ncb2423
  25. Maiato, Helder; Logarinho, Elsa. "Motor-Dependent and -Independent Roles of CENP-E at Kinetochores: The Cautionary Tale of UA62784". Chemistry & Biology 18 6 (2011): 679-680. http://dx.doi.org/10.1016/j.chembiol.2011.06.002.
    Published • 10.1016/j.chembiol.2011.06.002
  26. Rodrigues, Ana João; Neves-Carvalho, Andreia; Teixeira-Castro, Andreia; Rokka, Anne; Corthals, Garry; Logarinho, Elsa; Maciel, Patrícia. "Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans". PLoS ONE 6 4 (2011): e18512. http://dx.doi.org/10.1371/journal.pone.0018512.
    10.1371/journal.pone.0018512
  27. Rodrigues, Ana-João; do Carmo Costa, Maria; Silva, Teresa-Luísa; Ferreira, Daniela; Bajanca, Fernanda; Logarinho, Elsa; Maciel, Patrícia. "Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1803 10 (2010): 1154-1163. http://dx.doi.org/10.1016/j.bbamcr.2010.07.004.
    10.1016/j.bbamcr.2010.07.004
  28. Costa, Maria do Carmo; Bajanca, Fernanda; Rodrigues, Ana-João; Tomé, Ricardo J.; Corthals, Garry; Macedo-Ribeiro, Sandra; Paulson, Henry L.; Logarinho, Elsa; Maciel, Patrícia. "Ataxin-3 Plays a Role in Mouse Myogenic Differentiation through Regulation of Integrin Subunit Levels". PLoS ONE 5 7 (2010): e11728. http://dx.doi.org/10.1371/journal.pone.0011728.
    Open access • Published • 10.1371/journal.pone.0011728
  29. Torrado, Egídio; Fraga, Alexandra G.; Logarinho, Elsa; Martins, Teresa G.; Carmona, Jenny A.; Gama, José B.; Carvalho, Maria A.; et al. "IFN-¿–Dependent Activation of Macrophages during Experimental Infections by Mycobacterium ulcerans Is Impaired by the Toxin Mycolactone". The Journal of Immunology 184 2 (2009): 947-955. http://dx.doi.org/10.4049/jimmunol.0902717.
    Open access • Published • 10.4049/jimmunol.0902717
  30. Almeida, A.J.; Cunha, C.; Carmona, J.A.; Sampaio-Marques, B.; Carvalho, A.; Malavazi, I.; Steensma, H.Y.; et al. "Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis". Fungal Genetics and Biology 46 12 (2009): 919-926. http://dx.doi.org/10.1016/j.fgb.2009.08.004.
    Published • 10.1016/j.fgb.2009.08.004
  31. Rodrigues, Ana-João; Neves-Carvalho, Andreia; Ferro, Anabela; Rokka, Anne; Corthals, Garry; Logarinho, Elsa; Maciel, Patrícia. "ATX-3, CDC-48 and UBXN-5: A new trimolecular complex in Caenorhabditis elegans". Biochemical and Biophysical Research Communications 386 4 (2009): 575-581. http://dx.doi.org/10.1016/j.bbrc.2009.06.092.
    Published • 10.1016/j.bbrc.2009.06.092
  32. Logarinho, E.; Bousbaa, H.. "Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1: The dual task of attaching and signalling". Cell Cycle 7 12 (2008): 1763-1768. http://www.scopus.com/inward/record.url?eid=2-s2.0-47249113044&partnerID=MN8TOARS.
    10.4161/cc.7.12.6180
  33. Logarinho, E.; Resende, T.; Torres, C.; Bousbaa, H.. "The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments". Molecular Biology of the Cell 19 4 (2008): 1798-1813. http://www.scopus.com/inward/record.url?eid=2-s2.0-44949185572&partnerID=MN8TOARS.
    10.1091/mbc.E07-07-0633
  34. Ferro, Anabela; Carvalho, Ana Luísa; Teixeira-Castro, Andreia; Almeida, Carla; Tomé, Ricardo J.; Cortes, Luísa; Rodrigues, Ana-João; et al. "NEDD8: A new ataxin-3 interactor". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773 11 (2007): 1619-1627. http://dx.doi.org/10.1016/j.bbamcr.2007.07.012.
    Open access • Published • 10.1016/j.bbamcr.2007.07.012
  35. Logarinho, Elsa; Bousbaa, Hassan; Dias, José Miguel; Lopes, Carla; Amorim, Isabel; Antunes-Martins, Ana; Sunkel, Claudio E.. "Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores inDrosophilacells". Journal of Cell Science 117 9 (2004): 1757-1771. http://dx.doi.org/10.1242/jcs.01033.
    Open access • Published • 10.1242/jcs.01033
  36. Cambiazo, Verónica; Logarinho, Elsa; Pottstock, Hans; Sunkel, Claudio E; Cambiazo, V.; Logarinho, E.; Pottstock, H.; Sunkel, C.E.. "Microtubule binding of the Drosophila DMAP-85 protein is regulated by phosphorylation in vitro". FEBS Letters 483 1 (2000): 37-42. http://dx.doi.org/10.1016/s0014-5793(00)02077-9.
    Open access • Published • 10.1016/s0014-5793(00)02077-9
  37. Perdigao, Joana; Logarinho, Elsa; Avides, Maria C.; Sunkel, Claudio E.. "Molecular Cloning, Developmental Expression, and Cellular Localization of the 70-kDa RPA-1 Subunit of Drosophila melanogaster". DNA and Cell Biology 18 12 (1999): 923-936. http://dx.doi.org/10.1089/104454999314782.
    Published • 10.1089/104454999314782
  38. Basu, Joydeep; Bousbaa, Hassan; Logarinho, Elsa; Li, ZeXiao; Williams, Byron C.; Lopes, Carla; Sunkel, Claudio E.; Goldberg, Michael L.. "Mutations in the Essential Spindle Checkpoint Gene bub1 Cause Chromosome Missegregation and Fail to Block Apoptosis in Drosophila". The Journal of Cell Biology 146 1 (1999): 13-28. http://dx.doi.org/10.1083/jcb.146.1.13.
    Open access • Published • 10.1083/jcb.146.1.13
  39. Basu, Joydeep; Logarinho, Elsa; Herrmann, Siegrun; Bousbaa, Hassan; Li, ZeXiao; Chan, Gordon K. T.; Yen, Tim J.; Sunkel, Claudio E.; Goldberg, Michael L.. "Localization of the Drosophila checkpoint control protein Bub3 to the kinetochore requires Bub1 but not Zw10 or Rod". Chromosoma 107 6-7 (1998): 376-385. http://dx.doi.org/10.1007/s004120050321.
    Published • 10.1007/s004120050321
  40. Logarinho, E.; Sunkel, C.E.; Logarinho, Elsa; Claudio E. Sunkel; Santos, J.A.; Tapia, C.; Allende, C.C.; Allende, J.E.. "The Drosophila POLO kinase localises to multiple compartments of the mitotic apparatus and is required for the phosphorylation of MPM2 reactive epitopes". Journal of Cell Science 111 19 (1998): 2897-2909. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031790268&partnerID=MN8TOARS.
    Published
Preprint
  1. Fábio J. Ferreira; Mafalda Galhardo; Joana Teixeira; Elsa Logarinho; José Bessa. "FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1". 2023. https://doi.org/10.1101/2023.05.04.539315.
    10.1101/2023.05.04.539315
Thesis / Dissertation
  1. Logarinho, Elsa. "Cell cycle regulation in Drosophila melanogaster". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2002.

Intellectual property

Patent
  1. Logarinho, Elsa. 2023. "Galunisertib for use in the treatment of androgenic alopecia". Portugal.
    Allowed
  2. Logarinho, Elsa. 2021. "4-PYRROLIDIN-1-YL-5-P-TOLYL-THIENO[2,3-D] PYRIMIDINE FOR USE IN THE TREATMENT OF AGING-ASSOCIATED AND PREMATURE AGING DISEASES THROUGH RESTORED CHROMOSOMAL STABILITY AND INHIBITION OF CELLULAR SENESCENCE". Portugal.
    Allowed
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/02/23 Invited speaker. Healthspan extension in progeroid and naturally aged mice by an extra copy of the FOXM1 gene. IEO Seminars, Milan. IEO Seminars
European Institute of Oncology (IEO) (Milan, Italy)
2023/12/07 Invited speaker. Title: Lifespan extension by an extra copy of the FOXM1 gene. 3rd RESETageing conference, Coimbra, PT, 6-7 December 2023 3rd RESETageing conference
Multidisciplinary Institute in Ageing, University of Coimbra (Coimbra, Portugal)
2023/09/04 Pharmacological inhibition of microtubule-driven genotoxic stress in progeroid syndromes GROUP LEADER SEMINAR @ i3S
Instituto de Investigação e Inovação em Saúde (porto, Portugal)
2023/07/12 Invited speaker. Title: Healthspan extension in progeroid and naturally aged mice by an extra copy of the FOXM1 gene Institut Curie Seminar series
Institut Curie (Paris, France)
2023/06/18 Selected talk. Pharmacologic inhibition of TGFß signaling improves human hair follicle growth cycle 20th Meeting of the European Hair research society (EHRS)
European Hair Research Society (Sheffield, United Kingdom)
2023/06/02 Invited speaker. Title: Healthspan extension in progeroid and naturally aged mice by an extra copy of the FOXM1 gene CIMUS Seminar series
CIMUS - Centro Singular de Investigacion en Medicina Molecular e Enfermidades Crónicas (Santiago de Compostela, Spain)
2023/03/24 Invited speaker. Title: New senotherapies against aging and progeroid syndromes ERIBA Seminar Series
ERIBA - UMCG (Groningen, Netherlands)
2022/12/06 Invited speaker. New senotherapies against aging and progeroid syndromes Ageing without borders (https://awbfaro2022.wixsite.com/website)
Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC) (Faro, Portugal)
2022/11/18 Invited speaker. Induction of the transcription factor FOXM1 drives health span extension in progeroid and naturally aged mice https://skin-challenges.com/wp-content/uploads/dlm_uploads/2022/11/Skin_2022_Agenda_V36.pdf 13th International Conference Skin Ageing Challenges
International Society of Microbiota (Lisbon, Portugal)
2022/11/11 Selected talk. Small-molecule targeting of microtubule-driven genotoxic stress in progeroid syndromes The Consequences of Aneuploidy Conference: Honoring the Contributions of Angelika Amon
FASEB Science Research Conference (Southbridge, United States)
2022/11/04 Invited speaker. Small-Molecule Correction of Microtubule-Dependent Genotoxic Stress in HGPS Cells Bypasses Progerin-Driven Cellular Phenotypes The PRF 11th International Scientific Workshop
Progeria Research Foundation (Boston, United States)
2022/10/29 Selected talk. Pharmacological therapy improving hair follicle growth 30th World Congress of the ISHRS (International Society of HairRestoration)
International Society of Hair Restoration (City of Panama, Panama)
2022/04/18 Biomolecular condensates and aging hallmarks PhaseAGE Training School - Biomolecular condensates in cell function, aging and disease
i3S- Instituto de Investigação e Inovação em Saúde (Porto, Portugal)
2021/08/28 Inhibition of age-associated CIN: emerging strategy to delay cellular senescence and aging ESHG 2021 Session E16.1 Chromosomal Instability and Aging European Society Human Genetics 2021 Virtual Conference
European Society of Human Genetics
2021/06/14 Inhibition of age-associated genomic instability: emerging strategy to delay cellular senescence and aging The Widespread - Twinning project PhasAGE - 2nd seminar of the PhasAGE Expert Seminar Series
https://phasage.eu/ess/ (Portugal)
2021/05/27 Life- and healthspan extension by FoxM1 transcriptional activity rewire GROUP LEADER SEMINAR @ i3S
i3S (Portugal)
2021/03/30 Keynote speaker. Inhibition of age-associated CIN: emerging strategy to delay cellular senescence and aging Ageing Webinar
Sociedade Portuguesa de Bioquímica (Portugal)
2020/11/24 Invited speaker. A close look into cellular aging SPAOM 2020 - Spanish & Portuguese Advanced Optical Microscopy Meeting
2020/07/16 Invited speaker. Inhibition of age-associated CIN: emerging strategy to delay cellular senescence and aging Aneuploidy and Chromosomal Instability Zoom Forum, CSHL Aneuploidy and Chromosomal Instability Zoom Forum
Cold Spring Harbour Laboratories
2019/11/27 Invited speaker. Improvement of aging hallmarks by mitotic competence rewire CNC Seminars, Centro de Neurociências e Biologia Celular, Universidade de Coimbra
(Coimbra, Portugal)
2019/11/14 Invited speaker. AgeLess: Improving proliferative capacity towards rejuvenation The III International Congress in Health Sciences Research: Trends in Aging and Cancer, 14-16 Nov
CICS-UBI (Covilhã, Portugal)
2019/11 Selected talk. Impact of distinct preservation solutions on hair micrografts viability ascertained by dermal papilla gene expression. Castro, AR, Portinha C, Logarinho E. 27th World Congress and World Live Surgery Workshop of the International Society of Hair Restoration Surgery (ISHRS)
International Society of Hair Restoration Surgery (ISHRS) (Bangkok, Thailand)
2019/05/13 Invited speaker. Inhibition of age-associated CIN: emerging strategy to delay cellular senescence and aging EMBO Workshop Chromosome segregation and aneuploidy
(Cascais, Portugal)
2019/03/22 Invited speaker. Elsa Logarinho and the Aging & Aneuploidy Lab V Semana de Bioengenharia IST, Instituto Superior Técnico
(Lisboa, Portugal)
2018/12/05 Invited speaker. Chromosomal instability and proinflammatory response in aging and cancer The Symposia on Tumour Biology: from basic biology to disease (ReTuBi), December 5-6
(Lisbon, Portugal)
2018/06/26 Selected talk. FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence 10th Salk Institute Cell Cycle Meeting, 26-29 June
(La Jolla, United States)
2018/05/07 Selected talk. Molecular basis of mitotic decline and aneuploidy-driven senescence during human aging Molecular, Cellular and Organismal Hallmarks of Aging - Cnio La Caixa Foundation Frontiers Meetings, 7-9 May
(Madrid, Spain)
2018/05 Selected talk. Impact of distinct preservation solutions on hair micrografts viability ascertained by dermal papilla gene expression signature. Castro, AR, Portinha C, Logarinho E. 18th Meeting of the European Hair research society (EHRS)
European Hair Research Society (EHRS) (Bologna, Italy)
2018/03/22 Invited speaker. The feedback loop between aging and aneuploidy 18th Portugaliæ Genetica: Genetic Diversity in Structure and Regulation, 22 & 23 March, i3S
(Porto, Portugal)
2017/10/08 Selected talk. Getting older from an old mitosis: molecular basis of mitotic decline during human aging 2nd Meeting on the Molecular Biology of Ageing, ERIBA, 8-11 October
(Groningen, Netherlands)
2017/05/11 Invited speaker. Getting older from an old mitosis Tohoku Forum for Creativity Conference in Aging Biology, 10-12 May
(Tohoku, Japan)
2016/11/17 Invited speaker. Anti-mitotic drugs in cancer chemotherapy: age matters Simpósio Nacional da Sociedade Portuguesa de Oncologia
(Espinho, Portugal)
2016/11 Old cells' division: the crosstalk between aging and aneuploidy i3S Annual Meeting
(Póvoa de Varzim, Portugal)
2016/09/30 Invited speaker. Old cells' division: the crosstalk between aging and aneuploidy 1st Symposium on Aging Research- Molecular mechanisms of aging and age-related diseases, CNC, University of Coimbra
(Coimbra, Portugal)
2016/06/25 Selected talk. Mitotic function decline leads to aneuploidy and senescence during natural aging Embo Workshop in Chromosome Segregation and Aneuploidy, 25-29 June 2016
(Galway, Ireland)
2015/12/04 Invited speaker. Loss of mitotic fitness during human ageing CNC Seminars, Center for Neuroscience and Cell Biology, University of Coimbra
(Coimbra, Portugal)
2014/11/21 Invited speaker. Mitotic fitness: a matter of age and chromosome balance IGC Seminars, Instituto Gulbenkian da Ciência
(Oeiras, Portugal)
2014/10/18 Keynote speaker. Divisão celular: implicações para a vida e a doença Tertúlia "De Matosinhos para o mundo... uma conversa com a ciência"
Associação de Matosinhos do Passado ao Futuro (Matosinhos, Portugal)
2012/12 Invited speaker. Ageing and Aneuploidy: 'CINful' ways? 50th American Society for Cell Biology Annual Meeting
(San Francisco, United States)
2012/09 Invited speaker. Ser Cientista... 30º Encontro Juvenil de Ciência, Universidade do Porto, 1-8 Setembro
(Porto, Portugal)
2011/06/15 Selected talk. CLASPs ensure spindle pole integrity in response to kinetochore traction forces 2nd Dynamic Kinetochore Workshop, 15-18 June, IMP Vienna
(Vienna, Austria)
2011 Invited speaker. CLASPs ensure spindle pole integrity in response to kinetochore traction forces I3S Annual Meeting
(Póvoa de Varzim, Portugal)
2010/12/06 Invited speaker. CLASPs role in mitotic spindle integrity International Workshop "Genotoxic Effects of Terahertz radiation in vitro", 6-7 December 2010, Physikalisch-Technische Bundsanstalt
(Braunschweig, Germany)
2009 Invited speaker. Kinetochore-microtubule interactions, mitotic checkpoint and chromosome segregation fidelity EMBL Alumni Association- Iberian Local Chapter Meeting, IBMC, Porto
(Porto, Portugal)
1998 Selected talk. Immunolocalisation of the mitotic kinase POLO and its involvement in generating MPM2 reactive epitopes in Drosophila 4th International Meeting of Chromosome Segregation and Aneuploidy
(Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/01/01 - Current PhD supervision. Title: FOXM1 induction as immunosenescence targeting therapy
Supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/01/01 - Current PhD supervision. Title: Therapeutic targeting of aging-associated epigenetic erosion
Supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/11/01 - Current Post-doc supervision (Assistant Researcher 2022.00872.CEECIND) . Title: The role of pro-inflammatory Aged Clonal B Cells in peripheral tissues’ age-related dysfunction
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/12/01 - Current Post-doc supervision (Assistant Researcher). Title: Human hair follicle regeneration - from molecular mechanisms to therapeutic targeting.
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Saúde Viável SA, Portugal
2021/09/01 - Current Post-doc supervision (Assistant Researcher). Title: Human hair follicle regeneration - from molecular mechanisms to therapeutic targeting.
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Saúde Viável SA, Portugal
2020/08/01 - Current Post-doc supervision (Junior Researcher). Title: Small-molecule modulation of aging-associated DNA damage and epigenetic erosion
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/06/01 - Current Post-Doc supervision (Junior Researcher CEEC 2019). Title: Feedback regulation of cell cycle dynamics during aging
Supervisor
 Junior Investigator CEEC2019 (Other)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/02/01 - 2023/10/31 Post-doc supervision (Junior Researcher). Title: Human hair follicle regeneration - from molecular mechanisms to therapeutic targeting.
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Saúde Viável SA, Portugal
2022/09/01 - 2023/09/15 MSc supervision. Title: Improvement of aging hallmarks through mitotic epigenetic bookmarking
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/09/01 - 2023/09/15 MSc supervision. Title: In vivo reversion of progeria phenotypes by cyclic induction of the FOXM1 transcription factor
Co-supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023/03/01 - 2023/07/05 BSc project. Title: In vivo reversion of progeria phenotypes by an extra copy of the FOXM1 gene
Supervisor
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2022/09/01 - 2023/06/27 MSc Thesis. Title: The fundamental principles of cell cycle control: what goes wrong with aging?
Supervisor
 Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2023/01/06 PhD thesis. Title: Human hair follicle regeneration - from molecular mechanisms to therapeutic targeting.
Supervisor
 Engenharia Biomédica (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
2021/09 - 2022/12/14 MSc Thesis. Title: Feedback regulation behind age-associated cell cycle slow down as a potential anti-aging target
Supervisor
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2021/09/01 - 2022/11/24 MSc Thesis. Title: Investigating the functional relevance of FoxM1 isoforms and truncated forms in breast cancer cell tumorigenesis.
Co-supervisor of Komal Khalil
 Oncologia (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/10/01 - 2022/04/04 PhD Thesis. title: Mechanistic insights into age-associated chromosomal instability and senescence
Supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2022/03/21 PhD Thesis. Title: Forever young¿ - Targeting cellular senescence for healthspan and lifespan extension
Supervisor
 Doctoral Program in Areas of Basic and Applied Biology - FCT PhD program (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2022/01/11 PhD Thesis. Title: Transcriptional cis regulation of FOXM1 during aging
Supervisor
 Doctoral Program in Areas of Basic and Applied Biology (GABBA), FCT PhD Program (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2021/07/09 PhD Thesis. title: Age-dependent sensitivity to anti-mitotics: the role of FoxM1 and its therapeutic potential
Supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09/01 - 2021/03/18 MSc Thesis. Title: Improvement of Trisomy 21 cellular fitness with senolytic drug treatments
Supervisor
 Investigação Biomédica (Master)
Universidade Nova de Lisboa, Portugal
2015 - 2020/09/28 PhD Thesis. title: The role of Nol12 in nucleolar homeostasis and its impact in ribosomal stress, aging and chromosomal instability
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - 2019 BSc Project. Title: Molecular mechanisms behind chromosomal instability-driven pro-inflammatory response during aging
Supervisor
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2013 - 2018/10/09 PhD Thesis. Title: Mitotic fidelity: the feedback regulatory loop between aneuploidy and aging.
Supervisor
 Biomedicina (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2018 BIM fellowship. Title: Adaptive potential of aneuploidy in cancer
Supervisor
 BIM fellowship under the project NORTE-01-0145-FEDER-000029 (Scientific initiation)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012 - 2018 PhD Thesis. Title: Molecular and Functional Characterization of a satellite non-coding RNA ¿ FA-SAT - a key player in cycling cells
Co-supervisor
 Biological Sciences (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2015 - 2016 MSc Thesis. Title: Impact of aneuploidy-associated proteotoxic stress on chromosomal instability
Supervisor
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2015 - 2016 MSc Thesis. Title: Impact of human aneuploidy on chromosomal stability
Supervisor
 Bioengenharia (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2014 - 2015 MSc Thesis. Title: Effect of FoxM1 repression in the increased susceptibility to microtubule poisons
Supervisor
 Biologia Celular e Molecular (Master)
Universidade de Coimbra, Portugal
2014 - 2015 BI fellowship. Title: Regulation of the Vito/Nol12 nucleolar protein and its implications in cellular proliferation, growth and aging
Co-supervisor
 BI fellowship FCT (Scientific initiation)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2014 - 2015 BSc project. Title: Effects of human aneuploidy in mitotic fitness and chromosomal instability
Supervisor
 Biologia (Degree)
Universidade de Aveiro Departamento de Biologia, Portugal
2012 - 2013 BI fellowship. Title: Dissecting the cross-talk between mitotic checkpoint, aging and cancer: towards the understanding of cell fate after mitotic slippage
Supervisor
 BI fellowship under the FCT project PTDC/SAU-OBD/100261/2008 (Scientific initiation)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008 - 2012 PhD Thesis. Title: New insight into translation during yeast programmed cell death
Co-supervisor
 Health Sciences (PhD)
Universidade do Minho Escola de Medicina, Portugal
2010 - 2011 BI fellowship. Title: Dissecting the cross-talk between mitotic checkpoint, aging and cancer: towards the understanding of cell fate after mitotic slippage
Supervisor
 BI fellowship under the FCT project PTDC/SAU-OBD/100261/2008 (Scientific initiation)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008 - 2009 MSc Thesis. Title: Mitotic function of human Cep57 in the regulation of microtubule interactions with centrosomes and kinetochores
Supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2005 - 2008 PhD Thesis. Title: C. elegans ataxin-3: function, loss of function and molecular partners
Co-supervisor
 Health Sciences (PhD)
Universidade do Minho Escola de Medicina, Portugal
2004 - 2007 PhD Thesis, Title: Identification and characterization of ataxin-3 molecular interactors
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022/06/01 - 2022/11/11 i3S Annual Meeting 9th edition, Porto, >800 participants (2022/11/11 - 2022/11/11)
Meeting (Member of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/04 - 2022/04/24 The William Guy Forbeck Research Foundation Focus Meeting: Aneuploidy in cancer development, prognosis and treatment, Italy 21-24 April 2022 (Organization started in 2019; postponed to 2022 due to pandemics) (2022/04/21 - 2022/04/25)
Meeting (Co-organisor)
 The William Guy Forbeck Research Foundation, United States
2019/09 - 2022/03/25 19th Meeting Portugaliae Genetica - Phenotypic manifestation of genetic heterogeneity March 24-25 2022 (organization started in 2019; postponed to 2022 due to pandemics) (2022/03/24 - 2022/03/25)
Meeting (Member of the Scientific Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2009/01 - 2009/06 Post-graduation course entitled “Gene silencing using RNA interference: lectures and hands-on”. ICVS, Minho University, 30 hours. (2009/06/02 - 2009/06/05)
Workshop (Co-organisor)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2008/01 - 2008/06 Post-graduation course entitled “Gene silencing using RNA interference: lectures and hands-on”. ICVS, Minho University, 30 hours. (2008/06/02 - 2008/06/06)
Workshop (Co-organisor)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2008/01 - 2008/06 Post-graduation course entitled “Confocal Microscopy in Cell Biology“, IVCS, Minho University, 36 hours. (2008/06/16 - 2008/06/20)
Workshop (Co-organisor)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2007/01 - 2007/07/24 Workshop entitled “Live imaging in confocal microscopy”, ICVS, Minho University, 16 hours. (2007/07/23 - 2007/07/24)
Workshop (Co-organisor)
 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/10/27 - 2023/10/27 Invited Speaker. Congresso Maioridades - Cancro no envelhecimento. Mesa redonda sobre envelhecimento, doenças do envelhecimento (com destaque no cancro geriátrico), e estilo de vida para uma longevidade saudável. Produção Idioteque.
Round table
 Congresso Maioridades - Cancro no envelhecimento.
Misericórdia de Santo Tirso, Portugal
2023/06/14 - 2023/06/16 SELECTED TALK. Title: Pharmacologic inhibition of TGFß signaling improves human hair follicle growth cycle.
Meeting
 20th Meeting of the European Hair research society (EHRS)
European Hair Research Society, United Kingdom
2022/11/02 - 2022/11/04 INVITED SPEAKER. Small-Molecule Correction of Microtubule-Dependent Genotoxic Stress in HGPS Cells Bypasses Progerin-Driven Cellular Phenotypes.
Workshop
 The PRF 11th International Scientific Workshop
Progeria Research Foundation, United States
2022/10/27 - 2022/10/29 SELECTED TALK. Pharmacological therapy improving hair follicle growth.
Congress
 30th World Congress of the ISHRS (International Society of Hair Restoration and Surgery)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/09/11 - 2022/09/16 SELECTED TALK. Small-molecule targeting of microtubule-driven genotoxic stress in progeroid syndromes
Conference
 The consequences of Aneuploidy: Honoring the contributions of Angelika Amon
Federation of American Societies for Experimental Biology, United States
2022/05/01 - 2022/05/04 POSTER. Small-molecule correction of microtubule dynamics in progeria cells improves DNA DSB repair and bypasses progerin-driven phenotypes
Workshop
 Embo Workshop in Chromosome Segregation and Aneuploidy (meetings.embo.org/event/22-chromosome-segregation)
2021/12/18 - 2021/12/18 Invited expert for round table discussion "Extending your path: the science of longevity", Minho Medical Meeting 2021
Conference
 Minho Medical Meeting 2021
Universidade do Minho Escola de Medicina, Portugal
2020/02/12 - 2020/02/14 POSTER. Vaz S., Macedo J.C., Logarinho E., FoxM1 inhibition induces a pro-apoptotic gene signature in cancer cell anti-mitotic chemotherapy, 5th EACR Conference, Bergamo, Italy.
Conference
 5th EACR Conference, A Matter of Life or Death: Mechanisms, Models and Therapeutic Opportunities
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2020/02/12 - 2020/02/14 POSTER. Vaz S., Macedo J.C., Logarinho E., FoxM1 inhibition promotes mitotic cell death in response to spindle poison chemotherapy. 5th EACR Conference, Bergamo, Italy.
Conference
 5th EACR Conference, A Matter of Life or Death: Mechanisms, Models and Therapeutic Opportunities
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/11/10 - 2019/11/12 POSTER. Ribeiro R., Kalinichenko V., Logarinho E. Improvement of in vivo aging hallmarks through reestablishment of proliferative proficiency. 3rd Meeting on the Molecular Biology of Ageing. Groningen, The Netherlands.
Meeting
 3rd Meeting on the Molecular Biology of Ageing
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/10/28 - 2019/10/30 POSTER. Transcriptional cis regulation of FOXM1 during aging. Ferreira FJ, Teixeira J, Galhardo M, Logarinho E*, Bessa J*. Workshops “Current Trends in Biomedicine” - From Genes to Organisms: Transcriptional Control in Development and Disease, Baeza, Spain
Workshop
 Workshop From Genes to Organisms: Transcriptional Control in Development and Disease
2019/10/10 - 2019/10/12 POSTER. Barroso-Vilares M, Macedo JC, Reis M, Warren DC, Compton D, Logarinho E. Small molecule inhibition of aging-associated chromosomal instability delays cellular senescence. 3rd Meeting on the Molecular Biology of Ageing, Groningen, The Netherlands.
Meeting
 3rd Meeting on the Molecular Biology of Ageing. Groningen, The Netherlands (October 10-12, 2019)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/05/28 - 2019/05/28 Invited expert for round table discussion on longevity and fund savings. https://pt.fundspeople.com/news/sustentabilidade-da-seguranca-social-incentivos-a-poupanca-e-desafios-na-reforma
Round table
 Conferência “Longevidade e os Desafios da Poupança Após a Reforma”
Banco Bilbao Vizcaya Argentaria SA, Spain
2019/04/08 - 2019/04/12 POSTER. Vaz S., Macedo JC., Logarinho E. FoxM1 inhibition-driven aging signature in cancer cells improves sensitivity to anti-mitotic chemotherapeutics. Conferences Jacques Monod: Mitotic and Meiotic Cell Cycle control and execution, Roscoff, France.
Conference
 Conferences Jacques Monod: Mitotic and Meiotic Cell Cycle control and execution
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/03/30 - 2019/03/30 Invited speaker. Porque envelhecemos e como retardar o envelhecimento. https://www.publico.pt/2019/04/03/impar/noticia/retardar-envelhecimento-sim-possivel-segundo-medicos-1867827
Congress
 1.º Congresso Nacional de Estética, Beleza e Saúde
Health for Beauty, Portugal
2018/08/25 - 2018/08/28 POSTER. Transcriptional cis regulation of FOXM1 during aging. Ferreira FJ, Teixeira J, Galhardo M, Logarinho E*, Bessa J*. EMBL Conference - Transcription and Chromatin, Heidelberg, Germany.
Conference
 EMBL Conference - Transcription and Chromatin
2016/05/17 - 2016/05/21 POSTER. Loss of mitotic fidelity during human normative aging. Macedo J.C., Vaz S., Logarinho E. CSHL Cell Cycle Meeting, Cold Spring Harbor, US.
Meeting
 CSHL Cell Cycle Meeting 2016
Cold Spring Harbor Laboratory, United States
2011 - 2016 Course on Optical Microscopy Imaging to Bioscience - Lecture on Preparation and labelling techniques for light microscopy
Seminar
 Course on Optical Microscopy Imaging to Bioscience
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2015/12/12 - 2015/12/16 POSTER. Transcription factor FoxM1 prevents age-associated mitotic defects and aneuploidy. J.C. Macedo, S. Vaz, E. Logarinho. Annual Meeting of the American Society for Cell Biology, San Diego Convention Center, CA, US.
Meeting
 Annual Meeting of the American Society for Cell Biology
American Society for Cell Biology, United States
2013/06/22 - 2013/06/26 POSTER. Aging and Mitotic Misregulation. Macedo J.C., Gomes M., Logarinho E. EMBO Workshop on Chromosome Segregation and Aneuploidy, Breukelen, The Netherlands.
Workshop
 EMBO Workshop on Chromosome Segregation and Aneuploidy
2007/12/11 - 2007/12/12 Workshop Digital processing of microscopy images
Workshop
 Digital processing of microscopy images
Universidad Autónoma de Madrid, Spain
1998/09 - 1998/09 EMBO Course “The Yeast Two-Hybrid system”, Genzentrum LMU, Munich
Workshop
 EMBO Course “The Yeast Two-Hybrid system”
Ludwig-Maximilians-Universität München Genzentrum, Germany

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/02/23 PhD Thesis Arguer. Title: A molecular understanding of aneuploid cell clearance
(Thesis) Main arguer
 Valentino Martis (PhD)
European School of Molecular Medicine, Italy
2023/06/27 MD thesis member (Supervisor). Title: The fundamental principles of cell cycle control: what goes wrong with aging?
Supervisor
 Ana Rita Araújo (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/01/06 PhD thesis member (Supervisor). Title: Human hair follicle regeneration - from molecular mechanisms to therapeutic targeting.
Supervisor
 Ana Rita de Sousa Castro (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
2022/12/19 MSc Thesis Arguer. Title: Development of a cellular ataxin-3 protein-protein interaction (PPI) assay for high-throughput screening of PPI modifiers
(Thesis) Main arguer
 Ana Rita Ferreira Fernandes (Master)
Universidade do Minho Escola de Medicina, Portugal
2022/11/29 MSc Thesis Arguer. Title: Deciphering the in vivo mechanisms underlying the IL-10-mediated differentiation of IFNg-producing T cells
(Thesis) Main arguer
 Tânia Filipa Antunes Lima (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022/01/11 PhD Thesis Member (Supervisor). Transcriptional cis regulation of the FOXM1 coding gene during ageing
Thesis Member
 Fábio Júnio Ferreira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/07/09 PhD Thesis Member (Supervisor). Age-dependent sensitivity to antimitotics: the role of FOXM1 and its therapeutic potential
Thesis Member
 Sara Marisa Vaz (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/03/18 MSc Thesis Jury Member (Supervisor). Title: Effect of senolytic anti-aging compounds in Down Syndrome-driven senescence.
Supervisor
 Raquel Alves da Silva (Master)
Universidade Nova de Lisboa, Portugal
2021/01/28 MSc Thesis Main Arguer. Title: Describing monolayer mechanoresponse from nuclear morphology and dynamics: a computational approach
(Thesis) Main arguer
 Maria Teresa Bento Parreira (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/12 PhD Thesis Arguer. Title: Exploring the consequences of chromosomal instability in cancer
(Thesis) Arguer
 Lin Zhou (PhD)
Rijksuniversiteit Groningen, Netherlands
2020/09/28 PhD Thesis Member (Co-supervisor). Nucleolar stress as an aging hallmark: the role of NOL12 and FoxM1
Thesis Member
 Marta Andreia de Ribeiro Pinho (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/07/17 PhD Thesis Main Arguer. Title: On the Role of Senescent Cells in Spinal Cord Injury
(Thesis) Main arguer
 Diogo de Abreu Paramos de Carvalho (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/07/23 PhD Thesis Member. Title: The role of signaling lipids in the nervous system physiology and pathology: mechanistic insights of the phospholipase D pathway in neurodegenerative diseases
Thesis Member
 Ana Francisca Rodrigues Vaz Bravo (PhD)
Universidade do Minho Escola de Medicina, Portugal
2017/12/06 MSc Thesis Main Arguer. CLASP2 functional domains - role in kinetochore microtubule dynamics and mitotic fidelity
(Thesis) Main arguer
 Hugo Miguel Oliveira Girão (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2015/11/03 MSc Thesis Main Arguer. Topic: Centrosome clustering
(Thesis) Main arguer
 Katharina Santos das Dores (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/11/21 MSc Thesis Main Arguer. Topic: Chromosome cohesion decay
(Thesis) Main arguer
 Mariana Batista Santos (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/05/22 PhD Thesis Member. Title: Kinetochore-microtubule interaction and regulation.
Thesis Member
 Tália Cláudia Feijão Moreira Figueiredo (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/11/08 MSc Thesis main arguer. Title: Study of the expression levels of MAD2L2, BUB1, BUB1B and KIF2C human genes in miscarriage aneuploid samples.
(Thesis) Main arguer
 Raquel Sofia Conde Ribeiro (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2012/04 Member of the Jury, PhD in Biomedical Sciences. Thesis entitled: New insight into translation during yeast programmed cell death.
Thesis Member
 Maria Alexandra Oliveira da Silva (PhD)
Universidade do Minho Escola de Medicina, Portugal
2011/11 MSc Thesis Main Arguer. Title: Searching for therapeutic compounds in a transgenic Caenorhabditis elegans model of Machado Joseph disease.
(Thesis) Main arguer
 AnaLuisa de Jales Monteiro de Sousa (Master)
Universidade do Minho Escola de Ciências, Portugal
2008/11 PhD Thesis member. Title: C. elegans ataxin-3: function, loss-of-function and molecular partners.
Thesis Member
 Ana João Rodrigues (PhD)
Universidade do Minho Escola de Medicina, Portugal
2007/10/09 MSC Thesis Main Arguer. Title: Molecular Dissection of CLASPS Function in Mitosis: A Proteomic Approach.
(Thesis) Main arguer
 Ana Rita Ramada Maia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2007/07/25 PhD Thesis member. Title: Identification and characterization of ataxin-3 molecular interactors.
Thesis Member
 Anabela da Conceição Coelho Pinto Ferro (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/03 MSc Thesis member. Title: In vivo dynamics of ataxin-3 aggregation in Caenorhabditis elegans neurons.
Thesis Member
 Andreia Cristiana Teixeira de Castro (Master)
Universidade do Minho Escola de Ciências, Portugal
2006/03 PhD Thesis Main Arguer. Title: Characterization of Mob1-like proteins in Drosophila: DMob4 is a new tumor suppressor gene.
(Thesis) Main arguer
 Célia Maria Monteiro Domingues (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2005/01 PhD Thesis Main Arguer. Thesis entitled: Cell cycle regulation during Drosophila wing imaginal disc development: negative regulation of dE2F1 by cyclin dependent kinases controls cell cycle timing.
(Thesis) Main arguer
 Tânia Reis de Almeida Bastos (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Committee member

Activity description
Role 		Institution / Organization
2019/11/23 - 2023 Restricted Scientific Council of i3S - Elected vice-coordinator of the Cancer Integrative Program
Coordinator
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/11/23 - 2023 Restricted Scientific Council of IBMC - Elected representative of the Cancer Integrative Program
Member
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/11/23 - 2023 Executive Council of IBMC - Elected representative of the Cancer Integrative Program
Member
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Conference scientific committee

Conference name Conference host
2024/06/13 - 2024/06/13 One Health PhD Forum, 1st edition Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Mestrado Medicina Geriátrica - Lecture in Aging Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2015 - Current MCBiology PhD Program - Lecture in Aging and Aneuploidy Biologia Molecular e Celular Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - Current Cellular and Molecular Biology MSc Program - Lectures in Cell Cycle and Mitosis Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2018 GABBA PhD Program - Lecture in Cell Division/Mitosis Graduate Program in Areas of Basic and Applied Biology (Doutoramento) Universidade do Porto, Portugal
2015/02/09 - 2015/02/13 PGCD PhD Program - Lectures in The working cell (cell cycle, cytoskeleton and cancer) Programa de Pós-Graduação Ciência para o Desenvolvimento (Doutoramento) Instituto Gulbenkian de Ciência, Portugal

Universidade de Cabo Verde, Cape Verde
2013/09/15 - 2014/09/15 Invited Assistant Professor 20% Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2007/02/01 - 2009/01/31 Assistant Professor full-time Medicina (Mestrado integrado) Universidade do Minho Escola de Medicina, Portugal
2007/02/01 - 2009/01/31 Assistant Professor full-time Medicina (Mestrado integrado) Universidade do Minho Escola de Medicina, Portugal
2002/02/01 - 2007/01/31 Assistant Professor full-time Ciências Farmacêuticas (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2002/02/01 - 2007/01/31 Assistant Professor full-time Medicina Dentária (Mestrado integrado) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2002/02/01 - 2007/01/31 Assistant Professor full-time Psicologia Clínica (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2001/01/01 - 2002/01/31 Assistant Teacher full time Ciências Farmacêuticas (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
1999/10/01 - 2000/12/31 Assistant Teacher (20%) Medicina Dentária (Licenciatura) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
1994/10/01 - 1999/07/31 Assistant Teacher (20%) Anatomia Patológica, Citológica e Tanatológica (Bacharelato) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020/02 - Current Expert grant evaluator Medical Research Council (MRC) Molecular and Cellular Medicine Board
Evaluator
 Medical Research Council, United Kingdom
2020/02 - Current Expert grant evaluator DKFZ-MOST Germany-Israel Cooperation in Cancer Research
Evaluator
 Deutsches Krebsforschungszentrum Zentralbibliothek, Germany
2019/12 - Current Expert grant evaluator United States-Israel Binational Science Foundation
Evaluator
 Binational Science Foundation, Israel
2018/07/30 - Current Expert evaluator for the BBSRC Discovery Fellowships /UK Research and Innovation
Evaluator
 Biotechnology and Biological Sciences Research Council, United Kingdom
2023/07 - 2023/07 Expert evaluator for the World Wide Cancer Research Grants
Evaluator
 Worldwide Cancer Research, United Kingdom Worldwide Cancer Research
2023/02/27 - 2023/06/20 Member of the jury - Call for Assistant Researcher in Biomedical Sciences, University of Aveiro CI-CTTI-136-SGRH/2022 - Aviso n.º 20100/2022
Evaluator
 Universidade de Aveiro, Portugal
2022/06/20 - 2022/07/26 Expert grant evaluator Worldwide Cancer Research
Evaluator
 Worldwide Cancer Research, United Kingdom Worldwide Cancer Research
2021 - 2021 PhD Fellowships Evaluation Panel - Biomedicine
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2020 - 2020 PhD Fellowships Evaluation Panel - Biomedicine
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2019/06/24 - 2019/06/25 PhD Fellowships Evaluation Panel - Biomedicine
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2024/01 Interview (magazine). Porque envelhecemos e como garantir uma longevidade saudável? Revista da Misericórdia de Santo Tirso #46
2023/06/08 Comment (newspaper). A taurina não dá asas, mas é uma nova candidata a “elixir da juventude”. Comment/digest on the news about paper published in Science. Jornal Público
2022/05/24 News (magazine). i3S descobre gene que atrasa envelhecimento e aumenta a vida saudável notícias.up.pt
2022/05/21 News (newspaper). Como um gene pode abrandar o envelhecimento e aumentar a longevidade em 30%. Highlight on our work published in Nature Aging 2022. Jornal Público
2021/12/17 News (magazine). Equipa do i3S recebe financiamento para estudar Síndrome de Down notícias.up.pt
2021/12/16 News (magazine). Investigadores do i3S estudam envelhecimento prematuro de pacientes com Síndrome de Down. Highlight on our grant award from the Jérôme Lejeune Foundation. saudeonline.pt
2021/08/11 Interview (newspaper). Em busca dos segredos da longevidade. Elsa Logarinho's laboratory at I3S in Porto is studying ways to delay ageing and extend the healthy life span. Diário de Notícias
2021/06/17 News (magazine). Investigação do i3s associa gene da juventude a regeneração do tecido muscular notícias.up.pt
2021/06/15 News (newspaper). Estudo conclui que gene da juventude tem impacto na regeneração do tecido muscular. Highlight on our work published in Cells 2021. Diário de Notícias
2021/06/14 News (magazine). Estudo conclui que gene da juventude tem impacto na regeneração do tecido muscular. Highlight on our work published in Cells 2021. visa.pt/visaosaude
2020/11/04 News (magazine). Fundação norte-americana financia terapia de rejuvenescimento do i3S notícias.up.pt
2020/11/04 News (newspaper). Bolsa norte-americana impulsiona i3S a avançar com terapia para doença infantil rara. Highlight on our grant from Progeria Research Foundation. Jornal Público
2020/11/04 News (newspaper). Investigadora do Porto ganha bolsa nos EUA para terapia contra doença rara de envelhecimento infantil. Highlight on our grant ward from the Progeria Research Foundation. Diário de Notícias
2020/11 Interview (magazine). Elsa Logarinho: à conquista do elixir da juventude notícias.up.pt
2020/05/07 News (magazine). Investigadores do i3S descobrem composto que rejuvenesce as células. notícias.up.pt
2020/05/07 News (magazine). Investigadores do i3S avançam na descoberta de novas terapias anti-envelhecimento. highlight on our work published in Embo Reports 2020. www.porto.pt/pt/noticia
2020/05/06 News (newspaper). Investigadores do Instituto de Investigação e Inovação em Saúde (i3S) da Universidade do Porto descobriram um composto que, ao corrigir a instabilidade do material genético, pode vir a ser usado como terapia anti-envelhecimento. Highlight on our work published in Embo Rep 2020. Observador
2019/03/08 Interview (newspaper). "Elsa Logarinho: A bioquímica que descobriu o gene da juventude" Jornal de Notícias
2019/01/28 Comment (newspaper). Estamos a viver mais, mas nem sempre melhor. Novos medicamentos prometem livrar-nos das doenças da idade. Talvez nos possam rejuvenescer. Será este um mergulho na Fonte da Juventude? Observador
2019/01/02 Interview (newspaper). Sobrinho Simões, médico, 71 anos, investigador na área do cancro, e Elsa Logarinho, 46 anos, especialista em genética e líder da equipa que descobriu o gene da juventude, falam sobre as doenças e a sociedade que aí vem. Diário de Notícias
2018/08/23 News (magazine). Investigação do i3S descobre “gene da juventude” que pode reverter o envelhecimento celular da pele. highlight on our work published in Nature Communications 2018. newspharma.pt
2018/08/07 News (magazine). Investigadores do Porto descobrem "gene da juventude" que pode reverter o envelhecimento celular. Highlight on our work published in Nature Communications 2018 timeout.pt/porto/
2018/08/03 News (magazine). Investigadores do i3S descobrem o gene da juventude. Notícias.up.pt
2018/08/03 News (newspaper). Descoberta ligação entre um gene e o envelhecimento. Highlight on our work published in Nature Communications 2018. Jornal Público
2015/07/07 News (newspaper). "Erros na divisão celular explicam resistência de células cancerosas às terapias" O vídeo do estudo liderado por investigadora portuguesa mostra uma célula humana em divisão irregular e foi destacado como a Imagem Biomédica do Dia pelo Imperial College de Londres. Público
2011/11/17 News (newspaper). Pfizer Prize 2011. Pelo seu contributo para a compreensão da divisão celular, Elsa Logarinho e Hélder Maiato, do Instituto de Biologia Molecular e Celular (IBMC) do Porto, partilham os 20 mil euros do prémio de investigação básica Público

Interview (tv / radio show)

Program Topic
2023/12/26 - 2023/12/28 Documentary (tv RTP channel). 100 ou mais, 3 episódios - Corpo, Mente, Viver mais. Invited researcher to discuss biology of aging. Aging
2021/12/16 - 2021/12/16 News (tv). Investigadores estudam envelhecimento prematuro de pacientes com Síndrome de Down. Highlight on our grant from Jérôme Lejeune Foundation
2021/11 - 2021/11 Interview (tv talk-show). Vamos beber um café e falar sobre isso, episode 3/26. José Navarro de Andrade talks to researcher Elsa Logarinho about ageing, a topic she researches at the I3S laboratory in Porto.
2021/06/14 - 2021/06/14 News (tv). Gene da juventude tem impacto na regeneração do tecido muscular. Highlight on our work published in Cells 2021
2020/11/26 - 2020/11/26 Documentary (tv RTP channel). Já não sou quem era, episódio 29/49. Invited researcher to discuss the biology of aging. Aging
2020/11/24 - 2020/11/24 Radio podcast. Capa à contracapa: Genética, stress crónico e envelhecimento. Duas investigadoras, bioquímica Elsa Logarinho e a psicóloga Constança Paúl, discutem o tema. Ageing, genetics and chronic stress
2019/10/07 - 2019/10/07 Interview (radio). Nobel da Medicina: Porque é que a descoberta distinguida é tão importante? TSF spoke to two researchers from i3S, Elsa Logarinho and Angela Costa, to understand the importance of the discovery made by William Kaelin, Sir Peter Ratcliffe and Gregg Semenza, who were awarded the Nobel Prize for Medicine.
2018/11/08 - 2018/11/08 Interview. "90 segundos de ciência, EP. 488" ELSA LOGARINHO – GRUPO DE INVESTIGAÇÃO DESCOBRE RELAÇÃO ENTRE UM GENE E O ENVELHECIMENTO
2018/10/22 - 2018/10/22 Interview. #i3S researcher Elsa Logarinho is one of the latest guests on "Mentes que Brilham" (16'20''), where she talked about her ongoing research focused on #ageing processes.#i3Snews

Mentoring / Tutoring

Topic Student name
2022 - 2024 PhD Student External Advisor Catarina Milheiro Soares da Silva
2020/01/01 - 2023/12/31 PhD Student External Advisor. School of Medicine, University of Minho, Portugal. (Supervisor: Patricia Maciel) Liliana Sofia Meireles da Costa
2019 - 2022 PhD Student External Advisor. Sonia Viganò
Distinctions

Award

2022 Maximom Longevity Prize
Maximom AG, Switzerland
2013 SPGH Award for the best portuguese work in Genetics 2012
Sociedade Portuguesa de Genética Humana, Portugal
2011 Pfizer Award for Basic Research
Sociedade de Ciências Médicas de Lisboa, Portugal
2007 CESPU 2007 International Award for Scientific Research, 2nd honorable mention
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2001 Jacinto Magalhães Award for the best portuguese work in Genetics
Centro de Genética Médica Doutor Jacinto Magalhães, Portugal

Other distinction

2023 Best Poster Prize in Basic Research - 20th EHRS Meeting
European Hair Research Society, United Kingdom
2019 Best poster prize - i3S Annual Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 Mulheres na Ciência - 2ª edição 2019
Ciência Viva, Portugal